Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionproteoglycan binding

SLIT2 THBS1 SLIT1 COMP

2.19e-0751214GO:0043394
GeneOntologyMolecularFunctioncalcium ion binding

LRP2 SLIT2 LRP1B NID2 THBS1 SCUBE1 SLIT1 COMP

4.98e-07749218GO:0005509
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

SLIT2 SLIT1 COMP

3.60e-0629213GO:0043395
GeneOntologyMolecularFunctionextracellular matrix structural constituent

SLIT2 NID2 THBS1 COMP

4.02e-05188214GO:0005201
GeneOntologyMolecularFunctionheparin binding

SLIT2 THBS1 SLIT1 COMP

4.36e-05192214GO:0008201
GeneOntologyMolecularFunctionRoundabout binding

SLIT2 SLIT1

6.91e-0512212GO:0048495
GeneOntologyMolecularFunctioncollagen binding

NID2 THBS1 COMP

8.11e-0581213GO:0005518
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP2 LRP1B

1.25e-0416212GO:0005041
GeneOntologyMolecularFunctionglycosaminoglycan binding

SLIT2 THBS1 SLIT1 COMP

1.59e-04268214GO:0005539
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP2 LRP1B

2.19e-0421212GO:0030228
GeneOntologyMolecularFunctionsulfur compound binding

SLIT2 THBS1 SLIT1 COMP

3.24e-04323214GO:1901681
GeneOntologyMolecularFunctionlaminin binding

SLIT2 THBS1

5.79e-0434212GO:0043236
GeneOntologyMolecularFunctionfibronectin binding

THBS1 COMP

7.24e-0438212GO:0001968
GeneOntologyMolecularFunctionDNA secondary structure binding

FANCM LIN54

8.43e-0441212GO:0000217
GeneOntologyMolecularFunctionextracellular matrix binding

SLIT2 THBS1

2.65e-0373212GO:0050840
GeneOntologyMolecularFunctionlipid binding

C3 THBS1 MCOLN3 SNX5 COMP

3.08e-03988215GO:0008289
GeneOntologyMolecularFunctioncargo receptor activity

LRP2 LRP1B

3.57e-0385212GO:0038024
GeneOntologyBiologicalProcesschemorepulsion involved in embryonic olfactory bulb interneuron precursor migration

SLIT2 SLIT1

2.96e-063212GO:0021834
GeneOntologyBiologicalProcessdorsal/ventral axon guidance

SLIT2 SLIT1

5.92e-064212GO:0033563
GeneOntologyBiologicalProcessnegative regulation of axon extension

TTC3 SLIT2 SLIT1

7.50e-0638213GO:0030517
GeneOntologyBiologicalProcessembryonic olfactory bulb interneuron precursor migration

SLIT2 SLIT1

9.85e-065212GO:0021831
GeneOntologyBiologicalProcessdevelopmental growth

TTC3 SLIT2 C3 THBS1 EIF2AK4 SLIT1 COMP

2.16e-05911217GO:0048589
GeneOntologyBiologicalProcessnegative regulation of chemotaxis

SLIT2 THBS1 SLIT1

2.18e-0554213GO:0050922
GeneOntologyBiologicalProcessnegative regulation of axonogenesis

TTC3 SLIT2 SLIT1

3.31e-0562213GO:0050771
GeneOntologyBiologicalProcesstangential migration from the subventricular zone to the olfactory bulb

SLIT2 SLIT1

4.42e-0510212GO:0022028
GeneOntologyBiologicalProcessneuron projection extension

TTC3 SLIT2 EIF2AK4 SLIT1

5.16e-05207214GO:1990138
GeneOntologyBiologicalProcessolfactory bulb interneuron development

SLIT2 SLIT1

5.40e-0511212GO:0021891
GeneOntologyBiologicalProcesssubstrate-independent telencephalic tangential migration

SLIT2 SLIT1

7.65e-0513212GO:0021826
GeneOntologyBiologicalProcesssubstrate-independent telencephalic tangential interneuron migration

SLIT2 SLIT1

7.65e-0513212GO:0021843
GeneOntologyBiologicalProcessgrowth

TTC3 SLIT2 C3 THBS1 EIF2AK4 SLIT1 COMP

1.50e-041235217GO:0040007
GeneOntologyBiologicalProcessregulation of axon extension

TTC3 SLIT2 SLIT1

1.55e-04104213GO:0030516
GeneOntologyBiologicalProcessdevelopmental growth involved in morphogenesis

TTC3 SLIT2 EIF2AK4 SLIT1

2.13e-04299214GO:0060560
GeneOntologyBiologicalProcessdevelopmental cell growth

TTC3 SLIT2 EIF2AK4 SLIT1

2.19e-04301214GO:0048588
GeneOntologyBiologicalProcessaxon extension involved in axon guidance

SLIT2 SLIT1

2.25e-0422212GO:0048846
GeneOntologyBiologicalProcessneuron projection extension involved in neuron projection guidance

SLIT2 SLIT1

2.25e-0422212GO:1902284
GeneOntologyBiologicalProcessregulation of extent of cell growth

TTC3 SLIT2 SLIT1

2.48e-04122213GO:0061387
GeneOntologyBiologicalProcessretinal ganglion cell axon guidance

SLIT2 SLIT1

2.69e-0424212GO:0031290
GeneOntologyBiologicalProcessnegative regulation of developmental growth

TTC3 SLIT2 SLIT1

2.73e-04126213GO:0048640
GeneOntologyBiologicalProcessolfactory bulb interneuron differentiation

SLIT2 SLIT1

3.16e-0426212GO:0021889
GeneOntologyBiologicalProcessaxon extension

TTC3 SLIT2 SLIT1

3.35e-04135213GO:0048675
GeneOntologyBiologicalProcesscirculatory system development

LRP2 SLIT2 C3 THBS1 SCUBE1 CEP290 COMP

3.91e-041442217GO:0072359
GeneOntologyBiologicalProcessgrowth plate cartilage development

THBS1 COMP

3.94e-0429212GO:0003417
GeneOntologyBiologicalProcessneuron development

TTC3 LRP2 SLIT2 C3 EIF2AK4 SLIT1 CEP290

4.27e-041463217GO:0048666
GeneOntologyBiologicalProcessresponse to unfolded protein

THBS1 EIF2AK4 COMP

4.38e-04148213GO:0006986
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

LRP2 SLIT2 THBS1

4.55e-04150213GO:0090288
GeneOntologyBiologicalProcesskidney development

LRP2 SLIT2 CEP290 PLCE1

4.89e-04372214GO:0001822
GeneOntologyBiologicalProcessrenal system development

LRP2 SLIT2 CEP290 PLCE1

5.62e-04386214GO:0072001
GeneOntologyBiologicalProcessmotor neuron axon guidance

SLIT2 SLIT1

5.76e-0435212GO:0008045
GeneOntologyBiologicalProcessresponse to topologically incorrect protein

THBS1 EIF2AK4 COMP

6.12e-04166213GO:0035966
GeneOntologyBiologicalProcessnegative regulation of neuron projection development

TTC3 SLIT2 SLIT1

6.45e-04169213GO:0010977
GeneOntologyBiologicalProcessnegative regulation of neurogenesis

TTC3 SLIT2 SLIT1

6.90e-04173213GO:0050768
GeneOntologyBiologicalProcesstube morphogenesis

LRP2 SLIT2 C3 THBS1 CEP290 COMP

6.94e-041125216GO:0035239
GeneOntologyBiologicalProcessendochondral bone growth

THBS1 COMP

7.15e-0439212GO:0003416
GeneOntologyBiologicalProcessamyloid-beta clearance

LRP2 C3

7.52e-0440212GO:0097242
GeneOntologyBiologicalProcessregulation of developmental growth

TTC3 SLIT2 C3 SLIT1

7.77e-04421214GO:0048638
GeneOntologyBiologicalProcessnegative regulation of cell junction assembly

THBS1 SLIT1

7.90e-0441212GO:1901889
GeneOntologyBiologicalProcessheart development

LRP2 SLIT2 THBS1 SCUBE1 CEP290

8.19e-04757215GO:0007507
GeneOntologyBiologicalProcessnegative regulation of nervous system development

TTC3 SLIT2 SLIT1

8.25e-04184213GO:0051961
GeneOntologyBiologicalProcessregulation of axonogenesis

TTC3 SLIT2 SLIT1

9.33e-04192213GO:0050770
GeneOntologyBiologicalProcessbone growth

THBS1 COMP

9.52e-0445212GO:0098868
GeneOntologyBiologicalProcessregulation of lamellipodium assembly

SLIT2 PLCE1

9.52e-0445212GO:0010591
GeneOntologyBiologicalProcesscartilage development involved in endochondral bone morphogenesis

THBS1 COMP

1.04e-0347212GO:0060351
GeneOntologyBiologicalProcessneuron projection morphogenesis

TTC3 LRP2 SLIT2 EIF2AK4 SLIT1

1.06e-03802215GO:0048812
GeneOntologyBiologicalProcessapoptotic cell clearance

C3 THBS1

1.08e-0348212GO:0043277
GeneOntologyBiologicalProcessblood vessel morphogenesis

LRP2 SLIT2 C3 THBS1 COMP

1.15e-03817215GO:0048514
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

TTC3 LRP2 SLIT2 EIF2AK4 SLIT1

1.17e-03819215GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

TTC3 LRP2 SLIT2 EIF2AK4 SLIT1

1.21e-03826215GO:0048858
GeneOntologyBiologicalProcessendocytosis

LRP2 LRP1B C3 THBS1 SNX5

1.22e-03827215GO:0006897
GeneOntologyBiologicalProcessnegative chemotaxis

SLIT2 SLIT1

1.22e-0351212GO:0050919
GeneOntologyBiologicalProcessnegative regulation of cell growth

TTC3 SLIT2 SLIT1

1.24e-03212213GO:0030308
GeneOntologyBiologicalProcessanimal organ morphogenesis

LRP2 SLIT2 THBS1 SLIT1 CEP290 COMP

1.30e-031269216GO:0009887
GeneOntologyBiologicalProcessolfactory bulb development

SLIT2 SLIT1

1.32e-0353212GO:0021772
GeneOntologyBiologicalProcessvascular associated smooth muscle cell differentiation

C3 COMP

1.42e-0355212GO:0035886
GeneOntologyBiologicalProcessolfactory lobe development

SLIT2 SLIT1

1.47e-0356212GO:0021988
GeneOntologyBiologicalProcessregulation of cell size

TTC3 SLIT2 SLIT1

1.47e-03225213GO:0008361
GeneOntologyBiologicalProcessregulation of lamellipodium organization

SLIT2 PLCE1

1.52e-0357212GO:1902743
GeneOntologyBiologicalProcessnegative regulation of cell projection organization

TTC3 SLIT2 SLIT1

1.63e-03233213GO:0031345
GeneOntologyBiologicalProcessregulation of neurogenesis

TTC3 LRP2 SLIT2 SLIT1

1.64e-03515214GO:0050767
GeneOntologyBiologicalProcesschemotaxis

LRP2 SLIT2 THBS1 SLIT1

1.66e-03517214GO:0006935
GeneOntologyBiologicalProcesstaxis

LRP2 SLIT2 THBS1 SLIT1

1.69e-03519214GO:0042330
GeneOntologyBiologicalProcessregulation of chemotaxis

SLIT2 THBS1 SLIT1

1.81e-03242213GO:0050920
GeneOntologyBiologicalProcessneutral lipid biosynthetic process

C3 PLCE1

1.86e-0363212GO:0046460
GeneOntologyBiologicalProcessacylglycerol biosynthetic process

C3 PLCE1

1.86e-0363212GO:0046463
GeneOntologyBiologicalProcessregulation of granulocyte chemotaxis

SLIT2 THBS1

1.98e-0365212GO:0071622
GeneOntologyBiologicalProcessblood vessel development

LRP2 SLIT2 C3 THBS1 COMP

2.04e-03929215GO:0001568
GeneOntologyBiologicalProcesstube development

LRP2 SLIT2 C3 THBS1 CEP290 COMP

2.18e-031402216GO:0035295
GeneOntologyBiologicalProcessphagocytosis, engulfment

C3 THBS1

2.22e-0369212GO:0006911
GeneOntologyBiologicalProcessblood coagulation

THBS1 SCUBE1 COMP

2.23e-03260213GO:0007596
GeneOntologyBiologicalProcessnegative regulation of hemostasis

THBS1 COMP

2.29e-0370212GO:1900047
GeneOntologyBiologicalProcessaxonogenesis

TTC3 LRP2 SLIT2 SLIT1

2.32e-03566214GO:0007409
GeneOntologyBiologicalProcesscoagulation

THBS1 SCUBE1 COMP

2.38e-03266213GO:0050817
GeneOntologyBiologicalProcesstelencephalon cell migration

SLIT2 SLIT1

2.42e-0372212GO:0022029
GeneOntologyBiologicalProcesshemostasis

THBS1 SCUBE1 COMP

2.43e-03268213GO:0007599
GeneOntologyBiologicalProcessvasculature development

LRP2 SLIT2 C3 THBS1 COMP

2.46e-03969215GO:0001944
GeneOntologyBiologicalProcessforebrain cell migration

SLIT2 SLIT1

2.62e-0375212GO:0021885
GeneOntologyBiologicalProcessepithelium development

LRP2 SLIT2 C3 MCOLN3 SCUBE1 CEP290

2.76e-031469216GO:0060429
GeneOntologyBiologicalProcessplasma membrane invagination

C3 THBS1

2.83e-0378212GO:0099024
GeneOntologyBiologicalProcessnegative regulation of growth

TTC3 SLIT2 SLIT1

2.83e-03283213GO:0045926
GeneOntologyBiologicalProcessaxon guidance

LRP2 SLIT2 SLIT1

2.89e-03285213GO:0007411
GeneOntologyCellularComponentcell surface

LRP2 SLIT2 NID2 C3 THBS1 SCUBE1

6.05e-041111216GO:0009986
GeneOntologyCellularComponentcollagen-containing extracellular matrix

SLIT2 NID2 THBS1 COMP

1.73e-03530214GO:0062023
GeneOntologyCellularComponentextracellular matrix

SLIT2 NID2 THBS1 COMP

3.76e-03656214GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

SLIT2 NID2 THBS1 COMP

3.80e-03658214GO:0030312
GeneOntologyCellularComponentsecretory granule lumen

C3 THBS1 CEP290

4.02e-03325213GO:0034774
GeneOntologyCellularComponentcytoplasmic vesicle lumen

C3 THBS1 CEP290

4.20e-03330213GO:0060205
GeneOntologyCellularComponentvesicle lumen

C3 THBS1 CEP290

4.27e-03332213GO:0031983
DomainEGF_CA

LRP2 SLIT2 LRP1B NID2 THBS1 SCUBE1 SLIT1 COMP

4.98e-13122218SM00179
DomainEGF-like_Ca-bd_dom

LRP2 SLIT2 LRP1B NID2 THBS1 SCUBE1 SLIT1 COMP

5.69e-13124218IPR001881
DomainEGF_Ca-bd_CS

LRP2 SLIT2 LRP1B NID2 SCUBE1 SLIT1 COMP

8.96e-1297217IPR018097
DomainEGF_CA

LRP2 SLIT2 LRP1B NID2 SCUBE1 SLIT1 COMP

1.04e-1199217PS01187
DomainEGF_3

LRP2 SLIT2 LRP1B NID2 THBS1 SCUBE1 SLIT1 COMP

9.85e-11235218PS50026
DomainEGF

LRP2 SLIT2 LRP1B NID2 THBS1 SCUBE1 SLIT1 COMP

9.85e-11235218SM00181
DomainEGF-like_dom

LRP2 SLIT2 LRP1B NID2 THBS1 SCUBE1 SLIT1 COMP

1.56e-10249218IPR000742
DomainEGF-like_CS

LRP2 SLIT2 LRP1B NID2 THBS1 SCUBE1 SLIT1 COMP

2.27e-10261218IPR013032
DomainEGF_2

LRP2 SLIT2 LRP1B NID2 THBS1 SCUBE1 SLIT1 COMP

2.56e-10265218PS01186
DomainEGF_CA

LRP2 LRP1B NID2 THBS1 SCUBE1 COMP

4.10e-1086216PF07645
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP2 SLIT2 LRP1B NID2 SCUBE1 SLIT1

1.47e-09106216IPR000152
DomainEGF_1

LRP2 SLIT2 LRP1B THBS1 SCUBE1 SLIT1 COMP

8.05e-09255217PS00022
DomainGrowth_fac_rcpt_

LRP2 LRP1B NID2 SCUBE1 SLIT1 COMP

1.51e-08156216IPR009030
DomaincEGF

LRP2 LRP1B NID2 SCUBE1

1.74e-0826214IPR026823
DomaincEGF

LRP2 LRP1B NID2 SCUBE1

1.74e-0826214PF12662
DomainASX_HYDROXYL

LRP2 SLIT2 LRP1B NID2 SCUBE1

7.56e-08100215PS00010
DomainEGF

LRP2 SLIT2 LRP1B NID2 SLIT1

2.41e-07126215PF00008
DomainLdl_recept_b

LRP2 LRP1B NID2

4.42e-0714213PF00058
DomainLDLRB

LRP2 LRP1B NID2

4.42e-0714213PS51120
DomainLY

LRP2 LRP1B NID2

5.53e-0715213SM00135
DomainLDLR_classB_rpt

LRP2 LRP1B NID2

5.53e-0715213IPR000033
Domain-

SLIT2 THBS1 SLIT1 COMP

3.52e-06952142.60.120.200
Domain-

LRP2 LRP1B NID2

1.09e-05392132.120.10.30
DomainTSP3

THBS1 COMP

1.20e-055212PS51234
DomainTSP_CTER

THBS1 COMP

1.20e-055212PS51236
Domain-

THBS1 COMP

1.20e-0552124.10.1080.10
DomainThrombospondin_C

THBS1 COMP

1.20e-055212IPR008859
DomainTSP_C

THBS1 COMP

1.20e-055212PF05735
DomainThrombospondin_3_rpt

THBS1 COMP

1.20e-055212IPR017897
DomainTSP_3

THBS1 COMP

1.20e-055212PF02412
DomainThrombospondin_3-like_rpt

THBS1 COMP

1.20e-055212IPR003367
DomainTSP_type-3_rpt

THBS1 COMP

1.20e-055212IPR028974
Domain6-blade_b-propeller_TolB-like

LRP2 LRP1B NID2

1.80e-0546213IPR011042
DomainLaminin_G

SLIT2 THBS1 SLIT1

3.63e-0558213IPR001791
DomainFol_N

SLIT2 SLIT1

6.58e-0511212IPR003645
DomainFOLN

SLIT2 SLIT1

6.58e-0511212SM00274
DomainEGF_3

NID2 SCUBE1

7.89e-0512212PF12947
DomainEGF_dom

NID2 SCUBE1

7.89e-0512212IPR024731
DomainConA-like_dom

SLIT2 THBS1 SLIT1 COMP

9.41e-05219214IPR013320
DomainCTCK_1

SLIT2 SLIT1

1.82e-0418212PS01185
DomainCT

SLIT2 SLIT1

2.74e-0422212SM00041
DomainCys_knot_C

SLIT2 SLIT1

3.56e-0425212IPR006207
DomainCTCK_2

SLIT2 SLIT1

3.56e-0425212PS01225
DomainhEGF

SLIT2 SLIT1

4.47e-0428212PF12661
DomainLRRCT

SLIT2 SLIT1

5.85e-0432212PF01463
DomainLAM_G_DOMAIN

SLIT2 SLIT1

8.26e-0438212PS50025
DomainLaminin_G_2

SLIT2 SLIT1

9.15e-0440212PF02210
DomainLDLR_class-A_CS

LRP2 LRP1B

9.15e-0440212IPR023415
DomainLamG

SLIT2 SLIT1

1.11e-0344212SM00282
DomainLdl_recept_a

LRP2 LRP1B

1.16e-0345212PF00057
Domain-

LRP2 LRP1B

1.21e-03462124.10.400.10
DomainLDLRA_1

LRP2 LRP1B

1.32e-0348212PS01209
DomainLDrepeatLR_classA_rpt

LRP2 LRP1B

1.37e-0349212IPR002172
DomainLDLa

LRP2 LRP1B

1.37e-0349212SM00192
DomainLDLRA_2

LRP2 LRP1B

1.37e-0349212PS50068
DomainLRRNT

SLIT2 SLIT1

1.60e-0353212PF01462
DomainEGF_extracell

LRP2 LRP1B

2.05e-0360212IPR013111
DomainEGF_2

LRP2 LRP1B

2.05e-0360212PF07974
DomainCys-rich_flank_reg_C

SLIT2 SLIT1

4.54e-0390212IPR000483
DomainLRRCT

SLIT2 SLIT1

4.54e-0390212SM00082
DomainLRRNT

SLIT2 SLIT1

5.36e-0398212IPR000372
DomainLRRNT

SLIT2 SLIT1

5.36e-0398212SM00013
PathwayREACTOME_REGULATION_OF_COMMISSURAL_AXON_PATHFINDING_BY_SLIT_AND_ROBO

SLIT2 SLIT1

7.70e-0510192M27348
PathwayWP_COMPLEMENT_SYSTEM

LRP2 C3 THBS1

2.74e-0496193M39581
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

NID2 THBS1 SCUBE1 COMP

3.42e-04258194MM14572
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

NID2 THBS1 SCUBE1 COMP

6.05e-04300194M610
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

SLIT2 NID2 C3 THBS1 COMP

3.28e-0724821524006456
Pubmed

Serum COMP-C3b complexes in rheumatic diseases and relation to anti-TNF-α treatment.

C3 COMP

3.47e-07221222264230
Pubmed

Permissive corridor and diffusible gradients direct medial ganglionic eminence cell migration to the neocortex.

SLIT2 SLIT1

3.47e-07221212515855
Pubmed

Cartilage oligomeric matrix protein-induced complement activation in systemic sclerosis.

C3 COMP

3.47e-07221224330664
Pubmed

Steerable-filter based quantification of axonal populations at the developing optic chiasm reveal significant defects in Slit2(-/-) as well as Slit1(-/-)Slit2(-/-) embryos.

SLIT2 SLIT1

3.47e-07221223320558
Pubmed

Slit1 and slit2 proteins control the development of the lateral olfactory tract.

SLIT2 SLIT1

3.47e-07221212097499
Pubmed

Slit proteins: molecular guidance cues for cells ranging from neurons to leukocytes.

SLIT2 SLIT1

3.47e-07221212200164
Pubmed

Intermolecular interactions of thrombospondins drive their accumulation in extracellular matrix.

THBS1 COMP

3.47e-07221225995382
Pubmed

COMP-C3b complexes in rheumatoid arthritis with severe extraarticular manifestations.

C3 COMP

3.47e-07221224187101
Pubmed

Directional guidance of neuronal migration in the olfactory system by the protein Slit.

SLIT2 SLIT1

3.47e-07221210432110
Pubmed

Genetic link between renal birth defects and congenital heart disease.

LRP2 SLIT2 CEP290

6.15e-072821327002738
Pubmed

Slit-mediated repulsion is a key regulator of motor axon pathfinding in the hindbrain.

SLIT2 SLIT1

1.04e-06321216162649
Pubmed

Extracellular matrix retention of thrombospondin 1 is controlled by its conserved C-terminal region.

THBS1 COMP

1.04e-06321218285447
Pubmed

Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system.

SLIT2 SLIT1

1.04e-0632129813312
Pubmed

A molecular mechanism for the heparan sulfate dependence of slit-robo signaling.

SLIT2 SLIT1

1.04e-06321217062560
Pubmed

Conserved modularity and potential for alternate splicing in mouse and human Slit genes.

SLIT2 SLIT1

1.04e-06321212141424
Pubmed

New neurons follow the flow of cerebrospinal fluid in the adult brain.

SLIT2 SLIT1

1.04e-06321216410488
Pubmed

Mammalian homologues of the Drosophila slit protein are ligands of the heparan sulfate proteoglycan glypican-1 in brain.

SLIT2 SLIT1

1.04e-06321210364234
Pubmed

Intraislet SLIT-ROBO signaling is required for beta-cell survival and potentiates insulin secretion.

SLIT2 SLIT1

1.04e-06321224065825
Pubmed

Axonal growth regulation of fetal and embryonic stem cell-derived dopaminergic neurons by Netrin-1 and Slits.

SLIT2 SLIT1

1.04e-06321216840550
Pubmed

ADAMTS-7 inhibits re-endothelialization of injured arteries and promotes vascular remodeling through cleavage of thrombospondin-1.

THBS1 COMP

1.04e-06321225712208
Pubmed

Thrombospondin-1, -2 and -5 have differential effects on vascular smooth muscle cell physiology.

THBS1 COMP

1.04e-06321226168731
Pubmed

Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.

LRP2 THBS1

2.08e-0642127775583
Pubmed

The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis and axon guidance.

SLIT2 SLIT1

2.08e-06421210433822
Pubmed

Multiple roles for slits in the control of cell migration in the rostral migratory stream.

SLIT2 SLIT1

2.08e-06421214960623
Pubmed

Contralateral migration of oculomotor neurons is regulated by Slit/Robo signaling.

SLIT2 SLIT1

2.08e-06421227770832
Pubmed

Slits contribute to the guidance of retinal ganglion cell axons in the mammalian optic tract.

SLIT2 SLIT1

2.08e-06421216828733
Pubmed

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.

THBS1 COMP

3.47e-06521230622267
Pubmed

Slit and robo: expression patterns in lung development.

SLIT2 SLIT1

3.47e-06521212609596
Pubmed

Extracellular Ig domains 1 and 2 of Robo are important for ligand (Slit) binding.

SLIT2 SLIT1

3.47e-06521215207848
Pubmed

Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen.

THBS1 COMP

3.47e-06521218467703
Pubmed

Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization.

SLIT2 SLIT1

3.47e-06521225894826
Pubmed

Expression patterns of Slit and Robo family members in adult mouse spinal cord and peripheral nervous system.

SLIT2 SLIT1

3.47e-06521228234971
Pubmed

On the topographic targeting of basal vomeronasal axons through Slit-mediated chemorepulsion.

SLIT2 SLIT1

3.47e-06521212954717
Pubmed

Slit1 is specifically expressed in the primary and secondary enamel knots during molar tooth cusp formation.

SLIT2 SLIT1

3.47e-06521211520671
Pubmed

Emergent growth cone responses to combinations of Slit1 and Netrin 1 in thalamocortical axon topography.

SLIT2 SLIT1

3.47e-06521222000108
Pubmed

Slit proteins regulate distinct aspects of retinal ganglion cell axon guidance within dorsal and ventral retina.

SLIT2 SLIT1

3.47e-06521216885222
Pubmed

Midbrain dopaminergic axons are guided longitudinally through the diencephalon by Slit/Robo signals.

SLIT2 SLIT1

3.47e-06521221118670
Pubmed

Slit proteins are not dominant chemorepellents for olfactory tract and spinal motor axons.

SLIT2 SLIT1

3.47e-06521211748139
Pubmed

Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system.

SLIT2 SLIT1

5.20e-06621211804570
Pubmed

SLITs suppress tumor growth in vivo by silencing Sdf1/Cxcr4 within breast epithelium.

SLIT2 SLIT1

5.20e-06621218829537
Pubmed

Slit antagonizes netrin-1 attractive effects during the migration of inferior olivary neurons.

SLIT2 SLIT1

5.20e-06621212051827
Pubmed

The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons.

SLIT2 SLIT1

5.20e-06621218054781
Pubmed

Slit2 is a repellent for retinal ganglion cell axons.

SLIT2 SLIT1

5.20e-06621210864954
Pubmed

Robo1 and robo2 control the development of the lateral olfactory tract.

SLIT2 SLIT1

5.20e-06621217360927
Pubmed

Slit2 and netrin 1 act synergistically as adhesive cues to generate tubular bi-layers during ductal morphogenesis.

SLIT2 SLIT1

5.20e-06621216439476
Pubmed

Pioneer longitudinal axons navigate using floor plate and Slit/Robo signals.

SLIT2 SLIT1

5.20e-06621218842816
Pubmed

Robo2 Receptor Gates the Anatomical Divergence of Neurons Derived From a Common Precursor Origin.

SLIT2 SLIT1

5.20e-06621234249921
Pubmed

Autocrine/juxtaparacrine regulation of axon fasciculation by Slit-Robo signaling.

SLIT2 SLIT1

5.20e-06621222306607
Pubmed

Slit/Robo-mediated chemorepulsion of vagal sensory axons in the fetal gut.

SLIT2 SLIT1

5.20e-06621223161783
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TTC3 LRP2 LRP1B THBS1 CEP290 MORC3 SNX5

6.82e-06128521735914814
Pubmed

Islet architecture: A comparative study.

SLIT2 SLIT1

7.28e-06721220606719
Pubmed

VEGF-A and neuropilin 1 (NRP1) shape axon projections in the developing CNS via dual roles in neurons and blood vessels.

SLIT2 SLIT1

7.28e-06721228676569
Pubmed

Slit-Robo signals regulate pioneer axon pathfinding of the tract of the postoptic commissure in the mammalian forebrain.

SLIT2 SLIT1

7.28e-06721221688288
Pubmed

Slit molecules prevent entrance of trunk neural crest cells in developing gut.

SLIT2 SLIT1

7.28e-06721225490618
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

SLIT2 C3 THBS1 SCUBE1 SLIT1

7.90e-0647521531040226
Pubmed

Slit/Robo signaling mediates spatial positioning of spiral ganglion neurons during development of cochlear innervation.

SLIT2 SLIT1

9.70e-06821223884932
Pubmed

Robos and slits control the pathfinding and targeting of mouse olfactory sensory axons.

SLIT2 SLIT1

9.70e-06821218417704
Pubmed

Dual branch-promoting and branch-repelling actions of Slit/Robo signaling on peripheral and central branches of developing sensory axons.

SLIT2 SLIT1

9.70e-06821217581972
Pubmed

Conserved roles for Slit and Robo proteins in midline commissural axon guidance.

SLIT2 SLIT1

9.70e-06821215091338
Pubmed

Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.

THBS1 COMP

9.70e-06821224460873
Pubmed

Multiple Slits regulate the development of midline glial populations and the corpus callosum.

SLIT2 SLIT1

9.70e-06821222349628
Pubmed

Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation.

SLIT2 COMP

9.70e-06821216774856
Pubmed

Slit and robo expression in the developing mouse lung.

SLIT2 SLIT1

9.70e-06821215162513
Pubmed

Motor axons are guided to exit points in the spinal cord by Slit and Netrin signals.

SLIT2 SLIT1

9.70e-06821228986144
Pubmed

PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments.

SLIT2 SLIT1

9.70e-06821225485759
Pubmed

Robo1 and Robo2 cooperate to control the guidance of major axonal tracts in the mammalian forebrain.

SLIT2 SLIT1

9.70e-06821217392456
Pubmed

Slit2 and Robo3 modulate the migration of GnRH-secreting neurons.

SLIT2 SLIT1

9.70e-06821222912413
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

TTC3 LRP2 THBS1

1.06e-057121333541421
Pubmed

LDL receptor-related protein as a component of the midkine receptor.

LRP2 NID2

1.25e-05921210772929
Pubmed

Retinal ganglion cell axon guidance in the mouse optic chiasm: expression and function of robos and slits.

SLIT2 SLIT1

1.25e-05921210864955
Pubmed

Pioneer midbrain longitudinal axons navigate using a balance of Netrin attraction and Slit repulsion.

SLIT2 SLIT1

1.25e-05921225056828
Pubmed

Cooperative slit and netrin signaling in contralateralization of the mouse trigeminothalamic pathway.

SLIT2 SLIT1

1.25e-05921222806432
Pubmed

Collaborative and specialized functions of Robo1 and Robo2 in spinal commissural axon guidance.

SLIT2 SLIT1

1.25e-05921220631173
Pubmed

Heparan sulfate sugar modifications mediate the functions of slits and other factors needed for mouse forebrain commissure development.

SLIT2 SLIT1

1.56e-051021221307234
Pubmed

Slit/Robo signals prevent spinal motor neuron emigration by organizing the spinal cord basement membrane.

SLIT2 SLIT1

1.56e-051021231356769
Pubmed

Extracellular Fibrinogen-binding Protein (Efb) from Staphylococcus aureus Inhibits the Formation of Platelet-Leukocyte Complexes.

C3 THBS1

1.56e-051021226627825
Pubmed

Directional guidance of interneuron migration to the cerebral cortex relies on subcortical Slit1/2-independent repulsion and cortical attraction.

SLIT2 SLIT1

1.56e-051021212642493
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

NID2 C3 THBS1 LIN54 CEP290

1.81e-0556421521565611
Pubmed

Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain.

SLIT2 SLIT1

1.90e-051121211804571
Pubmed

Motor axon exit from the mammalian spinal cord is controlled by the homeodomain protein Nkx2.9 via Robo-Slit signaling.

SLIT2 SLIT1

1.90e-051121222399681
Pubmed

Knockdown of slit signaling during limb development leads to a reduction in humerus length.

SLIT2 SLIT1

1.90e-051121233347679
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP2 LRP1B

1.90e-051121224639464
Pubmed

Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons.

SLIT2 SLIT1

1.90e-051121226520399
Pubmed

Molecular mechanisms controlling midline crossing by precerebellar neurons.

SLIT2 SLIT1

1.90e-051121218562598
Pubmed

Slits and Robo-2 regulate the coalescence of subsets of olfactory sensory neuron axons within the ventral region of the olfactory bulb.

SLIT2 SLIT1

2.28e-051221222981605
Pubmed

Robo2 is required for Slit-mediated intraretinal axon guidance.

SLIT2 SLIT1

2.28e-051221219782674
Pubmed

Roundabout receptors are critical for foregut separation from the body wall.

SLIT2 SLIT1

2.28e-051221223328398
Pubmed

Sim1 and Sim2 are required for the correct targeting of mammillary body axons.

SLIT2 SLIT1

2.28e-051221216291793
Pubmed

Zinc-finger gene Fez in the olfactory sensory neurons regulates development of the olfactory bulb non-cell-autonomously.

SLIT2 SLIT1

2.28e-051221216540508
Pubmed

Dual role for LIM-homeodomain gene Lhx2 in the formation of the lateral olfactory tract.

SLIT2 SLIT1

2.28e-051221217329426
Pubmed

Patterning of the basal telencephalon and hypothalamus is essential for guidance of cortical projections.

SLIT2 SLIT1

2.28e-051221211830575
Pubmed

Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb.

SLIT2 SLIT1

2.28e-051221219906969
Pubmed

Role of neuropilin-2 in the ipsilateral growth of midbrain dopaminergic axons.

SLIT2 SLIT1

2.70e-051321223534961
Pubmed

Expression of Slit and Robo genes in the developing mouse heart.

SLIT2 SLIT1

2.70e-051321220941780
Pubmed

Developmental guidance of the retroflex tract at its bending point involves Robo1-Slit2-mediated floor plate repulsion.

SLIT2 SLIT1

2.70e-051321225366972
Pubmed

Tbx1 controls cardiac neural crest cell migration during arch artery development by regulating Gbx2 expression in the pharyngeal ectoderm.

SLIT2 SLIT1

2.70e-051321219700621
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

LRP2 SLIT2 CEP290

2.95e-0510021325807483
Pubmed

Proteomics characterization of extracellular space components in the human aorta.

NID2 THBS1 COMP

3.04e-0510121320551380
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

LRP2 LRP1B

3.15e-051421215082773
CytobandEnsembl 112 genes in cytogenetic band chr21q22

TTC3 URB1 MORC3

6.55e-04377213chr21q22
CytobandEnsembl 112 genes in cytogenetic band chr15q15

PPIP5K1 EIF2AK4

2.05e-03147212chr15q15
GeneFamilyLow density lipoprotein receptors

LRP2 LRP1B

2.14e-0513102634
CoexpressionNABA_ECM_GLYCOPROTEINS

SLIT2 NID2 THBS1 SLIT1 COMP

3.61e-07191215MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

SLIT2 NID2 THBS1 SLIT1 COMP

4.10e-07196215M3008
CoexpressionNABA_CORE_MATRISOME

SLIT2 NID2 THBS1 SLIT1 COMP

1.99e-06270215MM17057
CoexpressionNABA_CORE_MATRISOME

SLIT2 NID2 THBS1 SLIT1 COMP

2.17e-06275215M5884
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

SLIT2 NID2 THBS1 COMP

1.78e-05200214M5930
CoexpressionGSE23925_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN

PPIP5K1 MCOLN3 SNX5 COMP

1.78e-05200214M7878
CoexpressionNABA_MATRISOME

SLIT2 NID2 THBS1 SCUBE1 SLIT1 COMP

1.05e-041008216MM17056
CoexpressionNABA_MATRISOME

SLIT2 NID2 THBS1 SCUBE1 SLIT1 COMP

1.16e-041026216M5889
CoexpressionCHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP

C3 THBS1 EIF2AK4

1.20e-04121213M12828
CoexpressionBENPORATH_SUZ12_TARGETS

LRP2 SLIT2 NID2 MCOLN3 SLIT1 COMP

1.22e-041035216M9898
CoexpressionBENPORATH_PRC2_TARGETS

LRP2 SLIT2 MCOLN3 SLIT1 COMP

1.35e-04650215M8448
CoexpressionCHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP

C3 THBS1 EIF2AK4

1.55e-04132213MM465
CoexpressionHALLMARK_COAGULATION

C3 THBS1 COMP

1.77e-04138213M5946
CoexpressionSCHOEN_NFKB_SIGNALING

C3 THBS1

3.38e-0434212M1983
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

SLIT2 SCUBE1 SLIT1 COMP

3.67e-04438214M1954
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

SLIT2 SCUBE1 SLIT1 COMP

3.74e-04440214MM832
CoexpressionVECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP

SLIT2 NID2 THBS1

3.74e-04178213M17079
CoexpressionDELYS_THYROID_CANCER_UP

C3 THBS1 SLIT1 COMP

3.90e-04445214M3645
CoexpressionDESCARTES_FETAL_STOMACH_MESOTHELIAL_CELLS

LRP2 C3

4.00e-0437212M40310
CoexpressionNABA_MATRISOME_POORLY_METASTATIC_MELANOMA

NID2 THBS1

4.22e-0438212M47982
CoexpressionGSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDC_DN

C3 THBS1 MORC3

5.18e-04199213M4142
CoexpressionGSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_DC_DN

LRP2 SLIT2 PLCE1

5.18e-04199213M5151
CoexpressionGSE14308_INDUCED_VS_NATURAL_TREG_UP

ESCO2 PPIP5K1 C3

5.26e-04200213M3396
CoexpressionGSE11961_FOLLICULAR_BCELL_VS_GERMINAL_CENTER_BCELL_DAY7_DN

FANCM SLIT2 COMP

5.26e-04200213M9341
CoexpressionGSE23568_ID3_KO_VS_WT_CD8_TCELL_DN

FANCM EIF2AK4 SNX5

5.26e-04200213M8518
CoexpressionGSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_DN

TTC3 MCOLN3 SNX5

5.26e-04200213M4463
CoexpressionGSE2770_UNTREATED_VS_ACT_CD4_TCELL_6H_DN

TTC3 PPIP5K1 CEP290

5.26e-04200213M6018
CoexpressionPARK_HSC_AND_MULTIPOTENT_PROGENITORS

TTC3 SNX5

5.93e-0445212M1456
CoexpressionDAUER_STAT3_TARGETS_UP

C3 THBS1

6.74e-0448212M12391
CoexpressionAtlasfacebase_RNAseq_e10.5_NeuroEpith_central_2500_K4

ESCO2 FANCM TTC3 SLIT2 SCUBE1 LIN54 SLIT1 CEP290 PLCE1

2.73e-061370219facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500

FANCM LRP2 SLIT2 URB1 MCOLN3 SCUBE1 LIN54 SLIT1 CEP290

3.55e-061414219facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlasfacebase_RNAseq_e8.5_ParaxMesoderm_2500_K1

LRP2 SCUBE1 SLIT1

4.06e-0632213facebase_RNAseq_e8.5_ParaxMesoderm_2500_K1
CoexpressionAtlasfacebase_RNAseq_e9.5_MaxArch_2500_K1

LRP2 MCOLN3 SLIT1

4.56e-0571213facebase_RNAseq_e9.5_MaxArch_2500_K1
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3

TTC3 LRP2 SLIT2 LRP1B NID2 SCUBE1 SLIT1

5.81e-051094217ratio_EB_vs_SC_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K0

LRP2 MCOLN3 SCUBE1

1.59e-04108213facebase_RNAseq_e10.5_Emin_MedNas_2500_K0
CoexpressionAtlasfacebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500

FANCM LRP2 MCOLN3 SCUBE1 SLIT1 CEP290 SNX5

2.15e-041347217facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000

FANCM LRP2 SLIT2 PPIP5K1 SCUBE1 CEP290

2.94e-04986216Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

FANCM SLIT2 PPIP5K1 SCUBE1

3.08e-04339214Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K3
CoexpressionAtlasfacebase_RNAseq_e8.5_ParaxMesoderm_2500

FANCM LRP2 NID2 MCOLN3 SCUBE1 SLIT1 SNX5

3.10e-041429217facebase_RNAseq_e8.5_ParaxMesoderm_2500
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 C3 SLIT1 PLCE1

8.36e-07158214e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 C3 SLIT1 PLCE1

8.36e-07158214d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP2 NID2 C3 PLCE1

1.04e-06167214351f8de1fbdf742ac74f9099b254d515ab539bb2
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP2 NID2 C3 PLCE1

1.04e-06167214c042d6cdddd0e1ddef1e3ac6f4fe23151127b0f2
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

LRP2 NID2 C3 PLCE1

1.17e-0617221436a96714a0eb6ac438648135336c9791881ddadb
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NID2 C3 THBS1 PLCE1

1.74e-061902144f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLIT2 LRP1B C3 SCUBE1

1.82e-0619221411867f30f0b420c18cb0b34d3990237aa737a0e8
ToppCellLA|World / Chamber and Cluster_Paper

LRP2 SLIT2 LRP1B C3

1.86e-06193214d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 C3 THBS1 PLCE1

1.89e-061942141374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 C3 THBS1 PLCE1

1.97e-06196214b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 C3 THBS1 PLCE1

1.97e-06196214787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SLIT2 NID2 C3 THBS1

2.10e-06199214ba586690f88fd051f449753bfe7603a2cb431782
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 C3 THBS1 PLCE1

2.10e-06199214c972d3036151403f26fa9d6271520639c281ab84
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 C3 THBS1 PLCE1

2.10e-06199214b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SLIT2 NID2 C3 THBS1

2.10e-0619921438ed3bc7daa993d9edcf3e7834597ebb06dd24f8
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SLIT2 NID2 C3 THBS1

2.10e-0619921406a7d874ff7c4616577f6e59d3118717a8c47c00
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

SLIT2 NID2 C3 THBS1

2.10e-06199214fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SLIT2 NID2 C3 THBS1

2.10e-061992148b86c69aaf60feff53aa782559cfece7342a23de
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts|LPS_only / Treatment groups by lineage, cell group, cell type

SLIT2 NID2 C3 THBS1

2.10e-061992141a0add79f4e34078b3475eb11c85a4234bda197c
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

SLIT2 NID2 C3 THBS1

2.10e-06199214211c3a08f2d484ab7a3368006767289088f0d957
ToppCelldroplet-Lung-1m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C3 THBS1 EIF2AK4

2.88e-05128213376102331d79010c1b2ce26e6ab0134c7b8a4ec3
ToppCellLPS-antiTNF-Stromal_mesenchymal-Fibroblasts-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPIP5K1 SCUBE1 LIN54

4.71e-05151213f13a117ae26ae525da4f3e837d8f204d00dc6ee3
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C3 EIF2AK4 SLIT1

5.81e-0516221356f1789e69a6cb29956e46aba92b290847327c1f
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LRP2 SLIT2 LIN54

6.25e-05166213f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NID2 C3 PLCE1

6.36e-05167213d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NID2 C3 PLCE1

6.36e-051672137abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 C3 COMP

6.47e-051682134b2d29a7843bf45922038c093ca7ec0600756adc
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP2 NID2 PLCE1

6.47e-05168213a086c306be430adf0632ba53e98cd8014d2de330
ToppCell367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|367C / Donor, Lineage, Cell class and subclass (all cells)

SLIT2 C3 COMP

6.59e-0516921347fd4adfe54777e69a0fabf8bd34f26223f63275
ToppCell367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|367C / Donor, Lineage, Cell class and subclass (all cells)

SLIT2 C3 COMP

6.59e-05169213e09259d62cd3e42f0919f231ed1164db59b0b6c3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 C3 COMP

6.82e-051712135d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1B URB1 COMP

6.82e-051712133ad4f138d9570500cfb4423a2be16bb7d1cacbf8
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 MCOLN3 LIN54

6.82e-05171213845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-like-AT2_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1B URB1 COMP

6.82e-05171213ca2775a17b5c339c480a963953b6fa2b0731f24d
ToppCellfacs-Trachea-nan-24m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 SCUBE1 COMP

7.06e-051732132226505610af1becc253d0a5550627144ef0ed6b
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NID2 C3 PLCE1

7.06e-051732133725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NID2 C3 PLCE1

7.06e-05173213ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 LRP1B C3

7.06e-0517321366f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 LRP1B C3

7.06e-05173213649b08a409095592cccf31883be69c754411280d
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCOLN3 SCUBE1 COMP

7.31e-05175213f1394aacc8a94ca555dd19aaed5a18da99c6bf40
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MCOLN3 SCUBE1 COMP

7.31e-051752137bf1194d93fbe2dbf9d953e0a32b2a6d88251ed1
ToppCell(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells|World / Stress and Cell class

SLIT2 NID2 C3

7.43e-05176213ce2c32b5ce0da848eb4da35ce4d215cdf74d9113
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THBS1 SCUBE1 COMP

7.43e-0517621377c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

LRP2 LRP1B C3

7.43e-0517621336f77d878a53b30465b0dea8333a3865dba75613
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SLIT2 LRP1B C3

7.43e-051762132e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

SLIT2 LRP1B C3

7.43e-05176213f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCellP28-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NID2 PLCE1 COMP

7.56e-05177213e96a7e4544710aaab8bd2800ecff9667880a8bf4
ToppCellP28-Endothelial-lymphatic_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NID2 PLCE1 COMP

7.56e-051772136e330aa3c87fd640526b746a9deb3b2250d2518c
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP2 C3 PLCE1

7.68e-05178213c413861148129be1ee94f2ceb5999840217eebe5
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP2 C3 PLCE1

7.68e-051782131e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP2 C3 PLCE1

7.68e-05178213bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

NID2 C3 PLCE1

7.81e-05179213e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellfacs-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 LRP1B COMP

7.94e-0518021372310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP2 C3 PLCE1

8.07e-051812133f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP2 C3 PLCE1

8.07e-05181213330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 LRP1B PLCE1

8.48e-05184213ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 LRP1B PLCE1

8.48e-051842132cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 LRP1B PLCE1

8.48e-051842132b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3 THBS1 COMP

8.48e-05184213c9d7ec17cc5b7ba1b1e721ca392746e8f4a3d41f
ToppCellMesenchymal_cells-Chondrocytes|World / Lineage and Cell class

NID2 THBS1 COMP

8.48e-051842131e03f9f08de5ad4d45388a95afad9f23ff0d0e28
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 PLCE1 COMP

8.61e-051852133a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCelldroplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 PLCE1 COMP

8.61e-05185213224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1B C3 THBS1

8.75e-051862137582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 THBS1 PLCE1

9.03e-05188213874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 THBS1 PLCE1

9.03e-05188213b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCellLV-14._Fibroblast_III|World / Chamber and Cluster_Paper

TTC3 SLIT2 THBS1

9.18e-051892133922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NID2 PLCE1 COMP

9.32e-05190213a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

SLIT2 NID2 C3

9.32e-051902137dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLIT2 LRP1B PLCE1

9.32e-051902137986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NID2 PLCE1 COMP

9.32e-0519021357c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NID2 PLCE1 COMP

9.32e-05190213f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCell5'-Adult-LymphNode-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NID2 C3 THBS1

9.47e-05191213054e9a79bd1486fd812bc7418fb091664fe3a646
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3 THBS1 COMP

9.47e-051912131b26056df078674f37a6c06f6256b30cfcec21a7
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT2 NID2 THBS1

9.62e-05192213ac1477433704573f95111eee6263b93668d2845e
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NID2 C3 THBS1

9.62e-051922139479e9859140ba98abfe88414de0b28fc2bf43b7
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESCO2 NID2 THBS1

9.62e-05192213a42aed9e563f5f4af029b8804c104f11ad227a8f
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NID2 C3 THBS1

9.62e-05192213d7faa993f68e530ad55185505384ae155d36c222
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLIT2 NID2 C3

9.62e-05192213e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells|(0)_Normal/No_Treatment / Stress and Cell class

SLIT2 NID2 C3

9.62e-051922137a2ad0bdae647b88e799e62767605f2f3c5a426f
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT2 NID2 THBS1

9.62e-051922138937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLIT2 C3 COMP

9.62e-05192213c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCelldroplet-Kidney-nan-3m-Epithelial-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 THBS1 PLCE1

9.62e-051922138b625c22dda23c99654c82c529a1233e99e71b54
ToppCell(3)_Chondrocytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

NID2 THBS1 COMP

9.62e-051922135d2b4830d025d3dbdf5623ce1c28d1036e1984a8
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT2 NID2 THBS1

9.62e-05192213e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLIT2 C3 THBS1

9.76e-05193213261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

C3 THBS1 PLCE1

9.76e-05193213adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

SLIT2 C3 THBS1

9.91e-05194213d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellRA|World / Chamber and Cluster_Paper

THBS1 MCOLN3 PLCE1

9.91e-0519421308f0afbb68a63150fbe107a5337299081c3f69e4
ToppCellLA-14._Fibroblast_III|World / Chamber and Cluster_Paper

SLIT2 C3 THBS1

9.91e-05194213803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCellLV-14._Fibroblast_III|LV / Chamber and Cluster_Paper

TTC3 SLIT2 THBS1

9.91e-05194213927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SLIT2 NID2 PLCE1

9.91e-051942135f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3 THBS1 COMP

1.01e-04195213d2c9c58b46bf96f9a536e177b995e340b55c6750
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLIT2 C3 COMP

1.01e-041952131236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCellASK428-Mesenchymal|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

SLIT2 THBS1 COMP

1.01e-041952132b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCellASK428-Mesenchymal-Fibroblast|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

SLIT2 THBS1 COMP

1.01e-04195213c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 THBS1 PLCE1

1.02e-0419621334e79918a448f6c19b87e1b1ce13c012b24be1f8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 C3 THBS1

1.02e-041962133cb74f1a333a82cac2b459f2f1517e2acf22b5fd
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3 THBS1 COMP

1.02e-0419621361bee32ca299219f31a30b57124e44e85b798e9f
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 THBS1 PLCE1

1.02e-041962138f82e01ca50aa4cd6149547505b4474a02fad618
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3 THBS1 COMP

1.02e-04196213fcb275746bf51269ed8ba4cf93edb054a45f1ccd
DrugGlutethimide, para-amino [125-84-8]; Down 200; 17.2uM; HL60; HT_HG-U133A

LRP2 THBS1 URB1 CEP290

2.84e-051962142390_DN
DrugVerteporfin [129497-78-5]; Up 200; 2.8uM; HL60; HT_HG-U133A

SLIT2 THBS1 URB1 MCOLN3

2.84e-051962146133_UP
Drugvinylidene chloride

ESCO2 LRP2 SLIT2 NID2 C3 MCOLN3 SNX5 PLCE1

2.89e-051475218ctd:C029297
DrugSpiramycin [8025-81-8]; Up 200; 4.8uM; MCF7; HT_HG-U133A

LRP2 C3 THBS1 MCOLN3

2.96e-051982143419_UP
DrugProcaine hydrochloride [51-05-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A

LRP2 SLIT2 C3 URB1

3.08e-052002141674_UP
Drug2-(3-guanidinophenyl)-2-[[1-(hydrocinnamoylamino)-2-methyl-propyl]-hydroxy-phosphoryl]oxy-acetic acid

C3 COMP

6.28e-0513212CID010310938
Drugdiethyl malate

C3 THBS1 COMP

6.59e-0586213ctd:C058705
Drugpyrachlostrobin

LRP2 NID2 C3 THBS1 SCUBE1 PLCE1

6.88e-05811216ctd:C513428
Diseasecystic kidney disease (implicated_via_orthology)

SLIT2 CEP290

2.16e-0510212DOID:2975 (implicated_via_orthology)
Diseasefunctional brain measurement, language measurement

THBS1 PLCE1

1.80e-0428212EFO_0007797, EFO_0007849
Diseasepack-years measurement, systolic blood pressure

LRP2 LRP1B

2.67e-0434212EFO_0006335, EFO_0006526
Diseasevisceral heterotaxy (implicated_via_orthology)

SLIT2 CEP290

3.16e-0437212DOID:0050545 (implicated_via_orthology)
Diseaseoptic disc size measurement

LRP2 LRP1B PLCE1

4.01e-04205213EFO_0004832
Diseasediabetic retinopathy (biomarker_via_orthology)

SLIT2 THBS1

4.69e-0445212DOID:8947 (biomarker_via_orthology)
Diseaselung adenocarcinoma (is_implicated_in)

ESCO2 LRP1B

5.56e-0449212DOID:3910 (is_implicated_in)
DiseaseCOVID-19 (is_marker_for)

C3 THBS1

9.18e-0463212DOID:0080600 (is_marker_for)
Diseaserheumatoid arthritis (is_marker_for)

ESCO2 C3

1.10e-0369212DOID:7148 (is_marker_for)
Diseasemigraine disorder, endometriosis

LRP1B PLCE1

1.23e-0373212EFO_0001065, MONDO_0005277

Protein segments in the cluster

PeptideGeneStartEntry
QNQDEDCNEKNGCHE

EIF2AK4

771

Q9P2K8
DACDNCRSQKNDDQK

COMP

346

P49747
ECQDEENQKQCQDLG

C3

1636

P01024
NQNIDCADASDEKNC

LRP1B

2611

Q9NZR2
CTNCYNNLEHENERQ

LIN54

551

Q6MZP7
CSSHEEENRCNFNQQ

MCOLN3

11

Q8TDD5
CDCDVHKHNQNENLV

FANCM

1081

Q8IYD8
QHVKAECSQCSNNES

MORC3

791

Q14149
DEDKRHQCQNQNCSD

LRP2

2936

P98164
NAANKETCEHNHRQC

NID2

481

Q14112
SDDHCQREQELQKEN

CEP290

2051

O15078
VEKENNCHSAENNSN

ESCO2

176

Q56NI9
DGHNCLDVDECQDNN

SCUBE1

111

Q8IWY4
AKNCDNKNEQLQCDH

PLCE1

241

Q9P212
NKNEQLQCDHCDTLN

PLCE1

246

Q9P212
VHCEQLDAQNQQRCE

URB1

966

O60287
CDNNQDIDEDGHQNN

THBS1

856

P07996
SNRNDEHCGNSNNKC

TTC3

1431

P53804
DFDDCQDNKCKNGAH

SLIT2

1076

O94813
AHQQECCQKFEQLSE

SNX5

341

Q9Y5X3
SENQDDCRDHRCQNG

SLIT1

1081

O75093
SQQCQENHDNGNHTC

PPIP5K1

1286

Q6PFW1