Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainPlakophilin/d_Catenin

PKP4 CTNND2

5.29e-047952IPR028435
DomainSialidases

RELN SORCS3

9.00e-049952IPR011040
DomainSpy1

SPDYE2 SPDYE2B

1.37e-0311952PF11357
DomainSpeedy

SPDYE2 SPDYE2B

1.37e-0311952IPR020984
DomainTyr_kinase_rcpt_2_CS

INSR ALK

1.37e-0311952IPR002011
DomainRECEPTOR_TYR_KIN_II

INSR ALK

1.63e-0312952PS00239
DomainIg-like_fold

EPHB6 INSR CAMTA2 LRRC4C PTPRF PXDNL BTN2A3P KIR2DL5A COL14A1 CD79A

3.13e-037069510IPR013783
DomainPkinase_Tyr

EPHB6 MATK INSR ALK

4.26e-03129954PF07714
DomainUDPGT

UGT1A6 UGT1A1

5.05e-0321952PF00201
DomainUDPGT

UGT1A6 UGT1A1

5.05e-0321952PS00375
DomainUDP_glucos_trans

UGT1A6 UGT1A1

5.05e-0321952IPR002213
DomainLRR_1

NLRP1 LRRC4C PXDNL LRRTM2 LRRC28

5.22e-03219955PF00560
DomainSer-Thr/Tyr_kinase_cat_dom

EPHB6 MATK INSR ALK

5.41e-03138954IPR001245
Pubmed

Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B.

KIR2DL5B KIR2DL5A

8.35e-062101212185535
Pubmed

Distinct functions of the two protein tyrosine phosphatase domains of LAR (leukocyte common antigen-related) on tyrosine dephosphorylation of insulin receptor.

INSR PTPRF

8.35e-062101211158333
Pubmed

Gene structure and promoter variation of expressed and nonexpressed variants of the KIR2DL5 gene.

KIR2DL5B KIR2DL5A

8.35e-062101211086080
Pubmed

Non tumoral hyperserotoninaemia responsive to octreotide due to dual polymorphism in UGT1A1 and UGT1A6.

UGT1A6 UGT1A1

8.35e-062101222450351
Pubmed

Combined UGT1A1 and UGT1A6 genotypes together with a stressful life event increase breast cancer risk.

UGT1A6 UGT1A1

8.35e-062101220686835
Pubmed

Association of KIR2DL5B gene with celiac disease supports the susceptibility locus on 19q13.4.

KIR2DL5B KIR2DL5A

8.35e-062101217215859
Pubmed

Characterizing the effects of common UDP glucuronosyltransferase (UGT) 1A6 and UGT1A1 polymorphisms on cis- and trans-resveratrol glucuronidation.

UGT1A6 UGT1A1

8.35e-062101219406951
Pubmed

Med1 deficiency alters the somatic hypermutation spectrum in murine B cells.

MED1 CD79A

8.35e-062101229293266
Pubmed

Identification and localization of a neurally expressed member of the plakoglobin/armadillo multigene family.

PKP4 CTNND2

8.35e-06210129342840
Pubmed

Insulin receptor protein-tyrosine phosphatases. Leukocyte common antigen-related phosphatase rapidly deactivates the insulin receptor kinase by preferential dephosphorylation of the receptor regulatory domain.

INSR PTPRF

8.35e-06210121321126
Pubmed

Combined polymorphisms in UDP-glucuronosyltransferases 1A1 and 1A6: implications for patients with Gilbert's syndrome.

UGT1A6 UGT1A1

8.35e-062101212480553
Pubmed

The development of UDP-glucuronosyltransferases 1A1 and 1A6 in the pediatric liver.

UGT1A6 UGT1A1

8.35e-062101221266593
Pubmed

Exome-Wide Association Study Identifies New Low-Frequency and Rare UGT1A1 Coding Variants and UGT1A6 Coding Variants Influencing Serum Bilirubin in Elderly Subjects: A Strobe Compliant Article.

UGT1A6 UGT1A1

8.35e-062101226039129
Pubmed

Cloning and substrate specificity of a human phenol UDP-glucuronosyltransferase expressed in COS-7 cells.

UGT1A6 UGT1A1

8.35e-06210123141926
Pubmed

Regulation of phosphoinositide 3-kinase by its intrinsic serine kinase activity in vivo.

INSR PIK3CA

2.50e-053101214729945
Pubmed

NLRP1, PTPN22 and PADI4 gene polymorphisms and rheumatoid arthritis in ACPA-positive Singaporean Chinese.

PADI4 NLRP1

2.50e-053101228653215
Pubmed

Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination.

MED1 CD79A

2.50e-053101226903242
Pubmed

PAPIN. A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071.

PKP4 CTNND2

2.50e-053101210896674
Pubmed

Protein tyrosine phosphatase regulation in fibroblasts from patients with an insulin receptor gene mutation.

INSR PTPRF

2.50e-053101218925540
Pubmed

Class I PI-3-Kinase Signaling Is Critical for Bone Formation Through Regulation of SMAD1 Activity in Osteoblasts.

PIK3CA SMAD1

2.50e-053101226896753
Pubmed

Linkage disequilibrium of UGT1A1 *6 and UGT1A1 *28 in relation to UGT1A6 and UGT1A7 polymorphisms.

UGT1A6 UGT1A1

2.50e-053101216969497
Pubmed

Functional polymorphisms of UDP-glucuronosyltransferases 1A1, 1A6 and 1A8 are not involved in chronic pancreatitis.

UGT1A6 UGT1A1

2.50e-053101215247627
Pubmed

Trans-induced cis interaction in the tripartite NGL-1, netrin-G1 and LAR adhesion complex promotes development of excitatory synapses.

LRRC4C PTPRF

2.50e-053101223986473
Pubmed

Frequent co-occurrence of the TATA box mutation associated with Gilbert's syndrome (UGT1A1*28) with other polymorphisms of the UDP-glucuronosyltransferase-1 locus (UGT1A6*2 and UGT1A7*3) in Caucasians and Egyptians.

UGT1A6 UGT1A1

2.50e-053101212732365
Pubmed

Phase II study of a triplet regimen of S-1 combined with irinotecan and oxaliplatin in patients with metastatic gastric cancer: clinical and pharmacogenetic results.

UGT1A6 UGT1A1

2.50e-053101220860988
Pubmed

UGT1A1, UGT1A6 and UGT1A7 genetic analysis: repercussion for irinotecan pharmacogenetics in the São Miguel Island Population (Azores, Portugal).

UGT1A6 UGT1A1

2.50e-053101219712005
Pubmed

p120-Catenin Downregulation and PIK3CA Mutations Cooperate to Induce Invasion through MMP1 in HNSCC.

PIK3CA MMP1

2.50e-053101228637905
Pubmed

Promoter variants of KIR2DL5 add to diversity and may impact gene expression.

KIR2DL5B KIR2DL5A

2.50e-053101218461314
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DNAJC13 COPA BTAF1 MED1 MYOF CNOT1

2.86e-05202101633005030
Pubmed

Alteration of the function of the UDP-glucuronosyltransferase 1A subfamily by cytochrome P450 3A4: different susceptibility for UGT isoforms and UGT1A1/7 variants.

UGT1A6 UGT1A1

4.99e-054101224255116
Pubmed

Coexistence of PIK3CA and other oncogene mutations in lung adenocarcinoma-rationale for comprehensive mutation profiling.

PIK3CA ALK

4.99e-054101222135231
Pubmed

Cloning of two human liver bilirubin UDP-glucuronosyltransferase cDNAs with expression in COS-1 cells.

UGT1A6 UGT1A1

4.99e-05410121898728
Pubmed

Urinary excretion of phenytoin metabolites, 5-(4'-hydroxyphenyl)-5-phenylhydantoin and its O-glucuronide in humans and analysis of genetic polymorphisms of UDP-glucuronosyltransferases.

UGT1A6 UGT1A1

4.99e-054101215855726
Pubmed

Killer-cell immunoglobulin-like receptors (KIR) in severe A (H1N1) 2009 influenza infections.

KIR2DL5B KIR2DL5A

4.99e-054101222652695
Pubmed

Chromosomal mapping of a human phenol UDP-glucuronosyltransferase, GNT1.

UGT1A6 UGT1A1

4.99e-05410122108603
Pubmed

Identification of defect in the genes for bilirubin UDP-glucuronosyl-transferase in a patient with Crigler-Najjar syndrome type II.

UGT1A6 UGT1A1

4.99e-05410128280139
Pubmed

PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells.

PKP4 CTNND2

4.99e-054101219706687
Pubmed

KIR2DL5, a novel killer-cell receptor with a D0-D2 configuration of Ig-like domains.

KIR2DL5B KIR2DL5A

4.99e-054101210820258
Pubmed

Mechanisms of inherited deficiencies of multiple UDP-glucuronosyltransferase isoforms in two patients with Crigler-Najjar syndrome, type I.

UGT1A6 UGT1A1

4.99e-05410121634050
Pubmed

TGFbeta modulates PTEN expression independently of SMAD signaling for growth proliferation in colon cancer cells.

PIK3CA SMAD1

4.99e-054101218769113
Pubmed

Coimmunoprecipitation of UDP-glucuronosyltransferase isoforms and cytochrome P450 3A4.

UGT1A6 UGT1A1

4.99e-054101215486048
Pubmed

CtIP is essential for early B cell proliferation and development in mice.

DCLRE1C CD79A

4.99e-054101231097467
Pubmed

Identification of an A-to-G missense mutation in exon 2 of the UGT1 gene complex that causes Crigler-Najjar syndrome type 2.

UGT1A6 UGT1A1

4.99e-05410128276413
Pubmed

RAS signalling through PI3-Kinase controls cell migration via modulation of Reelin expression.

RELN PIK3CA

4.99e-054101227071537
Pubmed

Gain of ALK gene copy number may predict lack of benefit from anti-EGFR treatment in patients with advanced colorectal cancer and RAS-RAF-PI3KCA wild-type status.

PIK3CA ALK

4.99e-054101224691006
Pubmed

Investigation of killer cell immunoglobulin-like receptor (KIR) gene diversity: KIR2DL2, KIR2DL5 and KIR2DS5.

KIR2DL5B KIR2DL5A

4.99e-054101218498296
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

COPA GART CDCP1 MYOF LRRTM2 ANKRD11 CNOT1

5.41e-05332101737433992
Pubmed

PI3Kα inactivation in leptin receptor cells increases leptin sensitivity but disrupts growth and reproduction.

INSR PIK3CA

8.30e-055101229212950
Pubmed

Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad.

ITGAV SMAD1

8.30e-055101218310319
Pubmed

Altered expressions and splicing profiles of Acin1 transcripts differentially modulate brown adipogenesis through an alternative splicing mechanism.

INSR MAP4K4

8.30e-055101232629174
Pubmed

Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta-catenin.

PKP4 CTNND2

8.30e-055101210037471
Pubmed

Chromosomal mapping of human armadillo genes belonging to the p120(ctn)/plakophilin subfamily.

PKP4 CTNND2

8.30e-05510129721216
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PITPNM2 TMEM144 DNAJC13 INSR PEPD DGKH BTAF1 PLBD2 SETBP1 ANKRD11 NLGN2 GREB1 CATSPERG CNOT1

1.03e-0414891011428611215
Pubmed

The protein tyrosine kinase family of the human genome.

EPHB6 MATK INSR ALK

1.03e-0483101411114734
Pubmed

Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.

COPA NLRP1 PPP6R1 CDCP1 LRRTM2 ALDH2

1.08e-04257101630945288
Pubmed

Pax6 is required for delta-catenin/neurojugin expression during retinal, cerebellar and cortical development in mice.

SFRP2 CTNND2

1.24e-046101216973151
Pubmed

Stromal cell-derived factor-1 (SDF-1) enhances cells invasion by αvβ6 integrin-mediated signaling in ovarian cancer.

ITGAV PIK3CA

1.24e-046101223615713
Pubmed

Periostin supports hematopoietic progenitor cells and niche-dependent myeloblastoma cells in vitro.

MED1 ITGAV

1.24e-046101227596966
Pubmed

Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population.

UGT1A6 UGT1A1

1.24e-046101219204906
Pubmed

The pentose phosphate pathway of glucose metabolism. Enzyme profiles and transient and steady-state content of intermediates of alternative pathways of glucose metabolism in Krebs ascites cells.

PGD TKT

1.24e-04610125360673
Pubmed

DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia.

PKP4 CTNND2

1.74e-047101225009281
Pubmed

Novel genetic variants contributing to left ventricular hypertrophy: the HyperGEN study.

SFRP2 NPY2R

1.74e-047101219593212
Pubmed

Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein.

INSR PTPRF

1.74e-047101210660596
Pubmed

Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.

EPHB6 INSR ALK

2.17e-0440101330898150
Pubmed

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.

UGT1A6 UGT1A1

2.31e-048101220610558
Pubmed

Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.

UGT1A6 UGT1A1

2.31e-048101222579593
Pubmed

Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk.

UGT1A6 UGT1A1

2.31e-048101215319294
Pubmed

The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF.

PKP4 CTNND2

2.31e-048101211821434
Pubmed

Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation.

UGT1A6 UGT1A1

2.31e-048101217179145
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

COQ5 PKP4 INSR ITGAV TENM3 PIK3CA MAP4K4

2.35e-04421101736976175
Pubmed

Large-scale concatenation cDNA sequencing.

SELENOT ACD NLRP1 SSTR2 GHITM CD79A CTNND2 ARHGAP19

2.58e-0456810189110174
Pubmed

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.

UGT1A6 UGT1A1

2.97e-049101222511988
Pubmed

A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.

UGT1A6 UGT1A1

2.97e-04910121339448
Pubmed

Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene.

SPDYE2 SPDYE2B

2.97e-049101236272447
Pubmed

Frontline Science: Anthrax lethal toxin-induced, NLRP1-mediated IL-1β release is a neutrophil and PAD4-dependent event.

PADI4 NLRP1

2.97e-049101232421904
Pubmed

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.

LCT PGD TKT ALDH2

3.50e-04114101428245920
Pubmed

Large-scale structural analysis of the classical human protein tyrosine phosphatome.

PKP4 INSR ALK

3.51e-0447101319167335
Pubmed

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

UGT1A6 UGT1A1

3.70e-0410101223642732
Pubmed

Negative and positive auto-regulation of BMP expression in early eye development.

SFRP2 SMAD1

3.70e-0410101226407529
Pubmed

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins.

INSR PIK3CA

3.70e-0410101215249583
Pubmed

UDP-glucuronosyltransferases.

UGT1A6 UGT1A1

3.70e-0410101211465080
Pubmed

Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain.

ADCY4 RELN

3.70e-0410101216615126
Pubmed

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

UGT1A6 UGT1A1

3.70e-0410101223371916
Pubmed

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.

UGT1A6 UGT1A1

3.70e-0410101222558097
Pubmed

Discovery and refinement of loci associated with lipid levels.

DNAJC13 UGT1A6 INSR PEPD UGT1A1

3.87e-04211101524097068
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

DNAJC13 COPA MATK PEPD BTAF1 MED1 MYOF TKT MAP4K4

4.31e-04774101915302935
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

PKP4 PPP6R1 PIK3CA CTNND2 MAP4K4

4.49e-04218101533378226
Pubmed

Influence of drug transporters and UGT polymorphisms on pharmacokinetics of phenolic glucuronide metabolite of mycophenolic acid in Japanese renal transplant recipients.

UGT1A6 UGT1A1

4.51e-0411101218695635
Pubmed

Foxd1-dependent signals control cellularity in the renal capsule, a structure required for normal renal development.

SFRP2 SMAD1

4.51e-0411101215634693
Pubmed

Phosphatidylinositol 3,4,5-trisphosphate directs association of Src homology 2-containing signaling proteins with gelsolin.

ITGAV PIK3CA

4.51e-0411101211577104
Pubmed

Phosphatidylinositol 3-kinase p85{alpha} subunit-dependent interaction with BCR/ABL-related fusion tyrosine kinases: molecular mechanisms and biological consequences.

PIK3CA ALK

4.51e-0411101216135792
Pubmed

Precise spatial restriction of BMP signaling in developing joints is perturbed upon loss of embryo movement.

SFRP2 SMAD1

4.51e-0411101229467244
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT1A6 UGT1A1

5.41e-0412101220308471
Pubmed

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

UGT1A6 UGT1A1

5.41e-0412101219419973
Pubmed

Gene mapping in the Chinese hamster and conservation of syntenic groups and Q-band homologies between Chinese hamster and mouse chromosomes.

PEPD PGD

5.41e-041210123863747
Pubmed

Detoxification enzyme polymorphisms are not involved in duodenal adenomatosis in familial adenomatous polyposis.

UGT1A6 UGT1A1

5.41e-0412101218161889
Pubmed

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.

UGT1A6 UGT1A1

5.41e-0412101211434514
Pubmed

Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.

SPDYE2 SPDYE2B

6.38e-0413101215611625
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR2DL5B KIR2DL5A

6.38e-0413101219120281
Pubmed

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

UGT1A6 UGT1A1

6.38e-0413101222085899
Cytoband4q31

NPY2R SMAD1

2.13e-041010124q31
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

RELN ADAMTS8 LRRC4C TENM3 SORCS3 CTNND2 ALK

1.22e-071739976fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN TTC28 PKP4 ITGAV PTPRF TENM3 CD79A

2.14e-07188997a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTC28 ADAMTS8 MYOF TENM3 SETBP1 SORCS3 COL14A1

2.47e-07192997162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS8 MYOF TENM3 PXDNL SETBP1 SORCS3 COL14A1

2.47e-071929973d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS8 MYOF TENM3 PXDNL SETBP1 SORCS3 COL14A1

2.65e-0719499789b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

RELN LRRC4C TENM3 SORCS3 CTNND2 ALK

2.08e-0616899688c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NPY2R DGKH CHRNB3 MYOF SEC24D VWA5A

2.39e-06172996cecfe5cf20f317ea01b4604789e07a14481c4cd6
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS8 MYOF PXDNL SETBP1 SORCS3 COL14A1

4.11e-061899962a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS8 TENM3 PXDNL SETBP1 SORCS3 COL14A1

4.37e-06191996b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PKP4 DGKH DNAH7 MYOF SORCS3 COL14A1

4.37e-061919965a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PKP4 DGKH DNAH7 MYOF SORCS3 COL14A1

4.37e-0619199655ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS8 MYOF TENM3 PXDNL SORCS3 COL14A1

4.50e-06192996f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS8 MYOF TENM3 PXDNL SORCS3 COL14A1

4.50e-06192996deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS8 TENM3 PXDNL SETBP1 SORCS3 COL14A1

4.64e-06193996fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS8 MYOF TENM3 PXDNL SORCS3 COL14A1

4.78e-061949966e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF TENM3 PXDNL SORCS3 COL14A1

5.53e-06199996a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF TENM3 PXDNL SORCS3 COL14A1

5.53e-06199996211c3a08f2d484ab7a3368006767289088f0d957
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF TENM3 PXDNL SORCS3 COL14A1

5.53e-06199996e1849505b92820a219c5a2c35492bdd55579fb48
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts|LPS_only / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF TENM3 PXDNL SORCS3 COL14A1

5.53e-061999961a0add79f4e34078b3475eb11c85a4234bda197c
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

TTC28 ADAMTS8 MYOF PXDNL SORCS3 COL14A1

5.69e-06200996a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell367C-Lymphocytic-NK_cells-NK_cell_C|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HOXB5 PXDNL ETNK2 LRRTM2 WDR72

2.58e-05156995e6798d2b9c2c1fc6525c24f596f25aa85a375651
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

RELN ADAMTS8 TENM3 SORCS3 ALK

3.38e-051659956ed52cb756d21addf46c7f6c457458b01339fe04
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Hematologic-proerythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PADI4 PGD PIGQ TKT ALDH2

3.48e-05166995a1211afc1197d078eb3db0d0f788ecaf4419aa5b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NPY2R DGKH CHRNB3 SEC24D VWA5A

3.90e-0517099584d49a1f2989d98bd0acf9ec2d59f1042fc0f55b
ToppCelldroplet-Marrow-nan-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PADI4 PGD PIGQ TKT ALDH2

4.35e-051749954b749ac9f05776c0c56b74daca833bd0b5704299
ToppCelldroplet-Marrow-nan-21m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PADI4 PGD PIGQ TKT ALDH2

4.60e-05176995f7d8eb90489a6d22240179abeb0aa16ac24615d3
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NPY2R DGKH CHRNB3 MYOF VWA5A

4.60e-05176995ed421d8525108d2f585265d2cf777f07b29f44f0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CDCP1 ITGAV TENM3 SORCS3 MAP4K4

4.85e-05178995a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCellCOPD-Lymphoid-B_Plasma|Lymphoid / Disease state, Lineage and Cell class

ZNF355P MAN1A1 INSR SEC24D CD79A

5.39e-0518299519db653fe04c5e2957eea1f4893b1c1fca4ddcbd
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COQ5 PTPRF LRRTM2 KICS2 ARHGAP19

5.39e-05182995c00e503f442d44fbae73c5e2dc85be69e294e67a
ToppCelldroplet-Marrow-nan-21m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PADI4 PGD PIGQ CD79A ALDH2

5.68e-05184995d071f53ad9e957dc0f8ae9c53aaa31cfebcf815e
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 ADCY4 DGKH CTNND2 SMAD1

5.82e-05185995808d5e880069aff8866cd2c733b9fe568a37701f
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

RELN TENM3 GREB1 CTNND2 MAP4K4

5.82e-051859951d874608aa2062024323512f68889219471b2f00
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

SFRP2 TTC28 SETBP1 COL14A1 GREB1

5.82e-05185995a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

TTC28 SPDYE2 GREB1 CTNND2 MAP4K4

5.98e-05186995de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

TTC28 SPDYE2 GREB1 CTNND2 MAP4K4

5.98e-051869950b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS8 TENM3 PXDNL SORCS3 COL14A1

6.44e-05189995a153b83314cf52808f685296cff8c95af3f4983d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS8 TENM3 PXDNL SORCS3 COL14A1

6.44e-05189995e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac|lymph-node_spleen / Manually curated celltypes from each tissue

CDCP1 MYOF DHRS9 MMP1 ALDH2

6.44e-05189995aac79c41ce7acba722c45c016b2c6997fb772a96
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PITPNM2 PKP4 ITGAV CHRNB3 SORCS3

6.44e-051899958c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PITPNM2 PKP4 ITGAV CHRNB3 SORCS3

6.44e-051899955d902a4660a27548764bf04c6de152b565da835c
ToppCelldroplet-Heart-nan-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB6 RELN ADAMTS8 PTPRF ARHGAP19

6.44e-051899950493f7b79127c207fd7ade778ef4810500495d7e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PKP4 DGKH DNAH7 MYOF SORCS3

6.61e-051909953fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCARE TENM3 PXDNL GREB1 ALK

6.61e-0519099539ab890104b4264c68a968f920f4ccd84f0bc681
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN TTC28 PKP4 PTPRF CD79A

6.77e-051919953387b95a3f2445c672d407922fdce3a91eabaef8
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS8 TENM3 PXDNL SORCS3 COL14A1

6.94e-051929956f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 ADCY4 PKP4 CTNND2 SMAD1

6.94e-051929950aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS8 TENM3 PXDNL SORCS3 COL14A1

6.94e-05192995dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS8 MYOF TENM3 SORCS3 COL14A1

6.94e-051929954e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS8 MYOF TENM3 SORCS3 COL14A1

6.94e-05192995ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN1A1 MYOF SEC24D PTPRF COL14A1

6.94e-051929950dc1f46e40346ed0b286e53b106a812441575100
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

TTC28 INSR SETBP1 ANKRD11 WDR72

6.94e-05192995e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 PKP4 DGKH CTNND2 SMAD1

7.11e-05193995e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 PKP4 DGKH CTNND2 SMAD1

7.11e-051939956e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PITPNM2 DGKH CDCP1 DNAH7 MYOF

7.11e-05193995f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PITPNM2 DGKH CDCP1 DNAH7 MYOF

7.11e-0519399542df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature-Adult_Glia|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN ADAMTS8 LRRC4C TENM3 ALK

7.29e-05194995d429bb5e422a07bd92f0dc48cd51528e8b7d9a72
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS8 TENM3 PXDNL SORCS3 COL14A1

7.29e-0519499560622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 PKP4 DGKH CTNND2 SMAD1

7.29e-051949950b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

SPATA20 CAMTA2 ITLN2 PIGQ PTPRF

7.29e-0519499588db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 PKP4 DGKH CTNND2 SMAD1

7.29e-0519499558f069efdefa0366033764446b9d6ffd4a17807e
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

SPATA20 CAMTA2 ITLN2 PIGQ PTPRF

7.29e-05194995a71728202493d4858342ea2756ea281cd0d99a3a
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 PKP4 DGKH CTNND2 SMAD1

7.29e-05194995bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCell3'-Pediatric_IBD-SmallIntestine-Neuronal|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN ADAMTS8 LRRC4C TENM3 ALK

7.29e-05194995bffdf6db0bf3fb338e7bb0789ae7dcde1fce0094
ToppCell3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN ADAMTS8 LRRC4C TENM3 ALK

7.29e-05194995408dfc7060095972a54ae37ae8105521df6fbbee
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SFRP2 TTC28 TENM3 SETBP1 COL14A1

7.65e-05196995dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF TENM3 SORCS3 COL14A1

7.84e-05197995fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellNS-critical-LOC-Myeloid-Macrophage|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PEPD ITGAV PLBD2 MYOF ALDH2

7.84e-051979955fb0696376a5501b7c87e0f2f5e4fff3da2903f2
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF PXDNL SORCS3 COL14A1

8.03e-051989950a4b19c3d5e65ecd24fc2ce80ac5276c813282c7
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF TENM3 SORCS3 COL14A1

8.22e-05199995ba586690f88fd051f449753bfe7603a2cb431782
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF TENM3 SORCS3 COL14A1

8.22e-0519999538ed3bc7daa993d9edcf3e7834597ebb06dd24f8
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF TENM3 SORCS3 COL14A1

8.22e-0519999506a7d874ff7c4616577f6e59d3118717a8c47c00
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF PXDNL SORCS3 COL14A1

8.22e-0519999530d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF TENM3 SORCS3 COL14A1

8.22e-051999958b86c69aaf60feff53aa782559cfece7342a23de
ToppCellsevere_influenza-Classical_Monocyte|World / disease group, cell group and cell class (v2)

PADI4 PGD MYOF TKT ALDH2

8.22e-05199995b8adbd6ff5e5602259118a69fd7c77e8348a27e4
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF PXDNL SORCS3 COL14A1

8.41e-052009959b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PITPNM2 ADCY4 PKP4 DGKH SMAD1

8.41e-05200995dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellCOVID_vent-Myeloid|COVID_vent / Disease condition, Lineage, Cell class and subclass

PADI4 PGD MYOF TKT ALDH2

8.41e-05200995621af09aae34226902c03edf556562f3ab35a7d8
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF PXDNL SORCS3 COL14A1

8.41e-05200995b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF PXDNL SORCS3 COL14A1

8.41e-0520099550ca6550998e461ef26dd670351060bd940765a8
ToppCellsevere_influenza|World / disease group, cell group and cell class (v2)

PADI4 PGD MYOF TKT ALDH2

8.41e-052009952c965ec0c33a797c227a06dac90b5ecb959816f6
ToppCellControl_saline-Endothelial-Endothelial-Gen_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

PITPNM2 ADCY4 PKP4 MAP4K4 SMAD1

8.41e-052009953b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCellInfluenza|World / Disease, condition lineage and cell class

PADI4 PGD MYOF TKT ALDH2

8.41e-05200995df996c35907a1c9194b9e2ca30e81f520ca067f0
ToppCellLPS_IL1RA-Endothelial-Endothelial-Vein|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ADCY4 MAN1A1 PKP4 LRRC4C RP9

8.41e-05200995b3f93b71589251197cde96b7bc6d065c106f61cd
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF PXDNL SORCS3 COL14A1

8.41e-052009953bdba9612cd7c612b76aa9abecc4a6529aabfc1c
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PITPNM2 ADCY4 PKP4 DGKH SMAD1

8.41e-05200995a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF PXDNL SORCS3 COL14A1

8.41e-0520099544a68bacdb3d5bf563bd35952176995850933a81
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ADAMTS8 MYOF PXDNL SORCS3 COL14A1

8.41e-05200995dc61016c61729f69649cfb21f6264e685ce83dea
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2_(Retrosplenial_cortex_(RSG)/Subiculum/Parasubiculum)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PADI4 CDCP1 CD79A

1.66e-0448993e96a608c2239f2ceb07d0a492289b24fabf190a1
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2_(Retrosplenial_cortex_(RSG)/Subiculum/Parasubiculum)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PADI4 CDCP1 CD79A

1.66e-044899317cb229b199c49ec74d2230b1f8dbb0195b1bf01
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Excitatory_Neuron.Slc17a7-Slc17a6.Tshz2_(Retrosplenial_cortex_(RSG)/Subiculum/Parasubiculum)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PADI4 CDCP1 CD79A

1.66e-0448993c030dfb7c3289df7f34e91f31be6e9b47ca045f5
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SFRP2 PXDNL COL14A1 NLGN2

1.74e-04125994b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Shisa8_(Layer_5,_medial_posterior_cortex_(Retrosplenial_cortex_(RSG),_subiculum))-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC6A18 CD79A OTOG

1.77e-04499933eca54d2c8426e6d78a4a3b261f9a5ad786515a3
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Tshz2-Excitatory_Neuron.Slc17a7-Slc17a6.Shisa8_(Layer_5,_medial_posterior_cortex_(Retrosplenial_cortex_(RSG),_subiculum))|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC6A18 CD79A OTOG

1.77e-04499937ea79acc4a7210c32181d4b306b07fe35f598dae
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN SFRP2 MAN1A1 LCT

1.80e-0412699494bd9cfe982b41a3114885173eab55feb0fbbbae
ToppCellPND01-03-samps-Lymphocyte-B_cell-B_cell_1|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SAMD9L CD79A XKR5 RASAL1

1.91e-041289945d82247ceda55017628720ed8b6c36ff7cec8437
ToppCellPND01-03-samps-Lymphocyte|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SAMD9L CD79A XKR5 RASAL1

1.91e-04128994d3158825a2178244b57ac5ad2676617fd58d8466
ToppCellPND01-03-samps-Lymphocyte-B_cell|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SAMD9L CD79A XKR5 RASAL1

1.91e-041289947661402dd7cd533c1bfe8d9247cecd88c1be9a5e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN VWA5A COL14A1 WDR72

2.09e-041319949ca209a8652aae603c4a867ea06b06ac51e7d189
ToppCellprimary_visual_cortex|World / Per Region, Lineage, Cell class, Cell type, Cell subtype

PITPNM2 SSTR2 ITGAV TENM3

2.76e-04141994605d7b28e99c943f64b4095855a6f9f70e92cb09
DrugDiphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A

EPHB6 RELN TTC28 MYOF SEC24D VWA5A COL14A1 CD79A

1.96e-061969786061_UP
Drug5-MOP

UGT1A6 UGT1A1 RP9 SMAD1

3.66e-0625974CID000002355
DiseaseOvarian cyst

TTC28 GREB1

9.77e-055932HP_0000138
Diseasemacula measurement

PITPNM2 SFRP2 CDCP1 CTNND2 WDR72

3.37e-04189935EFO_0008375
DiseaseX-11442 measurement

UGT1A6 UGT1A1

3.49e-049932EFO_0021236
DiseaseX-11441 measurement

UGT1A6 UGT1A1

3.49e-049932EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A6 UGT1A1

3.49e-049932EFO_0004739
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A6 UGT1A1

3.49e-049932EFO_0004570, GO_0009410
Diseasebilirubin measurement, response to tenofovir

UGT1A6 UGT1A1

4.35e-0410932EFO_0004570, EFO_0009279
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A6 UGT1A1

4.35e-0410932EFO_0802185
Diseasehistidine betaine (hercynine) measurement

UGT1A6 UGT1A1

5.31e-0411932EFO_0800972
DiseaseX-21796 measurement

UGT1A6 UGT1A1

5.31e-0411932EFO_0800825
Diseaseinsomnia, bilirubin measurement

UGT1A6 UGT1A1

5.31e-0411932EFO_0004570, EFO_0004698
Diseasealdosterone measurement

UGT1A6 UGT1A1

5.31e-0411932EFO_0010219
Diseasebiliverdin measurement

UGT1A6 UGT1A1

6.35e-0412932EFO_0021033
Diseaseabdominal aortic aneurysm (is_implicated_in)

ITGAV MMP1

6.35e-0412932DOID:7693 (is_implicated_in)
DiseaseDiffuse Large B-Cell Lymphoma

PIK3CA CD79A ALK

7.06e-0455933C0079744
Diseaseovarian cancer (is_implicated_in)

UGT1A1 PIK3CA MMP1

7.44e-0456933DOID:2394 (is_implicated_in)
DiseaseCocaine Dependence

NPY2R CHRNB3 TENM3 SMAD1

9.95e-04139934C0600427
DiseaseBMI-adjusted adiponectin measurement

PEPD ALK

1.00e-0315932EFO_0007737
Diseasecutaneous Leishmaniasis

PPP6R1 PXDNL

1.15e-0316932EFO_0005046
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

UGT1A6 INSR UGT1A1 MMP1

1.22e-03147934DOID:9352 (biomarker_via_orthology)
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A6 UGT1A1

1.30e-0317932EFO_0004611, EFO_0007800
DiseaseAbdominal Aortic Aneurysm

PKP4 ADAMTS8 ABHD16B

1.31e-0368933EFO_0004214
DiseaseAntihypertensive use measurement

PKP4 INSR PXDNL TKT SORCS3

1.54e-03265935EFO_0009927
DiseaseAlcoholic Intoxication, Chronic

NPY2R CHRNB3 TKT ALDH2 ALK

1.61e-03268935C0001973
Diseaserenal system measurement

ALDH2 WDR72

1.80e-0320932EFO_0004742
Diseasetemporal lobe epilepsy (is_marker_for)

RELN NPY2R

1.80e-0320932DOID:3328 (is_marker_for)
Diseasecerebellar cortex volume measurement

LRRC4C PXDNL

1.98e-0321932EFO_0010291
DiseaseCOVID-19, mortality

TTC28 NLRP1 LRRC4C TENM3

2.08e-03170934EFO_0004352, MONDO_0100096
DiseaseHodgkin Disease

RELN UGT1A1

2.18e-0322932C0019829
DiseaseDown syndrome (is_marker_for)

RELN GART

2.18e-0322932DOID:14250 (is_marker_for)
Diseasepallidum volume

CHRNB3 WDR72

2.81e-0325932EFO_0006933

Protein segments in the cluster

PeptideGeneStartEntry
LSKSPKGVEMLWHPS

PKP4

811

Q99569
VPLLPQNGFWTLEMH

BTN2A3P

381

Q96KV6
FPSKGWQVHISLKLM

CATSPERG

551

Q6ZRH7
MNLYLHPKLWPQLAG

DIAPH2-AS1

1

Q14236
GSVLIFTPALKMWLH

CHRNB3

441

Q05901
HPFKATVLVWIQLPM

COX18

166

Q8N8Q8
SKDWLAGPHMKEVLP

ANKRD11

1676

Q6UB99
GVKMALHLPWFHPRN

CDCP1

191

Q9H5V8
VMAPLFVHLNQTLPW

ADAMTS8

391

Q9UP79
LLGQLKPMFHGIKWS

CAMTA2

181

O94983
LMPGGNKEAWPHIKT

PGD

141

P52209
KGPKMLHWLPALSGL

ADCY4

641

Q8NFM4
LGPGCQALWMHKVPA

CD79A

26

P11912
KGIQMLWHPSIVKPY

CTNND2

836

Q9UQB3
VPLALKVMPHSWKGL

ABHD16B

276

Q9H3Z7
LGQGKELWMAPLHPF

RASAL1

516

O95294
FVPRLPASHATWMGK

PEPD

96

P12955
WKMGPVLCHLVPYAQ

NPY2R

116

P49146
FWKSILMGPVTPAHA

KIR2DL5A

76

Q8N109
SVVLGPKWPSHYLMV

PADI4

226

Q9UM07
KKSPPGHDDQLWLVM

MAP4K4

91

O95819
MGLHFKWPLGAPMLA

LRRTM2

1

O43300
LSADPKLSLMPWFHG

MATK

111

P42679
KLSLMPWFHGKISGQ

MATK

116

P42679
KYWPNHIMLVLPSIF

GREB1

1586

Q4ZG55
PGPKHLAWLLHSGVM

GHITM

186

Q9H3K2
FLDSMQPKHLPQQWS

EXD2

586

Q9NVH0
FWKSILMGPVTPAHA

KIR2DL5B

76

Q8NHK3
LMGTKHLIAAFWAPV

MFSD6L

51

Q8IWD5
HANGSLPKPILWHKM

ETNK2

186

Q9NVF9
PQHSWMVAGPLLDIK

NLRP1

1141

Q9C000
PMATLFHWDLPQALQ

LCT

491

P09848
PGSFQGLMHLQKLWM

LRRC4C

236

Q9HCJ2
KSQNHPGWLMRGLKP

INSR

571

P06213
GMHIPSWFRSILPKA

PITPNM2

66

Q9BZ72
MPHQWLEGNLPVSAK

DGKH

246

Q86XP1
LVSGKMALNLWPVPH

PIK3CA

436

P42336
DSRKWLLHPGGTKMP

RELN

2331

P78509
GQTPQIFPWMRKLHI

HOXB5

171

P09067
QKAVQPPHLFLWLMK

KICS2

246

Q96MD2
GNLGLMALIWKDPHL

OR5AC1

41

P0C628
HWLPKVLGDPGTRML

PXDNL

1016

A1KZ92
PLHIISIKPSTMWFG

DCLRE1C

281

Q96SD1
LPHLWDAMVGPLRNT

BTAF1

1046

O14981
PLSADEGLHKLMWIP

COL14A1

646

Q05707
RGVNWAAFHPTMPLI

COPA

206

P53621
GPSSFSKAMLHLQWP

ITGAV

816

P06756
ALPQLSMVSTKPHWQ

DNAH7

41

Q8WXX0
PTHKGQRWGLLSMPV

DNAJC13

336

O75165
FHTPSGIPWALLNMK

MAN1A1

316

P33908
AKDLGIWHVPNKSPM

ITLN2

156

Q8WWU7
DLLLWKMHPLPGTQL

COQ5

96

Q5HYK3
LNWMLKSPPGHFGLL

nan

26

Q6ZN92
WIPLSHMPAALQDFL

DHRS9

291

Q9BPW9
MLLLLIFWIAPAHGP

NIPA1

171

Q7RTP0
HGALPAIMLPVWFTD

NLGN2

111

Q8NFZ4
APLIMGSHPVDNKWT

MED1

271

Q15648
AHPWIFLLAPLMLTA

PTCHD3

136

Q3KNS1
TAMNTALLQWHPPKE

PTPRF

831

P10586
SLKMGIGWKPLAPIF

PCARE

791

A6NGG8
ANLGHLNWPPFCLVM

OTOG

2156

Q6ZRI0
MPVQLPLAHSGWLFK

POLR3D

176

P05423
VPVWSKLESGHLPSM

SELENOT

156

P62341
AGAWIPLVMKQCHPD

SFRP2

76

Q96HF1
HAPTKGLWMPLGKEV

RP9

86

Q8TA86
FPLRETPMAGLHQWK

LRRC28

331

Q86X40
MHSFPPLLLLLFWGV

MMP1

1

P03956
LPPAHFRKMWALATG

PLEKHG4

601

Q58EX7
WGGALVAMKHTPLPV

SORCS3

616

Q9UPU3
KHMVQFLSGKWTIPP

SAMD9L

1226

Q8IVG5
CPPGLHLLMLDTWQK

EPHB6

886

O15197
QHLLQWLMGAPAGLK

PIGQ

321

Q9BRB3
IPLLRKPWFQLGHSM

SPDYE2B

281

A6NHP3
LPFLAMQVALVHWPF

SSTR2

96

P30874
HMFLWLGVSSPPELI

SEC24D

926

O94855
MHLNATWPKRVAQLP

SLC6A18

351

Q96N87
WLDKVLTQMGSPHNP

SMAD1

446

Q15797
AVRLPPQLMAWALHF

ACD

431

Q96AP0
LLMPTPGKHGWTVLQ

ALK

376

Q9UM73
NFPLLMQAWKLGPAL

ALDH2

186

P05091
ISWISAPLPVGAMKH

C11orf40

116

Q8WZ69
GPVISHLKLTMYPWG

NDUFV1-DT

116

Q8NBR9
GHWLGMITLAKNKPI

CNOT1

1196

A5YKK6
SWHGKPLPKNMAEQI

TKT

256

P29401
NLILHCPKFWPFAML

TMEM144

56

Q7Z5S9
IPLLRKPWFQLGHSM

SPDYE2

281

Q495Y8
LDFLWHNMKLPVPAA

TBL3

781

Q12788
PKPHLDSKMLAAWNG

SPATA20

496

Q8TB22
PSLVLIHKDMGLGAW

ZNF408

696

Q9H9D4
LVKWLPQNDLLGHPM

UGT1A1

351

P22309
WGQKAPPHSITAIMI

WDR72

11

Q3MJ13
HPTLWLPSSKLMAVN

TENM3

1806

Q9P273
LSWHLPPGLSAKMLS

VWA5A

471

O00534
NLALMFAPHVLWPKN

ARHGAP19

266

Q14CB8
KWNGKMLNIHPSLLP

GART

906

P22102
DFLLQPPHLQAMVAW

PPP6R1

46

Q9UPN7
SLWPVPVAASKMFIH

TTC28

1656

Q96AY4
PWSMKHPGLTQHNIV

ZNF355P

51

Q9NSJ1
PFSGLLHMGQPDLWK

PLBD2

566

Q8NHP8
LHMGQPDLWKFAPVK

PLBD2

571

Q8NHP8
VKWLPQNDLLGHPMT

UGT1A6

351

P19224
FMKPGHLAMPWAALF

XKR5

166

Q6UX68
GIHSGTWKLSPPRLM

SETBP1

821

Q9Y6X0
PGHAVMRKWLLLNDP

MYOF

291

Q9NZM1