Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenodecreased corpus callosum size

ANK2 CLIP2 MYCBP2 AFF3 SHTN1 THOC2 ULK4

5.60e-0947767MP:0000781
MousePhenoabnormal corpus callosum size

ANK2 CLIP2 MYCBP2 AFF3 SHTN1 THOC2 ULK4

1.16e-0852767MP:0020573
MousePhenoabnormal corpus callosum morphology

ANK2 CLIP2 MYCBP2 AFF3 MARCKSL1 SHTN1 THOC2 ULK4 MARCKS

3.10e-08129769MP:0000780
MousePhenoabnormal dorsal telencephalic commissure morphology

ANK2 CLIP2 MYCBP2 AFF3 MARCKSL1 SHTN1 THOC2 ULK4 MARCKS

3.79e-08132769MP:0008219
MousePhenoabnormal brain commissure morphology

ANK2 CLIP2 MYCBP2 AFF3 MARCKSL1 SHTN1 THOC2 ULK4 MARCKS

2.10e-07161769MP:0002199
MousePhenoabnormal nervous system tract morphology

ANK2 CLIP2 MYCBP2 AFF3 MARCKSL1 SHTN1 THOC2 ULK4 MARCKS

8.15e-07189769MP:0000778
MousePhenoabnormal brain white matter morphology

ANK2 CLIP2 MYCBP2 AFF3 MARCKSL1 SHTN1 THOC2 ULK4 MARCKS

1.67e-06206769MP:0008026
MousePhenoabnormal brain ventricle morphology

ANK2 CLIP2 MYCBP2 AFF3 MARCKSL1 ATXN1 TET1 ULK4 MARCKS

2.38e-05286769MP:0000822
MousePhenodilated brain ventricle

CLIP2 MYCBP2 ATXN1 ULK4 MARCKS

1.41e-0492765MP:0012676
MousePhenoabnormal classified tumor incidence

CYLD SMG1 ASXL1 PRDM2 PTPRZ1 TET1 PAK1 KMT2A TP53BP1

2.27e-04384769MP:0020188
MousePhenoabnormal brain ventricular system morphology

ANK2 CLIP2 MYCBP2 AFF3 MARCKSL1 ATXN1 TET1 ULK4 MARCKS

2.70e-04393769MP:0002200
DomainCCDC74_C

CCDC74B CCDC74A

2.78e-052992PF14917
DomainCCDC74

CCDC74B CCDC74A

2.78e-052992IPR033226
DomainMARCKS_1

MARCKSL1 MARCKS

2.78e-052992PS00826
DomainMARCKS_2

MARCKSL1 MARCKS

2.78e-052992PS00827
DomainCCDC74_C

CCDC74B CCDC74A

2.78e-052992IPR029422
DomainMARCKS

MARCKSL1 MARCKS

2.78e-052992IPR002101
DomainMARCKS

MARCKSL1 MARCKS

2.78e-052992PF02063
Domainzf-C2H2_6

ZNF845 ZNF391 ZNF813 PRDM2 ZNF8 ZNF600 ZNF611 ZNF808 ZNF701

4.40e-05314999PF13912
DomainTF_AF4/FMR2

AFF3 AFF4

1.66e-044992IPR007797
DomainAF-4

AFF3 AFF4

1.66e-044992PF05110
DomainZnf_C2H2-like

ZNF845 ZNF391 ZNF813 PRDM2 ZNF8 ZC3H7A ZNF600 ZNF611 ZNF638 ZNF808 ZNF701 ZNF292

1.02e-037969912IPR015880
DomainZnf_C2H2

ZNF845 ZNF391 ZNF813 PRDM2 ZNF8 ZC3H7A ZNF600 ZNF611 ZNF638 ZNF808 ZNF701 ZNF292

1.12e-038059912IPR007087
DomainZnF_C2H2

ZNF845 ZNF391 ZNF813 PRDM2 ZNF8 ZC3H7A ZNF600 ZNF611 ZNF638 ZNF808 ZNF701 ZNF292

1.16e-038089912SM00355
DomainCAP_GLY

CYLD CLIP2

1.22e-0310992PF01302
DomainCAP_GLY_1

CYLD CLIP2

1.22e-0310992PS00845
DomainCAP_GLY_2

CYLD CLIP2

1.22e-0310992PS50245
DomainCAP-Gly_domain

CYLD CLIP2

1.22e-0310992IPR000938
DomainCAP_GLY

CYLD CLIP2

1.22e-0310992SM01052
Domain-

CYLD CLIP2

1.22e-03109922.30.30.190
DomainZnf_CXXC

TET1 KMT2A

1.48e-0311992IPR002857
DomainZF_CXXC

TET1 KMT2A

1.48e-0311992PS51058
Domainzf-CXXC

TET1 KMT2A

1.48e-0311992PF02008
DomainZINC_FINGER_C2H2_2

ZNF845 ZNF391 ZNF813 PRDM2 ZNF8 ZC3H7A ZNF600 ZNF611 ZNF808 ZNF701 ZNF292

2.66e-037759911PS50157
DomainZINC_FINGER_C2H2_1

ZNF845 ZNF391 ZNF813 PRDM2 ZNF8 ZC3H7A ZNF600 ZNF611 ZNF808 ZNF701 ZNF292

2.71e-037779911PS00028
DomainKRAB

ZNF845 ZNF321P ZNF813 ZNF8 ZNF611 ZNF808 ZNF701

2.95e-03358997PS50805
DomainKRAB

ZNF845 ZNF321P ZNF813 ZNF8 ZNF611 ZNF808 ZNF701

2.95e-03358997PF01352
Domain-

ZNF845 ZNF391 ZNF813 PRDM2 ZNF8 ZNF600 ZNF611 ZNF808 ZNF701 ZNF292

3.21e-0367999103.30.160.60
DomainKRAB

ZNF845 ZNF321P ZNF813 ZNF8 ZNF611 ZNF808 ZNF701

3.49e-03369997SM00349
DomainKRAB

ZNF845 ZNF321P ZNF813 ZNF8 ZNF611 ZNF808 ZNF701

3.54e-03370997IPR001909
Domainzf-C2H2

ZNF845 ZNF391 ZNF813 PRDM2 ZNF8 ZNF600 ZNF611 ZNF808 ZNF701 ZNF292

3.70e-036939910PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF845 ZNF391 ZNF813 PRDM2 ZNF8 ZNF600 ZNF611 ZNF808 ZNF701 ZNF292

3.74e-036949910IPR013087
DomainAnk_2

ANKRD31 ANK2 BCORL1 ASB15 ANKRD33B

5.75e-03215995PF12796
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

CYLD SMG1 ASXL1 CLIP2 MYCBP2 SIPA1L3 PSD3 TNRC6C ADCY9 GPR158 CEP72

9.51e-112251051112168954
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

CCDC14 CYLD MYCBP2 PARP2 BCORL1 NCBP1 SHTN1 THOC2 ZNF8 CEP72 ZNF638 NAV1 KMT2A KDM1B

9.64e-096451051425281560
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

ABCC3 ABI1 ANK2 TMEM199 PSD3 MARCKSL1 ADCY9 GPR158 BSG MICAL2 NAV1 DCUN1D3 MARCKS

1.86e-085691051330639242
Pubmed

Human transcription factor protein interaction networks.

CYLD SMG1 ASXL1 BCORL1 MAML1 CEP192 TNRC6C NKRF PRDM2 ATXN1 BSG TLE3 ZNF611 ZNF638 KMT2A KDM1B RBM34 TP53BP1 RAVER1

5.16e-0814291051935140242
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

SMG1 ABCC3 NYAP2 WDR64 BCORL1 MAML1 NBEA DSN1 CEP72 TLE3 HFM1 RBM34 RAVER1

7.04e-086381051331182584
Pubmed

MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.

AFF3 CCNT1 KMT2A AFF4

7.67e-0814105420854876
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TIGAR MYCBP2 SIPA1L3 AFF3 PTDSS1 SRCIN1 CEP192 TNRC6C SHTN1 TASOR2 ATXN1 GPR158 MICAL2 TLE3 ZNF638 NAV1 CSMD1 AFF4 RAVER1

9.80e-0814891051928611215
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

USP36 ABI1 SIPA1L3 PARP2 PTDSS1 MAML1 SRPK1 ABCF2 MARCKSL1 CGGBP1 N4BP3 NKRF JARID2 CCNT1 ZC3H7A KMT2A KDM1B MARCKS AFF4

1.06e-0714971051931527615
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CYLD ABI1 NYAP2 ANK2 CLIP2 MYCBP2 SIPA1L3 NBEA SHTN1 CCDC13 GPR158 PAK1 NAV1 AFF4 TP53BP1

2.12e-079631051528671696
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ZNF845 BCORL1 ZNF813 NCBP1 PRDM2 ZNF8 CCNT1 KMT2A KDM1B AFF4 RBM34 ZNF292

3.26e-076081051236089195
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CYLD ABI1 SASH1 MYCBP2 KIF26B SIPA1L3 PSD3 CEP192 N4BP3 SHTN1 ATXN1 TET1 NAV1 KMT2A

3.34e-078611051436931259
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CCDC14 USP36 MYCBP2 SIPA1L3 PSD3 NCBP1 NBEA CEP192 ADCY9 CEP72 BSG PTPRZ1 TLE3 ZNF638 RAVER1

6.23e-0710491051527880917
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

NBEA CEP192 TNRC6C SHTN1 TLE3 CADPS2

6.58e-07101105610997877
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

ABI1 ANK2 CLIP2 MYCBP2 NBEA SRCIN1 ADCY9 PAK1 MARCKS

1.14e-06347105917114649
Pubmed

Combinatorial CRISPR screen identifies fitness effects of gene paralogues.

USP36 SMG1 PARP2 DSN1 CCNT1 NAV1 KMT2A

1.63e-06186105733637726
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

CYLD ABI1 NYAP2 FRMPD4 ANK2 MYCBP2 PSD3 NBEA MARCKSL1 SRCIN1 GPR158 BSG NAV1 MARCKS TP53BP1

1.73e-0611391051536417873
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CYLD TIGAR TBC1D15 ANK2 MYCBP2 TMEM199 PTDSS1 PSD3 SRPK1 MARCKSL1 CEP192 ADCY9 ZC3H7A BSG MARCKS RBM34 TP53BP1

2.26e-0614871051733957083
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

SASH1 KIF26B TMEM199 PSD3 MARCKSL1 ADCY9 BSG DCUN1D3 MARCKS

2.26e-06377105938117590
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

ASXL1 MYCBP2 BCORL1 DSN1 JARID2 CEP72 TET1 KMT2A KDM1B ZNF292

2.69e-064951051027705803
Pubmed

A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.

CCNT1 KMT2A AFF4

3.16e-0610105320153263
Pubmed

CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis.

CCNT1 KMT2A AFF4

3.16e-0610105322094252
Pubmed

Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice.

MARCKSL1 PTPRZ1 MARCKS

3.16e-061010539184108
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CYLD ASXL1 FRMPD4 TRO PSD3 CEP192 TNRC6C TLE3 NAV1

4.21e-06407105912693553
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TBC1D15 MYCBP2 BCORL1 SHTN1 PRDM2 ZNF8 TLE3 TET1 NAV1

5.22e-06418105934709266
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

USP36 AFF3 MAML1 NKRF CCNT1 POLQ AFF4

5.26e-06222105737071664
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SIPA1L3 PARP2 SRPK1 ABCF2 NCBP1 THOC2 NKRF PPL TASOR2 BSG ZNF638 NAV1 MARCKS RBM34 RAVER1

5.71e-0612571051536526897
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SMG1 ANK2 TRO SIPA1L3 BIVM ABCF2 NCBP1 PPL TASOR2 ZC3H7A BSG KMT2A CADPS2 POLQ CCDC191 ZNF292

6.77e-0614421051635575683
Pubmed

Genomic breakpoints and clinical features of MLL-TET1 rearrangement in acute leukemias.

TET1 KMT2A

9.03e-062105223100278
Pubmed

Fusion of an AF4-related gene, LAF4, to MLL in childhood acute lymphoblastic leukemia with t(2;11)(q11;q23).

AFF3 KMT2A

9.03e-062105212743608
Pubmed

LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23).

TET1 KMT2A

9.03e-062105212124344
Pubmed

LAF4, an AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia.

AFF3 KMT2A

9.03e-062105212203795
Pubmed

Suppression of the lipopolysaccharide-induced expression of MARCKS-related protein (MRP) affects transmigration in activated RAW264.7 cells.

MARCKSL1 MARCKS

9.03e-062105219246034
Pubmed

Haploinsufficiency of two histone modifier genes on 6p22.3, ATXN1 and JARID2, is associated with intellectual disability.

JARID2 ATXN1

9.03e-062105223294540
Pubmed

The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group.

TET1 KMT2A

9.03e-062105219144982
Pubmed

ABI-1, a human homolog to mouse Abl-interactor 1, fuses the MLL gene in acute myeloid leukemia with t(10;11)(p11.2;q23).

ABI1 KMT2A

9.03e-06210529694699
Pubmed

First description of the t(10;11)(q22;q23)/MLL-TET1 translocation in a T-cell lymphoblastic lymphoma, with subsequent lineage switch to acute myelomonocytic myeloid leukemia.

TET1 KMT2A

9.03e-062105224323992
Pubmed

A cell motility screen reveals role for MARCKS-related protein in adherens junction formation and tumorigenesis.

MARCKSL1 MARCKS

9.03e-062105219924305
Pubmed

The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat.

CCNT1 AFF4

9.03e-062105223471103
Pubmed

MacMARCKS, a novel member of the MARCKS family of protein kinase C substrates.

MARCKSL1 MARCKS

9.03e-06210521516135
Pubmed

The regulation of MacMARCKS expression by integrin beta3.

MARCKSL1 MARCKS

9.03e-062105217292354
Pubmed

MARCKS deficiency in mice leads to abnormal brain development and perinatal death.

MARCKSL1 MARCKS

9.03e-06210527862670
Pubmed

Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex.

CCNT1 AFF4

9.03e-062105227731797
Pubmed

jumonji gene maps to mouse chromosome 13.

JARID2 ATXN1

9.03e-06210529339385
Pubmed

Is t(10;11)(p11.2;q23) involving MLL and ABI-1 genes associated with congenital acute monocytic leukemia?

ABI1 KMT2A

9.03e-062105212547160
Pubmed

CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment.

CCDC74B CCDC74A

9.03e-062105231521166
Pubmed

Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.

CGGBP1 SHTN1 ZNF8 TLE3 ZNF638 TP53BP1

1.14e-05165105616107646
Pubmed

Proximity interactions among centrosome components identify regulators of centriole duplication.

CCDC14 CYLD MYCBP2 CEP192 CEP72

1.43e-05101105524613305
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

MAML1 CCNT1 ATXN1 TLE3 KMT2A AFF4 RAVER1

1.78e-05268105733640491
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

USP36 ANK2 THOC2 TASOR2 CCNT1 ZNF638 TP53BP1

1.92e-05271105732433965
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

CCDC14 SIPA1L3 CEP192 ATXN1 NAV1 RAVER1

2.11e-05184105632908313
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

SIPA1L3 SRPK1 ABCF2 NCBP1 MARCKSL1 THOC2 NKRF CCNT1 BSG MICAL2 PAK1 DCUN1D3 AFF4 RAVER1

2.37e-0512471051427684187
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

USP36 CYLD MAML1 NBEA MARCKSL1 CEP192 ADCY9 PPL TASOR2 ZNF638 MARCKS

2.39e-057771051135844135
Pubmed

MiR-1261/circ-PTPRZ1/PAK1 pathway regulates glioma cell growth and invasion.

PTPRZ1 PAK1

2.70e-053105231364003
Pubmed

MCEF, the newest member of the AF4 family of transcription factors involved in leukemia, is a positive transcription elongation factor-b-associated protein.

CCNT1 AFF4

2.70e-053105212065898
Pubmed

Functional characterization of the AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability.

AFF3 AFF4

2.70e-053105221330300
Pubmed

TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23).

TET1 KMT2A

2.70e-053105212646957
Pubmed

Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4.

CCNT1 AFF4

2.70e-053105224727379
Pubmed

PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1.

ATXN1 PAK1

2.70e-053105229860311
Pubmed

AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23).

KMT2A AFF4

2.70e-053105210588740
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

ZNF845 MYCBP2 BCORL1 MAML1 CGGBP1 THOC2 PRDM2 CCNT1 TLE3 KMT2A TP53BP1 ZNF292 RAVER1

2.88e-0511031051334189442
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYCBP2 SRPK1 NCBP1 THOC2 NKRF TASOR2 ZNF638 KMT2A RBM34 TP53BP1

2.96e-056531051022586326
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

USP36 ZNF845 BCORL1 THOC2 NKRF TASOR2 CCNT1 ZNF638 KMT2A ZNF808 AFF4 TP53BP1

3.19e-059541051236373674
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CYLD ANK2 CLIP2 MYCBP2 SIPA1L3 NCBP1 NBEA SHTN1 CCDC13 MICAL2 PAK1 CADPS2 AFF4 ZNF292

3.28e-0512851051435914814
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

PSD3 MARCKSL1 ADCY9 GPR158 BSG CADPS2 DCUN1D3 MARCKS

3.29e-05405105838187761
Pubmed

High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.

MYCBP2 MAML1 MARCKSL1 TNRC6C BSG MARCKS RAVER1

4.24e-05307105737499664
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

TBC1D15 MYCBP2 SHTN1 THOC2 NKRF MTRF1 TET1 KMT2A TP53BP1

4.47e-05549105938280479
Pubmed

The protein interaction landscape of the human CMGC kinase group.

ASXL1 SIPA1L3 AFF3 SRPK1 MARCKSL1 CCNT1 TLE3 NAV1 AFF4 RBM34

4.99e-056951051023602568
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

CLIP2 PTDSS1 SRPK1 ABCF2 NCBP1 THOC2 NKRF CCNT1 ZNF638 KMT2A RBM34

5.22e-058471051135850772
Pubmed

Isolation, characterization, and mapping of the mouse Fgd3 gene, a new Faciogenital Dysplasia (FGD1; Aarskog Syndrome) gene homologue.

ATXN1 FGD3

5.40e-054105210721717
Pubmed

Identification of MLL-fusion/MYC⊣miR-26⊣TET1 signaling circuit in MLL-rearranged leukemia.

TET1 KMT2A

5.40e-054105226791235
Pubmed

Mouse neuron navigator 1, a novel microtubule-associated protein involved in neuronal migration.

CLIP2 NAV1

5.40e-054105215797708
Pubmed

Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice.

AFF3 AFF4

5.40e-054105211923441
Pubmed

Differential chromatin looping regulates CD4 expression in immature thymocytes.

CCNT1 AFF4

5.40e-054105218039856
Pubmed

HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold.

CCNT1 AFF4

5.40e-054105223251033
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

CYLD NYAP2 CLIP2 SIPA1L3 SRCIN1 TNRC6C

5.44e-05218105633378226
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

ABI1 SIPA1L3 TMEM199 SRCIN1 SHTN1 ADCY9 PPL BSG MARCKS

5.58e-05565105925468996
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

ANK2 CLIP2 SIPA1L3 SRPK1 NCBP1 MARCKSL1 CGGBP1 THOC2 NKRF KMT2A DCUN1D3 MARCKS AFF4 RBM34

6.60e-0513711051436244648
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

USP36 SRPK1 NCBP1 NKRF GLE1 ZNF638 RBM34

6.93e-05332105725693804
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ZNF845 TBC1D15 PTDSS1 ZNF813 ABCF2 NCBP1 THOC2 CCNT1 BSG MICAL2 GLE1 ZNF808 TP53BP1

6.97e-0512031051329180619
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

NKRF CCNT1 TLE3 ZNF638 KMT2A AFF4 TP53BP1

8.19e-05341105732971831
Pubmed

Forced expression of NESH suppresses motility and metastatic dissemination of malignant cells.

ABI1 PAK1

8.97e-055105211956071
Pubmed

Reactive oxygen species-dependent down-regulation of tumor suppressor genes PTEN, USP28, DRAM, TIGAR, and CYLD under oxidative stress.

CYLD TIGAR

8.97e-055105223832602
Pubmed

Interaction network of human early embryonic transcription factors.

BCORL1 MAML1 PRDM2 ATXN1 TLE3 TET1 KMT2A

9.80e-05351105738297188
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

TBC1D15 SRPK1 MARCKSL1 SRCIN1 PAK1 MARCKS

1.06e-04246105615345747
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

MYCBP2 PTDSS1 NCBP1 CGGBP1 THOC2 NKRF ZNF8 ZNF638 KDM1B MARCKS AFF4 ZNF292

1.06e-0410821051238697112
Pubmed

A human MAP kinase interactome.

CCDC14 CLIP2 KIF26B ZC3H7A ZNF600 ATXN1 PAK1 NAV1

1.17e-04486105820936779
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

PARP2 SRPK1 NCBP1 ZNF638 KMT2A TP53BP1

1.18e-04251105631076518
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

USP36 ANK2 SHTN1 THOC2 NKRF CCNT1 ZNF638 KMT2A MARCKS AFF4 TP53BP1

1.24e-049341051133916271
Pubmed

Characteristics of the F52 protein, a MARCKS homologue.

MARCKSL1 MARCKS

1.34e-04610521618855
Pubmed

Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.

CCNT1 KMT2A

1.34e-046105221896721
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NBEA LPIN1 GPR158 ZNF292

1.44e-0487105412465718
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

TBC1D15 THOC2 ZNF8 TLE3 PAK1 ZNF638 TP53BP1 RAVER1

1.48e-04503105816964243
Pubmed

SKIP interacts with c-Myc and Menin to promote HIV-1 Tat transactivation.

CCNT1 KMT2A

1.88e-047105219818711
Pubmed

Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation.

CCNT1 KDM1B

1.88e-047105220670891
Pubmed

Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.

ABI1 ANK2 CLIP2

1.93e-0437105327565344
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP36 SMG1 NYAP2 SASH1 MAML1 SRCIN1 ADCY9 TET1

2.08e-04529105814621295
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF845 ZNF813 ZNF8 ZNF611 ZNF701

2.29e-04181105537372979
Pubmed

Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.

ABCF2 THOC2 NKRF CCNT1 ZNF701

2.35e-04182105532239614
Pubmed

Developmental expression of MARCKS and protein kinase C in mice in relation to the exencephaly resulting from MARCKS deficiency.

MARCKSL1 MARCKS

2.50e-04810528922669
Pubmed

The mutational landscape of lethal castration-resistant prostate cancer.

ASXL1 KMT2A

2.50e-048105222722839
InteractionPFN1 interactions

USP36 CYLD ABI1 ANK2 SRPK1 NBEA CEP192 SHTN1 CCNT1 NAV1 MARCKS AFF4 TP53BP1

1.76e-0650910213int:PFN1
InteractionCEP135 interactions

CCDC14 CYLD SIPA1L3 SRPK1 CEP192 TNRC6C IQCC CEP72 NAV1

9.98e-062721029int:CEP135
InteractionKRT8 interactions

CCDC14 CYLD SMG1 SIPA1L3 CEP192 TNRC6C PPL MTRF1 CEP72 BSG NAV1

1.45e-0544110211int:KRT8
InteractionKDM1A interactions

CCDC14 CCDC74B TBC1D15 MYCBP2 BCORL1 SHTN1 THOC2 PRDM2 ZNF8 ATXN1 TLE3 TET1 CCDC74A NAV1 KDM1B TP53BP1

1.96e-0594110216int:KDM1A
InteractionYWHAZ interactions

CYLD ASXL1 ABI1 SASH1 CLIP2 MYCBP2 KIF26B SIPA1L3 PSD3 CEP192 N4BP3 SHTN1 ATXN1 PAK1 ZNF638 NAV1 KMT2A MARCKS TP53BP1

3.04e-05131910219int:YWHAZ
InteractionADARB1 interactions

USP36 ZNF845 ANK2 SRPK1 THOC2 NKRF CCNT1 GLE1 ZNF638 RBM34 TP53BP1

3.74e-0548910211int:ADARB1
InteractionH3C3 interactions

ZNF845 BCORL1 ZNF813 NCBP1 PRDM2 ZNF8 KMT2A KDM1B AFF4 RBM34 ZNF292

4.18e-0549510211int:H3C3
InteractionBCLAF1 interactions

CYLD ASXL1 ABI1 MYCBP2 SRPK1 THOC2 JARID2 ATXN1 GLE1

4.26e-053271029int:BCLAF1
InteractionH3C1 interactions

USP36 ANK2 PARP2 SRPK1 PRDM2 ATXN1 TLE3 PAK1 ZNF638 KMT2A KDM1B AFF4 RBM34 TP53BP1 ZNF292

4.66e-0590110215int:H3C1
InteractionYWHAG interactions

CYLD ABI1 SASH1 MYCBP2 KIF26B SIPA1L3 PSD3 SRPK1 CEP192 N4BP3 SHTN1 LPIN1 ATXN1 TET1 PAK1 ZNF638 NAV1 KMT2A

5.00e-05124810218int:YWHAG
InteractionTNRC6C interactions

CYLD CEP192 TNRC6C ZC3H7A IQCC RAVER1

7.26e-051381026int:TNRC6C
InteractionSYNE3 interactions

CCDC14 CYLD SIPA1L3 CEP192 TNRC6C ADCY9 IQCC CEP72 NAV1 RAVER1

8.51e-0544410210int:SYNE3
InteractionCNOT3 interactions

NBEA TNRC6C THOC2 ZC3H7A ATXN1 MARCKS RAVER1

8.82e-052071027int:CNOT3
InteractionZNF330 interactions

USP36 SEMG1 BCORL1 SRPK1 NKRF ZNF8 KMT2A AFF4 RBM34 ZNF292

8.83e-0544610210int:ZNF330
InteractionAP2B1 interactions

USP36 CYLD SIPA1L3 CEP192 TNRC6C ATXN1 BSG NAV1 AFF4

1.17e-043731029int:AP2B1
InteractionCENPA interactions

USP36 PARP2 BCORL1 THOC2 DSN1 PRDM2 KMT2A RBM34 ZNF292

1.26e-043771029int:CENPA
InteractionBTG3 interactions

MYCBP2 CCDC13 ATXN1 PAK1 AFF4

1.41e-04981025int:BTG3
InteractionYWHAQ interactions

CYLD ABI1 SASH1 MYCBP2 KIF26B SIPA1L3 PSD3 CEP192 N4BP3 SHTN1 ATXN1 TET1 ZNF638 NAV1 KMT2A ULK4

1.51e-04111810216int:YWHAQ
InteractionODF2 interactions

CCDC14 CYLD SIPA1L3 CEP192 TNRC6C CEP72

1.53e-041581026int:ODF2
InteractionFXR1 interactions

SMG1 ABI1 MYCBP2 N4BP3 THOC2 TASOR2 ZC3H7A ATXN1 CEP72 GLE1 PAK1 TP53BP1

1.64e-0467910212int:FXR1
InteractionYWHAE interactions

CYLD ABI1 SASH1 MYCBP2 KIF26B SIPA1L3 PSD3 NCBP1 SRCIN1 N4BP3 SHTN1 LPIN1 ATXN1 TET1 ZNF638 NAV1 KMT2A

1.80e-04125610217int:YWHAE
InteractionRNF41 interactions

CYLD SIPA1L3 CEP192 N4BP3 SHTN1 NAV1

1.87e-041641026int:RNF41
InteractionETV6 interactions

CYLD CEP192 TNRC6C TLE3 TP53BP1

1.95e-041051025int:ETV6
InteractionSFN interactions

CYLD SASH1 MYCBP2 KIF26B SIPA1L3 CEP192 N4BP3 SHTN1 ATXN1 ZNF638 NAV1 KMT2A

1.96e-0469210212int:SFN
InteractionDUSP16 interactions

CCDC14 TRO CEP192 DSN1 TASOR2 GLE1 NAV1

2.04e-042371027int:DUSP16
InteractionKDM1B interactions

CYLD CEP192 CCNT1 KDM1B

2.13e-04581024int:KDM1B
InteractionRPL13 interactions

USP36 CYLD ZNF845 TRO ZNF813 SRPK1 NKRF GLE1 ZNF638 KMT2A RBM34 RAVER1

2.18e-0470010212int:RPL13
InteractionSMG7 interactions

SMG1 MAML1 TNRC6C NKRF ZC3H7A TLE3 TET1 RAVER1

2.18e-043191028int:SMG7
InteractionEGR2 interactions

BCORL1 MAML1 ATXN1 TLE3 TET1 KMT2A

2.35e-041711026int:EGR2
Cytoband19q13.41

ZNF321P ZNF600 ZNF611 ZNF808 ZNF701

1.05e-0678105519q13.41
Cytoband7q31.3

PTPRZ1 CADPS2

5.34e-041510527q31.3
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF845 ZNF321P SIPA1L3 ZNF813 ZNF8 ZNF600 ZNF611 ZNF808 ZNF701

1.69e-0311921059chr19q13
Cytoband16p12.3

SMG1 DCUN1D3

2.77e-0334105216p12.3
Cytoband3p22.1

CCDC13 ULK4

3.82e-034010523p22.1
CytobandEnsembl 112 genes in cytogenetic band chr7q31

ASB15 PTPRZ1 CADPS2

4.15e-031401053chr7q31
GeneFamilyAF4/FMR2 family|Super elongation complex

AFF3 AFF4

8.32e-0546821145
GeneFamilyAF4/FMR2 family|Super elongation complex

AFF3 AFF4

4.93e-0496821280
GeneFamilyZinc fingers CXXC-type

TET1 KMT2A

8.98e-0412682136
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF845 ZNF391 ZNF813 ZNF8 ZNF600 ZNF611 ZNF808 ZNF701 ZNF292

1.41e-0371868928
GeneFamilyAnkyrin repeat domain containing

ANKRD31 ANK2 BCORL1 ASB15 ANKRD33B

2.16e-03242685403
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

CYLD SYCP2L FRMPD4 ANK2 MYCBP2 BIVM AFF3 NBEA SRCIN1 TNRC6C SHTN1 PRDM2 LPIN1 GPR158 NAV1 CSMD1

6.44e-06110610316M39071
CoexpressionGSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN

SMG1 MYCBP2 MARCKSL1 IQCC CD68 KMT2A AFF4

1.00e-051891037M3112
CoexpressionGSE21670_UNTREATED_VS_TGFB_TREATED_CD4_TCELL_DN

SIPA1L3 BCORL1 NBEA KMT2A CADPS2 ANKRD33B FGD3

1.40e-051991037M7472
CoexpressionGSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN

CCDC14 WDR64 SASH1 PSD3 MARCKSL1 TET1 TP53BP1

1.45e-052001037M304
CoexpressionGABRIELY_MIR21_TARGETS

CCDC14 SASH1 MYCBP2 NBEA THOC2 LPIN1 TET1 ZNF292

1.91e-052891038M2196
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

ASXL1 ABI1 SASH1 MYCBP2 PSD3 THOC2 ADCY9 JARID2 ATXN1 MICAL2 ZNF638 TP53BP1 ZNF292

3.12e-0585610313M4500
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

CYLD SMG1 ZNF845 TMEM199 CEP192 SHTN1 DSN1 NKRF TASOR2 ZNF600 CEP72 TET1 PAK1 HFM1 KDM1B PHYHIPL CCDC191

3.54e-0782010217gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#4_top-relative-expression-ranked_500

ZNF845 TMEM199 CEP192 SHTN1 TET1 CCDC191

9.28e-061011026gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k4_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000

CCDC14 SYCP2L ZNF845 BCORL1 CEP192 SHTN1 NKRF JARID2 CCNT1 PTPRZ1 TET1 PAK1 ZNF638 NAV1 PHYHIPL RAVER1

2.03e-0599410216Facebase_RNAseq_e8.5_Floor Plate_1000
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_500

ZNF845 TMEM199 CEP192 SHTN1 NKRF ZNF600 TET1 PAK1 HFM1 CCDC191

2.60e-0540610210gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_500
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000

ZNF845 TMEM199 NCBP1 CEP192 TNRC6C SHTN1 DSN1 NKRF TASOR2 ZNF600 TET1 PAK1 HFM1 CCDC191

3.26e-0581010214gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#1

BCORL1 CEP192 NKRF PTPRZ1 TET1 PAK1 ZNF638 PHYHIPL

3.59e-052591028Facebase_RNAseq_e8.5_Floor Plate_1000_K1
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000

CCDC14 ZNF845 TMEM199 ABCF2 CEP192 SHTN1 NKRF TASOR2 JARID2 ZNF600 TET1 PAK1 HFM1 CCDC191

3.83e-0582210214gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlasfacebase_RNAseq_e8.5_FloorPlate_2500_K3

CCDC14 USP36 TIGAR ZNF845 ZNF813 SRPK1 NCBP1 CEP192 NKRF JARID2 IQCC BSG PTPRZ1 TET1 PAK1 NAV1 CADPS2 PHYHIPL

8.59e-05137110218facebase_RNAseq_e8.5_FloorPlate_2500_K3
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500

CYLD ZNF845 NKRF TASOR2 ZNF600 PAK1 HFM1 PHYHIPL CCDC191

1.00e-043851029gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000

CCDC14 ZNF845 TMEM199 CEP192 SHTN1 NKRF JARID2 ZNF600 TET1 PAK1 HFM1 PHYHIPL CCDC191

1.11e-0479510213gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_500

ZNF845 TMEM199 CEP192 SHTN1 ZNF600 TET1 PAK1 HFM1 CCDC191

1.24e-043961029gudmap_dev gonad_e13.5_M_GermCell_Oct_500
CoexpressionAtlasdev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_200

NYAP2 ANK2 PTPRZ1 PHYHIPL

1.42e-04551024gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k1_200
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000

TMEM199 NCBP1 CEP192 TNRC6C DSN1 NKRF PAK1 CCDC191

2.05e-043331028gudmap_dev gonad_e13.5_M_GermCell_Oct_k1_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

SYCP2L ZNF845 ANK2 KIF26B SHTN1 NKRF ZC3H7A ATXN1 PTPRZ1 PAK1 CD68 KDM1B POLQ PHYHIPL

2.53e-0498310214Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 ANK2 SASH1 SHTN1 PAK1 NAV1 CD68 MARCKS

5.89e-0916910383f8aa6d2f9aa060ae1a0ea3eb47e794099fc2c2c
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 ANK2 SASH1 SHTN1 PAK1 NAV1 CD68 MARCKS

5.89e-09169103826de495c7562e0740689d0f78e803698e3e793db
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 ANK2 SASH1 SHTN1 PAK1 NAV1 CD68 MARCKS

6.17e-091701038670027daec5a10dfa12246f1497b58db21d32a22
ToppCellmLN-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

PSD3 MARCKSL1 ZC3H7A ATXN1 NAV1 SNX11 ANKRD33B MARCKS

2.20e-0820010383813fa1ee1462ba83fd8b6253070f46f0b063084
ToppCelldroplet-Spleen-nan-24m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 SASH1 SHTN1 PAK1 NAV1 CD68 MARCKS

1.48e-07171103735acc5c3e36bc605603c0d45375f2cf3c3e9d4cd
ToppCelldroplet-Spleen-SPLEEN-30m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 SASH1 SHTN1 PAK1 NAV1 CD68 MARCKS

1.94e-0717810376c1b5087581ca8cea976d89ea6f34088c8fc3668
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD4 AFF3 NBEA GPR158 MICAL2 PAK1 CSMD1

3.99e-0719810374ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCelldroplet-Spleen-nan-3m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 SHTN1 PAK1 NAV1 CD68 MARCKS

2.45e-061661036c1f18de4a1a2b6cdc703e6d29d136e1134fcbdf3
ToppCelldroplet-Spleen-nan-3m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 SHTN1 PAK1 NAV1 CD68 MARCKS

2.45e-06166103694c30d6ca179d0cb02a5ed0093c5a2871e17ae50
ToppCell356C-Myeloid-Dendritic-cDC_activated|356C / Donor, Lineage, Cell class and subclass (all cells)

PSD3 MARCKSL1 NAV1 SNX11 ANKRD33B MARCKS

2.54e-06167103643a9375fdbafd7450c553e4620e21537e08639dd
ToppCellILEUM-non-inflamed-(3)_mature_DC|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PSD3 MARCKSL1 BSG NAV1 ANKRD33B MARCKS

2.81e-06170103660151394460e6f27a42fab434e8b7b2adc78b128
ToppCelldroplet-Spleen-nan-18m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 SHTN1 PAK1 NAV1 CD68 MARCKS

2.91e-0617110364a2e6ea9674bf23e8012ef0bb2bf19ce1f55fcd5
ToppCelldroplet-Spleen-nan-3m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 SHTN1 PAK1 NAV1 CD68 MARCKS

2.91e-0617110365b74df72e36ad04dfb25c72f1ca8efe043f6cda6
ToppCelldroplet-Spleen-nan-21m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 SHTN1 PAK1 NAV1 CD68 MARCKS

3.01e-0617210364fe5b91e4871bc6c5be57eb5b8bb04815b2fb80d
ToppCelldroplet-Spleen-nan-18m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 SHTN1 PAK1 NAV1 CD68 MARCKS

3.01e-061721036850e4c9e9003807c19695be4b13121b0808a9389
ToppCelldroplet-Spleen-nan-18m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 SHTN1 PAK1 NAV1 CD68 MARCKS

3.01e-061721036018d8160cfcb7882475620dc678f48a69a0f643e
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYLD MYCBP2 AFF3 PRDM2 ANKRD33B MARCKS

4.58e-061851036e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PSD3 MARCKSL1 JARID2 NAV1 ANKRD33B MARCKS

4.58e-06185103648de4d9fad55077732bf64eca4919103ecbc1512
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ASXL1 JARID2 ZNF638 MARCKS AFF4 ZNF292

5.66e-061921036916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellILEUM-inflamed-(3)_MNP-(3)_mature_DC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PSD3 MARCKSL1 NAV1 SNX11 ANKRD33B MARCKS

5.83e-061931036d9be4d1de863fffc2240d6fd1a2f8dfb2d2bc916
ToppCellnormal_Lymph_Node-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

PSD3 MARCKSL1 NAV1 SNX11 ANKRD33B MARCKS

5.83e-061931036024d30eb143d8278c0851c3a6c9426226fa3b480
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

ASXL1 JARID2 ZNF638 MARCKS AFF4 ZNF292

5.83e-061931036e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD4 AFF3 NBEA GPR158 MICAL2 CSMD1

6.37e-061961036676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

CYLD SMG1 MARCKSL1 KMT2A AFF4 ZNF292

6.37e-0619610367bced0cc2112697593c478fa291b8ed3941fb811
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 TNRC6C LPIN1 CCNT1 ZNF600 ZNF292

6.56e-061971036e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD4 AFF3 NBEA GPR158 MICAL2 CSMD1

6.75e-0619810366d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD4 AFF3 NBEA MICAL2 PAK1 CSMD1

6.75e-0619810368ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SASH1 SHTN1 PAK1 CD68 KDM1B MARCKS

6.95e-06199103618b6087863fda22e3e2a2167e7daeb347df1d95b
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

FRMPD4 MYCBP2 AFF3 NBEA MICAL2 CSMD1

7.15e-06200103648d801219bc771d6c7e151dc88ca4c179988de85
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 MYCBP2 PRDM2 KMT2A AFF4 ZNF292

7.15e-06200103612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

SYCP2L TASOR2 JARID2 TLE3 HFM1

2.51e-051491035768877bade04ca0321593b8470b5011ad8270431
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|343B / Donor, Lineage, Cell class and subclass (all cells)

CEP72 PAK1 CD68 ANKRD33B MCEMP1

3.03e-05155103584221a285277292f7225eb69508c887541abeed1
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Pre-B|bone_marrow / Manually curated celltypes from each tissue

AFF3 CLEC20A NAV1 CCDC191 MARCKS

3.75e-051621035e088e66aabc307dde5d2b9aa295c34ef68155b1a
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MARCKSL1 N4BP3 PPL CCDC13 CCDC191

3.97e-0516410351aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCelldroplet-Spleen-nan-21m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHTN1 PAK1 NAV1 CD68 MCEMP1

4.09e-051651035fbd84f211ad645c91b9f45a0815391606f3206ac
ToppCelldroplet-Spleen-nan-21m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHTN1 PAK1 NAV1 CD68 MCEMP1

4.09e-0516510356fbdfacb49e627712ac999d40ae22dcb390edd3e
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 SRCIN1 SHTN1 CD68 MARCKS

4.21e-05166103591eeb48680dd07ae4115afacdc0a8f6fa18885e5
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

N4BP3 NKRF HFM1 ANKRD33B MARCKS

4.58e-05169103541ad349806b279fbe1374b7e3cc7f146a11adb44
ToppCell356C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SYCP2L TIGAR PTDSS1 ZNF808 CCDC191

4.58e-0516910350425d2580ed325178f522c0093ff4623de6ce7a8
ToppCell356C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SYCP2L TIGAR PTDSS1 ZNF808 CCDC191

4.58e-051691035fec669968a77060bd77ee8695034e35a642c984f
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

N4BP3 NKRF HFM1 ANKRD33B MARCKS

4.58e-05169103542782c61592742190ab0cba8a94f8bdf9c278f90
ToppCell356C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

PSD3 MARCKSL1 SNX11 ANKRD33B MARCKS

4.71e-051701035513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SIPA1L3 AFF3 N4BP3 ANKRD33B MARCKS

4.85e-051711035b6ee3a6bc436df5e9129b8e0bed9fa3078a4ff23
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC|lymph-node_spleen / Manually curated celltypes from each tissue

SEMG1 PSD3 MARCKSL1 NAV1 ANKRD33B

4.98e-0517210351b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCell5'-Adult-Distal_Rectal-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BCORL1 NBEA ADCY9 LPIN1 ANKRD33B

5.12e-05173103562abaaaf48cabd1423f17fb27c33b75ea88867f4
ToppCell5'-Adult-Distal_Rectal-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BCORL1 NBEA ADCY9 LPIN1 ANKRD33B

5.12e-05173103509cd878c33534bd476d6a4880f5582076189da8c
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIGAR SASH1 N4BP3 ZNF8 HFM1

5.56e-0517610357292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIGAR SASH1 N4BP3 ZNF8 HFM1

5.56e-05176103588ca2f83d8301633232735f39b0683efe49d0b86
ToppCellfacs-Marrow-KLS-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHTN1 PAK1 NAV1 CD68 MARCKS

5.86e-0517810356bad4439a1692332f70135ff446a1048fa4c399d
ToppCellfacs-Marrow-KLS-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHTN1 PAK1 NAV1 CD68 MARCKS

5.86e-0517810353f6feb4ed7779cf5684f52939350b41d7718c3c6
ToppCellrenal_papilla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

SASH1 KIF26B PSD3 PPL NAV1

6.18e-05180103549829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Erythrophagocytic_macrophages|bone_marrow / Manually curated celltypes from each tissue

PSD3 SHTN1 NAV1 CD68 MARCKS

6.18e-051801035daf69a548ed7c6f285a6adcff00f99aa22f9d6a5
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYLD AFF3 PRDM2 LPIN1 ANKRD33B

6.34e-051811035d66838fca0429cad2079cd8d92a5cd33eb0d3522
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYCBP2 SIPA1L3 AFF3 PRDM2 ANKRD33B

6.34e-0518110358d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCellnucseq-Immune-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYCBP2 SIPA1L3 AFF3 PRDM2 ANKRD33B

6.86e-051841035911658e7bb499c1bbc8419eec8ff88729bc39a75
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

KIF26B AFF3 MARCKSL1 PAK1 MARCKS

6.86e-0518410350a26bcc6610f756939e32a4d6dfeebcbf3a1db86
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYCBP2 SIPA1L3 AFF3 PRDM2 ANKRD33B

6.86e-051841035942b58ae7172bb5f97e55b032db9329d161854af
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_2|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KIF26B AFF3 MARCKSL1 PAK1 MARCKS

7.04e-051851035fec16a5e527fdef32d25957451b6e8ee9796cafd
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

CCDC14 MYCBP2 CCNT1 POLQ ZNF292

7.22e-0518610358571956890fc9894d766ba294a28e376b4aba428
ToppCellnormal_Lung-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

MARCKSL1 GPR158 NAV1 ANKRD33B MARCKS

7.22e-05186103500ad1239b952119b3fd2e6af8f034cba3488f9c1
ToppCellControl-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

SIPA1L3 AFF3 PRDM2 ANKRD33B MARCKS

7.40e-0518710354e64be635f445276e71f2937f33f041c3a4204ab
ToppCell390C-Myeloid-Dendritic-cDC_activated|390C / Donor, Lineage, Cell class and subclass (all cells)

PSD3 MARCKSL1 NAV1 ANKRD33B MARCKS

7.40e-05187103560c2576f31a60f819deb9ec500d1f714b469df4e
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SMG1 PRDM2 TASOR2 KMT2A TP53BP1

7.59e-051881035ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellCOPD-Myeloid-DC_Mature|COPD / Disease state, Lineage and Cell class

SIPA1L3 MARCKSL1 NAV1 ANKRD33B MARCKS

7.59e-051881035de93ccb53edb8599da9e312db0e3af604c21f673
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SASH1 SIPA1L3 PPL PHYHIPL ANKRD33B

7.59e-05188103563a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

NYAP2 FRMPD4 MYCBP2 GPR158 KMT2A

7.98e-051901035416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYCBP2 AFF3 PRDM2 CLEC20A CCDC191

7.98e-051901035a7498fe55b7810c482291db782dc5282675d246a
ToppCellnormal_Lymph_Node-Myeloid_cells-Activated_DCs|normal_Lymph_Node / Location, Cell class and cell subclass

PSD3 MARCKSL1 NAV1 ANKRD33B MARCKS

7.98e-05190103515978ddd37b521343f88b62dad1643077fc22b2b
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_memory-0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AFF3 N4BP3 PRDM2 ANKRD33B MARCKS

7.98e-05190103595b9334573eefb132daaa9371377ad60232006ae
ToppCell10x5'-GI_small-bowel-Myeloid_Dendritic-migDC|GI_small-bowel / Manually curated celltypes from each tissue

PSD3 MARCKSL1 PAK1 NAV1 MARCKS

7.98e-051901035e9b2c201d07f0cb87fa60005251c9e1663e246ed
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

SIPA1L3 AFF3 PRDM2 ANKRD33B MARCKS

7.98e-0519010351e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCellControl-Myeloid-cDC2|World / Disease state, Lineage and Cell class

SIPA1L3 AFF3 JARID2 PAK1 CSMD1

8.18e-05191103511dfd8f38beb294f42710cfbd355cb089e1023c0
ToppCellFetal_29-31_weeks-Immune-B_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SIPA1L3 AFF3 PRDM2 CCDC191 ANKRD33B

8.18e-05191103584452125d1b5b76974e3f9126f611eff16d45c25
ToppCellCOPD-Myeloid-cDC2|COPD / Disease state, Lineage and Cell class

SIPA1L3 AFF3 JARID2 PAK1 CSMD1

8.18e-0519110352af6e4a6bd1f2193ece2131c3b7d976dd23a6966
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_memory|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AFF3 N4BP3 PRDM2 ANKRD33B MARCKS

8.18e-05191103522134a2c1a92208bc1629a620ce73a56502613c2
ToppCellCOPD-Myeloid-cDC2|World / Disease state, Lineage and Cell class

SIPA1L3 AFF3 JARID2 PAK1 CSMD1

8.18e-0519110354e4887175200a57e1b041f2f131e3df774df3509
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SIPA1L3 AFF3 PRDM2 CCDC191 MARCKS

8.18e-0519110355a9a592875fbd0b1429b48db29a760fdc9c2c856
ToppCellCOPD-Myeloid-cDC2|Myeloid / Disease state, Lineage and Cell class

SIPA1L3 AFF3 JARID2 PAK1 CSMD1

8.38e-051921035984cdc2f1d93e164bc946d63f58dacb629f82eb7
ToppCellCOPD-Myeloid-DC_Mature|Myeloid / Disease state, Lineage and Cell class

SIPA1L3 MARCKSL1 NAV1 ANKRD33B MARCKS

8.38e-051921035baebd462f464e7d0e462d07a74bb5d685a9fc3b6
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_memory-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AFF3 N4BP3 PRDM2 ANKRD33B MARCKS

8.38e-051921035debd471f61cf3606b8e9c246add0be5df601af7f
ToppCellCOVID-19_Mild-Lymphoid_B-B_memory|COVID-19_Mild / Disease group, lineage and cell class

AFF3 N4BP3 PRDM2 ANKRD33B MARCKS

8.38e-051921035d27db7669de95bddbea8ccb83e6f10ae7240b1ab
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_memory|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AFF3 N4BP3 PRDM2 ANKRD33B MARCKS

8.38e-051921035314f74dd3c6d94839eed05b9a1a398217ef78029
ToppCell367C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

PSD3 MARCKSL1 ZC3H7A ANKRD33B MARCKS

8.38e-051921035e44e37e5aeba8628556020d05e1606b28e2faa4f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ASXL1 AFF3 N4BP3 PRDM2 ANKRD33B

8.59e-051931035bbea475d2c4c7b29674ff302529f8f83dd666dcb
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

AFF3 THOC2 PRDM2 CCDC191 MARCKS

8.59e-05193103508696a99309f5b088692ddac8cca35413b5e810d
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-9|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SIPA1L3 AFF3 PRDM2 CLEC20A CCDC191

8.59e-051931035d5d188a314da1b4c8390276d88173c09dd7ce4bf
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

CLIP2 MYCBP2 PRDM2 ANKRD33B MARCKS

8.59e-0519310357ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCellILEUM-inflamed-(3)_mature_DC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

MARCKSL1 BSG NAV1 ANKRD33B MARCKS

8.80e-051941035369bbf4e8e2d674e5a51a614b52b97d05d3ab9c7
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MARCKSL1 JARID2 TLE3 MARCKS MCEMP1

8.80e-0519410353ef9e88e66f2f2ae95dcc834ea605c40c60783fc
ToppCell3'_v3-Lung-Myeloid_Dendritic|Lung / Manually curated celltypes from each tissue

AFF3 MARCKSL1 PAK1 NAV1 ANKRD33B

9.01e-051951035b748cb15846345363e8c2ee5936bb42bba3ba9a7
ToppCellBAL-Mild-Myeloid-cDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

MARCKSL1 PAK1 NAV1 ANKRD33B MARCKS

9.01e-0519510356ba23e19801305e071b0e4aaf1ee6f53f3b027d3
ToppCellBAL-Mild-Myeloid-cDC-cDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MARCKSL1 PAK1 NAV1 ANKRD33B MARCKS

9.01e-05195103566e5fd9f3208a06d617c5e994822bf57dceae7e2
ToppCellBAL-Mild-Myeloid-cDC-cDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

MARCKSL1 PAK1 NAV1 ANKRD33B MARCKS

9.01e-0519510357209babdff96c93cd52cfe5d5cfd7e3c0274d8dd
ToppCellBAL-Mild-Myeloid-cDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MARCKSL1 PAK1 NAV1 ANKRD33B MARCKS

9.01e-0519510359e5cf33b5dd455efa464a63d7116786c0786aefd
ToppCellMild_COVID-19-Myeloid-cDC|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

MARCKSL1 PAK1 NAV1 ANKRD33B MARCKS

9.01e-05195103524149bb6933135b1a0a5c7f505914942b3782c3a
ToppCell390C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PSD3 MARCKSL1 NAV1 ANKRD33B MARCKS

9.01e-051951035ecf7d9856a5b507ec17c325c9a772dc5a184bc8e
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD4 MICAL2 PAK1 CSMD1 CADPS2

9.01e-0519510352e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

SIPA1L3 AFF3 ADCY9 ATXN1 CADPS2

9.23e-051961035ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellLung_Parenchyma-Control-Lymphocyte-B-B_cell-B_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

AFF3 MARCKSL1 N4BP3 PRDM2 ANKRD33B

9.23e-051961035279f113916dcb398111d787ae06bcf20ff8febd2
ToppCellParenchyma_Control_(B.)-Immune-TX-B_cells|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

AFF3 MARCKSL1 N4BP3 PRDM2 ANKRD33B

9.23e-051961035a2759691606b03de9d67e8d38487915cd4e7d448
Diseaseinsulin resistance

USP36 NYAP2 ANK2 CSMD1

4.53e-0559984EFO_0002614
Diseaseblood manganese measurement

ADCY9 TLE3 CSMD1

9.81e-0527983EFO_0007581
Diseasefree cholesterol to total lipids in small VLDL percentage

ANKRD31 NYAP2 PSD3 TP53BP1

1.16e-0475984EFO_0022287
Diseasefree cholesterol:total lipids ratio, intermediate density lipoprotein measurement

ANKRD31 NYAP2 PSD3 TP53BP1

1.97e-0486984EFO_0008595, EFO_0020945
DiseaseNeurodevelopmental Disorders

ANK2 PAK1 KMT2A ZNF292

2.66e-0493984C1535926
Diseasemyelofibrosis (is_implicated_in)

ASXL1 KMT2A

3.02e-048982DOID:4971 (is_implicated_in)
Diseasefree cholesterol to total lipids in very small VLDL percentage

NYAP2 PSD3 TP53BP1

3.98e-0443983EFO_0022290
Diseaseejection fraction measurement

ATXN1 GPR158 CADPS2

3.98e-0443983EFO_0005527
Diseaseglucagon-like peptide-1 measurement

ULK4 CSMD1

4.83e-0410982EFO_0008465
DiseaseAmyotrophic Lateral Sclerosis, Sporadic

BSG TLE3 CD68

5.51e-0448983C1862941
DiseaseAmyotrophic Lateral Sclerosis, Familial

BSG TLE3 CD68

5.51e-0448983C4551993
Diseasemammographic density measurement

AFF3 NBEA ATXN1

6.22e-0450983EFO_0005941
DiseaseAMYOTROPHIC LATERAL SCLEROSIS 1

BSG TLE3 CD68

6.22e-0450983C1862939
Diseasepolyunsaturated fatty acids to monounsaturated fatty acids ratio

NYAP2 PSD3 TP53BP1

6.59e-0451983EFO_0022302
DiseaseSchizophrenia

ST6GALNAC1 PSD3 JARID2 PTPRZ1 TET1 NAV1 KMT2A ULK4 CSMD1 CADPS2

7.13e-048839810C0036341
Diseasemonoclonal gammopathy

ULK4 HFM1 CSMD1

7.38e-0453983EFO_0000203
Diseaseresponse to paliperidone, schizophrenia symptom severity measurement

NYAP2 AFF3 PSD3 ZNF611 CSMD1

7.85e-04216985EFO_0007925, EFO_0007927
Diseaseillegal drug consumption

WDR64 CSMD1

8.32e-0413982EFO_0005431
Diseasetriglycerides in LDL measurement

NYAP2 PSD3 TP53BP1

8.67e-0456983EFO_0022320
Diseasefree cholesterol to total lipids in medium VLDL percentage

ANKRD31 NYAP2 TP53BP1

9.13e-0457983EFO_0022284
Diseasetriglycerides to total lipids in small LDL percentage

NYAP2 PSD3 TP53BP1

1.01e-0359983EFO_0022337
Diseasecholesteryl esters to total lipids in large HDL percentage

NYAP2 PSD3 TP53BP1

1.01e-0359983EFO_0022248
Diseasecholesterol in chylomicrons and extremely large VLDL measurement

NYAP2 PSD3 TP53BP1

1.06e-0360983EFO_0021898
Diseasefree cholesterol in very large VLDL measurement

ANKRD31 NYAP2 TP53BP1

1.11e-0361983EFO_0022274
Diseasetriglycerides in medium LDL measurement

NYAP2 PSD3 TP53BP1

1.17e-0362983EFO_0022322
DiseaseVertigo

SYCP2L TIGAR ABI1 PRDM2

1.21e-03139984HP_0002321
Diseasetriglycerides to total lipids in medium VLDL percentage

ANKRD31 NYAP2 TP53BP1

1.22e-0363983EFO_0022335
Diseasecholesterol to total lipids in medium VLDL percentage

ANKRD31 NYAP2 TP53BP1

1.22e-0363983EFO_0022239
Diseasefree cholesterol to total lipids in medium LDL percentage

NYAP2 PSD3 TP53BP1

1.22e-0363983EFO_0022283
Diseasephospholipids in chylomicrons and extremely large VLDL measurement

NYAP2 PSD3 TP53BP1

1.22e-0363983EFO_0022292
Diseasetriglycerides in small LDL measurement

NYAP2 PSD3 TP53BP1

1.34e-0365983EFO_0022323
Diseasetriacylglycerol 48:1 measurement

NYAP2 CSMD1

1.44e-0317982EFO_0010404
Diseaseemphysema imaging measurement

MROH9 MYCBP2 ZNF600 CSMD1

1.45e-03146984EFO_0007626
Diseasetriglycerides in very small VLDL measurement

NYAP2 PSD3 TP53BP1

1.52e-0368983EFO_0022144
Diseasefree cholesterol in large VLDL measurement

ANKRD31 NYAP2 TP53BP1

1.52e-0368983EFO_0022265
Diseasereaction time measurement

CEP192 TNRC6C JARID2 CEP72 PTPRZ1 TET1 ZNF638 CSMD1

1.59e-03658988EFO_0008393
Diseasetriglycerides to total lipids in very small VLDL percentage

NYAP2 PSD3 TP53BP1

1.59e-0369983EFO_0022341
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

ANKRD31 NYAP2 PSD3 TP53BP1

1.60e-03150984EFO_0004611, EFO_0020947
Diseaseinferior parietal cortex volume measurement

TBC1D15 SHTN1

1.80e-0319982EFO_0010307
Diseasefree cholesterol to total lipids in large LDL percentage

NYAP2 PSD3 TP53BP1

1.94e-0374983EFO_0022280
DiseaseAmphetamine-Related Disorders

PSD3 PRDM2 CSMD1

2.02e-0375983C0236733
DiseaseAmphetamine Abuse

PSD3 PRDM2 CSMD1

2.02e-0375983C0236807
DiseaseAmphetamine Addiction

PSD3 PRDM2 CSMD1

2.02e-0375983C0236804
Diseasesex interaction measurement, cerebral amyloid angiopathy

SRCIN1 ADCY9

2.20e-0321982EFO_0006790, EFO_0008343
Diseasemonounsaturated fatty acids; 16:1, 18:1 measurement

NYAP2 PSD3 TP53BP1

2.26e-0378983EFO_0022187
DiseaseQRS duration, response to sulfonylurea

ZNF638 CSMD1

2.64e-0323982EFO_0005055, EFO_0007922
Diseasesensory peripheral neuropathy, remission

KMT2A CSMD1

2.64e-0323982EFO_0009785, MONDO_0002321
Diseasenicotine dependence symptom count

SYCP2L CLIP2 MYCBP2 NBEA CSMD1

2.65e-03285985EFO_0009262
DiseaseRheumatoid Arthritis

ABCC3 AFF3 TLE3 MARCKS

2.74e-03174984C0003873
Diseasepulmonary embolism

ZNF808 ZNF701

3.12e-0325982EFO_0003827
Diseaseheel bone mineral density, urate measurement

ANKRD31 AFF3 PSD3 MAML1

3.22e-03182984EFO_0004531, EFO_0009270

Protein segments in the cluster

PeptideGeneStartEntry
SQLVSSGHNNPKKGD

AFF3

336

P51826
GHGSAKLARQAQSKE

ABCF2

346

Q9UG63
PSKDGSHKNSVLSQG

CSMD1

326

Q96PZ7
KSPRGASDSGKEHNG

BCORL1

1161

Q5H9F3
KSGLTPIHSAADGQN

ASB15

306

Q8WXK1
LKAKHGNNQPARTGT

ABI1

156

Q8IZP0
NDSGNGEHKSERKSP

BIVM

11

Q86UB2
ASSKEGSPLHKQSSG

CLIP2

36

Q9UDT6
ATPNGTKGKDESQHT

GLE1

101

Q53GS7
SRHVKNGGSIPKSDQ

CGGBP1

131

Q9UFW8
GSHSALPGKKTALQA

CEP72

406

Q9P209
HSKLDKGPTGANGHN

CCNT1

636

O60563
SPSTLNDKSGLHLGK

ATXN1

406

P54253
QKKDGPSGNHLSRAS

CCDC74A

96

Q96AQ1
QKKDGPSGNHLSRAS

CCDC74B

96

Q96LY2
SSGRHTGPAKLTNGK

CCDC14

61

Q49A88
GSKNGDREPSNKSHS

DCUN1D3

16

Q8IWE4
GPLKANAENRKATGH

ASXL1

1376

Q8IXJ9
DKNSAGHKPSSNRES

AFF4

786

Q9UHB7
PARKGSTKDSGHLQI

ANKRD33B

441

A6NCL7
KQSHLSKAIGSSPLG

RAVER1

501

Q8IY67
GLNFTSKTAEGHPKS

RBM34

386

P42696
GTSNEPSHEGQKKQR

IQCC

416

Q4KMZ1
QTARHKASAAPGKNA

ABCC3

266

O15438
ANPKAEGLLQGKHST

PARP2

501

Q9UGN5
VHKSRKDHSSGNPGQ

PALM2

246

Q8IXS6
AFQSGQDPSKHKTGL

ANK2

1996

Q01484
AAQGTGNDCPHKKSA

CD68

16

P34810
STGLRKGNLHNVKDP

ANKRD31

706

Q8N7Z5
KPSGADALQSSGKHS

MAML1

166

Q92585
DGGQPHKRRKTSDAN

NCBP1

11

Q09161
KGKPHAQQPGRASAS

GPR158

41

Q5T848
ANKHGSKPSSLGVSN

KIF26B

261

Q2KJY2
KGPNGESSVIHDRKS

PPL

1701

O60437
KNGDPSGLAKHASDN

LPIN1

416

Q14693
QKADKDAGLAQHSGP

FGD3

141

Q5JSP0
PKLDNKERGHHGASS

NYAP2

556

Q9P242
PSANGLSQKHNDGKE

PTPRZ1

1506

P23471
DIGTNKPTNGKSHSL

MROH9

206

Q5TGP6
GTTASKKPGNRECNH

HFM1

1131

A2PYH4
NGHVKSNGDLSPKGE

MARCKSL1

31

P49006
AGSKDAGTLNHGSKP

PAK1

26

Q13153
HSKFDKDGQPLSGNR

ERVK-5

596

Q9HDB9
AATGNASPGKLEHSK

KDM1B

241

Q8NB78
TATQETGPENKGKHN

FRMPD4

531

Q14CM0
KNHDLSPGSRNGFKD

POLQ

1781

O75417
SLSAPGNKQHKTLGA

CCDC191

511

Q8NCU4
GLSLLHAGEPNSKNS

CCDC13

56

Q8IYE1
GSSPKKGGNCDLSHQ

DSN1

56

Q9H410
GSAPLKSSGQHQNDK

BSG

361

P35613
DEHKNSTKASGGPNP

ADCY9

656

O60503
TQKLNPKGGTLHADA

CADPS2

601

Q86UW7
SSPSKANGQENGHVK

MARCKS

26

P29966
KNQDHAKGGHSRPTS

MCEMP1

46

Q8IX19
KNSDLKNTSPEHGGR

CEP192

961

Q8TEP8
GNSSKQKIPADGVHR

KMT2A

1386

Q03164
VGDKGSSSHNKPKAT

CYLD

326

Q9NQC7
RNGSKEGNHHSTQPK

FAM104B

11

Q5XKR9
LRKTNSNKDGDQHSP

MICAL2

1576

O94851
KGGHSSPASSDKNSN

PRDM2

1496

Q13029
KSTPGRQAHGKADSA

JARID2

506

Q92833
KSEHSLFQAKGSPAG

NAV1

141

Q8NEY1
KDNSGSHGSPISGKL

PHYHIPL

211

Q96FC7
RQSSSHLAKGDQPKS

SNX11

166

Q9Y5W9
DSSSVLGHLGDGKKN

TNRC6C

601

Q9HCJ0
PLGKNHSSKVNSDSG

TIGAR

171

Q9NQ88
PSKGQKRHLSTCDGQ

NKRF

26

O15226
RDRGNKSSHGSSKPQ

NBEA

1491

Q8NFP9
NAGRNSASPKHSLNG

SMG1

1151

Q96Q15
KGGKAHRGTQNPSQD

SEMG1

131

P04279
AKEGSGFTKQSHQSP

PPP1R32

201

Q7Z5V6
GAKGDSHNGQPAKDS

SIPA1L3

256

O60292
KTKARAGAEQHSAGA

SIPA1L3

856

O60292
NKHPSRQDAAGKDSP

SIPA1L3

1241

O60292
QPKAHTTGDRGKEAN

ST6GALNAC1

91

Q9NSC7
SHPSGSGAKKEKATQ

SHTN1

381

A0MZ66
GSASKGKQQTSEPVH

MYCBP2

1391

O75592
QEHNGPLDNKGKSTA

SRPK1

461

Q96SB4
RAKGAGGQHVNKTDS

MTRF1

306

O75570
LAGSKQATLGAKPDH

TET1

331

Q8NFU7
SKEKTSAQKSGHPFG

CLEC20A

336

Q6ZU45
AGNKPIKDQLGSSFH

ZNF845

131

Q96IR2
RHAGNKPIKDQLGSS

ZNF321P

76

Q8N8H1
KHKGGDSSSGPQRLV

TMEM199

41

Q8N511
VKPSGRQIGKLSHSN

THOC2

561

Q8NI27
GHKVKGLTQDSNLPS

SPEM3

926

A0A1B0GUW6
AAQGQAGSPDKSKHG

SRCIN1

1111

Q9C0H9
RKSKHLNGDERSGSN

TRO

411

Q12816
PSSGSGHEKDQAKLL

SYCP2L

551

Q5T4T6
GPQNTRSSHLNKKGN

ZNF292

1611

O60281
DKDHPNTGNKKGSHS

ZNF292

2611

O60281
HAGNKPIKDQLGSSF

ZNF808

146

Q8N4W9
PLHKSNSEDSSVGKG

SASH1

131

O94885
SSDAEAQKLGKPSAH

TP53BP1

876

Q12888
HTNGDAPSHRNGKSK

TBC1D15

111

Q8TC07
AGNKPIKDQLGSSFH

ZNF813

131

Q6ZN06
TKDLGHNDKSSTPGL

TLE3

301

Q04726
KSVPGDGATKALNHS

ZC3H7A

186

Q8IWR0
QHPNSRKSSAGGAKA

ZNF8

516

P17098
HAGNKPIKDQLGSSF

ZNF611

146

Q8N823
SGDSLELRKNHKNGP

TASOR2

1231

Q5VWN6
HAGNKPIKNELGSSF

ZNF701

196

Q9NV72
RHAGNKPIKDQLGSS

ZNF600

76

Q6ZNG1
TKGSEDSPPKHAGNN

PTDSS1

436

P48651
KANGTHPKTISRIGS

PSD3

756

Q9NYI0
KPTSATKSDSNLGGH

ZNF638

621

Q14966
DHSKKNIGNGIISSP

USP36

451

Q9P275
RQAKGHKSGQPLGHS

ULK4

321

Q96C45
GPQSSKGSKQSIHDS

WDR64

736

B1ANS9
HGSPISRKNSKDNSD

ZNF391

81

Q9UJN7
SAKAENDKHLSVGPG

KIAA1522

21

Q9P206
NHLGGSLDRASQGPK

N4BP3

216

O15049