Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	GBF1 PRR5 ARHGAP17 DENND1A DENND2B FARP2 ARFGAP2 HPS1 AGFG2 ARHGEF2 SIPA1L2 RIC1 TNS3	3.22e-05	507	132	13	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	GBF1 PRR5 ARHGAP17 DENND1A DENND2B FARP2 ARFGAP2 HPS1 AGFG2 ARHGEF2 SIPA1L2 RIC1 TNS3	3.22e-05	507	132	13	GO:0030695
GeneOntologyMolecularFunction	transcription coregulator binding	ATF7 SP1 HNF1A PCLO MED1 PHF1	3.39e-04	140	132	6	GO:0001221
GeneOntologyMolecularFunction	endopolyphosphatase activity	NUDT11 NUDT10	4.28e-04	5	132	2	GO:0000298
GeneOntologyMolecularFunction	bis(5'-adenosyl)-hexaphosphatase activity	NUDT11 NUDT10	4.28e-04	5	132	2	GO:0034431
GeneOntologyMolecularFunction	diphosphoinositol-polyphosphate diphosphatase activity	NUDT11 NUDT10	4.28e-04	5	132	2	GO:0008486
GeneOntologyMolecularFunction	structural constituent of nuclear pore	NUP58 POM121 POM121B	5.84e-04	25	132	3	GO:0017056
GeneOntologyMolecularFunction	chitinase activity	CHIA CHIT1	6.39e-04	6	132	2	GO:0004568
GeneOntologyMolecularFunction	bis(5'-adenosyl)-pentaphosphatase activity	NUDT11 NUDT10	6.39e-04	6	132	2	GO:0034432
GeneOntologyMolecularFunction	nuclear localization sequence binding	NUP58 POM121 POM121B	7.35e-04	27	132	3	GO:0008139
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	GBF1 DENND1A DENND2B FARP2 HPS1 ARHGEF2 RIC1	8.78e-04	231	132	7	GO:0005085
GeneOntologyMolecularFunction	chitin binding	CHIA CHIT1	1.18e-03	8	132	2	GO:0008061
Domain	Chitin-bd_dom	CHIA CHIT1	4.66e-05	2	128	2	IPR002557
Domain	CBM_14	CHIA CHIT1	4.66e-05	2	128	2	PF01607
Domain	CHIT_BIND_II	CHIA CHIT1	4.66e-05	2	128	2	PS50940
Domain	-	CHIA CHIT1	4.66e-05	2	128	2	2.170.140.10
Domain	ChtBD2	CHIA CHIT1	4.66e-05	2	128	2	SM00494
Domain	AKAP_110_C	AKAP3 SPHKAP	1.39e-04	3	128	2	IPR018292
Domain	GRIN_C	GPRIN3 GPRIN1	1.39e-04	3	128	2	PF15235
Domain	GRIN_C	GPRIN3 GPRIN1	1.39e-04	3	128	2	IPR032745
Domain	SPHK1-interactor_AKAP_110	AKAP3 SPHKAP	2.77e-04	4	128	2	IPR008382
Domain	AKAP_110	AKAP3 SPHKAP	2.77e-04	4	128	2	PF05716
Domain	-	CHIA CHIT1	4.60e-04	5	128	2	3.10.50.10
Domain	Chitinase_insertion	CHIA CHIT1	4.60e-04	5	128	2	IPR029070
Domain	Glyco_hydro_18_chit_AS	CHIA CHIT1	6.87e-04	6	128	2	IPR001579
Domain	PH_dom-like	PDPK1 PLEKHA6 PPP4R3A FARP2 PHLPP1 NUMB PLCB2 OSBP2 ARHGEF2 TNS3	7.11e-04	426	128	10	IPR011993
Domain	C2_dom	SYT3 PCLO ESYT2 PRKCE PLCB2 TNS3	9.39e-04	164	128	6	IPR000008
Domain	Glyco_hydro18_cat	CHIA CHIT1	9.57e-04	7	128	2	IPR001223
Domain	Glyco_hydro_18	CHIA CHIT1	9.57e-04	7	128	2	PF00704
Domain	Chitinase_II	CHIA CHIT1	9.57e-04	7	128	2	IPR011583
Domain	Glyco_18	CHIA CHIT1	9.57e-04	7	128	2	SM00636
Domain	CHITINASE_18	CHIA CHIT1	9.57e-04	7	128	2	PS01095
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 GBF1 ARID3A BICRA ADGRB2 ARHGAP17 FYCO1 CEP192 MLLT10 ARID1A PRAG1 DENND1A EML3 ZNF503 RABL6 SCAF1 EHBP1L1 KMT2D SHANK2 CELSR3 MAP1S CASKIN1 SCN5A PCNX1 ARHGEF2 SNAPC4 SIPA1L2 MBD5 WNK2 RIC1 PRRC2B	1.62e-18	1105	132	31	35748872
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SECISBP2L GBF1 GPRIN3 PLEKHA6 KHDC4 PPP4R3A FARP2 ZNF462 AHRR POM121 FHDC1 PEAK1 MBD5 POM121B RIC1	7.18e-10	493	132	15	15368895
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ATF7 NRIP1 HDAC4 BICRA PRR5 BLNK CEP192 ARID1A DENND1A MAP3K12 DENND2B FARP2 KLHL29 ZNF462 ESYT2 SHANK2 PTPRE MICAL2 KCNJ3 NUMB PRKCE MBD5 WNK2 RIC1	1.91e-09	1489	132	24	28611215
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SP1 GBF1 PDPK1 MED1 RREB1 GPRIN1 SF1 PPP4R3A SCAF1 ESYT2 KMT2D DDX46 SEC24C MAP1S ARHGEF2 SNAPC4 BAG6	6.72e-09	774	132	17	15302935
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SP1 GBF1 HDAC4 BICRA MLLT10 POM121 MAP1S KCNJ3 NUMB MAML2 WNK2 RIC1	1.00e-07	430	132	12	35044719
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	GBF1 HDAC4 PRR5 ARHGAP17 CEP192 PRAG1 DENND1A DENND2B ARFGAP2 ESYT2 NUMB PRKCE PEAK1 ARHGEF2 SIPA1L2 TNS3	1.88e-07	861	132	16	36931259
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	ATF7 ARID3A HDAC4 BICRA MED1 RREB1 ARID1A KHDC4 SF1 PPP4R3A ZNF503 KMT2D UBR5 BIN2 ARHGEF2 BAG6 PRRC2B RAD23A	2.09e-07	1103	132	18	34189442
Pubmed	Impact of WIN site inhibitor on the WDR5 interactome.	PDPK1 ZNF462 KMT2D UBR5 ARHGEF2	6.26e-07	43	132	5	33472061
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	PDXDC1 TNIK PRR5 GPRIN3 PLEKHA6 GPRIN1 FARP2 ESYT2 NUMB PEAK1 SIPA1L2	6.70e-07	421	132	11	36976175
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TNIK HDAC4 SYT3 ADGRB2 FYCO1 ZNF462 SHANK2 SEC24C UBR5 CASKIN1 SPHKAP PRKCE ARHGEF2 TAF5 WNK2 PRRC2B	8.29e-07	963	132	16	28671696
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	PDPK1 SLC6A17 PCLO PLEKHA6 GPRIN1 SHANK2 CASKIN1 PRKCE ARHGEF2 SIPA1L2	9.13e-07	347	132	10	17114649
Pubmed	Interaction network of human early embryonic transcription factors.	ARID3A HDAC4 BICRA NUP58 RREB1 ARID1A ZNF503 ZNF462 KMT2D PRRC2B	1.01e-06	351	132	10	38297188
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	GBF1 HDAC4 KIAA1549 R3HDM2 CEP192 ARID1A DENND1A MAP1S UBR5 ARHGEF2 SIPA1L2	1.18e-06	446	132	11	24255178
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	PDXDC1 TNIK KIAA1549 CDHR5 PLEKHA6 FARP2 ESYT2 EHBP1L1 MICAL2 NUMB PEAK1 TNS3	1.93e-06	569	132	12	30639242
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	BICRA R3HDM2 KHDC4 SF1 ZNF503 SPTY2D1 PRRC2B	1.98e-06	152	132	7	38360978
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	TNIK PCLO R3HDM2 PRAG1 PEAK1 ARHGEF2 SIPA1L2 PRRC2B	1.98e-06	218	132	8	33378226
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	SECISBP2L TNIK PDPK1 FYCO1 PLEKHA6 DENND1A FARP2 RABL6 ARFGAP2 SHANK2 SEC24C UBR5 NFKBIE AGFG2 NUMB TNS3	2.19e-06	1038	132	16	26673895
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ATF7 SP1 HNF1A SALL3 ARID3A PBX4 MLLT10 ARID1A SF1 ZNF462 PHF1 ARFGAP2 SNAPC4 FOXH1	2.60e-06	808	132	14	20412781
Pubmed	A human MAP kinase interactome.	SP1 HDAC4 BICRA ARHGAP17 PLEKHA6 NUP58 PPP4R3A POM121 PRKCE MBD5 WNK2	2.69e-06	486	132	11	20936779
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	NRIP1 SALL3 UBQLN4 MED1 ARID1A ZNF462 KMT2D	3.69e-06	167	132	7	20362541
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	KIAA1549 ARID1A RABL6 POM121 NUMB PEAK1 SIPA1L2 PRRC2B	7.89e-06	263	132	8	34702444
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	KIAA1549 GPRIN3 CEP192 ARID1A GPRIN1 PPP4R3A ESYT2 KMT2D PTPRE PHLPP1 NUMB PEAK1 ARHGEF2 PRRC2B TNS3	1.13e-05	1049	132	15	27880917
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	TNIK PCLO ADGRB2 GPRIN1 PRAG1 SHANK2 UBR5 PRKCE	1.27e-05	281	132	8	28706196
Pubmed	An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase.	NUDT11 NUDT10	1.43e-05	2	132	2	12105228
Pubmed	Inhibition of CHIT1 as a novel therapeutic approach in idiopathic pulmonary fibrosis.	CHIA CHIT1	1.43e-05	2	132	2	35122869
Pubmed	PKCepsilon is a permissive link in integrin-dependent IFN-gamma signalling that facilitates JAK phosphorylation of STAT1.	PDPK1 PRKCE	1.43e-05	2	132	2	12640464
Pubmed	Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases.	PRAG1 PEAK1	1.43e-05	2	132	2	27531744
Pubmed	Evaluation of AMCase and CHIT-1 expression in monocyte macrophages lineage.	CHIA CHIT1	1.43e-05	2	132	2	23129258
Pubmed	Changes in protein kinase C epsilon phosphorylation status and intracellular localization as 3T3 and 3T6 fibroblasts grow to confluency and quiescence: a role for phosphorylation at ser-729?	PDPK1 PRKCE	1.43e-05	2	132	2	11062054
Pubmed	LPS depletes PHLPP levels in macrophages through the inhibition of SP1 dependent transcriptional regulation.	SP1 PHLPP1	1.43e-05	2	132	2	28322791
Pubmed	Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases.	NUDT11 NUDT10	1.43e-05	2	132	2	12689335
Pubmed	Identification of a novel acidic mammalian chitinase distinct from chitotriosidase.	CHIA CHIT1	1.43e-05	2	132	2	11085997
Pubmed	PKCepsilon stimulated arginine methylation of RIP140 for its nuclear-cytoplasmic export in adipocyte differentiation.	NRIP1 PRKCE	1.43e-05	2	132	2	18628823
Pubmed	Characterization of four novel CAG repeat-containing cDNAs.	R3HDM2 KMT2D	1.43e-05	2	132	2	8595911
Pubmed	Chitinolytic activity in nasal polyps.	CHIA CHIT1	1.43e-05	2	132	2	21711963
Pubmed	Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association.	PRAG1 PEAK1	1.43e-05	2	132	2	29079850
Pubmed	UBQLN4 recognizes mislocalized transmembrane domain proteins and targets these to proteasomal degradation.	UBQLN4 BAG6	1.43e-05	2	132	2	27113755
Pubmed	Genetic association between human chitinases and lung function in COPD.	CHIA CHIT1	1.43e-05	2	132	2	22200767
Pubmed	PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins.	PEAK1 TNS3	1.43e-05	2	132	2	35687021
Pubmed	CHIT1 and AMCase expression in human gastric mucosa: correlation with inflammation and Helicobacter pylori infection.	CHIA CHIT1	1.43e-05	2	132	2	19242357
Pubmed	Increased expression of acidic mammalian chitinase and chitotriosidase in the nasal mucosa of patients with allergic rhinitis.	CHIA CHIT1	1.43e-05	2	132	2	20422678
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	PDXDC1 GBF1 ARHGAP17 NUP58 ARFGAP2 UBR5 ARHGEF2 BAG6	1.52e-05	288	132	8	23383273
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	TNIK CEP192 ESYT2 UBR5 PEAK1 SIPA1L2 TNS3	1.60e-05	209	132	7	36779422
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	PDPK1 UBQLN4 PRR5 RREB1 ZNF503 ZNF462 PHF1 KMT2D ARHGEF2 MBD5	2.07e-05	495	132	10	27705803
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	NRIP1 BICRA CECR2 PCLO RREB1 ARID1A ZNF503 ARFGAP2 KMT2D	2.26e-05	398	132	9	35016035
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	TNIK GBF1 ZNF462 ESYT2 UBR5 PHLPP1 PCNX1	2.57e-05	225	132	7	12168954
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TNIK R3HDM2 CEP192 KLHL29 SEC24C UBR5 SPHKAP SIPA1L2 PRRC2B	2.69e-05	407	132	9	12693553
Pubmed	Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.	ARHGAP17 MED1 PHLPP1	2.89e-05	16	132	3	27721240
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	PCLO PLEKHA6 GPRIN1 SHANK2 CASKIN1 PEAK1 PRRC2B	3.04e-05	231	132	7	16452087
Pubmed	PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.	GPRIN3 GPRIN1 PTPRE NUMB PEAK1	3.06e-05	94	132	5	32062451
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CECR2 KIAA1549 NUP58 DDX46 CELSR3 CASKIN1 PCNX1 MAML2 IGSF1 WNK2	3.63e-05	529	132	10	14621295
Pubmed	Chitinase effects on immune cell response in neuromyelitis optica and multiple sclerosis.	CHIA CHIT1	4.28e-05	3	132	2	21159721
Pubmed	Fungal exposure modulates the effect of polymorphisms of chitinases on emergency department visits and hospitalizations.	CHIA CHIT1	4.28e-05	3	132	2	20538957
Pubmed	Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction.	SF1 DDX46	4.28e-05	3	132	2	31110137
Pubmed	Regulation of novel protein kinase C epsilon by phosphorylation.	PDPK1 PRKCE	4.28e-05	3	132	2	11964154
Pubmed	POM121 inhibits the macrophage inflammatory response by impacting NF-κB P65 nuclear accumulation.	POM121 POM121B	4.28e-05	3	132	2	30802453
Pubmed	Blocking the association of HDAC4 with MAP1S accelerates autophagy clearance of mutant Huntingtin.	HDAC4 MAP1S	4.28e-05	3	132	2	26540094
Pubmed	The chitinase and chitinase-like proteins: a review of genetic and functional studies in asthma and immune-mediated diseases.	CHIA CHIT1	4.28e-05	3	132	2	19644363
Pubmed	Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.	POM121 POM121B	4.28e-05	3	132	2	35507432
Pubmed	Breast regression protein-39 is not required for experimental autoimmune encephalomyelitis induction.	CHIA CHIT1	4.28e-05	3	132	2	26079949
Pubmed	Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins.	SHANK2 CASKIN1	4.28e-05	3	132	2	31727973
Pubmed	SP1 Promotes HDAC4 Expression and Inhibits HMGB1 Expression to Reduce Intestinal Barrier Dysfunction, Oxidative Stress, and Inflammatory Response after Sepsis.	SP1 HDAC4	4.28e-05	3	132	2	35780770
Pubmed	The histone deacetylase 4/SP1/microrna-200a regulatory network contributes to aberrant histone acetylation in hepatocellular carcinoma.	SP1 HDAC4	4.28e-05	3	132	2	21837748
Pubmed	Single-cell Sequencing Reveals Variants in ARID1A, GPRC5A and MLL2 Driving Self-renewal of Human Bladder Cancer Stem Cells.	ARID1A KMT2D	4.28e-05	3	132	2	27387124
Pubmed	Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases.	NUDT11 NUDT10	4.28e-05	3	132	2	12121577
Pubmed	Identification and biochemical analysis of GRIN1 and GRIN2.	GPRIN3 GPRIN1	4.28e-05	3	132	2	15488195
Pubmed	Upregulation of PKCη by PKCε and PDK1 involves two distinct mechanisms and promotes breast cancer cell survival.	PDPK1 PRKCE	4.28e-05	3	132	2	23562764
Pubmed	Polymorphisms of chitinases are not associated with asthma.	CHIA CHIT1	4.28e-05	3	132	2	20226308
Pubmed	Association of immature hypophosphorylated protein kinase cepsilon with an anchoring protein CG-NAP.	PDPK1 PRKCE	4.28e-05	3	132	2	10945988
Pubmed	HDAC4 inhibits the transcriptional activation of mda-7/IL-24 induced by Sp1.	SP1 HDAC4	4.28e-05	3	132	2	20383178
Pubmed	HDAC4 promotes growth of colon cancer cells via repression of p21.	SP1 HDAC4	4.28e-05	3	132	2	18632985
Pubmed	Transcriptional regulation of oncogenic protein kinase Cϵ (PKCϵ) by STAT1 and Sp1 proteins.	SP1 PRKCE	4.28e-05	3	132	2	24825907
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXE1 ATF7 SP1 HNF1A KIAA1549 PBX4 RREB1 KMT2D SKOR1 SOHLH1 SNAPC4 FOXH1 EN1	4.44e-05	908	132	13	19274049
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	MED1 ARID1A GPRIN1 KMT2D DDX46 NFKBIE NUMB PEAK1 TAF5 PRRC2B	4.95e-05	549	132	10	38280479
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	GBF1 RREB1 RABL6 ARFGAP2 SEC24C ARHGEF2 PRRC2B	5.14e-05	251	132	7	29778605
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	PDXDC1 PLEKHA6 GPRIN1 ARFGAP2 ESYT2 EHBP1L1 SHANK2 NFKBIE NUMB PEAK1	6.28e-05	565	132	10	25468996
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	HDAC4 NUP58 ARID1A KHDC4 ZNF503 KMT2D POM121 AGFG2 PRRC2B	6.59e-05	457	132	9	32344865
Pubmed	Cancer gene mutation frequencies for the U.S. population.	ARID1A KMT2D	8.54e-05	4	132	2	34645806
Pubmed	Molecular mechanism of transcriptional repression of AhR repressor involving ANKRA2, HDAC4, and HDAC5.	HDAC4 AHRR	8.54e-05	4	132	2	17949687
Pubmed	Beyond conventional chemotherapy: Emerging molecular targeted and immunotherapy strategies in urothelial carcinoma.	ARID1A KMT2D	8.54e-05	4	132	2	26138514
Pubmed	Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate.	NUDT11 NUDT10	8.54e-05	4	132	2	12370170
Pubmed	8-oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factors.	SP1 TAF5	8.54e-05	4	132	2	24489103
Pubmed	MKK7 transcription positively or negatively regulated by SP1 and KLF5 depends on HDAC4 activity in glioma.	SP1 HDAC4	8.54e-05	4	132	2	30963560
Pubmed	Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes.	POM121 POM121B	8.54e-05	4	132	2	17900573
Pubmed	Auto-regulation of the Sohlh1 gene by the SOHLH2/SOHLH1/SP1 complex: implications for early spermatogenesis and oogenesis.	SP1 SOHLH1	8.54e-05	4	132	2	25003626
Pubmed	MiR-492 impairs the angiogenic potential of endothelial cells.	SP1 PDPK1	8.54e-05	4	132	2	23802567
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	SP1 HNF1A ARID3A MLLT10 ARID1A RTN2 SF1 ZNF462 PHF1 AHRR NFKBIE	8.70e-05	709	132	11	22988430
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	PDXDC1 TNIK GPRIN3 GPRIN1 ESYT2 EHBP1L1 NUMB PEAK1	1.01e-04	377	132	8	38117590
Pubmed	Human transcription factor protein interaction networks.	SP1 HNF1A ARID3A BICRA R3HDM2 CEP192 MLLT10 RREB1 ARID1A ZNF503 ZNF462 KMT2D NFKBIE TAF5 EN1 PRRC2B	1.08e-04	1429	132	16	35140242
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SYT3 PCLO KIAA1549 PLEKHA6 ARID1A SHANK2 SEC24C MAP1S MICAL2 CASKIN1 PRKCE PEAK1 ARHGEF2 SIPA1L2 WNK2 PRRC2B	1.09e-04	1431	132	16	37142655
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	TNIK PCLO ADGRB2 GPRIN1 ARFGAP2 ESYT2 SHANK2 MAP1S KCNJ3 CASKIN1 SPHKAP PEAK1 SIPA1L2 WNK2	1.14e-04	1139	132	14	36417873
Pubmed	Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates.	UBQLN4 UBR5 BAG6 RAD23A	1.19e-04	66	132	4	24811749
Pubmed	Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer.	NUDT11 NUDT10	1.42e-04	5	132	2	18264098
Pubmed	Gene repressive activity of RIP140 through direct interaction with CDK8.	NRIP1 MED1	1.42e-04	5	132	2	21868449
Pubmed	HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism.	SP1 HDAC4	1.42e-04	5	132	2	18850004
Pubmed	Protein kinase C(mu) regulation of the JNK pathway is triggered via phosphoinositide-dependent kinase 1 and protein kinase C(epsilon).	PDPK1 PRKCE	1.42e-04	5	132	2	12223477
Pubmed	Transcriptional regulation of N-acetylglutamate synthase.	SP1 HNF1A	1.42e-04	5	132	2	22383952
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	HDAC4 KIAA1549 CELSR3 IGSF1 MBD5	1.43e-04	130	132	5	12421765
Pubmed	Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8.	HDAC4 ZNF462 BAG6	1.63e-04	28	132	3	25752541
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	PDXDC1 GPRIN3 CEP192 GPRIN1 RABL6 ARFGAP2 SEC24C UBR5 PEAK1 SPTY2D1 PRRC2B	1.93e-04	777	132	11	35844135
Interaction	TOP3B interactions	VWA5B2 GBF1 ARID3A HDAC4 BICRA ADGRB2 ARHGAP17 R3HDM2 FYCO1 CEP192 MLLT10 ARID1A PRAG1 DENND1A EML3 ZNF503 RABL6 SCAF1 EHBP1L1 KMT2D SHANK2 CELSR3 MAP1S CASKIN1 SCN5A PCNX1 ARHGEF2 SNAPC4 SIPA1L2 MBD5 WNK2 RIC1 PRRC2B	1.58e-10	1470	130	33	int:TOP3B
Interaction	HNF4A interactions	SP1 NRIP1 HNF1A ARID3A HDAC4 BICRA MUC19 MED1 RREB1 ARID1A ZNF462 KMT2D TAF5	2.71e-08	275	130	13	int:HNF4A
Interaction	FEV interactions	ARID3A BICRA MLLT10 RREB1 ARID1A ZNF503 ZNF462 KMT2D TAF5 PRRC2B	8.04e-07	203	130	10	int:FEV
Interaction	CTBP1 interactions	TNIK SP1 NRIP1 HDAC4 PCLO MED1 RREB1 SF1 ARFGAP2 SEC24C MAML2 BAG6 PRRC2B	2.31e-06	406	130	13	int:CTBP1
Interaction	SERPINI2 interactions	UBQLN4 NUP58 PRKCE BAG6	4.72e-06	18	130	4	int:SERPINI2
Interaction	YWHAH interactions	NRIP1 GBF1 HDAC4 PDPK1 PRR5 ARHGAP17 R3HDM2 CEP192 MED1 PRAG1 DENND1A DENND2B EML3 ARFGAP2 ESYT2 NUMB PEAK1 ARHGEF2 SIPA1L2 WNK2 TNS3	7.58e-06	1102	130	21	int:YWHAH
Interaction	EGR2 interactions	ARID3A HDAC4 BICRA RREB1 ARID1A ZNF462 KMT2D PRRC2B	1.54e-05	171	130	8	int:EGR2
Interaction	MAGED1 interactions	HDAC4 RNF185 R3HDM2 CEP192 PHF1 POM121 UBR5 ARMC5 FOXH1 BAG6	2.20e-05	295	130	10	int:MAGED1
Interaction	GATA3 interactions	SP1 ARID3A HDAC4 MED1 ARID1A ZNF503 KMT2D PRRC2B	2.93e-05	187	130	8	int:GATA3
Interaction	SYNGAP1 interactions	TNIK ADGRB2 GPRIN1 SHANK2 UBR5 SPHKAP PRKCE PEAK1 ARHGEF2 SIPA1L2	3.09e-05	307	130	10	int:SYNGAP1
Interaction	CRX interactions	SP1 ARID3A BICRA RREB1 ARID1A ZNF462 KMT2D FOXH1 PRRC2B	4.07e-05	254	130	9	int:CRX
Interaction	GCM1 interactions	HDAC4 ARID1A ZNF503 KMT2D PRRC2B	7.78e-05	68	130	5	int:GCM1
Interaction	HIC1 interactions	SP1 HDAC4 ARID1A PHF1	8.30e-05	36	130	4	int:HIC1
Interaction	PTPRA interactions	GPRIN3 GPRIN1 PPP4R3A PTPRE NUMB PEAK1 BAG6	9.50e-05	164	130	7	int:PTPRA
Interaction	YWHAQ interactions	NRIP1 GBF1 HDAC4 PDPK1 UBQLN4 PRR5 R3HDM2 CEP192 MED1 DENND1A MAP3K12 DENND2B EML3 NUMB PRKCE PEAK1 ARHGEF2 SIPA1L2 TNS3	1.01e-04	1118	130	19	int:YWHAQ
Interaction	GJA1 interactions	PDXDC1 TNIK GBF1 UBQLN4 KIAA1549 GPRIN3 GPRIN1 ARFGAP2 ESYT2 NUMB PRKCE PEAK1 SIPA1L2	1.03e-04	583	130	13	int:GJA1
Interaction	PAX6 interactions	ARID3A BICRA FYCO1 RREB1 ARID1A ZNF503 ZNF462 KMT2D EN1 PRRC2B	1.33e-04	366	130	10	int:PAX6
Interaction	YWHAG interactions	HNF1A GBF1 HDAC4 PDPK1 PRR5 ARHGAP17 R3HDM2 CEP192 PRAG1 DENND1A DENND2B EML3 FARP2 ESYT2 NUMB PRKCE PEAK1 ARHGEF2 SIPA1L2 TNS3	1.45e-04	1248	130	20	int:YWHAG
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	ATF7 SP1 R3HDM2 PMEL MAP3K12 KMT2D BIN2	2.35e-04	423	132	7	chr12q13
Cytoband	9q34.3	CEL RABL6 SOHLH1 SNAPC4	2.58e-04	106	132	4	9q34.3
GeneFamily	Chitinases	CHIA CHIT1	5.64e-04	7	95	2	816
Coexpression	GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_UP	PILRB CDHR5 EML3 SF1 PHF1 HPS1 SCN5A PHLPP1 IGSF1 TREML2	6.60e-08	199	131	10	M3182
Coexpression	GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_DN	R3HDM2 NUP58 MED1 ARID1A MEIS3P1 PPP4R3A PHF1 PHLPP1	6.94e-06	197	131	8	M3193
Coexpression	GSE32423_CTRL_VS_IL7_MEMORY_CD8_TCELL_UP	ATF7 SYT3 MUC13 GPRIN1 PHLPP1 GSDMA PCNX1 MAML2	7.20e-06	198	131	8	M5083
Coexpression	GSE13493_CD4INTCD8POS_VS_CD8POS_THYMOCYTE_DN	RNF185 PLEKHA6 EML3 ZNF503 RABL6 ARFGAP2 CABP4 PRRC2B	7.20e-06	198	131	8	M3317
Coexpression	GSE15324_NAIVE_VS_ACTIVATED_ELF4_KO_CD8_TCELL_UP	TNIK GBF1 PPP4R3A KMT2D PLCB2 OSBP2 SIPA1L2 TREML2	7.75e-06	200	131	8	M3526
Coexpression	GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP	HNF1A MXRA8 GPRIN3 PLEKHA6 RREB1 PLCB2 FOXH1	2.81e-05	174	131	7	M8120
Coexpression	GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_DN	SP1 PCLO DENND2B PPP4R3A CELSR3 NUMB MBD5	6.00e-05	196	131	7	M5791
Coexpression	GSE40655_FOXO1_KO_VS_WT_NTREG_UP	SP1 FYCO1 KMT2D DDX46 SEC24C SNAPC4 PRRC2B	6.81e-05	200	131	7	M9439
Coexpression	GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDC_DN	SECISBP2L MUC13 KHDC4 DENND2B PTPRE NUMB PCNX1	6.81e-05	200	131	7	M3779
Coexpression	HARALAMBIEVA_PBMC_FLUARIX_AGE_50_74YO_CORR_WITH_28D_MEM_B_CELL_RESPONSE_AT_0DY_NEGATIVE	NRIP1 ARID3A NUP58 RREB1 DENND1A ZNF503 POM121 MICAL2 PEAK1 RIC1	6.91e-05	435	131	10	M41115
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	TNIK HDAC4 PBX4 GPRIN3 SF1 ESYT2 PCNX1 MAML2	1.11e-07	192	132	8	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VWA5B2 SLC6A17 PCLO RNF183 KCNJ3 SPHKAP WNK2	1.41e-06	186	132	7	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE TNIK KLHL29 ZNF462 SHANK2 MAML2 TNS3	1.51e-06	188	132	7	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	MS-CD4-CD4_Treg\|MS / Condition, Cell_class and T cell subcluster	LAIR2 ZNF835 ZNF462 NUDT11 OSBP2 SNAPC4	4.03e-06	141	132	6	df257dd4dcc45c1ace57340798e150a6e932531d
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	PDXDC1 GPRIN3 SF1 PCNX1 MAML2 IGSF1	7.21e-06	156	132	6	1545169694f686d28648a68b552c2ae606599d66
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SP1 TEDC2 PRAG1 MAML2 SIPA1L2 MBD5	7.75e-06	158	132	6	1d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VGLL3 MXRA8 MICAL2 SKOR1 OSBP2 HS3ST3A1	1.06e-05	167	132	6	805129f887078340b260aa136b0ba19f2bd6ea03
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VGLL3 MXRA8 MICAL2 SKOR1 OSBP2 HS3ST3A1	1.06e-05	167	132	6	31cf8bf2eb523f6e7e319620648ff37fc09e2601
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VGLL3 MXRA8 MICAL2 SKOR1 OSBP2 HS3ST3A1	1.06e-05	167	132	6	3acb18428d1d33ad430c2fd031b1a91baee3c01d
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Adult / Lineage, Cell type, age group and donor	SLC6A17 RNF183 GPRIN1 KCNJ3 SPHKAP SCN5A	1.39e-05	175	132	6	4db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231\|Adult / Lineage, Cell type, age group and donor	SLC6A17 RNF183 GPRIN1 KCNJ3 SPHKAP SCN5A	1.39e-05	175	132	6	8d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SECISBP2L NRIP1 PCLO LAIR2 ZNF503 MBD5	1.48e-05	177	132	6	946803293a7955116c80f403e99e4093e798ca3f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC4 BLNK MUC19 KIAA1549 GPRIN3 KCNJ3	1.58e-05	179	132	6	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	VWA5B2 SLC6A17 PCLO RNF183 KCNJ3 SPHKAP	1.73e-05	182	132	6	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TNIK KIAA1549 DENND1A KLHL29 ZNF462 NUMB	2.02e-05	187	132	6	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VWA5B2 SLC6A17 PCLO RNF183 KCNJ3 SPHKAP	2.08e-05	188	132	6	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLNK RREB1 PLCB2 BIN2 MAML2 TNS3	2.14e-05	189	132	6	389ccb68acb82893709f256315111470cf4beed3
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE KLHL29 ZNF462 KCNJ3 MAML2 TNS3	2.14e-05	189	132	6	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLNK RREB1 PLCB2 BIN2 MAML2 TNS3	2.14e-05	189	132	6	58465b9407fbce91cca8f199950d6e0054c38fbc
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 PCLO GPRIN1 SPHKAP SKOR1 PRKCE	2.14e-05	189	132	6	f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	BLNK RREB1 PLCB2 BIN2 MAML2 TNS3	2.14e-05	189	132	6	7ac78441a15a82218deaafd47accff2ea5c8de20
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	GPRIN3 GPRIN1 SHANK2 CELSR3 KCNJ3 SPHKAP	2.34e-05	192	132	6	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D175\|Adult / Lineage, Cell type, age group and donor	ARHGAP17 RREB1 DENND1A EHBP1L1 SIPA1L2 TNS3	2.34e-05	192	132	6	733491e932350e3c216a626cc49c3cd3fe970a82
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PLEKHA6 DENND1A PRKCE PCNX1 MAML2 TNS3	2.41e-05	193	132	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA5B2 SLC6A17 GPRIN1 SHANK2 KCNJ3 SPHKAP	2.41e-05	193	132	6	461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA5B2 SLC6A17 GPRIN1 SHANK2 KCNJ3 SPHKAP	2.41e-05	193	132	6	0dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 PCLO GPRIN1 SPHKAP SKOR1 PRKCE	2.41e-05	193	132	6	5fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VWA5B2 TMPRSS13 SLC6A17 CELSR3 KCNJ3 SPHKAP	2.63e-05	196	132	6	95544097577f20ed7f4144bd940471cde0617554
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SECISBP2L TNIK CECR2 SHANK2 MICAL2 FHDC1	2.78e-05	198	132	6	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	10x5'v1-week_12-13-Hematopoietic-erythroid-late_erythroid\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PRR5 MICAL2 HPS1 OSBP2 RAD23A	6.99e-05	144	132	5	ca365380ccf5e60d2e3f6272059ff0531759612d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK LAIR2 PBX4 GPRIN3 PLEKHA6	1.25e-04	163	132	5	4dfd408aa700e307478ee35f6b902f68719d8d9e
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRR5 PMEL EML3 CABP4 SIPA1L2	1.29e-04	164	132	5	b175258fb0885afd84d4a414c0ae441f880e8469
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-B_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRR5 PMEL EML3 CABP4 SIPA1L2	1.29e-04	164	132	5	875d922eec7e3df0998ddf0c8c4dee2dcd5b23ca
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRR5 PMEL EML3 CABP4 SIPA1L2	1.29e-04	164	132	5	8bcfc93220d7c99dddb32b7fa7fb9aec2a1c63fa
ToppCell	wk_20-22-Hematologic-Myeloid-GMP\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	HDAC4 RREB1 DENND1A CELSR3 CABP4	1.36e-04	166	132	5	d96e88e73a40205f32cebd7e54ca1ff09ee1e7e8
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FOXE1 TNIK GPRIN3 PCNX1 WNK2	1.40e-04	167	132	5	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-4\|TCGA-Liver / Sample_Type by Project: Shred V9	ARID3A IGSF1 ARHGEF2 TAF5 WNK2	1.48e-04	169	132	5	0a3ba6b5d6cff9d3d7f56046063cfc3a37ae1156
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VWA5B2 RNF183 KCNJ3 SCN5A WNK2	1.48e-04	169	132	5	96a2aec9acf8a6f966973c035e5ade456cf47772
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VWA5B2 RNF183 KCNJ3 SPHKAP WNK2	1.48e-04	169	132	5	b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCell	facs-Lung-24m-Epithelial-airway_epithelial-club_cell-club_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CHIA CEL TMPRSS13 RNF183 OSBP2	1.57e-04	171	132	5	8ed98f223143bd81d9819e9a420eb9cc81ee6c53
ToppCell	facs-Lung-24m-Epithelial-airway_epithelial-club_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CHIA CEL TMPRSS13 RNF183 OSBP2	1.57e-04	171	132	5	bd339e482f09a3fa04b086029b94f45205b8a6c5
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ARID3A BLNK NFKBIE PLCB2 TREML2	1.61e-04	172	132	5	76c06a968d3333441eed103abef1e636a1c3e7a1
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO KIAA1549 SCAF1 SPHKAP PCNX1	1.70e-04	174	132	5	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VGLL3 MXRA8 MAML2 PEAK1 HS3ST3A1	1.75e-04	175	132	5	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA8 GPRIN3 NUDT10 PEAK1 HS3ST3A1	1.75e-04	175	132	5	1b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCell	droplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT3 BLNK CABP4 OSBP2	1.76e-04	94	132	4	d25f096626af873f724a8cd6454ed56e33fd9854
ToppCell	droplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT3 BLNK CABP4 OSBP2	1.76e-04	94	132	4	2fb80a08f823295fa4c3e6494bf020e5b4052f0f
ToppCell	droplet-Lung-LUNG-30m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHIA CECR2 CDHR5 FHDC1 IGSF1	1.79e-04	176	132	5	5201f003192c033655ba47f0faf8c47a96eae03d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE KLHL29 ZNF462 MAML2 TNS3	1.79e-04	176	132	5	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE KLHL29 SHANK2 MAML2 TNS3	1.84e-04	177	132	5	da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Enterocyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARID3A CEL CDHR5 VWA1 MUC13	1.84e-04	177	132	5	1f5b6498364b2017c4d49cd337d6e91c8e4f840d
ToppCell	PBMC-Severe-cDC_11\|Severe / Compartment, Disease Groups and Clusters	CECR2 PLEKHA6 RTN2 KLHL29 NUDT11	1.89e-04	178	132	5	0667abc05eb2254710b9c648c65b7cfdfe7831b7
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA5B2 PCLO GPRIN1 CELSR3 GSDMA	1.89e-04	178	132	5	30ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	TRHDE PCLO PLEKHA6 PRKCE IGSF1	1.94e-04	179	132	5	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	367C-Epithelial_cells-Epithelial-B_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CECR2 SKOR1 OSBP2 BIN2	1.99e-04	97	132	4	eab10b1af9cd0ce373cd4d0316e0d7b218630584
ToppCell	367C-Epithelial_cells-Epithelial-B_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CECR2 SKOR1 OSBP2 BIN2	1.99e-04	97	132	4	04f571708f2487b0dbd70ee507de6bf75be5f5d9
ToppCell	droplet-Lung-LUNG-30m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHIA CECR2 CDHR5 KLHL29 FHDC1	2.04e-04	181	132	5	cadb18fc73031eb9f779599e15cd7861337fee78
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA8 GPRIN3 NUDT10 PEAK1 HS3ST3A1	2.04e-04	181	132	5	a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK MXRA8 KHDC4 ZNF503 MAML2	2.04e-04	181	132	5	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	droplet-Lung-LUNG-30m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHIA CECR2 CDHR5 KLHL29 FHDC1	2.04e-04	181	132	5	85bec4d3f255f4c61c790325eeb50ad38f709ef2
ToppCell	Control-Classical_Monocyte-cMono_4\|Control / Disease condition and Cell class	NRIP1 GPRIN3 PTPRE MAP1S PCNX1	2.04e-04	181	132	5	f3e1d8fe5cf1eba19e51c3680a55306cae687fe9
ToppCell	Pericytes-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CEL MXRA8 MEIS3P1 NUDT11 HS3ST3A1	2.04e-04	181	132	5	35c470988a93381eefa300831aabb813fa1b90bd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA8 GPRIN3 NUDT10 PEAK1 HS3ST3A1	2.04e-04	181	132	5	526e858a848470b6d2d5248788004d9735ed3add
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE KLHL29 KCNJ3 MAML2 TNS3	2.04e-04	181	132	5	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE KLHL29 ZNF462 MAML2 TNS3	2.09e-04	182	132	5	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRHDE PCLO PLEKHA6 SHANK2 KCNJ3	2.09e-04	182	132	5	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRHDE KLHL29 ZNF462 MAML2 TNS3	2.15e-04	183	132	5	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	COVID-19_Severe-RBC\|COVID-19_Severe / disease group, cell group and cell class	MICAL2 HPS1 OSBP2 FHDC1 RAD23A	2.20e-04	184	132	5	bb58244194ffb5558fbe85c5f856888210dcb1e8
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SECISBP2L CECR2 GPRIN3 SHANK2 SPHKAP	2.26e-04	185	132	5	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SALL3 CECR2 ZNF462 MAML2 TNS3	2.26e-04	185	132	5	2e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCell	Control-Myeloid-Macrophage_Alveolar\|World / Disease state, Lineage and Cell class	TRHDE NRIP1 GPRIN3 PRAG1 KLHL29	2.26e-04	185	132	5	85cb81759589a26d83676cffbf2bc37399683c10
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SALL3 CECR2 ZNF462 MAML2 TNS3	2.26e-04	185	132	5	7aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CECR2 KIAA1549 KMT2D PHLPP1 WNK2	2.26e-04	185	132	5	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA5B2 PCLO NUDT11 KCNJ3 GSDMA	2.26e-04	185	132	5	2a8104f610fa5ce618f8105521616722462a0d42
ToppCell	wk_20-22-Hematologic-Meg-ery-Definitive_reticulocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PRR5 MICAL2 OSBP2 FHDC1 RAD23A	2.26e-04	185	132	5	4a2c85e292d4cbce80e92992ded5d66a3aa446ee
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SECISBP2L SP1 HDAC4 PDPK1 PRRC2B	2.32e-04	186	132	5	74c238759c5d3fd39127ec0060d0c2cb16b326d4
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ3 SCN5A OSBP2 IGSF1 WNK2	2.32e-04	186	132	5	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ3 SCN5A OSBP2 IGSF1 WNK2	2.32e-04	186	132	5	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	PCW_07-8.5-Hematologic_ErythroMegGranulo\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	EHBP1L1 MICAL2 OSBP2 BIN2 TREML2	2.32e-04	186	132	5	294839944266407c40ef86e1d3e0fce4652b70ff
ToppCell	PCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-erythro\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MICAL2 HPS1 OSBP2 FHDC1 TREML2	2.32e-04	186	132	5	34ed60e846fd83fab3e28dc9e278bcc4b092a9f0
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	TNIK SP1 MED1 DDX46 SPTY2D1	2.32e-04	186	132	5	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_reticulocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PRR5 MICAL2 OSBP2 FHDC1 TREML2	2.32e-04	186	132	5	bf8ca7135c05d772aa3f5960b419a13aef3936ae
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNIK ARID3A LAIR2 ZNF462 KCNJ3	2.37e-04	187	132	5	b426a67b5669019115b58295ce7d304beeb75825
ToppCell	human_hepatoblastoma-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	R3HDM2 SHANK2 MBD5 WNK2 TNS3	2.37e-04	187	132	5	f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRHDE PCLO PLEKHA6 SHANK2 KCNJ3	2.37e-04	187	132	5	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	Tuft-tuft-2\|World / Class top	FOXE1 ADGRB2 PLCB2 ARHGEF2 WNK2	2.37e-04	187	132	5	4ec6eee866619dfe13c84f5d2e812bb380d37139
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	SECISBP2L SP1 HDAC4 PDPK1 MAML2	2.37e-04	187	132	5	816d37a70f7ec382a268fe828b3dfe737a36a4bf
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 PLEKHA6 GPRIN1 SPHKAP SKOR1	2.43e-04	188	132	5	1efbc99bcd6542e5d9fa91edb7c4295167914786
ToppCell	COVID-19-kidney-DCT\|kidney / Disease (COVID-19 only), tissue and cell type	SALL3 CECR2 BLNK GPRIN3 DENND2B	2.43e-04	188	132	5	df1fd0819d301679f3c9ea404e942e39095912eb
ToppCell	facs-Heart-RA-24m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ3 SCN5A OSBP2 IGSF1 WNK2	2.49e-04	189	132	5	e4efbb0733b382f4c855f6653dcddf36e0f8df28
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ3 SCN5A OSBP2 IGSF1 WNK2	2.49e-04	189	132	5	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	Non-neuronal-Non-dividing-OPC-OPC\|World / Primary Cells by Cluster	SALL3 PTPRE MAML2 PEAK1 TNS3	2.49e-04	189	132	5	ddf5be73912570c32c50f4ac2902da9b590526f8
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	VGLL3 MXRA8 PLEKHA6 PEAK1 TNS3	2.49e-04	189	132	5	dc5164591dea45b420798b94dda211be03daa70c
ToppCell	IPF-Epithelial-Aberrant_Basaloid\|Epithelial / Disease state, Lineage and Cell class	VGLL3 MXRA8 PRAG1 PTPRE MICAL2	2.49e-04	189	132	5	4178be3292ff4a8a1d8098f638d4b8d15164d2c6
ToppCell	Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	VGLL3 GPRIN3 EHBP1L1 PLCB2 SIPA1L2	2.49e-04	189	132	5	c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ3 SCN5A OSBP2 IGSF1 WNK2	2.49e-04	189	132	5	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	Non-neuronal-Non-dividing-OPC\|World / Primary Cells by Cluster	SALL3 PTPRE MAML2 PEAK1 TNS3	2.49e-04	189	132	5	13848a031ab896b4b24c8319e4745b9b17ff9cfd
ToppCell	Non-neuronal-Non-dividing-OPC-OPC-30\|World / Primary Cells by Cluster	SALL3 PTPRE MAML2 PEAK1 TNS3	2.49e-04	189	132	5	313d165fad541ec6e8dd524b88856e2c93eeb681
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SECISBP2L CECR2 PRAG1 SHANK2 ARHGEF2	2.55e-04	190	132	5	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	VGLL3 DENND2B MICAL2 MAML2 PEAK1	2.55e-04	190	132	5	1121eb607a984c59fbffe7220837fc178745aa55
Drug	rosiglitazone; Down 200; 10uM; PC3; HT_HG-U133A	BICRA ADGRB2 MLLT10 RTN2 PPP4R3A PHF1 MICAL2 PCNX1	1.30e-05	187	131	8	4457_DN
Drug	beta-caryophyllene oxide	CHIA CEL FARP2	1.52e-05	9	131	3	CID000014350
Drug	Hyoscyamine (L) [101-31-5]; Down 200; 13.8uM; MCF7; HT_HG-U133A	SECISBP2L BICRA PRR5 EML3 MICAL2 KCNJ3 IGSF1 ARHGEF2	1.58e-05	192	131	8	2271_DN
Drug	Sulpiride [15676-16-1]; Up 200; 11.8uM; PC3; HG-U133A	TRHDE TEDC2 MAP3K12 NUDT11 PHLPP1 NUMB SNAPC4 PRRC2B	1.90e-05	197	131	8	1887_UP
Drug	Benoxinate hydrochloride [5987-82-6]; Down 200; 11.6uM; PC3; HT_HG-U133A	VGLL3 TEDC2 PCLO MLLT10 DENND2B EML3 SHANK2 PCNX1	1.90e-05	197	131	8	3996_DN
Drug	Cromolyn disodium salt [15826-37-6]; Down 200; 7.8uM; MCF7; HT_HG-U133A	SP1 PDPK1 TEDC2 PRR5 DENND1A EML3 AGFG2 PCNX1	1.97e-05	198	131	8	3475_DN
Drug	Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; MCF7; HT_HG-U133A	PLEKHA6 MLLT10 DENND2B EML3 FARP2 EHBP1L1 KCNJ3 ARHGEF2	1.97e-05	198	131	8	3883_DN
Drug	Hydroxytacrine maleate (R,S) [118909-22-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A	SECISBP2L PDPK1 MLLT10 MED1 SF1 EHBP1L1 PHLPP1 PCNX1	1.97e-05	198	131	8	3292_DN
Drug	chi2 6	CHIA CHIT1	3.29e-05	2	131	2	CID000063339
Drug	adenosine 5'-tetraphosphate	NUDT11 NUDT10	3.29e-05	2	131	2	ctd:C017991
Drug	laminarihexaose	CHIA CHIT1	3.29e-05	2	131	2	CID000169096
Drug	diadenosine 5',5''''-P1,P6-hexaphosphate	NUDT11 NUDT10	3.29e-05	2	131	2	ctd:C070070
Drug	CID5289292	CHIA CHIT1	3.29e-05	2	131	2	CID005289292
Drug	glucoallosamidin B	CHIA CHIT1	3.29e-05	2	131	2	CID000195827
Drug	adenosine 5'-pentaphosphate	NUDT11 NUDT10	3.29e-05	2	131	2	ctd:C048567
Drug	GlcNAc)8	CHIA CHIT1	3.29e-05	2	131	2	CID000192495
Disease	myeloid white cell count	ATF7 NRIP1 HNF1A CEL SLC6A17 UBQLN4 R3HDM2 RREB1 DENND2B KLHL29 MICAL2 GSDMA PRKCE PLCB2 TNS3 TREML2	3.51e-06	937	129	16	EFO_0007988
Disease	Chromosome 2q37 deletion syndrome	HDAC4 FARP2	1.13e-04	4	129	2	C2931817
Disease	red blood cell density measurement	PDXDC1 SP1 HNF1A R3HDM2 RREB1 DENND2B PPP4R3A FARP2 ZNF462 UBR5 PRKCE MAML2 TNS3	1.32e-04	880	129	13	EFO_0007978
Disease	lymphocyte percentage of leukocytes	TNIK ATF7 HNF1A GBF1 CEL CECR2 PBX4 ARID1A UBR5 GSDMA SNAPC4	1.69e-04	665	129	11	EFO_0007993
Disease	serum albumin measurement	PDXDC1 HNF1A PILRB PBX4 R3HDM2 MLLT10 FARP2 SCAF1 EHBP1L1 SPTY2D1	2.85e-04	592	129	10	EFO_0004535
Disease	neutrophil count	ATF7 SP1 HNF1A CEL SLC6A17 RNF185 UBQLN4 RNF183 RREB1 ARID1A DENND2B FARP2 MICAL2 GSDMA PLCB2 TNS3	3.58e-04	1382	129	16	EFO_0004833
Disease	glomerular filtration rate, renal transplant outcome measurement	TNIK HDAC4 MICAL2	4.82e-04	35	129	3	EFO_0005199, EFO_0005208
Disease	hematocrit	NRIP1 HNF1A UBQLN4 R3HDM2 PLEKHA6 RREB1 DENND2B KLHL29 ZNF462 AGFG2 NUMB PRKCE MAML2	5.00e-04	1011	129	13	EFO_0004348
Disease	reaction time measurement	TNIK MUC19 CEP192 ARFGAP2 KMT2D POM121 KCNJ3 GSDMA PRKCE FOXH1	6.49e-04	658	129	10	EFO_0008393
Disease	influenza A severity measurement	PRAG1 MAML2	6.69e-04	9	129	2	EFO_0007743
Disease	22q11 partial monosomy syndrome	RREB1 SEC24C	6.69e-04	9	129	2	C3266101
Disease	level of Sterol ester (27:1/16:1) in blood serum	HNF1A DENND1A	6.69e-04	9	129	2	OBA_2045190
Disease	supraventricular ectopy	SCN5A TREML2	6.69e-04	9	129	2	EFO_0009277
Disease	thyroid gland papillary carcinoma (is_implicated_in)	FOXE1 KMT2D	8.34e-04	10	129	2	DOID:3969 (is_implicated_in)
Disease	Asymmetric crying face association	RREB1 SEC24C	8.34e-04	10	129	2	C0431406
Disease	22q11 Deletion Syndrome	RREB1 SEC24C	8.34e-04	10	129	2	C2936346
Disease	gastric adenocarcinoma (is_implicated_in)	KMT2D UBR5	1.02e-03	11	129	2	DOID:3717 (is_implicated_in)
Disease	Congenital Hypothyroidism	FOXE1 IGSF1	1.43e-03	13	129	2	C0010308
Disease	uric acid measurement	TNIK HNF1A CEL ARHGAP17 PLEKHA6 RREB1 ARID1A FARP2 PRRC2B	1.48e-03	610	129	9	EFO_0004761
Disease	Maturity onset diabetes mellitus in young	HNF1A CEL	1.67e-03	14	129	2	C0342276
Disease	alkaline phosphatase measurement	ATF7 HNF1A CEL PBX4 RREB1 PRAG1 DENND2B FARP2 POM121 CASKIN1 GSDMA RIC1	1.69e-03	1015	129	12	EFO_0004533
Disease	African Burkitt's lymphoma	SALL3 ARID1A	1.92e-03	15	129	2	C0343640
Disease	Burkitt Leukemia	SALL3 ARID1A	1.92e-03	15	129	2	C4721444
Disease	monocyte count	ATF7 NRIP1 CECR2 PBX4 R3HDM2 PLEKHA6 MLLT10 RREB1 DENND2B NFKBIE PRKCE MBD5 TNS3 TREML2	1.94e-03	1320	129	14	EFO_0005091
Disease	urate measurement	HNF1A UBQLN4 ARHGAP17 R3HDM2 RREB1 ARID1A SF1 FARP2 SHANK2 MBD5 PRRC2B	1.95e-03	895	129	11	EFO_0004531
Disease	aspartate aminotransferase measurement	HNF1A CEL PDPK1 MUC19 PBX4 GPRIN3 R3HDM2 FYCO1 MLLT10 PRAG1 WNK2	2.10e-03	904	129	11	EFO_0004736
Disease	DiGeorge Syndrome	RREB1 SEC24C	2.19e-03	16	129	2	C0012236
Disease	CONOTRUNCAL ANOMALY FACE SYNDROME	RREB1 SEC24C	2.19e-03	16	129	2	C0795907
Disease	T-Cell Lymphoma	ARID1A KMT2D	2.19e-03	16	129	2	C0079772
Disease	Shprintzen syndrome	RREB1 SEC24C	2.19e-03	16	129	2	C0220704
Disease	serum gamma-glutamyl transferase measurement	TNIK HNF1A BICRA RREB1 ARID1A DENND2B FARP2 POM121 MAP1S ARHGEF2 SIPA1L2	2.29e-03	914	129	11	EFO_0004532
Disease	C-reactive protein measurement	HNF1A CEL PBX4 R3HDM2 CEP192 MLLT10 RREB1 PRAG1 EML3 FARP2 SPHKAP NUMB SNAPC4	2.45e-03	1206	129	13	EFO_0004458
Disease	brain measurement, neuroimaging measurement	VWA5B2 PDXDC1 TNIK MLLT10 RREB1 PPP4R3A ZNF462 WNK2	2.95e-03	550	129	8	EFO_0004346, EFO_0004464
Disease	level of Sterol ester (27:1/20:3) in blood serum	PDXDC1 HNF1A	3.09e-03	19	129	2	OBA_2045199
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	PDXDC1 HNF1A PBX4 R3HDM2 ARID1A	3.10e-03	224	129	5	EFO_0004530, EFO_0008317
Disease	skin pigmentation	PLEKHA6 OSBP2 MAML2	3.47e-03	69	129	3	EFO_0003784
Disease	neuroticism measurement, cognitive function measurement	TRHDE PCLO R3HDM2 MLLT10 ARID1A DENND1A KLHL29 SCAF1	3.51e-03	566	129	8	EFO_0007660, EFO_0008354
Disease	blood urea nitrogen measurement	HNF1A GPRIN3 R3HDM2 PLEKHA6 RREB1 ZNF462 MBD5	3.81e-03	452	129	7	EFO_0004741
Disease	phospholipids in large HDL measurement	PDXDC1 HNF1A ARID1A	4.06e-03	73	129	3	EFO_0022190
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	PDXDC1 HNF1A MLLT10 ARID1A	4.12e-03	148	129	4	C0279702
Disease	non-high density lipoprotein cholesterol measurement	SP1 HNF1A CEL R3HDM2 ARID1A ESYT2 POM121 PRKCE SPTY2D1	4.19e-03	713	129	9	EFO_0005689
Disease	creatinine measurement	ATF7 HNF1A CEL PBX4 R3HDM2 MED1 RREB1 ARID1A CELSR3 NUMB MBD5	4.35e-03	995	129	11	EFO_0004518

Protein segments in the cluster

Peptide	Gene	Start	Entry
AGGVASPGTTSAQPP	TRHDE	111	Q9UKU6
SSRQPAAGAPSPGDS	AHRR	91	A9YTQ3
PGEAGAGSTTTTSPG	ADGRB2	226	O60241
SGSPGPGGSNTAPST	ESYT2	691	A0FGR8
PGGSNTAPSTPVIGG	ESYT2	696	A0FGR8
GTTNTATTAGPAPGG	BAG6	576	P46379
PLEPDSGGNTSPGVT	ARHGEF2	686	Q92974
PGSSPSDPTDTGNFG	GSDMA	66	Q96QA5
PSNTGIGAPTSGAGP	CHIA	276	Q9BZP6
GSAPSQAGPGSAPSS	ARMC5	81	Q96C12
PSGTQQPAPSTESSG	ARFGAP2	171	Q8N6H7
GPPVNSSGSISPSGH	ATF7	236	P17544
EPSQGPSTTSSGGGT	CDHR5	486	Q9HBB8
STPGGPPGAENSTSH	CDHR5	516	Q9HBB8
PSGGTAQTPEPGTSQ	CDHR5	566	Q9HBB8
TPGGGTAQTPEAGTS	CDHR5	596	Q9HBB8
TTPGGGTAQTPEPGT	CDHR5	626	Q9HBB8
GDSGAPPVTPTGDSE	CEL	696	P19835
GSGSTKPGTPGNSPS	DENND2B	356	P78524
GNIPSSPTASGGGSP	BIN2	431	Q9UBW5
PPSTDPGLTGGTVSQ	CECR2	1121	Q9BXF3
GGSPTNGNSMAPSSP	NUDT10	146	Q8NFP7
GTSPSVGFLQPPGSE	R3HDM2	661	Q9Y2K5
AGQGTSAPPEASPTA	RAD23A	81	P54725
AVSTGSSSPGTPQPA	RABL6	306	Q3YEC7
GSGESETPPSTPTAQ	RIC1	986	Q4ADV7
GSPGSPGSVPKNTSQ	PPP4R3A	776	Q6IN85
SSQPASTAGVGPGVP	KIAA1549	1701	Q9HCM3
AAGGGTPQPTATPTL	ARID1A	281	O14497
VGAPATGSGTPGPFT	CHIT1	281	Q13231
GDSQVSSNPTSSPPG	FHDC1	816	Q9C0D6
QGSSSSGPSAPPEEI	CASKIN1	361	Q8WXD9
ETTTTSGPPDPGASQ	PTPRE	31	P23469
PGSGPSSPNNSSGSV	HDAC4	296	P56524
GGEAGPDASPTVTTP	MAP1S	661	Q66K74
SQGASPTGSPDAGVS	MAGEB6	106	Q8N7X4
APQSSPVPAGTGNSG	FOXH1	186	O75593
GSGTSQGEPSPALSP	FYCO1	1241	Q9BQS8
GAESPQPASGSSPSE	PRKCE	326	Q02156
STSAPASGPSDGSPQ	NFKBIE	171	O00221
SAGSSSVPSPGQPGS	PCLO	4656	Q9Y6V0
PGQGSGTGLHPPVTS	PCNX1	2081	Q96RV3
TTGPTAGVTGTNGPS	MUC19	3226	Q7Z5P9
GTAQGFGPAEPSPTS	PEAK1	1531	Q9H792
AQGAGVTLPPTPSGS	PDXDC1	681	Q6P996
YPEGTPNGGSTTLPS	NBDY	36	A0A0U1RRE5
TAADSQQPPGGSSPS	EHBP1L1	1326	Q8N3D4
AFSSQPTGPEPGLSG	NRIP1	686	P48552
PGEPASLGPTFTNTG	HNF1A	416	P20823
GSGAGSTVAEAPPGT	HS3ST3A1	126	Q9Y663
GGSPTNGNSMAPSSP	NUDT11	146	Q96G61
SGSDGDSVPVSPQPA	EN1	41	Q05925
PDQKGSGTGGTTTPP	MEIOSIN	211	C9JSJ3
PGSESSSGVGAGPFT	OSBP2	106	Q969R2
GGTATPTFGLNTPAP	POM121B	761	A6NF01
PTFGLNTPAPGVGTS	POM121B	766	A6NF01
SEYSPGLTQGPSGSP	MAML2	366	Q8IZL2
GGTATPTFGLNTPAP	POM121	1176	Q96HA1
PTFGLNTPAPGVGTS	POM121	1181	Q96HA1
PATASPAGDPGSINS	PBX4	356	Q9BYU1
EGEPGTPANSPSSTS	IGSF1	1311	Q8N6C5
GGNPTVDGPLPSFSS	BLNK	316	Q8WV28
GSSGEQTGPEAPGSS	CABP4	56	P57796
EGSAPGSTSPDSPGG	MAP3K12	646	Q12852
TSPGGGTNATPVVPS	MBD5	126	Q9P267
VPSGSSPGSQSDAEP	CEP192	71	Q8TEP8
QPLSPGPGAAGTSSD	DENND1A	766	Q8TEH3
QPGSPGYSTATEPGS	GBF1	311	Q92538
PAAPGGEVTSSGGSP	KHDC4	31	Q7Z7F0
SSLQGSGTPAPPGDS	EML3	51	Q32P44
AAPGTSSVPAPTAGN	DDX46	831	Q7L014
GALSSGVPGSGNSSP	CELSR3	156	Q9NYQ7
GVPGSGNSSPLPSDF	CELSR3	161	Q9NYQ7
PESSGKTNPVSSGPG	GPRIN1	481	Q7Z2K8
SGGTESAANPTPSPI	GPRIN3	571	Q6ZVF9
SGAVAGGPDTPSAQP	FARP2	446	O94887
FTPAPSPGDQSSGST	HPS1	301	Q92902
GAASAPTGTPSGQPL	BICRA	311	Q9NZM4
APSQASSFTPPASGG	SEC24C	206	P53992
ESGASTPGGPAEPSA	SALL3	296	Q9BXA9
TGNGGSTIGSSPTPP	MED1	611	Q15648
GPDSPDTEPGSSAGT	LAIR2	126	Q6ISS4
TSVSGNAPDGSSPPQ	MICAL2	1291	O94851
PATGPQPSLGVSFGT	NUP58	476	Q9BVL2
TPGPSSGGLASQSGD	MEIS3P1	116	A6NDR6
VGSSVAPGNTAPSPS	NUMB	226	P49757
PPTGDGALTSFPSGQ	PHF1	341	O43189
QLSPGSGTPQAGTPS	RTN2	206	O75298
PSQTSPELPSEGGAG	SYT3	181	Q9BQG1
PDPPGTGASGATVVS	TAF5	161	Q15542
GEQPTGPPSATSSGA	SKOR1	691	P84550
GPPSATSSGADGPAN	SKOR1	696	P84550
QAGVPDPGTGASSGT	SOHLH1	141	Q5JUK2
QSESTEAPASGPPTG	SPHKAP	1586	Q2M3C7
QAPTSGPDAPFTTGV	TREML2	151	Q5T2D2
GQTGPPPDTASATVS	RNF183	126	Q96D59
GTTASAPPHSPGQAG	TEDC2	116	Q7L2K0
PASPPAGGSSGGVET	FOXE1	306	O00358
EPPPQSSRAESSSGG	ARHGAP17	541	Q68EM7
PGGQSSSGTSQHPPS	ARHGAP17	651	Q68EM7
SDPPGQGPTGTFRSS	PRR5	296	P85299
TQTESSTPPGIPGGS	PDPK1	31	O15530
SAQGQPSPGTSAPGH	SCN5A	571	Q14524
PSNQSSSSDPGPGGS	SIPA1L2	1121	Q9P2F8
PVSQGSPASSGIGSP	SECISBP2L	646	Q93073
SSSTGGGGQESQPSP	SP1	46	P08047
NGAGPELSTGPSPGS	TNS3	676	Q68CZ2
TPGQAPTAEPSGTTS	PMEL	336	P40967
PGSSSSSAPGQPSTG	SPTY2D1	371	Q68D10
PAVPSASSGTAGPGN	SHANK2	1186	Q9UPX8
PGSGDRVSGSSQSPP	AKAP3	196	O75969
SPFPQGSFSGTPGSV	MLLT10	346	P55197
PAGSSQGTPFGATPL	AGFG2	291	O95081
SGGQAGPAGLSTPST	ARID3A	571	Q99856
SGPESGAGPAPTQLA	VWA1	311	Q6PCB0
SGSQGSPTKPGSNEP	PLEKHA6	711	Q9Y2H5
PSSQPSSQGGSQPGS	TNIK	736	Q9UKE5
SAGASPAQASPAGTP	TMPRSS13	16	Q9BYE2
PTTEDNQSSGPPTGT	MUC13	146	Q9H3R2
PEAASPTEQGPAGTS	RREB1	1136	Q92766
FEPTGSNPSSSAGTP	SCAF1	251	Q9H7N4
SPSLPEQSSPGGAGS	PRRC2B	1866	Q5JSZ5
PSASASPENSSAGGP	RNF185	6	Q96GF1
PAFLQPGGSTGSGPS	PILRB	16	Q9UKJ0
GSSGGSSIGPQPPSQ	PRAG1	576	Q86YV5
DTGGEAEGSSPPSAP	PLCB2	476	Q00722
AEGSSPPSAPAGEGT	PLCB2	481	Q00722
LSGNSSGPGPGSSPA	ZNF503	36	Q96F45
PGPGSTGSSESPGSQ	VWA5B2	676	Q8N398
TGSSESPGSQGPGSP	VWA5B2	681	Q8N398
APTPDSTPGLSQGGE	ZNF835	506	Q9Y2P0
HGAQAEGSSSGPPVP	ZNF462	131	Q96JM2
EGSSSGPPVPGSLNY	ZNF462	136	Q96JM2
SDSSPGEPFVGGPVS	PHLPP1	321	O60346
GPGSTSPLETSGNPN	SLC6A17	696	Q9H1V8
TEPRGTPGSPSGTQE	SNAPC4	1216	Q5SXM2
PASGTASQAGGPGTP	WNK2	1446	Q9Y3S1
QVTGPPGTFSAADPS	VGLL3	171	A8MV65
SPPTSQAPGSGGEGT	UBQLN4	336	Q9NRR5
PSAGSNAGSTPEAPT	UBQLN4	501	Q9NRR5
GEAPVPASVGSTSGP	SF1	321	Q15637
GTGQGPSTSTIPGPS	UBR5	1056	O95071
SGAPATNGPPTTDSA	KLHL29	276	Q96CT2
PSTPTTPTTEGEGDG	KMT2D	1981	O14686
TTSSSGSGLQPQGPG	KCNJ3	16	P48549
NGSSHSGAPGPDPTL	MXRA8	306	Q9BRK3