Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	DNHD1 ABCF3 DYNC2H1 DHX37 TWNK TOR4A BTAF1 IDE MORC4 ABCA7 IQCA1L IQCA1 DQX1 RALBP1 DNA2 DYNC1H1 SLC27A3	3.49e-06	614	149	17	GO:0140657
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCF3 DYNC2H1 DHX37 TWNK TOR4A BTAF1 IDE MORC4 ABCA7 IQCA1L IQCA1 DQX1 DNA2 DYNC1H1	5.77e-06	441	149	14	GO:0016887
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNHD1 DYNC2H1 HOOK1 DYNC1H1	5.30e-05	28	149	4	GO:0051959
GeneOntologyMolecularFunction	peptide lactyltransferase (CoA-dependent) activity	CREBBP EP300	5.53e-05	2	149	2	GO:0120300
GeneOntologyMolecularFunction	histone H3K27 acetyltransferase activity	CREBBP EP300	5.53e-05	2	149	2	GO:0044017
GeneOntologyMolecularFunction	histone H3K18 acetyltransferase activity	CREBBP EP300	1.65e-04	3	149	2	GO:0043993
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ABCF3 DYNC2H1 DHX37 LRRK2 TWNK TOR4A BTAF1 IDE MORC4 ABCA7 IQCA1L IQCA1 DQX1 SEPTIN1 DNA2 DYNC1H1	2.27e-04	775	149	16	GO:0017111
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNHD1 DYNC2H1 DYNC1H1	3.06e-04	18	149	3	GO:0008569
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	CDK18 STK36 PDK1 LRRK2 SRPK1 SBK1 TGFBR1 UHMK1 AKT1 AKT2 STKLD1	5.32e-04	446	149	11	GO:0004674
GeneOntologyMolecularFunction	pyrophosphatase activity	ABCF3 DYNC2H1 DHX37 LRRK2 TWNK TOR4A BTAF1 IDE MORC4 ABCA7 IQCA1L IQCA1 DQX1 SEPTIN1 DNA2 DYNC1H1	5.43e-04	839	149	16	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ABCF3 DYNC2H1 DHX37 LRRK2 TWNK TOR4A BTAF1 IDE MORC4 ABCA7 IQCA1L IQCA1 DQX1 SEPTIN1 DNA2 DYNC1H1	5.50e-04	840	149	16	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ABCF3 DYNC2H1 DHX37 LRRK2 TWNK TOR4A BTAF1 IDE MORC4 ABCA7 IQCA1L IQCA1 DQX1 SEPTIN1 DNA2 DYNC1H1	5.50e-04	840	149	16	GO:0016818
GeneOntologyMolecularFunction	protein serine/threonine kinase binding	AP1B1 CLTC AKT1	7.35e-04	24	149	3	GO:0120283
GeneOntologyMolecularFunction	clathrin binding	LRRK2 AP1B1 AP2B1 CLTC	1.26e-03	63	149	4	GO:0030276
HumanPheno	Broad eyebrow	CREBBP POLR3A HERC1 EP300 SON	1.19e-05	29	55	5	HP:0011229
HumanPheno	Absent earlobe	CREBBP POLR3A DNA2 EP300	5.19e-05	20	55	4	HP:0000387
HumanPheno	Reduced social responsiveness	VPS13C LRRK2 CARS1 TWNK CREBBP SYNGAP1 CLTC HERC1 EP300	7.04e-05	170	55	9	HP:0012760
HumanPheno	Gait disturbance	CEP104 EMC1 COPB1 SZT2 DYNC2H1 MYOD1 VPS13C LRRK2 INTS1 CARS1 WDR81 TWNK NSUN2 INTS8 CREBBP POLR3A TCEAL1 SYNGAP1 CYP2R1 SACS FDXR CLTC AKT1 HERC1 DNA2 SLC9A6 EP300 DYNC1H1	9.83e-05	1356	55	28	HP:0001288
HumanPheno	Plantar crease between first and second toes	CREBBP EP300	1.14e-04	2	55	2	HP:0008107
HumanPheno	Aortic isthmus hypoplasia	CREBBP EP300	1.14e-04	2	55	2	HP:0034227
HumanPheno	High axial triradius	CREBBP EP300	1.14e-04	2	55	2	HP:0001042
Domain	ARM-type_fold	DOCK1 TNPO1 DOCK2 CEP104 STK36 COPB1 HGH1 LRRK2 INTS1 PSMD2 BTAF1 HEATR1 AP1B1 AP2B1 CLTC WDFY3 STKLD1 UNC79 TANGO6	3.63e-11	339	151	19	IPR016024
Domain	ARM-like	TNPO1 DOCK2 CEP104 STK36 COPB1 HGH1 LRRK2 PSMD2 BTAF1 HEATR1 AP1B1 AP2B1 WDFY3 STKLD1 TANGO6	5.32e-09	270	151	15	IPR011989
Domain	-	TNPO1 CEP104 STK36 COPB1 HGH1 LRRK2 PSMD2 BTAF1 HEATR1 AP1B1 AP2B1 WDFY3 TANGO6	3.14e-08	222	151	13	1.25.10.10
Domain	HEAT	TNPO1 CEP104 STK36 BTAF1 HEATR1	4.18e-05	48	151	5	PF02985
Domain	Nuc_rcpt_coact_CREBbp	CREBBP EP300	6.49e-05	2	151	2	IPR014744
Domain	ZnF_TAZ	CREBBP EP300	6.49e-05	2	151	2	SM00551
Domain	-	CREBBP EP300	6.49e-05	2	151	2	1.20.1020.10
Domain	RING_CBP-p300	CREBBP EP300	6.49e-05	2	151	2	IPR010303
Domain	-	CREBBP EP300	6.49e-05	2	151	2	1.10.1630.10
Domain	Creb_binding	CREBBP EP300	6.49e-05	2	151	2	PF09030
Domain	zf-TAZ	CREBBP EP300	6.49e-05	2	151	2	PF02135
Domain	ZF_TAZ	CREBBP EP300	6.49e-05	2	151	2	PS50134
Domain	Clathrin_b-adaptin_app_Ig-like	AP1B1 AP2B1	6.49e-05	2	151	2	IPR013037
Domain	KAT11	CREBBP EP300	6.49e-05	2	151	2	SM01250
Domain	Znf_TAZ	CREBBP EP300	6.49e-05	2	151	2	IPR000197
Domain	KIX	CREBBP EP300	6.49e-05	2	151	2	PF02172
Domain	HAT_KAT11	CREBBP EP300	6.49e-05	2	151	2	PF08214
Domain	KIX	CREBBP EP300	6.49e-05	2	151	2	PS50952
Domain	CBP_P300_HAT	CREBBP EP300	6.49e-05	2	151	2	IPR031162
Domain	DUF902	CREBBP EP300	6.49e-05	2	151	2	PF06001
Domain	-	AP1B1 AP2B1	6.49e-05	2	151	2	2.60.40.1150
Domain	-	CREBBP EP300	6.49e-05	2	151	2	1.10.246.20
Domain	Histone_AcTrfase_Rtt109/CBP	CREBBP EP300	6.49e-05	2	151	2	IPR013178
Domain	KIX_dom	CREBBP EP300	6.49e-05	2	151	2	IPR003101
Domain	CBP_P300_HAT	CREBBP EP300	6.49e-05	2	151	2	PS51727
Domain	HEAT	TNPO1 CEP104 STK36 BTAF1 HEATR1	1.05e-04	58	151	5	IPR000357
Domain	Dynein_HC_stalk	DNHD1 DYNC2H1 DYNC1H1	1.77e-04	14	151	3	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DYNC2H1 DYNC1H1	1.77e-04	14	151	3	IPR013602
Domain	DHC_N2	DNHD1 DYNC2H1 DYNC1H1	1.77e-04	14	151	3	PF08393
Domain	MT	DNHD1 DYNC2H1 DYNC1H1	1.77e-04	14	151	3	PF12777
Domain	AP_complex_bsu_1_2_4	AP1B1 AP2B1	1.94e-04	3	151	2	IPR016342
Domain	B2-adapt-app_C	AP1B1 AP2B1	1.94e-04	3	151	2	PF09066
Domain	DHC_fam	DNHD1 DYNC2H1 DYNC1H1	2.19e-04	15	151	3	IPR026983
Domain	Clathrin/coatomer_adapt-like_N	COPB1 AP1B1 AP2B1	2.19e-04	15	151	3	IPR002553
Domain	Dynein_heavy	DNHD1 DYNC2H1 DYNC1H1	2.19e-04	15	151	3	PF03028
Domain	Adaptin_N	COPB1 AP1B1 AP2B1	2.19e-04	15	151	3	PF01602
Domain	Dynein_heavy_dom	DNHD1 DYNC2H1 DYNC1H1	2.19e-04	15	151	3	IPR004273
Domain	HEAT_REPEAT	TNPO1 CEP104 BTAF1 HEATR1 TANGO6	2.56e-04	70	151	5	PS50077
Domain	B2-adapt-app_C	AP1B1 AP2B1	3.85e-04	4	151	2	SM01020
Domain	B-adaptin_app_sub_C	AP1B1 AP2B1	3.85e-04	4	151	2	IPR015151
Domain	-	PDK1 MORC4 SACS	5.34e-04	20	151	3	3.30.565.10
Domain	HATPase_C	PDK1 MORC4 SACS	6.19e-04	21	151	3	IPR003594
Domain	AP_beta	AP1B1 AP2B1	6.39e-04	5	151	2	IPR026739
Domain	DOCK_N	DOCK1 DOCK2	6.39e-04	5	151	2	PF16172
Domain	DOCK_N	DOCK1 DOCK2	6.39e-04	5	151	2	IPR032376
Domain	Nuc_rcpt_coact	CREBBP EP300	9.53e-04	6	151	2	IPR009110
Domain	Beta2_adaptin/TBP_C_dom	AP1B1 AP2B1	9.53e-04	6	151	2	IPR012295
Domain	-	AP1B1 AP2B1	9.53e-04	6	151	2	3.30.310.10
Domain	-	DNHD1 ABCF3 GTPBP6 DYNC2H1 DHX37 LRRK2 TWNK TOR4A BTAF1 ABCA7 IQCA1 DQX1 SEPTIN1 DNA2 DYNC1H1	1.07e-03	746	151	15	3.40.50.300
Domain	Pkinase	CDK18 STK36 LRRK2 SRPK1 SBK1 TGFBR1 UHMK1 AKT1 AKT2 STKLD1	1.09e-03	381	151	10	PF00069
Domain	Munc13_1	UNC13D CADPS2	1.33e-03	7	151	2	IPR014770
Domain	MHD1	UNC13D CADPS2	1.33e-03	7	151	2	PS51258
Domain	DUF1041	UNC13D CADPS2	1.33e-03	7	151	2	PF06292
Domain	CAPS_dom	UNC13D CADPS2	1.33e-03	7	151	2	IPR010439
Domain	P-loop_NTPase	DNHD1 ABCF3 GTPBP6 DYNC2H1 DHX37 LRRK2 TWNK TOR4A BTAF1 ABCA7 MYO15B IQCA1 DQX1 SEPTIN1 DNA2 DYNC1H1	1.41e-03	848	151	16	IPR027417
Domain	DHC_N1	DYNC2H1 DYNC1H1	1.76e-03	8	151	2	PF08385
Domain	Coatomer/calthrin_app_sub_C	AP1B1 AP2B1	1.76e-03	8	151	2	IPR009028
Domain	Dynein_heavy_dom-1	DYNC2H1 DYNC1H1	1.76e-03	8	151	2	IPR013594
Domain	Alpha_adaptinC2	AP1B1 AP2B1	2.25e-03	9	151	2	PF02883
Domain	BEACH	WDR81 WDFY3	2.25e-03	9	151	2	PS50197
Domain	Beach	WDR81 WDFY3	2.25e-03	9	151	2	PF02138
Domain	-	WDR81 WDFY3	2.25e-03	9	151	2	1.10.1540.10
Domain	Beach	WDR81 WDFY3	2.25e-03	9	151	2	SM01026
Domain	Clathrin_a/b/g-adaptin_app_Ig	AP1B1 AP2B1	2.25e-03	9	151	2	IPR008152
Domain	BEACH_dom	WDR81 WDFY3	2.25e-03	9	151	2	IPR000409
Domain	Alpha_adaptinC2	AP1B1 AP2B1	2.25e-03	9	151	2	SM00809
Domain	Ser/Thr_kinase_AS	CDK18 STK36 LRRK2 SRPK1 SBK1 TGFBR1 UHMK1 AKT1 AKT2	2.52e-03	357	151	9	IPR008271
Domain	S_TKc	CDK18 STK36 LRRK2 SRPK1 SBK1 TGFBR1 UHMK1 AKT1 AKT2	2.62e-03	359	151	9	SM00220
Domain	PROTEIN_KINASE_ST	CDK18 STK36 LRRK2 SRPK1 SBK1 TGFBR1 UHMK1 AKT1 AKT2	2.77e-03	362	151	9	PS00108
Domain	Leu-rich_rpt_4	PODNL1 LRRK2	2.80e-03	10	151	2	IPR025875
Domain	LRR_5	LRRC8C TSHR	2.80e-03	10	151	2	PF13306
Domain	LRR_5	LRRC8C TSHR	2.80e-03	10	151	2	IPR026906
Domain	LRR_4	PODNL1 LRRK2	2.80e-03	10	151	2	PF12799
Domain	DHR-1_domain	DOCK1 DOCK2	3.40e-03	11	151	2	IPR027007
Domain	DHR_2	DOCK1 DOCK2	3.40e-03	11	151	2	PS51651
Domain	DHR_1	DOCK1 DOCK2	3.40e-03	11	151	2	PS51650
Domain	DHR-2	DOCK1 DOCK2	3.40e-03	11	151	2	PF06920
Domain	DOCK	DOCK1 DOCK2	3.40e-03	11	151	2	IPR026791
Domain	DOCK_C	DOCK1 DOCK2	3.40e-03	11	151	2	IPR010703
Domain	DOCK-C2	DOCK1 DOCK2	3.40e-03	11	151	2	PF14429
Domain	DHR-2	DOCK1 DOCK2	3.40e-03	11	151	2	IPR027357
Domain	Coatomer/clathrin_app_Ig-like	AP1B1 AP2B1	4.06e-03	12	151	2	IPR013041
Domain	PROTEIN_KINASE_ATP	CDK18 STK36 LRRK2 SRPK1 SBK1 TGFBR1 UHMK1 AKT1 AKT2 STKLD1	4.20e-03	459	151	10	PS00107
Domain	Kinase-like_dom	CDK18 STK36 LRRK2 WDR81 SRPK1 SBK1 TGFBR1 UHMK1 AKT1 AKT2 STKLD1	4.63e-03	542	151	11	IPR011009
Domain	Dynein_heavy_chain_D4_dom	DYNC2H1 DYNC1H1	5.54e-03	14	151	2	IPR024317
Domain	ATPase_dyneun-rel_AAA	DYNC2H1 DYNC1H1	5.54e-03	14	151	2	IPR011704
Domain	AAA_8	DYNC2H1 DYNC1H1	5.54e-03	14	151	2	PF12780
Domain	AAA_5	DYNC2H1 DYNC1H1	5.54e-03	14	151	2	PF07728
Domain	AAA	ABCF3 DYNC2H1 TOR4A ABCA7 DYNC1H1	6.33e-03	144	151	5	SM00382
Domain	AAA+_ATPase	ABCF3 DYNC2H1 TOR4A ABCA7 DYNC1H1	6.33e-03	144	151	5	IPR003593
Domain	Prot_kinase_dom	CDK18 STK36 LRRK2 SRPK1 SBK1 TGFBR1 UHMK1 AKT1 AKT2 STKLD1	6.49e-03	489	151	10	IPR000719
Domain	PROTEIN_KINASE_DOM	CDK18 STK36 LRRK2 SRPK1 SBK1 TGFBR1 UHMK1 AKT1 AKT2 STKLD1	6.86e-03	493	151	10	PS50011
Pathway	REACTOME_RUNX2_REGULATES_GENES_INVOLVED_IN_CELL_MIGRATION	ITGA5 AKT1 AKT2	1.95e-05	8	101	3	M27806
Pathway	REACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING	UHMK1 AKT1 AKT2	2.91e-05	9	101	3	MM15666
Pathway	WP_GROWTH_FACTORS_AND_HORMONES_IN_BETA_CELL_PROLIFERATION	TGFBR1 RASSF1 AKT1 AKT2	3.29e-05	26	101	4	M48092
Pathway	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	CREBBP AKT1 AKT2 EP300	2.25e-04	42	101	4	M17541
Pathway	BIOCARTA_TGFB_PATHWAY	CREBBP TGFBR1 EP300	2.26e-04	17	101	3	MM1509
Pathway	REACTOME_KEAP1_NFE2L2_PATHWAY	PSMD2 CREBBP GSTA3 AKT1 AKT2 EP300	2.75e-04	125	101	6	M45021
Pathway	BIOCARTA_TGFB_PATHWAY	CREBBP TGFBR1 EP300	3.18e-04	19	101	3	M18933
Pathway	REACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES	CREBBP GSTA3 EP300	3.18e-04	19	101	3	M46442
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION	AKT1 AKT2 EP300	4.98e-04	22	101	3	MM15656
Pathway	BIOCARTA_NTHI_PATHWAY	CREBBP TGFBR1 EP300	4.98e-04	22	101	3	MM1443
Pathway	REACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES	CREBBP EP300	5.01e-04	5	101	2	M48020
Pathway	REACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES	CREBBP EP300	5.01e-04	5	101	2	M48023
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	5.01e-04	5	101	2	MM1575
Pathway	KEGG_MEDICUS_VARIANT_LOSS_OF_NKX3_1_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	5.01e-04	5	101	2	M48999
Pathway	REACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION	CREBBP EP300	5.01e-04	5	101	2	M27228
Pathway	BIOCARTA_NTHI_PATHWAY	CREBBP TGFBR1 EP300	5.70e-04	23	101	3	M2821
Pathway	WP_TGFBETA_RECEPTOR_SIGNALING	CREBBP LEFTY2 TGFBR1 EP300	6.40e-04	55	101	4	M39351
Pathway	REACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING	UHMK1 AKT1 AKT2	6.48e-04	24	101	3	M27952
Pathway	BIOCARTA_HDAC_PATHWAY	MYOD1 NFATC1 AKT1	7.32e-04	25	101	3	M1547
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	7.48e-04	6	101	2	M22062
Pathway	KEGG_MEDICUS_REFERENCE_MAGI_PTEN_SIGNALING_PATHWAY	AKT1 AKT2	7.48e-04	6	101	2	M47523
Pathway	WP_HEPATITIS_B_INFECTION	CREBBP TGFBR1 NFATC1 AKT1 AKT2 EP300	7.51e-04	151	101	6	M39801
Pathway	BIOCARTA_HDAC_PATHWAY	MYOD1 NFATC1 AKT1	8.23e-04	26	101	3	MM1371
Pathway	PID_HDAC_CLASSIII_PATHWAY	MYOD1 CREBBP EP300	8.23e-04	26	101	3	M32
Pathway	PID_P53_REGULATION_PATHWAY	CREBBP RASSF1 AKT1 EP300	8.35e-04	59	101	4	M261
Pathway	WP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS	CREBBP LEFTY2 TGFBR1 EP300	8.35e-04	59	101	4	M39886
Pathway	REACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS	DOCK2 AP1B1 AP2B1	1.03e-03	28	101	3	M11362
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PI3K_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.04e-03	7	101	2	M47407
Pathway	KEGG_MEDICUS_REFERENCE_ACH_CHRN_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.04e-03	7	101	2	M47790
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP EP300	1.04e-03	7	101	2	MM1573
Pathway	WP_LIPID_METABOLISM_PATHWAY	ACACA AKT1 AKT2	1.14e-03	29	101	3	M39762
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION	AKT1 AKT2 EP300	1.14e-03	29	101	3	MM15340
Pathway	PID_RETINOIC_ACID_PATHWAY	CREBBP AKT1 EP300	1.26e-03	30	101	3	M207
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION	AKT1 AKT2 EP300	1.26e-03	30	101	3	M27637
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION	CREBBP AKT1 AKT2 EP300	1.27e-03	66	101	4	M27938
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP EP300	1.38e-03	8	101	2	M22058
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.38e-03	8	101	2	M47399
Pathway	REACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES	CREBBP EP300	1.38e-03	8	101	2	M48022
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.38e-03	8	101	2	M47394
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.38e-03	8	101	2	M47395
Pathway	REACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION	CREBBP EP300	1.38e-03	8	101	2	M48024
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.38e-03	8	101	2	M47404
Pathway	KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.38e-03	8	101	2	M47405
Pathway	KEGG_MEDICUS_REFERENCE_P4_PR_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.38e-03	8	101	2	M47803
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_RET_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.38e-03	8	101	2	M47715
Pathway	KEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.38e-03	8	101	2	M47482
Pathway	KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.38e-03	8	101	2	M47498
Pathway	REACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES	CREBBP EP300	1.38e-03	8	101	2	M46443
Pathway	WP_UROTENSINIIMEDIATED_SIGNALING	CREBBP UTS2 AKT1 EP300	1.50e-03	69	101	4	M48052
Pathway	WP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR	CREBBP NFATC1 EP300	1.52e-03	32	101	3	M39521
Pathway	KEGG_RENAL_CELL_CARCINOMA	CREBBP AKT1 AKT2 EP300	1.58e-03	70	101	4	M13266
Pathway	KEGG_PANCREATIC_CANCER	TGFBR1 RALBP1 AKT1 AKT2	1.58e-03	70	101	4	M9726
Pathway	REACTOME_VIRAL_INFECTION_PATHWAYS	DOCK2 UBE2L6 MED8 PSMD2 SRPK1 CREBBP NUP205 AP1B1 AP2B1 VPS33B CLTC AKT1 AKT2 EP300 DYNC1H1	1.59e-03	888	101	15	M48034
Pathway	REACTOME_SIGNALING_BY_WNT	PSMD2 AP2B1 NFATC1 CLTC AKT1 AKT2 EP300	1.64e-03	239	101	7	MM14756
Pathway	WP_NONSMALL_CELL_LUNG_CANCER	PDK1 RASSF1 AKT1 AKT2	1.76e-03	72	101	4	M39738
Pathway	WP_FRAGILE_X_SYNDROME	PDK1 SYNGAP1 AP2B1 CLTC AKT1	1.76e-03	121	101	5	M39804
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.77e-03	9	101	2	M47397
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.77e-03	9	101	2	M47392
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.77e-03	9	101	2	M47391
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.77e-03	9	101	2	M47402
Pathway	KEGG_MEDICUS_REFERENCE_MEMBRANE_INITIATED_PROGESTERONE_SIGNALING_PATHWAY	AKT1 AKT2	1.77e-03	9	101	2	M47802
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_MET_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.77e-03	9	101	2	M47490
Pathway	KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.77e-03	9	101	2	M47481
Pathway	KEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY	CREBBP EP300	1.77e-03	9	101	2	M47451
Pathway	KEGG_MEDICUS_REFERENCE_ICOSLG_ICOS_PI3K_SIGNALING_PATHWAY	AKT1 AKT2	1.77e-03	9	101	2	M47972
Pathway	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION	POLR3A GTF3C1 SNAPC2	1.82e-03	34	101	3	MM15435
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	STK36 CRYBG2 ACACA GTPBP6 SZT2 TMEM8B INTS1 APEH TWNK TOR4A BTAF1 SMG5 ITGA5 ABCA7 EHBP1L1 CELSR2 NFATC1 A4GALT AKT1 AKT2 WDFY3 HERC1 EP300 DYNC1H1	1.32e-10	1105	154	24	35748872
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TNPO1 ACACA COPB1 DHX37 INTS1 PSMD2 SRPK1 HEATR1 URB2 NSUN2 NUP205 GTF3C1 AP1B1 AP2B1 CLTC DYNC1H1 SON	5.83e-09	653	154	17	22586326
Pubmed	Functional interdependence at the chromatin level between the MKK6/p38 and IGF1/PI3K/AKT pathways during muscle differentiation.	MYOD1 AKT1 AKT2 EP300	2.55e-08	8	154	4	17964260
Pubmed	Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming.	PDK1 AKT1 AKT2	8.51e-08	3	154	3	27505672
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	TNPO1 EMC1 ACACA COPB1 SZT2 DYNC2H1 NCAPH2 HEATR1 IGBP1 TRAFD1 HOOK1 NFATC1 PANK4 DNA2 SON	9.25e-08	606	154	15	36538041
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	TNPO1 EMC1 COPB1 HGH1 DYNC2H1 PSMD2 BTAF1 HEATR1 URB2 NSUN2 INTS8 NUP205 TRAFD1 HOOK1 AP1B1 CLTC DYNC1H1 SLC27A3	2.18e-07	942	154	18	31073040
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	TNPO1 EMC1 ABCF3 ACACA COPB1 HGH1 PSMD2 SRPK1 BTAF1 IGBP1 UTS2 AP1B1 AP2B1 PANK4 EP300	2.41e-07	653	154	15	33742100
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	GTPBP6 COPB1 APEH PSMD2 NCAPH2 SMG5 NSUN2 INTS8 CREBBP SYNGAP1 AP2B1 SACS ARHGEF10 RALBP1 CLTC CERCAM WDFY3 UROD CADPS2 EP300 DYNC1H1	2.67e-07	1285	154	21	35914814
Pubmed	Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2C.	MYOD1 CREBBP EP300	3.39e-07	4	154	3	9001254
Pubmed	Differential roles of p300 and PCAF acetyltransferases in muscle differentiation.	MYOD1 CREBBP EP300	3.39e-07	4	154	3	9659901
Pubmed	Interaction between acetylated MyoD and the bromodomain of CBP and/or p300.	MYOD1 CREBBP EP300	3.39e-07	4	154	3	11463815
Pubmed	CREB-binding protein/p300 activates MyoD by acetylation.	MYOD1 CREBBP EP300	3.39e-07	4	154	3	10944526
Pubmed	Hepatitis C virus core protein regulates p300/CBP co-activation function. Possible role in the regulation of NF-AT1 transcriptional activity.	CREBBP NFATC1 EP300	3.39e-07	4	154	3	15380363
Pubmed	Interaction of human biliverdin reductase with Akt/protein kinase B and phosphatidylinositol-dependent kinase 1 regulates glycogen synthase kinase 3 activity: a novel mechanism of Akt activation.	PDK1 AKT1 AKT2	3.39e-07	4	154	3	27166089
Pubmed	SRPK1 and Akt Protein Kinases Phosphorylate the RS Domain of Lamin B Receptor with Distinct Specificity: A Combined Biochemical and In Silico Approach.	SRPK1 AKT1 AKT2	3.39e-07	4	154	3	27105349
Pubmed	Activation of the beta myosin heavy chain promoter by MEF-2D, MyoD, p300, and the calcineurin/NFATc1 pathway.	MYOD1 NFATC1 EP300	3.39e-07	4	154	3	17111365
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	COPB1 INTS1 PSMD2 BTAF1 PCGF6 GTF3C1 NFATC1 CLTC SPINDOC DYNC1H1	4.14e-07	272	154	10	31010829
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	ABCF3 ACACA COPB1 DHX37 PSMD2 SRPK1 TOR4A HEATR1 URB2 NSUN2 CREBBP POLR3A NUP205 PCGF6 GTF3C1 AP2B1 VPS33B CLTC WDFY3 DYNC1H1 SON	6.17e-07	1353	154	21	29467282
Pubmed	Human p300 protein is a coactivator for the transcription factor MyoD.	MYOD1 CREBBP EP300	8.46e-07	5	154	3	8621548
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	DYNC2H1 MED8 IDE URB2 ITGA5 MORC4 CREBBP EXD3 EHBP1L1 AP1B1 UBP1 CDK5RAP2 WDFY3 EP300	1.06e-06	638	154	14	31182584
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	UBR2 ABCF3 TWNK BTAF1 SMG5 HEATR1 CREBBP NUP205 PCGF6 GTF3C1 NFATC1 UBP1 PANK4 ZBTB40 EP300 DYNC1H1	1.45e-06	857	154	16	25609649
Pubmed	UHRF1 inhibits MDR1 gene transcription and sensitizes breast cancer cells to anticancer drugs.	MYOD1 CREBBP EP300	1.69e-06	6	154	3	20037778
Pubmed	Regulation of T cell activation by HIV-1 accessory proteins: Vpr acts via distinct mechanisms to cooperate with Nef in NFAT-directed gene expression and to promote transactivation by CREB.	CREBBP NFATC1 EP300	1.69e-06	6	154	3	12788643
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DOCK1 TNPO1 DOCK2 ABCF3 COPB1 INTS1 PSMD2 BTAF1 INTS8 MYO15B AP1B1 VPS33B DYNC1H1	2.15e-06	582	154	13	20467437
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TNPO1 CDK18 EMC1 DYNC2H1 PDK1 APEH TWNK SRPK1 HEATR1 TRAPPC8 PCGF6 SACS ARHGEF10 CLMN CLTC PANK4 ASCC2 CDK5RAP2 AKT2 MLLT11 DNA2	2.75e-06	1487	154	21	33957083
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DOCK1 UBR2 INTU SGSM1 ACACA GTPBP6 TMEM8B VPS13C TMPRSS6 BTAF1 IDE CCDC57 INTS8 CREBBP SBK1 EXD3 GTF3C1 NFATC1 CLMN PANK4 EP300	2.81e-06	1489	154	21	28611215
Pubmed	Ginsenoside Rh1 eliminates the cytoprotective phenotype of human immunodeficiency virus type 1-transduced human macrophages by inhibiting the phosphorylation of pyruvate dehydrogenase lipoamide kinase isozyme 1.	PDK1 AKT1 AKT2	2.94e-06	7	154	3	23811558
Pubmed	Inhibition of HIV-1 Tat-mediated transcription by a coumarin derivative, BPRHIV001, through the Akt pathway.	AKT1 AKT2 EP300	2.94e-06	7	154	3	21697490
Pubmed	Differential role of p300 and CBP acetyltransferase during myogenesis: p300 acts upstream of MyoD and Myf5.	MYOD1 CREBBP EP300	2.94e-06	7	154	3	14517256
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	EMC1 ACACA COPB1 DHX37 INTS1 PSMD2 BTAF1 MORC4 NSUN2 POLR3A NUP205 IGBP1 TRAFD1 GTF3C1 CLTC PANK4 QPCT DNA2 DYNC1H1	3.25e-06	1257	154	19	37317656
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	EMC1 ACACA COPB1 DHX37 HEATR1 URB2 POLR3A NUP205 GTF3C1 VPS33B FDXR CLTC DYNC1H1 SON	3.32e-06	704	154	14	29955894
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	EMC1 VPS13C WDR81 BTAF1 URB2 TRAPPC8 INTS8 EHBP1L1 AP1B1 ARHGEF10 FDXR ITPRIP HERC1 UROD	4.22e-06	719	154	14	35337019
Pubmed	Defining the membrane proteome of NK cells.	DOCK2 LRRC8C ABCF3 COPB1 INTS1 PSMD2 NCAPH2 HEATR1 POLR3A NUP205 EHBP1L1 GTF3C1 AP2B1 CLTC ITPRIP DYNC1H1 SLC27A3 CYB5R1	4.62e-06	1168	154	18	19946888
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	TNPO1 DNHD1 EMC1 ACACA COPB1 DYNC2H1 DHX37 VPS13C CARS1 PSMD2 HEATR1 IDE URB2 NSUN2 POLR3A NUP205 GTF3C1 VPS33B CLTC DYNC1H1	5.32e-06	1425	154	20	30948266
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TNPO1 ABCF3 UNC13D HEATR1 PRAMEF18 TGFBR1 VPS33B CLMN UBP1 RASSF1 CLTC ZBTB40 CDK5RAP2 ITPRIP HERC1 DNA2 BICC1	6.89e-06	1084	154	17	11544199
Pubmed	Genetic link between renal birth defects and congenital heart disease.	DYNC2H1 AP1B1 AP2B1 BICC1	6.97e-06	28	154	4	27002738
Pubmed	Clint: a novel clathrin-binding ENTH-domain protein at the Golgi.	AP1B1 AP2B1 CLTC	7.01e-06	9	154	3	12429846
Pubmed	DNA-PKcs, but not TLR9, is required for activation of Akt by CpG-DNA.	PDK1 AKT1 AKT2	7.01e-06	9	154	3	15678105
Pubmed	The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy.	PDK1 AKT1 EP300	7.01e-06	9	154	3	21775285
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	REC8 TNPO1 ACACA SZT2 INTS1 PSMD2 UNC13D NCAPH2 HEATR1 NSUN2 TMEM121 NUP205 TGFBR1 IGBP1 UBP1 CLTC ZBTB40 SNAPC2 EP300	7.05e-06	1327	154	19	32694731
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	TNPO1 ABCF3 ACACA COPB1 HGH1 CARS1 APEH PSMD2 UNC13D IDE NSUN2 NUP205 EHBP1L1 AP1B1 AP2B1 ARHGEF10 PANK4 HERC1 UROD DYNC1H1	7.23e-06	1455	154	20	22863883
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	TNPO1 COPB1 PDK1 PSMD2 HOOK1 AP1B1 AP2B1 VPS33B CLTC PANK4 ASCC2 DYNC1H1	8.15e-06	560	154	12	35241646
Pubmed	Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation.	DOCK1 ITGA5 AKT1 AKT2	9.26e-06	30	154	4	24472646
Pubmed	Estrogen receptor (ER) beta or p53 attenuates ERalpha-mediated transcriptional activation on the BRCA2 promoter.	MYOD1 CREBBP EP300	9.99e-06	10	154	3	18765668
Pubmed	The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters.	TNPO1 ACACA COPB1 PSMD2	1.37e-05	33	154	4	26296893
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	INTS1 SRPK1 CREBBP TGFBR1 PCGF6 GTF3C1 AP1B1 AP2B1 RALBP1 RASSF1 FDXR CDK5RAP2 AKT1 AKT2 EP300	1.38e-05	910	154	15	36736316
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ACACA HGH1 DHX37 MRM1 CCDC57 SYNGAP1 TRAFD1 GTF3C1 SEPTIN1 ASCC2 HERC1	1.46e-05	497	154	11	36774506
Pubmed	Loss of p300 accelerates MDS-associated leukemogenesis.	CREBBP EP300	1.95e-05	2	154	2	27881875
Pubmed	Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells.	AKT1 AKT2	1.95e-05	2	154	2	27878243
Pubmed	BAY 1125976, a selective allosteric AKT1/2 inhibitor, exhibits high efficacy on AKT signaling-dependent tumor growth in mouse models.	AKT1 AKT2	1.95e-05	2	154	2	27699769
Pubmed	Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.	CREBBP EP300	1.95e-05	2	154	2	34845315
Pubmed	LRRK2 directly phosphorylates Akt1 as a possible physiological substrate: impairment of the kinase activity by Parkinson's disease-associated mutations.	LRRK2 AKT1	1.95e-05	2	154	2	21658387
Pubmed	A giant protein that stimulates guanine nucleotide exchange on ARF1 and Rab proteins forms a cytosolic ternary complex with clathrin and Hsp70.	CLTC HERC1	1.95e-05	2	154	2	9233772
Pubmed	p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.	CREBBP EP300	1.95e-05	2	154	2	19729597
Pubmed	Isoform-Specific Role of Akt in Oral Squamous Cell Carcinoma.	AKT1 AKT2	1.95e-05	2	154	2	31252679
Pubmed	Akt1 is critical for acute inflammation and histamine-mediated vascular leakage.	AKT1 AKT2	1.95e-05	2	154	2	19622728
Pubmed	Expression of AKT1 along with AKT2 in granulosa-lutein cells of hyperandrogenic PCOS patients.	AKT1 AKT2	1.95e-05	2	154	2	28271235
Pubmed	Role of Akt in cardiac growth and metabolism.	AKT1 AKT2	1.95e-05	2	154	2	17019809
Pubmed	Increased Phospho-AKT in Blood Cells from LRRK2 G2019S Mutation Carriers.	LRRK2 AKT1	1.95e-05	2	154	2	35929078
Pubmed	CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.	CREBBP EP300	1.95e-05	2	154	2	39287984
Pubmed	Knockout of Akt1/2 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo.	AKT1 AKT2	1.95e-05	2	154	2	33377281
Pubmed	Akt2 mRNA is highly expressed in embryonic brown fat and the AKT2 kinase is activated by insulin.	AKT1 AKT2	1.95e-05	2	154	2	9620559
Pubmed	Akt1 and Akt2 differently regulate muscle creatine kinase and myogenin gene transcription in insulin-induced differentiation of C2C12 myoblasts.	AKT1 AKT2	1.95e-05	2	154	2	11861503
Pubmed	Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.	CREBBP EP300	1.95e-05	2	154	2	20717166
Pubmed	Akt regulates basic helix-loop-helix transcription factor-coactivator complex formation and activity during neuronal differentiation.	AKT1 AKT2	1.95e-05	2	154	2	12808085
Pubmed	Impaired expression and insulin-stimulated phosphorylation of Akt-2 in muscle of obese patients with atypical diabetes.	AKT1 AKT2	1.95e-05	2	154	2	15010337
Pubmed	RLIP76 regulates PI3K/Akt signaling and chemo-radiotherapy resistance in pancreatic cancer.	RALBP1 AKT1	1.95e-05	2	154	2	22509328
Pubmed	Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy.	AKT1 AKT2	1.95e-05	2	154	2	36229454
Pubmed	Akt2 regulates cardiac metabolism and cardiomyocyte survival.	AKT1 AKT2	1.95e-05	2	154	2	16950770
Pubmed	The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.	CREBBP EP300	1.95e-05	2	154	2	25893291
Pubmed	Akt isoforms differentially regulate neutrophil functions.	AKT1 AKT2	1.95e-05	2	154	2	20332370
Pubmed	Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.	CREBBP EP300	1.95e-05	2	154	2	11559821
Pubmed	Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma.	AKT1 AKT2	1.95e-05	2	154	2	3037531
Pubmed	High-intensity muscle contraction-mediated increases in Akt1 and Akt2 phosphorylation do not contribute to mTORC1 activation and muscle protein synthesis.	AKT1 AKT2	1.95e-05	2	154	2	32078465
Pubmed	CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.	CREBBP EP300	1.95e-05	2	154	2	32576962
Pubmed	Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.	CREBBP EP300	1.95e-05	2	154	2	19822209
Pubmed	Defining Akt actions in muscle differentiation.	AKT1 AKT2	1.95e-05	2	154	2	23076793
Pubmed	Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer.	AKT1 AKT2	1.95e-05	2	154	2	19110052
Pubmed	Loss of Akt1 or Akt2 delays mammary tumor onset and suppresses tumor growth rate in MTB-IGFIR transgenic mice.	AKT1 AKT2	1.95e-05	2	154	2	23919516
Pubmed	Cutaneous human papillomaviruses down-regulate AKT1, whereas AKT2 up-regulation and activation associates with tumors.	AKT1 AKT2	1.95e-05	2	154	2	17804734
Pubmed	A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.	CREBBP EP300	1.95e-05	2	154	2	24522976
Pubmed	Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1.	DOCK1 DOCK2	1.95e-05	2	154	2	28467910
Pubmed	Lack of AKT in adipocytes causes severe lipodystrophy.	AKT1 AKT2	1.95e-05	2	154	2	27408773
Pubmed	Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation.	AKT1 AKT2	1.95e-05	2	154	2	17141631
Pubmed	CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.	CREBBP EP300	1.95e-05	2	154	2	21847097
Pubmed	PI3K/AKT Signaling in Breast Cancer Molecular Subtyping and Lymph Node Involvement.	AKT1 AKT2	1.95e-05	2	154	2	31781306
Pubmed	Role of Akt/protein kinase B in the activity of transcriptional coactivator p300.	AKT1 EP300	1.95e-05	2	154	2	15224190
Pubmed	Genetic analysis of the cytoplasmic dynein subunit families.	DYNC2H1 DYNC1H1	1.95e-05	2	154	2	16440056
Pubmed	Beta-HPV 5 and 8 E6 promote p300 degradation by blocking AKT/p300 association.	AKT1 EP300	1.95e-05	2	154	2	21901101
Pubmed	Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners.	REC8 NCAPH2	1.95e-05	2	154	2	12667442
Pubmed	p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.	CREBBP EP300	1.95e-05	2	154	2	34813504
Pubmed	Akt-1 and Akt-2 Differentially Regulate the Development of Experimental Autoimmune Encephalomyelitis by Controlling Proliferation of Thymus-Derived Regulatory T Cells.	AKT1 AKT2	1.95e-05	2	154	2	30692211
Pubmed	Distinct actions of akt1 on skeletal architecture and function.	AKT1 AKT2	1.95e-05	2	154	2	24663486
Pubmed	Akt1 and akt2 play distinct roles in the initiation and metastatic phases of mammary tumor progression.	AKT1 AKT2	1.95e-05	2	154	2	19491266
Pubmed	Rubinstein-Taybi Syndrome	CREBBP EP300	1.95e-05	2	154	2	20301699
Pubmed	Endothelin-1-dependent nuclear factor of activated T lymphocyte signaling associates with transcriptional coactivator p300 in the activation of the B cell leukemia-2 promoter in cardiac myocytes.	NFATC1 EP300	1.95e-05	2	154	2	15117818
Pubmed	Potential biomarker of metformin action.	CREBBP EP300	1.95e-05	2	154	2	24639469
Pubmed	The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.	CREBBP EP300	1.95e-05	2	154	2	37816914
Pubmed	Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation.	AKT1 AKT2	1.95e-05	2	154	2	17609365
Pubmed	Identification of functional domains in AKT responsible for distinct roles of AKT isoforms in pressure-stimulated cancer cell adhesion.	AKT1 AKT2	1.95e-05	2	154	2	17825284
Interaction	ITGB3 interactions	COPB1 PDK1 PSMD2 ITGA5 AP1B1 CLTC AKT1 DYNC1H1 SON	4.97e-06	170	149	9	int:ITGB3
Interaction	TOP3B interactions	STK36 CRYBG2 ACACA GTPBP6 SZT2 TMEM8B INTS1 APEH TWNK TOR4A BTAF1 SMG5 ITGA5 ABCA7 EHBP1L1 CELSR2 NFATC1 LRRC31 A4GALT AKT1 AKT2 WDFY3 HERC1 KLHL14 DNA2 EP300 DYNC1H1	9.41e-06	1470	149	27	int:TOP3B
Interaction	C1orf87 interactions	UBR2 LRRK2 CDK5RAP2 HERC1	1.56e-05	21	149	4	int:C1orf87
Interaction	EEF1AKMT3 interactions	ABCF3 VPS13C WDR81 IGBP1 EHBP1L1 GTF3C1 HOOK1 ARHGEF10 SELENOO ASCC2 AKT1 HERC1	1.74e-05	364	149	12	int:EEF1AKMT3
Interaction	RUNX1 interactions	UBE2L6 GTPBP6 MYOD1 APEH CREBBP NFATC1 UBP1 CLTC CERCAM UROD EP300	3.01e-05	324	149	11	int:RUNX1
Interaction	EP300 interactions	TNPO1 EMC1 ABCF3 ACACA COPB1 HGH1 MYOD1 PSMD2 SRPK1 BTAF1 CREBBP TGFBR1 IGBP1 UTS2 GTF3C1 AP1B1 AP2B1 NFATC1 CLTC PANK4 AKT1 HERC1 DNA2 EP300 SON	3.43e-05	1401	149	25	int:EP300
Interaction	SIRT7 interactions	TNPO1 ACACA COPB1 DHX37 INTS1 PSMD2 SRPK1 HEATR1 URB2 NSUN2 NUP205 GTF3C1 AP1B1 AP2B1 CLTC DYNC1H1 SON	3.71e-05	744	149	17	int:SIRT7
Interaction	BAG5 interactions	REC8 UBE2L6 COPB1 VPS13C LRRK2 PSMD2 NSUN2 CREBBP ARHGEF10 CLTC CERCAM	4.79e-05	341	149	11	int:BAG5
Interaction	FOXB1 interactions	COPB1 BTAF1 HEATR1 NUP205 GTF3C1 ZBTB40 DYNC1H1	6.59e-05	135	149	7	int:FOXB1
Interaction	CLEC16A interactions	TNPO1 EMC1 ACACA COPB1 SZT2 DYNC2H1 NCAPH2 HEATR1 IGBP1 TRAFD1 HOOK1 NFATC1 PANK4 DNA2 SON	6.78e-05	629	149	15	int:CLEC16A
Interaction	DUSP16 interactions	SZT2 DYNC2H1 VPS13C SMG5 HOOK1 ASCC2 CDK5RAP2 DNA2 DYNC1H1	6.92e-05	237	149	9	int:DUSP16
Cytoband	10q22-q23	BTAF1 POLR3A	1.13e-04	5	155	2	10q22-q23
Coexpression	COLDREN_GEFITINIB_RESISTANCE_UP	TWNK IDE PCGF6 SACS QPCT CDK5RAP2 ITPRIP MLLT11	4.26e-08	86	154	8	M18134
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	CEP104 VPS13C CREBBP NUP205 GTF3C1 CELSR2 ZBTB40 HERC1 EP300	1.25e-06	180	154	9	M8239
ToppCell	LPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	INTU PBX4 TOR4A SMG5 UNC5CL FDXR SELENOO	1.33e-06	157	155	7	bd45590da540a557dc8096980a45220fccb99505
ToppCell	LPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	INTU PBX4 TOR4A SMG5 UNC5CL FDXR SELENOO	1.33e-06	157	155	7	00c9a58b033b8b95b0d838f233dd077b62d8b02a
ToppCell	343B-Lymphocytic-ILC-ILC-1\|343B / Donor, Lineage, Cell class and subclass (all cells)	HEATR1 BCAS4 NSUN2 NUP205 CYP2R1 CDK5RAP2 CFAP46	4.39e-06	188	155	7	8f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCell	BAL-Control-Lymphocyte-B-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DHX37 LRRK2 PBX4 TWNK BCAS4 NFATC1 SACS	4.71e-06	190	155	7	da7341a8a423e5fe4d8e733d8e50c10a3318ac1c
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	TMPRSS6 RHBDL1 FAM135B BIK A4GALT QPCT UNC79	4.71e-06	190	155	7	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DHX37 LRRK2 PBX4 TWNK BCAS4 NFATC1 SACS	4.71e-06	190	155	7	42312f7d79fe889397d32910b625793e2535cc26
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DHX37 LRRK2 PBX4 TWNK BCAS4 NFATC1 SACS	4.71e-06	190	155	7	682418a7a2096743112eae3790d40e7e600612c0
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	TNPO1 HOOK1 UHMK1 CLTC WDFY3 DYNC1H1 SON	5.22e-06	193	155	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DYNC2H1 VPS13C TMPRSS6 CLTC HERC1 DYNC1H1 SON	5.58e-06	195	155	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DYNC2H1 VPS13C TMPRSS6 CLTC HERC1 DYNC1H1 SON	5.58e-06	195	155	7	7796ea9247f4c63762f0de8490fed08b9717fa23
Drug	Be-H	INTU TMEM121 QPCT HAS1 DYNC1H1	4.46e-07	24	150	5	CID000444973
Disease	microcephaly (implicated_via_orthology)	DHX37 CARS1 WDR81 CDK5RAP2	1.96e-05	32	148	4	DOID:10907 (implicated_via_orthology)
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	2.50e-05	2	148	2	180849
Disease	Rubinstein-Taybi syndrome due to CREBBP mutations	CREBBP EP300	2.50e-05	2	148	2	cv:C4551859
Disease	Menke-Hennekam syndrome	CREBBP EP300	2.50e-05	2	148	2	cv:C5681632
Disease	Rubinstein-Taybi syndrome (implicated_via_orthology)	CREBBP EP300	2.50e-05	2	148	2	DOID:1933 (implicated_via_orthology)
Disease	Rubinstein-Taybi syndrome	CREBBP EP300	2.50e-05	2	148	2	cv:C0035934
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	2.50e-05	2	148	2	C4551859
Disease	Rubinstein-Taybi syndrome (is_implicated_in)	CREBBP EP300	2.50e-05	2	148	2	DOID:1933 (is_implicated_in)
Disease	Rubinstein-Taybi Syndrome	CREBBP EP300	2.50e-05	2	148	2	C0035934
Disease	alcohol use disorder (implicated_via_orthology)	RHBDL1 CREBBP JMJD7 AKT1 AKT2 UNC79 EP300	6.02e-05	195	148	7	DOID:1574 (implicated_via_orthology)
Disease	autism spectrum disorder (implicated_via_orthology)	CREBBP SYNGAP1 ARHGEF10 WDFY3 CADPS2 NAA16	1.22e-04	152	148	6	DOID:0060041 (implicated_via_orthology)
Disease	obsolete_red blood cell distribution width	TNPO1 TMPRSS6 APEH PBX4 UNC13D NCAPH2 SMG5 ABCA7 EHBP1L1 HOOK1 AP2B1 VPS33B RP1L1 A4GALT ZBTB40 HERC1 STKLD1 EP300	1.48e-04	1347	148	18	EFO_0005192
Disease	hemojuvelin measurement	TMEM8B CELSR2	2.47e-04	5	148	2	EFO_0008148
Disease	erythrocyte measurement	TMPRSS6 NCAPH2 ABCA7 HOOK1 AP2B1 RP1L1 ZBTB40	3.30e-04	257	148	7	EFO_0005047
Disease	Inflammatory Myofibroblastic Tumor	CARS1 CLTC	3.70e-04	6	148	2	C0334121
Disease	mean corpuscular hemoglobin concentration	TNPO1 INTU TMPRSS6 PSMD2 SRPK1 SMG5 TSHR URB2 INTS8 ABCA7 EHBP1L1 HOOK1 RP1L1 A4GALT ASCC2	4.59e-04	1105	148	15	EFO_0004528
Disease	asphyxiating thoracic dystrophy (is_implicated_in)	INTU DYNC2H1	5.16e-04	7	148	2	DOID:0050592 (is_implicated_in)
Disease	cardiomyopathy (is_marker_for)	UTS2 EP300	5.16e-04	7	148	2	DOID:0050700 (is_marker_for)
Disease	HbA1c measurement	CEP104 CCDC184 TMPRSS6 SMG5 SBK1 HOOK1 CYP2R1 A4GALT ASCC2 QPCT STKLD1	6.25e-04	675	148	11	EFO_0004541
Disease	repulsive guidance molecule A measurement	TMEM8B CELSR2	8.79e-04	9	148	2	EFO_0008273
Disease	lactosyl-N-nervonoyl-sphingosine (d18:1/24:1) measurement	ABCA7 A4GALT	8.79e-04	9	148	2	EFO_0800517
Disease	Neoplasm of uncertain or unknown behavior of breast	AKT1 AKT2 EP300	1.15e-03	41	148	3	C0496956
Disease	Breast adenocarcinoma	AKT1 AKT2 EP300	1.15e-03	41	148	3	C0858252
Disease	mitochondrial DNA measurement	COPB1 TWNK NCAPH2 NUP205 BIK SELENOO BICC1	1.38e-03	328	148	7	EFO_0006312
Disease	waist-hip ratio, body mass index	DOCK2 MRM1	1.60e-03	12	148	2	EFO_0004340, EFO_0004343
Disease	bilirubin measurement	TNPO1 TMPRSS6 CARS1 PBX4 SMG5 SBK1 HOOK1 A4GALT	1.81e-03	442	148	8	EFO_0004570
Disease	Benign tumor of pancreas	AKT2 EP300	1.88e-03	13	148	2	C0347284
Disease	CD209 antigen measurement	CELSR2 STKLD1	2.19e-03	14	148	2	EFO_0008077
Disease	mean reticulocyte volume	TNPO1 INTU SRPK1 NCAPH2 URB2 ABCA7 NUP205 GTF3C1 HOOK1 AP2B1 ZBTB40	2.39e-03	799	148	11	EFO_0010701
Disease	IGFBP-3 measurement	CREBBP PANK4 UNC79	2.54e-03	54	148	3	EFO_0004626
Disease	Small cell carcinoma of lung	CREBBP AKT1 EP300	2.54e-03	54	148	3	C0149925
Disease	Diffuse Large B-Cell Lymphoma	CREBBP CLTC EP300	2.68e-03	55	148	3	C0079744
Disease	T-Cell Lymphoma	AKT1 EP300	2.86e-03	16	148	2	C0079772
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	AKT1 BICC1	2.86e-03	16	148	2	DOID:0110861 (implicated_via_orthology)
Disease	prostate cancer (is_implicated_in)	BIK RASSF1 AKT1 AKT2	2.91e-03	117	148	4	DOID:10283 (is_implicated_in)
Disease	Squamous cell carcinoma	ITGA5 CREBBP AKT1 EP300	3.58e-03	124	148	4	C0007137
Disease	very low density lipoprotein cholesterol measurement, esterified cholesterol measurement	PBX4 CELSR2	3.63e-03	18	148	2	EFO_0008317, EFO_0008589
Disease	uric acid measurement	LRRC8C INTU DYNC2H1 TSHR TRAFD1 NFATC1 UNC5CL SELENOO BICC1	3.76e-03	610	148	9	EFO_0004761
Disease	Pancreatic carcinoma	AKT2 EP300	4.04e-03	19	148	2	C0235974
Disease	hydrocephalus (implicated_via_orthology)	STK36 CELSR2	4.04e-03	19	148	2	DOID:10908 (implicated_via_orthology)
Disease	prostate adenocarcinoma (is_implicated_in)	AKT1 AKT2	4.47e-03	20	148	2	DOID:2526 (is_implicated_in)
Disease	sclerosing cholangitis	SGSM1 CREBBP TANGO6	4.49e-03	66	148	3	EFO_0004268
Disease	calcium measurement	TNPO1 CARS1 WDR81 PBX4 TMEM121 EHBP1L1 CELSR2 A4GALT QPCT	4.54e-03	628	148	9	EFO_0004838
Disease	Microcephaly	CARS1 SLC9A6 DYNC1H1	4.68e-03	67	148	3	C0025958
Disease	kidney disease (biomarker_via_orthology)	TGFBR1 NFATC1	4.93e-03	21	148	2	DOID:557 (biomarker_via_orthology)
Disease	Arthrogryposis	VPS33B DYNC1H1	4.93e-03	21	148	2	C0003886

Protein segments in the cluster

Peptide	Gene	Start	Entry
MRELVQPLLALLPDT	URB2	576	Q14146
ILMEEIRFPRTLGPE	AKT1	361	P31749
LILMEEIRFPRTLSP	AKT2	361	P31751
PEELRQALMPTLEAL	EP300	1051	Q09472
PDRLPLQMALTELET	ARHGEF10	586	O15013
RMPIPELDLSELEGL	MLLT11	16	Q13015
EDPNPLIRALAVRTM	AP2B1	96	P63010
MLPLDLRELFRDTPL	A4GALT	141	Q9NPC4
RLSLPMDIRLPQEFL	CDK18	96	Q07002
LREMIQLPGARPILD	FDXR	241	P22570
RLTPSDMPLLELKDI	ASCC2	231	Q9H1I8
EPARELMAVLLTPRF	DEPDC4	6	Q8N2C3
PDLLLQMLKLLDPER	FAM47DP	141	A6NHR8
PDLLLLDEPTNMLDV	ABCF3	346	Q9NUQ8
KPEELRQALMPTLEA	CREBBP	1086	Q92793
RPNRLPLLEFMITDL	CFAP46	1716	Q8IYW2
MKTLRDPSLPLLELQ	ACACA	886	Q13085
EDPNPLIRALAVRTM	AP1B1	96	Q10567
LRLEDMSPERFLSPL	CELSR2	1131	Q9HCU4
QMDLISPLLLPVLLL	DNHD1	2796	Q96M86
LATLMPLPELRELDA	DNHD1	4361	Q96M86
ILMETLLYEQLLEPP	BIK	11	Q13323
ELLPLVLMFELPIAG	BICC1	201	Q9H694
EPMPSLLDVRQLITL	IQCA1	536	Q86XH1
PPMLDVAELLTSLLR	ABCA7	151	Q8IZY2
LGPLAPEMIDSRVLE	CDK5RAP2	1186	Q96SN8
TLELPLIPILAVMES	POLN	426	Q7Z5Q5
LRDLPENLLTKELMP	RALBP1	271	Q15311
IRIDMETELPSLLLP	REC8	106	O95072
PEAITILEAEPIRML	REC8	191	O95072
MPLVLPPELELLSLE	REC8	466	O95072
MSGEPELIELRELAP	RASSF1	1	Q9NS23
MDLLVLLDLIGAPNP	QPCT	241	Q16769
LEMRLPDIPLRQVIA	INTS8	646	Q75QN2
EAMGLPEAVLRAEPL	ITPRIP	486	Q8IWB1
PPISLRRDLEHLMLL	NUP205	431	Q92621
MKEISLLPDNLLRTP	PDK1	91	Q15118
FMDALREPLPATLRI	NSUN2	66	Q08J23
ARLREAGLAPVPMII	UROD	246	P06132
LSRELPLGPADAMEL	INTS1	661	Q8N201
RGLQLPAPLLDSMVE	GTPBP6	401	O43824
MPAERRLPLSFVLDV	JMJD7	101	P0C870
REEDLQGLPLVEMPR	FNDC9	171	Q8TBE3
DDMVLQLLPALSTLP	LRRC75A	216	Q8NAA5
PLRERMELLHSLLPQ	HERC1	856	Q15751
DLNEMILLLPLCRPE	GSTA3	101	Q16772
MAAEDELQLPRLPEL	IGBP1	1	P78318
MEAPAERALPRLQAL	NUPR2	1	A6NF83
MELLSPPLRDVDLTA	MYOD1	1	P15172
LPLTLVPGERFRELM	NAA16	296	Q6N069
ELLEPLMPAIRACLE	COPB1	131	P53618
ILELLTPLQAELMRI	PRAMEF18	426	Q5VWM3
MVALLPFLPDLEELD	LRRC31	106	Q6UY01
VLEIPLLPENSMRAV	NFATC1	516	O95644
SRLLEPADMVLLSVP	EHBP1L1	1111	Q8N3D4
APDLILADLPRNIML	LRRK2	1856	Q5S007
LLDLERTLMLPLTEG	MIGA2	261	Q7L4E1
MDAEGLALLLPPVTL	QPRT	1	Q15274
RKETLQALDMPVLPV	TWNK	41	Q96RR1
LLELMQRIELPLSLP	DQX1	566	Q8TE96
EMDRLERPLVDLPLL	PANK4	411	Q9NVE7
PAEEVPLPRLRNMIE	INTU	391	Q9ULD6
PSMELGRLEIPAELA	MYO15B	421	Q96JP2
LRMLEPEPLAGLDQL	PODNL1	441	Q6PEZ8
DDLLVGAPLLMDRTP	ITGA5	341	P08648
PPDAQLLRLDNMLLA	PBX4	76	Q9BYU1
LRMPPDVIRDILEGV	DYNC2H1	3006	Q8NCM8
SLLDAELMRRPFDLP	CEP104	291	O60308
ELMRRPFDLPLQPLA	CEP104	296	O60308
LNFEEMRALLDSLPP	KLHL14	216	Q9P2G3
GPILEMTLIPETELR	DOCK1	1086	Q14185
PILEMTLIPEAELRK	DOCK2	1091	Q92608
ATLIRLMPLEAGIPD	BTAF1	1211	O14981
ELVPDLKPRLGMTLQ	CYP2R1	476	Q6VVX0
IFLDTLRSMEPPEIL	CRYBG2	766	Q8N1P7
MLPLGSEPALNELLL	CCDC57	1	Q2TAC2
LLERVLMKDIATPIP	CADPS2	781	Q86UW7
LRQPDPVALLMLLVD	BCAS4	21	Q8TDM0
PVLDRADMEKLVIPA	LEFTY2	41	O00292
RLDPMALLELVRVLD	HAS1	241	Q92839
PAEILELTRLLPLMF	GARIN6	111	Q8NEG0
VLADSVLMEQPPLRR	DYNC1H1	1791	Q14204
PDLIEMVLDKLRPEN	IDE	461	P14735
VLLPESIPFLAELME	HEATR1	2101	Q9H583
LREKEPGLMPQVLLV	ENDOV	111	Q8N8Q3
RPILQSLLLPVMDQD	EMC1	621	Q8N766
DPKLNPASAEIMLLR	HOOK1	621	Q9UJC3
RLHFLVIMRDIPELP	FAM135B	256	Q49AJ0
VRLAAPLAVLPMEPL	C1orf127	526	Q8N9H9
QPLRRMLPVDEFLPI	CERCAM	491	Q5T4B2
LPPLVLNREARALGM	DNA2	791	P51530
RSPEMQEERLKLPIL	DHX37	241	Q8IY37
EPALRMFQRLLALEP	SBK1	286	Q52WX2
LFDEMPLIPRTILEE	SACS	796	Q9NZJ4
EPLDMPDITLLQLEG	CCDC184	176	Q52MB2
LESVFRIPPELDMSL	PCGF6	241	Q9BYE7
RIPPELDMSLLLEFI	PCGF6	246	Q9BYE7
ETLLAADPGLPARLM	HGH1	96	Q9BTY7
IIPLVLSPDRDEDLM	MED8	76	Q96G25
LDVFMLTLPLEVELP	SZT2	1616	Q5T011
ELERASLLQILPEML	UTS2	46	O95399
DMEALNVLPPDVLTR	CARS1	226	P49589
RLVLPMDDSEPPLNL	SLC9A6	646	Q92581
SQLLRQIEALDPPMR	TRAFD1	166	O14545
DLPSSLLLPEDMALR	SMG5	721	Q9UPR3
LLLPEDMALRNLPPL	SMG5	726	Q9UPR3
LALARELDIMEPKVP	PSMD2	331	Q13200
QPRMLVTFDEELRPL	PSMD2	826	Q13200
PDIHIMAPLIRSILL	IQCA1L	551	A6NCM1
AELLRMAEARDIPVL	MRM1	86	Q6IN84
SLLPEELEDQMPRLV	MORC4	656	Q8TE76
LFKRIPAEDVPLLLM	POLR3A	226	O14802
PEDRIIDGRDLMPLL	STS	416	P08842
SLEELRLAFRPQMDP	SELENOO	486	Q9BVL4
EASASEMLPLLLPLL	SIGLEC6	6	O43699
PDAARMPAEIVVLLD	SPINDOC	166	Q9BUA3
LPMLELIPEKRATAA	SRPK1	631	Q96SB4
MLQLIRAILKVPEDP	CYB5R1	191	Q9UHQ9
ELPLDPAKLDMLVAL	RHBDL1	101	O75783
ELPISLLTRLALMDP	STK36	1031	Q9NRP7
GLMLAITLLEERLLP	SLC39A5	521	Q6ZMH5
MEAAVAAPRPRLLLL	TGFBR1	1	P36897
PLLLMLGQEDRRVPF	APEH	666	P13798
PPADPRLREDMALLA	ABTB1	231	Q969K4
DALHIPRLLEPEDIM	CLMN	256	Q96JQ2
PLLLNDLLMVLSPRL	CLTC	1416	Q00610
EVLIIPLLPMALVAP	NCAPH2	141	Q6IBW4
LPMLPLADTEKLIRE	SEPTIN1	326	Q8WYJ6
EELLPELLPEMLLSE	TCEAL1	51	Q15170
ELLPEMLLSEERPPQ	TCEAL1	56	Q15170
EPMVLREFLRLASPL	WDFY3	936	Q8IZQ1
LLMLDEDEIHPLLIR	SYNGAP1	56	Q96PV0
MVLEPPREALTGELL	RP1L1	1586	Q8IWN7
ESLEPDLPALRAMGL	SLC27A3	226	Q5K4L6
RNLLPLMLQIDPSDR	STKLD1	271	Q8NE28
VPGLFLLLVALDRME	TMEM121	121	Q9BTD3
NIREPLRMDLADLLT	UBE2L6	116	O14933
NRLPPELFEQLRMLL	UNC5CL	406	Q8IV45
EPLTVLMDSLLPVLG	TANGO6	466	Q9C0B7
PEEMVLLPRQARLFA	VPS13C	2996	Q709C8
ERPAVFAMRLLPVLD	TMEM8B	66	A6NDV4
LMDPVDGPILASLLV	SGSM1	161	Q2NKQ1
LDSDVLDRPLNIMIP	TNPO1	171	Q92973
PLLVLDDVELMPRPL	TOR4A	261	Q9NXH8
RPGDRLLDLDIPMSV	UBP1	141	Q9NZI7
ESLGPLRENPFMLLE	TPRN	51	Q4KMQ1
RRLDPIITEEMPLLE	TRAPPC8	901	Q9Y2L5
ARLRPAAAPLEELTM	GTF3C1	1686	Q12789
ELLPLSELSPPMLIE	UBR2	636	Q8IWV8
VPLEDVDLVLELAPM	PRR23C	71	Q6ZRP0
VRESVLPEDAILPLM	UNC13D	781	Q70J99
HIEDLVMLPTPVLRL	UHMK1	311	Q8TAS1
AVVLDLLMSLPEELP	SNAPC2	231	Q13487
ADLVRPLLPKDMERL	SON	1731	P18583
PSLLRAEALLESPEM	WDR81	216	Q562E7
LMDILPRISHEVLLP	WDR81	1361	Q562E7
LPLDVDLLSMELPEF	VPS33B	146	Q9H267
VLPDMLPDLPVSLVL	TMEM236	121	Q5W0B7
PLDLLMEEIRREPGA	ZBTB40	546	Q9NUA8
LQIPEHRRLMLSPEV	TMPRSS6	156	Q8IU80
ILAVLLPPVMLLIDG	TMEM101	206	Q96IK0
MRPADLLQLVLLLDL	TSHR	1	P16473
LSPDLAAPLLLDIMQ	UNC79	2036	Q9P2D8
LELPLIMLSGLPDTV	LRRC8C	426	Q8TDW0
MELLLPEERLPAAVA	EXD3	321	Q8N9H8