Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	H3K27me3 modified histone binding	TAF1 TAF1L	2.87e-04	5	108	2	GO:0061628
GeneOntologyMolecularFunction	RNA polymerase II core promoter sequence-specific DNA binding	RELA TAF1 TAF1L	3.25e-04	25	108	3	GO:0000979
GeneOntologyMolecularFunction	fatty acid ligase activity	SLC27A6 ACSL3 ACSM5	3.65e-04	26	108	3	GO:0015645
GeneOntologyMolecularFunction	CoA-ligase activity	SLC27A6 ACSL3 ACSM5	4.09e-04	27	108	3	GO:0016405
Domain	TAF_II_230-bd	TAF1 TAF1L	3.13e-05	2	105	2	IPR009067
Domain	TFIID_sub1_DUF3591	TAF1 TAF1L	3.13e-05	2	105	2	IPR022591
Domain	-	TAF1 TAF1L	3.13e-05	2	105	2	1.10.1100.10
Domain	TBP-binding	TAF1 TAF1L	3.13e-05	2	105	2	PF09247
Domain	DUF3591	TAF1 TAF1L	3.13e-05	2	105	2	PF12157
Domain	TAF1_animal	TAF1 TAF1L	3.13e-05	2	105	2	IPR011177
Domain	AMP-binding_CS	SLC27A6 ACSL3 ACSM5	4.09e-04	26	105	3	IPR020845
Domain	AMP_BINDING	SLC27A6 ACSL3 ACSM5	5.11e-04	28	105	3	PS00455
Domain	ZnF_U1	TUT7 ZMAT3 ZMAT1	5.67e-04	29	105	3	SM00451
Domain	Znf_U1	TUT7 ZMAT3 ZMAT1	5.67e-04	29	105	3	IPR003604
Domain	AMP-binding	SLC27A6 ACSL3 ACSM5	6.28e-04	30	105	3	PF00501
Domain	AMP-dep_Synth/Lig	SLC27A6 ACSL3 ACSM5	6.28e-04	30	105	3	IPR000873
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DLG5 PLK2 ARHGEF28 CDC42BPA LSG1 DAPK3 MLXIP ARHGEF16 TJP1 SYDE2 SRGAP1 SVIL IQSEC1 UTRN MACIR	1.07e-07	861	111	15	36931259
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	NRDE2 DLG5 RPL32 CDC42BPA LSG1 PHRF1 HIP1R PACSIN3 RELA SETD2 INTS11 OS9 MPHOSPH8 MPHOSPH10 LAS1L SEC63 TAF1L UTRN KDM1A	2.65e-07	1497	111	19	31527615
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	RPL32 ZC3H8 DLGAP5 PHRF1 MLXIP ACSL3 NCOR2 PPIG SETD2 KANSL2 INTS11 SLTM MPHOSPH8 LAS1L TAF1L MNT KDM1A	7.59e-07	1294	111	17	30804502
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ZEB1 LSG1 DLGAP5 DAPK3 TSC1 CLIP1 NCOR2 TJP1 SVIL IQSEC1 JAKMIP1 SLC4A4 KDM1A BEGAIN	2.47e-06	963	111	14	28671696
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	DLG5 KIZ TUT7 DYNC2I1 TSC1 RELA CNTLN MLXIP CLIP1 PPIG TJP1 SVIL NME7	3.49e-06	853	111	13	28718761
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	RPL32 RCN1 COG3 CLIP1 SETD2 TJP1 SVIL MPHOSPH10 JAKMIP1 SEC63	5.12e-06	503	111	10	36217030
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ZEB1 DLGAP5 PHRF1 CLIP1 ACSL3 NCOR2 PPIG SETD2 KANSL2 SVIL IQSEC1 UNG	7.15e-06	774	111	12	15302935
Pubmed	The intracellular NADH level regulates atrophic nonunion pathogenesis through the CtBP2-p300-Runx2 transcriptional complex.	TCF7 KIZ ELOVL5 RELA UGT8 KDM1A	7.19e-06	144	111	6	30585266
Pubmed	SMRT derepression by the IkappaB kinase alpha: a prerequisite to NF-kappaB transcription and survival.	RELA NCOR2 UBE2D1	8.84e-06	13	111	3	15494311
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	NRDE2 DLG5 CDC42BPA LSG1 ZC3H8 PPIG SETD2 SNRNP48 TJP1 INTS11 SLTM IQSEC1 MPHOSPH8 SEC63	9.32e-06	1082	111	14	38697112
Pubmed	The elevated expression of osteopontin and NF-κB in human aortic aneurysms and its implication.	SPP1 RELA	1.01e-05	2	111	2	22038347
Pubmed	Functional characterization of two novel non-synonymous alterations in CD46 and a Q950H change in factor H found in atypical hemolytic uremic syndrome patients.	CFH CD46	1.01e-05	2	111	2	25733390
Pubmed	The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: evidence from two independent cohorts.	CFH CD46	1.01e-05	2	111	2	15784724
Pubmed	Atypical hemolytic uremic syndrome associated with mutations in complement regulator genes.	CFH CD46	1.01e-05	2	111	2	20865641
Pubmed	Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.	TAF1 TAF1L	1.01e-05	2	111	2	38804708
Pubmed	Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.	TAF1 TAF1L	1.01e-05	2	111	2	22842574
Pubmed	Mutations in genes encoding complement inhibitors CD46 and CFH affect the age at nephritis onset in patients with systemic lupus erythematosus.	CFH CD46	1.01e-05	2	111	2	22171659
Pubmed	Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.	TAF1 TAF1L	1.01e-05	2	111	2	27571988
Pubmed	Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.	TAF1 TAF1L	1.01e-05	2	111	2	34403156
Pubmed	Osteopontin expression correlates with nuclear factor-κB activation and apoptosis downregulation in clear cell renal cell carcinoma.	SPP1 RELA	1.01e-05	2	111	2	21167650
Pubmed	Genetic analysis of CFH and MCP in Egyptian patients with immune-complex proliferative glomerulonephritis.	CFH CD46	1.01e-05	2	111	2	36211394
Pubmed	TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.	TAF1 TAF1L	1.01e-05	2	111	2	10070062
Pubmed	A specific LSD1/KDM1A isoform regulates neuronal differentiation through H3K9 demethylation.	SVIL KDM1A	1.01e-05	2	111	2	25684206
Pubmed	Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS.	CFH CD46	1.01e-05	2	111	2	22153652
Pubmed	Genetic studies into inherited and sporadic hemolytic uremic syndrome.	CFH CD46	1.01e-05	2	111	2	9551389
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZXDC TCF7 ZEB1 NRAP ZC3H8 TUT7 PEG3 ZBTB41 RELA ZMAT3 SLTM MNT	1.10e-05	808	111	12	20412781
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	PIGN DLG5 RPL32 LSG1 TUT7 PACSIN3 DAPK3 TJP1 SRGAP1 SVIL SLMAP SLTM MPHOSPH10 LAS1L SEC63	1.14e-05	1257	111	15	36526897
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	PHRF1 DNAH2 TENM3 CCDC180 BEGAIN	2.06e-05	103	111	5	10819331
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	LSG1 TUT7 DLGAP5 RCN1 DYNC2I1 TSC1 SETD2 TJP1 TOMM34 OS9 SEC63	2.37e-05	733	111	11	34672954
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	LSG1 TUT7 DLGAP5 HIP1R DOCK10 TSC1 ACSL3 NCOR2 INTS11 SLTM IQSEC1 LAS1L NME7 UTRN KDM1A	2.68e-05	1353	111	15	29467282
Pubmed	mTOR activation protects liver from ischemia/reperfusion-induced injury through NF-κB pathway.	TSC1 RELA	3.02e-05	3	111	2	28356345
Pubmed	Insights into hemolytic uremic syndrome: segregation of three independent predisposition factors in a large, multiple affected pedigree.	CFH CD46	3.02e-05	3	111	2	16386793
Pubmed	Osteopontin induces nuclear factor kappa B-mediated promatrix metalloproteinase-2 activation through I kappa B alpha /IKK signaling pathways, and curcumin (diferulolylmethane) down-regulates these pathways.	SPP1 RELA	3.02e-05	3	111	2	12473670
Pubmed	IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300.	RELA NCOR2	3.02e-05	3	111	2	16382138
Pubmed	Differential impact of complement mutations on clinical characteristics in atypical hemolytic uremic syndrome.	CFH CD46	3.02e-05	3	111	2	17599974
Pubmed	Factor H, membrane cofactor protein, and factor I mutations in patients with hemolysis, elevated liver enzymes, and low platelet count syndrome.	CFH CD46	3.02e-05	3	111	2	18658028
Pubmed	Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome.	CFH CD46	3.02e-05	3	111	2	16621965
Pubmed	Bcl2-associated athanogene 4 promotes the invasion and metastasis of gastric cancer cells by activating the PI3K/AKT/NF-κB/ZEB1 axis.	ZEB1 RELA	3.02e-05	3	111	2	34419501
Pubmed	Regulated expression of TAF1 in 1-cell mouse embryos.	TAF1 TAF1L	3.02e-05	3	111	2	16822332
Pubmed	The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth and chemosensitivity under hypoxic conditions.	PLK2 TSC1	3.02e-05	3	111	2	20054236
Pubmed	TAFII55 binding to TAFII250 inhibits its acetyltransferase activity.	TAF1 TAF1L	3.02e-05	3	111	2	11592977
Pubmed	IkappaBalpha and p65 regulate the cytoplasmic shuttling of nuclear corepressors: cross-talk between Notch and NFkappaB pathways.	RELA NCOR2	3.02e-05	3	111	2	12589049
Pubmed	Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.	TAF1 TAF1L	3.02e-05	3	111	2	12217962
Pubmed	TAF7: a possible transcription initiation check-point regulator.	TAF1 TAF1L	3.02e-05	3	111	2	16407123
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	CDC42BPA RCN1 DAPK3 TSC1 RELA ACSL3 NCOR2 TJP1 SVIL INTS11 SLTM UNG UTRN	3.11e-05	1049	111	13	27880917
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	NRDE2 DLG5 CDC42BPA LSG1 TUT7 PEG3 PACSIN3 CLIP1 PPIG TJP1 SVIL INTS11 IQSEC1 LAS1L SEC63	3.12e-05	1371	111	15	36244648
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	NRAP CDC42BPA PEG3 CLIP1 SLMAP OS9 MYOM2 TAF1 UTRN	3.22e-05	497	111	9	23414517
Pubmed	New nomenclature for chromatin-modifying enzymes.	SETD2 TAF1 TAF1L KDM1A	3.41e-05	57	111	4	18022353
Pubmed	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	CFH DAPK3 CD46	3.47e-05	20	111	3	23326517
Pubmed	Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.	PIGN RELA ACSL3 ANKRD13A IQSEC1 SEC63 KDM1A	3.62e-05	283	111	7	21903422
Pubmed	A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.	RCN1 ACSL3 TJP1 SVIL UTRN	3.97e-05	118	111	5	27377895
Pubmed	A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.	CLIP1 NCOR2 SVIL SLMAP	4.18e-05	60	111	4	19075228
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	RPL32 CDC42BPA DLGAP5 TSC1 NCOR2 PPIG SLTM KDM1A	5.43e-05	411	111	8	35182466
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	STAG1 PYROXD1 LSG1 DNAH2 RCN1 TSC1 ZBTB41 RYR2 ACSL3 SNRNP48 TJP1 MPHOSPH8 MYOM2 MPHOSPH10 JAKMIP1	5.54e-05	1442	111	15	35575683
Pubmed	Genetic disorders in complement (regulating) genes in patients with atypical haemolytic uraemic syndrome (aHUS).	CFH CD46	6.03e-05	4	111	2	20106822
Pubmed	miR-16 targets transcriptional corepressor SMRT and modulates NF-kappaB-regulated transactivation of interleukin-8 gene.	RELA NCOR2	6.03e-05	4	111	2	22292036
Pubmed	Three SIBLINGs (small integrin-binding ligand, N-linked glycoproteins) enhance factor H's cofactor activity enabling MCP-like cellular evasion of complement-mediated attack.	CFH SPP1	6.03e-05	4	111	2	11825898
Pubmed	PARP-1 induces EMT in non-small cell lung carcinoma cells via modulating the transcription factors Smad4, p65 and ZEB1.	ZEB1 RELA	6.03e-05	4	111	2	33417952
Pubmed	MSAP is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain.	MLXIP MYLIP	6.03e-05	4	111	2	12826659
Pubmed	Physical and functional interactions between ZIP kinase and UbcH5.	DAPK3 UBE2D1	6.03e-05	4	111	2	18515077
Pubmed	Osteopontin is linked to p65 and MMP-9 expression in pulmonary adenocarcinoma but not in malignant pleural mesothelioma.	SPP1 RELA	6.03e-05	4	111	2	17493236
Pubmed	The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock.	TSC1 TJP1	6.03e-05	4	111	2	32001717
Pubmed	New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3.	CFH CD46	6.03e-05	4	111	2	25188723
Pubmed	CNPY2 inhibits MYLIP-mediated AR protein degradation in prostate cancer cells.	UBE2D1 MYLIP	6.03e-05	4	111	2	29707137
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	RPL32 LSG1 ZC3H8 DLGAP5 RCN1 NCOR2 SLTM MPHOSPH8 MPHOSPH10 LAS1L SEC63 KDM1A	7.81e-05	989	111	12	36424410
Pubmed	Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord.	PHRF1 HIP1R MLXIP	8.75e-05	27	111	3	19026994
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	CNNM2 DLGAP5 CNTLN ACSL3 INTS11 SLMAP UNG LAS1L UTRN	9.58e-05	573	111	9	28330616
Pubmed	MPP8 and SIRT1 crosstalk in E-cadherin gene silencing and epithelial-mesenchymal transition.	ZEB1 MPHOSPH8	1.00e-04	5	111	2	25870236
Pubmed	Involvement of TFIID and USA components in transcriptional activation of the human immunodeficiency virus promoter by NF-kappaB and Sp1.	RELA TAF1	1.00e-04	5	111	2	9584164
Pubmed	Molecular cloning of rat and mouse membrane cofactor protein (MCP, CD46): preferential expression in testis and close linkage between the mouse Mcp and Cr2 genes on distal chromosome 1.	CFH CD46	1.00e-04	5	111	2	9799332
Pubmed	Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles.	TSC1 PDPK2P	1.00e-04	5	111	2	19843540
Pubmed	Distinct functional domains contribute to degradation of the low density lipoprotein receptor (LDLR) by the E3 ubiquitin ligase inducible Degrader of the LDLR (IDOL).	UBE2D1 MYLIP	1.00e-04	5	111	2	21734303
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	PLK2 PACSIN3 RELA MSH5 MLXIP ANKRD13A SETD2 TJP1 IQSEC1 LAS1L MACIR BEGAIN	1.23e-04	1038	111	12	26673895
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	DLG5 RPL32 STAG1 HIP1R RELA CLIP1 MPHOSPH8 MPHOSPH10	1.41e-04	472	111	8	38943005
Pubmed	Silencing mediator of retinoic acid and thyroid hormone receptors, as a novel transcriptional corepressor molecule of activating protein-1, nuclear factor-kappaB, and serum response factor.	RELA NCOR2	1.50e-04	6	111	2	10777532
Pubmed	Heart 6-phosphofructo-2-kinase activation by insulin requires PKB (protein kinase B), but not SGK3 (serum- and glucocorticoid-induced protein kinase 3).	PDPK2P SGK3	1.50e-04	6	111	2	20687898
Pubmed	Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells.	TAF1 TAF1L	1.50e-04	6	111	2	19959467
Pubmed	Impaired peroxisome proliferator-activated receptor gamma function through mutation of a conserved salt bridge (R425C) in familial partial lipodystrophy.	RELA NCOR2	1.50e-04	6	111	2	17312272
Pubmed	Gravity-sensitive signaling drives 3-dimensional formation of multicellular thyroid cancer spheroids.	SPP1 RELA	1.50e-04	6	111	2	22964303
Pubmed	Deficient TSC1/TSC2-complex suppression of SOX9-osteopontin-AKT signalling cascade constrains tumour growth in tuberous sclerosis complex.	SPP1 TSC1	1.50e-04	6	111	2	28013293
Pubmed	Atypical postinfectious glomerulonephritis is associated with abnormalities in the alternative pathway of complement.	CFH CD46	1.50e-04	6	111	2	23235567
Pubmed	A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.	RPL32 PHRF1 TJP1 SLTM MPHOSPH10	1.77e-04	162	111	5	31363146
Pubmed	Human transcription factor protein interaction networks.	RPL32 TCF7 ZEB1 CDC42BPA RCN1 RELA NCOR2 KANSL2 SVIL TAF1 LAS1L TAF1L MNT KDM1A	1.87e-04	1429	111	14	35140242
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	PPIG SLTM MPHOSPH10 TAF1 LAS1L TAF1L KDM1A	1.92e-04	370	111	7	22922362
Pubmed	The tuberous sclerosis complex regulates trafficking of glucose transporters and glucose uptake.	TSC1 CLIP1	2.10e-04	7	111	2	18511518
Pubmed	Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome.	CFH CD46	2.10e-04	7	111	2	20513133
Pubmed	Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome.	CFH CD46	2.10e-04	7	111	2	19861685
Pubmed	The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner.	RPL32 TSC1	2.10e-04	7	111	2	19047368
Pubmed	The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor.	UBE2D1 MYLIP	2.10e-04	7	111	2	21685362
Pubmed	The regulation of the complement system: insights from genetically-engineered mice.	CFH CD46	2.10e-04	7	111	2	12914820
Pubmed	Generation of functional liver organoids on combining hepatocytes and cholangiocytes with hepatobiliary connections ex vivo.	SPP1 TJP1	2.10e-04	7	111	2	34099675
Pubmed	Association of endogenous viral loci with genes encoding murine histocompatibility and lymphocyte differentiation antigens.	CFH SPP1	2.10e-04	7	111	2	6308669
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	CCDC168 RYR2 NCOR2 SRGAP1 OS9	2.10e-04	168	111	5	30631154
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TUT7 PHRF1 ACSL3 TJP1 SLTM MPHOSPH10 LAS1L UTRN KDM1A	2.53e-04	653	111	9	22586326
Pubmed	Identification of novel M phase phosphoproteins by expression cloning.	MPHOSPH8 MPHOSPH10	2.79e-04	8	111	2	8885239
Pubmed	C3 Glomerulopathy	CFH CD46	2.79e-04	8	111	2	20301598
Pubmed	Genetic mapping in the region of the mouse X-inactivation center.	TAF1 TAF1L	2.79e-04	8	111	2	1974879
Pubmed	Lunapark Is a Component of a Ubiquitin Ligase Complex Localized to the Endoplasmic Reticulum Three-way Junctions.	UBE2D1 OS9	2.79e-04	8	111	2	27387505
Pubmed	High-density molecular map of the central span of the mouse X chromosome.	TAF1 TAF1L	2.79e-04	8	111	2	1675191
Pubmed	Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.	TAF1 TAF1L	2.79e-04	8	111	2	2034279
Cytoband	10p11.2	ZEB1 SVIL	1.61e-04	8	111	2	10p11.2
GeneFamily	Acyl-CoA synthetase family	SLC27A6 ACSL3 ACSM5	1.66e-04	26	75	3	40
GeneFamily	Zinc fingers CCCH-type\|Zinc fingers matrin-type	ZMAT3 ZMAT1	1.68e-04	5	75	2	84
GeneFamily	Blood group antigens\|XK related family	XKR6 XKR4	9.12e-04	11	75	2	955
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	CDC42BPA SPP1 PYROXD1 ZC3H8 TUT7 DLGAP5 DOCK10 DYNC2I1 CLIP1 PPIG SLMAP MPHOSPH8 MPHOSPH10 SEC63	6.63e-07	656	110	14	M18979
Coexpression	GSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP	PLK2 TCF7 RNF19A RELA MLXIP MYOM2 PRDM15	5.65e-06	162	110	7	M8243
Coexpression	RAMALHO_STEMNESS_UP	LSG1 RCN1 MSH5 ZMAT3 TJP1 MPHOSPH10 LAS1L	1.95e-05	196	110	7	M9473
Coexpression	GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN	TCF7 KANSL2 SYDE2 SVIL MYLIP CCDC180 ZMAT1	2.02e-05	197	110	7	M8611
Coexpression	RAMALHO_STEMNESS_UP	LSG1 RCN1 MSH5 ZMAT3 TJP1 MPHOSPH10 LAS1L	2.44e-05	203	110	7	MM1017
Coexpression	LAKE_ADULT_KIDNEY_C29_UNKNOWN_NOVEL_PT_CFH_POS_SUBPOPULATION_S2	CFH ZEB1 TENM3 SVIL UTRN	3.16e-05	86	110	5	M39248
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_1000	SLC27A6 SPP1 RNF19A RNF19B RCN1 DOCK10 SGK3 PGAP2 SVIL	5.36e-07	191	107	9	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k4_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_1000	SLC27A6 SPP1 RNF19A RNF19B RCN1 DOCK10	1.45e-05	104	107	6	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_1000
CoexpressionAtlas	dev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_1000	DLG5 SLC27A6 SPP1 RNF19A RNF19B PEG3 RCN1 DOCK10 RYR2 SRGAP1 PGAP2 SLMAP OS9 SLC4A4 UTRN	1.95e-05	837	107	15	gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	CFH SLC27A6 SPP1 RNF19A NEXMIF RNF19B PEG3 RCN1 DOCK10 SGK3 TENM3 PGAP2 SVIL ZMAT1	3.15e-05	768	107	14	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#2_top-relative-expression-ranked_1000	SLC27A6 RNF19B RCN1 DOCK10 ZMAT1	6.65e-05	84	107	5	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k2_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5	ZEB1 DLGAP5 DNAH2 DYNC2I1 CNTLN CLIP1 PPIG KIAA1549L SLMAP SLTM TAF1 MNT	7.84e-05	629	107	12	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlas	dev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_1000	SLC27A6 SPP1 RNF19A RNF19B RCN1 DOCK10 SGK3 ANKRD13A NCOR2 SYDE2 PGAP2 SVIL SLMAP OS9	1.41e-04	884	107	14	gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_1000
CoexpressionAtlas	dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#4_top-relative-expression-ranked_1000	SLC27A6 SPP1 RCN1 DOCK10 SGK3 ANKRD13A NCOR2 PGAP2 SVIL SLMAP	1.42e-04	474	107	10	gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k4_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	KIZ TUT7 DYNC2I1 TSC1 ZBTB41 COG3 CLIP1 ZRSR2P1 PPIG SETD2 SRGAP1 MPHOSPH8 SEC63	1.51e-04	780	107	13	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	NRDE2 ZEB1 TUT7 DYNC2I1 CNTLN PPIG SLTM MPHOSPH8	3.52e-08	197	111	8	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ARHGEF28 DNAH2 CD46 ZMAT3 NBEAL2 SRGAP1	2.19e-07	168	111	7	e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CFH ARHGEF28 XKR4 PTH2R CFAP54 TENM3	4.06e-06	168	111	6	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs\|normal_Pleural_Fluid / Location, Cell class and cell subclass	SPP1 RNF19B PACSIN3 SETD2 CFAP54 KANSL2	5.30e-06	176	111	6	7a74217b7fa1032b918f00a3972dff5fab74671a
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CFH ARHGEF28 XKR4 PTH2R CFAP54 TENM3	5.66e-06	178	111	6	544379f5a6145429762258d426b876bb36c112f5
ToppCell	10x5'v1-week_17-19-Lymphocytic_NK-T_NK-ILC_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CFH DLG5 TCF7 SLC27A6 ZNF404 SYDE2	5.84e-06	179	111	6	d18a520568cf4b031972d3dd7d4d4bd073ac1fea
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	NRAP DAPK3 RYR2 SVIL SLMAP MYOM2	7.97e-06	189	111	6	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PIGN TCF7 ZEB1 RNF19A SETD2 UTRN	8.21e-06	190	111	6	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	NRAP DAPK3 RYR2 SVIL SLMAP MYOM2	8.21e-06	190	111	6	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFH MLXIP CLIP1 RYR2 TENM3 SRGAP1	8.46e-06	191	111	6	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells\|World / Stress and Cell class	PLK2 ZEB1 TJP1 SRGAP1 SVIL MYLIP	9.52e-06	195	111	6	6b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCell	NS-critical-d_16-33-Epithelial-Secretory\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFH CDC42BPA RCN1 PACSIN3 ARHGEF16 SLC4A4	1.01e-05	197	111	6	a72047b7428c0d4aaf016c1ac23dc30919260fd8
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	CDC42BPA DYNC2I1 PPIG TJP1 SLTM UTRN	1.04e-05	198	111	6	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	LV-03._Atrial_Cardiomyocyte\|LV / Chamber and Cluster_Paper	GOLGA8S CCDC168 RYR2 TOMM34 MYOM2	1.27e-05	120	111	5	3b77bd0e3630cdd45001cecf5e47660a90ebc92e
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP5 DOCK10 CD46 XKR6 JAKMIP1	4.21e-05	154	111	5	75eac6970259a6916fcfa6d3400509cfa2d98d9d
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	TCF7 ZEB1 PTH2R ZNF404 KIAA1549L	6.73e-05	170	111	5	fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCell	droplet-Heart-4Chambers-21m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH RYR2 ZRSR2P1 KANSL2 MYOM2	7.52e-05	174	111	5	f098778ea74012861ec74b425e45776a31f67679
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH STAG1 PEG3 RYR2 SLMAP	7.93e-05	176	111	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	PIGN RNF19A CD46 NCOR2 UGT8	8.15e-05	177	111	5	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNNM2 ZEB1 RYR2 SLCO1C1 TJP1	8.37e-05	178	111	5	185b44700f06ec58b3c09c80520502166c965fd6
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZEB1 XKR4 TENM3 SRGAP1 SVIL	8.37e-05	178	111	5	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFH ZEB1 RYR2 ACSL3 SLC4A4	9.29e-05	182	111	5	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGEF28 SPP1 PTH2R UGT8 SLC4A4	9.29e-05	182	111	5	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH XKR4 TENM3 TJP1 SRGAP1	9.53e-05	183	111	5	848fc6dd129150897ee339343e83c645b6e779eb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH XKR4 TENM3 TJP1 SRGAP1	9.53e-05	183	111	5	7c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CFH ZEB1 RYR2 TENM3 SVIL	1.00e-04	185	111	5	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH SLC27A6 XKR4 CFAP54 TENM3	1.00e-04	185	111	5	34fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH XKR4 TENM3 TJP1 SRGAP1	1.00e-04	185	111	5	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZEB1 MLXIP CLIP1 SETD2 UTRN	1.00e-04	185	111	5	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH SLC27A6 XKR4 CFAP54 TENM3	1.00e-04	185	111	5	8816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCell	10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CFH TCF7 CCDC168 SYDE2 SLTM	1.05e-04	187	111	5	f31d865ce2a21bdf64dbe29ee3e4505ab482604a
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	CNNM2 ARHGEF28 DOCK10 RYR2 SVIL	1.08e-04	188	111	5	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SPP1 HIP1R DOCK10 SLCO1C1 UGT8	1.11e-04	189	111	5	784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DAPK3 SYDE2 SVIL SLMAP MACIR	1.14e-04	190	111	5	e102622f05c7f3e1bd8b224ea159d57033793ee0
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SPP1 HIP1R DOCK10 SLCO1C1 UGT8	1.14e-04	190	111	5	ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	XKR6 XKR4 CFAP54 SVIL UGT8	1.16e-04	191	111	5	5a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCell	COVID-19-kidney-TAL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGEF28 SPP1 NEXMIF PTH2R UGT8	1.16e-04	191	111	5	fe55475ce0666ab5122447a813dc2369e24947b8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	XKR6 XKR4 CFAP54 SVIL UGT8	1.16e-04	191	111	5	55ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCell	COVID-19-kidney-Mito-rich_Distal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGEF28 SPP1 NEXMIF PTH2R UGT8	1.16e-04	191	111	5	0965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCell	(210)_NKT_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	DLG5 ARHGEF28 RNF19A MYOM2 SLC4A4	1.19e-04	192	111	5	08dc0c019c594da7b9944db8fd706aa7780e6ae9
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	NRAP RYR2 SVIL SLMAP MYOM2	1.19e-04	192	111	5	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLK2 RPL32 XKR4 TENM3 SVIL	1.19e-04	192	111	5	b2d9cc2a013012b25b458d4dc77be63e1c2144da
ToppCell	(21)_NKT_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	DLG5 ARHGEF28 RNF19A MYOM2 SLC4A4	1.19e-04	192	111	5	b0a573ddde2978485a857b8261ee1ee5ef68ecef
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_3\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PLK2 ZEB1 PTH2R TENM3 SVIL	1.19e-04	192	111	5	d88753b200d9c8da6716222d697ddf0a1548d6c8
ToppCell	(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells\|(1)_Control_(PBS) / Stress and Cell class	ZEB1 TJP1 SRGAP1 SVIL MYLIP	1.19e-04	192	111	5	e16e49b302019474232ef4cc0ff217d33afe34cf
ToppCell	18-Distal-Mesenchymal-Cartilage\|Distal / Age, Tissue, Lineage and Cell class	CFH RPL32 PEG3 TENM3 JAKMIP1	1.22e-04	193	111	5	52f3d1bb8d8ca91ba12439d46392f377928ff8f8
ToppCell	PCW_07-8.5\|World / Celltypes from embryonic and fetal-stage human lung	PLK2 DAPK3 XKR6 TENM3 SVIL	1.25e-04	194	111	5	5759c83308df017f1faae248e9b85388e25254f0
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	NRAP RYR2 SVIL SLMAP MYOM2	1.25e-04	194	111	5	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	NRAP RYR2 SVIL SLMAP MYOM2	1.25e-04	194	111	5	c3535f7cc0076653c72db582047cff053c322397
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	NRAP RYR2 SVIL MYOM2 SLC4A4	1.28e-04	195	111	5	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CFH PEG3 RCN1 KIAA1549L TENM3	1.28e-04	195	111	5	ec12cfb2fce44cc2de4e198ef5af075e626f0329
ToppCell	NS-moderate-d_16-33-Epithelial-Secretory\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFH CDC42BPA RCN1 SRGAP1 SLC4A4	1.31e-04	196	111	5	70384c1da9baed843f414cfd1403ddd586a2db07
ToppCell	COVID-19_Severe-PLT_4\|World / Disease Group and Platelet Clusters	RNF19A TUT7 PPIG MPHOSPH8 MACIR	1.31e-04	196	111	5	ad43efdd4d73b6615f65f06a315b33576e317473
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 RCN1 MLXIP TJP1 MYLIP	1.35e-04	197	111	5	deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 RCN1 MLXIP TJP1 MYLIP	1.35e-04	197	111	5	a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCell	COVID-19_Severe-PLT_4\|COVID-19_Severe / Disease Group and Platelet Clusters	RNF19A TUT7 PPIG MYLIP MACIR	1.38e-04	198	111	5	abfddbee99ef8c7719e6e6f62571e9be030e4acf
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PEG3 XKR6 XKR4 RYR2 KIAA1549L	1.38e-04	198	111	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	facs-Trachea-nan-3m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPA SPP1 PEG3 TENM3 IQSEC1	1.38e-04	198	111	5	71e847e8c24744d6df4a960348ad2ecf310373b4
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 RCN1 MLXIP TJP1 MYLIP	1.38e-04	198	111	5	f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	CDC42BPA RNF19A DYNC2I1 CD46 CLIP1	1.41e-04	199	111	5	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	CDC42BPA DYNC2I1 CD46 CLIP1 PPIG	1.41e-04	199	111	5	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	mild-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TCF7 ZEB1 RNF19A DOCK10 MPHOSPH8	1.41e-04	199	111	5	06c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCell	Sepsis-URO-Lymphocyte-T/NK-CD4+_Tem\|URO / Disease, condition lineage and cell class	CFH RPL32 TCF7 CCDC168 UNG	1.44e-04	200	111	5	8b7bfe6411de9528603481f6e5612cbbb8471cf6
ToppCell	facs-Brain_Non-Myeloid-Hippocampus\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPA HIP1R DOCK10 ACSL3 UGT8	1.44e-04	200	111	5	fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-dn_T\|Int-URO / Disease, condition lineage and cell class	PIGN RNF19A JAKMIP1 NME7 CCDC180	1.44e-04	200	111	5	020439d9e70fff7246650ab0e9105236688c3ec3
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-MAIT\|Int-URO / Disease, condition lineage and cell class	CFH PACSIN3 UNG JAKMIP1 SLC4A4	1.44e-04	200	111	5	043c18e79a969e37bbff86443e553ac09fe33f84
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGEF28 XKR6 ACSL3 SRGAP1 SVIL	1.44e-04	200	111	5	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-MAIT\|Leuk-UTI / Disease, condition lineage and cell class	CFH CNNM2 XKR6 ZNF404 SLC4A4	1.44e-04	200	111	5	7e0d0f051c197c2c70080f039e1c4dd68db8e74f
Disease	atypical hemolytic-uremic syndrome (is_marker_for)	CFH CD46	3.75e-05	3	105	2	DOID:0080301 (is_marker_for)
Disease	isochorismatase domain-containing protein 1 measurement	CFH SLC27A6	7.49e-05	4	105	2	EFO_0801735
Disease	HELLP Syndrome	CFH CD46	7.49e-05	4	105	2	C0162739
Disease	serum gamma-glutamyl transferase measurement	DLG5 ZEB1 CDC42BPA STAG1 RYR2 NCOR2 SETD2 TJP1 NBEAL2 SVIL JAKMIP1 KDM1A	1.01e-04	914	105	12	EFO_0004532
Disease	hemolytic-uremic syndrome (is_implicated_in)	CFH CD46	1.86e-04	6	105	2	DOID:12554 (is_implicated_in)
Disease	atypical hemolytic-uremic syndrome (is_implicated_in)	CFH CD46	3.46e-04	8	105	2	DOID:0080301 (is_implicated_in)
Disease	Prostatic Cancer, Castration-Resistant	CD46 KDM1A	4.44e-04	9	105	2	C3658266
Disease	Prostatic Neoplasms, Castration-Resistant	CD46 KDM1A	4.44e-04	9	105	2	C3658267
Disease	C3 glomerulopathy	CFH CD46	4.44e-04	9	105	2	C4087273
Disease	Atypical hemolytic-uremic syndrome	CFH CD46	4.44e-04	9	105	2	cv:C2931788
Disease	Hemolytic-uremic syndrome	CFH CD46	4.44e-04	9	105	2	cv:C0019061
Disease	Atypical Hemolytic Uremic Syndrome	CFH CD46	5.54e-04	10	105	2	C2931788
Disease	Diabetic Cardiomyopathies	SPP1 RYR2	6.76e-04	11	105	2	C0853897
Disease	hemopexin measurement	CFH ZBTB41	6.76e-04	11	105	2	EFO_0008149
Disease	T-cell surface glycoprotein CD3 epsilon chain measurement	CFH NME7	9.54e-04	13	105	2	EFO_0802114
Disease	complement factor H-related protein 1 measurement	CFH ZBTB41 KIAA1549L	1.06e-03	56	105	3	EFO_0600054
Disease	amyloid-beta measurement, Alzheimer's disease biomarker measurement	PIGN MYLIP	1.46e-03	16	105	2	EFO_0005194, EFO_0006514
Disease	Lupus Erythematosus, Systemic	TCF7 SPP1 PHRF1	2.10e-03	71	105	3	C0024141
Disease	coagulation factor measurement	CFH ZBTB41	2.29e-03	20	105	2	EFO_0004634
Disease	QT interval	ARHGEF28 NRAP CDC42BPA SLC27A6 SLC4A4 NME7 MACIR	3.03e-03	534	105	7	EFO_0004682
Disease	Drug toxicity	PLK2 CYP2C8 SPP1	3.39e-03	84	105	3	C0013221
Disease	Adverse reaction to drug	PLK2 CYP2C8 SPP1	3.39e-03	84	105	3	C0041755
Disease	cleft lip	ARHGEF28 CCDC168 ZNF404 NCOR2 SVIL	3.52e-03	284	105	5	EFO_0003959

Protein segments in the cluster

Peptide	Gene	Start	Entry
SYAQKKGSAIDRKRH	UNG	256	P13051
SHKKYKERKERRAQQ	AKAP2	261	Q9Y2D5
EKSKYHNRSIRHSRK	CFAP54	1881	Q96N23
KQEAHLRKEKYSTDA	CNTLN	266	Q9NXG0
YRKTSNKELRHLIEV	ACER1	161	Q8TDN7
KGELRKRLSYTTHKL	BEGAIN	11	Q9BUH8
ERYKAASRALKAISK	ARHGEF16	446	Q5VV41
RSYIREKVKEHQASL	CYP2C8	241	P10632
EKDLKYRLQASRAKS	ACSM5	151	Q6NUN0
KNKKEFDHNSNIRYR	CFH	766	P08603
QRQAEHKRKSYESAL	CCDC180	171	Q9P1Z9
RKKNQKYHERNSRLK	CCDC83	51	Q8IWF9
RHLVYESDKNKDEKL	RCN1	286	Q15293
ETHSHKQSRLYKRKA	SPP1	236	P10451
SELKYLGLDTHSRKK	RLN2	146	P04090
HSRKKRQLYSALANK	RLN2	156	P04090
KHDKYRVETLERSLS	GOLGA8S	271	H3BPF8
KHDKYRVEKLERSLS	GOLGA8F;	66	Q08AF8
YTKERTEEHKDLRKA	ARHGEF28	1016	Q8N1W1
RTEHLTEEEKKRYKA	ANKRD13A	281	Q8IZ07
YDENRKKAEAAHRIL	NCOR2	231	Q9Y618
LTKKHTVSQEDRKSY	PGAP2	166	Q9UHJ9
RRKKKGTYLTDETHR	CD46	371	P15529
GNRNKKEKSRRLYKH	LSG1	641	Q9H089
KKAHALQSELRYKSD	NRAP	1401	Q86VF7
RKEQETALRVYSHLK	INTS11	521	Q5TA45
IQTYNKKGASRRKDH	ELOVL5	251	Q9NYP7
REQTLSKQTYHKEAR	IQSEC1	496	Q6DN90
KHREKSSTREKREKY	DYNC2I1	226	Q8WVS4
KRAHSKSLDYLNLDK	MACIR	161	Q96GV9
TEKKHSRKQVERYFT	NRDE2	211	Q9H7Z3
RLKTTRLKEYTIKSH	DAPK3	296	O43293
RKRYSEKVAIHNADL	DLG5	321	Q8TDM6
YEHYESRKKKKRRSA	PHRF1	1101	Q9P1Y6
KRTSKEVYDHARRAL	MYLIP	316	Q8WY64
RYIQSLKRKEKEYEH	MNT	266	Q99583
AYEYKKRLTLDHEKS	MPHOSPH10	451	O00566
CKKALSHKELYERAR	LAS1L	256	Q9Y4W2
EQRRHTAYISELKAK	JAKMIP1	61	Q96N16
KQKSDIEHYRNKLRL	KIAA1549L	1396	Q6ZVL6
ATSREYAIKILEKRH	PDPK2P	76	Q6A1A2
KKAHTRNQEYLKRFE	KIZ	71	Q2M2Z5
RAKKKYIEHRSNETS	PEG3	936	Q9GZU2
KDKYRNQESKSSHRK	PPIG	641	Q13427
DKAAYRKTKNTIERA	FAM9A	141	Q8IZU1
RTYFKKRLQQHKDED	MLXIP	226	Q9HAP2
AHAILSDSKKRKIYD	DNAJC5G	81	Q8N7S2
SATEARYNKLKEKHS	HIP1R	441	O75146
KHDKYRVEKLERSLS	GOLGA8DP	66	Q0D2H9
KSKHRDLTALCKEYD	KDM1A	481	O60341
KYKDALEETRRANHS	DOCK10	1041	Q96BY6
HYLDSKKDVDRHLKS	COG3	681	Q96JB2
SYRQRAQKLSEIHKD	UGT8	421	Q16880
RKSLSQKENRHKEYE	DLGAP5	26	Q15398
KKRRYLHNRKVEHEA	KANSL2	221	Q9H9L4
STENHRKKKQHRFKY	CCDC168	2176	Q8NDH2
HRLASREAIKRTYDK	DNAH2	496	Q9P225
KLKVEHSREYKQERT	RYR2	831	Q92736
SDEHREKKKRFTVYK	SGK3	21	Q96BR1
KNHRTFLKRTKYDNL	NME7	41	Q9Y5B8
KARYERATSETKTKH	CLIP1	1026	P30622
KRNESKEKYQKRHDS	MPHOSPH8	411	Q99549
SYHAARKDEKTAQTR	PACSIN3	156	Q9UKS6
LSEEKLHYRSARTKE	MSH5	471	O43196
KSSLNYLRQKKERPH	SYDE2	1046	Q5VT97
HCKALRRELKEKEYS	UTRN	2601	P46939
RTKKFIRHQSDRYVK	RPL32	16	P62910
SRYEGRKTSKHKRNL	RNF19B	386	Q6ZMZ0
AKTRSTKDHQQYKKD	SRGAP1	76	Q7Z6B7
HSLESKAERIARYKA	SVIL	96	O95425
TIRKNISKHKYQSRE	TAF1L	1571	Q8IZX4
ETIRKNISKHKYQSR	TAF1	1551	P21675
KLYRHKSSSKALRDE	NEXMIF	1446	Q5QGS0
RKESLKQHVSYKHSR	PRDM15	776	P57071
SSIVREHRQKLRKKY	NBEAL2	1046	Q6ZNJ1
YEKIHGRSKEKERAS	SLTM	576	Q9NWH9
YELFQSKTRHRKFKE	CDC42BPA	1341	Q5VT25
DETAKASKQHRLKRY	OS9	156	Q13438
KRKELKTHYQADIER	ACSL3	701	O95573
DLYTDNRTKKKVAHR	CNNM2	586	Q9H8M5
RRAQAHKALKDYKSS	TOMM34	266	Q15785
ASYHKLLRDSRDDKK	XKR6	336	Q5GH73
KAAYRKELEKNRSHV	TSC1	881	Q92574
SKQYDKACRLKIHLR	ZXDC	336	Q2QGD7
RKIHNRYEGKDVSKH	RNF19A	396	Q9NV58
RYEGKDVSKHKRNLA	RNF19A	401	Q9NV58
KSEAKIAHKRTRYTT	PYROXD1	201	Q8WU10
DKHNYETTAKESLRR	SLMAP	246	Q14BN4
EIEKEASRRYHAKSK	STYXL2	486	Q5VZP5
QRYSTKSNLTVHRKK	ZBTB41	396	Q5SVQ8
KNYVSKHRSFITKRE	SLCO1C1	666	Q9NYB5
ASYQKALRDSRDDKK	XKR4	351	Q5GH76
EEDNLRRVSNHKKYK	SEC63	391	Q9UGP8
SSKLLRQDKKTVHSY	STAG1	1011	Q8WVM7
RTTKTEKIYDDHRKF	TENM3	1781	Q9P273
RPSSRDYKHNIKKVD	PIGN	221	O95427
GHDTRKQYRKLAKST	PTH2R	351	P49190
NYGKKKRRSREKHQE	TCF7	341	P36402
YLTERKKNKSHRDIK	SETD2	1481	Q9BYW2
DRGYKRFTSLKEHIK	ZEB1	176	P37275
HKRNNTREKSYECKE	ZNF404	121	Q494X3
ESRKSARKLYERSHK	TJP1	746	Q07157
ESKQHKSKVSEQRYR	ZMAT3	266	Q9HA38
HKEKKEKERISENYS	SLC4A4	51	Q9Y6R1
DHTYKRNGESERKKS	ZRSR2P1	391	Q15695
KDKARYIDTHNRVSK	PLK2	376	Q9NYY3
RYLCKQSKREGEKDH	SLC27A6	316	Q9Y2P4
KRSKEDKEIHNKYTE	TUT7	1386	Q5VYS8
HRIEEKRKRTYETFK	RELA	296	Q04206
RRQSYRAKNVHITKK	SNRNP48	221	Q6IEG0
IYKSDKEKYNRHARE	UBE2D1	126	P51668
QSKHKRKKSYEDTDL	ZMAT1	556	Q5H9K5
KSSLHRKSRSKDYDV	ZC3H8	61	Q8N5P1
EKKHDKYRVETLERS	GOLGA8CP	261	A6NN73
HLARSQARDKLDKYA	MYOM2	116	P54296