Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	delayed rectifier potassium channel activity	KCNA1 KCNA2 KCNA3 KCNA4	1.00e-06	28	55	4	GO:0005251
GeneOntologyMolecularFunction	hepoxilin-epoxide hydrolase activity	ALOX12 ALOX15	7.45e-06	2	55	2	GO:0047977
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	KCNA1 KCNA2 KCNA4	1.31e-05	17	55	3	GO:0099508
GeneOntologyMolecularFunction	linoleate 13S-lipoxygenase activity	ALOX12 ALOX15	2.23e-05	3	55	2	GO:0016165
GeneOntologyMolecularFunction	arachidonate 15-lipoxygenase activity	ALOX12 ALOX15	2.23e-05	3	55	2	GO:0050473
GeneOntologyMolecularFunction	arachidonate 12(S)-lipoxygenase activity	ALOX12 ALOX15	4.45e-05	4	55	2	GO:0004052
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	KCNA1 KCNA2	1.11e-04	6	55	2	GO:1905030
GeneOntologyMolecularFunction	dioxygenase activity	PHF2 KDM5A ALOX12 ALOX15	1.54e-04	98	55	4	GO:0051213
GeneOntologyMolecularFunction	voltage-gated potassium channel activity	KCNA1 KCNA2 KCNA3 KCNA4	1.79e-04	102	55	4	GO:0005249
GeneOntologyMolecularFunction	phosphatidylinositol bisphosphate binding	SVIL KIF16B PLCD1 ALOX15	3.45e-04	121	55	4	GO:1902936
GeneOntologyMolecularFunction	epoxide hydrolase activity	ALOX12 ALOX15	4.03e-04	11	55	2	GO:0004301
GeneOntologyMolecularFunction	potassium channel activity	KCNA1 KCNA2 KCNA3 KCNA4	4.27e-04	128	55	4	GO:0005267
GeneOntologyMolecularFunction	hydrolase activity, acting on ether bonds	ALOX12 ALOX15	5.70e-04	13	55	2	GO:0016801
GeneOntologyMolecularFunction	ether hydrolase activity	ALOX12 ALOX15	5.70e-04	13	55	2	GO:0016803
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	KCNA1 KCNA2 KCNA3 KCNA4	8.14e-04	152	55	4	GO:0022843
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	KCNA1 KCNA2 KCNA3 KCNA4	1.15e-03	167	55	4	GO:0015079
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	KCNA1 KCNA2 KCNA3 KCNA4	1.58e-03	182	55	4	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	KCNA1 KCNA2 KCNA3 KCNA4	1.65e-03	184	55	4	GO:0022832
GeneOntologyMolecularFunction	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	ALOX12 ALOX15	2.15e-03	25	55	2	GO:0016702
GeneOntologyMolecularFunction	phosphatidylinositol phosphate binding	SVIL KIF16B PLCD1 ALOX15	2.19e-03	199	55	4	GO:1901981
GeneOntologyMolecularFunction	gated channel activity	ANO2 KCNA1 KCNA2 KCNA3 KCNA4	2.23e-03	334	55	5	GO:0022836
GeneOntologyMolecularFunction	phosphatidylinositol-4,5-bisphosphate binding	SVIL PLCD1 ALOX15	2.29e-03	95	55	3	GO:0005546
GeneOntologyMolecularFunction	phosphatidylinositol phospholipase C activity	CASR PLCD1	2.32e-03	26	55	2	GO:0004435
GeneOntologyMolecularFunction	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	ALOX12 ALOX15	2.32e-03	26	55	2	GO:0016701
GeneOntologyMolecularFunction	modification-dependent protein binding	PHF2 ANKRD13A KDM5A BRCC3	2.49e-03	206	55	4	GO:0140030
GeneOntologyMolecularFunction	outward rectifier potassium channel activity	KCNA2 KCNA3	2.50e-03	27	55	2	GO:0015271
GeneOntologyMolecularFunction	histone H3 demethylase activity	PHF2 KDM5A	2.69e-03	28	55	2	GO:0141052
GeneOntologyMolecularFunction	actin monomer binding	PRKCE LMOD2	2.88e-03	29	55	2	GO:0003785
GeneOntologyMolecularFunction	phospholipase C activity	CASR PLCD1	2.88e-03	29	55	2	GO:0004629
GeneOntologyMolecularFunction	histone demethylase activity	PHF2 KDM5A	3.29e-03	31	55	2	GO:0032452
GeneOntologyMolecularFunction	protein demethylase activity	PHF2 KDM5A	3.50e-03	32	55	2	GO:0140457
GeneOntologyMolecularFunction	demethylase activity	PHF2 KDM5A	6.54e-03	44	55	2	GO:0032451
GeneOntologyBiologicalProcess	regulation of presynaptic membrane potential	KCNA1 KCNA2 KCNA4 CASR	1.32e-06	32	53	4	GO:0099505
GeneOntologyBiologicalProcess	regulation of actin cytoskeleton organization	CRACD CSF1R PPM1F SVIL PRKCE LMOD2 ALOX15 HDAC2	5.72e-06	384	53	8	GO:0032956
GeneOntologyBiologicalProcess	response to morphine	PPP2R2A PPP1R1B PRKCE	7.13e-06	15	53	3	GO:0043278
GeneOntologyBiologicalProcess	response to isoquinoline alkaloid	PPP2R2A PPP1R1B PRKCE	8.76e-06	16	53	3	GO:0014072
GeneOntologyBiologicalProcess	regulation of actin filament-based process	CRACD CSF1R PPM1F SVIL PRKCE LMOD2 ALOX15 HDAC2	1.49e-05	438	53	8	GO:0032970
GeneOntologyBiologicalProcess	positive regulation of actin filament polymerization	CRACD PRKCE LMOD2 ALOX15	1.59e-05	59	53	4	GO:0030838
GeneOntologyBiologicalProcess	lipoxin A4 biosynthetic process	ALOX12 ALOX15	1.94e-05	3	53	2	GO:2001303
GeneOntologyBiologicalProcess	optic nerve development	KCNA1 KCNA2 KCNA3	2.38e-05	22	53	3	GO:0021554
GeneOntologyBiologicalProcess	lipoxin A4 metabolic process	ALOX12 ALOX15	3.87e-05	4	53	2	GO:2001302
GeneOntologyBiologicalProcess	lipoxin biosynthetic process	ALOX12 ALOX15	3.87e-05	4	53	2	GO:2001301
GeneOntologyBiologicalProcess	regulation of actin filament polymerization	CRACD SVIL PRKCE LMOD2 ALOX15	4.97e-05	156	53	5	GO:0030833
GeneOntologyBiologicalProcess	lipoxin metabolic process	ALOX12 ALOX15	6.45e-05	5	53	2	GO:2001300
GeneOntologyBiologicalProcess	corpus callosum development	KCNA1 KCNA2 KCNA3	8.28e-05	33	53	3	GO:0022038
GeneOntologyBiologicalProcess	regulation of actin polymerization or depolymerization	CRACD SVIL PRKCE LMOD2 ALOX15	9.04e-05	177	53	5	GO:0008064
GeneOntologyBiologicalProcess	regulation of actin filament length	CRACD SVIL PRKCE LMOD2 ALOX15	9.79e-05	180	53	5	GO:0030832
GeneOntologyBiologicalProcess	regulation of cytoskeleton organization	CRACD CSF1R PPM1F SVIL PRKCE LMOD2 ALOX15 HDAC2	1.07e-04	579	53	8	GO:0051493
GeneOntologyBiologicalProcess	regulation of actin filament organization	CRACD PPM1F SVIL PRKCE LMOD2 ALOX15	1.16e-04	300	53	6	GO:0110053
GeneOntologyBiologicalProcess	regulation of supramolecular fiber organization	CRACD PPM1F SVIL PRKCE LMOD2 ALOX15 HDAC2	1.23e-04	438	53	7	GO:1902903
GeneOntologyBiologicalProcess	actin filament polymerization	CRACD SVIL PRKCE LMOD2 ALOX15	1.26e-04	190	53	5	GO:0030041
GeneOntologyBiologicalProcess	positive regulation of protein polymerization	CRACD PRKCE LMOD2 ALOX15	1.37e-04	102	53	4	GO:0032273
GeneOntologyBiologicalProcess	positive regulation of supramolecular fiber organization	CRACD PPM1F PRKCE LMOD2 ALOX15	1.46e-04	196	53	5	GO:1902905
GeneOntologyBiologicalProcess	lacrimal gland development	SOX9 SOX10	1.80e-04	8	53	2	GO:0032808
GeneOntologyBiologicalProcess	hepoxilin metabolic process	ALOX12 ALOX15	1.80e-04	8	53	2	GO:0051121
GeneOntologyBiologicalProcess	hepoxilin biosynthetic process	ALOX12 ALOX15	1.80e-04	8	53	2	GO:0051122
GeneOntologyBiologicalProcess	positive regulation of cytoskeleton organization	CRACD PPM1F PRKCE LMOD2 ALOX15	1.80e-04	205	53	5	GO:0051495
GeneOntologyBiologicalProcess	central nervous system development	SOX9 SOX10 SOX15 KCNA1 KCNA2 KCNA3 CSF1R SPEF2 HDAC2 EXOC4 PCNT	1.92e-04	1197	53	11	GO:0007417
GeneOntologyBiologicalProcess	telencephalon development	KCNA1 KCNA2 KCNA3 CSF1R HDAC2 PCNT	2.02e-04	332	53	6	GO:0021537
GeneOntologyBiologicalProcess	actin filament capping	CRACD SVIL LMOD2	2.25e-04	46	53	3	GO:0051693
GeneOntologyBiologicalProcess	regulation of protein-containing complex assembly	SOX9 CRACD SVIL PRKCE BRCC3 LMOD2 ALOX15	2.42e-04	489	53	7	GO:0043254
GeneOntologyBiologicalProcess	actin polymerization or depolymerization	CRACD SVIL PRKCE LMOD2 ALOX15	2.60e-04	222	53	5	GO:0008154
GeneOntologyBiologicalProcess	positive regulation of protein-containing complex assembly	CRACD PRKCE BRCC3 LMOD2 ALOX15	2.88e-04	227	53	5	GO:0031334
GeneOntologyBiologicalProcess	response to alkaloid	PPP2R2A PPP1R1B PRKCE HDAC2	2.99e-04	125	53	4	GO:0043279
GeneOntologyBiologicalProcess	regulation of protein polymerization	CRACD SVIL PRKCE LMOD2 ALOX15	3.13e-04	231	53	5	GO:0032271
GeneOntologyBiologicalProcess	negative regulation of actin filament depolymerization	CRACD SVIL LMOD2	3.24e-04	52	53	3	GO:0030835
GeneOntologyBiologicalProcess	lipoxygenase pathway	ALOX12 ALOX15	3.51e-04	11	53	2	GO:0019372
GeneOntologyBiologicalProcess	oligodendrocyte differentiation	SOX9 SOX10 HDAC2 EXOC4	4.24e-04	137	53	4	GO:0048709
GeneOntologyBiologicalProcess	head development	SOX9 SOX15 KCNA1 KCNA2 KCNA3 CSF1R SPEF2 HDAC2 PCNT	5.04e-04	919	53	9	GO:0060322
GeneOntologyBiologicalProcess	regulation of actin filament depolymerization	CRACD SVIL LMOD2	5.19e-04	61	53	3	GO:0030834
GeneOntologyBiologicalProcess	regulation of membrane potential	KCNA1 KCNA2 KCNA3 KCNA4 PRKCE CASR ALOX12	5.41e-04	559	53	7	GO:0042391
GeneOntologyBiologicalProcess	actin filament depolymerization	CRACD SVIL LMOD2	6.54e-04	66	53	3	GO:0030042
GeneOntologyBiologicalProcess	cranial nerve development	KCNA1 KCNA2 KCNA3	6.83e-04	67	53	3	GO:0021545
GeneOntologyBiologicalProcess	positive regulation of cellular component biogenesis	SOX9 CRACD PPM1F PRKCE BRCC3 LMOD2 ALOX15	6.87e-04	582	53	7	GO:0044089
GeneOntologyBiologicalProcess	heterochromatin formation	PHF2 KDM5A SMCHD1 HDAC2	8.14e-04	163	53	4	GO:0031507
GeneOntologyBiologicalProcess	negative regulation of actin filament polymerization	CRACD SVIL LMOD2	9.49e-04	75	53	3	GO:0030837
GeneOntologyBiologicalProcess	actin cytoskeleton organization	CRACD CSF1R PPM1F SVIL PRKCE LMOD2 ALOX15 HDAC2	9.56e-04	803	53	8	GO:0030036
GeneOntologyBiologicalProcess	protein complex oligomerization	CD247 KCNA1 KCNA2 KCNA3 KCNA4	9.61e-04	296	53	5	GO:0051259
GeneOntologyBiologicalProcess	negative regulation of protein-containing complex assembly	SOX9 CRACD SVIL LMOD2	1.02e-03	173	53	4	GO:0031333
GeneOntologyBiologicalProcess	positive regulation of myoblast proliferation	SOX15 CSF1R	1.08e-03	19	53	2	GO:2000288
GeneOntologyBiologicalProcess	positive regulation of cell cycle process	SOX15 CSF1R SVIL SMC6 PRKCE	1.13e-03	307	53	5	GO:0090068
GeneOntologyCellularComponent	glutamatergic synapse	ANO2 PPP2R2A KCNA1 KCNA2 KCNA3 KCNA4 PPP1R1B PRKCE CASR ERBIN	4.66e-05	817	55	10	GO:0098978
GeneOntologyCellularComponent	axon initial segment	KCNA1 KCNA2 KCNA4	6.00e-05	29	55	3	GO:0043194
GeneOntologyCellularComponent	voltage-gated potassium channel complex	KCNA1 KCNA2 KCNA3 KCNA4	9.67e-05	91	55	4	GO:0008076
GeneOntologyCellularComponent	calyx of Held	KCNA1 KCNA2 KCNA3	1.16e-04	36	55	3	GO:0044305
GeneOntologyCellularComponent	potassium channel complex	KCNA1 KCNA2 KCNA3 KCNA4	1.62e-04	104	55	4	GO:0034705
GeneOntologyCellularComponent	axon terminus	KCNA1 KCNA2 KCNA3 CABP4 CASR	2.26e-04	210	55	5	GO:0043679
GeneOntologyCellularComponent	neuron projection terminus	KCNA1 KCNA2 KCNA3 CABP4 CASR	3.64e-04	233	55	5	GO:0044306
GeneOntologyCellularComponent	juxtaparanode region of axon	KCNA1 KCNA2	4.41e-04	12	55	2	GO:0044224
GeneOntologyCellularComponent	presynapse	ANO2 KCNA1 KCNA2 KCNA3 KCNA4 CABP4 PRKCE CASR EXOC4	4.67e-04	886	55	9	GO:0098793
GeneOntologyCellularComponent	presynaptic membrane	ANO2 KCNA1 KCNA2 KCNA3 KCNA4	7.98e-04	277	55	5	GO:0042734
GeneOntologyCellularComponent	distal axon	KCNA1 KCNA2 KCNA3 CABP4 CASR EXOC4	9.61e-04	435	55	6	GO:0150034
GeneOntologyCellularComponent	main axon	KCNA1 KCNA2 KCNA4	1.67e-03	89	55	3	GO:0044304
Domain	K_chnl_volt-dep_Kv1	KCNA1 KCNA2 KCNA3 KCNA4	4.33e-09	8	54	4	IPR003972
Domain	K_chnl_volt-dep_Kv	KCNA1 KCNA2 KCNA3 KCNA4	1.04e-06	27	54	4	IPR003968
Domain	VG_K_chnl	KCNA1 KCNA2 KCNA3 KCNA4	2.40e-06	33	54	4	IPR028325
Domain	BTB_2	KCNA1 KCNA2 KCNA3 KCNA4	1.65e-05	53	54	4	PF02214
Domain	T1-type_BTB	KCNA1 KCNA2 KCNA3 KCNA4	1.65e-05	53	54	4	IPR003131
Domain	Channel_four-helix_dom	KCNA1 KCNA2 KCNA3 KCNA4	2.20e-05	57	54	4	IPR027359
Domain	-	KCNA1 KCNA2 KCNA3 KCNA4	2.20e-05	57	54	4	1.20.120.350
Domain	Sox_N	SOX9 SOX10	2.46e-05	3	54	2	IPR022151
Domain	Sox_N	SOX9 SOX10	2.46e-05	3	54	2	PF12444
Domain	LipOase_mml	ALOX12 ALOX15	1.22e-04	6	54	2	IPR001885
Domain	LIPOXYGENASE_1	ALOX12 ALOX15	1.22e-04	6	54	2	PS00711
Domain	LipOase_C	ALOX12 ALOX15	1.22e-04	6	54	2	IPR013819
Domain	Lipoxygenase	ALOX12 ALOX15	1.22e-04	6	54	2	PF00305
Domain	LIPOXYGENASE_3	ALOX12 ALOX15	1.22e-04	6	54	2	PS51393
Domain	LIPOXYGENASE_2	ALOX12 ALOX15	1.22e-04	6	54	2	PS00081
Domain	LipOase	ALOX12 ALOX15	1.22e-04	6	54	2	IPR000907
Domain	LipOase_Fe_BS	ALOX12 ALOX15	1.22e-04	6	54	2	IPR020833
Domain	LipOase_CS	ALOX12 ALOX15	1.22e-04	6	54	2	IPR020834
Domain	Ion_trans_dom	KCNA1 KCNA2 KCNA3 KCNA4	3.29e-04	114	54	4	IPR005821
Domain	Ion_trans	KCNA1 KCNA2 KCNA3 KCNA4	3.29e-04	114	54	4	PF00520
Domain	HMG_box	SOX9 SOX10 SOX15	4.83e-04	53	54	3	PF00505
Domain	HMG_BOX_2	SOX9 SOX10 SOX15	5.11e-04	54	54	3	PS50118
Domain	HMG	SOX9 SOX10 SOX15	5.11e-04	54	54	3	SM00398
Domain	-	SOX9 SOX10 SOX15	5.39e-04	55	54	3	1.10.30.10
Domain	HMG_box_dom	SOX9 SOX10 SOX15	8.79e-04	65	54	3	IPR009071
Domain	LH2	ALOX12 ALOX15	1.22e-03	18	54	2	SM00308
Domain	EF-hand-dom_pair	TCHH CABP4 SPEF2 CALML4 PLCD1	1.41e-03	287	54	5	IPR011992
Domain	PLAT	ALOX12 ALOX15	1.66e-03	21	54	2	PS50095
Domain	-	ALOX12 ALOX15	1.66e-03	21	54	2	2.60.60.20
Domain	PLAT	ALOX12 ALOX15	1.66e-03	21	54	2	PF01477
Domain	PLAT/LH2_dom	ALOX12 ALOX15	1.66e-03	21	54	2	IPR001024
Domain	BTB	KCNA1 KCNA2 KCNA3 KCNA4	1.81e-03	180	54	4	SM00225
Domain	BTB/POZ_dom	KCNA1 KCNA2 KCNA3 KCNA4	2.00e-03	185	54	4	IPR000210
Domain	SKP1/BTB/POZ	KCNA1 KCNA2 KCNA3 KCNA4	2.16e-03	189	54	4	IPR011333
Domain	JmjC	PHF2 KDM5A	2.17e-03	24	54	2	PF02373
Domain	JMJC	PHF2 KDM5A	3.85e-03	32	54	2	PS51184
Domain	JmjC_dom	PHF2 KDM5A	3.85e-03	32	54	2	IPR003347
Domain	JmjC	PHF2 KDM5A	4.09e-03	33	54	2	SM00558
Domain	EF_HAND_2	TCHH CABP4 CALML4 PLCD1	4.44e-03	231	54	4	PS50222
Domain	EF_hand_dom	TCHH CABP4 CALML4 PLCD1	4.51e-03	232	54	4	IPR002048
Domain	-	TCHH CABP4 CALML4 PLCD1	6.82e-03	261	54	4	1.10.238.10
Domain	EF-hand_1	TCHH CABP4 PLCD1	9.68e-03	152	54	3	PF00036
Domain	EFh	CABP4 CALML4 PLCD1	1.07e-02	158	54	3	SM00054
Pathway	BIOCARTA_BARRESTIN_PATHWAY	KCNA2 KCNA3 KCNA4	2.94e-06	11	38	3	MM1501
Pathway	BIOCARTA_BARRESTIN_PATHWAY	KCNA1 KCNA2 KCNA3	3.91e-06	12	38	3	M7772
Pathway	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	KCNA1 KCNA2 KCNA3 KCNA4	4.23e-06	41	38	4	MM14546
Pathway	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	KCNA1 KCNA2 KCNA3 KCNA4	5.14e-06	43	38	4	M1056
Pathway	BIOCARTA_BARR_MAPK_PATHWAY	KCNA1 KCNA2 KCNA3	6.44e-06	14	38	3	M668
Pathway	BIOCARTA_BARR_MAPK_PATHWAY	KCNA2 KCNA3 KCNA4	6.44e-06	14	38	3	MM1489
Pathway	BIOCARTA_BARRESTIN_SRC_PATHWAY	KCNA1 KCNA2 KCNA3	1.20e-05	17	38	3	M111
Pathway	BIOCARTA_BARRESTIN_SRC_PATHWAY	KCNA2 KCNA3 KCNA4	1.20e-05	17	38	3	MM1491
Pathway	WP_METABOLISM_OF_ALPHALINOLENIC_ACID	ALOX12 ALOX15	1.05e-04	6	38	2	M39844
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNA1 KCNA2 KCNA3 KCNA4	1.35e-04	98	38	4	MM14545
Pathway	REACTOME_SYNTHESIS_OF_12_EICOSATETRAENOIC_ACID_DERIVATIVES	ALOX12 ALOX15	1.47e-04	7	38	2	M27139
Pathway	REACTOME_SYNTHESIS_OF_12_EICOSATETRAENOIC_ACID_DERIVATIVES	ALOX12 ALOX15	1.47e-04	7	38	2	MM14860
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNA1 KCNA2 KCNA3 KCNA4	1.64e-04	103	38	4	M1073
Pathway	BIOCARTA_AKAPCENTROSOME_PATHWAY	PRKCE PCNT	4.59e-04	12	38	2	MM1460
Pathway	BIOCARTA_AKAPCENTROSOME_PATHWAY	PRKCE PCNT	6.31e-04	14	38	2	M15347
Pathway	BIOCARTA_ETS_PATHWAY	CSF1R HDAC2	9.38e-04	17	38	2	M14449
Pathway	BIOCARTA_ETS_PATHWAY	CSF1R HDAC2	9.38e-04	17	38	2	MM1435
Pathway	REACTOME_BIOSYNTHESIS_OF_SPECIALIZED_PRORESOLVING_MEDIATORS_SPMS	ALOX12 ALOX15	1.18e-03	19	38	2	M27889
Pathway	WP_EICOSANOID_SYNTHESIS	ALOX12 ALOX15	1.58e-03	22	38	2	MM15961
Pathway	REACTOME_BIOSYNTHESIS_OF_SPECIALIZED_PRORESOLVING_MEDIATORS_SPMS	ALOX12 ALOX15	1.58e-03	22	38	2	MM15614
Pathway	WP_EICOSANOID_SYNTHESIS	ALOX12 ALOX15	1.73e-03	23	38	2	M39382
Pubmed	Subunit composition of Kv1 channels in human CNS.	KCNA1 KCNA2 KCNA3 KCNA4	2.79e-11	5	55	4	10428084
Pubmed	Differential K+ channel clustering activity of PSD-95 and SAP97, two related membrane-associated putative guanylate kinases.	KCNA1 KCNA2 KCNA3 KCNA4	8.37e-11	6	55	4	8938729
Pubmed	Truncation of the Shaker-like voltage-gated potassium channel, Kv1.1, causes megencephaly.	KCNA1 KCNA2 KCNA3 KCNA4	8.37e-11	6	55	4	14686897
Pubmed	Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases.	KCNA1 KCNA2 KCNA3 KCNA4	1.95e-10	7	55	4	7477295
Pubmed	N-terminal PDZ-binding domain in Kv1 potassium channels.	KCNA1 KCNA2 KCNA3 KCNA4	3.90e-10	8	55	4	12435606
Pubmed	Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells.	KCNA1 KCNA2 KCNA3 KCNA4	1.17e-09	10	55	4	1383027
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	KCNA1 KCNA2 KCNA3 KCNA4 MDN1 HNRNPUL2 KDM5A SVIL PRKCE ZNF318 ERBIN HDAC2 PCNT	2.57e-09	963	55	13	28671696
Pubmed	Mutations in the KCNA1 gene associated with episodic ataxia type-1 syndrome impair heteromeric voltage-gated K(+) channel function.	KCNA1 KCNA2 KCNA4	3.74e-09	3	55	3	10428758
Pubmed	Human potassium channel genes: Molecular cloning and functional expression.	KCNA1 KCNA2 KCNA4	3.74e-09	3	55	3	19912772
Pubmed	A family of three mouse potassium channel genes with intronless coding regions.	KCNA1 KCNA2 KCNA3	3.74e-09	3	55	3	2305265
Pubmed	Human transcription factor protein interaction networks.	PHF2 SOX9 SOX10 SOX15 PPP2R2A HNRNPUL2 RBM27 KDM5A SMCHD1 SVIL ZNF318 ZNF512 ERBIN HDAC2 EXOC4	3.78e-09	1429	55	15	35140242
Pubmed	KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.	KCNA1 KCNA2 KCNA3	1.50e-08	4	55	3	12944270
Pubmed	K+ current diversity is produced by an extended gene family conserved in Drosophila and mouse.	KCNA1 KCNA2 KCNA3	3.73e-08	5	55	3	2333511
Pubmed	Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow.	KCNA1 KCNA2 KCNA3	3.73e-08	5	55	3	21233214
Pubmed	Physical mapping of potassium channel gene clusters on mouse chromosomes three and six.	KCNA1 KCNA2 KCNA3	7.46e-08	6	55	3	9286706
Pubmed	Chromosomal mapping in the mouse of eight K(+)-channel genes representing the four Shaker-like subfamilies Shaker, Shab, Shaw, and Shal.	KCNA1 KCNA2 KCNA3 KCNA4	8.15e-08	26	55	4	7905852
Pubmed	Pore size matters for potassium channel conductance.	KCNA1 KCNA2 KCNA4	1.30e-07	7	55	3	27619418
Pubmed	Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2.	KCNA1 KCNA2 KCNA4	1.30e-07	7	55	3	18509034
Pubmed	Heteromultimeric delayed-rectifier K+ channels in schwann cells: developmental expression and role in cell proliferation.	KCNA1 KCNA2 KCNA4	1.30e-07	7	55	3	9852577
Pubmed	Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7.	KCNA1 KCNA2 KCNA3	3.12e-07	9	55	3	9488722
Pubmed	International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.	KCNA1 KCNA2 KCNA3 KCNA4	4.90e-07	40	55	4	16382104
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	PHF2 RBM27 SMCHD1 SMC6 ZNF512 ERBIN MED13 EXOC4 PCNT	7.30e-07	645	55	9	25281560
Pubmed	HDAC1 and HDAC2 control the specification of neural crest cells into peripheral glia.	SOX9 SOX10 HDAC2	1.06e-06	13	55	3	24760871
Pubmed	Numerous members of the Sox family of HMG box-containing genes are expressed in developing mouse teeth.	SOX9 SOX10 SOX15	1.35e-06	14	55	3	8921394
Pubmed	Differential isoform expression and alternative splicing in sex determination in mice.	SOX9 SOX10 SOX15	1.68e-06	15	55	3	30871468
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	SOX9 SOX10 KCNA2 KCNA3 KCNA4 CABP4 PRKCE CALML4 HDAC2	2.02e-06	730	55	9	34857952
Pubmed	Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness.	KCNA1 KCNA2 KCNA3	2.07e-06	16	55	3	28283561
Pubmed	Emerging role of 12/15-Lipoxygenase (ALOX15) in human pathologies.	ALOX12 ALOX15	2.46e-06	2	55	2	30472260
Pubmed	Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway.	ALOX12 ALOX15	2.46e-06	2	55	2	19373248
Pubmed	Platelet-type 12-lipoxygenase deletion provokes a compensatory 12/15-lipoxygenase increase that exacerbates oxidative stress in mouse islet β cells.	ALOX12 ALOX15	2.46e-06	2	55	2	30792307
Pubmed	Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis.	ALOX12 ALOX15	2.46e-06	2	55	2	25251155
Pubmed	A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense.	ALOX12 ALOX15	2.46e-06	2	55	2	15708862
Pubmed	Moving gating charges through the gating pore in a Kv channel voltage sensor.	KCNA1 KCNA2	2.46e-06	2	55	2	24782544
Pubmed	De novo KCNA1 variants in the PVP motif cause infantile epileptic encephalopathy and cognitive impairment similar to recurrent KCNA2 variants.	KCNA1 KCNA2	2.46e-06	2	55	2	30055040
Pubmed	Role of Src tyrosine kinase in the atherogenic effects of the 12/15-lipoxygenase pathway in vascular smooth muscle cells.	ALOX12 ALOX15	2.46e-06	2	55	2	19095999
Pubmed	Differential expression and localization of 12/15 lipoxygenases in adipose tissue in human obese subjects.	ALOX12 ALOX15	2.46e-06	2	55	2	21094135
Pubmed	Kv1.1 and Kv1.2: similar channels, different seizure models.	KCNA1 KCNA2	2.46e-06	2	55	2	22612818
Pubmed	Enhancement role of host 12/15-lipoxygenase in melanoma progression.	ALOX12 ALOX15	2.46e-06	2	55	2	23664097
Pubmed	Association of the Kv1 family of K+ channels and their functional blueprint in the properties of auditory neurons as revealed by genetic and functional analyses.	KCNA1 KCNA2	2.46e-06	2	55	2	23864368
Pubmed	Lipoxygenase metabolites are mediators of PTH-dependent human osteoblast growth.	ALOX12 ALOX15	2.46e-06	2	55	2	18187376
Pubmed	Expression and chromosomal localization of a lymphocyte K+ channel gene.	KCNA2 KCNA3	2.46e-06	2	55	2	2251283
Pubmed	EGF stimulates lipoxin A4 synthesis and modulates repair in corneal epithelial cells through ERK and p38 activation.	ALOX12 ALOX15	2.46e-06	2	55	2	21220563
Pubmed	12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma.	ALOX12 ALOX15	2.46e-06	2	55	2	23528921
Pubmed	Co-expression of SOX9 and SOX10 during melanocytic differentiation in vitro.	SOX9 SOX10	2.46e-06	2	55	2	15896776
Pubmed	AKT-mediated phosphorylation of Sox9 induces Sox10 transcription in a murine model of HER2-positive breast cancer.	SOX9 SOX10	2.46e-06	2	55	2	33985544
Pubmed	Polymorphisms in the human ALOX12 and ALOX15 genes are associated with peak bone mineral density in Chinese nuclear families.	ALOX12 ALOX15	2.46e-06	2	55	2	22089472
Pubmed	Alox12/15 Deficiency Exacerbates, While Lipoxin A4 Ameliorates Hepatic Inflammation in Murine Alcoholic Hepatitis.	ALOX12 ALOX15	2.46e-06	2	55	2	32760397
Pubmed	Arachidonate 12/15-lipoxygenase-induced inflammation and oxidative stress are involved in the development of diabetic cardiomyopathy.	ALOX12 ALOX15	2.46e-06	2	55	2	25187369
Pubmed	12/15-Lipoxygenase signaling in the endoplasmic reticulum stress response.	ALOX12 ALOX15	2.46e-06	2	55	2	22215650
Pubmed	Functional role of Kv1.1 and Kv1.3 channels in the neoplastic progression steps of three cancer cell lines, elucidated by scorpion peptides.	KCNA1 KCNA3	2.46e-06	2	55	2	29415410
Pubmed	12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice.	ALOX12 ALOX15	2.46e-06	2	55	2	19787041
Pubmed	Isotope sensitive branching and kinetic isotope effects in the reaction of deuterated arachidonic acids with human 12- and 15-lipoxygenases.	ALOX12 ALOX15	2.46e-06	2	55	2	18547056
Pubmed	Disinactivation of N-type inactivation of voltage-gated K channels by an erbstatin analogue.	KCNA1 KCNA4	2.46e-06	2	55	2	15136567
Pubmed	12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet.	ALOX12 ALOX15	2.46e-06	2	55	2	18780776
Pubmed	Mechanistic investigations of human reticulocyte 15- and platelet 12-lipoxygenases with arachidonic acid.	ALOX12 ALOX15	2.46e-06	2	55	2	19469483
Pubmed	Episodic ataxia type 1 mutations affect fast inactivation of K+ channels by a reduction in either subunit surface expression or affinity for inactivation domain.	KCNA1 KCNA4	2.46e-06	2	55	2	21307345
Pubmed	The evolutionary hypothesis of reaction specificity of mammalian ALOX15 orthologs.	ALOX12 ALOX15	2.46e-06	2	55	2	30237084
Pubmed	12/15-lipoxygenase is increased in Alzheimer's disease: possible involvement in brain oxidative stress.	ALOX12 ALOX15	2.46e-06	2	55	2	15111312
Pubmed	Polymorphisms in ALOX12, but not ALOX15, are significantly associated with BMD in postmenopausal women.	ALOX12 ALOX15	2.46e-06	2	55	2	17520163
Pubmed	Human ALOX12, but not ALOX15, is associated with BMD in white men and women.	ALOX12 ALOX15	2.46e-06	2	55	2	16598376
Pubmed	Expression of 12/15-lipoxygenase attenuates intracellular lipid deposition during in vitro foam cell formation.	ALOX12 ALOX15	2.46e-06	2	55	2	15681297
Pubmed	Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma.	SOX9 SOX10	2.46e-06	2	55	2	25629959
Pubmed	Amelioration of the Alzheimer's disease phenotype by absence of 12/15-lipoxygenase.	ALOX12 ALOX15	2.46e-06	2	55	2	20570249
Pubmed	Biosynthesis of the Maresin Intermediate, 13S,14S-Epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and Its Regulation through Negative Allosteric Modulators.	ALOX12 ALOX15	2.46e-06	2	55	2	32324389
Pubmed	Localization of Kv1.1 and Kv1.2, two K channel proteins, to synaptic terminals, somata, and dendrites in the mouse brain.	KCNA1 KCNA2	2.46e-06	2	55	2	8046438
Pubmed	A C-terminally amidated analogue of ShK is a potent and selective blocker of the voltage-gated potassium channel Kv1.3.	KCNA1 KCNA3	2.46e-06	2	55	2	23063513
Pubmed	Reactive oxygen species and 12/15-lipoxygenase contribute to the antiproliferative capacity of alternatively activated myeloid cells elicited during helminth infection.	ALOX12 ALOX15	2.46e-06	2	55	2	15879104
Pubmed	An epilepsy-associated KV1.2 charge-transfer-center mutation impairs KV1.2 and KV1.4 trafficking.	KCNA2 KCNA4	2.46e-06	2	55	2	35439054
Pubmed	Sound Localization in Preweanling Mice Was More Severely Affected by Deleting the Kcna1 Gene Compared to Deleting Kcna2, and a Curious Inverted-U Course of Development That Appeared to Exceed Adult Performance Was Observed in All Groups.	KCNA1 KCNA2	2.46e-06	2	55	2	31410614
Pubmed	Expression of SOX9 and SOX10 in central neuroepithelial tumor.	SOX9 SOX10	2.46e-06	2	55	2	16791471
Pubmed	Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis.	ALOX12 ALOX15	2.46e-06	2	55	2	29184033
Pubmed	Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice.	ALOX12 ALOX15	2.46e-06	2	55	2	10330425
Pubmed	Reciprocal regulation of 12- and 15-lipoxygenases by UV-irradiation in human keratinocytes.	ALOX12 ALOX15	2.46e-06	2	55	2	18755188
Pubmed	12-Lipoxygenase isoenzymes in mouse skin tumor development.	ALOX12 ALOX15	2.46e-06	2	55	2	7576099
Pubmed	Expression and localization of Kv1 potassium channels in rat dorsal and ventral spinal roots.	KCNA1 KCNA2	2.46e-06	2	55	2	18053989
Pubmed	Gradual decorrelation of CA3 ensembles associated with contextual discrimination learning is impaired by Kv1.2 insufficiency.	KCNA1 KCNA2	2.46e-06	2	55	2	34964210
Pubmed	Voltage-gated delayed rectifier K v 1-subunits may serve as distinctive markers for enteroglial cells with different phenotypes in the murine ileum.	KCNA1 KCNA2	2.46e-06	2	55	2	19549557
Pubmed	The 12/15-lipoxygenase as an emerging therapeutic target for Alzheimer's disease.	ALOX12 ALOX15	2.46e-06	2	55	2	25708815
Pubmed	Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction.	ALOX12 ALOX15	2.46e-06	2	55	2	25293588
Pubmed	Kinetic investigations of the rate-limiting step in human 12- and 15-lipoxygenase.	ALOX12 ALOX15	2.46e-06	2	55	2	12731864
Pubmed	The 12/15-lipoxygenase pathway counteracts fibroblast activation and experimental fibrosis.	ALOX12 ALOX15	2.46e-06	2	55	2	22267335
Pubmed	Lack of association of ALOX12 and ALOX15 polymorphisms with aspirin-exacerbated respiratory disease in Korean patients.	ALOX12 ALOX15	2.46e-06	2	55	2	19663136
Pubmed	12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis.	ALOX12 ALOX15	2.46e-06	2	55	2	19675173
Pubmed	Overexpression of 12/15-lipoxygenase increases anxiety behavior in female mice.	ALOX12 ALOX15	2.46e-06	2	55	2	24300237
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	KCNA1 KCNA2 KCNA3 KCNA4 PRKCE ERBIN	2.87e-06	251	55	6	27507650
Pubmed	Expression of Sox transcription factors in the developing mouse pancreas.	SOX9 SOX10 SOX15	4.88e-06	21	55	3	12815626
Pubmed	The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas.	SOX9 SOX10 SOX15	4.88e-06	21	55	3	16306355
Pubmed	The functional interactome landscape of the human histone deacetylase family.	PPP2R2A MDN1 KDM5A RBM12B SVIL HDAC2	6.44e-06	289	55	6	23752268
Pubmed	Human 5-, 12- and 15-lipoxygenase-1 coexist in kidney but show opposite trends and their balance changes in cancer.	ALOX12 ALOX15	7.36e-06	3	55	2	22825379
Pubmed	5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy.	ALOX12 ALOX15	7.36e-06	3	55	2	18346986
Pubmed	Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis.	ALOX12 ALOX15	7.36e-06	3	55	2	22279185
Pubmed	Subunit composition and novel localization of K+ channels in spinal cord.	KCNA1 KCNA2	7.36e-06	3	55	2	11086297
Pubmed	Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase.	ALOX12 ALOX15	7.36e-06	3	55	2	15328042
Pubmed	Improved survival and reduced vascular permeability by eliminating or blocking 12/15-lipoxygenase in mouse models of acute lung injury (ALI).	ALOX12 ALOX15	7.36e-06	3	55	2	19752233
Pubmed	Smooth muscle-specific expression of calcium-independent phospholipase A2β (iPLA2β) participates in the initiation and early progression of vascular inflammation and neointima formation.	ALOX12 ALOX15	7.36e-06	3	55	2	22637477
Pubmed	Transcriptional regulation of β-secretase-1 by 12/15-lipoxygenase results in enhanced amyloidogenesis and cognitive impairments.	ALOX12 ALOX15	7.36e-06	3	55	2	22275252
Pubmed	Role of 12/15-lipoxygenase in the expression of MCP-1 in mouse macrophages.	ALOX12 ALOX15	7.36e-06	3	55	2	18296557
Pubmed	Relationship between 12/15-lipoxygenase and COX-2 in mesangial cells: potential role in diabetic nephropathy.	ALOX12 ALOX15	7.36e-06	3	55	2	16514433
Pubmed	Differential expression of epithelial–mesenchymal transition and stem cell markers in intrinsic subtypes of breast cancer.	SOX9 SOX10	7.36e-06	3	55	2	26467042
Pubmed	Following experimental stroke, the recovering brain is vulnerable to lipoxygenase-dependent semaphorin signaling.	ALOX12 ALOX15	7.36e-06	3	55	2	23070608
Interaction	KCNA4 interactions	KCNA1 KCNA2 KCNA3 KCNA4 ERBIN	1.15e-06	68	55	5	int:KCNA4
Interaction	KCNA1 interactions	KCNA1 KCNA2 KCNA3 KCNA4	2.44e-06	35	55	4	int:KCNA1
Interaction	NR3C1 interactions	WDR19 MDN1 KDM5A PPM1F SMCHD1 SVIL KIF16B APOL6 BRCC3 ZNF512 LMOD2 HDAC2	9.71e-06	974	55	12	int:NR3C1
Interaction	KCNA5 interactions	KCNA2 KCNA3 KCNA4 ERBIN	2.16e-05	60	55	4	int:KCNA5
Cytoband	5q32	CSF1R RBM27 ARHGEF37	3.86e-05	54	55	3	5q32
Cytoband	Ensembl 112 genes in cytogenetic band chr5q32	CSF1R RBM27 ARHGEF37	1.25e-04	80	55	3	chr5q32
GeneFamily	Potassium voltage-gated channels	KCNA1 KCNA2 KCNA3 KCNA4	2.87e-06	40	45	4	274
GeneFamily	SRY-boxes	SOX9 SOX10 SOX15	1.36e-05	19	45	3	757
GeneFamily	Arachidonate lipoxygenases	ALOX12 ALOX15	9.03e-05	6	45	2	407
GeneFamily	Histone deacetylases, class I\|EMSY complex\|NuRD complex\|SIN3 histone deacetylase complex	KDM5A HDAC2	3.94e-04	12	45	2	1243
GeneFamily	PHD finger proteins\|Lysine demethylases	PHF2 KDM5A	1.61e-03	24	45	2	485
GeneFamily	EF-hand domain containing	TCHH CABP4 CALML4 PLCD1	2.12e-03	219	45	4	863
Coexpression	GSE3920_UNTREATED_VS_IFNB_TREATED_ENDOTHELIAL_CELL_UP	ANKRD13A CSF1R KDM5A SVIL ALOX12 PCNT	3.89e-06	200	55	6	M6686
Coexpression	GSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN	PHF2 PPP2R2A RBM27 SVIL ZNF318	2.66e-05	167	55	5	M361
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX10 KCNA1 KCNA2 SPEF2 CASR	1.82e-06	164	55	5	3caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX10 KCNA1 KCNA2 PPP1R1B ARHGEF37	2.50e-06	175	55	5	bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCell	droplet-Bladder-nan-24m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNA1 KCNA2 EPYC PPP1R1B ALOX15	2.79e-06	179	55	5	dfd9d29281510d32f1a2e8336d2e58ef496cfd1d
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 SOX15 KCNA1 KCNA2 ALOX15	3.11e-06	183	55	5	4de2082dca2569d3aac3c9b466f27971c82d302b
ToppCell	droplet-Heart-4Chambers-21m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 SOX15 KCNA1 KCNA2 ALOX15	3.11e-06	183	55	5	a046b569bc10083d471b420eb2c6fee93437602d
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 RBM12B PPP1R1B ARHGEF37	3.28e-06	185	55	5	554c5d812197fbf66bf279fcc953277e926ade15
ToppCell	Entopeduncular-Macroglia-POLYDENDROCYTE\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SOX10 PPP2R2A LAD1 CASR	3.19e-05	146	55	4	a317f14a1aab11ffcce65baeb1c475c04324315f
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CD247 KCNA3 RBM27 APOL6	3.83e-05	153	55	4	d8773ee16c7d3e0834b9f64054d42336d6f9833b
ToppCell	ICU-SEP-Myeloid-cDC1\|ICU-SEP / Disease, Lineage and Cell Type	KIF16B ZNF318 PLCD1 ALOX15	4.67e-05	161	55	4	9fb73909fc2ec99f96ca2eed1a053bce89de7d16
ToppCell	Club-club-12\|World / Class top	CRACD PPP1R1B FAM186B ALOX15	5.14e-05	165	55	4	9b7a31cbdcd2f96b8bd08a4cd4141b92bd5e9062
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX10 KCNA2 KCNA4 ALOX15	5.64e-05	169	55	4	2456b3e7776e8a2214972be1b4d66a3ca5480ae0
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SOX9 EPYC PPP1R1B PLCD1	5.64e-05	169	55	4	58e22f9119240664515fe91ca53812611a8f17d6
ToppCell	droplet-Spleen-nan-21m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 CSF1R ARHGEF37 ALOX15	5.77e-05	170	55	4	03cb4e508356f85372a588c8d1c6babf2a012683
ToppCell	droplet-Spleen-nan-21m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 CSF1R ARHGEF37 ALOX15	5.91e-05	171	55	4	9498c35b2a2c3a339dc8c5d49c8ec20d8ad52753
ToppCell	droplet-Spleen-nan-21m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 CSF1R ARHGEF37 ALOX15	5.91e-05	171	55	4	db544252f98e073e5bb4bec4a110cd58e6434435
ToppCell	droplet-Liver-nan-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNA2 CSF1R KIF16B APOL6	6.04e-05	172	55	4	1f335ccb92b22d0412954e8fc3af212f96410b67
ToppCell	droplet-Liver-nan-3m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNA2 CSF1R KIF16B APOL6	6.04e-05	172	55	4	bb96c896d125e10b71e94e2bdad243899045af5c
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD KCNA2 ALOX15 CUEDC1	6.46e-05	175	55	4	1b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD KCNA2 ALOX15 CUEDC1	6.46e-05	175	55	4	a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Syt6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CABP4 GYS2 APOL6	6.52e-05	63	55	3	d0cb6178fc789577be29040ed77bf8dd5e1e4cd5
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Cplx3_(Cortical_Subplate_pyramidal_cells)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CABP4 GYS2 APOL6	6.52e-05	63	55	3	865351818efde53e9e130f526a8e4797b3d01efb
ToppCell	wk_08-11-Mesenchymal-Chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SOX9 KCNA1 KCNA3 EPYC	6.60e-05	176	55	4	1af28b701c4598ce761f85adbd5d79e4918d265a
ToppCell	P15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SOX10 CRACD KCNA1 KCNA2	6.60e-05	176	55	4	792f414f5092aba14260b8e16378e793a822498e
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX10 KCNA1 KCNA2 PPP1R1B	6.75e-05	177	55	4	59cf56c385c324f0844f20003d2b5049a2791e45
ToppCell	droplet-Limb_Muscle-nan-24m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 ALOX12	6.90e-05	178	55	4	f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYT1L ANO2 KCNA4 PPP1R1B	7.05e-05	179	55	4	a3922476f33d2e4137a12dbda21a1703dff79684
ToppCell	wk_08-11-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SOX9 TCHH KCNA1 EPYC	7.52e-05	182	55	4	0e52ba34e179d9bfaac7b49920b44c710b2b8dad
ToppCell	IIH-Treg-proli_CD4\|IIH / Condition, Cell_class and T cell subcluster	PHF2 PLCD1 ZSCAN16 ERBIN	7.52e-05	182	55	4	5c7d02da9ca2bca49db9832704b6894dfaa08a71
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX10 KCNA1 KCNA2 ARHGEF37	7.52e-05	182	55	4	a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	7.52e-05	182	55	4	82ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCell	droplet-Heart-nan-18m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	7.68e-05	183	55	4	1701c8c212f1fdb6e4764375542a203e19753d14
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	7.68e-05	183	55	4	2cf36ad89584eb9f8b04de52a1b511b7f3527884
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	7.68e-05	183	55	4	98fee6838acfaee5e2e449ba088764ec06b8bc57
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	7.85e-05	184	55	4	da8d6e7944eb35e6cbea2feb7cbc2894787d723f
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 ALOX12	7.85e-05	184	55	4	e33bb572af9dfd11127105f1ac99bc958a7cafbb
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	7.85e-05	184	55	4	9f8cd5ab5af6c35a1be25d70a125b9a3f4dd667a
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 CRACD KCNA1 PPP1R1B	8.01e-05	185	55	4	11c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD PPP1R1B LAD1 LMOD2	8.01e-05	185	55	4	9ef66bf63ed728cbf3044520a2a1625a9d5863a4
ToppCell	droplet-Heart-nan-18m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	8.01e-05	185	55	4	c61267cfadea018794f7964904445787629a40d1
ToppCell	droplet-Heart-nan-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	8.01e-05	185	55	4	3a592719d5643011954f89d5bb61a5e94682b68e
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD PPP1R1B LAD1 LMOD2	8.01e-05	185	55	4	2148b78db2afaf29b01d604d314d6061179e2663
ToppCell	droplet-Lung-LUNG-1m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 CRACD KCNA1 PPP1R1B	8.18e-05	186	55	4	e52cf44989c57c433bf82e9fa13b4643e88f3577
ToppCell	droplet-Lung-LUNG-1m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 CRACD KCNA1 PPP1R1B	8.18e-05	186	55	4	4c0b59d845b79323e7a3287e7c4d249f5f322556
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	8.18e-05	186	55	4	d8d559daff4aeef334d403fde4e3ee2e4a6086d0
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 ALOX15	8.18e-05	186	55	4	ea936e66ae4b7b40564711fad60ac0137327995f
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	CRACD SMCHD1 KIF16B ERBIN	8.18e-05	186	55	4	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	8.35e-05	187	55	4	16e55d802fc4e71878305e61ad03806aabd59537
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX10 KCNA1 KCNA2 PPP1R1B	8.35e-05	187	55	4	6f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX10 KCNA1 KCNA2 PPP1R1B	8.35e-05	187	55	4	8e8b147258982b359447add5027318f5b6d51963
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	8.52e-05	188	55	4	8385fd384fc55e3b17802bb6698eb93b2c16d7f2
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD KCNA4 LAD1 LMOD2	8.52e-05	188	55	4	90dc0e15798d0b984518ad58c7e416e30aff687a
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	8.52e-05	188	55	4	c2101ded71fb16b8ddbc1f883911b1ed2a533ffc
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	8.52e-05	188	55	4	3b8b9161f0fdcbde302ce5b4c0bc874628211109
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD KCNA4 LAD1 LMOD2	8.52e-05	188	55	4	f63dfd076ced81013918363282ae25cbbd8948ae
ToppCell	facs-Heart-LA/RA-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD KCNA4 LAD1 LMOD2	8.52e-05	188	55	4	0554d542149cef654ff1e5e32dfbffd8990b52bd
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	8.52e-05	188	55	4	cb9d0b48e2fd9cc576132803273b9c0382900944
ToppCell	facs-Heart-LA/RA-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD KCNA4 LAD1 LMOD2	8.70e-05	189	55	4	a08b2d0fa35ffa510050ecffdc68e1b79bbe1632
ToppCell	facs-Heart-LA/RA\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRACD KCNA4 LAD1 LMOD2	8.70e-05	189	55	4	efa913d9c16fc32166b484d92b6449e8a0c59e03
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	8.88e-05	190	55	4	e2481bd5166fde2cdc0c3824894f2bccb8294fdd
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	8.88e-05	190	55	4	ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 KCNA1 KCNA2 PPP1R1B	8.88e-05	190	55	4	4971857eac9af17d66d673ed2ab7072639f60a10
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_progenitor_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX9 SOX10 LAD1 ALOX15	9.62e-05	194	55	4	0ef63abcfd057079a9a6f8b27404ff521d44845d
ToppCell	(3)_Chondrocytes-(34)_Chondro-progen\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	SOX9 CRACD PPP1R1B CASR	9.82e-05	195	55	4	d00cb2fab25f2026a9668a7f0686938a2e7155e2
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TCHH PPP1R1B CASR CALML4	1.02e-04	197	55	4	1ffbbe44db0fd3ebd91ad16ab0b91153de5d7c6d
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_basal-Suprabasal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SOX15 LAD1 CALML4 ALOX15	1.08e-04	200	55	4	5f0f67958c9635db53e61f8370a92da6ea3e80fe
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	MYT1L CRACD KCNA3 PRKCE	1.08e-04	200	55	4	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	mild-B_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMCHD1 SMC6 PRKCE ZNF318	1.08e-04	200	55	4	222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ANO2 EPYC PPP1R1B	1.19e-04	77	55	3	10969743351c49a1d6d8ae1ef93098e7786ca3fe
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ANO2 EPYC APOL6	1.19e-04	77	55	3	a799ccdb84014e978d9fbccf3d2fee8fbeac7b0c
ToppCell	PBMC-Severe-cDC_1\|Severe / Compartment, Disease Groups and Clusters	PHF2 CD247 APOL6	1.38e-04	81	55	3	6d1e524f000b71c935359afc801a1d31f218fec8
ToppCell	(04)_Pre-ciliated-(4)_1wkpi\|(04)_Pre-ciliated / shred by cell type and Timepoint	MYT1L PDZD7 ALOX15	1.82e-04	89	55	3	846c2fec66981bf41be64a2e1812ec1b1b833961
Drug	LY97241	KCNA1 KCNA2 KCNA4	1.11e-06	9	55	3	CID000175064
Drug	AC1L1B9H	KCNA1 KCNA2 KCNA3 KCNA4 PRKCE	1.26e-06	78	55	5	CID000001341
Drug	eicosa-11,14-dienoic acid	PRKCE ALOX12 ALOX15	1.58e-06	10	55	3	CID000003208
Drug	doyle	KCNA1 KCNA2 KCNA3 KCNA4 PLCD1	2.30e-06	88	55	5	CID000002245
Drug	Psora-4	KCNA1 KCNA2 KCNA4	3.75e-06	13	55	3	CID006603977
Drug	digitoxigenine	KCNA1 KCNA2 KCNA3 KCNA4	7.00e-06	51	55	4	CID000008932
Drug	tetrapentylammonium	KCNA1 KCNA2 KCNA4	8.86e-06	17	55	3	CID000017248
Drug	fullerene C60	WDR19 ANKRD13A TBKBP1 CSF1R PPM1F GYS2 PRKCE BRCC3 PDZD7 ARHGEF37 MED13 ALOX15 HDAC2 CUEDC1	9.05e-06	1498	55	14	ctd:C069837
Drug	Inositol Phosphates	PRKCE CASR PLCD1	1.48e-05	20	55	3	ctd:D007295
Drug	KC8851	KCNA2 KCNA4	1.72e-05	3	55	2	CID000065956
Drug	AC1Q1NVI	KCNA2 KCNA3	1.72e-05	3	55	2	CID006439529
Drug	13(R)-hydroxy-octadeca-(9Z,11E,15Z)-trienoic acid	ALOX12 ALOX15	1.72e-05	3	55	2	CID000643726
Drug	N-arachidonoylethanolamine	KCNA1 KCNA2 KCNA4 PRKCE ALOX12 ALOX15	1.73e-05	226	55	6	CID000002185
Drug	AC1L1O6Q	KCNA3 KCNA4 CSF1R PRKCE PLCD1	2.30e-05	141	55	5	CID000058035
Drug	clofilium	KCNA1 KCNA2 KCNA3 KCNA4	3.09e-05	74	55	4	CID000002798
Drug	pentylhydrazine	ALOX12 ALOX15	3.43e-05	4	55	2	CID000014246
Drug	AC1NSP79	ALOX12 ALOX15	3.43e-05	4	55	2	CID005313497
Drug	T-22083	ALOX12 ALOX15	3.43e-05	4	55	2	CID006439700
Drug	AC1NR0V5	ALOX12 ALOX15	3.43e-05	4	55	2	CID005282813
Drug	glibenclamide	KCNA1 KCNA2 KCNA3 GYS2 LAD1 APOL6 PRKCE	3.59e-05	382	55	7	CID000003488
Drug	bendiocarb	KCNA1 KCNA2 KCNA4	4.19e-05	28	55	3	CID000002314
Drug	amiodarone	KCNA1 KCNA2 KCNA3 KCNA4 PLCD1	4.22e-05	160	55	5	CID000002156
Drug	trans-permethrin	SOX10 KCNA1 KCNA2 KCNA3	5.59e-05	86	55	4	CID000040159
Drug	14-hydroxydocosahexaenoic acid	ALOX12 ALOX15	5.70e-05	5	55	2	CID006439735
Drug	N-(3-phenoxycinnamyl)acetohydroxamic acid	ALOX12 ALOX15	5.70e-05	5	55	2	ctd:C056614
Drug	artonin E	ALOX12 ALOX15	5.70e-05	5	55	2	CID005481962
Drug	AC1L2VAC	ALOX12 ALOX15	5.70e-05	5	55	2	CID000129261
Drug	5,8-diethoxypsoralen	KCNA2 KCNA3	5.70e-05	5	55	2	CID000656729
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	PHF2 LAD1 CALML4 ERBIN PCNT	6.63e-05	176	55	5	6980_DN
Drug	NSC618487	KCNA1 KCNA2 KCNA3 KCNA4 GYS2 PRKCE BRCC3 PLCD1 ALOX12 ALOX15	6.96e-05	933	55	10	CID000005279
Drug	gallamine	KCNA1 KCNA2 KCNA3	8.26e-05	35	55	3	CID000003450
Drug	AC1L571W	ALOX12 ALOX15	8.54e-05	6	55	2	CID000171201
Drug	CID10948590	KCNA1 KCNA2	8.54e-05	6	55	2	CID010948590
Drug	colnelenic acid	ALOX12 ALOX15	8.54e-05	6	55	2	CID006441679
Drug	isamoxole	ALOX12 ALOX15	8.54e-05	6	55	2	CID000042118
Drug	1-oleoyl-2-DHA-PC	ALOX12 ALOX15	8.54e-05	6	55	2	CID006438829
Drug	CPHU	ALOX12 ALOX15	8.54e-05	6	55	2	CID000124471
Drug	BW A797C	ALOX12 ALOX15	8.54e-05	6	55	2	CID006439067
Drug	AC1MQ2IQ	ALOX12 ALOX15	8.54e-05	6	55	2	CID003394960
Drug	DB04103	KCNA1 KCNA2 ALOX12 ALOX15	8.94e-05	97	55	4	CID004469987
Drug	prostaglandin F2	PHF2 GYS2 PRKCE PLCD1 ALOX12 ALOX15	9.35e-05	306	55	6	CID000000160
Drug	Chlorpheniramine maleate [113-92-8]; Down 200; 10.2uM; PC3; HT_HG-U133A	LAD1 ZNF318 PLCD1 ZSCAN16 CUEDC1	9.76e-05	191	55	5	2055_DN
Drug	reduced haloperidol	KCNA1 KCNA2 KCNA4	9.78e-05	37	55	3	CID000119265
Drug	Heptaminol hydrochloride [543-15-7]; Up 200; 22uM; MCF7; HT_HG-U133A	PHF2 TBKBP1 HNRNPUL2 PLCD1 CUEDC1	1.03e-04	193	55	5	1703_UP
Drug	Pridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; MCF7; HT_HG-U133A	SOX9 KCNA3 HNRNPUL2 PPM1F PRKCE	1.08e-04	195	55	5	3456_UP
Drug	Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; HL60; HT_HG-U133A	SOX15 ANO2 TBKBP1 HNRNPUL2 PLCD1	1.10e-04	196	55	5	2726_UP
Drug	Fluoxetine hydrochloride [59333-67-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A	SOX9 SOX10 KDM5A PRKCE ALOX15	1.10e-04	196	55	5	3314_UP
Drug	AC1NPPZW	KCNA1 KCNA2 KCNA3 KCNA4	1.13e-04	103	55	4	CID005183170
Drug	rofecoxib; Down 200; 10uM; MCF7; HG-U133A	PPM1F SVIL PDZD7 CALML4 PLCD1	1.16e-04	198	55	5	205_DN
Drug	Sulfaphenazole [526-08-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A	SOX9 CSF1R ZNF318 PLCD1 ALOX15	1.16e-04	198	55	5	5507_UP
Drug	Lisuride (S)(-) [18016-80-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	TCHH CSF1R PPM1F PLCD1 ALOX15	1.16e-04	198	55	5	5028_DN
Drug	Zomepirac sodium salt [64092-48-4]; Up 200; 12.8uM; MCF7; HT_HG-U133A	SOX9 TBKBP1 CSF1R KDM5A PRKCE	1.18e-04	199	55	5	6815_UP
Drug	RvD1	ALOX12 ALOX15	1.19e-04	7	55	2	CID016061135
Drug	12-IODE	ALOX12 ALOX15	1.19e-04	7	55	2	CID006450050
Drug	lupenone	ALOX12 ALOX15	1.19e-04	7	55	2	CID000092158
Drug	dicranin	ALOX12 ALOX15	1.19e-04	7	55	2	CID006441084
Drug	Bay 08276	ALOX12 ALOX15	1.19e-04	7	55	2	CID000134943
Drug	tda-1	SOX9 SOX10	1.19e-04	7	55	2	CID000112414
Drug	LS-63783	SOX9 KCNA1 KCNA2 KCNA4 GYS2 PRKCE PLCD1 ALOX12 ALOX15	1.21e-04	804	55	9	CID000000231
Drug	sevoflurane	KCNA1 KCNA2 PRKCE PLCD1	1.22e-04	105	55	4	CID000005206
Drug	desflurane	KCNA1 KCNA2 PRKCE	1.24e-04	40	55	3	CID000042113
Drug	pyraclofos	KCNA1 KCNA2 KCNA3 KCNA4	1.26e-04	106	55	4	CID000093460
Drug	acetazolamide	KCNA1 KCNA2 KCNA3 KCNA4	1.31e-04	107	55	4	CID000001986
Drug	benoxaprofen	APOL6 ALOX12 ALOX15	1.33e-04	41	55	3	CID000039941
Drug	balofloxacin	KCNA1 KCNA2 CSF1R	1.43e-04	42	55	3	CID000065958
Drug	RHC 80267	PRKCE PLCD1 ALOX12 ALOX15	1.56e-04	112	55	4	CID000005063
Drug	Prifelone	ALOX12 ALOX15	1.59e-04	8	55	2	CID000071751
Drug	colneleic acid	ALOX12 ALOX15	1.59e-04	8	55	2	CID006441681
Drug	Cgs 22745	ALOX12 ALOX15	1.59e-04	8	55	2	CID006439321
Drug	TEI-8005	ALOX12 ALOX15	1.59e-04	8	55	2	CID006438655
Drug	htyA	ALOX12 ALOX15	1.59e-04	8	55	2	CID000152267
Drug	CDNQ	ALOX12 ALOX15	1.59e-04	8	55	2	CID000126468
Drug	CBS-113 A	ALOX12 ALOX15	1.59e-04	8	55	2	CID000163834
Drug	Alstonine hydrochloride	KCNA1 KCNA2 HNRNPUL2 CASR	1.79e-04	116	55	4	CID000023039
Drug	AC1Q646P	KCNA1 KCNA2 KCNA3	2.01e-04	47	55	3	CID000005673
Drug	14,15-leukotriene A4	ALOX12 ALOX15	2.04e-04	9	55	2	CID006439604
Drug	octadeca-9,12-dien-1-ol	ALOX12 ALOX15	2.04e-04	9	55	2	CID000068168
Drug	U-56467	ALOX12 ALOX15	2.04e-04	9	55	2	CID006439532
Drug	8,15-diHPETE	ALOX12 ALOX15	2.04e-04	9	55	2	CID005283181
Drug	T 0757	ALOX12 ALOX15	2.04e-04	9	55	2	CID006439291
Drug	13-hydroxylinoleic acid	ALOX12 ALOX15	2.04e-04	9	55	2	CID006438633
Drug	AC1NSXHC	ALOX12 ALOX15	2.04e-04	9	55	2	CID005371969
Drug	U-66,855	ALOX12 ALOX15	2.04e-04	9	55	2	CID000127235
Drug	ODYA	ALOX12 ALOX15	2.04e-04	9	55	2	CID000001931
Drug	A-78773	ALOX12 ALOX15	2.04e-04	9	55	2	CID000071460
Drug	S 19812	ALOX12 ALOX15	2.04e-04	9	55	2	CID005744460
Drug	diazoxide	KCNA1 KCNA2 KCNA3 KCNA4 PRKCE	2.19e-04	227	55	5	CID000003019
Drug	naphthalene	SOX10 KCNA2 ALOX12 ALOX15	2.24e-04	123	55	4	CID000000931
Drug	1-methyladenine	CASR ALOX12 ALOX15	2.41e-04	50	55	3	CID000078821
Drug	EP 10045	ALOX12 ALOX15	2.55e-04	10	55	2	CID000127575
Drug	9-HPODE	ALOX12 ALOX15	2.55e-04	10	55	2	CID000001928
Drug	1,4-pentadiene	ALOX12 ALOX15	2.55e-04	10	55	2	CID000011587
Drug	eicosatetraynoic acid	KCNA4 ALOX12 ALOX15	2.56e-04	51	55	3	CID000135235
Drug	tetraethylammonium	KCNA1 KCNA2 KCNA3 KCNA4 PRKCE	2.62e-04	236	55	5	CID000005413
Drug	E 4031	KCNA1 KCNA2 KCNA3	3.03e-04	54	55	3	CID000003184
Drug	LTE5	ALOX12 ALOX15	3.11e-04	11	55	2	CID006439533
Drug	phorbolol myristate acetate	CASR PLCD1	3.11e-04	11	55	2	ctd:C016658
Drug	acetone phenylhydrazone	ALOX12 ALOX15	3.11e-04	11	55	2	CID000066026
Drug	Ity A	ALOX12 ALOX15	3.11e-04	11	55	2	CID000188274
Drug	BW A137C	ALOX12 ALOX15	3.11e-04	11	55	2	CID000129265
Disease	alopecia areata (is_marker_for)	KDM5A HDAC2	1.47e-04	10	54	2	DOID:986 (is_marker_for)
Disease	epilepsy (implicated_via_orthology)	KCNA1 KCNA2 KCNA3 KCNA4	2.29e-04	163	54	4	DOID:1826 (implicated_via_orthology)
Disease	Nonorganic psychosis	LMOD2 HDAC2 PCNT	2.79e-04	69	54	3	C0349204
Disease	Moyamoya Disease	BRCC3 PCNT	4.39e-04	17	54	2	C0026654
Disease	Psychotic Disorders	LMOD2 HDAC2 PCNT	8.51e-04	101	54	3	C0033975
Disease	Schizophrenia	MYT1L SOX10 PPP1R1B LMOD2 ALOX12 HDAC2 PCNT	1.09e-03	883	54	7	C0036341
Disease	Intellectual Disability	MYT1L SOX9 KCNA2 KDM5A MED13	1.34e-03	447	54	5	C3714756
Disease	asthma, Eczema, allergic rhinitis	TCHH CD247 ALOX15	1.43e-03	121	54	3	EFO_0005854, HP_0000964, MONDO_0004979
Disease	response to allopurinol, uric acid measurement	ANO2 KCNA1	1.57e-03	32	54	2	EFO_0004761, EFO_0006337
Disease	panic disorder	ANO2 KCNA3	1.67e-03	33	54	2	EFO_0004262
Disease	platelet crit	KCNA4 RBM27 SVIL KIF16B PRKCE ZNF318 LMOD2	1.68e-03	952	54	7	EFO_0007985
Disease	sphingomyelin measurement	TBKBP1 KIF16B CASR ALOX15	1.68e-03	278	54	4	EFO_0010118
Disease	chronic rhinosinusitis	SPEF2 ALOX15	1.78e-03	34	54	2	EFO_1000024

Protein segments in the cluster

Peptide	Gene	Start	Entry
EDKDEREAPPREGNL	ERBIN	466	Q96RT1
DDLFREADIEPNGKV	CALML4	166	Q96GE6
ERDKRPEGYNLKEED	PPP2R2A	126	P63151
QDGDLSPEEKIFLRE	APOL6	31	Q9BWW8
IPRTEDKEFDDLEER	ARHGEF37	261	A1IGU5
PGIEKFREEAEERDI	CASR	221	P41180
EEEAERDRLNIKSPF	GYS2	671	P54840
REPEQLGEDVERRIF	FAM186B	546	Q8IYM0
GPLDALEEERKEQRE	ANO2	146	Q9NQ90
LEEKQRAFEILDRGP	KIF16B	921	Q96L93
EDFRQLPEEDLREAP	RBM12B	841	Q8IXT5
EVFQEPAEEERDGRK	RBM27	101	Q9P2N5
FNEEFDLKDRDIGRP	ANKRD13A	336	Q8IZ07
FREDEGYIKEEERPL	KCNA2	126	P16389
LEEESLVGREPEERK	LAD1	156	O00515
EEEEEEREFRKQFPL	MDN1	3566	Q9NU22
REDEGFIKEEERPLP	KCNA1	131	Q09470
GEAPKDNEERVFRER	PRKCE	136	Q02156
KELERELEDIEPDRN	LMOD2	31	Q6P5Q4
EIDEDAFRKLPQLRE	EPYC	181	Q99645
GFPEEEDNGELRERL	PDZD7	681	Q9H5P4
EDFRGRRQEAPKVEE	CUEDC1	366	Q9NWM3
EQGLGKREEDEPEER	HNRNPUL2	146	Q1KMD3
KFREDEGFLREEERP	KCNA3	196	P22001
PVDERFLEDKRVDFE	ALOX15	161	P16050
ELQLRPARGEEEEFD	ALOX12	36	P18054
EKGRKDHVDELEPER	PCNT	571	O95613
DGRRKILPEEEEYAL	KDM5A	426	P29375
TEGLEKFARDVPEDR	PLCD1	81	P51178
PKREEEEDFIRAAFG	EXOC4	666	Q96A65
DLDKEDGRPLELRDL	CSF1R	741	P07333
GKDRELGPEELDELQ	CABP4	121	P57796
DFEEFVELIGPKLRE	CABP4	186	P57796
EEYDVLDKRRGRDPE	CD247	81	P20963
FEERLEDQERLKPEG	CRACD	426	Q6ZU35
DEDGEDPDKRISIRA	HDAC2	396	Q92769
DLSEFRKLPREEEEE	PPM1F	91	P49593
EFPEPEENAAREERK	SPEF2	1681	Q9C093
FDRREKESELGDRPL	SMCHD1	31	A6NHR9
SDDGELKIDEFPIRR	PHF2	681	O75151
LRDRLPFEEKVEVEN	SVIL	1031	O95425
QEERETRLFPAVDDK	WDR19	461	Q8NEZ3
LNESEKRPFVEEAER	SOX9	146	P48436
VEGDEEFLFPDKKDR	MED13	701	Q9UHV7
EGQKEEERYERIEIP	BRCC3	201	P46736
DEDEKRPFVEEAKRL	SOX15	91	O60248
NESDKRPFIEEAERL	SOX10	146	P56693
KRPRQEELEDFDKDG	SMC6	16	Q96SB8
LEDLERELDEPGKQV	ZSCAN16	116	Q9H4T2
DELGELRELGYPREE	PPP1R1B	106	Q9UD71
GIRLRFEKQPSEEDE	TBKBP1	511	A7MCY6
REQRFLPEEEEKEQR	TCHH	806	Q07283
DRKFREEEQLLQEGE	TCHH	1666	Q07283
LKAGDEIDEPSERER	ZNF512	226	Q96ME7
QEKRRRSFPDIEDEE	ZNF318	521	Q5VUA4
LLKFREDEGFVREEE	KCNA4	266	P22459
VREEEDRALPENEFK	KCNA4	276	P22459
PEDLDPFQEALEERR	MYT1L	841	Q9UL68