Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentZ disc

FLNB SLC8A1 ANK2 SCN8A SYNPO

2.11e-04151755GO:0030018
GeneOntologyCellularComponentSchaffer collateral - CA1 synapse

NEFL APBA1 SYNPO CDH11 NOTCH1

2.39e-04155755GO:0098685
GeneOntologyCellularComponentsarcomere

FLNB SLC8A1 ANK2 SCN8A STYXL2 SYNPO

2.73e-04249756GO:0030017
GeneOntologyCellularComponentI band

FLNB SLC8A1 ANK2 SCN8A SYNPO

3.28e-04166755GO:0031674
GeneOntologyCellularComponentmyofibril

FLNB SLC8A1 ANK2 SCN8A STYXL2 SYNPO

4.45e-04273756GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

FLNB SLC8A1 ANK2 SCN8A STYXL2 SYNPO

6.11e-04290756GO:0043292
GeneOntologyCellularComponentchromatin

ERCC6 BAZ2A CTR9 RHOXF2 ARX TONSL ZFHX2 XPC IRX3 ANAPC7 KAT14 AKAP8L RCOR2 ZFX

7.04e-0414807514GO:0000785
GeneOntologyCellularComponentsupramolecular fiber

TUBA1B NEFL FLNB SLC8A1 ANK2 TUBA1A SCN8A AKNA STYXL2 SYNPO DYSF KIF3A

9.47e-0411797512GO:0099512
GeneOntologyCellularComponentpostsynapse

PRR12 NEFL SLC8A1 ANK2 SCN8A APBA1 PARN SYNPO ATP2B1 NOTCH1 KIF3A

9.72e-0410187511GO:0098794
GeneOntologyCellularComponentsupramolecular polymer

TUBA1B NEFL FLNB SLC8A1 ANK2 TUBA1A SCN8A AKNA STYXL2 SYNPO DYSF KIF3A

1.00e-0311877512GO:0099081
GeneOntologyCellularComponenttranscription elongation factor complex

ERCC6 CTR9 TONSL

1.07e-0356753GO:0008023
GeneOntologyCellularComponentsite of DNA damage

ERCC6 TONSL HTATSF1 XPC

1.50e-03137754GO:0090734
DomainDUF4211

PRR12 QSER1

4.63e-053742PF13926
DomainDUF4211

PRR12 QSER1

4.63e-053742IPR025451
DomainNaCa_Exmemb

SLC8A1 SLC24A1

5.48e-049742IPR004837
DomainNa_Ca_ex

SLC8A1 SLC24A1

5.48e-049742PF01699
DomainAlpha_tubulin

TUBA1B TUBA1A

5.48e-049742IPR002452
DomainTPR_8

CTR9 TONSL ANAPC7

1.21e-0353743PF13181
DomainAT_hook

PRR12 BAZ2A

1.79e-0316742PF02178
Domain-

TUBA1B TUBA1A

2.81e-03207423.30.1330.20
Domain-

TUBA1B TUBA1A

3.10e-03217421.10.287.600
DomainTubulin_C

TUBA1B TUBA1A

3.40e-0322742SM00865
DomainTubulin_C

TUBA1B TUBA1A

3.40e-0322742PF03953
DomainTubulin/FtsZ_2-layer-sand-dom

TUBA1B TUBA1A

3.40e-0322742IPR018316
Domain-

TUBA1B TUBA1A

3.40e-03227423.40.50.1440
DomainTubulin_C

TUBA1B TUBA1A

3.71e-0323742IPR023123
DomainTUBULIN

TUBA1B TUBA1A

3.71e-0323742PS00227
DomainTubulin

TUBA1B TUBA1A

3.71e-0323742IPR000217
DomainTub_FtsZ_C

TUBA1B TUBA1A

3.71e-0323742IPR008280
DomainTubulin

TUBA1B TUBA1A

3.71e-0323742SM00864
DomainTubulin_CS

TUBA1B TUBA1A

3.71e-0323742IPR017975
DomainTubulin_FtsZ_GTPase

TUBA1B TUBA1A

4.04e-0324742IPR003008
DomainTubulin

TUBA1B TUBA1A

4.04e-0324742PF00091
DomainCadherin_cytoplasmic-dom

CDH11 CDH18

4.38e-0325742IPR000233
DomainCadherin_C

CDH11 CDH18

4.38e-0325742PF01049
DomainAT_hook

PRR12 BAZ2A

5.10e-0327742SM00384
DomainAT_hook_DNA-bd_motif

PRR12 BAZ2A

5.10e-0327742IPR017956
Domain-

RHOXF2 ARX ZFHX2 IRX3 RCOR2

5.30e-032837451.10.10.60
DomainZnF_U1

WBP4 ZFHX2

5.87e-0329742SM00451
DomainZnf_U1

WBP4 ZFHX2

5.87e-0329742IPR003604
DomainCatenin_binding_dom

CDH11 CDH18

5.87e-0329742IPR027397
Domain-

CDH11 CDH18

5.87e-03297424.10.900.10
DomainHomeobox_CS

RHOXF2 ARX ZFHX2 IRX3

6.37e-03186744IPR017970
DomainHMGI/Y_DNA-bd_CS

PRR12 BAZ2A

6.69e-0331742IPR000637
PathwayREACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS

TUBA1B NEFL TUBA1A APBA1

2.51e-0544554M27934
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

PRR12 INTS14 TUBA1A BAZ2A CTR9 TONSL HTATSF1 AATF XPC PAGR1 QSER1 HNRNPUL1 MED17 ANAPC7 KAT14 ZFX

1.63e-081294761630804502
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

NEFL FLNB ARX WRNIP1 AATF SYNPO HNRNPUL1 NOTCH1 LRRC73 RUSC2

3.98e-07560761021653829
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

PRR12 INTS14 TONSL WRNIP1 PARN HNRNPUL1 MED17 ATP2B1 AKAP8L

6.56e-0745376929656893
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

BAZ2A CTR9 WRNIP1 KRI1 HTATSF1 AATF CDK11B

1.34e-0625176728077445
Pubmed

Dysferlin interacts with tubulin and microtubules in mouse skeletal muscle.

TUBA1B TUBA1A DYSF

1.63e-061176320405035
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

PRR12 TNRC18 CTR9 WRNIP1 PAGR1 QSER1 MED17

2.07e-0626876733640491
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TUBA1B NEFL FLNB RAP1GAP ANK2 CTR9 APBA1 ZBTB47 SYNPO XPC HNRNPUL1 AKAP8L KIF3A

3.95e-061285761335914814
Pubmed

PMCA activity and membrane tubulin affect deformability of erythrocytes from normal and hypertensive human subjects.

TUBA1A ATP2B1

4.71e-06276226307527
Pubmed

Impact of global genome repair versus transcription-coupled repair on ultraviolet carcinogenesis in hairless mice.

ERCC6 XPC

4.71e-06276210850428
Pubmed

Genetic variation in the nucleotide excision repair pathway and colorectal cancer risk.

ERCC6 XPC

4.71e-06276217119055
Pubmed

The conserved Cockayne syndrome B-piggyBac fusion protein (CSB-PGBD3) affects DNA repair and induces both interferon-like and innate antiviral responses in CSB-null cells.

ERCC6 PGBD3

4.71e-06276222483866
Pubmed

Nonsyndromic Early-Onset Cone-Rod Dystrophy and Limb-Girdle Muscular Dystrophy in a Consanguineous Israeli Family are Caused by Two Independent yet Linked Mutations in ALMS1 and DYSF.

ALMS1 DYSF

4.71e-06276226077327
Pubmed

Expanding the phenotype in Adams-Oliver syndrome correlating with the genotype.

DOCK6 NOTCH1

4.71e-06276231654484
Pubmed

Ankyrin-B directs membrane tethering of periaxin and is required for maintenance of lens fiber cell hexagonal shape and mechanics.

ANK2 PRX

4.71e-06276226538089
Pubmed

Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I-DNA covalent complex.

ERCC6 PGBD3

4.71e-06276221143350
Pubmed

Targeting and stability of Na/Ca exchanger 1 in cardiomyocytes requires direct interaction with the membrane adaptor ankyrin-B.

SLC8A1 ANK2

4.71e-06276217178715
Pubmed

Targeting Cadherin-11 Prevents Notch1-Mediated Calcific Aortic Valve Disease.

CDH11 NOTCH1

4.71e-06276228606953
Pubmed

Analysis of tubulin alpha-1A/1B C-terminal tail post-translational poly-glutamylation reveals novel modification sites.

TUBA1B TUBA1A

4.71e-06276222296162
Pubmed

What role (if any) does the highly conserved CSB-PGBD3 fusion protein play in Cockayne syndrome?

ERCC6 PGBD3

4.71e-06276223369858
Pubmed

Modulation of the stability and activities of HIV-1 Tat by its ubiquitination and carboxyl-terminal region.

TUBA1B TUBA1A

4.71e-06276225328666
Pubmed

Dysmyelination not demyelination causes neurological symptoms in preweaned mice in a murine model of Cockayne syndrome.

ERCC6 XPC

4.71e-06276222393014
Pubmed

Nucleotide excision repair-initiating proteins bind to oxidative DNA lesions in vivo.

ERCC6 XPC

4.71e-06276223253478
Pubmed

An abundant evolutionarily conserved CSB-PiggyBac fusion protein expressed in Cockayne syndrome.

ERCC6 PGBD3

4.71e-06276218369450
Pubmed

Plasma membrane Ca2+-ATPase and NCX1 Na+/Ca2+ exchanger expression in distal convoluted tubule cells.

SLC8A1 ATP2B1

4.71e-06276212060584
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

FLNB ANK2 BAZ2A SLC24A1 RGL2 CDH11 PRX

7.95e-0632976717474147
Pubmed

Interaction network of human early embryonic transcription factors.

PRR12 TNRC18 ALMS1 PAGR1 QSER1 KAT14 AKAP8L

1.21e-0535176738297188
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PRR12 RAP1GAP CTR9 TONSL PARN QSER1 QSOX2 AKAP8L RUSC2

1.23e-0565076938777146
Pubmed

Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation.

TUBA1B TUBA1A

1.41e-05376231767681
Pubmed

Tethering of the conserved piggyBac transposase fusion protein CSB-PGBD3 to chromosomal AP-1 proteins regulates expression of nearby genes in humans.

ERCC6 PGBD3

1.41e-05376223028371
Pubmed

Mutations in Cockayne Syndrome-Associated Genes (Csa and Csb) Predispose to Cisplatin-Induced Hearing Loss in Mice.

ERCC6 XPC

1.41e-05376227122034
Pubmed

A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritis.

ACAN NOTCH1

1.41e-05376226198357
Pubmed

Relationship between UV-induced mutant p53 patches and skin tumours, analysed by mutation spectra and by induction kinetics in various DNA-repair-deficient mice.

ERCC6 XPC

1.41e-05376216051635
Pubmed

ADP-ribosylation factor like 7 (ARL7) interacts with alpha-tubulin and modulates intracellular vesicular transport.

TUBA1B TUBA1A

1.41e-05376219409876
Pubmed

Laryngeal neuropathy of Charcot-Marie-Tooth disease: further observations and novel mutations associated with vocal fold paresis.

NEFL PRX

1.41e-05376219950375
Pubmed

Differential role of transcription-coupled repair in UVB-induced G2 arrest and apoptosis in mouse epidermis.

ERCC6 XPC

1.41e-05376211005836
Pubmed

Association of transcription-coupled repair but not global genome repair with ultraviolet-B-induced Langerhans cell depletion and local immunosuppression.

ERCC6 XPC

1.41e-05376214632192
Pubmed

Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions.

TUBA1B TUBA1A

1.41e-0537626646120
Pubmed

Synaptotagmin 2 couples mucin granule exocytosis to Ca2+ signaling from endoplasmic reticulum.

ANK2 SYT2

1.41e-05376219208631
Pubmed

Selective DNA damage responses in murine Xpa-/-, Xpc-/- and Csb-/- keratinocyte cultures.

ERCC6 XPC

1.41e-05376216182614
Pubmed

Differential ultraviolet-B-induced immunomodulation in XPA, XPC, and CSB DNA repair-deficient mice.

ERCC6 XPC

1.41e-05376211442761
Pubmed

2-AAF-induced tumor development in nucleotide excision repair-deficient mice is associated with a defect in global genome repair but not with transcription coupled repair.

ERCC6 XPC

1.41e-05376215533832
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

PRR12 TUBA1B ERCC6 TUBA1A ACAN SYNPO HNRNPUL1 AKAP8L

1.66e-0551376825798074
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

BAZ2A TONSL HTATSF1 XPC RCOR2

2.02e-0515076528242625
Pubmed

WW domains provide a platform for the assembly of multiprotein networks.

WBP4 WRNIP1 HTATSF1 CDK11B HNRNPUL1

2.29e-0515476516055720
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

INTS14 TONSL AATF PARN XPC HNRNPUL1 ANAPC7

2.54e-0539476727248496
Pubmed

X11alpha impairs gamma- but not beta-cleavage of amyloid precursor protein.

APBA1 NOTCH1

2.82e-05476214756819
Pubmed

Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.

ERCC6 XPC

2.82e-05476217326724
Pubmed

Mouse model for the DNA repair/basal transcription disorder trichothiodystrophy reveals cancer predisposition.

ERCC6 XPC

2.82e-05476210416615
Pubmed

Transcription-coupled and global genome repair differentially influence UV-B-induced acute skin effects and systemic immunosuppression.

ERCC6 XPC

2.82e-05476210843671
Pubmed

DMBA-induced toxic and mutagenic responses vary dramatically between NER-deficient Xpa, Xpc and Csb mice.

ERCC6 XPC

2.82e-05476211408355
Pubmed

Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation.

TUBA1A KIF3A

2.82e-05476227793670
Pubmed

Plasma membrane-cytoskeleton-endoplasmic reticulum complexes in neurons and astrocytes.

SLC8A1 ANK2

2.82e-05476214593108
Pubmed

Recognition of C-terminal amino acids in tubulin by pore loops in Spastin is important for microtubule severing.

TUBA1B TUBA1A

2.82e-05476217389232
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

INTS14 ERCC6 ALMS1 BAZ2A WRNIP1 XPC ANAPC7 KAT14 QSOX2 AKAP8L RCOR2

3.00e-051116761131753913
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

TNRC18 INTS14 TUBA1A CTR9 QSER1 ANAPC7

3.66e-0528276623667531
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

TUBA1B BAZ2A WBP4 KRI1 HTATSF1 AATF PARN CDK11B QSER1 HNRNPUL1

4.27e-05954761036373674
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

TNRC18 TONSL HTATSF1 APOBR RNF115 NOTCH1 PRX

4.41e-0543076735044719
Pubmed

XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathways.

ERCC6 XPC

4.69e-05576232271760
Pubmed

Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology.

ERCC6 XPC

4.69e-05576222174697
Pubmed

The effect of DNA repair defects on reproductive performance in nucleotide excision repair (NER) mouse models: an epidemiological approach.

ERCC6 XPC

4.69e-05576216315091
Pubmed

Five mouse tubulin isotypes and their regulated expression during development.

TUBA1B TUBA1A

4.69e-0557623839797
Pubmed

A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly.

ANK2 KIF3A

4.69e-05576222632975
Pubmed

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo.

TUBA1B TUBA1A

4.69e-05576212606581
Pubmed

Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain.

SLC8A1 ANK2

4.69e-05576216292983
Pubmed

Polymorphisms in nucleotide excision repair genes and risk of multiple primary melanoma: the Genes Environment and Melanoma Study.

ERCC6 XPC

4.69e-05576216258177
Pubmed

The involvement of key DNA repair pathways in the formation of chromosome rearrangements in embryonic stem cells.

ERCC6 XPC

4.69e-05576215979950
Pubmed

Tissue specific mutagenic and carcinogenic responses in NER defective mouse models.

ERCC6 XPC

4.69e-05576216769089
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

BAZ2A CTR9 WRNIP1 XPC PAGR1 CDK11B HNRNPUL1 AKAP8L ZFX

4.81e-0577476915302935
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

CTR9 WRNIP1 AATF CDK11B HNRNPUL1 MED17 AKAP8L

5.10e-0544076734244565
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

TUBA1B TUBA1A CTR9 KRI1 HTATSF1 AATF CDK11B AKAP8L

5.34e-0560576828977666
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

TUBA1B ERCC6 BAZ2A SYNPO XPC CDK11B QSER1 ANAPC7

5.53e-0560876836089195
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

TUBA1B FLNB CTR9 WRNIP1 KRI1 AATF PARN CDK11B HNRNPUL1 AKAP8L

5.77e-05989761036424410
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

TUBA1B NEFL MXRA5 ALMS1 TUBA1A

5.78e-0518776526460568
Pubmed

Analysis of genes from inner ear developmental-stage cDNA subtraction reveals molecular regionalization of the otic capsule.

FLNB ACAN CDH11

6.24e-053576315031101
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

NEFL FLNB TNRC18 ANK2 CTR9 AATF SYNPO XPC ATP2B1 ANAPC7 AKAP8L PRX

6.56e-051442761235575683
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

TUBA1B INTS14 TUBA1A BAZ2A KRI1 HTATSF1 HNRNPUL1 ANAPC7 KIF3A

6.76e-0580976932129710
Pubmed

The N-terminal domain of c-Myc associates with alpha-tubulin and microtubules in vivo and in vitro.

TUBA1B TUBA1A

7.03e-0567627651436
Pubmed

Six mouse alpha-tubulin mRNAs encode five distinct isotypes: testis-specific expression of two sister genes.

TUBA1B TUBA1A

7.03e-0567623785200
Pubmed

Ankyrin-B regulates Kir6.2 membrane expression and function in heart.

SLC8A1 ANK2

7.03e-05676220610380
Pubmed

USP7-mediated deubiquitination differentially regulates CSB but not UVSSA upon UV radiation-induced DNA damage.

ERCC6 XPC

7.03e-05676231775559
Pubmed

Na+ dysregulation coupled with Ca2+ entry through NCX1 promotes muscular dystrophy in mice.

SLC8A1 DYSF

7.03e-05676224662047
Pubmed

Abnormal arterial-venous fusions and fate specification in mouse embryos lacking blood flow.

SLC8A1 NOTCH1

7.03e-05676228931948
Pubmed

Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response.

ERCC6 XPC

7.03e-05676234819667
Pubmed

The chromatin modifying complex CoREST/LSD1 negatively regulates notch pathway during cerebral cortex development.

NOTCH1 RCOR2

7.03e-05676227112428
Pubmed

Polymorphisms in nucleotide excision repair genes, smoking and breast cancer in African Americans and whites: a population-based case-control study.

ERCC6 XPC

7.03e-05676216399771
Pubmed

Analysis of estrogen receptor alpha signaling complex at the plasma membrane.

TUBA1B TUBA1A

7.03e-05676215556606
Pubmed

Sodium/calcium exchanger expression in the mouse and rat olfactory systems.

SLC8A1 SLC24A1

7.03e-05676217311327
Pubmed

Mutation analysis of 12 candidate genes for distal hereditary motor neuropathy type II (distal HMN II) linked to 12q24.3.

TUBA1B TUBA1A

7.03e-05676212090300
Pubmed

Adams-Oliver Syndrome – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

DOCK6 NOTCH1

7.03e-05676227077170
Pubmed

Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange.

SLC8A1 ATP2B1

7.03e-05676212767889
Pubmed

Three-dimensional molecular architecture of mouse organogenesis.

NEFL ACAN ARX IRX3

7.04e-0510076437524711
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

EHBP1L1 MXRA5 WBP4 AATF FGD5 XPC MED17 ATP2B1

7.73e-0563876831182584
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ALMS1 TECPR2 BAZ2A RUSC2

8.20e-051047649205841
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

TUBA1B RAP1GAP CTR9 WRNIP1 AATF PAGR1 DOCK6 ANAPC7 AKAP8L RUSC2

8.61e-051038761026673895
Pubmed

Codon modification of Tuba1a alters mRNA levels and causes a severe neurodevelopmental phenotype in mice.

TUBA1B TUBA1A

9.83e-05776236681692
Pubmed

Retinoic acid-dependent signaling pathways and lineage events in the developing mouse spinal cord.

IRX3 NOTCH1

9.83e-05776222396766
Pubmed

Modulation of nucleotide excision repair in human lymphocytes by genetic and dietary factors.

ERCC6 XPC

9.83e-05776219878615
Pubmed

Nucleotide excision repair gene polymorphisms and risk of advanced colorectal adenoma: XPC polymorphisms modify smoking-related risk.

ERCC6 XPC

9.83e-05776216492920
Pubmed

Nucleotide excision repair pathway genes and oral premalignant lesions.

ERCC6 XPC

9.83e-05776217575242
Pubmed

Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.

ANK2 SCN8A

9.83e-05776215272007
InteractionSIRT6 interactions

FLNB TUBA1A CTR9 TONSL WRNIP1 AATF XPC CDK11B HNRNPUL1 MED17 ANAPC7 AKAP8L

3.28e-066287512int:SIRT6
CytobandXp21.3

ARX ZFX

1.07e-0329762Xp21.3
Cytoband12q13.12

TUBA1B TUBA1A

1.83e-033876212q13.12
GeneFamilyCD molecules|Type II classical cadherins

CDH11 CDH18

4.44e-04134421186
GeneFamilyTubulins

TUBA1B TUBA1A

1.81e-0326442778
GeneFamilyAnkyrin repeat domain containing

ANK2 TONSL ACBD6 NOTCH1

2.79e-03242444403
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HOMTN

NEFL ANK2 TUBA1A SCN8A IRX3 SYT2 ATP2B1 RCOR2 KIF3A

1.69e-06389759M39073
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB ZFHX2 SYNPO DOCK6 CDH11 NOTCH1

4.36e-0716876606dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB ZFHX2 SYNPO DOCK6 CDH11 NOTCH1

4.36e-071687661002f058a340763e3d8de0bd1f0547a903526ec6
ToppCellfacs-Kidney-nan-24m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNPO FGD5 IRX3 DYSF DOCK6 NOTCH1

8.69e-071897669d02a824bba59ea0660439f0510d843568e9d8c3
ToppCellfacs-Kidney-nan-24m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNPO FGD5 IRX3 DYSF DOCK6 NOTCH1

8.69e-071897665f8d4b61296c71b32362432a9ce4c1c3aaeb278d
ToppCellfacs-Kidney-nan-24m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNPO FGD5 IRX3 DYSF DOCK6 NOTCH1

8.69e-0718976618f82764b32496e54d1a604a531b261651c5e110
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Neuronal-CPNs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

NEFL SLC8A1 ANK2 ATP2B1 CDH11 LRRC73

1.14e-0619876660d8d3bbd754ffde41c50013d822667b185a9751
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

NEFL SLC8A1 SLC9A4 ZFHX2 ATP2B1

5.33e-061477658f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCellfacs-Heart-RA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 IRX3 DOCK6 CDH11 NOTCH1

1.21e-0517476542dfb6f42b72e40e203b3ef341117bccf3553d54
ToppCellfacs-Heart-RA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 IRX3 DOCK6 CDH11 NOTCH1

1.21e-05174765f04edf2ca6788875c9918611e416fb739924382e
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND07-28-samps / Age Group, Lineage, Cell class and subclass

FLNB FGD5 DYSF DOCK6 PRX

1.46e-051817659cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLNB FGD5 DYSF DOCK6 NOTCH1

1.54e-05183765bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 SYNPO DOCK6 CDH11 NOTCH1

1.54e-05183765b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNPO FGD5 IRX3 DYSF NOTCH1

1.71e-05187765f2a0d0829dc88aa93bfb2eebbbc0ef156a9cba84
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNPO FGD5 IRX3 DYSF NOTCH1

1.71e-05187765fa71f9220b288ed6a1d06f347fec42649aac1f13
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNPO FGD5 IRX3 DYSF NOTCH1

1.80e-0518976592319bef1f00d6048ba8f9f8b5c6dbb896686b74
ToppCellFetal_29-31_weeks-Endothelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FGD5 DYSF DOCK6 NOTCH1 PRX

2.14e-051967653981f6c7487598f4f7ce4650ac0ac5bd41481d66
ToppCellFetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FGD5 DYSF DOCK6 NOTCH1 PRX

2.20e-051977656a3c647af41fea923311562575a0d656fbc13cbe
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

NEFL SLC8A1 ANK2 TUBA1A KIF3A

2.30e-051997655de2a32bc2e9c752eb19a013b1807949153728fc
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital|World / Primary Cells by Cluster

NEFL SLC8A1 ANK2 TUBA1A ATP2B1

2.36e-052007656bbe8e1f3e91678f1bfb14945365c1578a59a604
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer_Occipital-19|World / Primary Cells by Cluster

NEFL SLC8A1 ANK2 TUBA1A ATP2B1

2.36e-05200765c831d9e0a7178e3634da45548f91fa9e8dc6557c
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma-4|TCGA-Cervix / Sample_Type by Project: Shred V9

ARX ZFHX2 LRRC75A CCDC40

1.02e-04142764369f2e51e0283a4de70e6c7a3b95672c0838f205
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Thalamus / BrainAtlas - Mouse McCarroll V32

ARX SYT2 CCKAR CDH18

1.20e-04148764afebb64365c94b9476494bffe7c364677f19c8cf
ToppCellThalamus-Neuronal-Inhibitory|Thalamus / BrainAtlas - Mouse McCarroll V32

ARX SYT2 CCKAR CDH18

1.20e-041487645f82e5ecacfd223020b8ee975c17d68c1fe6db38
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-3|TCGA-Adrenal / Sample_Type by Project: Shred V9

TBC1D30 DYSF DOCK6 NOTCH1

1.66e-0416176452239a887799362256ecd7e740b716b88ed59a62
ToppCellnormal_Lymph_Node-B_lymphocytes-Undetermined|normal_Lymph_Node / Location, Cell class and cell subclass

TUBA1A SYT2 ATP2B1 CCDC40

1.70e-0416276491ac35ae7fde411cd6a44e715a33dac62419cab8
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AMBP TBC1D30 ARX SYT2

2.04e-0417076402f0be0aab8ba2d35a83238609352ef3677511c9
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ2A AKNA ZFHX2 APOBR

2.18e-04173764c31076c725f4cd912c56903592a2d9356ae59f54
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNB APBA1 SYNPO DYSF

2.18e-04173764b0ff9808e38cb64a734ced498cd0546728746cd5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EHBP1L1 APBA1 AKNA APOBR

2.18e-0417376473f858f2c45d19b9ec8d99ac02c91551790f670c
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BAZ2A AKNA ZFHX2 APOBR

2.18e-04173764a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCelldroplet-Heart-4Chambers-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB FGD5 DOCK6 CDH11

2.18e-041737649a04271c51fae34f547db3206f9ff5857686e45c
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

MXRA5 ANK2 SYNPO RCOR2

2.33e-04176764bfa1633e1b7a8a2f04d37fa07284fe9bc0199f46
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNB APBA1 FGD5 ATP2B1

2.33e-0417676427e6b3ae41068d6cfdda3d46da7df2a27567140e
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNB APBA1 FGD5 ATP2B1

2.33e-04176764d6a5470af9592f34a741265f2ea9651c05c3add3
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MXRA5 ANK2 SYNPO RCOR2

2.38e-041777643d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ALMS1 ZBTB47 SYNPO RUSC2

2.43e-041787649d575902d3dbe33437c9d4200df093a741269803
ToppCell390C-Endothelial_cells-Endothelial-E-|390C / Donor, Lineage, Cell class and subclass (all cells)

FGD5 DYSF DOCK6 PRX

2.43e-04178764804ac3725c1f88e2212172bfb9aa01d97a735621
ToppCell390C-Endothelial_cells-Endothelial-E|390C / Donor, Lineage, Cell class and subclass (all cells)

FGD5 DYSF DOCK6 PRX

2.43e-04178764ad6dc4a375664c919bd48c35c48a561fc5a7de8c
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

TUBA1B SLC9A4 TUBA1A ARX

2.49e-04179764d95367d689732ab2653e8d70d8d8e5eb15ae6eef
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLNB SYNPO FGD5 DOCK6

2.49e-041797641ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell(05)_Ciliated-(4)_1wkpi|(05)_Ciliated / shred by cell type and Timepoint

TUBA1B TUBA1A ACBD6 ANAPC7

2.54e-0418076485fc9b164147b28545e2397d32302eea03ef6346
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FGD5 DYSF DOCK6 PRX

2.54e-04180764d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCellILEUM-non-inflamed-(3)_DC1|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TUBA1B SYT2 APOBR NOTCH1

2.59e-04181764c9f53720249c8569598cc859e43e35c5f3f8475a
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEFL TUBA1A ARX APBA1

2.65e-04182764398ce074a04f6482470b488f1affae4af7d2ec58
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TUBA1A WRNIP1 SYNPO CDH18

2.70e-041837644060d979948e1dd7507977629a7fbdfa4ca65bb6
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNB FGD5 ATP2B1 NOTCH1

2.70e-041837643427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCellwk_20-22-Mesenchymal-Chondrocyte-intermediate_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ACAN SYNPO SLC24A1 RUSC2

2.70e-041837641464b5c4425e8776c4aeb4d2b560481d4bf13931
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAP1GAP TMEM190 TUBA1A ARX

2.70e-0418376449f3ddc1c7c04b4ca837dbd6dad995add82941d6
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TUBA1A WRNIP1 SYNPO CDH18

2.70e-041837640d44a978221cf3f733704bf11863502805fba733
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK2 CDH11 LRRC73 RUSC2

2.82e-041857649faa35ceb89ccd2979072286f063687c9f846ce3
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APBA1 SYNPO FGD5 DOCK6

2.82e-04185764f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D231|Adult / Lineage, Cell type, age group and donor

FGD5 DYSF DOCK6 PRX

2.82e-0418576407f9f38f0739d7c830641723a38385550ac1ac92
ToppCelldroplet-Heart-nan-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGD5 DYSF CDH11 NOTCH1

2.82e-04185764a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCellControl-Endothelial_cells-Endothelial_cells_(other)|Control / group, cell type (main and fine annotations)

FGD5 DYSF DOCK6 PRX

2.88e-04186764c6075fe84226b370c5139066793844ad33ae2db1
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGD5 HNRNPUL1 DOCK6 CDH11

2.88e-041867640ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCelldroplet-Marrow-BM-30m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB TUBA1A APBA1 ATP2B1

2.88e-04186764bcb3ac9f9b51346e0a2b0bda96d149b3c11f7883
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ERCC6 APBA1 ZBTB47 LRRC75A

2.88e-041867645cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

FLNB FGD5 DOCK6 CDH11

2.94e-041877647876dcb4800c2e54874df3d933efb79307a64a97
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D175|Adult / Lineage, Cell type, age group and donor

FGD5 DYSF DOCK6 PRX

2.94e-04187764f3548817f2fded5978137bb252cb628ac199e4f6
ToppCellfacs-Heart-RA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX3 DOCK6 CDH11 NOTCH1

3.00e-041887644ddb11a90bf3baa7237bde304db44dfcc56aed52
ToppCell(04)_Pre-ciliated-(3)_72hpi|(04)_Pre-ciliated / shred by cell type and Timepoint

TUBA1B EHBP1L1 TUBA1A CCDC40

3.00e-04188764f911dc61b008b60aaa2a1e9354085f480a669e2c
ToppCellfacs-Heart-RA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRX3 DOCK6 CDH11 NOTCH1

3.00e-04188764e47e66906922d5c69b1aafe28face0787d3fc563
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MXRA5 IRX3 DOCK6 CDH11

3.00e-04188764ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNPO IRX3 NOTCH1 TMEM88B

3.06e-04189764965e0e388251e7318f8b463816dc96ccb4658677
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

FLNB FGD5 DOCK6 CDH11

3.06e-04189764c81787a8c662db5d7814c583dd64562857629e81
ToppCellLPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGD5 DYSF DOCK6 PRX

3.06e-04189764e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NEFL SLC8A1 ATP2B1 CDH18

3.12e-04190764d594da827e3c16644952b9589cc12b947ce36279
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB FGD5 DYSF NOTCH1

3.12e-0419076438a815abf0ac5cac6071737cadc54a514f62d37d
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGD5 DYSF DOCK6 PRX

3.12e-04190764a3c6eec6df052105ab78b7e3c78f94218d5912eb
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB FGD5 DYSF NOTCH1

3.12e-04190764bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB FGD5 DYSF NOTCH1

3.12e-04190764d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCellwk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FLNB ANK2 TMEM190 ARX

3.12e-04190764b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCelldroplet-Kidney-nan-3m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBA1A FGD5 IRX3 DYSF

3.18e-04191764dc58d45fafd224d2761aefbe0ce79f66b50c1c03
ToppCellILEUM-inflamed-(3)_DC1|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TUBA1B SLC8A1 SYT2 APOBR

3.18e-04191764e77a6cace0d5a0463ad770e1b73fabbcb6f2d45f
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APBA1 SYNPO FGD5 DOCK6

3.18e-04191764b9ae5af426e7a1f2652a47700bb168371bd2dec6
ToppCellASK452-Immune-Mast_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

TUBA1B TUBA1A CTR9 KIF3A

3.24e-041927648269b88ff6073a908f547fcc7c5941f2e8289694
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ERCC6 CTR9 CDK11B APOBR

3.24e-04192764fcdb2e924800457d21e4aaeeedd81dbf80216eed
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGD5 DYSF DOCK6 PRX

3.24e-0419276404f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBA1A FGD5 IRX3 DYSF

3.24e-041927641a2dd398141069ef6ad2f6bb4bae0bac1c6b98e8
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGD5 DYSF DOCK6 PRX

3.24e-04192764c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBA1A FGD5 IRX3 DYSF

3.24e-041927645dd206adb8b84c374ee931f7df2a8b8cf040efab
ToppCelldroplet-Kidney-nan-3m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBA1A FGD5 IRX3 DYSF

3.24e-0419276485be54c2cba8eab4c6ef2a85a526f7a9db4cfe73
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBA1A FGD5 IRX3 DYSF

3.24e-0419276431a9142d97b690992aabee1a181650deb1a44253
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NEFL SLC8A1 ATP2B1 CDH18

3.24e-041927645c7e8b80b44d9ce55c797cdf8267ac5382e26cac
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FGD5 DYSF DOCK6 PRX

3.31e-04193764f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLNB FGD5 DYSF DOCK6

3.31e-04193764e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB SLC8A1 SLC9A4 RAP1GAP

3.31e-04193764536b277d90070c4571c592a3c6323b4bf4819f67
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB SLC8A1 SLC9A4 RAP1GAP

3.31e-041937640499611c21d283321ef6dd24add154dea48da1b7
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGD5 DYSF DOCK6 PRX

3.31e-0419376402f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLNB FGD5 DYSF DOCK6

3.31e-041937646e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLNB FGD5 DYSF DOCK6

3.31e-04193764af5108260783e69a7d67896c5bf64f862525926d
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)|Adult / Lineage, Cell type, age group and donor

FGD5 DYSF DOCK6 PRX

3.31e-0419376439c6c96a2a100b1b290a779d36cc6bc17245720b
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGD5 DYSF DOCK6 PRX

3.31e-041937645122b1ffba42de190061be34ecdc6176f84e56a3
ToppCelldroplet-Kidney-nan-21m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUBA1A FGD5 IRX3 DYSF

3.31e-041937640e39b6c8e7382e61a9891f6c7e3df2a859788219
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ACAN XPC CDK11B KAT14

3.37e-0419476440c6e17e9e48d4fa6da3a0a1066c4c6565a1e096
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGD5 DYSF DOCK6 PRX

3.37e-0419476443f92b0533e26633dc94cce554045d641ef8fd76
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLNB FGD5 DYSF DOCK6

3.37e-041947640b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGD5 DYSF DOCK6 PRX

3.37e-041947641d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGD5 DYSF DOCK6 PRX

3.37e-0419476458f069efdefa0366033764446b9d6ffd4a17807e
ToppCellTCGA-Blood_and_Bone_Marrow-Primary_Tumor-Diffuse_large_B-cell_lymphoma-DLBCL-1|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9

MXRA5 ANK2 SYNPO CDH11

3.37e-04194764eaeeb84576270cc3fc59002ba33bff9639bb0b02
Drugnorkurarinol

ERCC6 XPC

1.10e-052762ctd:C572712
Drugkurarinone

ERCC6 XPC

1.10e-052762ctd:C411319
Drugascaridole

ERCC6 XPC

1.10e-052762ctd:C043372
DrugCarbazoles

ERCC6 XPC

1.10e-052762ctd:D002227
Drugazotochelin

ERCC6 PGBD3

1.10e-052762CID000193592
Drug0175029-0000 [211245-78-2]; Down 200; 1uM; MCF7; HT_HG-U133A

ALMS1 TBC1D30 TECPR2 KRI1 PAGR1 SLC24A1

4.08e-051897664716_DN
DrugDiethylcarbamazine citrate [1642-54-2]; Up 200; 10.2uM; HL60; HT_HG-U133A

MXRA5 ERCC6 ZFHX2 QSER1 SLC24A1 DOCK6

4.86e-051957662394_UP
DrugTorsemide [56211-40-6]; Down 200; 11.4uM; MCF7; HT_HG-U133A

ERCC6 TBC1D30 WBP4 QSER1 ZFX RUSC2

5.00e-051967663517_DN
DrugAmprolium hydrochloride [137-88-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A

BAZ2A ACAN ZFHX2 CDH11 ZFX RUSC2

5.00e-051967664825_UP
DrugProgesterone [57-83-0]; Up 200; 12.8uM; MCF7; HT_HG-U133A

MXRA5 BAZ2A ACAN SYNPO SLC24A1 CCKAR

5.14e-051977664992_UP
Drug(+,-)-Synephrine [94-07-5]; Up 200; 24uM; MCF7; HT_HG-U133A

EHBP1L1 ACAN DYSF SLC24A1 PRX RUSC2

5.14e-051977666798_UP
DrugHydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; PC3; HT_HG-U133A

ANK2 TBC1D30 BAZ2A ACAN SYT2 SLC24A1

5.29e-051987666651_UP
DrugMifepristone [84371-65-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A

MXRA5 TECPR2 SYT2 APOBR CCKAR RUSC2

5.29e-051987663185_UP
Drugestradiol, USP; Up 200; 0.01uM; PC3; HG-U133A

BAZ2A ACAN XPC NOTCH1 ZFX KIF3A

5.29e-05198766665_UP
DrugN-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; PC3; HT_HG-U133A

ANK2 TBC1D30 WRNIP1 SYT2 APOBR CCKAR

5.44e-051997664311_UP
Drugmethylglucamine

SCN8A SLC24A1 ATP2B1 CCKAR

5.52e-0562764CID000004049
Drughaloperidol; Up 200; 10uM; HL60; HT_HG-U133A

FLNB RAP1GAP ERCC6 TECPR2 WBP4 RUSC2

5.59e-052007661144_UP
Drug2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE

TUBA1B TUBA1A

6.57e-054762DB07574
Drug4-NA

SLC8A1 SLC24A1

6.57e-054762CID006102690
Diseaselissencephaly (implicated_via_orthology)

TUBA1B TUBA1A ARX

3.75e-0527713DOID:0050453 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

FLNB RAP1GAP ERCC6 ANK2 RPS6KB2 WBP4 FGD5 DYSF RNF115 NOTCH1 PGBD3

4.89e-0510747111C0006142
DiseaseAdams Oliver syndrome

DOCK6 NOTCH1

8.51e-056712C0265268
DiseaseAdams-Oliver syndrome 1

DOCK6 NOTCH1

8.51e-056712C4551482
DiseaseMalformation of cortical development

TUBA1A ARX

8.51e-056712cv:C1955869
DiseaseLissencephaly

TUBA1A ARX

8.51e-056712cv:C0266463
DiseaseCongenital defect of skull and scalp

DOCK6 NOTCH1

8.51e-056712C2931779
DiseaseAdams-Oliver syndrome (is_implicated_in)

DOCK6 NOTCH1

8.51e-056712DOID:0060227 (is_implicated_in)
Diseasemicrolissencephaly (implicated_via_orthology)

TUBA1B TUBA1A

1.58e-048712DOID:0112234 (implicated_via_orthology)
Diseaselissencephaly 3 (implicated_via_orthology)

TUBA1B TUBA1A

1.58e-048712DOID:0112232 (implicated_via_orthology)
Diseasepolymicrogyria (implicated_via_orthology)

TUBA1B TUBA1A

1.58e-048712DOID:0080918 (implicated_via_orthology)
Diseaseearly infantile epileptic encephalopathy (implicated_via_orthology)

ARX SCN8A

3.10e-0411712DOID:0050709 (implicated_via_orthology)
Diseasetransient cerebral ischemia (biomarker_via_orthology)

NEFL ERCC6 ANK2 NOTCH1

5.68e-04157714DOID:224 (biomarker_via_orthology)
DiseaseCarcinoma of lung

MXRA5 ERCC6

1.40e-0323712C0684249
DiseasePseudoaphakia

ERCC6 ATP2B1

1.52e-0324712C0524524
DiseaseLens Opacities

ERCC6 ATP2B1

1.52e-0324712C1510497
Diseaseobesity (implicated_via_orthology)

ALMS1 ZFHX2 NOTCH1 CCKAR

1.82e-03215714DOID:9970 (implicated_via_orthology)
Diseasecorpus callosum central volume measurement

SLC9A4 TMEM190

2.07e-0328712EFO_0010296
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

ALMS1 RPS6KB2 CCKAR

2.10e-03105713DOID:9352 (implicated_via_orthology)
Diseasecongestive heart failure (biomarker_via_orthology)

SLC8A1 ACAN SCN8A

2.22e-03107713DOID:6000 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
EEEGSGGGQLVTEVT

AMBP

211

P02760
EEITGEGLTASGSGD

BAZ2A

526

Q9UIF9
EEEGVSESEDGGGSS

ALMS1

2461

Q8TCU4
SGESEEAEEEVGEGT

CDK11B

381

P21127
ARGEVGEEEEGGTTG

CCKAR

396

P32238
GEEEEGGTTGASLSR

CCKAR

401

P32238
GGELSSGDDSGEVEF

ACBD6

16

Q9BR61
DEVEGAEADLSGDGT

ERCC6

386

Q03468
LCGEVSVGEEEGEGE

ATP2B1

136

P20020
SVGEEEGEGETGWIE

ATP2B1

141

P20020
EGTEGEATEGLEGTE

AKAP8L

306

Q9ULX6
DSDELEEGRGGVSEG

RCOR2

201

Q8IZ40
EGGREETEREGSGGE

PAGR1

51

Q9BTK6
ETEREGSGGEEAQGE

PAGR1

56

Q9BTK6
AIEGFTDEEDTESGG

QSER1

1336

Q2KHR3
GDSSEGGTLARGEEE

QSOX2

576

Q6ZRP7
AGLEDGVSGEISDTE

PARN

576

O95453
MEGSGEEGDLEGSDS

ANAPC7

536

Q9UJX3
SDEEGDDTMTGDGGE

ANK2

846

Q01484
DEVEGAEADLSGDGT

ERCC6

386

P0DP91
SGGGLETGNSEEEED

NOTCH1

1891

P46531
MPGEEGETAGEGETE

SLC24A1

756

O60721
GETAGEGETEEKSGG

SLC24A1

761

O60721
GSGEEVREGTVGQED

LRRC75A

306

Q8NAA5
TEDAGEGGLDLAIEG

FLNB

1846

O75369
TSTSEGLEEGEVEGE

KAT14

21

Q9H8E8
EEGCEEATGVTGGEQ

FGD5

276

Q6ZNL6
EAEAGGSGDLETETE

EHBP1L1

561

Q8N3D4
GSGDLETETEVVGLE

EHBP1L1

566

Q8N3D4
SEDEDGAGEGGSSLL

KRI1

171

Q8N9T8
QGSGSEEEEAAGTEG

MED17

51

Q9NVC6
EGEEISGSDISGSEE

KIF3A

376

Q9Y496
GGEGLETSASEVGTD

ACAN

1551

P16112
SDERGTLGGFGSVEE

HTATSF1

721

O43719
LDSDTEGEGDIAGTI

DOCK6

1196

Q96HP0
EGDEVGTGITDDNED

INTS14

281

Q96SY0
EGEVETEGEAAVEGE

CCDC40

66

Q4G0X9
SGSEQEGEDEEGGER

CTR9

941

Q6PD62
EGGGEEDTEAFDIAT

CDH11

666

P55287
DGTLGSLEVEEAGES

AKNA

126

Q7Z591
EEEEEGGGDSLEVDG

AKNA

786

Q7Z591
GSAEVEVTDEAAGGE

APBA1

6

Q02410
AAGGGTGTEDDEEEL

ARX

216

Q96QS3
EGGGEEDTEAFDITA

CDH18

661

Q13634
SEDSEEEGLGGLTLE

SBK2

16

P0C263
VADTGGEEDTEDQGL

DYSF

151

O75923
NEEVETEGGSELEGT

HNRNPUL1

61

Q9BUJ2
EELGGEEEDTGGEGL

IRX3

231

P78415
PVSDEESGDEEGGTI

PGBD3

36

Q8N328
GVGASEGGEEEEEEE

RUSC2

1231

Q8N2Y8
RSGGGTEGEQEMEEE

RSPH6A

281

Q9H0K4
ETGLTEGEGEGEEEK

SYT2

121

Q8N9I0
GLVVGGGQEEEEEEE

RGL2

36

O15211
IEEVTDDSSFLGGGG

RNF115

46

Q9Y4L5
DLDLETEEGSEGEGE

RPS6KB2

6

Q9UBS0
EAEESSGEEGLQGEV

SYNPO

36

Q8N3V7
ETEGVDGEDTGLESV

RAP1GAP

581

P47736
EEGESGGESEGKASL

SLC9A4

756

Q6AI14
TDEEAGESGGEGIFR

PRR12

1561

Q9ULL5
EEGSGDEDSEGLGLE

AATF

101

Q9NY61
GGEEAETASGGEEAE

APOBR

306

Q0VD83
GEEAETASGGEEAGT

APOBR

316

Q0VD83
DGDLITVEFDDGDTG

TNRC18

2256

O15417
SREGGEESGGENETD

TTC30B

141

Q8N4P2
ESRDVEGGTEGEGTE

TMEM190

151

Q8WZ59
EGGTEGEGTEEGEET

TMEM190

156

Q8WZ59
GEGTEEGEETEGEEE

TMEM190

161

Q8WZ59
EGEAGEVDELLTGST

ZFHX2

2426

Q9C0A1
GEVELSEGEDDTDGL

TONSL

486

Q96HA7
SSGQGGEELEDEDVE

STYXL2

376

Q5VZP5
EEEEEEGSGEGASGR

PRX

1356

Q9BXM0
GEQEAEEGGVSTETE

WBP4

231

O75554
GTVSEDAIEEEGEEG

SCN8A

456

Q9UQD0
REDVGGSDVTGLGDE

TECPR2

586

O15040
GGGGEARLESQEEET

TBC1D30

21

Q9Y2I9
EGDLEGTSGSDGNVE

RHOXF2

91

Q9BQY4
MSEQGRETEEEEGGG

TMEM88B

1

A6NKF7
RETEEEEGGGGASDT

TMEM88B

6

A6NKF7
EGGEELEEELGGSGT

ZBTB47

211

Q9UFB7
GEEGDDGGETESRES

WRNIP1

96

Q96S55
GEDDLGGTVDIVESE

ZFX

261

P17010
GVDSVEGEGEEEGEE

TUBA1A

436

Q71U36
TDAGGGLSSDEEEGT

XPC

876

Q01831
GVDSVEGEGEEEGEE

TUBA1B

436

P68363
EGEEEEEVAGGAGDT

LRRC73

256

Q5JTD7
TIEGTARGGGEDFED

SLC8A1

576

P32418
VEDEGGSGMGDEENT

MXRA5

696

Q9NR99
GGEGEEGEETKEAEE

NEFL

511

P07196