Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	CFAP100 ROCK2 SPATA7 FSIP2 ANK3 CLIP2 DCTN6 TACC1 TUBGCP5 CHMP2A CHMP2B CEP63	3.30e-07	720	55	12	GO:0000226
GeneOntologyBiologicalProcess	microtubule-based process	CFAP100 ROCK2 SPATA7 FSIP2 ANK3 CLIP2 DCTN6 TACC1 TUBGCP5 CHMP2A CHMP2B CEP63	1.76e-05	1058	55	12	GO:0007017
GeneOntologyBiologicalProcess	spindle organization	DCTN6 TACC1 TUBGCP5 CHMP2A CHMP2B CEP63	2.85e-05	224	55	6	GO:0007051
GeneOntologyBiologicalProcess	centrosome duplication	ROCK2 CHMP2A CHMP2B CEP63	6.46e-05	81	55	4	GO:0051298
GeneOntologyBiologicalProcess	mitotic cytokinesis	ROCK2 ANK3 CHMP2A CHMP2B	1.20e-04	95	55	4	GO:0000281
GeneOntologyBiologicalProcess	regulation of interferon-alpha production	GBP6 PTPN22 NMBR	1.31e-04	37	55	3	GO:0032647
GeneOntologyBiologicalProcess	negative regulation of bicellular tight junction assembly	ROCK2 IKBKB	1.45e-04	7	55	2	GO:1903347
GeneOntologyBiologicalProcess	interferon-alpha production	GBP6 PTPN22 NMBR	1.65e-04	40	55	3	GO:0032607
GeneOntologyCellularComponent	autophagosome membrane	CALCOCO2 CHMP2A CHMP2B	4.56e-04	57	55	3	GO:0000421
GeneOntologyCellularComponent	amphisome membrane	CHMP2A CHMP2B	5.20e-04	13	55	2	GO:1904930
GeneOntologyCellularComponent	ESCRT III complex	CHMP2A CHMP2B	6.06e-04	14	55	2	GO:0000815
GeneOntologyCellularComponent	amphisome	CHMP2A CHMP2B	6.98e-04	15	55	2	GO:0044753
Domain	Snf7_fam	CHMP2A CHMP2B	5.51e-04	12	55	2	IPR005024
Domain	Snf7	CHMP2A CHMP2B	5.51e-04	12	55	2	PF03357
Domain	DUF4599	SPATA31D4 SPATA31D3	5.51e-04	12	55	2	PF15371
Domain	DUF4599	SPATA31D4 SPATA31D3	5.51e-04	12	55	2	IPR027970
Domain	p53-like_TF_DNA-bd	TP63 STAT4	1.07e-02	53	55	2	IPR008967
Pathway	REACTOME_PYROPTOSIS	TP63 CHMP2A CHMP2B	6.36e-05	27	41	3	M41804
Pubmed	Association of STAT4 rs7574865 and PTPN22 rs2476601 polymorphisms with rheumatoid arthritis and non-systemically reacting antibodies in Egyptian patients.	PTPN22 STAT4	2.46e-06	2	55	2	28424905
Pubmed	Association of PTPN22 rs2476601 and STAT4 rs7574865 polymorphisms with rheumatoid arthritis: A meta-analysis update.	PTPN22 STAT4	2.46e-06	2	55	2	25963842
Pubmed	Association of PTPN22 (rs2476601) and STAT4 (rs7574865) polymorphisms with Rheumatoid Arthritis in the Western Algerian population.	PTPN22 STAT4	2.46e-06	2	55	2	25351936
Pubmed	The ESCRT-III isoforms CHMP2A and CHMP2B display different effects on membranes upon polymerization.	CHMP2A CHMP2B	2.46e-06	2	55	2	33832485
Pubmed	STAT4 rs7574865 G/T and PTPN22 rs2488457 G/C polymorphisms influence the risk of developing juvenile idiopathic arthritis in Han Chinese patients.	PTPN22 STAT4	2.46e-06	2	55	2	25781893
Pubmed	Phosphorylation and stabilization of TAp63gamma by IkappaB kinase-beta.	TP63 IKBKB	2.46e-06	2	55	2	18411264
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	SLC38A1 CEP170 ROCK2 BABAM1 SRP54 TACC1 RUFY1 CHMP2B	2.99e-06	568	55	8	37774976
Pubmed	ROCK-dependent phosphorylation of NUP62 regulates p63 nuclear transport and squamous cell carcinoma proliferation.	ROCK2 TP63	7.36e-06	3	55	2	29217659
Pubmed	Regulation of p53 family member isoform DeltaNp63alpha by the nuclear factor-kappaB targeting kinase IkappaB kinase beta.	TP63 IKBKB	7.36e-06	3	55	2	20145131
Pubmed	Hepatic p63 regulates steatosis via IKKβ/ER stress.	TP63 IKBKB	7.36e-06	3	55	2	28480888
Pubmed	Rbfox2-coordinated alternative splicing of Mef2d and Rock2 controls myoblast fusion during myogenesis.	ROCK2 RBFOX2	7.36e-06	3	55	2	25087874
Pubmed	IκB kinase β (IKKβ) inhibits p63 isoform γ (TAp63γ) transcriptional activity.	TP63 IKBKB	7.36e-06	3	55	2	23589370
Pubmed	Analysis of PTPN22, ZFAT and MYO9B polymorphisms in Turner Syndrome and risk of autoimmune disease.	ZFAT PTPN22	7.36e-06	3	55	2	28627089
Pubmed	Lack of association of PTPN22, STAT4 and TRAF1/C5 gene polymorphisms with cardiovascular risk in rheumatoid arthritis.	PTPN22 STAT4	1.47e-05	4	55	2	20822712
Pubmed	ESCRT-III subunits Snf7-1 and Snf7-2 differentially regulate transmembrane cargos in hESC-derived human neurons.	CHMP2A CHMP2B	1.47e-05	4	55	2	21975012
Pubmed	ESCRT-III CHMP2A and CHMP3 form variable helical polymers in vitro and act synergistically during HIV-1 budding.	CHMP2A CHMP2B	1.47e-05	4	55	2	23051622
Pubmed	Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci.	PTPN22 STAT4	2.45e-05	5	55	2	19741008
Pubmed	ESCRT-III recognition by VPS4 ATPases.	CHMP2A CHMP2B	3.67e-05	6	55	2	17928862
Pubmed	Evaluation of the rheumatoid arthritis susceptibility loci HLA-DRB1, PTPN22, OLIG3/TNFAIP3, STAT4 and TRAF1/C5 in an inception cohort.	PTPN22 STAT4	5.13e-05	7	55	2	20353580
Pubmed	Ab initio protein modelling reveals novel human MIT domains.	CHMP2A CHMP2B	6.83e-05	8	55	2	19302785
Pubmed	The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria.	CALCOCO2 IKBKB	6.83e-05	8	55	2	19820708
Pubmed	CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins.	CHMP2A CHMP2B	6.83e-05	8	55	2	11559748
Pubmed	ESCRT requirements for EIAV budding.	CHMP2A CHMP2B	6.83e-05	8	55	2	24107264
Pubmed	Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases.	ROCK2 IKBKB	6.83e-05	8	55	2	25816133
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	CEP170 DCTN6 TUBGCP5 CEP63	8.61e-05	146	55	4	21399614
Pubmed	Crosstalk Between NDP52 and LUBAC in Innate Immune Responses, Cell Death, and Xenophagy.	CALCOCO2 IKBKB	8.78e-05	9	55	2	33815386
Pubmed	FBXO11 promotes ubiquitination of the Snail family of transcription factors in cancer progression and epidermal development.	TP63 FBXO11	8.78e-05	9	55	2	25827072
Pubmed	A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex.	UACA CHMP2A CHMP2B	1.03e-04	57	55	3	16730941
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CEP170 ROCK2 ANK3 UACA CLIP2 TAGLN3 ADGRB3 SLC12A5	1.29e-04	963	55	8	28671696
Pubmed	Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission.	CHMP2A CHMP2B	1.34e-04	11	55	2	36107470
Pubmed	Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease.	CHMP2A CHMP2B	1.34e-04	11	55	2	17984323
Pubmed	Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.	PTPN22 STAT4	1.34e-04	11	55	2	18204446
Pubmed	Ectoderm-targeted overexpression of the glucocorticoid receptor induces hypohidrotic ectodermal dysplasia.	TP63 IKBKB	1.34e-04	11	55	2	15746257
Pubmed	SKP2 attenuates NF-κB signaling by mediating IKKβ degradation through autophagy.	CALCOCO2 IKBKB	1.34e-04	11	55	2	29474632
Pubmed	Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch.	TP63 IKBKB	1.34e-04	11	55	2	17041603
Pubmed	Structure of cellular ESCRT-III spirals and their relationship to HIV budding.	CHMP2A CHMP2B	1.60e-04	12	55	2	24878737
Pubmed	Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication.	CEP170 CEP63	1.89e-04	13	55	2	26297806
Pubmed	ESCRT machinery is required for plasma membrane repair.	CHMP2A CHMP2B	1.89e-04	13	55	2	24482116
Pubmed	The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor.	CHMP2A CHMP2B	1.89e-04	13	55	2	16554368
Pubmed	Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.	SLC38A1 ROCK2 DCTN6 TACC1 RUFY1	1.99e-04	339	55	5	37232246
Pubmed	ESCRT-III controls nuclear envelope reformation.	CHMP2A CHMP2B	2.21e-04	14	55	2	26040713
Pubmed	Perp is a p63-regulated gene essential for epithelial integrity.	TP63 PKP1	2.21e-04	14	55	2	15797384
Pubmed	Cumulative association of 22 genetic variants with seropositive rheumatoid arthritis risk.	PTPN22 STAT4	2.54e-04	15	55	2	20233754
Pubmed	AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding.	CHMP2A CHMP2B	2.54e-04	15	55	2	14505569
Pubmed	Membrane scission by the ESCRT-III complex.	CHMP2A CHMP2B	2.54e-04	15	55	2	19234443
Pubmed	Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients.	PTPN22 STAT4	2.54e-04	15	55	2	20881011
Pubmed	Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.	CHMP2A CHMP2B	2.54e-04	15	55	2	26040712
Pubmed	Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1.	CHMP2A CHMP2B	2.54e-04	15	55	2	16505166
Pubmed	p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome.	TP63 PKP1	2.54e-04	15	55	2	23108156
Pubmed	Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance.	CHMP2A CHMP2B	2.54e-04	15	55	2	20616062
Pubmed	Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers.	PTPN22 STAT4	2.54e-04	15	55	2	20498205
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	CEP170 DDX31 RARS1 UACA CLIP2 SULT2A1 SRP54 FBXO11 CHMP2A	2.77e-04	1371	55	9	36244648
Pubmed	Genetic variants in the prediction of rheumatoid arthritis.	PTPN22 STAT4	2.90e-04	16	55	2	20439292
Pubmed	SLX4IP promotes RAP1 SUMOylation by PIAS1 to coordinate telomere maintenance through NF-κB and Notch signaling.	POT1 IKBKB	2.90e-04	16	55	2	34187905
Pubmed	Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus.	PTPN22 STAT4	2.90e-04	16	55	2	20848568
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	CHL1 ROCK2 RARS1 CCDC73	3.34e-04	208	55	4	33230847
Pubmed	Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain.	ANK3 SLC12A5	3.70e-04	18	55	2	31910261
Pubmed	The protein network of HIV budding.	CHMP2A CHMP2B	3.70e-04	18	55	2	14505570
Pubmed	Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins.	CHMP2A CHMP2B	3.70e-04	18	55	2	14519844
Pubmed	p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate.	TP63 PKP1	6.63e-04	24	55	2	28604778
Pubmed	Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS.	TP63 CHMP2B	6.63e-04	24	55	2	26115514
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	SLC38A1 SRP54 TACC1 RUFY1 CHMP2B	7.18e-04	449	55	5	31732153
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	CLIP2 TACC1 RUFY1	7.36e-04	111	55	3	22558309
Pubmed	Proteomic characterization of the human centrosome by protein correlation profiling.	CEP170 CEP63	7.79e-04	26	55	2	14654843
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ANK3 CLIP2 DCTN6 ADGRB3 FBXO11 MED13L TUBGCP5 CEP63	8.84e-04	1285	55	8	35914814
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	CEP170 UACA CEP63	9.22e-04	120	55	3	31413325
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	CALCOCO2 CEP170 ROCK2 CMPK1 RARS1 TAGLN3 SRP54 IKBKB	9.39e-04	1297	55	8	33545068
Pubmed	Membrane budding and scission by the ESCRT machinery: it's all in the neck.	CHMP2A CHMP2B	9.70e-04	29	55	2	20588296
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	CMPK1 DDAH1 RARS1 UACA NEB CHMP2A CHMP2B	1.06e-03	1016	55	7	19056867
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	UBE2R2 ZFAT BABAM1 DCTN6 FBXO11 MED13L TUBGCP5 RUFY1	1.09e-03	1327	55	8	32694731
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CEP170 ROCK2 UACA CLIP2 TUBGCP5	1.09e-03	493	55	5	15368895
Pubmed	ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling.	CHMP2A CHMP2B	1.11e-03	31	55	2	37573008
Pubmed	Genome-wide searching of rare genetic variants in WTCCC data.	ZFAT PTPN22	1.18e-03	32	55	2	20549515
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SLC38A1 SPATA7 CMPK1 ANK3 TACC1 RUFY1	1.39e-03	777	55	6	35844135
Pubmed	Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.	PTPN22 STAT4	1.58e-03	37	55	2	20453842
Cytoband	9q21.32	SPATA31D4 SPATA31D3	2.38e-04	19	55	2	9q21.32
GeneFamily	Charged multivesicular body proteins\|ESCRT-III	CHMP2A CHMP2B	5.94e-05	7	31	2	1118
GeneFamily	Charged multivesicular body proteins\|ESCRT-III associated factors	CHMP2A CHMP2B	1.55e-04	11	31	2	482
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#1_top-relative-expression-ranked_200	CHL1 TP63 PKP1	3.20e-05	24	55	3	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_200_k1
ToppCell	Neuron\|World / Primary Cells by Cluster	CHL1 SLC38A1 CEP170 ANK3 TAGLN3 RBFOX2	1.68e-07	199	55	6	1f8104fd92f04690b41d9d07ac08dc59d76bb97d
ToppCell	Neuron-Postmitotic\|World / Primary Cells by Cluster	CHL1 SLC38A1 CEP170 ANK3 TAGLN3 RBFOX2	1.68e-07	199	55	6	1973527f8a7d4c6490d75c0d0ea153688166a08b
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_\|World / Primary Cells by Cluster	CHL1 SLC38A1 CEP170 ANK3 TAGLN3 RBFOX2	1.68e-07	199	55	6	058373b4ac3cec2108cb24265628ff0a50646e33
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	CHL1 SLC38A1 CEP170 ANK3 TAGLN3 RBFOX2	1.73e-07	200	55	6	84e4565d28a02700bf7f6730d1b3a58744ca0aea
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	CHL1 SLC38A1 CEP170 ANK3 TAGLN3 RBFOX2	1.73e-07	200	55	6	1decf1d2cba5ebfd3e5cd4bcd637db8f193033ce
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Cortical_neuron\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	CHL1 SLC38A1 CEP170 ANK3 TAGLN3 RBFOX2	1.73e-07	200	55	6	19055194a5e0ea122f1b8fc62df44813f6843c95
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-Neurons\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	SLC38A1 CEP170 ANK3 TAGLN3 RBFOX2	4.68e-06	199	55	5	ae575ed7582f2a4218f6cbcbf5f7f0ce7a5bc26b
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CHL1 ANK3 UACA TP63 PKP1	4.79e-06	200	55	5	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Cortical_neuron\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	SLC38A1 CEP170 ANK3 TAGLN3 RBFOX2	4.79e-06	200	55	5	5b3df61ff421846ef4cabf1bd5355534c8b95509
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal\|10w / Sample Type, Dataset, Time_group, and Cell type.	CHL1 CEP170 ANK3 TAGLN3 RBFOX2	4.79e-06	200	55	5	979258173b82f37aeaaedd53b4a527da1dbe1b80
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	CHL1 SLC38A1 ROCK2 ANK3 RBFOX2	4.79e-06	200	55	5	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CHL1 ANK3 UACA TP63 PKP1	4.79e-06	200	55	5	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	LPS-antiTNF-Hematopoietic_Mast-Mast_cells-T-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TAGLN3 PAFAH2 PTPN22 STAT4	3.28e-05	147	55	4	1ecd7c084e73eb6fae1ab1f9aae17115d3d62cbd
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	SLC38A1 ANK3 PTPN22 STAT4	3.64e-05	151	55	4	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	Influenza_Severe-CD4+_CTL\|Influenza_Severe / Disease group and Cell class	GBP6 ANK3 SULT2A1 STAT4	5.02e-05	164	55	4	9ffd40ae1f39290840bea79fa4e73cb7e009f310
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP100 ZFAT TP63 PKP1	5.39e-05	167	55	4	29d271643f3a1718b53db77b7d093ec94225a824
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC38A1 PTPN22 NEB STAT4	5.39e-05	167	55	4	ded4d6cccd3660662f12cf5a512de31d26325f1b
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CHL1 PTPN22 NEB STAT4	5.39e-05	167	55	4	eed22d1a17aab84dacb1a488528bae9389644cb9
ToppCell	Control-Epithelial_cells-Airway_basal\|Control / group, cell type (main and fine annotations)	CHL1 TP63 PKP1 PLEKHS1	5.91e-05	171	55	4	3965ced4be6db14265a90673502fceee425837ca
ToppCell	normal-na-Lymphocytic_T-T4_em-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	SLC38A1 CMPK1 ANK3 SMCO2	5.91e-05	171	55	4	61318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZFAT PTPN22 IKBKB STAT4	5.91e-05	171	55	4	f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 PPARGC1B ANK3 PTPN22	6.32e-05	174	55	4	6987fe7959afce347282f632abc16d800ccab7c4
ToppCell	NS-critical-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP100 ANK3 ECSCR TAGLN3	6.60e-05	176	55	4	b794275fdd757b8fa2108e3c867f23da2649146d
ToppCell	nucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CHL1 TP63 PKP1 PLEKHS1	6.75e-05	177	55	4	cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCell	nucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CHL1 TP63 PKP1 PLEKHS1	6.75e-05	177	55	4	ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	UACA ECSCR TACC1 PARP14	6.90e-05	178	55	4	375156ba1c7b8592bf733c75f24968161f7cfa09
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 SLC38A1 DDAH1 TAGLN3	7.05e-05	179	55	4	7ae67e1c09a4ce9b3bcec4c48ee9cf2b1cb4e339
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CHL1 GBP6 TP63 PKP1	7.21e-05	180	55	4	535a890bde0d978b461c2d4c571529b585c76b21
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 ECSCR PKP1 PARP14	7.36e-05	181	55	4	0756d7d315b8cdd07a3cf6cdfc8a0679786b8e6a
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 ECSCR PKP1 PARP14	7.36e-05	181	55	4	b09947d2d7b21f96d98b87ceb6f467ea329c4092
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-24m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 ECSCR PKP1 PARP14	7.36e-05	181	55	4	3f0d88e9506d66d4e71b88c50d5187302065930f
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	SLC38A1 ANK3 IKBKB STAT4	7.36e-05	181	55	4	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	COVID-19-Epithelial_cells-Airway_basal\|COVID-19 / group, cell type (main and fine annotations)	ANK3 TP63 PKP1 PLEKHS1	8.35e-05	187	55	4	8407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell	droplet-Mammary_Gland-nan-3m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP6 UACA ECSCR PARP14	8.70e-05	189	55	4	1d4ad307c0606957dd7bf8da84450e5193cf4a50
ToppCell	droplet-Mammary_Gland-nan-3m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP6 UACA ECSCR PARP14	8.70e-05	189	55	4	b952026044d5f6c0adce60cf24f6e0199e6f8757
ToppCell	droplet-Mammary_Gland-nan-3m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP6 UACA ECSCR PARP14	8.70e-05	189	55	4	25781edbd08c6e413740b796ecc8ba1934bd3aa5
ToppCell	IPF-Lymphoid-T\|IPF / Disease state, Lineage and Cell class	SLC38A1 ANK3 PTPN22 STAT4	8.88e-05	190	55	4	d57df208aaf7a5554899bb9107c80b443fd0cf93
ToppCell	COVID-19-lung-CD4+_Treg\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC38A1 ANK3 PTPN22 STAT4	9.06e-05	191	55	4	5a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCell	COVID-19-T_cells-CD4+_T_cells\|COVID-19 / group, cell type (main and fine annotations)	SLC38A1 ANK3 PTPN22 STAT4	9.06e-05	191	55	4	0646cca78e24aeb6baa9934d3c439b797c567997
ToppCell	COVID-19-T_cells\|COVID-19 / group, cell type (main and fine annotations)	SLC38A1 ANK3 PTPN22 STAT4	9.06e-05	191	55	4	7f64add931b64b8d35836fa6bee9ebab593844d3
ToppCell	COVID-19-lung-CD4+_Treg\|lung / Disease (COVID-19 only), tissue and cell type	SLC38A1 ANK3 PTPN22 STAT4	9.06e-05	191	55	4	73ea3078c1f55cd47e4d99e77b3ce4ff17549d49
ToppCell	IPF-Lymphoid-NK\|World / Disease state, Lineage and Cell class	SLC38A1 PAFAH2 PTPN22 STAT4	9.06e-05	191	55	4	f206159b9d5e84cf14a65bfdc008895cec5a8081
ToppCell	COPD-Lymphoid-T\|World / Disease state, Lineage and Cell class	SLC38A1 ANK3 PTPN22 STAT4	9.25e-05	192	55	4	eb4909574fb5fc91399463523e2737095773200a
ToppCell	Control-Lymphoid-T\|World / Disease state, Lineage and Cell class	SLC38A1 ANK3 PTPN22 STAT4	9.25e-05	192	55	4	253cf4d2cf88ad8c45b73779336180840bef054b
ToppCell	IPF-Lymphoid-T\|World / Disease state, Lineage and Cell class	SLC38A1 ANK3 PTPN22 STAT4	9.25e-05	192	55	4	b25ba1f3bc842c22602b2aeed3b1b5082863e4fa
ToppCell	Control-Lymphoid-T\|Control / Disease state, Lineage and Cell class	SLC38A1 ANK3 PTPN22 STAT4	9.43e-05	193	55	4	af928046ccd1ca874be1534aef6ca7f27d90bc46
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CALCOCO2 SLC38A1 SPATA7 TAGLN3	9.43e-05	193	55	4	088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCell	COVID-19-lung-CD4+_T_cells_metabolically_active\|lung / Disease (COVID-19 only), tissue and cell type	SLC38A1 ANK3 PTPN22 STAT4	9.62e-05	194	55	4	2a144a1c2d537c8a59aa419206ddd96c23f0aeab
ToppCell	COPD-Lymphoid-T\|COPD / Disease state, Lineage and Cell class	SLC38A1 ANK3 PTPN22 STAT4	1.00e-04	196	55	4	30e53b8050d2a041f855d0e39bbd8f923c64c489
ToppCell	cellseq-Epithelial-Epithelial_Airway\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CHL1 TP63 PKP1 PLEKHS1	1.00e-04	196	55	4	faa39c567f24403e511b240c1d1a654ffadd8473
ToppCell	ILEUM-inflamed-(7)_Endothelial_cell-(7)_CD36+_endothelial_cells\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	UACA PPM1D TACC1 MED13L	1.02e-04	197	55	4	66339b5aae3952f5c484c9dcb0cfb4fbd828d4cb
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-midbrain/hindbrain_cells\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	CEP170 ANK3 TAGLN3 RBFOX2	1.02e-04	197	55	4	c7078f6fcf27319ba8c5ebe700bcae7f1e7e39c1
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CHL1 TP63 PKP1 PLEKHS1	1.02e-04	197	55	4	1e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	CEP170 ANK3 TAGLN3 RBFOX2	1.02e-04	197	55	4	2d92b0483d57541aee382dda80e42cf66e813d6b
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ROCK2 ADGRB3 RBFOX2 SLC12A5	1.04e-04	198	55	4	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Bronchial_Biopsy\|World / Tissue, Lineage and Cell class of Lung Cells from 10X	CHL1 UACA TP63 PKP1	1.04e-04	198	55	4	f5b7013045b61fc56894f80092f799770dde1c8f
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CHL1 TP63 PKP1 PLEKHS1	1.04e-04	198	55	4	19d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	SLC38A1 TAGLN3 RBFOX2	1.05e-04	74	55	3	a50df7f4f7847b8aeff3fc6d521a69b50e05c719
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CFAP100 ZFAT PKP1 PLEKHS1	1.06e-04	199	55	4	60919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW10-Neuronal\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	CEP170 ANK3 TAGLN3 RBFOX2	1.06e-04	199	55	4	b2508bf591720830e8e3494b1337aab14539956d
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 ADGRB3 MED13L RBFOX2	1.06e-04	199	55	4	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_anti-TNF-Epithelial_airway\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CFAP100 ZFAT PKP1 PLEKHS1	1.06e-04	199	55	4	6aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	CEP170 ANK3 TAGLN3 RBFOX2	1.06e-04	199	55	4	77b4aa00f14b86ef5db0490be98787e063979541
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CFAP100 ZFAT TP63 PKP1	1.08e-04	200	55	4	cf191104484bfb2b9f87de416b9453135f8833c1
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon\|organoid_Velasco_nature / Sample Type, Dataset, Time_group, and Cell type.	SLC38A1 ANK3 TAGLN3 RBFOX2	1.08e-04	200	55	4	f6d6a2f4e2f51c292dfb97280353a49117798fc6
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	ROCK2 GBP6 UACA PARP14	1.08e-04	200	55	4	edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCell	Nasal_Brush-Epithelial\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	CHL1 CMPK1 ANK3 PLEKHS1	1.08e-04	200	55	4	7911073119ee47a37b68b73fc54f063e902a5067
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Cortical_neuron\|5w / Sample Type, Dataset, Time_group, and Cell type.	CEP170 ANK3 TAGLN3 RBFOX2	1.08e-04	200	55	4	085060d148158f7d9e938b6c4a3700ccbb3bca15
ToppCell	Tracheal-10x5prime-Epithelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CHL1 ANK3 TP63 PLEKHS1	1.08e-04	200	55	4	efd461c687155c84ef590352207e6fe4ba392a90
ToppCell	LPS_IL1RA-Epithelial_airway\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CFAP100 ZFAT TP63 PKP1	1.08e-04	200	55	4	a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
ToppCell	Bronchial_Brush-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SLC38A1 TP63 PKP1 TACC1	1.08e-04	200	55	4	7595eb2a8af3de879ecaa71f3d96f890e13b59ce
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	CEP170 UBE2R2 ANK3 TAGLN3	1.08e-04	200	55	4	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_basal-Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CHL1 ANK3 TP63 PKP1	1.08e-04	200	55	4	9da214f756a03516eaafde00289b90f69623b9f3
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CHL1 TP63 PKP1 PLEKHS1	1.08e-04	200	55	4	8827653738a931e4a4545e0c7d75be12bed40740
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	CEP170 ANK3 TAGLN3 RBFOX2	1.08e-04	200	55	4	04699d1149a143b96d6f292c0d70c4d3e6dfc611
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_basal-Suprabasal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CHL1 TP63 PKP1 PLEKHS1	1.08e-04	200	55	4	ce969c958a31145bbfe315a9a865d7900ecc9549
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CHL1 ANK3 TP63 PKP1	1.08e-04	200	55	4	2a9d715aba8bdef2341b0d44ff60825c074a4b03
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal\|5w / Sample Type, Dataset, Time_group, and Cell type.	CEP170 ANK3 TAGLN3 RBFOX2	1.08e-04	200	55	4	9b5753726c17dda98d7384a60f26a5eaf4f6c4d6
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital\|World / Primary Cells by Cluster	CHL1 CEP170 ANK3 RBFOX2	1.08e-04	200	55	4	6bbe8e1f3e91678f1bfb14945365c1578a59a604
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital-19\|World / Primary Cells by Cluster	CHL1 CEP170 ANK3 RBFOX2	1.08e-04	200	55	4	c831d9e0a7178e3634da45548f91fa9e8dc6557c
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6-Slc17a7.Nr4a2_(Claustrum)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FSIP2 PKP1 STAT4	1.23e-04	78	55	3	564ea2c113058df595c3b69827cf9a72380b48fc
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6-Slc17a7.Nr4a2_(Claustrum)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FSIP2 PKP1 STAT4	1.23e-04	78	55	3	dfe16ac0b10dce7ecf4b3a0b4e1013ac58cb9fc1
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Slc17a6-Slc17a7.Nr4a2_(Claustrum)--\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FSIP2 PKP1 STAT4	1.23e-04	78	55	3	6aa418ea30dfa7df2fc08cac5b31e3a654aaa7f0
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW08-Neuronal\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	ANK3 TAGLN3 RBFOX2	1.33e-04	80	55	3	5c39136f5f855efbf61e1f5348ea97ea2130b241
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Neuronal\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	SLC38A1 TAGLN3 RBFOX2	1.43e-04	82	55	3	dadc97c81e44858f60687145316102fc10ecc13e
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	SLC38A1 TAGLN3 RBFOX2	3.59e-04	112	55	3	9c3fb470708e76a8f8a3cb9aa17ab130c60fee11
ToppCell	Endothelial-Endothelial-F\|Endothelial / shred on cell class and cell subclass (v4)	GBP6 UACA PARP14	4.60e-04	122	55	3	2cb8bb63c69aed4d4504b9d97219b8707666f950
ToppCell	LPS_only-Lymphocytic_NKT-T_cells-iNKT-MAIT\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PAFAH2 PTPN22 STAT4	4.83e-04	124	55	3	05e114fcfe84cfc8d92978a4eda6db4d8a616e0e
ToppCell	LPS-IL1RA-Hematopoietic_Mast-Mast_cells-T-cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PAFAH2 PTPN22 STAT4	6.59e-04	138	55	3	10c263c58b83a018791f77098f18927d904cb13b
ToppCell	Endothelial-F\|World / shred on cell class and cell subclass (v4)	GBP6 UACA ECSCR	6.73e-04	139	55	3	32d3c5d35e6c4205711c3500d736fd108443e6b4
ToppCell	LPS-IL1RA-Hematopoietic_Mast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PAFAH2 PTPN22 STAT4	7.16e-04	142	55	3	f7d0d5ca9fc3dd929d4fdd59b71bfa623007e992
ToppCell	LPS-IL1RA-Hematopoietic_Mast-Mast_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PAFAH2 PTPN22 STAT4	7.16e-04	142	55	3	2a9a070e7c53ac593d46c6c5f6983f07d4413501
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PAFAH2 PTPN22 STAT4	7.76e-04	146	55	3	a5c84ad44d6ffb25028a4fd5454fd5de81b16a5e
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Mast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PAFAH2 PTPN22 STAT4	7.76e-04	146	55	3	8133037881c15e75637fc616091a7055488dd5fc
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	PPARGC1B SLC12A5 CEP63	7.92e-04	147	55	3	b2196046656157d7fcf5b5d1cec7bf521b1e5d8e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Cortical_neuron\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	SLC38A1 TAGLN3 RBFOX2	8.07e-04	148	55	3	a1269312903fc27830c1835dabf660c659a711be
ToppCell	LPS-antiTNF-Hematopoietic_Mast-Mast_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PAFAH2 PTPN22 STAT4	8.23e-04	149	55	3	59aa1f2a5cbeba64c4529fb05f544db17fd8b188
ToppCell	LPS-antiTNF-Hematopoietic_Mast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PAFAH2 PTPN22 STAT4	8.23e-04	149	55	3	1527cdd98a2734cbf8ce4c6170557280b71c55cb
ToppCell	LPS_only-Hematopoietic_Mast-Mast_cells-T-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PAFAH2 PTPN22 STAT4	8.39e-04	150	55	3	ccb782fbcb3122266354a112a9a850506664f44d
ToppCell	LPS_only-Hematopoietic_Mast-Mast_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PAFAH2 PTPN22 STAT4	8.39e-04	150	55	3	7290e9a812b1b2f919e67ccde0acf52687ab138f
Disease	rheumatoid arthritis, ACPA-negative rheumatoid arthritis	PTPN22 STAT4	2.92e-05	5	51	2	EFO_0000685, EFO_0009460
Disease	Juvenile pauciarticular chronic arthritis	PTPN22 STAT4	6.12e-05	7	51	2	C2931171
Disease	ectodermal dysplasia (is_implicated_in)	TP63 PKP1	6.12e-05	7	51	2	DOID:2121 (is_implicated_in)
Disease	asymmetrical dimethylarginine measurement	ZFAT DDAH1	8.15e-05	8	51	2	EFO_0006522
Disease	Systemic lupus erythematosus	PTPN22 STAT4	1.59e-04	11	51	2	cv:C0024141
Disease	psoriatic arthritis (is_implicated_in)	PTPN22 STAT4	1.59e-04	11	51	2	DOID:9008 (is_implicated_in)
Disease	lung carcinoma	CEP170 ZFAT TP63 POT1 RUFY1 SMCO2	1.78e-04	482	51	6	EFO_0001071
Disease	autoimmune thyroiditis (is_implicated_in)	ZFAT PTPN22	1.91e-04	12	51	2	DOID:7188 (is_implicated_in)
Disease	Fetal Alcohol Spectrum Disorders	CHL1 ANK3	2.26e-04	13	51	2	C2985290
Disease	Fetal Alcohol Syndrome	CHL1 ANK3	3.92e-04	17	51	2	C0015923
Disease	Sjogren's syndrome (is_implicated_in)	PTPN22 STAT4	4.40e-04	18	51	2	DOID:12894 (is_implicated_in)
Disease	nevus count, cutaneous melanoma	PPARGC1B POT1 MED13L	5.31e-04	91	51	3	EFO_0000389, EFO_0004632
Disease	Vitiligo	PPARGC1B PTPN22 STAT4	7.19e-04	101	51	3	EFO_0004208
Disease	systemic scleroderma (is_implicated_in)	PTPN22 STAT4	7.89e-04	24	51	2	DOID:418 (is_implicated_in)
Disease	TEMPS-A questionnaire	ZFAT ADGRB3	8.57e-04	25	51	2	EFO_0004783
Disease	estradiol measurement	PPARGC1B SULT2A1 FBXO11	9.22e-04	110	51	3	EFO_0004697
Disease	Hashimoto's thyroiditis	PTPN22 STAT4	9.27e-04	26	51	2	EFO_0003779
Disease	immune system disease	PTPN22 STAT4	1.08e-03	28	51	2	EFO_0000540
Disease	response to corticosteroid	ZFAT ANK3	1.15e-03	29	51	2	GO_0031960
Disease	psoriasis (is_implicated_in)	PTPN22 STAT4	1.59e-03	34	51	2	DOID:8893 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
MTSQKSFQQLTMEKE	TACC1	661	O75410
PSQEMDKMLKNQATS	CEP170	471	Q5SW79
VNNQPSMKEESKMNI	ADGRB3	1316	O60242
KDKVQQATSENMGLM	CLIP2	596	Q9UDT6
QTLKSNNSMAQAMKG	CHMP2A	91	O43633
KVTSMSTQTKVMNSQ	CHMP2B	81	Q9UQN3
EVNNATARVMTNKKM	RBFOX2	191	O43251
STTKAAKMMNQQRTK	PTPN22	331	Q9Y2R2
GQMMKNSVDSVKNST	KIAA1107	256	Q9UPP5
RMTSLKSNAKNMVTN	NMBR	361	P28336
DKQMAVPSRNTSKQM	MED13L	526	Q71F56
QKMPMKLTVNSSNSI	CHL1	216	O00533
NNSCLSKMKNSMASM	IKBKB	461	O14920
SKMKNSMASMSQQLK	IKBKB	466	O14920
QSREMTNKNQKMAAA	FSIP2	1461	Q5CZC0
NQVELATNMKMFTSK	FSIP2	3156	Q5CZC0
FQQKLMSKKNMNSTL	CSTL1	31	Q9H114
MSKKNMNSTLNFFIQ	CSTL1	36	Q9H114
NQEFQKKFMETTMNK	GBP6	376	Q6ZN66
TEQQATKENLMKMQS	TUBGCP5	616	Q96RT8
TNSTNTVMDQKNLKM	PPM1D	501	O15297
NTVLKMSSMTSVQKQ	DDX31	246	Q9H8H2
TMDAKNGQTMNEKQL	PARP14	1666	Q460N5
LNKMNSMNKLPSVSQ	TP63	466	Q9H3D4
SKTNALNVSQKMIEM	BABAM1	116	Q9NWV8
NVTMKDNKIMNNQDA	FBXO11	811	Q86XK2
MNTKSQLEISTQMCK	CEP63	521	Q96MT8
QNSDMKQQQQMEKGT	C9orf43	351	Q8TAL5
KTMCKNMSDMQNSQF	CCDC73	746	Q6ZRK6
SMKNINMNNGKQSLS	ECSCR	186	Q19T08
QNETTAMKKQQELMD	CALCOCO2	291	Q13137
MSNTKASKMKQVSQS	ANK3	3881	Q12955
KNMTNDKNSLESMNI	CFAP100	11	Q494V2
ENMSIQLDSTFKQMK	MS4A14	261	Q96JA4
MDQTMAANAQKNKFL	CMPK1	76	P30085
SQAMKMGDNNVIESK	DCTN6	96	O00399
SESAQKALKIMQQMS	DDAH1	191	O94760
NTEKFQTMESVNLMK	PAFAH2	281	Q99487
QMDDNSIQMKKDLTT	SLC12A5	886	Q9H2X9
MMTVKRQKSKSSQSS	PKP1	46	Q13835
NSAMGISQMLKTKEQ	RARS1	116	P54136
MSKNVSQSQMAKLNQ	SRP54	446	P61011
SQSQMAKLNQQMAKM	SRP54	451	P61011
SESKMAFKQMEQISQ	TAGLN3	81	Q9UI15
SFEGKTNQVMSSMKQ	RUFY1	486	Q96T51
TKLQSMNSENQTMLS	POT1	246	Q9NUX5
DSTQDKKAPMMQSQS	PPARGC1B	196	Q86YN6
SQEMSFLSSNKQKML	SPATA31D4	886	Q6ZUB0
KNSSFQSMKENKMSN	SULT2A1	216	Q06520
QSMKENKMSNYSLLS	SULT2A1	221	Q06520
GISSQEKMQSVQKMF	PLEKHS1	76	Q5SXH7
SQEMSFLSSNKQKML	SPATA31D3	886	P0C874
MKVLNSLQKKQMNTS	ZFAT	716	Q9P243
KTIQTMDQSDKNSAM	STAT4	176	Q14765
KMQTQQVNTLKMSEK	ROCK2	811	O75116
ETKNMTDSEMNIKQA	SPATA7	291	Q9P0W8
TNLNNKMSLQMKMDC	SMCO2	6	A6NFE2
SENTNLKKMMSNQYV	UACA	846	Q9BZF9
KMSSLSQSMRKVQDS	UACA	931	Q9BZF9
MAQQQMTSSQKALML	UBE2R2	1	Q712K3
DRSQKKMQMVSNISF	SLC38A1	301	Q9H2H9
TMEQALNKSNKLNMD	NEB	1731	P20929