Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	MHC class Ib protein binding	LILRA2 KIR3DL1 KIR3DL2	9.87e-05	16	115	3	GO:0023029
GeneOntologyMolecularFunction	MHC class I receptor activity	LILRA2 KIR3DL1 KIR3DS1	1.43e-04	18	115	3	GO:0032393
GeneOntologyMolecularFunction	MHC class Ib receptor activity	LILRA2 KIR3DL1 KIR3DL2	1.69e-04	19	115	3	GO:0032394
GeneOntologyMolecularFunction	glycosyltransferase activity	SIRT1 STT3B GYS1 ST6GALNAC4 FUT1 TNKS2 ST8SIA4 PLOD1	2.65e-04	288	115	8	GO:0016757
GeneOntologyMolecularFunction	immune receptor activity	FLT3 LILRA2 IFNGR1 KIR3DL1 KIR3DL2 KIR3DS1	3.89e-04	165	115	6	GO:0140375
GeneOntologyMolecularFunction	HLA-B specific inhibitory MHC class I receptor activity	LILRA2 KIR3DL1	4.86e-04	6	115	2	GO:0030109
GeneOntologyBiologicalProcess	developmental growth	FLT3 PDE4D FN1 SEMA7A MYO5B DDR2 SIRT1 EYS BMPR2 LATS1 ARID2 PRKN TNKS2 NDRG4 RASAL1 PCNT FOXC2	9.34e-06	911	113	17	GO:0048589
GeneOntologyBiologicalProcess	regulation of developmental growth	FLT3 FN1 SEMA7A MYO5B SIRT1 BMPR2 LATS1 PRKN TNKS2 RASAL1 FOXC2	2.02e-05	421	113	11	GO:0048638
GeneOntologyBiologicalProcess	positive regulation of cell growth	FN1 SEMA7A MYO5B RPS6KA1 SIRT1 BMPR2 PRKN RASAL1	2.29e-05	213	113	8	GO:0030307
GeneOntologyBiologicalProcess	cellular response to manganese ion	ATP13A2 TH PRKN	3.40e-05	12	113	3	GO:0071287
GeneOntologyBiologicalProcess	positive regulation of developmental growth	FLT3 FN1 SEMA7A MYO5B SIRT1 BMPR2 PRKN RASAL1	5.05e-05	238	113	8	GO:0048639
GeneOntologyBiologicalProcess	positive regulation of growth	FLT3 FN1 SEMA7A MYO5B RPS6KA1 SIRT1 BMPR2 PRKN RASAL1	1.05e-04	339	113	9	GO:0045927
GeneOntologyBiologicalProcess	carbohydrate derivative metabolic process	PDE4D CES1 OGDH STT3B CBR4 ACSL1 TH BMPR2 SCCPDH ACOT11 PRKN ST6GALNAC4 FUT1 ST8SIA4 FBXO27 PLOD1 UAP1L1 MAN1B1	1.18e-04	1226	113	18	GO:1901135
GeneOntologyBiologicalProcess	growth	FLT3 PDE4D FN1 SEMA7A MYO5B RPS6KA1 DDR2 SIRT1 EYS BMPR2 LATS1 ARID2 PRKN TNKS2 NDRG4 RASAL1 PCNT FOXC2	1.29e-04	1235	113	18	GO:0040007
Domain	-	PDCD1 FLT3 LILRA2 SDK2 FN1 SEMA7A BTNL8 PLXND1 PKHD1L1 IFNGR1 PTPRG KIR3DL1 KIR3DL2 KIR3DS1	6.31e-05	663	116	14	2.60.40.10
Domain	Ig-like_fold	PDCD1 FLT3 LILRA2 SDK2 FN1 SEMA7A BTNL8 PLXND1 PKHD1L1 IFNGR1 PTPRG KIR3DL1 KIR3DL2 KIR3DS1	1.23e-04	706	116	14	IPR013783
Domain	Ndr	NDRG2 NDRG4	2.28e-04	4	116	2	PF03096
Domain	NDRG	NDRG2 NDRG4	2.28e-04	4	116	2	IPR004142
Pubmed	Allelic polymorphism synergizes with variable gene content to individualize human KIR genotype.	KIR3DL1 KIR3DL2 KIR3DS1	3.62e-08	3	116	3	11859120
Pubmed	Analysis of killer immunoglobulin-like receptor genes in ankylosing spondylitis.	KIR3DL1 KIR3DL2 KIR3DS1	3.62e-08	3	116	3	19019897
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	NCAPD3 DST COQ8A CDC16 ARID2 PAN2 ANKRD17 ECI2 PCNT	4.25e-08	212	116	9	33853758
Pubmed	Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.	KIR3DL1 KIR3DL2 KIR3DS1	1.44e-07	4	116	3	27455421
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	NCAPD3 PDE4D ARFGEF2 XPO1 STT3B DHX9 DOCK5 ANKRD17	4.19e-07	202	116	8	33005030
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	CLUAP1 PHACTR2 PLXND1 ACOT11 PAN2 ANKRD17	1.25e-06	102	116	6	9734811
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SMG1 NCAPD3 SDK2 PLXND1 INTS5 DST COQ8A PAN2 ANKRD17 NDRG4 ARAP1	1.70e-06	529	116	11	14621295
Pubmed	Human diversity in killer cell inhibitory receptor genes.	KIR3DL1 KIR3DL2 KIR3DS1	2.00e-06	8	116	3	9430221
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	FN1 CCDC186 INPP5B PSMA5 ARFGEF2 NBEA PLXND1 PKHD1L1 DMXL1 DHX9 DOCK5 DST MRPS9	2.08e-06	777	116	13	35844135
Pubmed	Alternatively spliced forms of human killer inhibitory receptors.	KIR3DL1 KIR3DL2 KIR3DS1	2.99e-06	9	116	3	8662091
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RAD51 SEMA7A LONRF1 ARFGEF2 TMCO6 PLXND1 ATP13A2 INTS5 DST NISCH NAV1 FUT1 RASAL1 ARAP1 PCNT	4.25e-06	1105	116	15	35748872
Pubmed	Targeted disruption of beta-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex.	CYP11B2 TH HSD3B2	5.85e-06	11	116	3	18599507
Pubmed	[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].	KIR3DL1 KIR3DL2 KIR3DS1	7.78e-06	12	116	3	17490516
Pubmed	[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].	KIR3DL1 KIR3DL2 KIR3DS1	7.78e-06	12	116	3	20137308
Pubmed	Defining the membrane proteome of NK cells.	NCAPD3 ARFGEF2 XPO1 STT3B DHX9 ACSL1 INTS5 SCCPDH NISCH GYS1 ANKRD17 ELAVL1 ECI2 MAN1B1 PCNT	8.25e-06	1168	116	15	19946888
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	RAD51 DENND5B HIKESHI INPP5B COX15 SPACA9 XPO1 SIRT1 STT3B ACSL1 CDC16 ARID2 MRPS9 ANKRD17 ELAVL1 PCNT	8.85e-06	1327	116	16	32694731
Pubmed	Loss of Sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays PARK2 translocation to mitochondria.	SIRT1 PRKN	1.10e-05	2	116	2	25529796
Pubmed	No association of KIR3DL1 or KIR3DS1 or their alleles with ankylosing spondylitis.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	19874556
Pubmed	Dopamine triggers heterosynaptic plasticity.	GAD2 TH	1.10e-05	2	116	2	23595734
Pubmed	Evaluation of KIR3DL1/KIR3DS1 polymorphism in Behçet's disease.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	27708262
Pubmed	Exposure to cocaine regulates inhibitory synaptic transmission from the ventral tegmental area to the nucleus accumbens.	GAD2 TH	1.10e-05	2	116	2	23918773
Pubmed	CD158k and PD-1 expressions define heterogeneous subtypes of Sezary syndrome.	PDCD1 KIR3DL2	1.10e-05	2	116	2	34570200
Pubmed	Different NK cell surface phenotypes defined by the DX9 antibody are due to KIR3DL1 gene polymorphism.	KIR3DL1 KIR3DL2	1.10e-05	2	116	2	11207248
Pubmed	Investigation of killer cell immunoglobulin-like receptor gene diversity in KIR3DL1 and KIR3DS1 in a transplant population.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	18331531
Pubmed	Contribution of KIR3DL1/3DS1 to ankylosing spondylitis in human leukocyte antigen-B27 Caucasian populations.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	16805919
Pubmed	No association of alcohol dependence with HOMER 1 and 2 genetic variants.	HOMER2 HOMER1	1.10e-05	2	116	2	20333726
Pubmed	Role of natural killer cells in a cohort of elite suppressors: low frequency of the protective KIR3DS1 allele and limited inhibition of human immunodeficiency virus type 1 replication in vitro.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	19211742
Pubmed	Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	35192601
Pubmed	Role of FN1 and GREB1 gene polymorphisms in endometriosis.	FN1 GREB1	1.10e-05	2	116	2	31115525
Pubmed	Evaluation of KIR3DL1/KIR3DS1 allelic polymorphisms in Kenyan children with endemic Burkitt lymphoma.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	37647275
Pubmed	Localization and expression of group I metabotropic glutamate receptors in the mouse striatum, globus pallidus, and subthalamic nucleus: regulatory effects of MPTP treatment and constitutive Homer deletion.	HOMER2 HOMER1	1.10e-05	2	116	2	17553998
Pubmed	Association of the KIR3DS1013 and KIR3DL1004 alleles with susceptibility to ankylosing spondylitis.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	20131260
Pubmed	Reciprocal Homer1a and Homer2 Isoform Expression Is a Key Mechanism for Muscle Soleus Atrophy in Spaceflown Mice.	HOMER2 HOMER1	1.10e-05	2	116	2	35008503
Pubmed	Protective genotypes in HIV infection reflect superior function of KIR3DS1+ over KIR3DL1+ CD8+ T cells.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	25112829
Pubmed	Unusual selection on the KIR3DL1/S1 natural killer cell receptor in Africans.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	17694054
Pubmed	Behavioral and neurochemical phenotyping of Homer1 mutant mice: possible relevance to schizophrenia.	HOMER2 HOMER1	1.10e-05	2	116	2	16011574
Pubmed	Contribution of functional KIR3DL1 to ankylosing spondylitis.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	20818412
Pubmed	Inhibition of neurite outgrowth by reduced level of NDRG4 protein in antisense transfected PC12 cells.	NDRG2 NDRG4	1.10e-05	2	116	2	11978393
Pubmed	Diagnostic Potential of Differentially Expressed Homer1 and Homer2 in Ischemic Stroke.	HOMER2 HOMER1	1.10e-05	2	116	2	27832625
Pubmed	KIR3DL1 and KIR3DL2 gene copy number variation in axial spondyloarthritis.	KIR3DL1 KIR3DL2	1.10e-05	2	116	2	25940819
Pubmed	Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer.	KIR3DL1 KIR3DL2	1.10e-05	2	116	2	8777725
Pubmed	A method for killer-cell immunoglobulin-like receptor (KIR) 3DL1/3DS1 genotyping using DNA recovered from frozen plasma.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	23524032
Pubmed	Diversity of the p70 killer cell inhibitory receptor (KIR3DL) family members in a single individual.	KIR3DL1 KIR3DL2	1.10e-05	2	116	2	10774747
Pubmed	Allele diversity of the killer cell immunoglobulin-like receptors KIR3DL1/S1 and the combination with their HLA ligands in Mexican Mestizos from Mexico City.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	30365992
Pubmed	Imbalances in prefrontal cortex CC-Homer1 versus CC-Homer2 expression promote cocaine preference.	HOMER2 HOMER1	1.10e-05	2	116	2	23658151
Pubmed	Functional polymorphism of the KIR3DL1/S1 receptor on human NK cells.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	17182560
Pubmed	Genetic control of variegated KIR gene expression: polymorphisms of the bi-directional KIR3DL1 promoter are associated with distinct frequencies of gene expression.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	19008943
Pubmed	Combinatorial targeting of XPO1 and FLT3 exerts synergistic anti-leukemia effects through induction of differentiation and apoptosis in FLT3-mutated acute myeloid leukemias: from concept to clinical trial.	FLT3 XPO1	1.10e-05	2	116	2	29773601
Pubmed	HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	19386717
Pubmed	Myo5b Transports Fibronectin-Containing Vesicles and Facilitates FN1 Secretion from Human Pleural Mesothelial Cells.	FN1 MYO5B	1.10e-05	2	116	2	35563212
Pubmed	Putative role of KIR3DL1/3DS1 alleles and HLA-Bw4 ligands with end stage renal disease and long term renal allograft survival.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	28942035
Pubmed	The profile of KIR3DL1 and KIR3DS1 alleles in an African American population resembles that found in African populations.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	20230527
Pubmed	Development of a PCR-SSOP approach capable of defining the natural killer cell inhibitory receptor (KIR) gene sequence repertoires.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	11098931
Pubmed	Expression and regulation of Homer in human skeletal muscle during neuromuscular junction adaptation to disuse and exercise.	HOMER2 HOMER1	1.10e-05	2	116	2	21885651
Pubmed	Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes.	KIR3DL1 KIR3DS1	1.10e-05	2	116	2	19411600
Pubmed	Association of a polymorphism in the Homer1 gene with cocaine dependence in an African American population.	HOMER2 HOMER1	1.10e-05	2	116	2	16314758
Pubmed	Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.	KIR3DL1 KIR3DL2 KIR3DS1	1.28e-05	14	116	3	19875891
Pubmed	HOXA5 localization in postnatal and adult mouse brain is suggestive of regulatory roles in postmitotic neurons.	GAD2 PLXND1 TH	1.28e-05	14	116	3	27650319
Pubmed	[Genotype and haplotype analysis of killer cell immunoglobulin-like receptors in ankylosing spondylitis].	KIR3DL1 KIR3DL2 KIR3DS1	1.28e-05	14	116	3	19489269
Pubmed	Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.	KIR3DL1 KIR3DL2 KIR3DS1	1.28e-05	14	116	3	15896204
Pubmed	Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.	KIR3DL1 KIR3DL2 KIR3DS1	1.28e-05	14	116	3	18945962
Pubmed	Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.	KIR3DL1 KIR3DL2 KIR3DS1	1.60e-05	15	116	3	20082646
Pubmed	[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].	KIR3DL1 KIR3DL2 KIR3DS1	1.60e-05	15	116	3	20356536
Pubmed	Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.	KIR3DL1 KIR3DL2 KIR3DS1	1.60e-05	15	116	3	19926642
Pubmed	Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.	KIR3DL1 KIR3DL2 KIR3DS1	1.60e-05	15	116	3	20643584
Pubmed	Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.	KIR3DL1 KIR3DL2 KIR3DS1	1.60e-05	15	116	3	19326408
Pubmed	Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.	KIR3DL1 KIR3DL2 KIR3DS1	1.96e-05	16	116	3	19897003
Pubmed	Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.	KIR3DL1 KIR3DL2 KIR3DS1	1.96e-05	16	116	3	19000141
Pubmed	Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.	KIR3DL1 KIR3DL2 KIR3DS1	1.96e-05	16	116	3	20670355
Pubmed	Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.	KIR3DL1 KIR3DL2 KIR3DS1	1.96e-05	16	116	3	18668235
Pubmed	Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.	KIR3DL1 KIR3DL2 KIR3DS1	1.96e-05	16	116	3	19309280
Pubmed	Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.	KIR3DL1 KIR3DL2 KIR3DS1	1.96e-05	16	116	3	19527230
Pubmed	Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.	KIR3DL1 KIR3DL2 KIR3DS1	1.96e-05	16	116	3	20652381
Pubmed	Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.	KIR3DL1 KIR3DL2 KIR3DS1	1.96e-05	16	116	3	19279038
Pubmed	No association of KIR genes with Behcet's disease.	KIR3DL1 KIR3DL2 KIR3DS1	1.96e-05	16	116	3	17868255
Pubmed	A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris.	KIR3DL1 KIR3DL2 KIR3DS1	1.96e-05	16	116	3	18643961
Pubmed	Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.	KIR3DL1 KIR3DL2 KIR3DS1	1.96e-05	16	116	3	20331834
Pubmed	HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop.	KIR3DL1 KIR3DL2 KIR3DS1	1.96e-05	16	116	3	20210919
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	PDE4D FN1 MYO5B ARFGEF2 NBEA XPO1 OGDH DHX9 DST NISCH STON2 MRPS9 NAV1 ELAVL1 HOMER1 RASAL1	2.23e-05	1431	116	16	37142655
Pubmed	[Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoietic stem cell transplantation].	KIR3DL1 KIR3DL2 KIR3DS1	2.38e-05	17	116	3	19968064
Pubmed	Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.	KIR3DL1 KIR3DL2 KIR3DS1	2.38e-05	17	116	3	20878400
Pubmed	Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.	KIR3DL1 KIR3DL2 KIR3DS1	2.38e-05	17	116	3	20650299
Pubmed	Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.	KIR3DL1 KIR3DL2 KIR3DS1	2.38e-05	17	116	3	19032228
Pubmed	The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia.	KIR3DL1 KIR3DL2 KIR3DS1	2.38e-05	17	116	3	20173792
Pubmed	Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru.	KIR3DL1 KIR3DL2 KIR3DS1	2.38e-05	17	116	3	20483367
Pubmed	Targeted Disruption of Lats1 and Lats2 in Mice Impairs Adrenal Cortex Development and Alters Adrenocortical Cell Fate.	CYP11B2 TH LATS1	2.38e-05	17	116	3	32243503
Pubmed	[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].	KIR3DL1 KIR3DL2 KIR3DS1	2.38e-05	17	116	3	19218127
Pubmed	Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.	KIR3DL1 KIR3DL2 KIR3DS1	2.38e-05	17	116	3	19450876
Pubmed	Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.	KIR3DL1 KIR3DL2 KIR3DS1	2.38e-05	17	116	3	19761533
Pubmed	Global landscape of HIV-human protein complexes.	NCAPD3 ARFGEF2 XPO1 SIRT1 MRPS9 ANKRD17 KIR3DL1 KIR3DL2 PLOD1	2.38e-05	457	116	9	22190034
Pubmed	High-Confidence Interactome for RNF41 Built on Multiple Orthogonal Assays.	NAV1 ZNF281 HOMER2 HOMER1	2.40e-05	50	116	4	29560723
Pubmed	Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.	KIR3DL1 KIR3DL2 KIR3DS1	2.84e-05	18	116	3	19630074
Pubmed	Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians.	KIR3DL1 KIR3DL2 KIR3DS1	2.84e-05	18	116	3	19046302
Pubmed	Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes.	KIR3DL1 KIR3DL2 KIR3DS1	2.84e-05	18	116	3	20580654
Pubmed	Adrenal Development in Mice Requires GATA4 and GATA6 Transcription Factors.	CYP11B2 TH HSD3B2	2.84e-05	18	116	3	25933105
Pubmed	Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.	KIR3DL1 KIR3DL2 KIR3DS1	2.84e-05	18	116	3	20519398
Pubmed	Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.	KIR3DL1 KIR3DL2 KIR3DS1	2.84e-05	18	116	3	19846535
Pubmed	Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela.	KIR3DL1 KIR3DL2 KIR3DS1	2.84e-05	18	116	3	20210918
Pubmed	The chromatin-remodeling subunit Baf200 promotes homology-directed DNA repair and regulates distinct chromatin-remodeling complexes.	RAD51 ARID2	3.30e-05	3	116	2	28381560
Pubmed	Role of angiotensin II-induced rapid response genes in the regulation of enzymes needed for aldosterone synthesis.	CYP11B2 HSD3B2	3.30e-05	3	116	2	19158234
Interaction	TOB2 interactions	RPS6KA1 XPO1 PAN2 ELAVL1	4.39e-06	20	114	4	int:TOB2
Interaction	SPIDR interactions	RAD51 FANCM DHX9 PRKN	9.46e-06	24	114	4	int:SPIDR
Cytoband	19q13.4	LILRA2 KIR3DL1 KIR3DL2 KIR3DS1	5.02e-05	79	116	4	19q13.4
Cytoband	9q34	SPACA9 ST6GALNAC4 MAN1B1	3.55e-04	54	116	3	9q34
GeneFamily	Homer scaffolding proteins	HOMER2 HOMER1	6.08e-05	3	82	2	871
GeneFamily	CD molecules\|Killer cell immunoglobulin like receptors	KIR3DL1 KIR3DL2 KIR3DS1	6.99e-05	18	82	3	620
GeneFamily	WD repeat domain containing\|BEACH domain containing	WDR81 NBEA	7.17e-04	9	82	2	1230
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	PDCD1 FLT3 LILRA2 SEMA7A IFNGR1 KIR3DL1 KIR3DL2	2.07e-03	394	82	7	471
GeneFamily	Parkinson disease associated genes	ATP13A2 PRKN	2.34e-03	16	82	2	672
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	RAD51 FANCM	3.66e-03	20	82	2	548
GeneFamily	Sialyltransferases	ST6GALNAC4 ST8SIA4	3.66e-03	20	82	2	438
Coexpression	GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_UP	MYO5B FSCN3 WDR81 PKHD1L1 DOCK5 SCCPDH HSD3B2 UNC80	3.14e-06	200	116	8	M5706
Coexpression	GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN	HIKESHI ATP13A2 SCCPDH NISCH GYS1 ST6GALNAC4 HOMER1 NDRG4	1.12e-05	238	116	8	M1098
Coexpression	GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN	HIKESHI ATP13A2 SCCPDH NISCH GYS1 ST6GALNAC4 HOMER1 NDRG4	1.56e-05	249	116	8	MM1092
Coexpression	GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN	FN1 RPS6KA1 IFNGR1 COQ8A FBXO27 UAP1L1 RASAL1	1.90e-05	185	116	7	M8238
Coexpression	GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN	DENND5B PKHD1L1 NPHP3 GYS1 PAN2 PRKN TMEM63A	2.33e-05	191	116	7	M4935
Coexpression	GSE40685_NAIVE_CD4_TCELL_VS_FOXP3_KO_TREG_PRECURSOR_DN	PDE4D DDR2 SLC39A4 PLXND1 INTS5 PRKN RASAL1	2.66e-05	195	116	7	M9309
Coexpression	GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP	TMCO6 XPO1 STT3B CBR4 BMPR2 NISCH ELAVL1	2.66e-05	195	116	7	M3138
Coexpression	GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_DN	INPP5B PSMA5 DMXL1 ACSL1 NISCH ST8SIA4 MARCO	2.94e-05	198	116	7	M5259
Coexpression	GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_DN	RAD51 PDCD1 PHACTR2 SEMA7A PLXND1 STT3B IFNGR1	3.13e-05	200	116	7	M5052
Coexpression	GSE26912_TUMORICIDAL_VS_CTRL_MACROPHAGE_DN	RAD51 TBXAS1 SEMA7A INPP5B GYS1 NDRG4 PCNT	3.13e-05	200	116	7	M8206
Coexpression	GSE24210_IL35_TREATED_VS_UNTREATED_TCONV_CD4_TCELL_DN	SMG1 PDCD1 SIRT1 TH BMPR2 PAN2 RASAL1	3.13e-05	200	116	7	M7850
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B HHATL MTMR6 STON2 GREB1 ST8SIA4	2.21e-08	179	115	8	d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B HHATL EYS MTMR6 GREB1 ST8SIA4	3.23e-08	188	115	8	8de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCell	Sepsis-URO-Myeloid-cDC1\|URO / Disease, condition lineage and cell class	FLT3 NDRG2 IFNGR1 C1orf21 DST NAV1 FBXO27 HOMER2	5.22e-08	200	115	8	c5ca81218be40b30e2f9252c1a004cb95d988447
ToppCell	URO-Myeloid-cDC1\|URO / Disease, Lineage and Cell Type	FLT3 NDRG2 IFNGR1 DST NAV1 FBXO27 HOMER2	3.40e-07	173	115	7	57f4e9f39ef6e02dca76f3dd0b39a0871917ed5a
ToppCell	Leuk-UTI-Myeloid-cDC1\|Leuk-UTI / Disease, Lineage and Cell Type	FLT3 NDRG2 C1orf21 DST NAV1 FBXO27 HOMER2	3.40e-07	173	115	7	226bb8d881f32d65c60f5e4c034c6d465f8e7ba5
ToppCell	metastatic_Brain-Myeloid_cells-CD141+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	PDCD1 FLT3 SEMA7A NDRG2 C1orf21 FBXO27 HOMER2	3.53e-07	174	115	7	5ec8a48a390379d6c422120dce46437a77da67cc
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_10\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLT3 SEMA7A C1orf21 NAV1 FBXO27 HOMER2 L3MBTL4	4.44e-07	180	115	7	32d871738a24071b70084a7e80148a516110c78b
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_10\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLT3 SEMA7A C1orf21 NAV1 FBXO27 HOMER2 L3MBTL4	4.44e-07	180	115	7	067ca8a15228c7f3b3bc7aecbc9b1611ca05e176
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B HHATL EYS STON2 ST8SIA4	4.79e-07	182	115	7	08aff7112c9dac0ef5540300516a604782b21169
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B HHATL EYS MTMR6 ST8SIA4	4.97e-07	183	115	7	04d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCell	ILEUM-non-inflamed-(1)_T_cell-(1)_T_(gd)\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	GAD2 DOCK5 SCCPDH C1orf21 ECI2 KIR3DL1 KIR3DL2	5.75e-07	187	115	7	e5713a7bda53d1d5178ab4e0dbadc2292b6005bc
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDK2 DST ACOT11 NISCH NAV1 PRKN UNC80	5.95e-07	188	115	7	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B EYS MTMR6 GREB1 ST8SIA4	6.39e-07	190	115	7	39ab890104b4264c68a968f920f4ccd84f0bc681
ToppCell	ILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FN1 NDRG2 PKHD1L1 DOCK5 STON2 L3MBTL4 FOXC2	6.86e-07	192	115	7	d43caf42ec744e895137f31ef65a990e250669d2
ToppCell	normal_Lung-Myeloid_cells-CD141+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	PDCD1 FLT3 SEMA7A NDRG2 C1orf21 NAV1 FBXO27	7.35e-07	194	115	7	d21461682fa755f588afe073abb6a777f339c4cc
ToppCell	distal-Hematologic-Myeloid_Dendritic_Type_2-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TBXAS1 FLT3 LILRA2 NDRG2 DOCK5 ST8SIA4 RASAL1	7.61e-07	195	115	7	7606b8b40e704bb5447ac57ccf8698794e9c7890
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-MEPE-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 FLT3 MYO5B HHATL EYS GREB1 ST8SIA4	9.02e-07	200	115	7	d4161fcbbe47236aac4a077c0994887e765b0b47
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-MEPE\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 FLT3 MYO5B HHATL EYS GREB1 ST8SIA4	9.02e-07	200	115	7	0d0c69758370d3c44ffe6640e332b6118fc5ce58
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-MEPE--L4-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 FLT3 MYO5B HHATL EYS GREB1 ST8SIA4	9.02e-07	200	115	7	c546fa80876640bd57a5252df611977009bef9e8
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 FLT3 PHACTR2 MYO5B HHATL STON2 ST8SIA4	9.02e-07	200	115	7	107854f4855fc99c9f7e737eb246f0d868e6c5fd
ToppCell	Sepsis-ICU-NoSEP-Myeloid-cDC1\|ICU-NoSEP / Disease, condition lineage and cell class	FLT3 NDRG2 C1orf21 DST NAV1 FBXO27 HOMER2	9.02e-07	200	115	7	511e642575182fb678df6791ee6539b0ced3eb17
ToppCell	Sepsis-Leuk-UTI-Myeloid-cDC1\|Leuk-UTI / Disease, condition lineage and cell class	FLT3 NDRG2 C1orf21 DST NAV1 FBXO27 HOMER2	9.02e-07	200	115	7	186852d54eced4c036876cc891773605068b56b5
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_11\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLT3 NDRG2 DST NAV1 FBXO27 HOMER2	4.19e-06	163	115	6	a09449a502627aa369db600dba5bda93de7ce5c0
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_11\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLT3 NDRG2 DST NAV1 FBXO27 HOMER2	4.34e-06	164	115	6	ed888b55d9c685096fd785878fcb264f4fee88d6
ToppCell	356C-Myeloid-Dendritic-cDC1\|356C / Donor, Lineage, Cell class and subclass (all cells)	NCAPD3 FLT3 SEMA7A NDRG2 NAV1 FBXO27	4.65e-06	166	115	6	0590e404f45afce90e20f93f90a3def83949c66b
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_11\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLT3 NDRG2 DST NAV1 FBXO27 HOMER2	4.65e-06	166	115	6	b1bebcbe17386cb102b11d551e62d46156ce0c68
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_11\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLT3 NDRG2 DST NAV1 FBXO27 HOMER2	4.81e-06	167	115	6	e44743b20a7435c579d8e999ddc4ca119d6753f2
ToppCell	Bac-SEP-Myeloid-cDC1\|Bac-SEP / Disease, Lineage and Cell Type	FLT3 NDRG2 C1orf21 DST NAV1 FBXO27	5.89e-06	173	115	6	f88269327441858ddb8c49b9dd619b76fd53b1da
ToppCell	droplet-Heart-HEART-1m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO5B WDR81 SLC39A4 PKHD1L1 FBXO27 FOXC2	5.89e-06	173	115	6	9dc7746a84f0e268a7c061e1bbcd5e31903034dc
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|356C / Donor, Lineage, Cell class and subclass (all cells)	PDCD1 CLUAP1 DMXL1 BMPR2 COQ8A HOMER2	5.89e-06	173	115	6	e3cb7c8c09f937da6b8d673e9adfec5d94a15548
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B HHATL STON2 ST8SIA4	6.50e-06	176	115	6	682a1dfcc507ec540f5fadf08e872533ea9f0291
ToppCell	IIH-mDC1-\|IIH / Condition, Cell_class and T cell subcluster	FLT3 NDRG2 C1orf21 NAV1 FBXO27 FOXC2	6.50e-06	176	115	6	bb80a3e595d071f6cc8b042984b8d9490e377eef
ToppCell	IIH-mDC1\|IIH / Condition, Cell_class and T cell subcluster	FLT3 NDRG2 C1orf21 NAV1 FBXO27 FOXC2	6.50e-06	176	115	6	a75dc132a1061006fd1cb305bd314784fca07ea6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B TH STON2 ST8SIA4	6.72e-06	177	115	6	5e0fca9bd5e5ffe6d39f5bcd81f36512f3b0cb1b
ToppCell	CTRL-Myeloid-cDC\|Myeloid / Disease state, Lineage and Cell class	PDCD1 FLT3 NDRG2 C1orf21 ST8SIA4 RASAL1	7.88e-06	182	115	6	ee137574b8f0e684a4a7cb26226877c471cae433
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B HHATL EYS ST8SIA4	7.88e-06	182	115	6	a3c5c0eff527c8d3848acda14af8f9e99c69b0de
ToppCell	10x5'-lymph-node_spleen-Myeloid_Dendritic-DC1\|lymph-node_spleen / Manually curated celltypes from each tissue	FLT3 NDRG2 C1orf21 DST NAV1 FBXO27	8.13e-06	183	115	6	c9e3d91f4c3395a73295b92e25608e0effb5d241
ToppCell	Control-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	FLT3 SEMA7A NDRG2 C1orf21 ST8SIA4 FBXO27	8.38e-06	184	115	6	c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLT3 NDRG2 C1orf21 DST NAV1 FBXO27	8.38e-06	184	115	6	667846c422cfa27e949a24844a305df859cb6760
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B HHATL STON2 ST8SIA4	8.65e-06	185	115	6	f4ac62009c0ad3346e71b809e17727303c4df153
ToppCell	Control-Myeloid-cDC1\|World / Disease state, Lineage and Cell class	FLT3 SEMA7A NDRG2 C1orf21 ST8SIA4 FBXO27	8.92e-06	186	115	6	3de803dee3ef10eb85a2b47d3f93385214e5b0ff
ToppCell	Control-Myeloid-cDC1\|Control / Disease state, Lineage and Cell class	FLT3 SEMA7A NDRG2 C1orf21 ST8SIA4 FBXO27	8.92e-06	186	115	6	b05c394aa3573ba855abc3066739ca193883b0c3
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B HHATL EYS ST8SIA4	8.92e-06	186	115	6	6379609b7ace80683f5754b16aa77f11b43766ae
ToppCell	367C-Myeloid-Dendritic-cDC1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PDCD1 FLT3 SEMA7A C1orf21 ST8SIA4 FBXO27	9.19e-06	187	115	6	3748203b62abf51b74dfcfc4f18b3ba831b63a96
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B HHATL EYS ST8SIA4	9.19e-06	187	115	6	d413fb4b1531b297af5012a392b88128510c2de8
ToppCell	IPF-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	FLT3 SEMA7A NDRG2 C1orf21 ST8SIA4 FBXO27	9.48e-06	188	115	6	47bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCell	(7)_DC_1\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	FLT3 NDRG2 C1orf21 DST NAV1 FBXO27	9.48e-06	188	115	6	832887afa4a54ed80906bc02176d646529c13398
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 PHACTR2 MYO5B EYS ST8SIA4	1.01e-05	190	115	6	d19bc44310c53726e2f5f6a2bd377bbbf1d1983f
ToppCell	Monocytes-Tissue-resident_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	TBXAS1 FN1 NDRG2 IFNGR1 DST NAV1	1.01e-05	190	115	6	07215e8f292cb54c670037aaf28393cddbe5548c
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B EYS GREB1 ST8SIA4	1.01e-05	190	115	6	3f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B HHATL EYS ST8SIA4	1.01e-05	190	115	6	305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B HHATL EYS ST8SIA4	1.01e-05	190	115	6	8c9c230a509afaeee50644153974a5642b01a2b8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B HHATL EYS ST8SIA4	1.01e-05	190	115	6	e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLT3 CES1 NDRG2 DST NAV1 HOMER2	1.04e-05	191	115	6	2699e9bb872f2b561bb976dfdc2746e359bc9daf
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLT3 CES1 NDRG2 DST NAV1 HOMER2	1.04e-05	191	115	6	4b94c8b0183ae07d173646b7e7e1d9db04ec9637
ToppCell	COPD-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	FLT3 SEMA7A NDRG2 C1orf21 ST8SIA4 FBXO27	1.04e-05	191	115	6	3480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCell	COPD-Myeloid-DC_Mature\|Myeloid / Disease state, Lineage and Cell class	FLT3 PTPRG NAV1 ST8SIA4 HOMER2 L3MBTL4	1.07e-05	192	115	6	baebd462f464e7d0e462d07a74bb5d685a9fc3b6
ToppCell	droplet-Heart-nan-24m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTRT3 MYO5B HHATL COQ8A HOMER1 NDRG4	1.07e-05	192	115	6	f6a4e348406a852ace9fb21db8fbdff539217645
ToppCell	droplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTRT3 MYO5B HHATL COQ8A HOMER1 NDRG4	1.07e-05	192	115	6	1a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B HHATL EYS ST8SIA4	1.07e-05	192	115	6	0003d7ef9a8e521e70ac33c63aad843d9b6215c2
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	DENND5B PDE4D PTPRG ANKRD17 PRKN L3MBTL4	1.07e-05	192	115	6	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	PHACTR2 SDK2 PDE4D FN1 DST PLEKHH2	1.07e-05	192	115	6	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 PHACTR2 MYO5B EYS GREB1	1.10e-05	193	115	6	4979862c0c16e6b4baa4c79894f1d237c861f5a5
ToppCell	URO\|World / Disease, Lineage and Cell Type	LILRA2 CES1 PLXND1 DOCK5 ACSL1 MARCO	1.10e-05	193	115	6	421dc0996c6c973f88e90197b651255ae4dd13a2
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 PHACTR2 MYO5B EYS ST8SIA4	1.10e-05	193	115	6	53bcd50892c379b2a571751f6eb1062436339fe7
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 MYO5B HHATL EYS ST8SIA4	1.10e-05	193	115	6	c4b22b62f3cc7bf0ec0eba76e1504c236290bbc9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 PLXND1 PKHD1L1 BMPR2 C1orf21 NAV1	1.10e-05	193	115	6	287e756d5fd3bd2931c168da24beaa0d02a350ae
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 PHACTR2 MYO5B EYS L3MBTL4	1.13e-05	194	115	6	83863da11dfbe59b2d0a2c08db40b537c150588c
ToppCell	(7)_MNP-(7)_DC_1\|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)	FLT3 NDRG2 C1orf21 DST NAV1 FBXO27	1.13e-05	194	115	6	8dbe0188e2af6f14b3b44e5213fbdd581128082f
ToppCell	distal-2-Hematologic-Myeloid_Dendritic_Type_2\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FLT3 LILRA2 DOCK5 ST8SIA4 HOMER2 RASAL1	1.13e-05	194	115	6	6881cfe12837a32e598535a564e4c31d4846167b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 PHACTR2 MYO5B EYS GREB1	1.13e-05	194	115	6	e5990880961d2469759ce4b3b20ae93ace3ebd1f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GAD2 FLT3 PHACTR2 MYO5B EYS L3MBTL4	1.13e-05	194	115	6	1bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 PLXND1 PKHD1L1 BMPR2 C1orf21 NAV1	1.20e-05	196	115	6	22767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 PLXND1 PKHD1L1 BMPR2 C1orf21 NAV1	1.20e-05	196	115	6	adee900dcd16dbaba15c58bdcace09ba20214950
ToppCell	mild_COVID-19-cDC\|mild_COVID-19 / disease group, cell group and cell class (v2)	FLT3 CES1 NDRG2 DST NAV1 HOMER2	1.24e-05	197	115	6	44ebd3f967779bb7753fc6dcd9fde6d682f9ccd6
ToppCell	(0)_NK_cells-(0)_NK_FCGR3Apos\|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	TBXAS1 PDE4D DOCK5 C1orf21 KIR3DL1 KIR3DL2	1.27e-05	198	115	6	eba39656c6f699ab297b652ded8cb9727b49593c
ToppCell	distal-3-Hematologic-Myeloid_Dendritic_Type_1\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FLT3 SEMA7A NDRG2 NAV1 ST8SIA4 FBXO27	1.27e-05	198	115	6	b21227c7366ef79b36048509a91d2d35fd5e4956
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TBXAS1 FLT3 PLXND1 ST8SIA4 MARCO ARAP1	1.31e-05	199	115	6	1413156b7be5373fd02bbe39ec50ccfe165fa6d1
ToppCell	Mild-Myeloid-Macrophages-FCN1+SPP1+\|Mild / Condition, Lineage, Cell class and cell subclass	TBXAS1 FN1 CES1 ACSL1 DST MARCO	1.31e-05	199	115	6	2cbaef86af870a228cb46895dd765ea8894c83c5
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TBXAS1 FN1 CES1 ACSL1 DST MARCO	1.31e-05	199	115	6	8e9862907b15809d083216e7d6a0f435015e5d15
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1--L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 FLT3 MYO5B HHATL EYS ST8SIA4	1.35e-05	200	115	6	4a426ef88376d8bb2b9dc50aa06e7b9fc50ecc9c
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 FLT3 MYO5B HHATL EYS ST8SIA4	1.35e-05	200	115	6	1276bfa911fddada4235e12e3081baa53164574b
ToppCell	Children_(3_yrs)-Immune-monocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TBXAS1 FLT3 IFNGR1 DOCK5 ACSL1 ST8SIA4	1.35e-05	200	115	6	881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2--L2-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 FLT3 MYO5B HHATL EYS ST8SIA4	1.35e-05	200	115	6	c65e6336725856c4b5f6aeba1cf86a23ec815d34
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NDRG2 ACSL1 HOMER2 UNC80 RASAL1 L3MBTL4	1.35e-05	200	115	6	7c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCell	Parenchymal-10x3prime_v2-Stromal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FN1 CES1 DDR2 NDRG2 DST PLEKHH2	1.35e-05	200	115	6	f6be0f24e607abb9007823a54fb0b24d04990a89
ToppCell	Sepsis-Bac-SEP-Myeloid-cDC1\|Bac-SEP / Disease, condition lineage and cell class	FLT3 NDRG2 C1orf21 DST NAV1 FBXO27	1.35e-05	200	115	6	cd381644fd8b8674a017d267bfbb00f2668294ae
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SDK2 FN1 DDR2 NDRG2 DST PLEKHH2	1.35e-05	200	115	6	44a68bacdb3d5bf563bd35952176995850933a81
ToppCell	Caecum-T_cell-gd_T\|T_cell / Region, Cell class and subclass	DOCK5 SCCPDH C1orf21 ECI2 KIR3DL1 KIR3DL2	1.35e-05	200	115	6	564117144a3059017a07d66f718b9b5a1f18265b
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 FLT3 MYO5B HHATL EYS ST8SIA4	1.35e-05	200	115	6	fbeee1c16ac0a7fe28d90491c8b079f21ce80bdc
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 FLT3 MYO5B HHATL EYS ST8SIA4	1.35e-05	200	115	6	c6eda342ea0cb37d71d89dbb8d11e819e0745172
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SDK2 FN1 DDR2 NDRG2 DST PLEKHH2	1.35e-05	200	115	6	dc61016c61729f69649cfb21f6264e685ce83dea
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYO5B NBEA ACSL1 HOMER2 RASAL1 TMEM63A	1.35e-05	200	115	6	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 FLT3 MYO5B HHATL EYS ST8SIA4	1.35e-05	200	115	6	117a25b3b9cdbc2e198381350a8362bee25e82e7
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GAD2 FLT3 MYO5B HHATL EYS ST8SIA4	1.35e-05	200	115	6	d459e51507bf26865e6e7e04411379ec82a3edf8
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NBEA NDRG2 ACOT11 HOMER2 RASAL1 TMEM63A	1.35e-05	200	115	6	85c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-Langerhans_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FLT3 ST8SIA4 FBXO27 HOMER2 RASAL1	4.99e-05	154	115	5	617ad0929d2ac0eeb7b8d9b0cba687176e684ed0
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLT3 NDRG2 DST NAV1 FBXO27	4.99e-05	154	115	5	5967a0a33456d5930fc492a700ebb015ac050abb
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLT3 NDRG2 DST NAV1 FBXO27	5.15e-05	155	115	5	fab281db4c275d51240b122be78713c839ba5a95
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_dendritic-CD141-positive_myeloid_dendritic_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FLT3 NDRG2 UBQLN3 NAV1 FBXO27	5.30e-05	156	115	5	2474402f563e9e9f37351cfabc8c012e42a1d8c5
Disease	hypertension (implicated_via_orthology)	RAD51 TBXAS1 FN1 CYP11B2 NISCH	1.37e-04	128	113	5	DOID:10763 (implicated_via_orthology)
Disease	Autosomal Dominant Parkinsonism	ATP13A2 TH PRKN	1.67e-04	28	113	3	C0752098
Disease	Autosomal Dominant Juvenile Parkinson Disease	ATP13A2 TH PRKN	1.67e-04	28	113	3	C0752097
Disease	hepatitis C (is_implicated_in)	PDCD1 KIR3DL1 KIR3DS1	1.67e-04	28	113	3	DOID:1883 (is_implicated_in)
Disease	Parkinsonism, Experimental	ATP13A2 TH PRKN	1.67e-04	28	113	3	C0752101
Disease	Autosomal Recessive Parkinsonism	ATP13A2 TH PRKN	1.67e-04	28	113	3	C0752100
Disease	Familial Juvenile Parkinsonism	ATP13A2 TH PRKN	1.67e-04	28	113	3	C0752104
Disease	Ramsay Hunt Paralysis Syndrome	ATP13A2 TH PRKN	1.67e-04	28	113	3	C0242423
Disease	PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE	ATP13A2 TH PRKN	1.67e-04	28	113	3	C1868675
Disease	tuberculosis (is_implicated_in)	IFNGR1 KIR3DL1 KIR3DS1	1.67e-04	28	113	3	DOID:399 (is_implicated_in)
Disease	Parkinsonism, Juvenile	ATP13A2 TH PRKN	2.06e-04	30	113	3	C0752105
Disease	Parkinsonian Disorders	ATP13A2 TH PRKN	2.06e-04	30	113	3	C0242422
Disease	Parkinson's disease (is_implicated_in)	PHACTR2 ATP13A2 TH PRKN	2.12e-04	76	113	4	DOID:14330 (is_implicated_in)
Disease	stomach cancer (is_marker_for)	PDCD1 CES1 DDR2 NBEA XPO1	2.22e-04	142	113	5	DOID:10534 (is_marker_for)
Disease	fear of minor pain measurement	SLC39A4 DOCK5 PRKN	2.27e-04	31	113	3	EFO_0008340
Disease	Nerve Degeneration	ATP13A2 SIRT1 TH PRKN	2.97e-04	83	113	4	C0027746
Disease	progressive familial intrahepatic cholestasis (is_implicated_in)	SEMA7A MYO5B	3.01e-04	7	113	2	DOID:0070221 (is_implicated_in)
Disease	hepatitis B (is_implicated_in)	PDCD1 IFNGR1 KIR3DS1	3.86e-04	37	113	3	DOID:2043 (is_implicated_in)
Disease	Fanconi anemia (implicated_via_orthology)	RAD51 FANCM	4.01e-04	8	113	2	DOID:13636 (implicated_via_orthology)
Disease	hyperprolactinemia (biomarker_via_orthology)	TH HSD3B2	5.14e-04	9	113	2	DOID:12700 (biomarker_via_orthology)
Disease	hepatocellular carcinoma (is_implicated_in)	PDCD1 FLT3 XPO1 ARID2 KIR3DS1	6.76e-04	181	113	5	DOID:684 (is_implicated_in)
Disease	Diabetic Retinopathy	GAD2 SIRT1	7.82e-04	11	113	2	C0011884
Disease	interleukin-22 receptor subunit alpha-2 measurement	FLT3 IFNGR1	7.82e-04	11	113	2	EFO_0020500
Disease	Parkinson Disease, Secondary Vascular	ATP13A2 PRKN	9.36e-04	12	113	2	C0751414
Disease	Atherosclerotic Parkinsonism	ATP13A2 PRKN	9.36e-04	12	113	2	C0751415
Disease	Secondary Parkinson Disease	ATP13A2 PRKN	9.36e-04	12	113	2	C0030569
Disease	alcohol use disorder (implicated_via_orthology)	GAD2 SIRT1 ARID2 HOMER2 HOMER1	9.44e-04	195	113	5	DOID:1574 (implicated_via_orthology)
Disease	Cocaine-Related Disorders	GAD2 CES1 HOMER2 HOMER1	1.08e-03	117	113	4	C0236736
Disease	hepatocellular carcinoma (is_marker_for)	PDCD1 CES1 DDR2 BCORL1 XPO1 ARID2	1.09e-03	301	113	6	DOID:684 (is_marker_for)
Disease	colorectal cancer (is_implicated_in)	CES1 DDR2 XPO1 ARID2	1.23e-03	121	113	4	DOID:9256 (is_implicated_in)
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	NPHP3 LATS1	1.28e-03	14	113	2	DOID:898 (implicated_via_orthology)
Disease	Manganese Poisoning	ATP13A2 PRKN	1.28e-03	14	113	2	C0677050
Disease	Cocaine Abuse	GAD2 CES1 HOMER2 HOMER1	1.47e-03	127	113	4	C0009171
Disease	Dyskinesia, Medication-Induced	TH HOMER1	1.48e-03	15	113	2	C0751088
Disease	Dyskinesia, Drug-Induced	TH HOMER1	1.48e-03	15	113	2	C0013386
Disease	Inborn Errors of Metabolism	MYO5B CES1	1.90e-03	17	113	2	C0025521
Disease	susceptibility to hepatitis B infection measurement	SDK2 MYO5B ARFGEF2	1.92e-03	64	113	3	EFO_0008405
Disease	Cocaine Dependence	GAD2 CES1 HOMER2 HOMER1	2.04e-03	139	113	4	C0600427
Disease	Schizophrenia	GAD2 PDE4D HTR5A MYO5B SIRT1 STON2 NAV1 HOMER2 HOMER1 PCNT	2.12e-03	883	113	10	C0036341
Disease	osteoporosis (implicated_via_orthology)	SIRT1 IFNGR1	2.38e-03	19	113	2	DOID:11476 (implicated_via_orthology)
Disease	Major Depressive Disorder	GAD2 FREM3 TH HOMER1 PCNT	2.48e-03	243	113	5	C1269683
Disease	Prostatic Neoplasms	TBXAS1 PDE4D CYP11B2 XPO1 SIRT1 ARID2 HSD3B2 GREB1	2.59e-03	616	113	8	C0033578
Disease	Malignant neoplasm of prostate	TBXAS1 PDE4D CYP11B2 XPO1 SIRT1 ARID2 HSD3B2 GREB1	2.59e-03	616	113	8	C0376358
Disease	pentachlorophenol measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022071
Disease	parathion measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022070
Disease	potassium chromate measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022072
Disease	mercuric chloride measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022068
Disease	heptachlor epoxide measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022067
Disease	methoxychlor measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022069
Disease	4,6-dinitro-o-cresol measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022053
Disease	2,4,5-trichlorophenol measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022052
Disease	azinphos methyl measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022055
Disease	aldrin measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022054
Disease	dicofol measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022060
Disease	disulfoton measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022062
Disease	dieldrin measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022061
Disease	endrin measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022064
Disease	endosulfan measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022063
Disease	heptachlor measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022066
Disease	ethion measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022065
Disease	chlorpyrifos measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022057
Disease	cadmium chloride measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022056
Disease	diazinon measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022059
Disease	dibutyl phthalate measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0022058
Disease	environmental exposure measurement	PDE4D GSDMC EYS	2.80e-03	73	113	3	EFO_0008360
Disease	DDT metabolite measurement	PDE4D GSDMC EYS	2.91e-03	74	113	3	EFO_0007886
Disease	epilepsy (biomarker_via_orthology)	SIRT1 TH	2.91e-03	21	113	2	DOID:1826 (biomarker_via_orthology)
Disease	Headache, HbA1c measurement	DDR2 PLXND1	2.91e-03	21	113	2	EFO_0004541, HP_0002315
Disease	Parkinson's disease (implicated_via_orthology)	ATP13A2 SIRT1 TH PRKN	3.17e-03	157	113	4	DOID:14330 (implicated_via_orthology)
Disease	Parkinson disease	ATP13A2 PRKN	3.19e-03	22	113	2	cv:C0030567
Disease	malaria (is_implicated_in)	KIR3DL1 KIR3DS1	3.80e-03	24	113	2	DOID:12365 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SEHSINGRRFPVEMQ	PTPRG	161	P23470
QAERNFHTVPYMVGI	CES1	336	P23141
DVFGVTHRESIMNVN	HSD3B2	86	P26439
LSTEFAEHRVPNGMN	CCDC186	171	Q7Z3E2
MEVRFFRGQFSSVVH	BTNL8	51	Q6UX41
PLANRQQITEMFFEH	ACTRT3	111	Q9BYD9
QQITEMFFEHLGVPA	ACTRT3	116	Q9BYD9
IYMRSEPVAQVFVHG	ACSL1	576	P33121
VVTGPFHFSDIMIQK	GSDMC	76	Q9BYG8
RIFQARFPHFEITTM	BCORL1	1711	Q5H9F3
QNAGPVFRTHEMFIN	ARFGEF2	416	Q9Y6D5
VIQQAVPQSHMFGRV	ARID2	791	Q68CP9
AIEMFHFRGPSQVGD	ACOT11	266	Q8WXI4
PGVFSQHQAMERDST	ANKRD17	2491	O75179
PGMFRQVQVSFVSRI	DMXL1	516	Q9Y485
DEGAFQLPHVMQVVT	RASAL1	626	O95294
LVPMGFTTATEFHQR	RAD51	81	Q06609
VNDHIPMFTQSVYRV	PCDHGA11	236	Q9Y5H2
FHGRIFQESFIMGPV	KIR3DL2	71	P43630
NQAEFRMGPVTSAHV	LILRA2	376	Q8N149
TPGVTIMRQTNRFFF	PAN2	196	Q504Q3
FFRMVISNPAATHQD	GAD2	556	Q05329
ALGPQNRTMHFVTEF	OR11H6	16	Q8NGC7
PIMTFDRFHAQVSQV	HHATL	221	Q9HCP6
FESMFLGHIPANVQI	EYS	2281	Q5T1H1
HFVFSQPGGQLESMR	GREB1	1516	Q4ZG55
TGQTDFMIHQNVVPA	LATS1	351	O95835
FMIHQNVVPAGTVNR	LATS1	356	O95835
FQFVGIENIHVMRSS	MTMR6	266	Q9Y217
ARFVRFIPVTDHSMN	DDR2	161	Q16832
QGIGHFQNTIREMFS	DST	5171	Q03001
RFRSQILQHFGSMPE	LONRF1	701	Q17RB8
MGEQPIFTTRAHVFQ	HOMER2	1	Q9NSB8
MTGAQTRFTFELPNH	KIAA1109	3011	Q2LD37
LSQHQPIIRVMTFVG	FANCM	496	Q8IYD8
FHGRIFQESFNMSPV	KIR3DL1	71	P43629
RVTQLPNGRDFHMSV	PDCD1	96	Q15116
TITVAGERFHMVQNV	PLXND1	1086	Q9Y4D7
GNRPLTVIMHTIFQE	PDE4D	416	Q08499
SFPEHENGFQIGMRL	L3MBTL4	76	Q8NA19
TFPNVREMFNSHRLG	FOXC2	446	Q99958
VHHQAQRFRFSPMGV	ELAVL1	211	Q15717
VTVNFENSNGHMIPI	PHACTR2	91	O75167
ELATVQPGQNFHMFT	PSMA5	216	P28066
HVQDQPLGMAFVTFQ	TMEM63A	341	O94886
QRGMFTVSDHTPEQR	PCNT	181	O95613
MGEQPIFSTRAHVFQ	HOMER1	1	Q86YM7
VRMIDFAHVFPSNTI	IPMK	381	Q8NFU5
FSIPVHFMNGIYQVV	PLEKHH2	1121	Q8IVE3
RQMETGLSPEIVHFN	MAN1B1	561	Q9UKM7
VPTIDIHMNQIGFER	PLOD1	596	Q02809
SFDEMLPGTHFQRVI	OGDH	871	Q02218
PHFDLQNRGVVSMVI	FLT3	116	P36888
DPFVMHEVGVVAFQN	CDC16	401	Q13042
HRFPFSSALQRMSVV	ATP13A2	626	Q9NQ11
EGSQHPFGAMNIVRT	HIKESHI	91	Q53FT3
IGMNRQSPHIGSFVA	DOCK5	941	Q9H7D0
SVGQQMIFEEHGFRR	FN1	2136	P02751
SQTAFHMQVRPGGLV	FSCN3	211	Q9NQT6
GNHPTFEDMQVLVSR	BMPR2	441	Q13873
PRANMHISESQQEFF	C1orf21	86	Q9H246
IRVNVVAPGFVHTDM	CBR4	171	Q8N4T8
MGFQRRFFHQDQSPV	COQ8A	156	Q8NI60
VMVRNEITGHTYRFP	DENND5B	1011	Q6ZUT9
QMVFTVRHATVTFQP	HTR5A	256	P47898
TQQAAFHQIAMEPFE	MARCO	16	Q9UEW3
QLPFGSQTRMFLHEV	INPP5B	111	P32019
LEMHQTFQELGPIFR	CYP11B2	66	P19099
VTSFPVVQLHMNRTA	ECI2	21	O75521
FENPTMVQFDHRILG	COX15	316	Q7KZN9
NGSEQTVVAFFIMPA	GYS1	356	P13807
MGVRFVSFEHRGQDT	FBXO27	246	Q8NI29
NYVLVPTMFQHGRTS	CAPN6	466	Q9Y6Q1
TMVTARPNFQDSIHV	SDK2	841	Q58EX2
RPISSIGQVQSYMEH	SPACA9	41	Q96E40
TQVGPDHNRSFIAEM	DHX9	201	Q08211
IMIDIFHPSVFVNGD	IFNGR1	141	P15260
REVTEGIVSTFNMHQ	NAV1	1581	Q8NEY1
LDFAPGVRMQTFQVT	FREM3	2071	P0C091
ARHEAPVFVVTSNGM	FUT1	251	P19526
MIVFVRFNSSHGFPV	PRKN	1	O60260
MATEQRPFHLVVFGA	SCCPDH	1	Q8NBX0
IIQNFVRVHVDAPGM	NDRG2	91	Q9UN36
MIQLQQSFRGPEFAH	NPHP3	246	Q7Z494
PMQFHSFDRSVVVPV	NBEA	1781	Q8NFP9
FHGRIFQEGFNMSPV	KIR3DS1	71	Q14943
MFATINRQETPRFHA	SMG1	2176	Q96Q15
VDFVFQQHSSEVPMT	SLC39A4	206	Q6P5W5
DFITMNPSVVQRAFG	ST8SIA4	186	Q92187
TFVQQHLMIGTDPRT	SIRT1	186	Q96EB6
QLAAMLPSVVQHFGF	NDRG4	91	Q9ULP0
NMHEVFSQLAPFEVR	INTS5	926	Q6P9B9
RFANHVNVEFSMPTT	STON2	826	Q8WXE9
GRVFHFPEQEGQMVE	PNMA6A	106	P0CW24
MNVHNLAIVFGPTLF	ARAP1	1101	Q96P48
VPGSVANQVFHPVMF	NCAPD3	126	P42695
HISMENFRTPNFGLV	CLUAP1	21	Q96AJ1
RHSASPMGVQDFDIV	TBXAS1	286	P24557
RRHFVQVQVGEVMPF	XPO1	596	O14980
FRMNQAPTVGFEADV	ST6GALNAC4	101	Q9H4F1
QQAFPMHREIAVDFG	TRMO	241	Q9BU70
HVISPFTNQERREGM	UNC80	2696	Q8N2C7
ITQDREQLMFPFHFV	MRPS9	306	P82933
VGFQPIRTSEHMAAA	STT3B	311	Q8TCJ2
DQHFRLTGSTPMQVV	NISCH	1241	Q9Y2I1
FFHLDPANVVMFEQR	UAP1L1	186	Q3KQV9
QIFPMEERIFNFHTD	ZNF470	191	Q6ECI4
PMTFITNSNGEVDHR	ZNF281	846	Q9Y2X9
HPETQQTFIRLEGSM	TMCO6	96	Q96DC7
EHSFAFNIMEIQPFR	SEMA7A	446	O75326
LTVSSVHFMNFDRPN	PKHD1L1	2736	Q86WI1
ERMLFHGSPFVNAII	TNKS2	1026	Q9H2K2
SLMRQHVSVPEFVTQ	UBQLN3	156	Q9H347
MVQQHLSEPVATFFQ	WDR81	1416	Q562E7
MPQVTFNDVAIDFTH	ZNF181	1	Q2M3W8
HVPMLADRTFAQFSQ	TH	366	P07101
LPMFESNFVQVTHQG	GARIN5B	41	Q8N5Q1
VEYMAPEVVNRQGHS	RPS6KA1	226	Q15418
PRMSNTAFIIVHFAD	MYO5B	541	Q9ULV0