Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

EEF1B2 NET1 IQSEC1 ARHGEF17 PLEKHG5 MADD

3.09e-04231796GO:0005085
GeneOntologyMolecularFunctionprotein serine kinase activity

GAK TTBK1 MAST4 SPEG MINK1 PLK3 WNK4

5.84e-04363797GO:0106310
GeneOntologyMolecularFunctionprotein kinase activity

GAK TTBK1 CSF1R MAST4 SPEG MINK1 IRAK2 PLK3 WNK4

5.95e-04600799GO:0004672
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

EEF1B2 RAP1GAP NET1 IQSEC1 ARHGEF17 PLEKHG5 TBC1D17 MADD

8.79e-04507798GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

EEF1B2 RAP1GAP NET1 IQSEC1 ARHGEF17 PLEKHG5 TBC1D17 MADD

8.79e-04507798GO:0030695
DomainPROTEIN_KINASE_ATP

GAK TTBK1 CSF1R MAST4 SPEG MINK1 IRAK2 PLK3 WNK4

1.00e-04459769PS00107
DomainSer/Thr_kinase_AS

GAK TTBK1 MAST4 SPEG MINK1 IRAK2 PLK3 WNK4

1.00e-04357768IPR008271
DomainPROTEIN_KINASE_ST

GAK TTBK1 MAST4 SPEG MINK1 IRAK2 PLK3 WNK4

1.10e-04362768PS00108
DomainPkinase

GAK TTBK1 MAST4 SPEG MINK1 IRAK2 PLK3 WNK4

1.57e-04381768PF00069
DomainProt_kinase_dom

GAK TTBK1 CSF1R MAST4 SPEG MINK1 IRAK2 PLK3 WNK4

1.61e-04489769IPR000719
DomainPROTEIN_KINASE_DOM

GAK TTBK1 CSF1R MAST4 SPEG MINK1 IRAK2 PLK3 WNK4

1.72e-04493769PS50011
DomainKinase-like_dom

GAK TTBK1 CSF1R MAST4 SPEG MINK1 IRAK2 PLK3 WNK4

3.46e-04542769IPR011009
DomainS_TKc

GAK TTBK1 MAST4 SPEG MINK1 PLK3 WNK4

6.41e-04359767SM00220
Domain-

NET1 PLEKHM2 IQSEC1 IRS1 ARHGEF17 PLEKHG5 FAM43A

1.06e-033917672.30.29.30
DomainPH_dom-like

NET1 PLEKHM2 IQSEC1 IRS1 ARHGEF17 PLEKHG5 FAM43A

1.73e-03426767IPR011993
DomainDH_1

NET1 ARHGEF17 PLEKHG5

2.16e-0363763PS00741
DomainRhoGEF

NET1 ARHGEF17 PLEKHG5

2.68e-0368763SM00325
DomainRhoGEF

NET1 ARHGEF17 PLEKHG5

2.91e-0370763PF00621
DomainDH_2

NET1 ARHGEF17 PLEKHG5

2.91e-0370763PS50010
DomainDH-domain

NET1 ARHGEF17 PLEKHG5

3.03e-0371763IPR000219
Domain-

NET1 ARHGEF17 PLEKHG5

3.03e-03717631.20.900.10
DomainPH

NET1 PLEKHM2 IQSEC1 IRS1 PLEKHG5

5.51e-03278765SM00233
DomainPH_DOMAIN

NET1 PLEKHM2 IQSEC1 IRS1 PLEKHG5

5.59e-03279765PS50003
DomainPH_domain

NET1 PLEKHM2 IQSEC1 IRS1 PLEKHG5

5.68e-03280765IPR001849
DomainDeath_domain

IRAK2 MADD

1.04e-0238762IPR000488
DomainDEATH_DOMAIN

IRAK2 MADD

1.04e-0238762PS50017
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SNX30 NACA2 ANKS6 PWWP2B KIAA0513 PLEKHM2 GLI1 SPEG PPP1R15B UBR4 DIP2C IRS1 FBXL19 PLEKHG5 PLK3 KIFC2 TBC1D17 MADD HR

4.32e-121105791935748872
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

STIM1 RAP1GAP MAST4 ALMS1 NET1 KIAA0232 MINK1 IQSEC1 BOD1L1 IRS1 MTCL1 ARHGEF17 WNK4 MADD

8.20e-09861791436931259
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KIAA0513 PLEKHM2 SPEG KIAA0232 PACS2 BOD1L1 MTCL1 ARHGEF17 MADD

3.77e-0740779912693553
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PRUNE2 MAST4 ALMS1 ARHGEF17 MADD

4.10e-061047959205841
Pubmed

Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions.

ZBTB20 GLI1 WNK4

1.46e-052179329659575
Pubmed

Clinical significance of the TNF-α receptors, TNFRSF2 and TNFRSF9, on cell migration molecules Fascin-1 and Versican in acute leukemia.

VCAN FSCN1

1.53e-05379229861382
Pubmed

Evolutionarily conserved binding of translationally controlled tumor protein to eukaryotic elongation factor 1B.

TPT1 EEF1B2

1.53e-05379225635048
Pubmed

The chemotherapeutic agent DMXAA as a unique IRF3-dependent type-2 vaccine adjuvant.

IRF3 IFNAR2

1.53e-05379223555875
Pubmed

Foot-and-mouth disease virus infection suppresses autophagy and NF-кB antiviral responses via degradation of ATG5-ATG12 by 3Cpro.

ATG12 IRF3

1.53e-05379228102839
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

ALMS1 PLEKHM2 UBR4 IQSEC1 KIRREL2 SLC45A4

1.57e-0523379637704626
Pubmed

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation.

IRAK2 IRF3

3.05e-05479218636090
Pubmed

Human T cell lymphotropic virus 1 manipulates interferon regulatory signals by controlling the TAK1-IRF3 and IRF4 pathways.

NR2C2 IRF3

3.05e-05479219955181
Pubmed

Translationally controlled tumor protein acts as a guanine nucleotide dissociation inhibitor on the translation elongation factor eEF1A.

TPT1 EEF1B2

3.05e-05479214623968
Pubmed

Identification of a conserved family of Meis1-related homeobox genes.

MEIS3 MEIS3P1

3.05e-0547929049632
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

NET1 GLI1 VCAN AEBP2 SERINC3 BOD1L1 TACC2 QSER1 KIFC2 MADD BRWD1

3.34e-051084791111544199
Pubmed

IFITM3 and type I interferons are important for the control of influenza A virus replication in murine macrophages.

IRF3 IFNAR2

5.07e-05579231731106
Pubmed

Species-dependent role of type I IFNs and IL-12 in the CTL response induced by humanized CpG complexed with β-glucan.

IRF3 IFNAR2

5.07e-05579226786557
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

UBXN7 IQSEC1 MTCL1 PLEKHG5

8.52e-051017949872452
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

EEF1B2 GAK RAP1GAP VCAN MINK1 AFG3L2 IQSEC1 PACS2 FSCN1 ARHGEF17 PLEKHG5 MADD

8.98e-051431791237142655
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

LIG3 TRIR ALMS1 AFG3L2 AEBP2 BOD1L1 FSCN1

9.74e-0546979727634302
Pubmed

TLR9 and STING agonists synergistically induce innate and adaptive type-II IFN.

IRF3 IFNAR2

1.06e-04779225529558
Pubmed

Two distinct ontogenies confer heterogeneity to mouse brain microglia.

HOXB8 CSF1R

1.06e-04779229973370
Pubmed

A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.

IRF3 IFNAR2

1.06e-04779216286919
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

LIG3 RAP1GAP MINK1 AFG3L2 QSER1 TBC1D17 MADD HR

1.16e-0465079838777146
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PRUNE2 SNX30 PWWP2B ZBTB20 FAM53A KIAA0232 MINK1 DIP2C BOD1L1 MACROH2A2 MEIS3 QSER1

1.30e-041489791228611215
Pubmed

UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy.

ATG12 UBR4

1.41e-04879223431188
Pubmed

Neural Hedgehog signaling maintains stem cell renewal in the sensory touch dome epithelium.

GLI1 HR

1.41e-04879226015562
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

LIG3 EEF1B2 NR2C2 RRP1B MACROH2A2 FSCN1

1.47e-0434979625665578
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

HOXB8 ZBTB20 GLI1 DIP2C IRF3 MEIS3 FBXL19 SOWAHC HR

1.68e-0487779920211142
Pubmed

ZBTB20 is essential for cochlear maturation and hearing in mice.

ZBTB20 EMILIN2 WNK4

1.70e-044779337279265
Pubmed

DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169.

CNOT11 KIAA0232 IRS1 ARHGEF17

1.77e-0412279430773093
Pubmed

PIKES Analysis Reveals Response to Degraders and Key Regulatory Mechanisms of the CRL4 Network.

UBXN7 DCAF4 BRWD1

1.93e-044979331973889
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

NR2C2 ZBTB20 CSF1R MINK1 IRAK2 WNK4

2.07e-0437279622939624
Pubmed

Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice.

VCAN MARCKSL1

2.27e-04107929184108
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

TPT1 RAP1GAP IRF3 MEIS3 PLEKHG5 TBC1D17 MADD BRWD1 IFNAR2

2.49e-0492579928986522
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

STIM1 EEF1B2 KIAA0513 MINK1 UBR4 AFG3L2 IQSEC1 TACC2 MARCKSL1 MADD

2.53e-041139791036417873
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

LIG3 EEF1B2 GAK TRIR ALMS1 ATF7IP AFG3L2 BOD1L1 TACC2

2.68e-0493479933916271
Pubmed

DNA released from dying host cells mediates aluminum adjuvant activity.

IRF3 IFNAR2

2.76e-041179221765404
Pubmed

Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development.

GLI1 VCAN

2.76e-041179238750698
Pubmed

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.

TPT1 EEF1B2 RAP1GAP KIAA0513 AFG3L2 MACROH2A2 FSCN1

2.82e-0455879735063084
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

LIG3 NR2C2 ATF7IP AEBP2 FSCN1 SOWAHC

2.97e-0439879635016035
Pubmed

Protein phosphatase 1γ isoforms linked interactions in the brain.

RRP1B PPP1R15B TACC2

3.02e-045779323080069
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

STIM1 ANKS6 PLEKHM2 SCARF2 ATF7IP PPP1R15B MINK1 MARCKSL1

3.86e-0477779835844135
Pubmed

UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.

UBR4 UBXN7 BRWD1

3.87e-046279318775313
Pubmed

Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial.

IRF3 IFNAR2

3.91e-041379219434718
Pubmed

Cutting Edge: Distinct Regulatory Mechanisms Control Proinflammatory Cytokines IL-18 and IL-1β.

IRF3 IFNAR2

3.91e-041379228468974
Pubmed

Gli2 influences proliferation in the developing lung through regulation of cyclin expression.

GLI1 VCAN

3.91e-041379219574535
Pubmed

Genome-wide chromatin accessibility and transcriptome profiling show minimal epigenome changes and coordinated transcriptional dysregulation of hedgehog signaling in Danforth's short tail mice.

GLI1 KIRREL2

3.91e-041379230380057
Pubmed

Range of HOX/TALE superclass associations and protein domain requirements for HOXA13:MEIS interaction.

HOXB8 MEIS3

4.55e-041479215617687
Pubmed

Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity.

HOXB8 GLI1

4.55e-04147929834182
Pubmed

Adaptor SH3BGRL drives autophagy-mediated chemoresistance through promoting PIK3C3 translation and ATG12 stability in breast cancers.

EEF1B2 ATG12

4.55e-041479234870550
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

LIG3 NR2C2 TRIR RRP1B BOD1L1 QSER1 BRWD1

4.71e-0460879736089195
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

LIG3 NR2C2 TRIR RRP1B BOD1L1

4.75e-0428379530585729
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

TPT1 LIG3 EEF1B2 TRIR UBR4 UBXN7 BOD1L1 QSER1 FSCN1

4.87e-04101479932416067
Pubmed

Rap2A links intestinal cell polarity to brush border formation.

RAP1GAP MINK1

5.25e-041579222797597
Pubmed

The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway.

ALMS1 GLI1

5.25e-041579226035863
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

STIM1 NR2C2 GAK RRP1B PPP1R15B MINK1 UBR4 AFG3L2 MARCKSL1 FSCN1 TBC1D17

5.26e-041487791133957083
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

CNOT11 RAP1GAP ANKS6 ATG12 IQSEC1 IRF3 SOWAHC TBC1D17 MADD

5.75e-04103879926673895
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

LIG3 NR2C2 KIAA0513 GLI1 UBR4 IRF3 MACROH2A2 QSER1

7.34e-0485779825609649
Pubmed

ILK modulates epithelial polarity and matrix formation in hair follicles.

GLI1 VCAN

8.50e-041979224371086
Pubmed

Hydroxypropyl-β-cyclodextrin spikes local inflammation that induces Th2 cell and T follicular helper cell responses to the coadministered antigen.

IRF3 IFNAR2

8.50e-041979225681338
Pubmed

Cancer Stem Cells Regulate Cancer-Associated Fibroblasts via Activation of Hedgehog Signaling in Mammary Gland Tumors.

GLI1 VCAN

8.50e-041979228202523
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PRUNE2 RAP1GAP TTBK1 ALMS1 DIP2C SLC45A4

9.13e-0449379615368895
Pubmed

Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion.

IRF3 IFNAR2

9.43e-042079232150572
Pubmed

Math1 target genes are enriched with evolutionarily conserved clustered E-box binding sites.

MEIS3 HR

9.43e-042079216679559
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

STIM1 SNX30 ANKS6 PLEKHM2 PPP1R15B MADD

1.02e-0350479634432599
Pubmed

Growth arrest specific gene 1 acts as a region-specific mediator of the Fgf10/Fgf8 regulatory loop in the limb.

HOXB8 GLI1

1.04e-032179212399319
Pubmed

CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia.

CSF1R IRF3 IRS1

1.04e-038779329991678
Pubmed

Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.

GLI1 VCAN

1.25e-032379230814516
Pubmed

CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism.

NR2C2 AEBP2

1.25e-032379231281901
Pubmed

Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome.

HOXB8 MEIS3

1.25e-032379218691704
Pubmed

IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.

IRF3 IFNAR2

1.25e-032379229576451
Pubmed

ADAMTS9-Mediated Extracellular Matrix Dynamics Regulates Umbilical Cord Vascular Smooth Muscle Differentiation and Rotation.

GLI1 VCAN

1.25e-032379226027930
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

STIM1 EEF1B2 CNOT11 TRIR RRP1B UBR4 AFG3L2 TACC2 MTCL1 FSCN1

1.35e-031415791028515276
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

LIG3 UBR4 BRME1 BOD1L1 IRS1 MTCL1 ARHGEF17

1.43e-0373679729676528
Pubmed

Human transcription factor protein interaction networks.

LIG3 NR2C2 CNOT11 ALMS1 RRP1B ATF7IP UBR4 UBXN7 IRF3 QSER1

1.46e-031429791035140242
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

LIG3 EEF1B2 NR2C2 TRIR RRP1B ATF7IP BOD1L1 QSER1

1.46e-0395479836373674
Pubmed

Common variants at ten loci influence QT interval duration in the QTGEN Study.

LIG3 PLEKHG5

1.48e-032579219305408
Pubmed

Age- and stage-specific regulation patterns in the hematopoietic stem cell hierarchy.

STIM1 CSF1R

1.48e-032579211698278
Pubmed

DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity.

MACROH2A2 DCAF4 BRWD1

1.51e-039979334161765
Pubmed

N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.

PWWP2B EMILIN2 BOD1L1 SLC45A4

1.54e-0321779434048709
Pubmed

PTEN identified as important risk factor of chronic obstructive pulmonary disease.

LIG3 CSF1R IRF3 IRS1 IFNAR2

1.65e-0337479519625176
Pubmed

Early mouse caudal development relies on crosstalk between retinoic acid, Shh and Fgf signalling pathways.

HOXB8 GLI1

1.72e-032779219168680
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PRUNE2 ALMS1 KIAA0232 DIP2C

1.75e-0322579412168954
Pubmed

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.

CNOT11 ALMS1 PPP1R15B AFG3L2

1.78e-0322679425900982
Pubmed

Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.

LIG3 CSF1R IRF3 IRS1 IFNAR2

1.78e-0338179518676680
Pubmed

Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.

LIG3 CSF1R IRF3 IRS1 IFNAR2

1.80e-0338279519170196
Pubmed

Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease.

IRF3 IFNAR2

1.85e-032879228410990
Pubmed

Human liver protein map: a reference database established by microsequencing and gel comparison.

TPT1 EEF1B2

1.85e-03287921286669
Pubmed

Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.

IRF3 IFNAR2

1.99e-032979233278357
Pubmed

Expanding the substantial interactome of NEMO using protein microarrays.

TPT1 BRME1 ACBD6

1.99e-0310979320098747
Pubmed

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.

UBR4 FSCN1 SOWAHC TBC1D17

2.05e-0323579428378594
Pubmed

STK40 Is a Pseudokinase that Binds the E3 Ubiquitin Ligase COP1.

KIAA0232 MTCL1

2.27e-033179228089446
Pubmed

ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis.

GLI1 MEIS3

2.27e-033179236445780
InteractionTOP3B interactions

SNX30 LIG3 NACA2 CNOT11 ANKS6 PWWP2B KIAA0513 PLEKHM2 GLI1 SPEG PPP1R15B UBR4 DIP2C IRS1 FBXL19 PLEKHG5 DCAF4 PLK3 KIFC2 TBC1D17 MADD HR

1.71e-0814707722int:TOP3B
InteractionYWHAH interactions

STIM1 RAP1GAP MAST4 ALMS1 NET1 SPEG KIAA0232 MINK1 PACS2 BOD1L1 IRS1 MTCL1 ARHGEF17 PLEKHG5 MADD

1.53e-0511027715int:YWHAH
InteractionYWHAG interactions

STIM1 RAP1GAP TTBK1 MAST4 ALMS1 NET1 SPEG KIAA0232 MINK1 IQSEC1 PACS2 BOD1L1 IRS1 MTCL1 ARHGEF17 PLEKHG5

1.60e-0512487716int:YWHAG
GeneFamilyWD repeat domain containing|DDB1 and CUL4 associated factors

DCAF4 BRWD1

1.03e-0318482498
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

NET1 PLEKHM2 IRS1 PLEKHG5

2.15e-03206484682
GeneFamilyTALE class homeoboxes and pseudogenes

MEIS3 MEIS3P1

2.15e-0326482526
GeneFamilyAutophagy related

SNX30 ATG12

3.46e-03334821022
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SPEG VCAN DIP2C TACC2 IRS1 MEIS3 MTCL1

4.00e-08185797e58a009aaf342be019a909747b1895d5987d4daf
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NET1 UBR4 UBXN7 IQSEC1 SERINC3 BOD1L1 MARCKSL1

5.16e-081927971ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellBAL-Severe-cDC_4|Severe / Compartment, Disease Groups and Clusters

NR2C2 ANKS6 VCAN LRP11 DIP2C DCAF4

3.84e-0715879673f66689ef59f71b14cb7141ca5951cc47fe57c1
ToppCelldroplet-Marrow-BM-30m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R ATF7IP KIAA0232 MINK1 UBR4 KIFC2

4.44e-0716279675df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRUNE2 NET1 PLEKHM2 IQSEC1 DIP2C HR

9.35e-071847968fa30789c9d583188667cf375d2218e392dd40bc
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRUNE2 NET1 PLEKHM2 IQSEC1 DIP2C HR

9.65e-071857964bee178ede12f56ba5f5bec44a03dc2a62c50137
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRUNE2 HOXB8 TACC2 FBXL19 WNK4 SLC45A4

9.96e-07186796c116cc9f41971622264434ebe29d18e719b0ae19
ToppCelldroplet-Lung-nan-18m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 NET1 PLEKHM2 IQSEC1 DIP2C HR

1.03e-06187796f0c6e53035b00772377c4d5f761b4d11026b911a
ToppCelldroplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 NET1 PLEKHM2 IQSEC1 DIP2C HR

1.03e-06187796f20e7a1751694390f535ffb27b97e887220f8695
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 GLI1 SPEG TACC2 IRS1 MTCL1

1.06e-06188796293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 RAP1GAP SUSD4 VCAN MACROH2A2 MARCKSL1

1.06e-06188796006db2c2c44971ca9241c582bc89f258c785f5ed
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 RAP1GAP SUSD4 VCAN MACROH2A2 MARCKSL1

1.06e-06188796d0e6fb4a3b3d79d3512b5500062ea285495ae526
ToppCellfacs-Skin-nan-18m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXB8 SCARF2 IQSEC1 MARCKSL1 KIRREL2 HR

1.31e-06195796ba7cb80deb872c9184769f0dd57855c3c6a432bf
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-4|TCGA-Liver / Sample_Type by Project: Shred V9

SNX30 CNOT11 ANKS6 MACROH2A2 SLC45A4

1.27e-051697950a3ba6b5d6cff9d3d7f56046063cfc3a37ae1156
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IQSEC1 FBXL19 WNK4 MADD FAM43A

1.31e-0517079555fe16d98ea284d05fb899888e4569c685644c7b
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAP1GAP MINK1 MARCKSL1 PLEKHG5 WNK4

1.50e-05175795019ea30ac55748463d7917abf3d3f0e804189bfd
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

GLI1 VCAN LRP11 SERINC3 ZNF853

1.63e-05178795edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 RAP1GAP SUSD4 VCAN MARCKSL1

1.72e-05180795fa819df81fca95c2cc602fede635cb03e3f35fad
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 RAP1GAP SUSD4 VCAN MARCKSL1

1.72e-05180795907cd510fd2e21532ce04ba687e8894f7af71f27
ToppCelldroplet-Limb_Muscle-nan-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPT1 EEF1B2 CSF1R VCAN EMILIN2

1.72e-05180795d3d0be136fff5d3e39ecf5a5dbefc1d0d0a6c814
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PRUNE2 SPEG TACC2 IRS1 MTCL1

1.77e-0518179525915e2500430a902db37d79a749ce2990b69810
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP SUSD4 VCAN IRS1 MARCKSL1

1.77e-051817954e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP SUSD4 VCAN IRS1 MARCKSL1

1.77e-05181795ad30c01290fb98adbd0caed301a584761212c977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP SUSD4 VCAN IRS1 MARCKSL1

1.77e-051817953a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 NET1 PLEKHM2 IQSEC1 MADD

1.81e-051827953dec003bad0f3716cf8163861a9d4302a7d6df8c
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

VCAN DIP2C TACC2 IRS1 MEIS3

1.81e-05182795ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCelldroplet-Lung-nan-3m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 NET1 PLEKHM2 IQSEC1 HR

1.86e-05183795ec3c05b9ce1e0fbb720e0dea41f1e28fd3fd878f
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRUNE2 NET1 PLEKHM2 IQSEC1 HR

1.91e-0518479515ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRUNE2 NET1 PLEKHM2 IQSEC1 HR

1.91e-05184795bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCelldroplet-Lung-nan-3m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 NET1 PLEKHM2 IQSEC1 HR

1.91e-051847953261d767d5e3d9e9fbac22ad73ca14e44beed89c
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 GLI1 SPEG IRS1 MTCL1

2.01e-051867956add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCelldroplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 NET1 PLEKHM2 IQSEC1 HR

2.01e-05186795f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP SUSD4 MAST4 IRS1 WNK4

2.01e-051867951850583d23903d08226aeb0edb3e07b0994330e4
ToppCelldroplet-Lung-nan-21m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 NET1 PLEKHM2 IQSEC1 HR

2.01e-051867958f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP SUSD4 MAST4 IRS1 WNK4

2.01e-051867954dafc215c42e7949f932a3627359c107943b5d6b
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 GLI1 SPEG IRS1 MTCL1

2.12e-051887953177b2c1723268d330d3e9f24f9e24492ace6286
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SPEG IRS1 MARCKSL1 MTCL1 HR

2.12e-05188795c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PRUNE2 SPEG TACC2 IRS1 MTCL1

2.12e-051887954d1e5f85342ae550086609d7680e32730b78b5d2
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRUNE2 NET1 IQSEC1 DIP2C HR

2.17e-0518979598f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRUNE2 NET1 IQSEC1 DIP2C HR

2.17e-05189795f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCellfacs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD4 SERINC3 MARCKSL1 FSCN1 FAM43A

2.29e-0519179548823a97c38263f2c6e58348214f5b62773a6368
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD4 SERINC3 MARCKSL1 FSCN1 FAM43A

2.29e-051917950eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAST4 IQSEC1 SERINC3 FAM43A BRWD1

2.34e-051927952de242d81dc085ae734eb7d1f091af9a542e0866
ToppCell11.5-Distal|11.5 / Age, Tissue, Lineage and Cell class

TPT1 HOXB8 VCAN MARCKSL1 FSCN1

2.34e-05192795169b9ee2377beb9e4ad35bc82bb7a3dafe8f05b6
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAST4 IQSEC1 SERINC3 FAM43A BRWD1

2.34e-05192795ba2a683472a8b785dbf666dc6e94356d879486c3
ToppCellfacs-Bladder-nan-3m|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIDT2 ZBTB20 SCARF2 IQSEC1 SERINC3

2.59e-0519679544f5b1b474399c9316729155f2ea95a82ca66e30
ToppCellcontrol-immature_Neutrophil|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANKS6 KIAA0513 UBR4 PACS2 QSER1

2.59e-05196795e34fd3e7a5b1c22a81fd3208e6d58bdb846d51c4
ToppCellfacs-Bladder-nan-3m-Epithelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIDT2 ZBTB20 SCARF2 IQSEC1 SERINC3

2.59e-05196795c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
ToppCellBAL-Mild-cDC_10|Mild / Compartment, Disease Groups and Clusters

NET1 MINK1 MACROH2A2 MARCKSL1 FSCN1

2.65e-05197795c0550d41dd5619b369b590f3d6a61154dd7b2cab
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

PRUNE2 GLI1 TACC2 IRS1 MEIS3

2.85e-05200795c5e051f1aac8dda376c342a9932785a23450e073
ToppCellfacs-Brain_Non-Myeloid-Hippocampus|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAST4 PACS2 SERINC3 MARCKSL1 FSCN1

2.85e-05200795fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCellproximal-mesenchymal-Fibromyocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRUNE2 HOXB8 GLI1 SPEG IRS1

2.85e-0520079537d9f46f727a31e8e94e348e4ddd71a2125ba01a
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

PRUNE2 GLI1 VCAN IRS1 MEIS3

2.85e-052007959d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCellproximal-3-mesenchymal-Fibromyocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRUNE2 HOXB8 GLI1 SPEG IRS1

2.85e-05200795ed6fbe61a04d29b105054f7058abe7469314b304
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PRUNE2 GLI1 TACC2 IRS1 MTCL1

2.85e-05200795c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

PRUNE2 RAP1GAP TACC2 IRS1 MTCL1

2.85e-05200795593bf6a7c557437db9a9249a5058a46014179ef6
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAST4 PACS2 SERINC3 MARCKSL1 FSCN1

2.85e-05200795f0c338877e39226a90c4effe12f6501d33542a73
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate|6m / Sample Type, Dataset, Time_group, and Cell type.

TPT1 NACA2 VCAN AEBP2 BOD1L1

2.85e-052007957c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PRUNE2 GLI1 TACC2 IRS1 MTCL1

2.85e-05200795dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCellproximal-mesenchymal-Fibromyocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRUNE2 HOXB8 GLI1 SPEG IRS1

2.85e-0520079549658e1b530de0dad16d45a1112bdf5329bb800d
ToppCellClub-club-1|World / Class top

STIM1 EMILIN2 BRME1

1.21e-045479348f80b20b1c4995a0f7084d31666781dce4009a9
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NACA2 PPP1R15B MEIS3 PLK3

1.26e-041447945e948d4cb913ccd8f82262a1b4d20967aadab3ab
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l8|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATF7IP EMILIN2 IRAK2 MARCKSL1

1.75e-041577945098675f64342c41c5ca3551b24962d10c83e64d
ToppCellmild-Myeloid-CD14_Monocytes_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SIDT2 VCAN EMILIN2 KIRREL2

1.88e-04160794a83568cd8a0b05642bacd43a8ec443e5ce314c4d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNOT11 RRP1B KIRREL2 TBC1D17

1.93e-041617949f02b94e29e60d50e92eaa748ebf0c36d3671bb3
ToppCellfacs-Spleen-nan-3m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R KIAA0513 EMILIN2 FSCN1

1.93e-0416179445591addc765760db6029ac19e80573373d1d917
ToppCellfacs-Spleen-nan-3m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R KIAA0513 EMILIN2 FSCN1

1.93e-041617948741b91a62c9a8ce377ef6533d323b65beb93c63
ToppCellfacs-Spleen-nan-3m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R KIAA0513 EMILIN2 FSCN1

1.93e-041617949cf1dcf0e7ca9e35c46c094a6b78f98d1f6b9276
ToppCellfacs-Marrow-T_cells-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R VCAN EMILIN2 SOWAHC

2.02e-0416379430cd95d4f37bd54c1fde54960cb005db58bdd30c
ToppCellfacs-Marrow-T_cells-18m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R VCAN EMILIN2 SOWAHC

2.02e-04163794ab934cb986495adfc8dbe5a276577f2a8fb6ee03
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRUNE2 CSF1R PACS2 SERINC3

2.12e-0416579447e716ce8dc283d406352c1909e09362fcb9e3a3
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRUNE2 CSF1R PACS2 SERINC3

2.12e-04165794fe2135fdacf3807eb4b5ea5e790febfb8cd54335
ToppCell15-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

PRUNE2 SPEG TACC2 MTCL1

2.12e-04165794531804467601e1ee1f771cffa21501f6d464ae10
ToppCellmild-Myeloid-CD14_Monocytes_3|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CSF1R VCAN EMILIN2 KIRREL2

2.12e-04165794a6547bb2c9c40b4878325da19b9def0ef644fa25
ToppCell356C-Fibroblasts-Fibroblast-D|356C / Donor, Lineage, Cell class and subclass (all cells)

SCARF2 GLI1 MEIS3 HR

2.16e-041667947286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MACROH2A2 MARCKSL1 FSCN1 LRRC43

2.16e-04166794da10d0be6b616199d49dd922591c2901f9681583
ToppCell356C-Fibroblasts-Fibroblast-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

SCARF2 GLI1 MEIS3 HR

2.16e-041667947c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R VCAN EMILIN2 SOWAHC

2.16e-04166794bf6c35c3e67ef4ca98a38926c6f7923ecca0508a
ToppCellfacs-Lung-EPCAM-18m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R VCAN EMILIN2 SOWAHC

2.16e-04166794433128b7d964b32faa0bf437a02facc819ab1405
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 ALMS1 GLI1 KIFC2

2.21e-04167794f5bffa77061baec0ba87bd688a047595f32534db
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

TTBK1 MAST4 DIP2C IRAK2

2.27e-0416879463437b3c3a66f953eaed600965ab193f9cc49da2
ToppCelldroplet-Lung-LUNG-30m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALMS1 AEBP2 MARCKSL1 FSCN1

2.27e-041687940e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCellfacs-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 CSF1R PLEKHM2 EMILIN2

2.27e-041687944ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCell343B-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

NET1 MINK1 MARCKSL1 FSCN1

2.32e-04169794e68e6c24606fd46eca6f86bb63fa86ea17879ae2
ToppCell343B-Myeloid-Dendritic-cDC_activated|343B / Donor, Lineage, Cell class and subclass (all cells)

NET1 MINK1 MARCKSL1 FSCN1

2.32e-041697942098f15a388d019ed7f1d4c209affd5ca2886dcc
ToppCelldroplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANKS6 CSF1R SPEG FSCN1

2.37e-04170794f664c7559e383b37845c123e41a3be316d869ba0
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R VCAN EMILIN2 PACS2

2.37e-04170794a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCelldroplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANKS6 CSF1R SPEG FSCN1

2.37e-041707940272eb1487c2545d4aa06f5d1cd77f823e1441e9
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R VCAN EMILIN2 PACS2

2.37e-04170794ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCellfacs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NET1 AEBP2 MARCKSL1 FSCN1

2.37e-04170794df1a34a69ae404c56f00751a01f52359535f5469
ToppCelldroplet-Marrow-nan-3m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R VCAN EMILIN2 SOWAHC

2.42e-04171794992df143d76f9e7fb1997a8996f61e941f0f9d4f
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

NET1 MACROH2A2 MARCKSL1 FSCN1

2.42e-04171794ce290930385cac35dbd21a5e91cf0f93cf3e99f8
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKS6 CSF1R PLEKHM2 MADD

2.48e-04172794574ebdf36e45222bcd907cd2c2ee7ff50ed4573a
ToppCellfacs-BAT-Fat-3m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R VCAN EMILIN2 SOWAHC

2.48e-041727945f18c3f8eb8b7928901eede44c9b84b3c5efa1a9
ToppCellASK440-Epithelial-Transformed_epithelium|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

SUSD4 ANKS6 BRME1 IRAK2

2.48e-04172794df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKS6 CSF1R PLEKHM2 MADD

2.48e-041727941627fa7035b0e0bbc82a1c0f000d8231254c680a
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R VCAN EMILIN2 SOWAHC

2.53e-04173794807183fc23478da9451906dacd88de4e73112e0d
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R VCAN EMILIN2 SOWAHC

2.53e-041737942e683ec555dc0036875e0f5674dcc5e93ead205d
ToppCellImmune_cells-Monocytes|Immune_cells / Lineage and Cell class

CSF1R EMILIN2 SOWAHC IFNAR2

2.53e-041737943eced40a65453a023a1673658592e7e2a099119b
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SIDT2 VCAN IQSEC1 EMILIN2

2.59e-04174794d5c22b43531414951666ee7542a66ed9380e2d14
DrugAH6809; Up 200; 1uM; PC3; HT_HG-U133A

STIM1 LIG3 SIDT2 KIAA0513 PLEKHM2 MINK1 PACS2 HR IFNAR2

2.69e-081997897075_UP
DrugProcyclidine hydrochloride [1508-76-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A

STIM1 LIG3 ALMS1 SPEG DCAF4 PLK3 TBC1D17

4.80e-061957874817_UP
DrugAnabasine [494-52-0]; Up 200; 24.6uM; MCF7; HT_HG-U133A

CSF1R PLEKHM2 MINK1 FSCN1 ARHGEF17 DCAF4 HR

4.96e-061967876774_UP
Diseaseintellectual disability (implicated_via_orthology)

ATF7IP UBR4 BOD1L1 IRS1

4.30e-0575764DOID:1059 (implicated_via_orthology)
Diseaserestless legs syndrome (implicated_via_orthology)

MEIS3 MEIS3P1

1.81e-048762DOID:0050425 (implicated_via_orthology)
Diseasegastrointestinal stromal tumor (is_implicated_in)

STIM1 CSF1R

3.55e-0411762DOID:9253 (is_implicated_in)
DiseaseMalignant neoplasm of breast

EEF1B2 RAP1GAP CSF1R NET1 SCARF2 GLI1 UBR4 DIP2C BOD1L1 TACC2

4.23e-0410747610C0006142
DiseaseAutosomal Recessive Centronuclear Myopathy

STIM1 SPEG

6.73e-0415762C3645536
Diseasealpha-L-iduronidase measurement

GAK FAM53A

8.68e-0417762EFO_0020139
Diseaseleukemia (implicated_via_orthology)

MEIS3 MEIS3P1

1.09e-0319762DOID:1240 (implicated_via_orthology)
Diseasenose morphology measurement, mouth morphology measurement

MEIS3 MEIS3P1

1.33e-0321762EFO_0007843, EFO_0007955
Diseasechronic obstructive pulmonary disease

SCARF2 SPEG AEBP2 MTCL1 QSER1 ARHGEF17 DCAF4

1.98e-03688767EFO_0000341
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

ALMS1 IRS1 MADD

2.55e-03105763DOID:9352 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
GDDESPSTSSGTAGT

DCAF4

46

Q8WV16
SSSGGGEEESSAESL

AEBP2

111

Q6ZN18
GEEESSAESLVGSSG

AEBP2

116

Q6ZN18
SGSSSIPITEGSGEA

VCAN

1631

P13611
EGTGSLDEDTSLPEG

AFG3L2

761

Q9Y4W6
SNSTSEDGPGDGFTI

MACROH2A2

171

Q9P0M6
SESEDGGGSSVDSLA

ALMS1

2466

Q8TCU4
ITGDSGGELSSGDDS

ACBD6

11

Q9BR61
AAGGEGLTDVSPETT

ATG12

16

O94817
SSGTSLSEDEAPGEA

FBXL19

336

Q6PCT2
SSSPSLADGIDTSGG

NR2C2

326

P49116
SESEFTLGGDDSGVS

QSER1

1021

Q2KHR3
SSDAESGTGSSDREP

MTCL1

231

Q9Y4B5
GSLGDGASESETTES

KIAA0513

36

O60268
SGLSTEGATGPSADT

NET1

21

Q7Z628
EGATGPSADTSGSEL

NET1

26

Q7Z628
GGGSSSETVGRDDST

ARHGEF17

2041

Q96PE2
TTGPSEDAGGDSLVE

LRP11

366

Q86VZ4
CASEEGGTESSESGS

MADD

126

Q8WXG6
SEGTGSSSNTPEETD

IRAK2

516

O43187
SGVEGEAPSSETGTS

IQSEC1

21

Q6DN90
DTATNSSSEEGPGSG

HR

531

O43593
ISASELSPGGGSESE

KIAA0232

1111

Q92628
ASSTSEETGSEGGGE

KIAA0232

1366

Q92628
DTSVASPSSGGEDED

MEIS3

241

Q99687
AGGSTEDLSSLDEGP

GLI1

471

P08151
SGDSDDAAPSGSGTL

PACS2

691

Q86VP3
VAGDEGSSTTGGSSE

LIG3

841

P49916
VSGSPSDGGFISSDE

IRS1

416

P35568
ESDSDTEAAPRTSGG

IFNAR2

321

P48551
SGLGEEAEGSEQSPS

HOXB8

116

P17481
EGGGDSSASSPTEEE

MARCKSL1

111

P49006
EGPASCTGSEDSSEG

BOD1L1

1801

Q8NFC6
SEVSDEGGSPISSEG

GAK

826

O14976
RSGGSGSSSSELEEE

CSF1R

931

P07333
GCTSLTGETTGESGE

BRME1

386

Q0VDD7
GSDSAVTSSGDTPVD

FSCN1

436

Q16658
PDTSSGSEDEGSVQG

DIP2C

131

Q9Y2E4
GSSSGTITDEDELTG

ANKS6

766

Q68DC2
SISEEADSEPGRSGG

BRWD1

1786

Q9NSI6
SGVLASGDSTSGDPT

ATF7IP

146

Q6VMQ6
SGDATSGDAPSGDVS

ATF7IP

171

Q6VMQ6
SGDVSPGDATSGDAT

ATF7IP

181

Q6VMQ6
SSIEGGGPDATSATA

FAM43A

391

Q8N2R8
SSSGSETLSEEGEPG

MAST4

41

O15021
SDGSSSRGPEEEETG

KIRREL2

556

Q6UWL6
DTTVSGDTETGQSPG

EMILIN2

236

Q9BXX0
PADVEDTTGSGATDS

EEF1B2

81

P24534
GRDTSSTEVGSGPSD

C4orf54

461

D6RIA3
ARSSGSEGTPADTGD

PWWP2B

431

Q6NUJ5
TGLAASSEPEDGSEG

KIFC2

56

Q96AC6
ESESESESEAGPGTQ

LRRC43

6

Q8N309
GEGPSSTTESSERSE

PLEKHM2

376

Q8IWE5
DTSPDTNGGGSTSDT

IRF3

121

Q14653
TSVASPSSGGEDEDL

MEIS3P1

141

A6NDR6
TPGGRSDGDTDSVST

MINK1

851

Q8N4C8
SGSTDGLVDSAGTGD

SIDT2

366

Q8NBJ9
PGAEATSSTGEESGS

RRP1B

446

Q14684
ISTSSGSDDDSVGGE

PRUNE2

1681

Q8WUY3
DGEDTGLESVSSSGT

RAP1GAP

586

P47736
SAEEESSGGGSVTLD

SOWAHC

251

Q53LP3
GGASSDLETSSDPEG

PPP1R15B

431

Q5SWA1
EDNGSIGEETDSSPG

STIM1

656

Q13586
SEEAGGGSTFEGLST

CNOT11

76

Q9UKZ1
ATTSSGDTESEEGEG

SLC45A4

476

Q5BKX6
EEEGEDSGTSAASSP

PLEKHG5

721

O94827
EDSSPRGTLASSGDG

PLK3

406

Q9H4B4
DSSGGDSCASEEEPT

TBC1D17

66

Q9HA65
SEEDTGSEPSGSLSA

TTBK1

1061

Q5TCY1
SETLSGTGSEEDTPA

TTBK1

1121

Q5TCY1
DDGAFSTPTGGSDTL

SPEG

151

Q15772
GSSSEEAVGGDSTPS

SNX30

26

Q5VWJ9
SDSERSASSVEGPGG

SCARF2

611

Q96GP6
DTGPGESETCDSVSG

SUSD4

421

Q5VX71
NASAEGPEGEGTEST

TPT1

51

P13693
TSDETRGAEGTESSP

TACC2

1846

O95359
DTTTSGASDEEDGQP

SERINC3

376

Q13530
PESGTSGQSSDTESG

ZBTB20

216

Q9HC78
TLSGGSGGSESQEEE

ZNF853

41

P0CG23
DGGGIAEEPSTSSAS

UBXN7

51

O94888
PASDDEGSTAATDGS

UBR4

2866

Q5T4S7
SESSDTEDSAGGGPE

WNK4

1051

Q96J92
SGSGTSPESGDEEVS

TRIR

31

Q9BQ61
SPESGDEEVSGAGSS

TRIR

36

Q9BQ61
GLGAASTVDPSESTG

FAM53A

96

Q6NSI3
AETGSGTASDSGESV

NACA2

21

Q9H009
GTASDSGESVPGIEE

NACA2

26

Q9H009