Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

ADGRG7 GPR3 ADORA3 OR8H3 OR8B4 RXFP2 OR2D3 OR8H1 ADCYAP1R1 FFAR4

8.00e-058845210GO:0004930
GeneOntologyMolecularFunctioncentromeric DNA binding

MSH2 ZW10

1.39e-047522GO:0019237
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

ADGRG7 GPR3 ADORA3 OR8H3 FLT1 OR8B4 RXFP2 OR2D3 OR8H1 ADCYAP1R1 FFAR4

6.07e-0413535211GO:0004888
GeneOntologyMolecularFunctionchloride ion binding

ACE WNK4

7.80e-0416522GO:0031404
GeneOntologyBiologicalProcesspositive regulation of cAMP-mediated signaling

GPR3 RXFP2 ADCYAP1R1

2.58e-0523523GO:0043950
GeneOntologyBiologicalProcessmaintenance of protein location in cell

TAF8 ANKRD13C SYNE1 VPS13A

4.03e-0576524GO:0032507
GeneOntologyBiologicalProcessdetection of stimulus

OR8H3 OR8B4 PHF24 PTPRQ OR2D3 NOX3 OR8H1 NLRC4 FFAR4

7.16e-05722529GO:0051606
GeneOntologyBiologicalProcessregulation of cAMP-mediated signaling

GPR3 RXFP2 ADCYAP1R1

1.40e-0440523GO:0043949
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

ADGRG7 GPR3 ADORA3 OR8H3 OR8B4 PHF24 RXFP2 OR2D3 OR8H1 ACE ADCYAP1R1 FFAR4

1.43e-0413955212GO:0007186
GeneOntologyBiologicalProcessmaintenance of protein location

TAF8 ANKRD13C SYNE1 VPS13A

1.82e-04112524GO:0045185
GeneOntologyCellularComponentRZZ complex

KNTC1 ZW10

1.82e-053522GO:1990423
HumanPhenoSquare-wave jerks

SYNE1 VPS13A

2.42e-053152HP:0025402
HumanPhenoSaccadic intrusion

SYNE1 VPS13A

2.42e-053152HP:0032114
HumanPhenoVillous atrophy

SLC9A3 MYO5B NLRC4

4.57e-0525153HP:0011473
HumanPhenoAbnormal small intestinal villus morphology

SLC9A3 MYO5B NLRC4

4.57e-0525153HP:0011472
HumanPhenoAbnormal small intestinal mucosa morphology

SLC9A3 MYO5B NLRC4

6.48e-0528153HP:0025129
DomainGPCR_Rhodpsn_7TM

GPR3 ADORA3 OR8H3 OR8B4 RXFP2 OR2D3 OR8H1 FFAR4

4.28e-04670518IPR017452
Domain7tm_1

GPR3 ADORA3 OR8H3 OR8B4 RXFP2 OR2D3 OR8H1 FFAR4

4.59e-04677518PF00001
DomainG_PROTEIN_RECEP_F1_1

GPR3 ADORA3 OR8H3 OR8B4 RXFP2 OR2D3 OR8H1 FFAR4

4.96e-04685518PS00237
DomainG_PROTEIN_RECEP_F1_2

GPR3 ADORA3 OR8H3 OR8B4 RXFP2 OR2D3 OR8H1 FFAR4

5.25e-04691518PS50262
DomainGPCR_Rhodpsn

GPR3 ADORA3 OR8H3 OR8B4 RXFP2 OR2D3 OR8H1 FFAR4

5.30e-04692518IPR000276
DomainG_PROTEIN_RECEP_F2_2

ADGRG7 ADCYAP1R1

8.24e-0350512PS00650
Domain7tm_2

ADGRG7 ADCYAP1R1

8.24e-0350512PF00002
DomainWD40_repeat_dom

KNTC1 SCAP UBR4 ARHGEF17

8.71e-03297514IPR017986
Pubmed

Aurora B kinase-dependent recruitment of hZW10 and hROD to tensionless kinetochores.

KNTC1 ZW10

2.19e-06252218065224
Pubmed

The ZW10 and Rough Deal checkpoint proteins function together in a large, evolutionarily conserved complex targeted to the kinetochore.

KNTC1 ZW10

2.19e-06252211590237
Pubmed

Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores.

KNTC1 ZW10

2.19e-06252211146660
Pubmed

Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions.

KNTC1 ZW10

6.57e-06352212686595
Pubmed

Complex assembly, crystallization and preliminary X-ray crystallographic analysis of the human Rod-Zwilch-ZW10 (RZZ) complex.

KNTC1 ZW10

6.57e-06352225849506
Pubmed

Structure of the RZZ complex and molecular basis of its interaction with Spindly.

KNTC1 ZW10

6.57e-06352228320825
Pubmed

Tissue microarray analysis of ezrin, KBA.62, CD166, nestin, and p-Akt in melanoma versus banal and atypical nevi, and nonmelanocytic lesions.

NES ALCAM

1.31e-05452221915031
Pubmed

Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery.

KNTC1 ZW10

2.19e-05552220462495
Pubmed

PACAP/PAC1 autocrine system promotes proliferation and astrogenesis in neural progenitor cells.

NES ADCYAP1R1

3.28e-05652217115416
Pubmed

Rod/Zw10 complex is required for PIASy-dependent centromeric SUMOylation.

KNTC1 ZW10

3.28e-05652220696768
Pubmed

Interleukin-10-deficient mice develop chronic enterocolitis.

NES SLC9A3

7.84e-0595228402911
Pubmed

Novel CUL3 Variant Causing Familial Hyperkalemic Hypertension Impairs Regulation and Function of Ubiquitin Ligase Activity.

KLHL42 KLHL12 WNK4

8.71e-055752334878901
Pubmed

Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly.

KNTC1 ZW10

9.79e-051052219468067
Pubmed

14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif.

MSH2 YWHAZ

1.69e-041352222222486
Pubmed

SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.

NES SYNE1

1.97e-041452219874786
Pubmed

ZW10 links mitotic checkpoint signaling to the structural kinetochore.

KNTC1 ZW10

1.97e-041452215824131
Pubmed

Floor-plate-derived netrin-1 is dispensable for commissural axon guidance.

NES ALCAM

1.97e-041452228445456
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KNTC1 MYO5B SYNE1 UBR4 TMEM135 VPS13A ALCAM SSR3 YWHAZ

2.60e-04144252935575683
Pubmed

Loss of MYO5B in mice recapitulates Microvillus Inclusion Disease and reveals an apical trafficking pathway distinct to neonatal duodenum.

SLC9A3 MYO5B

2.60e-041652227019864
Pubmed

The thiazide-sensitive Na(+)-Cl(-) cotransporter gene, C1784T, and adrenergic receptor-beta3 gene, T727C, may be gene polymorphisms susceptible to the antihypertensive effect of thiazide diuretics.

ACE WNK4

2.60e-041652215824464
Pubmed

Olfactory receptors and signalling elements in the Grueneberg ganglion.

OR8H3 OR8H1

2.94e-041752216805845
Pubmed

Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling.

NES YWHAZ

4.09e-042052215979417
Pubmed

VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm.

NES FLT1

4.09e-042052221658587
Pubmed

Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling.

NES SSR3

5.44e-042352218728187
Pubmed

Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.

OR8H3 OR8H1

7.51e-042752232061665
Pubmed

SOSTDC1 promotes invasion and liver metastasis in colorectal cancer via interaction with ALCAM/CD166.

TLN2 ALCAM

8.08e-042852232801337
Pubmed

Deep sequencing and proteomic analysis of the microRNA-induced silencing complex in human red blood cells.

UBR4 YWHAZ

8.67e-042952225681748
Pubmed

Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.

MYRF ELOVL2

8.67e-042952221829377
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

FLT1 TLN2 ALCAM YWHAZ

8.77e-0428552421423176
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

UBR4 KLHL12 YWHAZ COG4

1.38e-0332252426514267
GeneFamilyOlfactory receptors, family 8

OR8H3 OR8B4 OR8H1

1.48e-0449383155
GeneFamilyKelch like|BTB domain containing

KLHL42 KLHL12

3.51e-0342382617
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

RANBP17 MYO5B PTPRQ ALCAM MYRF

1.83e-06174525548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RANBP17 MYO5B RXFP2 ALCAM ELOVL2

1.88e-06175525442f261a3b2c4d2523f7d4089178f8c79cac2f0f
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RANBP17 MYO5B RXFP2 ALCAM ELOVL2

1.88e-0617552535fb7735dd3355476fe60404833cb60bd066bcf1
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RANBP17 MYO5B PTPRQ ALCAM MYRF

2.41e-0618452557c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RANBP17 MYO5B PTPRQ ALCAM MYRF

2.41e-06184525d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RANBP17 MYO5B PTPRQ ALCAM MYRF

2.68e-06188525eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellCOPD-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

NES FLT1 SYNE1 TMEM135 ACE

2.68e-061885251aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RANBP17 PTPRQ ALCAM MYRF TTC6

2.89e-06191525ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RANBP17 MYO5B ALCAM MYRF TTC6

3.04e-06193525a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCelldistal-3-Epithelial-Alveolar_Epithelial_Type_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RANBP17 MYO5B PTPRQ ALCAM MYRF

3.62e-06200525ff64454a08ae8d4cc6e8f0392558460020844bbc
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

ADGRG7 FLT1 OR8H1 TTC6

2.10e-0513952464c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCellfacs-Brain_Myeloid-Cortex-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALCAM DCSTAMP ACE ELOVL2

3.14e-051545241e088b0d4a44267f46a9b643f46a1aba784686b1
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RANBP17 MYO5B ALCAM TTC6

3.56e-05159524e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KNTC1 NES PTPRQ TLN2

4.21e-051665245e3b998d740b24f790fad37350d704ca0ea10b77
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KNTC1 NES PTPRQ TLN2

4.21e-05166524bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCelldroplet-Lung-LUNG-30m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG7 ALCAM ASB2 FFAR4

4.62e-05170524ece7c20e89c190a7ec68032b6c2efeb458c43f9a
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DCSTAMP ASB2 ZW10 FFAR4

4.84e-05172524b043d4f81dced7fb3326043f68474123be47cc5d
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCSTAMP ASB2 ZW10 FFAR4

4.95e-051735246c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KNTC1 ADORA3 PHF24 DCSTAMP

5.29e-05176524581045e61cdcdfa85701343d1a7c0a72a36606a7
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 ZSWIM3 KLHL12 ASB2

5.29e-0517652427e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO5B PTPRQ ALCAM MYRF

5.41e-051775249af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellControl-Epithelial_alveolar-AT_1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO5B PTPRQ ALCAM MYRF

5.53e-05178524aa7d43c655df493f1330a5001efaa484e4a19f69
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALCAM DCSTAMP ASB2 FFAR4

5.53e-051785248c5e9fab7b55a654ccaabf2c4d02397399d94616
ToppCellControl-Epithelial_alveolar-AT_1-AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO5B PTPRQ ALCAM MYRF

5.53e-051785241817bc520f3d23da8c0fa09bba50ae703a820cb1
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

RANBP17 MYO5B PTPRQ MYRF

5.65e-051795244f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

NES FLT1 SYNE1 ACE

5.90e-05181524c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KNTC1 GPR3 NES FLT1

5.90e-051815244a225d9a6d113396c6b1d0a839bb4ca9c339a260
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

RANBP17 MYO5B ALCAM MYRF

6.16e-05183524942530449e9c6583705eeb8f6f12621daea57252
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

RANBP17 MYO5B ALCAM MYRF

6.16e-051835247b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KLHL42 ALCAM ASB2 ACE

6.16e-05183524f142b320023eef00b48d4820c46214c9794d37e7
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RANBP17 MYO5B ALCAM MYRF

6.29e-0518452429c95b814a0b1ad8734ed68b77df29c08594e5ec
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

RANBP17 MYO5B PTPRQ MYRF

6.29e-05184524561592edc3083fad41b91811151b442207c65dd9
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

RANBP17 MYO5B PTPRQ MYRF

6.42e-051855241c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

RANBP17 MYO5B PTPRQ MYRF

6.42e-0518552432b4e68e551d435a732f253f6ad83408c759a642
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

RANBP17 MYO5B PTPRQ MYRF

6.56e-0518652409d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

RANBP17 MYO5B PTPRQ MYRF

6.69e-05187524d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RANBP17 PTPRQ ALCAM MYRF

6.69e-051875244ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

RANBP17 MYO5B PTPRQ MYRF

6.69e-0518752477f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES FLT1 SYNE1 ACE

6.69e-0518752452ffd4be374e329ac8d321063f061b826d252956
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

NES FLT1 SYNE1 ACE

6.83e-05188524e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCellControl-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

NES FLT1 SYNE1 ACE

6.83e-0518852488b3415e33db81726dd29c1f50c886e057af50a0
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NES ARHGEF17 ELOVL2 ADCYAP1R1

6.83e-05188524ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYO5B VPS13A ALCAM TTC6

6.83e-05188524beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

RANBP17 MYO5B ALCAM TTC6

6.83e-05188524c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NES FLT1 ARHGEF17 ELOVL2

6.98e-051895249c2492c38f27e4c699b40680652e4c64911cce52
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NES FLT1 SYNE1 ACE

6.98e-05189524b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

RANBP17 MYO5B PTPRQ MYRF

7.12e-0519052430b50d183d7649146eb1e79b47ba897355f1998a
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RANBP17 PTPRQ ALCAM TTC6

7.12e-051905248aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCelldroplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES FLT1 SYNE1 ACE

7.12e-05190524e64b191f928935484e2c993d7f8af0572a617a3a
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_2|343B / Donor, Lineage, Cell class and subclass (all cells)

DCSTAMP ACE NLRC4 FFAR4

7.12e-051905246514f00d222eef08c282face7f177259bca62f0e
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

NES FLT1 SYNE1 ACE

7.27e-05191524f229abf69a1217194f74b0502486907e07dba989
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

RANBP17 MYO5B ALCAM TTC6

7.27e-05191524d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

RANBP17 MYO5B ALCAM TTC6

7.41e-05192524499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RANBP17 MYO5B ALCAM TTC6

7.41e-0519252429f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RANBP17 MYO5B SYNE1 ALCAM

7.72e-0519452453f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RANBP17 MYO5B SYNE1 ALCAM

7.87e-051955249406866f99555198a9be311fbd65751b70f35446
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 MYO5B PTPRQ MYRF

7.87e-05195524a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCellwk_20-22-Epithelial-Distal_epithelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RANBP17 PTPRQ ALCAM MYRF

8.03e-05196524cd507ee2baf4f52d6498811b3510d3164b56311f
ToppCellwk_20-22-Epithelial-Distal_epithelial-type_I_pneumocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RANBP17 PTPRQ ALCAM MYRF

8.03e-05196524e24a7aaf41793abba66c1189d933ca05b14c1af9
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 MYO5B PTPRQ MYRF

8.19e-051975248d5097898dd01cedb04cb694cb480c931e08462c
ToppCellBronchial-10x5prime-Stromal-Mesofibroblastic-Mesothelia|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PTPRQ MYRF WNK4 ELOVL2

8.19e-0519752426888af95a7cc082a1f1218af35b1f07cb9436ed
ToppCellBronchial-10x5prime-Stromal-Mesofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PTPRQ MYRF WNK4 ELOVL2

8.19e-05197524438de7f0d35d81d5f5e41dcef7b2c54b6da03df4
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 MYO5B ALCAM TTC6

8.51e-051995245f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 MYO5B ALCAM TTC6

8.51e-051995245cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RANBP17 MYO5B ALCAM MYRF

8.51e-05199524c1daa481f88d5281b6b5ea8ec8bb70cc0907d613
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NES FLT1 SYNE1 ACE

8.68e-052005243767abc75176779198505ebc6967d55ce322d9fe
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_CD36+_endothelial_cells|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

NES FLT1 COMMD2 ACE

8.68e-0520052446dac23d8f9d426fe52ad6dac9c15ce91e615762
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

NES SYNE1 ARHGEF17 ELOVL2

8.68e-052005248c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NES SYNE1 ASB2 ARHGEF17

8.68e-052005249169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 MYO5B ALCAM TTC6

8.68e-05200524d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_3|Control_saline / Treatment groups by lineage, cell group, cell type

NES SYNE1 ASB2 ARHGEF17

8.68e-05200524b0866b497aa71d06cef25f9a335fa584e95fa7e0
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MYO5B PTPRQ ALCAM MYRF

8.68e-05200524cbe3e107ac16c17687d73ebb04c39d51aba1fa98
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NES SYNE1 ASB2 ARHGEF17

8.68e-05200524c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RANBP17 MYO5B ALCAM TTC6

8.68e-052005240eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_only / Treatment groups by lineage, cell group, cell type

NES SYNE1 ARHGEF17 ELOVL2

8.68e-052005247c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRQ RXFP2 ADCYAP1R1

2.88e-04110523c80d1c3df75648e2c8f6832279c2acca63d76681
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO5B MYRF TTC6

4.70e-041305236434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT1|E18.5-samps / Age Group, Lineage, Cell class and subclass

MYO5B PTPRQ MYRF

4.70e-04130523eb16a8f8f62add5fdd29c78d4608b6d1a06767f1
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-4|TCGA-Kidney / Sample_Type by Project: Shred V9

RANBP17 ADGRG7 TAF8

5.47e-04137523758aa466a01265ed67b94f1578b4099956506271
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RXFP2 ASB2 FFAR4

5.83e-041405232c44e8cc5190226049be7ebc465d685393e701c4
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 TLN2 ACE

6.33e-041445231b9e95e4f6e40042d3cf2f94c067f3a6b19428ea
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TTLL11 TLN2 ZW10

6.45e-0414552334fc6da04d4fe0817e37cdcd844fe2a6e53a4796
ToppCell15-Trachea-Immune-Immune|Trachea / Age, Tissue, Lineage and Cell class

ASB2 NLRC4 FFAR4

6.58e-04146523ca722a89c6601e78f253d9484d01931f26161820
ToppCellLPS-antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RANBP17 MYO5B PTPRQ

7.12e-041505239cb3332924bd67c966873343c14445e30d3f384f
ToppCellsevere_COVID-19-NK_CD56bright|World / disease group, cell group and cell class (v2)

ADORA3 ZSWIM3 WNK4

7.40e-04152523ab5a4e47b23d16018642d4c9c7f41b30205edf73
ToppCelldroplet-Lung-nan-3m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 PHF24 DCSTAMP

7.40e-0415252377b319f594d5e4df29034bbf69c7490076f89dd3
ToppCellCOVID-19_Severe-multiplets|COVID-19_Severe / disease group, cell group and cell class

SYNE1 ASB2 MYRF

7.40e-04152523451745151322c2fcea22dbb3dba681e12634a510
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TLN2 ASB2 WNK4

7.54e-041535231524557514668f515ac1bbe847611f564b265b42
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE1 TLN2 MYRF

7.69e-04154523e94cd11488003347120eacd3ced0a8923ed09ccc
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 SYNE1 ELOVL2

7.83e-041555235d157478669b609e1f0f0a75afd0112571fc2c46
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|390C / Donor, Lineage, Cell class and subclass (all cells)

ZSWIM3 UBR4 ALCAM

7.83e-0415552315bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_2|367C / Donor, Lineage, Cell class and subclass (all cells)

TTLL11 ALCAM FFAR4

7.98e-041565231a0e081284a99c1b345990775015b8a2fa469496
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ELOVL2 FFAR4

7.98e-04156523ea9223bb6450b22df11efa1705ab72dab005244a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ELOVL2 FFAR4

7.98e-04156523586b5509074c4cc359e9e31a968c2ded71c994ca
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NES ELOVL2 ADCYAP1R1

8.28e-04158523c736834269c89e003c61a62b63e4e50dbf0e1538
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 PTPRQ TLN2

8.43e-041595237619d0d49738dd08daf01b42664691a5323aa793
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 PTPRQ TLN2

8.43e-041595234000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-CD1c+_DCs|Myeloid_cells / Location, Cell class and cell subclass

GPR3 TCTN3 ASB2

8.43e-04159523b3c52908cd24bbf851fac69db3850fc7f53c2092
ToppCellControl-Endothelial_cells-Inflamed_endothelial_cells|Control / group, cell type (main and fine annotations)

NES FLT1 ACE

8.58e-04160523958256e3d3836160763b82bb48f794087918d935
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG7 ADORA3 FFAR4

8.58e-04160523e9e52532131cdc3fb01e81cfc046e3f670cc8e75
Disease1-docosahexaenoyl-GPC (22:6) measurement

MYRF ELOVL2

8.78e-063512EFO_0800244
Diseasenisinate (24:6n3) measurement

MYRF ELOVL2

2.92e-055512EFO_0800536
Diseasecholesteryl ester 24:6 measurement

MYRF ELOVL2

4.37e-056512EFO_0021449
Disease1-palmitoyl-2-docosahexaenoyl-GPC (16:0/22:6) measurement

MYRF ELOVL2

6.12e-057512EFO_0800391
Disease1-stearoyl-2-docosahexaenoyl-GPC (18:0/22:6) measurement

MYRF ELOVL2

8.15e-058512EFO_0800392
Diseasealpha wave measurement, electroencephalogram measurement

NOX3 MSH2

1.31e-0410512EFO_0004357, EFO_0006870
Diseaseplacenta growth factor measurement

FLT1 WNK4

1.59e-0411512EFO_0010626
DiseaseDiarrhea

SLC9A3 MYO5B

1.59e-0411512C0011991
Diseaselysophosphatidylcholine 22:5 measurement

MYRF ELOVL2

2.63e-0414512EFO_0021462
DiseasePre-Eclampsia

FLT1 ACE

3.46e-0416512C0032914
Diseaserenovascular hypertension (biomarker_via_orthology)

SLC9A3 ACE

4.92e-0419512DOID:1591 (biomarker_via_orthology)
Diseasediacylglycerol 38:5 measurement

MYRF ELOVL2

4.92e-0419512EFO_0020067
Diseaseesterified cholesterol measurement, high density lipoprotein cholesterol measurement

MYO5B MYRF

4.92e-0419512EFO_0004612, EFO_0008589
Diseasepulmonary non-tuberculous mycobacterial infection

FLT1 SCAP

4.92e-0419512MONDO_0018469
Diseasephosphatidylinositol measurement

MYRF ELOVL2 TTC6

6.02e-0495513EFO_0010230
Diseasenephrosis (biomarker_via_orthology)

NES ACE

6.62e-0422512DOID:2527 (biomarker_via_orthology)
Diseasepre-eclampsia (is_implicated_in)

FLT1 ACE

8.57e-0425512DOID:10591 (is_implicated_in)
Diseasedocosapentaenoic acid measurement

MYRF ELOVL2

1.00e-0327512EFO_0006809
DiseaseCerebral Hemorrhage

FLT1 ACE

1.08e-0328512C2937358
Diseasecerebral infarction (is_implicated_in)

ACE MYRF

1.15e-0329512DOID:3526 (is_implicated_in)
Diseaseeicosapentaenoic acid measurement

MYRF ELOVL2

1.32e-0331512EFO_0007760
Diseasecholesteryl ester 22:6 measurement

MYRF ELOVL2

1.41e-0332512EFO_0010350
Diseaseliver cirrhosis (biomarker_via_orthology)

FLT1 ACE

1.59e-0334512DOID:5082 (biomarker_via_orthology)
Diseasegranulocyte colony-stimulating factor measurement

ANKRD13C PHF24

1.59e-0334512EFO_0008142
Diseasephosphatidylcholine 38:2 measurement

TTLL11 MYRF

1.68e-0335512EFO_0010384

Protein segments in the cluster

PeptideGeneStartEntry
NKILLDMETTYSVAT

ACE

741

P12821
TALSLANVTYITMEI

ADORA3

6

P0DMS8
LYSSLSEDELVQMAI

ASB2

21

Q96Q27
IYDSLTGLMTSLVAV

COG4

671

Q9H9E3
EVDILMSSDIYSATL

ANKRD13C

316

Q8N6S4
LTTLIEQMETYSLSL

ADGRG7

231

Q96K78
LMYVLTSISEGLTTL

RANBP17

911

Q9H2T7
TMLSSISIVISYALI

OR8B4

206

Q96RC9
AMTLLDTEQSYVESL

ARHGEF17

1071

Q96PE2
VLSLSMLSITYHSSI

KIAA0100

641

Q14667
KMVSISDITSTYSSL

NLRC4

476

Q9NPP4
YVMTLSGSVTILTLA

FFAR4

116

Q5NUL3
TYLLTESSKLMISEL

COMMD2

66

Q86X83
VLYQMATTTEVLSSL

DCSTAMP

196

Q9H295
LKMSLSLEVATYRTL

NES

291

P48681
MEILYSLEVSSVSSL

KNTC1

341

P50748
LKLASIDTYSTEMAI

OR2D3

201

Q8NGH3
TKEMLLLSITTAYTG

MFSD11

236

O43934
SETTVTRTYVMLALV

GPR3

146

P46089
YSTSLVTLTTAMVIL

ADCYAP1R1

161

P41586
TLMVSLITISASYVS

OR8H3

206

Q8N146
MTVSTIIDKLTIFSY

PTPRQ

1051

Q9UMZ3
ASTMEILLDFVYTET

KLHL12

81

Q53G59
TLLSAYMLAELILST

ELOVL2

76

Q9NXB9
AITTVYIDQTMVLAS

SCAP

1121

Q12770
MIASTAITVHYLDLS

ALCAM

321

Q13740
HVTALTTEETLTMLY

MSH2

801

P43246
LMVSLITISASYVSI

OR8H1

206

Q8NGG4
SLLYVMGVLSSSEEL

MROH5

221

Q6ZUA9
ASVETLTEMLQSYIS

TAF8

56

Q7Z7C8
SELEAMTEKLQYLTS

SYNE1

5581

Q8NF91
LSYLTSEMLSLSAIL

SLC9A3

296

P48764
IDLTELITFASSLAM

SPATA32

236

Q96LK8
LAMLSTEVSVLLLTY

RXFP2

501

Q8WXD0
SLALVLIMTSSTEFI

NOX3

181

Q9HBY0
INLLLTEEEMYSLTE

PHF24

191

Q9UPV7
IQSAVLYSVMTLVST

SSR3

56

Q9UNL2
LSEESYKDSTLIMQL

YWHAZ

206

P63104
SLSMAAVDILYIDIT

TTLL11

676

Q8NHH1
VIINTMITITSALYT

VPS13A

1656

Q96RL7
MITITSALYTTKETI

VPS13A

1661

Q96RL7
TYTLTDLMNEIKESS

USP45

211

Q70EL2
YKLAITDLTTAISMD

TTC6

121

Q86TZ1
STTISMYLASKLVET

TMEM135

346

Q86UB9
YMDSLDIVTSKVSSL

ZSWIM3

391

Q96MP5
ILVSAKTMLESSSYL

TLN2

1601

Q9Y4G6
LLALTDDISYSMTLL

TCTN3

391

Q6NUS6
SSSEIKTDYLSIIMD

FLT1

786

P17948
SSLQYEMLLLTDSIS

UBR4

3966

Q5T4S7
VLVTELMTSGTLKTY

WNK4

251

Q96J92
LMELAYQTLLEATTS

ZW10

486

O43264
IYIMSRDVTLSTSLE

KLHL42

451

Q9P2K6
LVTTSETYVKTMSLQ

MYO5B

381

Q9ULV0
VSMSTLYVLSLRTEE

MYRF

781

Q9Y2G1