Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

KIF23 VWA8 MYO7B ABCA13 ACSM1 WRN RFC5 DNAH7 DDX3X ABCA6 ASCC3 DHX34 ATP4A DYNC1H1 KIF11

2.33e-0561413815GO:0140657
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

CDK8 PDGFRA CDK19 CSK PIK3C2G GUCY2C CLK1 CLK2 CLK3 BTK CHEK2 TAF1 TAF1L TSSK4 G6PC1 PLK4

3.21e-0570913816GO:0016773
GeneOntologyMolecularFunctionATP hydrolysis activity

KIF23 VWA8 ABCA13 WRN RFC5 DNAH7 DDX3X ABCA6 ASCC3 DHX34 ATP4A DYNC1H1

5.74e-0544113812GO:0016887
GeneOntologyMolecularFunctionprotein kinase activity

CDK8 PDGFRA CDK19 CSK GUCY2C CLK1 CLK2 CLK3 BTK CHEK2 TAF1 TAF1L TSSK4 PLK4

7.23e-0560013814GO:0004672
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

CDK8 PDGFRA CDK19 PARP1 POLR3B CSK PIK3C2G GUCY2C CLK1 CLK2 CLK3 BTK CHEK2 TAF1 TAF1L TSSK4 G6PC1 PLK4

8.33e-0593813818GO:0016772
GeneOntologyMolecularFunctionkinase activity

CDK8 PDGFRA CDK19 CSK PIK3C2G GUCY2C CLK1 CLK2 CLK3 BTK CHEK2 TAF1 TAF1L TSSK4 PLK4

2.65e-0476413815GO:0016301
GeneOntologyMolecularFunctionH3K27me3 modified histone binding

TAF1 TAF1L

4.68e-0451382GO:0061628
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

PDE3B ABHD12B PLCXD2 WRN PIWIL4 PNLDC1 PP2D1 ANKZF1 LPIN2 XRN1 PLCD1 G6PC1 LRRD1 DNASE1L1 SMG6

4.72e-0480713815GO:0016788
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

PDGFRA CSK CLK1 CLK2 CLK3 BTK

5.18e-041451386GO:0004713
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

WRN PIWIL4 PNLDC1 RFC5 ANKZF1 TRMT2B DDX3X POLR3B XRN1 ASCC3 DHX34 DNASE1L1 SMG6

5.41e-0464513813GO:0140640
GeneOntologyMolecularFunctionprotein kinase A binding

AKAP9 CSK SPHKAP CRYBG3

6.94e-04581384GO:0051018
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5C KDM5D

6.98e-0461382GO:0034647
GeneOntologyMolecularFunctionmetalloaminopeptidase activity

ANPEP PEPD AOPEP

7.47e-04261383GO:0070006
GeneOntologyMolecularFunctionDNA helicase activity

WRN RFC5 DDX3X ASCC3

8.93e-04621384GO:0003678
GeneOntologyMolecularFunctionprotein serine kinase activity

CDK8 CDK19 CLK1 CLK2 CLK3 CHEK2 TAF1 TSSK4 PLK4

9.63e-043631389GO:0106310
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

CDK8 CDK19 CLK1 CLK2 CLK3 CHEK2 TAF1 TAF1L TSSK4 PLK4

1.09e-0344613810GO:0004674
GeneOntologyMolecularFunctionnuclease activity

WRN PIWIL4 PNLDC1 ANKZF1 XRN1 DNASE1L1 SMG6

1.14e-032311387GO:0004518
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5C KDM5D

1.29e-0381382GO:0032453
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF23 MYO7B DNAH7 DYNC1H1 KIF11

1.37e-031181385GO:0003774
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF23 DNAH7 DYNC1H1 KIF11

1.41e-03701384GO:0003777
GeneOntologyMolecularFunctionRNA polymerase I general transcription initiation factor activity

TAF1 TAF1L

1.65e-0391382GO:0001181
GeneOntologyMolecularFunction7SK snRNA binding

CCNT1 CCNT2

1.65e-0391382GO:0097322
GeneOntologyMolecularFunctionprotein serine/threonine kinase activator activity

DDX3X CCNT1 CCNT2 GCN1

2.10e-03781384GO:0043539
GeneOntologyCellularComponentnuclear cyclin-dependent protein kinase holoenzyme complex

CDK8 CDK19 CCNT1 CCNT2

5.03e-06181374GO:0019908
GeneOntologyCellularComponentchromosome, telomeric region

CTC1 WRN THOC2 ORC5 PARP1 CHEK2 CBX1 SMG6

2.14e-051761378GO:0000781
GeneOntologyCellularComponentCKM complex

CDK8 CDK19

4.21e-0451372GO:1990508
GeneOntologyCellularComponentchromosomal region

PDS5B CTC1 WRN THOC2 SPC24 ORC5 PARP1 CHEK2 CBX1 SMG6

4.67e-0442113710GO:0098687
GeneOntologyCellularComponentnuclear protein-containing complex

CDK8 OGT CTC1 CDK19 U2AF1L4 RFC5 THOC2 MED15 CCNT1 ORC5 CCNT2 ARNT POLR3B TAF1 ASCC3 TAF1L NR1H4 SMG6 SYMPK XPO7

6.54e-04137713720GO:0140513
GeneOntologyCellularComponentmicrotubule associated complex

KIF23 DNAH7 ACTR1B ACTR1A DYNC1H1 KIF11

6.81e-041611376GO:0005875
GeneOntologyCellularComponentcyclin-dependent protein kinase holoenzyme complex

CDK8 CDK19 CCNT1 CCNT2

6.90e-04611374GO:0000307
GeneOntologyCellularComponentpronucleus

CBX1 TAF1 TAF1L

8.00e-04281373GO:0045120
GeneOntologyCellularComponentpole plasm

PIWIL4 DDX3X TDRD6

8.88e-04291373GO:0045495
GeneOntologyCellularComponentgerm plasm

PIWIL4 DDX3X TDRD6

8.88e-04291373GO:0060293
GeneOntologyCellularComponentP granule

PIWIL4 DDX3X TDRD6

8.88e-04291373GO:0043186
GeneOntologyCellularComponentcentriole

CEP55 ACTR1A CEP295 HERC2 PLK4 PCNT

9.61e-041721376GO:0005814
GeneOntologyCellularComponentmicrotubule organizing center

KIF23 UBR4 WRN DDX3X CEP55 ACTR1B ACTR1A RESF1 AKAP9 CEP295 HERC2 CEP57 PLK4 DYNC1H1 PCNT

1.03e-0391913715GO:0005815
GeneOntologyCellularComponentdynactin complex

ACTR1B ACTR1A

1.16e-0381372GO:0005869
GeneOntologyCellularComponentcyclin/CDK positive transcription elongation factor complex

CCNT1 CCNT2

1.49e-0391372GO:0008024
GeneOntologyCellularComponentcentrosome

KIF23 UBR4 WRN DDX3X CEP55 ACTR1B ACTR1A AKAP9 CEP295 CEP57 PLK4 DYNC1H1 PCNT

1.67e-0377013713GO:0005813
GeneOntologyCellularComponenttransferase complex, transferring phosphorus-containing groups

CDK8 CDK19 CCNT1 CCNT2 POLR3B PIK3C2G TAF1 TAF1L

1.67e-033351378GO:0061695
GeneOntologyCellularComponentnuclear speck

WRN U2AF1L4 APBB1 THOC2 ERBIN PALB2 CLK2 CLK3 ASCC3

2.18e-034311379GO:0016607
GeneOntologyCellularComponentnuclear body

WRN U2AF1L4 APBB1 THOC2 ERBIN PALB2 PARP1 ARNT CLK2 CLK3 CHEK2 CBX1 ASCC3 SYMPK

2.45e-0390313714GO:0016604
MousePhenoabnormal mitosis

PDS5B THOC2 CEP55 PARP1 CEP57 GCN1 PLK4 DYNC1H1 PCNT

6.72e-071281099MP:0004046
DomainARM-type_fold

PDS5B NBEAL1 UBR4 HUWE1 IPO9 PIK3C2G AOPEP DIAPH2 GCN1 TANGO6 SYMPK XPO7

7.13e-0633913612IPR016024
DomainTFIID_sub1_DUF3591

TAF1 TAF1L

5.26e-0521362IPR022591
DomainPACT_coil_coil

AKAP9 PCNT

5.26e-0521362PF10495
DomainTBP-binding

TAF1 TAF1L

5.26e-0521362PF09247
DomainDUF3591

TAF1 TAF1L

5.26e-0521362PF12157
DomainArp1

ACTR1B ACTR1A

5.26e-0521362IPR029909
DomainTAF_II_230-bd

TAF1 TAF1L

5.26e-0521362IPR009067
Domain-

TAF1 TAF1L

5.26e-05213621.10.1100.10
DomainPACT_domain

AKAP9 PCNT

5.26e-0521362IPR019528
DomainTAF1_animal

TAF1 TAF1L

5.26e-0521362IPR011177
DomainAAA

VWA8 ABCA13 RFC5 DNAH7 ABCA6 ASCC3 DYNC1H1

8.92e-051441367SM00382
DomainAAA+_ATPase

VWA8 ABCA13 RFC5 DNAH7 ABCA6 ASCC3 DYNC1H1

8.92e-051441367IPR003593
DomainKinase-like_dom

CDK8 PDGFRA CDK19 CSK PIK3C2G GUCY2C CLK1 CLK2 CLK3 BTK CHEK2 TSSK4 PLK4

1.67e-0454213613IPR011009
DomainProt_kinase_dom

CDK8 PDGFRA CDK19 CSK GUCY2C CLK1 CLK2 CLK3 BTK CHEK2 TSSK4 PLK4

2.44e-0448913612IPR000719
DomainPROTEIN_KINASE_DOM

CDK8 PDGFRA CDK19 CSK GUCY2C CLK1 CLK2 CLK3 BTK CHEK2 TSSK4 PLK4

2.63e-0449313612PS50011
DomainLys_sp_deMease-like_dom

KDM5C KDM5D

3.13e-0441362IPR013637
DomainPLU-1

KDM5C KDM5D

3.13e-0441362PF08429
DomainProtein_kinase_ATP_BS

CDK8 PDGFRA CDK19 CSK CLK1 CLK2 CLK3 BTK TSSK4 PLK4

4.64e-0437913610IPR017441
Domainzf-C5HC2

KDM5C KDM5D

5.19e-0451362PF02928
DomainZnf_C5HC2

KDM5C KDM5D

5.19e-0451362IPR004198
DomainPROTEIN_KINASE_ATP

CDK8 PDGFRA CDK19 CSK CLK1 CLK2 CLK3 BTK CHEK2 TSSK4 PLK4

5.42e-0445913611PS00107
DomainS_TKc

CDK8 PDGFRA CDK19 CLK1 CLK2 CLK3 CHEK2 TSSK4 PLK4

1.28e-033591369SM00220
DomainP-loop_NTPase

KIF23 VWA8 MYO7B ABCA13 WRN RFC5 DNAH7 DDX3X ORC5 SAMD9L ABCA6 ASCC3 DHX34 DYNC1H1 KIF11

1.32e-0384813615IPR027417
DomainCyclin_L/T

CCNT1 CCNT2

1.43e-0381362IPR015429
DomainPkinase

CDK8 CDK19 GUCY2C CLK1 CLK2 CLK3 CHEK2 TSSK4 PLK4

1.92e-033811369PF00069
DomainDEAD/DEAH_box_helicase_dom

WRN DDX3X ASCC3 DHX34

1.98e-03731364IPR011545
DomainDEAD

WRN DDX3X ASCC3 DHX34

1.98e-03731364PF00270
DomainJmjN

KDM5C KDM5D

2.28e-03101362SM00545
DomainJmjN

KDM5C KDM5D

2.28e-03101362PF02375
DomainJMJN

KDM5C KDM5D

2.28e-03101362PS51183
DomainJmjN

KDM5C KDM5D

2.28e-03101362IPR003349
DomainPkinase_Tyr

PDGFRA CSK GUCY2C BTK PLK4

2.54e-031291365PF07714
Domain-

VWA8 MYO7B ABCA13 WRN RFC5 DNAH7 DDX3X ORC5 SAMD9L ABCA6 ASCC3 DHX34 DYNC1H1

3.15e-03746136133.40.50.300
DomainABC_A

ABCA13 ABCA6

3.31e-03121362IPR026082
DomainPeptidase_M1

ANPEP AOPEP

3.31e-03121362IPR001930
DomainSer-Thr/Tyr_kinase_cat_dom

PDGFRA CSK GUCY2C BTK PLK4

3.40e-031381365IPR001245
DomainARM-like

PDS5B HUWE1 IPO9 GCN1 TANGO6 SYMPK XPO7

3.66e-032701367IPR011989
DomainPeptidase_M1_N

ANPEP AOPEP

3.90e-03131362IPR014782
DomainPeptidase_M1

ANPEP AOPEP

3.90e-03131362PF01433
DomainDynein_heavy_chain_D4_dom

DNAH7 DYNC1H1

4.52e-03141362IPR024317
DomainDynein_HC_stalk

DNAH7 DYNC1H1

4.52e-03141362IPR024743
DomainDynein_heavy_dom-2

DNAH7 DYNC1H1

4.52e-03141362IPR013602
DomainDHC_N2

DNAH7 DYNC1H1

4.52e-03141362PF08393
DomainIMPORTIN_B_NT

IPO9 XPO7

4.52e-03141362PS50166
DomainATPase_dyneun-rel_AAA

VWA8 DYNC1H1

4.52e-03141362IPR011704
DomainMT

DNAH7 DYNC1H1

4.52e-03141362PF12777
DomainAAA_8

DNAH7 DYNC1H1

4.52e-03141362PF12780
DomainAAA_5

VWA8 DYNC1H1

4.52e-03141362PF07728
Domain-

WRN PIWIL4 PNLDC1

4.85e-034713633.30.420.10
DomainPROTEIN_KINASE_ST

CDK8 CDK19 CLK1 CLK2 CLK3 CHEK2 TSSK4 PLK4

5.07e-033621368PS00108
DomainDHC_fam

DNAH7 DYNC1H1

5.19e-03151362IPR026983
Domain-

KDM5C KDM5D

5.19e-031513621.10.150.60
DomainBRIGHT

KDM5C KDM5D

5.19e-03151362SM00501
DomainARID_dom

KDM5C KDM5D

5.19e-03151362IPR001606
DomainARID

KDM5C KDM5D

5.19e-03151362PS51011
DomainDynein_heavy

DNAH7 DYNC1H1

5.19e-03151362PF03028
DomainIBN_N

IPO9 XPO7

5.19e-03151362PF03810
DomainARID

KDM5C KDM5D

5.19e-03151362PF01388
DomainDynein_heavy_dom

DNAH7 DYNC1H1

5.19e-03151362IPR004273
DomainPROTEIN_KINASE_TYR

PDGFRA CSK BTK PLK4

5.53e-03971364PS00109
DomainTyr_kinase_AS

PDGFRA CSK BTK PLK4

5.53e-03971364IPR008266
DomainZINC_PROTEASE

ANPEP AOPEP ADAMTS18 MMP13

5.73e-03981364PS00142
DomainIBN_N

IPO9 XPO7

5.91e-03161362SM00913
DomainActin_CS

ACTR1B ACTR1A

5.91e-03161362IPR004001
DomainImportin-beta_N

IPO9 XPO7

6.66e-03171362IPR001494
DomainACTINS_2

ACTR1B ACTR1A

6.66e-03171362PS00432
PathwayREACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE

ACTR1A AKAP9 CEP57 PLK4 DYNC1H1 TCTN2 PCNT

4.55e-0697977M27478
PathwayREACTOME_AURKA_ACTIVATION_BY_TPX2

ACTR1A AKAP9 CEP57 PLK4 DYNC1H1 PCNT

9.84e-0672976M27749
PathwayREACTOME_CELL_CYCLE

PDS5B KIF23 CTC1 WRN RFC5 SPC24 ACTR1A ORC5 AKAP9 LPIN2 CHEK2 HERC2 CEP57 PLK4 DYNC1H1

1.48e-056039715MM14635
PathwayREACTOME_CELL_CYCLE

PDS5B KIF23 CTC1 WRN RFC5 SPC24 ACTR1A ORC5 AKAP9 LPIN2 CHEK2 HERC2 CEP57 PLK4 DYNC1H1 PCNT

1.90e-056949716M543
PathwayWP_DNA_IRDAMAGE_AND_CELLULAR_RESPONSE_VIA_ATR

WRN PALB2 PARP1 CLK2 CHEK2 HERC2

1.94e-0581976M39490
PathwayREACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES

ACTR1A AKAP9 CEP57 PLK4 DYNC1H1 PCNT

1.94e-0581976M748
PathwayREACTOME_REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION

ACTR1A AKAP9 CEP57 PLK4 DYNC1H1 PCNT

2.93e-0587976M27194
PathwayREACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES

ACTR1A AKAP9 CEP57 PLK4 DYNC1H1 PCNT

4.82e-0595976M6729
PathwayREACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE

ACTR1A AKAP9 CEP57 PLK4 DYNC1H1 TCTN2

5.11e-0596976MM15207
PathwayREACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR

WRN APBB1 RFC5 PALB2 PARP1 CHEK2 HERC2

6.53e-05146977MM15292
PathwayREACTOME_MITOTIC_PROMETAPHASE

PDS5B SPC24 ACTR1A AKAP9 CEP57 PLK4 DYNC1H1 PCNT

8.05e-05204978M4217
PathwayREACTOME_AURKA_ACTIVATION_BY_TPX2

ACTR1A AKAP9 CEP57 PLK4 DYNC1H1

1.26e-0471975MM15495
PathwayREACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR

WRN APBB1 RFC5 PALB2 PARP1 CHEK2 HERC2

1.69e-04170977M27582
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER

CDK8 CCNT1 CCNT2 PARP1

1.75e-0441974MM14876
PathwayREACTOME_REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION

ACTR1A AKAP9 CEP57 PLK4 DYNC1H1

2.95e-0485975MM14906
PathwayREACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES

ACTR1A AKAP9 CEP57 PLK4 DYNC1H1

3.85e-0490975MM14979
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER

CDK8 CCNT1 CCNT2 PARP1

4.11e-0451974M665
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATION

WRN RFC5 CHEK2 TAF1 TAF1L

4.26e-0492975MM15338
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATION

WRN RFC5 CHEK2 TAF1 TAF1L

4.26e-0492975M27636
PathwayREACTOME_CELL_CYCLE_MITOTIC

PDS5B KIF23 RFC5 SPC24 ACTR1A ORC5 AKAP9 LPIN2 CEP57 PLK4 DYNC1H1 PCNT

4.57e-045619712M5336
PathwayREACTOME_CILIUM_ASSEMBLY

ACTR1A AKAP9 CEP57 PLK4 DYNC1H1 TCTN2 PCNT

4.69e-04201977M27472
PathwayREACTOME_MITOTIC_PROMETAPHASE

PDS5B SPC24 ACTR1A AKAP9 CEP57 PLK4 DYNC1H1

4.83e-04202977MM15362
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

CDK8 OGT WRN U2AF1L4 RFC5 THOC2 CCNT1 CCNT2 PARP1 ZNF836 ARNT POLR3B CHEK2 TAF1 TAF1L NR1H4 SYMPK

5.55e-0410229717MM15436
PathwayREACTOME_M_PHASE

PDS5B KIF23 SPC24 ACTR1A AKAP9 LPIN2 CEP57 PLK4 DYNC1H1 PCNT

5.84e-044179710M27662
PathwayREACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION

CDK8 CCNT1 CCNT2

7.32e-0426973MM14878
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH7 ACTR1B ACTR1A

8.19e-0427973M47755
PathwayREACTOME_HOMOLOGY_DIRECTED_REPAIR

WRN RFC5 PALB2 PARP1 HERC2

1.22e-03116975MM15294
PathwayREACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION

KIF23 ACTR1B ACTR1A DYNC1H1 KIF11

1.22e-03116975MM14855
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

CDK8 CDK19 MED15 ARNT NR1H4

1.32e-03118975M27316
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

CDK8 CCNT1 CCNT2 PARP1 CHRDL1

1.32e-03118975MM15588
PathwayREACTOME_TRANSCRIPTION_OF_THE_HIV_GENOME

CCNT1 CCNT2 TAF1 TAF1L

1.36e-0370974M27008
PathwayREACTOME_M_PHASE

PDS5B KIF23 SPC24 ACTR1A AKAP9 LPIN2 CEP57 PLK4 DYNC1H1

1.37e-03387979MM15364
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

CDK8 KIF23 OGT MATN2 U2AF1L4 HUWE1 RFC5 THOC2 ERBIN DDX3X MED15 CCNT1 ACTR1A CCNT2 PARP1 ARNT IPO9 AKAP9 XRN1 ASCC3 GCN1 DYNC1H1

5.22e-0912471392227684187
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

CEP55 ACTR1B ACTR1A AKAP9 CEP295 CEP57 PLK4 DYNC1H1 PCNT

8.14e-09146139921399614
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

KIF23 KDM5C UBR4 HUWE1 RFC5 DDX3X PARP1 TAF1 GCN1 DYNC1H1 KIF11 SYMPK

1.06e-083321391232786267
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

OGT UBR4 HUWE1 PALB2 RESF1 XRN1 TAF1 CRYBG3 ASCC3 GCN1 KIF11 TANGO6 PCNT

1.50e-084181391334709266
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

KIF23 ABCA13 UBR4 DDX3X SAMD9L SERPINI2 CLK1 CHEK2 ADAMTS18 CPLANE1 ATP4A KIF11

2.67e-083611391226167880
Pubmed

Defining the membrane proteome of NK cells.

PDE3B PDGFRA UBR4 HUWE1 ANKZF1 CEP55 MED15 ACTR1B PARP1 IPO9 CLK3 XRN1 HERC2 ASCC3 DHX34 IL2RG GCN1 DYNC1H1 KIF11 PCNT

4.55e-0811681392019946888
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

KIF23 OGT APBB1 HUWE1 THOC2 ERBIN CEP55 MED15 XRN1 TAF1 ASCC3 GCN1 DYNC1H1 SYMPK

4.88e-085491391438280479
Pubmed

Characterization of centrosomal proteins Cep55 and pericentrin in intercellular bridges of mouse testes.

KIF23 CEP55 PCNT

6.25e-083139320186884
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PDE3B KIF23 PDGFRA PSD3 APBB1 ERBIN DNAH7 DDX3X MADD IPO9 RESF1 AKAP9 CLK3 XRN1 CRYBG3 PLK4 KIF11

6.88e-088611391736931259
Pubmed

The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion.

ACTR1A AKAP9 CEP57 PLK4 DYNC1H1 PCNT

1.01e-0756139611076968
Pubmed

The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation.

ACTR1A AKAP9 CEP57 PLK4 DYNC1H1 PCNT

1.12e-0757139616462731
Pubmed

Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation.

ACTR1A AKAP9 CEP57 PLK4 DYNC1H1 PCNT

1.25e-0758139612852856
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

OGT RFC5 PARP1 TAF1 TAF1L GCN1 DYNC1H1 KIF11 SYMPK

1.40e-07203139922083510
Pubmed

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.

ACTR1A AKAP9 CEP57 PLK4 DYNC1H1 PCNT

1.69e-076113967790358
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CTNNAL1 PSD3 HUWE1 FAM171B ERBIN MADD CEP55 PARP1 IPO9 AKAP9 CSK SLC39A6 CRYBG3 HERC2 GCN1 PLK4 PCNT SYMPK

2.21e-0710491391827880917
Pubmed

Characterization by cDNA cloning of two new human protein kinases. Evidence by sequence comparison of a new family of mammalian protein kinases.

CLK1 CLK2 CLK3

2.49e-07413937990150
Pubmed

Chromosomal mapping of three human LAMMER protein-kinase-encoding genes.

CLK1 CLK2 CLK3

2.49e-07413939856501
Pubmed

Characterization and comparison of four serine- and arginine-rich (SR) protein kinases.

CLK1 CLK2 CLK3

2.49e-07413939307018
Pubmed

Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.

ACTR1A AKAP9 CEP57 PLK4 DYNC1H1 PCNT

2.73e-0766139612221128
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

CDK8 KIF23 HUWE1 THOC2 ERBIN PALB2 CEP55 MED15 SPC24 ACTR1A IPO9 XRN1 KIF11 PCNT

3.45e-076451391425281560
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

PDS5B KIF23 UBR4 HUWE1 RFC5 ERBIN ACTR1B CCNT1 ACTR1A PARP1 POLR3B IPO9 XRN1 CBX1 HERC2 ASCC3 DHX34 GCN1 DYNC1H1 KIF11

4.75e-0713531392029467282
Pubmed

Human mediator subunit MED26 functions as a docking site for transcription elongation factors.

CDK8 CDK19 MED15 CCNT1 CCNT2 TAF1

4.99e-0773139621729782
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

RFC5 ERBIN CCNT1 CCNT2 PARP1 POLR3B IPO9 TAF1 TAF1L GCN1 KIF11

5.31e-073901391117643375
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CDK8 OGT VWA8 KDM5C RFC5 WDR37 CCNT1 RESF1 XRN1 CBX1 CEP295 TAF1 CRYBG3 ASCC3 DHX34 TSSK4 UNC80 TCTN2

5.43e-0711161391831753913
Pubmed

Cdc2-like kinases and DNA topoisomerase I regulate alternative splicing of tissue factor in human endothelial cells.

CLK1 CLK2 CLK3

6.21e-075139319168442
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

HUWE1 RFC5 LENG9 ACTR1A ORC5 PARP1 IPO9 CSK GCN1 DYNC1H1 KIF11 PCNT SYMPK

6.73e-075821391320467437
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

PDS5B KIF23 OGT ANPEP CTC1 CEP55 SPC24 ACTR1B ACTR1A ORC5 CSK CHEK2 CBX1 ZNF552 HERC2 GCN1 PLK4 DYNC1H1

8.88e-0711551391820360068
Pubmed

Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis.

CEP55 AKAP9 PCNT

1.24e-066139316198290
Pubmed

Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.

PSD3 CCNT1 IPO9 AKAP9 XRN1 HERC2

1.42e-0687139617148452
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

PDS5B KIF23 OGT UBR4 CDK19 PSD3 ACTR1B GCN1 DYNC1H1

1.62e-06272139931010829
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KIF23 OGT UBR4 HUWE1 ERBIN DDX3X ACTR1A PARP1 AKAP9 SPHKAP DIAPH2 HERC2 DYNC1H1 KIF11 PCNT SMG6

1.66e-069631391628671696
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

CTNNAL1 OGT CTC1 HUWE1 CUBN FAM171B THOC2 ERBIN MADD RESF1 AOPEP ADAMTS18 CEP295 CPLANE1 CCDC171 KIF11 PCNT

1.68e-0610841391711544199
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

KIF23 OGT PEPD DDX3X CCNT1 PARP1 ASCC3 GCN1 DYNC1H1 SYMPK

1.89e-063571391037059091
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

CDK8 PDS5B OGT RFC5 THOC2 PALB2 DDX3X MED15 CCNT1 ACTR1A ORC5 CCNT2 PARP1 ARNT RESF1 DYNC1H1 KIF11

2.13e-0611031391734189442
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PDS5B KIF23 UBR4 HUWE1 THOC2 XRN1 HERC2 ASCC3 GCN1 DYNC1H1 PCNT SYMPK XPO7

2.40e-066531391322586326
Pubmed

Mediator complex recruits epigenetic regulators via its two cyclin-dependent kinase subunits to repress transcription of immune response genes.

CDK8 CDK19 MED15

3.45e-068139323749998
Pubmed

Deletion of Prl7d1 causes placental defects at mid-pregnancy in mice.

OGT TAF1 TAF1L

3.45e-068139331012985
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

CDK19 PSD3 ADGRV1 ERBIN GCN1 UNC80 PCNT SMG6

3.69e-06225139812168954
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

CEP55 CCNT1 ACTR1A CCNT2 AKAP9 CSK CLK1 CLK2 CLK3 RIN2 BTK CHEK2 CPLANE1 TAF1L PLK4

3.95e-069101391536736316
Pubmed

The protein interaction landscape of the human CMGC kinase group.

CDK8 PDGFRA CDK19 HUWE1 MED15 CCNT1 CCNT2 AKAP9 CLK1 CLK2 CLK3 CHEK2 HERC2

4.71e-066951391323602568
Pubmed

TFIID component TAF7 functionally interacts with both TFIIH and P-TEFb.

CCNT1 CCNT2 TAF1

5.16e-069139318391197
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PDS5B CDK19 PSD3 ERBIN MADD AKAP9 SPHKAP DYNC1H1 PCNT XPO7

6.02e-064071391012693553
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

OGT WRN RFC5 ANKZF1 ERBIN CEP55 MED15 CCNT1 ACTR1A ORC5 GZF1 CLK3 XRN1 CBX1 HERC2 ASCC3 TAF1L DNASE1L1 SMG6

8.57e-0614971391931527615
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

UBR4 HUWE1 THOC2 DDX3X ACTR1A PARP1 IPO9 ASCC3 GCN1 DYNC1H1 KIF11 SYMPK

1.05e-056381391233239621
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

PDS5B RFC5 THOC2 MED15 CCNT1 CCNT2 POLR3B CBX1 TAF1 HERC2 DYNC1H1

1.06e-055331391130554943
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

PDE3B APBB1 FAM171B ERBIN CEP55 XRN1 CRYBG3 GCN1

1.15e-05263139834702444
Pubmed

A Large-scale genetic association study of esophageal adenocarcinoma risk.

PDGFRA WRN PARP1 ARNT SERPINI2 AKAP9 CSK CHEK2 ASCC3

1.27e-05351139920453000
Pubmed

Insights into the ubiquitin-proteasome system of human embryonic stem cells.

UBR4 ACTR1B ACTR1A CLK2 TAF1 HERC2 TAF1L DYNC1H1

1.36e-05269139829511261
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

HUWE1 AKAP9 HERC2 DYNC1H1 KIF11

1.40e-0576139527542412
Pubmed

Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.

CTNNAL1 APBB1 HUWE1 ERBIN IPO9 CLK3 XRN1 SLC39A6 GCN1 KIF11

1.41e-054491391031732153
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

PDS5B KIF23 OGT KDM5C UBR4 RFC5 THOC2 MED15 CCNT1 CCNT2 PARP1 POLR3B TAF1 SYMPK XPO7

1.42e-0510141391532416067
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

FAT4 KIF23 WRN APBB1 HUWE1 FAM171B ERBIN DNAH7 DDX3X XRN1 GCN1 DYNC1H1 XPO7

1.54e-057771391335844135
Pubmed

Central role for the Werner syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly(ADP-ribosyl)ation pathway after DNA damage.

WRN PARP1

1.59e-052139214612404
Pubmed

Inhibition of Cyclin-Dependent Kinase 8/Cyclin-Dependent Kinase 19 Suppresses Its Pro-Oncogenic Effects in Prostate Cancer.

CDK8 CDK19

1.59e-052139235181333
Pubmed

Regulatory functions of the Mediator kinases CDK8 and CDK19.

CDK8 CDK19

1.59e-052139230585107
Pubmed

PARP-1 regulates mouse embryonic neural stem cell proliferation by regulating PDGFRα expression.

PDGFRA PARP1

1.59e-052139232295715
Pubmed

The Cep57-pericentrin module organizes PCM expansion and centriole engagement.

CEP57 PCNT

1.59e-052139230804344
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5C KDM5D

1.59e-052139210441747
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5C KDM5D

1.59e-052139216416087
Pubmed

HIV Transcription Is Independent of Mediator Kinases.

CDK8 CDK19

1.59e-052139231044597
Pubmed

Chk2 deficiency in Myc overexpressing lymphoma cells elicits a synergistic lethal response in combination with PARP inhibition.

PARP1 CHEK2

1.59e-052139222030621
Pubmed

Beta-centractin: characterization and distribution of a new member of the centractin family of actin-related proteins.

ACTR1B ACTR1A

1.59e-05213927696711
Pubmed

Insight into genetic susceptibility to male breast cancer by multigene panel testing: Results from a multicenter study in Italy.

PALB2 CHEK2

1.59e-052139230613976
Pubmed

Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.

TAF1 TAF1L

1.59e-052139238804708
Pubmed

Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.

KDM5C KDM5D

1.59e-052139232081420
Pubmed

Coding variants in the PCNT and CEP295 genes contribute to breast cancer risk in Chinese women.

CEP295 PCNT

1.59e-052139234418690
Pubmed

Profiling of the genetic features of patients with breast, ovarian, colorectal and extracolonic cancers: Association to CHEK2 and PALB2 germline mutations.

PALB2 CHEK2

1.59e-052139238061684
Pubmed

Cyclin-Dependent Kinases 8 and 19 Regulate Host Cell Metabolism during Dengue Virus Serotype 2 Infection.

CDK8 CDK19

1.59e-052139232560467
Pubmed

Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.

TAF1 TAF1L

1.59e-052139222842574
Pubmed

The role of c-Src in platelet-derived growth factor alpha receptor internalization.

PDGFRA CSK

1.59e-052139214644164
Pubmed

Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.

TAF1 TAF1L

1.59e-052139227571988
Pubmed

Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.

TAF1 TAF1L

1.59e-052139234403156
Pubmed

Clinical utility of testing for PALB2 and CHEK2 c.1100delC in breast and ovarian cancer.

PALB2 CHEK2

1.59e-052139234113003
Pubmed

[Mechanisms of transcriptional regulation upon protein phosphorylation by mediator complexes].

CDK8 CDK19

1.59e-052139220408451
Pubmed

A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.

KDM5C KDM5D

1.59e-05213927524912
Pubmed

Mediator kinase inhibition further activates super-enhancer-associated genes in AML.

CDK8 CDK19

1.59e-052139226416749
Pubmed

Poly(ADP-ribosylation) of P-TEFb by PARP1 disrupts phase separation to inhibit global transcription after DNA damage.

CCNT1 PARP1

1.59e-052139235393539
Pubmed

CDK8/19 Mediator kinases potentiate induction of transcription by NFκB.

CDK8 CDK19

1.59e-052139228855340
Pubmed

Modulation of farnesoid X receptor results in post-translational modification of poly (ADP-ribose) polymerase 1 in the liver.

PARP1 NR1H4

1.59e-052139223178280
Pubmed

Increased frequency of multiradial chromosome structures in mouse embryonic fibroblasts lacking functional Werner syndrome protein and poly(ADP-ribose) polymerase-1.

WRN PARP1

1.59e-052139215642393
Pubmed

Physical and functional interaction of the Werner syndrome protein with poly-ADP ribosyl transferase.

WRN PARP1

1.59e-052139214596914
Pubmed

Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer.

CDK8 CDK19

1.59e-052139227678455
Pubmed

CDK8 and CDK19 regulate intestinal differentiation and homeostasis via the chromatin remodeling complex SWI/SNF.

CDK8 CDK19

1.59e-052139236006697
Pubmed

Poly(ADP-ribose) polymerase 1 promotes oxidative-stress-induced liver cell death via suppressing farnesoid X receptor α.

PARP1 NR1H4

1.59e-052139224043304
Pubmed

CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins.

CDK8 CDK19

1.59e-052139237378433
Pubmed

Pathogenic and likely pathogenic variants in PALB2, CHEK2, and other known breast cancer susceptibility genes among 1054 BRCA-negative Hispanics with breast cancer.

PALB2 CHEK2

1.59e-052139231206626
Pubmed

Differential effect of CLK SR Kinases on HIV-1 gene expression: potential novel targets for therapy.

CLK1 CLK2

1.59e-052139221682887
Pubmed

TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.

TAF1 TAF1L

1.59e-052139210070062
Pubmed

In vivo misregulation of genes involved in apoptosis, development and oxidative stress in mice lacking both functional Werner syndrome protein and poly(ADP-ribose) polymerase-1.

WRN PARP1

1.59e-052139216195394
Pubmed

Csk mediates G-protein-coupled lysophosphatidic acid receptor-induced inhibition of membrane-bound guanylyl cyclase activity.

CSK GUCY2C

1.59e-052139216519534
Pubmed

Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

KDM5C KDM5D

1.59e-05213929060413
Pubmed

Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice.

WRN PARP1

1.59e-052139212707040
Pubmed

The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing.

CLK2 CLK3

1.59e-05213929637771
Pubmed

Identification of target genes for the CDK subunits of the Mediator complex.

CDK8 CDK19

1.59e-052139222117896
Pubmed

Global landscape of HIV-human protein complexes.

UBR4 HUWE1 ANKZF1 CCNT1 IPO9 AKAP9 HERC2 CEP57 DYNC1H1 SMG6

1.64e-054571391022190034
Pubmed

Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.

KDM5C KDM5D PCDH11X

1.74e-0513139314660691
Pubmed

The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus.

TAF1 TAF1L IL2RG

1.74e-051313937805729
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

PDS5B OGT UBR4 WRN HUWE1 RFC5 THOC2 DDX3X CCNT1 PARP1 IPO9 CLK2 BTK CBX1 ASCC3 GCN1 DYNC1H1

2.17e-0513181391730463901
Pubmed

The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.

UBR4 HUWE1 HERC2

2.20e-0514139327626314
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

NBEAL1 UBR4 PEPD LENG9 MADD ACTR1B ACTR1A IPO9 AKAP9 CLK3 TAF1L SYMPK

2.24e-056891391236543142
InteractionMED4 interactions

CDK8 CDK19 HUWE1 THOC2 ERBIN CEP55 MED15 SPC24 ACTR1A POLR3B XRN1 HERC2 KIF11 PCNT

2.43e-0645013714int:MED4
InteractionYWHAH interactions

PDE3B KIF23 OGT PSD3 APBB1 HUWE1 WDR37 ERBIN DNAH7 DDX3X MADD IPO9 RESF1 AKAP9 CSK CLK2 CLK3 XRN1 CRYBG3 PLK4 KIF11 PCNT

5.12e-06110213722int:YWHAH
InteractionTHRAP3 interactions

CDK8 KIF23 OGT ABHD12B MATN2 APBB1 MADD PARP1 CLK1 CLK2 CLK3 CBX1 SMG6

1.06e-0544313713int:THRAP3
InteractionMRC1 interactions

BTK CHEK2 ATP4A

1.68e-0581373int:MRC1
InteractionCLK1 interactions

KIF23 ABCA13 SAMD9L SERPINI2 CLK1 CLK2 CLK3 ATP4A SYMPK

1.93e-052191379int:CLK1
InteractionMLLT1 interactions

CCNT1 CCNT2 PARP1 CLK1 CLK2 CLK3 BTK

2.12e-051231377int:MLLT1
InteractionITGB3 interactions

PDGFRA UBR4 HUWE1 PARP1 IPO9 CSK GCN1 DYNC1H1

2.16e-051701378int:ITGB3
InteractionNIN interactions

KIF23 RFC5 CEP55 SPC24 ACTR1A XRN1 CEP295 HERC2 CPLANE1 DYNC1H1 PCNT

3.52e-0535913711int:NIN
InteractionBIVM-ERCC5 interactions

CLK1 CLK2 CLK3

3.56e-05101373int:BIVM-ERCC5
InteractionHERC2 interactions

CDK8 UBR4 WRN APBB1 DDX3X ARNT AKAP9 CLK2 TAF1 HERC2 TAF1L ATP4A KIF11

4.00e-0550313713int:HERC2
InteractionLYPD3 interactions

PDS5B KIF23 PALB2 ORC5 CHEK2 SYMPK XPO7

5.10e-051411377int:LYPD3
InteractionSAMD9L interactions

SAMD9L CSK CLK1

6.46e-05121373int:SAMD9L
InteractionKDM1A interactions

OGT UBR4 HUWE1 THOC2 PALB2 RESF1 AKAP9 XRN1 CBX1 TAF1 CRYBG3 ASCC3 CEP57 GCN1 KIF11 TANGO6 PCNT SYMPK

7.02e-0594113718int:KDM1A
InteractionTP53BP1 interactions

CDK8 OGT CTC1 CDK19 HUWE1 THOC2 PALB2 MED15 CCNT1 PARP1 CHEK2 HERC2 PCNT

7.21e-0553313713int:TP53BP1
InteractionMED1 interactions

CDK8 CDK19 MED15 CCNT1 PARP1 AKAP9 CHEK2 HERC2

8.43e-052061378int:MED1
InteractionMED26 interactions

CDK8 CDK19 MED15 CCNT1 CCNT2 TAF1

9.10e-051071376int:MED26
InteractionS100A2 interactions

KIF23 MATN2 PALB2 SPC24 RESF1 CEP295 CRYBG3 CEP57 DHX34 PCNT SYMPK

1.21e-0441213711int:S100A2
InteractionPHF21A interactions

OGT UBR4 HUWE1 RESF1 XRN1 TAF1 CRYBG3 ASCC3 TANGO6 PCNT

1.21e-0434313710int:PHF21A
InteractionPP2D1 interactions

PP2D1 CSK

1.37e-0431372int:PP2D1
InteractionAKAP9 interactions

HUWE1 RFC5 THOC2 CEP55 AKAP9 HERC2 CEP57 PCNT

1.37e-042211378int:AKAP9
InteractionIMPDH2 interactions

KIF23 OGT UBR4 HUWE1 DDX3X PARP1 AKAP9 CLK1 CRYBG3 ASCC3 DYNC1H1

1.43e-0442013711int:IMPDH2
InteractionRCOR1 interactions

OGT UBR4 HUWE1 PALB2 ACTR1A RESF1 XRN1 CBX1 TAF1 ASCC3 GCN1 TANGO6

1.43e-0449413712int:RCOR1
InteractionSLX4 interactions

PDS5B KIF23 OGT WRN PEPD DDX3X CCNT1 PARP1 RESF1 ASCC3 GCN1 DYNC1H1 SYMPK

1.46e-0457213713int:SLX4
InteractionCCND1 interactions

CDK8 OGT RFC5 FBXO43 TAF1 CEP57 GCN1 DYNC1H1 SYMPK

1.51e-042861379int:CCND1
GeneFamilyCDC like kinases

CLK1 CLK2 CLK3

4.75e-074903480
GeneFamilyCyclins|P-TEFb complex

CCNT1 CCNT2

1.46e-0449021281
GeneFamilyCyclins|Mediator complex

CDK8 CDK19 MED15

5.84e-04339031061
GeneFamilyATP binding cassette subfamily A

ABCA13 ABCA6

2.14e-0314902805
GeneFamilyAT-rich interaction domain containing

KDM5C KDM5D

2.47e-0315902418
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

CDK8 PDS5B KIF23 OGT CDK19 WRN PSD3 SPG11 THOC2 WDR37 ORC5 AKAP9 RIN2 CRYBG3 ASCC3 KIF11 PCNT

2.78e-0685613817M4500
CoexpressionGSE8835_CD4_VS_CD8_TCELL_UP

NBEAL1 HUWE1 PALB2 ACTR1B TAF1 TCTN2 PCNT SMG6

1.14e-052001388M6254
CoexpressionHALLMARK_G2M_CHECKPOINT

PDS5B KIF23 WRN CCNT1 ORC5 CBX1 PLK4 KIF11

1.14e-052001388M5901
CoexpressionGSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_UP

KIF23 CTC1 MATN2 WDR37 PALB2 CEP55 SPC24 ADAMTS18

1.14e-052001388M7869
CoexpressionAFFAR_YY1_TARGETS_DN

KIF23 PDGFRA MATN2 CHRDL1 MMP13 PLK4 NR1H4 KIF11

7.36e-052601388M1471
CoexpressionFUJII_YBX1_TARGETS_DN

CDK8 PDE3B KIF23 RFC5 CBX1 PLK4 KIF11

7.81e-051941387M14340
CoexpressionGSE23321_CD8_STEM_CELL_MEMORY_VS_NAIVE_CD8_TCELL_DN

PDE3B SPG11 CSK XRN1 DNASE1L1 KIF11 PCNT

8.33e-051961387M8441
CoexpressionGSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_UP

CTNNAL1 CDK19 HUWE1 FAM171B ARNT AKAP9 TAF1

8.60e-051971387M8022
CoexpressionGSE30083_SP3_VS_SP4_THYMOCYTE_UP

KIF23 CTC1 ACSM1 PSD3 IPO9 CLK3 CBX1

9.45e-052001387M5036
CoexpressionGSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_UP

OGT CDK19 WDR37 AKAP9 CSK DIAPH2 IL2RG

9.45e-052001387M7648
CoexpressionGSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN

KIF23 OGT RFC5 CEP55 SPC24 PLK4 XPO7

9.45e-052001387M8485
CoexpressionGSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN

PSD3 MADD SAMD9L AKAP9 CHEK2 HSH2D ZNF841

9.45e-052001387M7495
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HUWE1 KDM5D MADD AKAP9 CLK1 SPHKAP XRN1 ASCC3 DYNC1H1 UNC80

6.09e-10195139107796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

PDE3B NBEAL1 ADGRV1 HUWE1 THOC2 AKAP9 CRYBG3 CPLANE1 DYNC1H1

1.03e-081931399abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HUWE1 KDM5D MADD AKAP9 CLK1 SPHKAP ASCC3 DYNC1H1 UNC80

1.13e-0819513993e519cffa6144a62b06124642a14c9ff39b76554
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DDX3X SAMD9L RESF1 AKAP9 CLK1 XRN1 HSH2D DYNC1H1

2.27e-07200139812f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells-Neuroepithelial_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

KIF23 PDGFRA CEP55 SPC24 CHEK2 FBXO43 PLK4 KIF11

2.27e-072001398203b9a5de4430713da01b3331e69381db449a3a0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells|GW26 / Sample Type, Dataset, Time_group, and Cell type.

KIF23 PDGFRA CEP55 SPC24 CHEK2 FBXO43 PLK4 KIF11

2.27e-072001398a854e19703dc920e48304541e2b06ed013292f3e
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCTD19 MYO7B ADGRV1 PIK3C2G SPHKAP TDRD6 UNC80

7.26e-071601397c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCTD19 MYO7B ADGRV1 PIK3C2G SPHKAP TDRD6 UNC80

7.26e-07160139725c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellC_02|World / shred on cell type and cluster

ANPEP MATN2 PEPD CUBN PIK3C2G G6PC1 NR1H4

8.92e-071651397a456c2c9ffe8dc91e17cac84ba87b88e016f8e6d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF23 KCTD19 CEP55 SPC24 FBXO43 PLK4 KIF11

1.01e-061681397d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF23 KCTD19 CEP55 SPC24 FBXO43 CEP295 KIF11

1.05e-061691397b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell10x5'-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T|Lung / Manually curated celltypes from each tissue

CTNNAL1 RFC5 CEP55 SPC24 FBXO43 PLK4 KIF11

1.13e-061711397976361f67dd725870e0513ae7a92f2dcaee17148
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF23 KCTD19 CEP55 SPC24 FBXO43 PLK4 KIF11

1.27e-061741397dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

B3GALT1 KIF23 PDGFRA ADGRV1 CEP295 PLK4 KIF11

1.27e-0617413977b2f35add804981c7d588a996bdbca6ec11a1ca5
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 CEP55 SPC24 CRYBG3 KIF11 TANGO6 SYMPK

1.27e-0617413976c36d607c48267a75ab4da6fb2fe3f931d1b3b52
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF23 KCTD19 CEP55 SPC24 FBXO43 PLK4 KIF11

1.32e-061751397876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 RFC5 PALB2 SPC24 FER1L4 PLK4 KIF11

1.43e-0617713974197cf2b1e743230c821f422836fa5991b155a52
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NBEAL1 SAMD9L AKAP9 XRN1 DIAPH2 CBX1 ASCC3

1.48e-06178139701dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 MYO7B ABCA13 ADGRV1 PIK3C2G PCDH11X UNC80

1.85e-0618413972cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 MYO7B ABCA13 ADGRV1 PIK3C2G PCDH11X UNC80

1.85e-061841397ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 MYO7B ABCA13 ADGRV1 PIK3C2G PCDH11X UNC80

1.85e-0618413972b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA13 RFC5 CEP55 SPC24 PLK4 ATP4A KIF11

1.92e-06185139747c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

ANPEP MYO7B MYOM3 CUBN G6PC1 CDH9 NR1H4

2.06e-061871397738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B CEP55 SPC24 PIK3C2G FBXO43 PLK4 KIF11

2.06e-061871397057569c9437219ecc396aa6e673b1178a2273837
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-T_NK_proliferative|Multiple_Sclerosis / Disease, Lineage and Cell Type

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

2.13e-0618813976c05797a5d0635d89ffcf4aca52178687129ccb4
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PDS5B KIF23 RFC5 SPC24 IPO9 CEP295 KIF11

2.29e-061901397d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIF23 CEP55 SPC24 CHEK2 FBXO43 PLK4 KIF11

2.37e-0619113970ba5b112a82e489f5a21966f78a403a7436ce73b
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KIF23 PDGFRA RFC5 CEP55 SPC24 PLK4 KIF11

2.37e-061911397b978afe76754cc56e1672abca27be289bb56375b
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KIF23 CEP55 SPC24 CHEK2 FBXO43 PLK4 KIF11

2.45e-0619213970a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIF23 CEP55 SPC24 CHEK2 FBXO43 PLK4 KIF11

2.45e-061921397026f3e38970bea1e6e8d76a4e2becdfb8484b2ff
ToppCellProliferating|World / shred by cell class for mouse tongue

KIF23 RFC5 CEP55 SPC24 CHEK2 PLK4 KIF11

2.45e-061921397f081f3f957cc782294e118fcc1055f6a4264ee98
ToppCellcontrol-Myeloid-Immature_Neutrophils_2|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIF23 ABCA13 PIWIL4 CEP55 SPC24 PLK4 KIF11

2.54e-06193139733349830e9eba506470ad3661fad5e5a283d20ca
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.62e-061941397f39a471293ecc5c5967b00e772b8f48ebc9affbe
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KIF23 CEP55 SPC24 CHEK2 FBXO43 PLK4 KIF11

2.62e-061941397f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell3'_v3-blood-Lymphocytic_NK-Cycling_NK|blood / Manually curated celltypes from each tissue

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

2.62e-061941397bf9734abaad603ade2a6a6940918aaf1e1c4e2cd
ToppCellControl-Lymphoid_T/NK-T/NK_proliferative|Control / Disease group, lineage and cell class

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.62e-0619413979bbb124001fba7450f4639f47f9b720a483e7242
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.62e-061941397a75ecd0b0a928d4646602f7d16a645f6b3df3af5
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.62e-06194139717744fd6645cf5a447a01a83f07e8d305c2bcd9c
ToppCellcontrol-Lymphocytic-Prol._cells|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIF23 RFC5 CEP55 SPC24 FBXO43 PLK4 KIF11

2.62e-0619413974c76508de3291c952386caffda2d559629ba5998
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.62e-061941397e14f66f7584909621b776292fbd52808273fd2ee
ToppCellHealthy/Control-T/NK_proliferative|Healthy/Control / Disease group and Cell class

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.72e-061951397957458fdc39723f4a31bd7fd3ce32891aa3fd462
ToppCellcontrol-Myeloid-Immature_Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIF23 ABCA13 PIWIL4 CEP55 SPC24 PLK4 KIF11

2.72e-061951397bfaceb0601cf3855f38d6e1f482f01ad03ef11fe
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF23 CEP55 SPC24 FBXO43 IL2RG PLK4 KIF11

2.81e-0619613979d4f0a95e49bda25864cbe27e4e86096cba5609f
ToppCellControl-T/NK_proliferative|Control / Disease condition and Cell class

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.81e-0619613977b7bc25aef49bfd64f79303a92d527bf8188f7a6
ToppCellsevere_COVID-19-T/NK_proliferative|World / disease group, cell group and cell class (v2)

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

2.90e-061971397189d97a6c2ff8803db8cc05e205c9d88dac3911f
ToppCellMild_COVID-19-T/NK-proliferating_T/NK|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.90e-0619713975fd52fba2cb6fa67377f873da2ff6ce9c83b0591
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KIF23 CEP55 SPC24 CHEK2 FBXO43 PLK4 KIF11

2.90e-06197139784ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellHealthy/Control-T/NK_proliferative|World / Disease group and Cell class

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.90e-0619713974a4d3083938783d6f5b87da02f10e501917da0b4
ToppCellCOVID-19_Severe-T/NK_proliferative|COVID-19_Severe / Disease condition and Cell class

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

2.90e-061971397718a84e9a8248080f2d964e7c6a3ba183ece9592
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.90e-061971397d7a9296092153cf66426911fecd810f0c1ef978e
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.90e-061971397dcff23240bb7cb652d7426b29355aa74442ef6fc
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.90e-061971397434a5686a103bb766e0d80038413f0e12ea3981a
ToppCellMild-Lymphoid-T-Proliferating_T|Mild / Condition, Lineage, Cell class and cell subclass

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.90e-061971397794517c70089da109f4c6489fe406c0ba6882b76
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.90e-0619713976bddfa199ca812d9e518eaa02c3d4fb67e9f5b16
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.90e-061971397c0a71a9452febda433bc544e4ac0a79c43dcf13e
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.90e-061971397f34b1e34f1f0694564031077172c890b233ce8b7
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 RFC5 CEP55 SPC24 CBX1 PLK4 KIF11

2.90e-0619713979b2c67de46bd59bf56c81a0d10b84cf4a041c120
ToppCellmild-Myeloid-Immature_Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIF23 ABCA13 PIWIL4 CEP55 SPC24 PLK4 KIF11

2.90e-061971397bd9d57e0c873f6526dca322f4dad8e6bd692586c
ToppCellHealthy_donor-T/NK_proliferative|Healthy_donor / disease group, cell group and cell class (v2)

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

2.90e-061971397b6bbf87e5823fa66b4cad6a7be4f777356887b59
ToppCellCOVID-19_Moderate-T/NK_proliferative|COVID-19_Moderate / disease group, cell group and cell class

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

3.00e-061981397166c000fb0e19602ffdd8bf2b2f19be2c6df96a6
ToppCellCOVID-19_Moderate-T/NK_proliferative|World / disease group, cell group and cell class

KIF23 RFC5 CEP55 SPC24 FBXO43 PLK4 KIF11

3.00e-061981397bf0131fbca6032e1aab4aa807f8c1d3be689cb7f
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

3.10e-06199139711c3d9fe811a4619347f47d2b0e94066e3085625
ToppCellmild_COVID-19-T/NK_proliferative|World / disease group, cell group and cell class (v2)

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

3.10e-061991397d44cc74d7171d96add61dae821daf774b17d4c69
ToppCellVE-cycling|VE / Condition, Cell_class and T cell subcluster

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

3.10e-06199139747c47ebc318a0b98841ca2656837bbd068899559
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

3.10e-06199139736c80907b2ec1cbcd1b4e841e6c02a4792591d74
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

3.10e-061991397bf4c31902ae8358215245a2e11b5a2fe4ca1bc8c
ToppCellCOVID-19_Mild-Lymphoid_T/NK-T/NK_proliferative|COVID-19_Mild / Disease group, lineage and cell class

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

3.10e-061991397ddea0e5c1cb6a096ab8e09a8c3c37c1bff381d9c
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

3.10e-0619913977beb0e07a27fea94674f24eb61c381b0de38ed3e
ToppCellCOVID-19_Mild-T/NK_proliferative|COVID-19_Mild / Disease condition and Cell class

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

3.10e-0619913979f9a88d2b099646c1e1a7ee3f8d39cb1a2498ad7
ToppCellVE-cycling-|VE / Condition, Cell_class and T cell subcluster

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

3.10e-061991397c0a67149a19b65b3069dbc5261d81f658e6e39a2
ToppCellmild_COVID-19-T/NK_proliferative|mild_COVID-19 / disease group, cell group and cell class (v2)

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

3.10e-061991397df2fcaf01b1b48632f84e7355ef21d20853f0664
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-T/NK_proliferative|COVID-19_Mild / Disease, condition lineage and cell class

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

3.21e-0620013976126a3bbafe2110fba0c1c4493035df4e8193d22
ToppCellmLN-T_cell-cycling_gd_T|mLN / Region, Cell class and subclass

KIF23 CEP55 SPC24 CHEK2 ADAMTS18 PLK4 KIF11

3.21e-0620013974efeef51f885ee8f6dd3911a536cc49e3c14da98
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte|healthy_donor / Disease condition, Lineage, Cell class and subclass

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

3.21e-062001397e4eb915c29909cf8535a3603c68976545c05e54b
ToppCellmLN-(1)_T_cell-(18)_cycling_gd_T|mLN / shred on region, Cell_type, and subtype

KIF23 CEP55 SPC24 CHEK2 ADAMTS18 PLK4 KIF11

3.21e-062001397e8a0a88a8344e80783931115bbe6cd5b62a4c1f7
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte-|healthy_donor / Disease condition, Lineage, Cell class and subclass

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

3.21e-062001397415e7556b5ac45688e2c6c30a52bd40e0eb27c7d
ToppCellMS-Multiple_Sclerosis-Lymphocyte-T/NK-T/NK_proliferative|Multiple_Sclerosis / Disease, condition lineage and cell class

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

3.21e-0620013977faf1e37364203a08d2b2544979e848b41e36b1c
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

KIF23 CTNNAL1 CEP55 SPC24 CHEK2 PLK4 KIF11

3.21e-062001397cea58274efbe7f9e3c3ef9fbb768ebfb917e21d9
ToppCell356C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KIF23 CTNNAL1 RFC5 CEP55 SPC24 PLK4 KIF11

3.21e-0620013975d11a2c0021805e78d97dc1638bf73ca1faede66
ToppCellMS-IIF-Lymphocyte-T/NK-T/NK_proliferative|IIF / Disease, condition lineage and cell class

KIF23 CTNNAL1 CEP55 SPC24 FBXO43 PLK4 KIF11

3.21e-062001397c7c1806a1054b2b034a26a18aac93fc3bec4dbc8
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIF23 RFC5 CEP55 CHEK2 FBXO43 PLK4 KIF11

3.21e-062001397af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCellNeuronal-Excitatory-eE(FEZF2_SLC17A7)-eE_2|Neuronal / cells hierarchy compared to all cells using T-Statistic

FAT4 PLCXD2 PIWIL4 SAMD9L PIK3C2G SPHKAP PCDH11X

3.21e-062001397d31e26387d879ee30731c497cea6aaf4746e40d9
ToppCellmild-T/NK_proliferative|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KIF23 CTNNAL1 RFC5 CEP55 PLK4 KIF11 PCNT

3.21e-06200139763cc57b9331459efbb73051d174d198a3568b938
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 RFC5 WDR37 SPC24 BTK KIF11

6.63e-06146139645d7cb73776e60d22f335a651845e21e16948fcc
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-6|TCGA-Kidney / Sample_Type by Project: Shred V9

KIF23 CEP55 SPC24 FBXO43 PLK4 KIF11

9.69e-061561396d249747c7108a0edfc72d24c09b0b0e4ed662b40
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF23 CEP55 SPC24 FBXO43 PLK4 KIF11

1.33e-051651396eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KCTD19 CEP55 SPC24 FBXO43 PLK4 KIF11

1.43e-05167139650c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 CEP55 SPC24 IL2RG PLK4 KIF11

1.58e-0517013966b91d4cbe0697b65bfb2e099e7a9b39ea2fba3a9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANPEP MYOM3 PEPD CUBN G6PC1 CDH9

1.63e-051711396f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCelldroplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RFC5 CEP55 SPC24 TSSK4 PLK4 KIF11

1.74e-051731396c399786aa25bdbe3394988db6955842b5b7e6b41
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RFC5 CEP55 SPC24 TSSK4 PLK4 KIF11

1.74e-05173139631784679190fbd95fc23d7c66008eb21b8c7cc5d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KCTD19 CEP55 SPC24 FBXO43 PLK4 KIF11

1.80e-05174139684da9faff088d05233183b425385beb054c92d1b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 PLCXD2 PIWIL4 PIK3C2G SPHKAP PCDH11X

1.80e-051741396912a9e892b29d945666fc37c986009c97c668ac8
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE3B PDGFRA PSD3 ABCA6 PCDH11X CRYBG3

1.80e-051741396f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 PIWIL4 LRRC3B PIK3C2G CRYBG3 CDH9

1.80e-0517413967d4b860e05b5931f6f9d757a68f75ff35597a47a
ToppCellfacs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 CEP55 SPC24 CHEK2 PLK4 KIF11

1.98e-0517713968a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCellfacs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 CEP55 SPC24 CHEK2 PLK4 KIF11

1.98e-051771396e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCell10x5'-blood-Lymphocytic_NK-Cycling_NK|blood / Manually curated celltypes from each tissue

KIF23 CEP55 SPC24 TSSK4 PLK4 KIF11

2.11e-051791396c93711273055a999335ba8d0f6500e4549f46cec
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANPEP MYO7B MYOM3 CUBN G6PC1 CDH9

2.11e-051791396d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac|lymph-node_spleen / Manually curated celltypes from each tissue

KIF23 PDGFRA CEP55 SPC24 KIF11 TRIM60

2.18e-0518013964eea8366cdb82c356325ce88f09ad8b302c17a07
Drugtandutinib

PDGFRA CLK1 CLK2 CLK3

1.67e-06151384CID003038522
DrugCarcinine [56897-53-1]; Up 200; 22uM; MCF7; HT_HG-U133A

CCNT2 RIN2 LPIN2 PLCD1 TAF1 CPLANE1 IL2RG TCTN2 SYMPK

3.32e-0619713893242_UP
Diseasedevelopmental and epileptic encephalopathy 87 (implicated_via_orthology)

CDK8 CDK19

2.02e-0521332DOID:0112221 (implicated_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of breast

PALB2 BTK CHEK2 HERC2

3.51e-05411334C0496956
DiseaseBreast adenocarcinoma

PALB2 BTK CHEK2 HERC2

3.51e-05411334C0858252
DiseaseColorectal Carcinoma

ABCA13 WRN CUBN PARP1 ARNT AKAP9 ABCA6 LRRC3B GUCY2C CHEK2 PCDH11X ADAMTS18

8.35e-0570213312C0009402
Diseasetelomere length

CTC1 PSD3 PARP1 PIK3C2G CEP295 CPLANE1 CDH9 UNC80

9.12e-053131338EFO_0004505
Diseasesyndromic X-linked intellectual disability (is_implicated_in)

DDX3X TAF1

1.20e-0441332DOID:0060309 (is_implicated_in)
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5C KDM5D

1.20e-0441332DOID:0060809 (implicated_via_orthology)
Diseaseheel bone mineral density, urate measurement

PDGFRA VWA8 PLCXD2 WRN PSD3 SERPINI2

1.82e-041821336EFO_0004531, EFO_0009270
DiseaseArterial Fatty Streak

PARP1 NR1H4

2.00e-0451332C0015697
DiseaseAtheroma

PARP1 NR1H4

2.00e-0451332C0264956
DiseasePlaque, Atherosclerotic

PARP1 NR1H4

2.00e-0451332C2936350
DiseaseFibroatheroma

PARP1 NR1H4

2.00e-0451332C2936351
DiseaseIntellectual Disability

CDK8 KDM5C WDR37 DDX3X PARP1 POLR3B TAF1 ASCC3 DYNC1H1

2.02e-044471339C3714756
Diseasebreast carcinoma

PDS5B PALB2 MADD CEP55 KCNU1 AKAP9 CLK1 AOPEP LPA RIN2 CHEK2 LRRD1 PCNT SMG6

2.12e-04101913314EFO_0000305
Diseaseangina pectoris

NBEAL1 SPC24 IPO9 LPA SMG6

2.62e-041251335EFO_0003913
DiseaseColorectal Neoplasms

ABCA13 PARP1 ARNT ABCA6 LRRC3B GUCY2C CHEK2

2.71e-042771337C0009404
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

PSD3 SPG11 CEP55 ABCA6 LPA

2.82e-041271335EFO_0008595, EFO_0020947
DiseaseCorneal astigmatism

PDGFRA MADD KCNU1 HERC2

4.14e-04771334EFO_1002040
DiseaseProfound Mental Retardation

KDM5C PARP1 POLR3B ASCC3 DYNC1H1

4.28e-041391335C0020796
DiseaseMental Retardation, Psychosocial

KDM5C PARP1 POLR3B ASCC3 DYNC1H1

4.28e-041391335C0025363
DiseaseMental deficiency

KDM5C PARP1 POLR3B ASCC3 DYNC1H1

4.28e-041391335C0917816
Diseasephospholipids:total lipids ratio, high density lipoprotein cholesterol measurement

PEPD PSD3 MADD CEP55 ABCA6 LPA ATP4A

5.02e-043071337EFO_0004612, EFO_0020946
DiseaseAUTISM, SUSCEPTIBILITY TO, 15

CDK8 WDR37

5.55e-0481332C2677504
Diseasefemale breast cancer (is_implicated_in)

PALB2 CHEK2

5.55e-0481332DOID:0050671 (is_implicated_in)
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

PSD3 SPG11 CEP55 ABCA6 LPA

6.05e-041501335EFO_0004611, EFO_0020947
Diseasenevus count, cutaneous melanoma

ADGRV1 PARP1 ARNT HERC2

7.79e-04911334EFO_0000389, EFO_0004632
Diseasesquamous cell carcinoma, esophageal carcinoma

CHEK2 SMG6

8.86e-04101332EFO_0000707, EFO_0002916
Diseasemelanoma

FAT4 PDGFRA UBR4 CUBN PARP1 ARNT

9.35e-042481336C0025202
Diseasefree cholesterol to total lipids in very small VLDL percentage

PSD3 ABCA6 LPA

9.68e-04431333EFO_0022290
Diseasegrey matter volume measurement

PSD3 CUBN ASCC3

1.04e-03441333EFO_0005420
DiseaseC-reactive protein measurement

PSD3 SPG11 CCDC168 THOC2 MADD IPO9 ABCA6 AOPEP LPA SPHKAP CCDC171 GCN1 G6PC1 NR1H4

1.12e-03120613314EFO_0004458
DiseaseMalignant neoplasm of breast

ABHD12B UBR4 CUBN PALB2 DDX3X PARP1 AKAP9 LRRC3B BTK CHEK2 SLC39A6 HERC2 G6PC1

1.16e-03107413313C0006142
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

OGT MADD PARP1 G6PC1

1.33e-031051334DOID:9352 (implicated_via_orthology)
Diseaseserum albumin measurement

PEPD PSD3 ADGRV1 MADD ARNT ABCA6 CSK LPA PCNT

1.49e-035921339EFO_0004535
DiseaseCiliopathies

ADGRV1 CPLANE1 NR1H4 TCTN2

1.57e-031101334C4277690
Diseasecoronary artery disease, factor VII measurement

NBEAL1 PNLDC1 LPA SMG6

1.63e-031111334EFO_0001645, EFO_0004619
Diseaseapolipoprotein A 1 measurement

PDE3B PEPD PSD3 SPG11 MADD SPC24 ABCA6 LPA LPIN2 TANGO6 SMG6

1.63e-0384813311EFO_0004614
Diseaselipoprotein A measurement

PNLDC1 ABCA6 LPA CDH9

1.68e-031121334EFO_0006925
Diseaseglucose measurement

PDE3B VWA8 PSD3 MADD CSK PIK3C2G KIF11

1.73e-033801337EFO_0004468
Diseasetrimethylamine-N-oxide measurement

CUBN TTC13

1.77e-03141332EFO_0010541
Diseaseurinary bladder cancer (biomarker_via_orthology)

CHEK2 VHLL

1.77e-03141332DOID:11054 (biomarker_via_orthology)
DiseaseHereditary Breast and Ovarian Cancer Syndrome

PALB2 CHEK2

1.77e-03141332C0677776
DiseaseMetastatic melanoma

PDGFRA GUCY2C TAF1

1.88e-03541333C0278883
Diseasealcohol use disorder (implicated_via_orthology)

KDM5C PSD3 KDM5D MADD KCNU1

1.94e-031951335DOID:1574 (implicated_via_orthology)
Diseaseomega-6 polyunsaturated fatty acid measurement

PSD3 C1orf141 ABCA6 FER1L4 LPA

2.03e-031971335EFO_0005680
Diseasevon Willebrand factor measurement, coronary artery disease

NBEAL1 PNLDC1 LPA SMG6

2.04e-031181334EFO_0001645, EFO_0004629
DiseaseMeckel-Gruber syndrome

CEP55 TCTN2

2.04e-03151332C0265215
DiseaseProteinuria

CUBN SMG6

2.04e-03151332HP_0000093
Diseaseresponse to platinum based chemotherapy, magnesium measurement

NTMT2 PSD3

2.04e-03151332EFO_0004647, EFO_0004845
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5C KDM5D

2.32e-03161332DOID:0050888 (implicated_via_orthology)
DiseaseAtherosclerosis

PARP1 LPA NR1H4

2.42e-03591333C0004153
Diseasecolon cancer (is_marker_for)

KDM5C ACTR1A PLK4

2.42e-03591333DOID:219 (is_marker_for)
Diseasetriglycerides to total lipids in small LDL percentage

PSD3 ABCA6 LPA

2.42e-03591333EFO_0022337
DiseaseAtherogenesis

PARP1 LPA NR1H4

2.42e-03591333C1563937
Diseasecholesteryl esters to total lipids in large HDL percentage

PSD3 MADD LPA

2.42e-03591333EFO_0022248
Diseaselobe attachment

FAT4 PDGFRA PLCXD2 CEP55 ADAMTS18

2.52e-032071335EFO_0007667
Diseasebone mineral content measurement

PEPD ADGRV1 GUCY2C HERC2

2.89e-031301334EFO_0007621
Diseasecoronary artery disease, plasminogen activator inhibitor 1 measurement

NBEAL1 LPA SMG6

2.92e-03631333EFO_0001645, EFO_0004792
Diseasecoronary artery disease

CDK8 PDS5B FAT4 NBEAL1 PSD3 VWDE SPC24 PARP1 LPA CHRDL1 MMP13 DNASE1L1 SMG6

2.94e-03119413313EFO_0001645
DiseaseGlobal developmental delay

CDK8 KDM5C WDR37 TAF1

3.14e-031331334C0557874
DiseaseHereditary Non-Polyposis Colon Cancer Type 2

PALB2 CHEK2

3.28e-03191332C1333991
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

PALB2 CHEK2

3.28e-03191332C2936783
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

PSD3 SPG11 CEP55 ABCA6 LPA

3.40e-032221335EFO_0008317, EFO_0020943
Diseasesquamous cell carcinoma

ERBIN CHEK2 HERC2

3.47e-03671333EFO_0000707
Diseaseglycine measurement

ANPEP VWA8 ADGRV1 UNC80

3.49e-031371334EFO_0009767
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

PSD3 SPG11 CEP55 ABCA6 LPA

3.60e-032251335EFO_0008317, EFO_0020947
DiseaseFamilial aplasia of the vermis

CPLANE1 TCTN2

3.63e-03201332cv:C0431399
DiseaseAdenocarcinoma of prostate

PALB2 CHEK2

3.63e-03201332C0007112
Diseasetriglycerides to total lipids in very small VLDL percentage

PSD3 ABCA6 LPA

3.78e-03691333EFO_0022341
Diseasetriglyceride measurement, body fat percentage

PEPD KCNU1

4.00e-03211332EFO_0004530, EFO_0007800
DiseaseJoubert syndrome 1

CPLANE1 TCTN2

4.00e-03211332C4551568
Diseasetissue plasminogen activator measurement, coronary artery disease

NBEAL1 LPA SMG6

4.09e-03711333EFO_0001645, EFO_0004791
Diseasesevere acute respiratory syndrome, COVID-19

WRN PSD3 MED15 PIK3C2G PCDH11X DIAPH2 CEP57

4.24e-034471337EFO_0000694, MONDO_0100096
DiseaseSeckel syndrome

PLK4 PCNT

4.39e-03221332C0265202
Diseaseseminoma (is_marker_for)

PDGFRA CHEK2

4.39e-03221332DOID:4440 (is_marker_for)
DiseaseHepatitis

PDS5B FAT4

4.39e-03221332HP_0012115
DiseaseDown syndrome (is_marker_for)

ACTR1A PCNT

4.39e-03221332DOID:14250 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
PSFLTDQELKHLILE

ARNT

156

P27540
ALKTQTPQLHFLDTD

SMG6

466

Q86US8
NITVLFLHSNKLETL

ERBIN

346

Q96RT1
NLPKEETEFLSIHSQ

AKAP9

1296

Q99996
LTHEFLQILEKTPNR

CCNT2

236

O60583
EELFHPLTSLQTLKL

CPN2

186

P22792
LLTKNRFSSHPLENE

C1orf141

221

Q5JVX7
PNVIALQKVFLSHSD

CDK19

76

Q9BWU1
SFVSVQDLKTHQRLP

CTC1

66

Q2NKJ3
LKFELNRSHISETPL

CRYBG3

611

Q68DQ2
LAEKHLFSTIPELIN

BTK

346

Q06187
LTHTDLKPENILFVN

CLK2

286

P49760
NDFTLQLPKLHLETF

CCDC171

1171

Q6TFL3
VLLESKSSPFNLLHE

GZF1

6

Q9H116
HFEVQSSKVPNLSLI

FAT4

406

Q6V0I7
TLVHTEILKLFPQAA

ABCA6

1521

Q8N139
NIPFLVILISTTHKE

B3GALT1

76

Q9Y5Z6
DENVKFLSSPLLILH

ABHD12B

286

Q7Z5M8
KDQLQTFSEEHPVLL

ACTR1B

96

P42025
NTTLFVHLLDDNIPE

ADGRV1

2766

Q8WXG9
SLKQLHEFAITEPLV

CEP55

396

Q53EZ4
FDHQQLAKLIQESPT

CEP57

376

Q86XR8
QLTHTDLKPENILFV

CLK3

426

P49761
FSLSHDLQNSPKIII

ABCA13

1606

Q86UQ4
PSFLQLREQLEHIKT

CSK

431

P41240
LSLDHSKLVDVPFQV

APBB1

516

O00213
AEFNITLIHPKDLTA

ANPEP

231

P15144
EHLLEQKTLSPRTLQ

AOPEP

716

Q8N6M6
ELTHEFLQILEKTPN

CCNT1

236

O60563
PFSEHRTQVSLKDQI

CHEK2

426

O96017
LTFEEHINNIKPSII

DIAPH2

801

O60879
QELHLELKPSAILSS

ADAMTS18

106

Q8TE60
ELKPSAILSSHFIVQ

ADAMTS18

111

Q8TE60
HTDLKPENILFVQSD

CLK1

286

P49759
KIDTSTLNLFQHLPE

NBEAL1

2296

Q6ZS30
ETQFAQIFEPLHKSL

PDS5B

741

Q9NTI5
ISKFEVNNTILHPEI

PEPD

166

P12955
IFPLETNETNHVSLK

GUCY2C

476

P25092
HSQLQKQFASLTLPE

PIK3C2G

1246

O75747
TKSLQELFLAHILSP

PARP1

466

P09874
TLHISPKQFVVDLLA

KCTD19

856

Q17RG1
KTELTPDQQTLLHFI

NR1H4

256

Q96RI1
EIKPTFSQLEAVNLH

PDGFRA

316

P16234
DISNVKHVINFDLPS

DDX3X

506

O00571
EIPVDISFSKQLLHL

LRRD1

501

A4D1F6
ELQEIASEPTNKHLF

MATN2

801

O00339
SLNTQPILNLEKFHE

MADD

436

Q8WXG6
STPTLLESIQHVFIK

HERC2

4026

O95714
IPRTLHQIFEKLTDN

KIF11

136

P52732
DLLLEITAFHSQTLP

FER1L4

86

A9Z1Z3
LFDSQPDLLHQLVTL

KDM5D

546

Q9BY66
GSQVHLPKLEFTLSQ

LENG9

456

Q96B70
LHPQQVDAELFLTKS

MMP13

311

P45452
SPQLAKLQESFITHI

PDE3B

981

Q13370
LKNTPQVSLHRFETI

FAM205A

341

Q6ZU69
LQLPDKHSVTALLNT

MED15

761

Q96RN5
SIHIKVDPLFTELLN

GCN1

2376

Q92616
ILTELKNPSNIHFIE

KCNU1

861

A8MYU2
ITSIPNEIFKDLHQL

LRRC3B

76

Q96PB8
HSPKNLLLNFVTIEE

PCDH11X

876

Q9BZA7
VLDTLIQLAKVFPSH

HUWE1

3336

Q7Z6Z7
QPFHQEEKESLSLQL

PCNT

1081

O95613
SLDALVTFHQQKPIE

HSH2D

101

Q96JZ2
DQHPSATLFVKISLQ

PLCD1

741

P51178
HDLKNIRFTSPVSLE

PALB2

276

Q86YC2
NLSKTPALQLVHELF

FBXO43

436

Q4G163
KHLEISFDNNFLIPS

CUBN

2841

O60494
ELKLSQAHSVQPLSL

DNASE1L1

271

P49184
PLKTSQDLIHQLEVF

CTNNAL1

616

Q9UBT7
IKTEQSFRLIPLQHS

CPLANE1

971

Q9H799
ELPHFKLVTRTTLSQ

CHRDL1

401

Q9BU40
PTFQELQRVLHKLTT

ANKZF1

331

Q9H8Y5
VHIDTTPFASLLKNL

G6PC1

251

P35575
SIIDVNLPKFLSHDL

DNAH7

1531

Q8WXX0
PDLIAEFLQSQKTAH

CBX1

61

P83916
KDQLQTFSEEHPVLL

ACTR1A

96

P61163
LLFLKSAAPEQSHVV

LPA

11

P08519
LQVFPSHSALKLEDI

MS4A14

301

Q96JA4
APENLTLHKLSESQL

IL2RG

156

P31785
DQLKVSESTHVLQPF

IPO9

546

Q96P70
DIKHLLPVETQRFQS

DYNC1H1

1556

Q14204
IFEAEQLSLPHTLNI

CCDC168

4521

Q8NDH2
VFTLNHPLTIASVDK

FAM217A

121

Q8IXS0
PNVISLQKVFLSHAD

CDK8

76

P49336
SKIFSSHLQIPQLQD

CEP295

1321

Q9C0D2
HQLLSFVSLLETNKP

DHX34

876

Q14147
FHTVDTILLQEKPNS

CDH9

16

Q9ULB4
TNKFQLSIHTLEDPR

ATP4A

496

P20648
QLLFLHQDILTSPVS

C18orf63

46

Q68DL7
ILQTSDLFSTPEQLH

FAM171B

541

Q6P995
HFSTLAIKQNPLLAE

OGT

76

O15294
SHSVFNIKLVQAPLD

KIF23

301

Q02241
SKHVLLPVFNSVELV

NTMT2

131

Q5VVY1
DDLLLPAQSTLQTKH

SPHKAP

906

Q2M3C7
AIITFHPQKLSQEEL

TRMT2B

241

Q96GJ1
FNTLLPHANETKEIL

TDRD6

1816

O60522
LSTIQKFINEDRLPH

RFC5

41

P40937
FIPHTSLQVKNSQLL

RESF1

236

Q9HCM1
NLIDPIHEFKALTNT

SAMD9L

191

Q8IVG5
QHDATKLLPSVTELF

TAF1L

236

Q8IZX4
QHDATKLLPSVTELF

TAF1

216

P21675
VTQTLLKTLELPHVF

ORC5

46

O43913
QNIHSLFPVLIDTKS

PNLDC1

281

Q8NA58
FLVAQSIHKEPSLEL

PIWIL4

831

Q7Z3Z4
THDKLLVNQTELFVP

VHLL

106

Q6RSH7
ILQDLQPFLVKTSSH

WRN

746

Q14191
PSFLSIEAKDLIHQL

PLK4

231

O00444
LTFALSVTNPLHELK

SLC39A6

11

Q13433
VLTPQFLSHDKDQLT

ACSM1

516

Q08AH1
LKDSSLLTLPNIENH

ASCC3

1956

Q8N3C0
PQSKHFSEQLLNLTL

SPG11

601

Q96JI7
KDLNHVSLSSLIPEL

VWDE

651

Q8N2E2
FINPLFLKVHSQDLS

RIN2

271

Q8WYP3
TEHYSPLSLLKQELQ

TTC13

46

Q8NBP0
TLVVAHLPFDDTNLK

TSSK4

231

Q6SA08
ELVHQQKTPNFSTLL

THOC2

1001

Q8NI27
VLFLISLTQKIPTAH

UNC80

2101

Q8N2C7
IDSFLTQHPQEIIFL

PLCXD2

146

Q0VAA5
QPIHLDSTQLSRKFI

SPC24

171

Q8NBT2
APFLSDIHNISTLKI

XRN1

486

Q8IZH2
EPFSSKSLLELEQHQ

TANGO6

616

Q9C0B7
EVSLSHKDNIIFSPL

SERPINI2

36

O75830
NKDTTHLEIEPFTLL

POLR3B

651

Q9NW08
LHNKPTFSQTIVLLN

U2AF1L4

36

Q8WU68
KPFQVDVILDLNTAH

TRIM60

291

Q495X7
LSVLKHPASLEFQAQ

SYMPK

306

Q92797
FLQLSLPTQDEKTHI

ZNF841

126

Q6ZN19
SVNSIKFHPSEQLAL

WDR37

201

Q9Y2I8
FSTKDILSQHERLLP

ZNF552

221

Q9H707
QTFIKLLLSIPHSDL

XPO7

866

Q9UIA9
VLTHSLFLPTEKFLQ

RAPGEFL1

181

Q9UHV5
NVPQEALDKLLSFTH

VWA8

626

A3KMH1
QLHEIPSLQSIYTLD

UBR4

1111

Q5T4S7
SHLKEQSLQPIDSLI

PSD3

121

Q9NYI0
HKADLLPISASVQFI

TCTN2

606

Q96GX1
QLSLPTQLEKTHIRE

ZNF836

201

Q6ZNA1
EPNLTKSQSNIHVLF

PP2D1

501

A8MPX8
LFDSQPDLLHQLVTL

KDM5C

556

P41229
LVEHVFPLLSKEQNS

LPIN2

856

Q92539
ELTDQIFTLALQHPA

MYO7B

1691

Q6PIF6
ELHLIFNNKEIFSSP

MYOM3

1036

Q5VTT5