Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphatidylcholine transfer activity	PITPNA PITPNB	1.03e-04	6	53	2	GO:0120019
GeneOntologyMolecularFunction	phosphatidylinositol transfer activity	PITPNA PITPNB	3.74e-04	11	53	2	GO:0008526
GeneOntologyMolecularFunction	transition metal ion binding	APIP ZFHX4 APOBEC3H ZFHX2 CUL9 CP ZFHX3 PTCH1 MPPE1 GALNT4	1.01e-03	1189	53	10	GO:0046914
GeneOntologyMolecularFunction	polypeptide N-acetylgalactosaminyltransferase activity	GALNT17 GALNT4	1.27e-03	20	53	2	GO:0004653
GeneOntologyMolecularFunction	phosphatidylcholine transporter activity	PITPNA PITPNB	1.27e-03	20	53	2	GO:0008525
GeneOntologyMolecularFunction	protein kinase A regulatory subunit binding	C2orf88 RYR2	1.99e-03	25	53	2	GO:0034237
GeneOntologyMolecularFunction	phospholipid transfer activity	PITPNA PITPNB	2.16e-03	26	53	2	GO:0120014
Domain	ZnF_U1	ZFHX4 ZFHX2 ZFHX3	7.07e-05	29	52	3	SM00451
Domain	Znf_U1	ZFHX4 ZFHX2 ZFHX3	7.07e-05	29	52	3	IPR003604
Domain	IP_trans	PITPNA PITPNB	7.56e-05	5	52	2	PF02121
Domain	PI_transfer	PITPNA PITPNB	1.13e-04	6	52	2	IPR001666
Domain	DH_1	ABR KALRN SOS2	7.18e-04	63	52	3	PS00741
Domain	RhoGEF	ABR KALRN SOS2	8.98e-04	68	52	3	SM00325
Domain	RhoGEF	ABR KALRN SOS2	9.77e-04	70	52	3	PF00621
Domain	DH_2	ABR KALRN SOS2	9.77e-04	70	52	3	PS50010
Domain	DH-domain	ABR KALRN SOS2	1.02e-03	71	52	3	IPR000219
Domain	-	ABR KALRN SOS2	1.02e-03	71	52	3	1.20.900.10
Domain	-	PITPNA PITPNB	1.85e-03	23	52	2	3.30.530.20
Domain	START-like_dom	PITPNA PITPNB	1.85e-03	23	52	2	IPR023393
Domain	Ricin_B_lectin	GALNT17 GALNT4	2.19e-03	25	52	2	PF00652
Domain	RICIN	GALNT17 GALNT4	2.74e-03	28	52	2	SM00458
Domain	RICIN_B_LECTIN	GALNT17 GALNT4	2.74e-03	28	52	2	PS50231
Domain	Ricin_B_lectin	GALNT17 GALNT4	3.15e-03	30	52	2	IPR000772
Domain	Glycos_transf_2	GALNT17 GALNT4	3.15e-03	30	52	2	PF00535
Domain	Glyco_trans_2-like	GALNT17 GALNT4	3.15e-03	30	52	2	IPR001173
Domain	GDS_CDC24_CS	ABR SOS2	5.27e-03	39	52	2	IPR001331
Pubmed	Behavioral abnormalities observed in Zfhx2-deficient mice.	ZFHX4 ZFHX2 ZFHX3	1.34e-08	4	53	3	23300874
Pubmed	Cloning and expression of human cDNA encoding phosphatidylinositol transfer protein beta.	PITPNA PITPNB	2.28e-06	2	53	2	8541325
Pubmed	Phospholipid transfer proteins.	PITPNA PITPNB	2.28e-06	2	53	2	1883207
Pubmed	The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers.	ZFHX4 ZFHX3	2.28e-06	2	53	2	10873665
Pubmed	Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells.	PITPNA PITPNB	2.28e-06	2	53	2	18636990
Pubmed	Biochemical and biological functions of class I phosphatidylinositol transfer proteins.	PITPNA PITPNB	2.28e-06	2	53	2	17490911
Pubmed	Specific and nonspecific membrane-binding determinants cooperate in targeting phosphatidylinositol transfer protein beta-isoform to the mammalian trans-Golgi network.	PITPNA PITPNB	2.28e-06	2	53	2	16540520
Pubmed	Biological functions of phosphatidylinositol transfer proteins.	PITPNA PITPNB	2.28e-06	2	53	2	15052341
Pubmed	Structure of PITPbeta in complex with phosphatidylcholine: comparison of structure and lipid transfer to other PITP isoforms.	PITPNA PITPNB	2.28e-06	2	53	2	16274224
Pubmed	Genetic ablation of phosphatidylinositol transfer protein function in murine embryonic stem cells.	PITPNA PITPNB	2.28e-06	2	53	2	11907258
Pubmed	An isoform of the phosphatidylinositol-transfer protein transfers sphingomyelin and is associated with the Golgi system.	PITPNA PITPNB	2.28e-06	2	53	2	7654206
Pubmed	The anti-apoptotic activity associated with phosphatidylinositol transfer protein alpha activates the MAPK and Akt/PKB pathway.	PITPNA PITPNB	6.83e-06	3	53	2	18501717
Pubmed	Phosphatidylinositol transfer proteins regulate megakaryocyte TGF-β1 secretion and hematopoiesis in mice.	PITPNA PITPNB	6.83e-06	3	53	2	30042096
Pubmed	Cloning and characterization of a novel human phosphatidylinositol transfer protein, rdgBbeta.	PITPNA PITPNB	1.36e-05	4	53	2	10531358
Pubmed	Phosphatidylinositol transfer protein, cytoplasmic 1 (PITPNC1) binds and transfers phosphatidic acid.	PITPNA PITPNB	1.36e-05	4	53	2	22822086
Pubmed	Structure of a multifunctional protein. Mammalian phosphatidylinositol transfer protein complexed with phosphatidylcholine.	PITPNA PITPNB	1.36e-05	4	53	2	11104777
Pubmed	Identification of a Golgi GPI-N-acetylgalactosamine transferase with tandem transmembrane regions in the catalytic domain.	MPPE1 GALNT4	2.27e-05	5	53	2	29374258
Pubmed	Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.	ABR KALRN SOS2	2.71e-05	38	53	3	11756498
Pubmed	FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration.	CCDC198 NEB NUP205	3.68e-05	42	53	3	29348145
Pubmed	NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.	ABR KALRN SOS2	3.95e-05	43	53	3	12376548
Pubmed	Arrhythmogenic Right Ventricular Cardiomyopathy Overview	TGFB3 RYR2	1.02e-04	10	53	2	20301310
Pubmed	Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR).	ABR KALRN SOS2	1.08e-04	60	53	3	12787561
Pubmed	PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function.	PIK3C2A PTCH1	1.24e-04	11	53	2	24697898
Pubmed	Gli3-deficient mice exhibit cleft palate associated with abnormal tongue development.	TGFB3 PTCH1	1.76e-04	13	53	2	18816854
Pubmed	Stomach regional specification requires Hoxa5-driven mesenchymal-epithelial signaling.	TGFB3 PTCH1	2.05e-04	14	53	2	12163410
Pubmed	Phosphatidylinositol transfer protein/planar cell polarity axis regulates neocortical morphogenesis by supporting interkinetic nuclear migration.	PITPNA PITPNB	2.05e-04	14	53	2	35649377
Pubmed	The Mn1 transcription factor acts upstream of Tbx22 and preferentially regulates posterior palate growth in mice.	TGFB3 PTCH1	2.05e-04	14	53	2	18948418
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HIVEP3 USP34 ABR KALRN INTS11 CUL9 PTCH1 SPPL2B	2.52e-04	1105	53	8	35748872
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	USP34 ZFHX4 ACTR5 SGPL1 NTAQ1 INTS11 CUL9 ZFHX3	2.70e-04	1116	53	8	31753913
Pubmed	Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling.	CACNA1B ZFHX3	2.70e-04	16	53	2	17444492
Pubmed	Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus.	TGFB3 PTCH1	3.43e-04	18	53	2	19570847
Pubmed	Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3.	ABR PITPNA	3.83e-04	19	53	2	12621583
Pubmed	The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development.	ZFHX4 ZFHX3	4.25e-04	20	53	2	35177643
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	TGFB3 ZFHX4 ZFHX2 PTCH1	5.88e-04	251	53	4	29031500
Pubmed	Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding.	GALNT17 GALNT4	6.16e-04	24	53	2	31740596
Pubmed	Loss of the disease-associated glycosyltransferase Galnt3 alters Muc10 glycosylation and the composition of the oral microbiome.	GALNT17 GALNT4	6.16e-04	24	53	2	31882545
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	USP34 RBM22 PIK3C2A PITPNB NUP205	6.55e-04	457	53	5	32344865
Pubmed	A Golgi Lipid Signaling Pathway Controls Apical Golgi Distribution and Cell Polarity during Neurogenesis.	PITPNA PITPNB	6.68e-04	25	53	2	29587143
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	CACNA1B KALRN SGPL1 LRRC8A IDH2	7.79e-04	475	53	5	31040226
Pubmed	Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome.	NEB RYR2	7.80e-04	27	53	2	18468998
Pubmed	Temporospatial sonic hedgehog signalling is essential for neural crest-dependent patterning of the intrinsic tongue musculature.	TGFB3 PTCH1	8.40e-04	28	53	2	31719045
Pubmed	An Integrative Synthetic Biology Approach to Interrogating Cellular Ubiquitin and Ufm Signaling.	HINFP UFC1	8.40e-04	28	53	2	32545848
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	USP34 ZFHX4 INTS11 CUL9	9.07e-04	282	53	4	23667531
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	CACNA1B PTCD1 C2orf88 CUL9 NUP205	9.44e-04	496	53	5	31343991
Pubmed	Galnt1 is required for normal heart valve development and cardiac function.	GALNT17 GALNT4	1.39e-03	36	53	2	25615642
Pubmed	A global genomic transcriptional code associated with CNS-expressed genes.	GALNT17 ZFHX4 ZFHX3 PTCH1	1.41e-03	318	53	4	16919269
Cytoband	Ensembl 112 genes in cytogenetic band chr17p13	ZMYND15 CYB5D2 ABR PITPNA	6.94e-04	346	53	4	chr17p13
Cytoband	17p13.2	ZMYND15 CYB5D2	1.87e-03	55	53	2	17p13.2
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZFHX4 ZFHX2 ZFHX3	2.72e-06	15	34	3	529
GeneFamily	Phosphatidylinositol transfer proteins	PITPNA PITPNB	5.12e-05	6	34	2	1151
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ABR KALRN SOS2	2.56e-04	66	34	3	722
GeneFamily	Polypeptide N-acetylgalactosaminyltransferases	GALNT17 GALNT4	6.38e-04	20	34	2	433
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	HINFP HIVEP3 ZNF674 ZFHX2 ZFHX3	1.04e-02	718	34	5	28
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Myeloid-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP3 CCDC198 GPR65 FRMD3	3.31e-05	153	53	4	e426db29e4ba83e7930dc88c74fc975b177c9540
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Myeloid\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP3 CCDC198 GPR65 FRMD3	3.31e-05	153	53	4	668eacd76aad6054bd7d57e3af0b122c2443465f
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Myeloid-macrophage\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP3 CCDC198 GPR65 FRMD3	3.31e-05	153	53	4	4b999892fb797e9f0d391630094f466463299d57
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CACNA1B ZFHX3 PTCH1 ADAMTSL2	3.66e-05	157	53	4	b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN ZFHX2 CUL9 NEB	3.84e-05	159	53	4	7619d0d49738dd08daf01b42664691a5323aa793
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN ZFHX2 CUL9 NEB	3.84e-05	159	53	4	4000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CACNA1B PTCH1 ADAMTSL2 TMEM117	4.99e-05	170	53	4	fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIVEP3 GALNT17 RYR2 FRMD3	6.23e-05	180	53	4	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	GALNT17 KALRN ZFHX3 RYR2	6.23e-05	180	53	4	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 KALRN NEB RYR2	6.78e-05	184	53	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 KALRN NEB RYR2	6.78e-05	184	53	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 KALRN NEB RYR2	6.78e-05	184	53	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	megakaryocytic\|World / Lineage and Cell class	KALRN C2orf88 RYR2 FRMD3	6.78e-05	184	53	4	b1c630ca2189d9d49402a5621b57618976fbea5c
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TGFB3 GALNT17 ZFHX3 RYR2	6.92e-05	185	53	4	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-double_negative_T_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP3 GPR65 ADAMTSL2 FRMD3	7.07e-05	186	53	4	11929e36d8c9b4c4bc2f5e912f139f474f91ab00
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TGFB3 CP PTCH1 PM20D2	7.07e-05	186	53	4	827f2f2ddde315d1e5970dd56f906c555ec699af
ToppCell	megakaryocytic-Megakaryocyte\|World / Lineage and Cell class	KALRN C2orf88 IDH2 RYR2	7.07e-05	186	53	4	acd15a169b6122b28cc99ef34de10701edcfedfe
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ZFHX4 KALRN CP ADAMTSL2	7.22e-05	187	53	4	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GALNT17 PTCH1 RYR2 FRMD3	7.52e-05	189	53	4	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CACNA1B ZFHX3 PTCH1 ADAMTSL2	7.52e-05	189	53	4	0abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CACNA1B C2orf88 PTCH1 ADAMTSL2	7.68e-05	190	53	4	d24af6af3271e34afab744352afd28be8a7cc5c3
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIVEP3 GALNT17 RYR2 FRMD3	7.68e-05	190	53	4	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	APIP HIVEP3 CP ADAMTSL2	7.83e-05	191	53	4	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABR LRRC8A CP FRMD3	7.99e-05	192	53	4	3259cb89d6bcf0a3c6ff1f64d85e8a1f54124e91
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZFHX4 KALRN CP ADAMTSL2	8.15e-05	193	53	4	5b602b1702283184bd3943c2a6f2290b7c37e407
ToppCell	tumor_Lung-T/NK_cells-Exhausted_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	GPR65 SRGAP3 APOBEC3H IDH2	8.15e-05	193	53	4	3655b7d5ee055c0067764a70e4a0b4724e7a4e85
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZFHX4 KALRN CP ADAMTSL2	8.15e-05	193	53	4	c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HIVEP3 GALNT17 RYR2 ADAMTSL2	8.15e-05	193	53	4	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HIVEP3 GALNT17 RYR2 ADAMTSL2	8.15e-05	193	53	4	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GALNT17 PTCH1 RYR2 ADAMTSL2	8.32e-05	194	53	4	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HIVEP3 GALNT17 RYR2 ADAMTSL2	8.32e-05	194	53	4	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZFHX4 KALRN PTCH1 ADAMTSL2	8.32e-05	194	53	4	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ZFHX4 KALRN SRGAP3 PTCH1	8.32e-05	194	53	4	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ZFHX4 KALRN SRGAP3 PTCH1	8.49e-05	195	53	4	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B GALNT17 KALRN RYR2	8.65e-05	196	53	4	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ZFHX4 KALRN SRGAP3 ZFHX3	8.65e-05	196	53	4	b04ca69b0ed44e09c989b575f747e1e819cd8008
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ZFHX4 KALRN SRGAP3 ZFHX3	8.65e-05	196	53	4	a31e227de2dc077b81881295b012d22fedbd65ed
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZFHX4 KALRN PTCH1 ADAMTSL2	8.83e-05	197	53	4	ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZFHX4 KALRN PTCH1 ADAMTSL2	8.83e-05	197	53	4	37f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B GALNT17 KALRN RYR2	9.00e-05	198	53	4	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B GALNT17 KALRN RYR2	9.00e-05	198	53	4	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B GALNT17 KALRN RYR2	9.00e-05	198	53	4	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B GALNT17 KALRN RYR2	9.00e-05	198	53	4	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1B GALNT17 KALRN RYR2	9.00e-05	198	53	4	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	HIVEP3 GALNT17 RYR2 FRMD3	9.18e-05	199	53	4	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	CACNA1B GALNT17 KALRN RYR2	9.36e-05	200	53	4	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_3\|Control_saline / Treatment groups by lineage, cell group, cell type	TGFB3 ABR ZFHX3 RYR2	9.36e-05	200	53	4	b0866b497aa71d06cef25f9a335fa584e95fa7e0
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TGFB3 ABR ZFHX3 RYR2	9.36e-05	200	53	4	c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCell	LPS_only-Mesenchymal_myocytic\|LPS_only / Treatment groups by lineage, cell group, cell type	TGFB3 ZFHX3 PTCH1 RYR2	9.36e-05	200	53	4	8bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Serous\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	HINFP ABR FRMD3 TMEM117	9.36e-05	200	53	4	61bae10c8b12196d9cee766897971b81cb897191
Disease	arrhythmogenic right ventricular cardiomyopathy (is_implicated_in)	TGFB3 RYR2	1.31e-04	10	51	2	DOID:0050431 (is_implicated_in)
Disease	Dyschondroplasias	IDH2 ADAMTSL2	4.92e-04	19	51	2	C0013366
Disease	Hydrops Fetalis	SGPL1 SOS2	4.92e-04	19	51	2	C0020305
Disease	obesity (implicated_via_orthology)	ZFHX4 SGPL1 ZFHX2 ZFHX3	5.24e-04	215	51	4	DOID:9970 (implicated_via_orthology)
Disease	lung squamous cell carcinoma (is_implicated_in)	IDH2 PTCH1	7.89e-04	24	51	2	DOID:3907 (is_implicated_in)
Disease	hearing threshold measurement	GALNT17 ACTR5	1.08e-03	28	51	2	EFO_0007618

Protein segments in the cluster

Peptide	Gene	Start	Entry
HQQYDCKWYIPLADL	ABR	341	Q12979
SEINKYKLYPWIHQF	CARNMT1	246	Q8N4J0
IFASRLYYHWCKPQQ	APOBEC3H	106	Q6NTF7
HKWRCPDYYENNVHK	ACTR5	261	Q9H9F9
AKCLIWKYQLYLHGL	DSCR4	86	P56555
AQPRQWKKYDFHYDN	CACNA1B	1336	Q00975
YYKRNRPHICSFWVK	RBM22	156	Q9NW64
LNIHEKAWNAYPYCR	PITPNA	81	Q00169
KKNPFHLELALEYWC	NUP205	451	Q92621
LTCLKLWYNHIAYIP	LRRC8A	641	Q8IWT6
FLCSTPAWAKEKHYY	CP	11	P00450
NHYYKLFIPWTNQKI	INTS11	276	Q5TA45
IYYLAIFQCNWPEVK	MPPE1	41	Q53F39
WEKRYYCFKHPNCLP	PIK3C2A	896	O00443
HERKLHIYVWYCQNK	KALRN	2011	O60229
LAIKVNLCGHWYYSK	ADAMTSL2	926	Q86TH1
LVFHEKAWNAYPYCR	PITPNB	81	P48739
HLWKCGVENQAFYKY	FRMD3	296	A2A2Y4
FAHSCFQYAIQKKWP	IDH2	231	P48735
CKSFDWYLKNVFPNL	GALNT4	421	Q8N4A0
LKCKNFQWYLDHVYP	GALNT17	441	Q6IS24
LKSWKPNHKDYYNCS	CUL9	2266	Q8IWT3
VYFHCYHTKLKQWGL	HINFP	86	Q9BQA5
FLKHQAVNNYCPWKI	CCDC198	226	Q9NVL8
PLKLLTNHYERCWKY	RYR2	2606	Q92736
NIWKLCEYIKNHDQY	NTAQ1	31	Q96HA8
IKCPIWYNILLSYNH	LRRC19	291	Q9H756
YLIPELCKQFYHLGW	APIP	26	Q96GX9
YHCWHYFELLKQLKA	SOS2	346	Q07890
YMYNRQWKLEHLCYK	PTCH1	191	Q13635
PICRWNLKHKYNYDD	MRPS18A	71	Q9NVS2
WLKKHCPHNYLVYVE	SAMD10	126	Q9BYL1
LHNWLSFYEKNYVCV	CYB5D2	116	Q8WUJ1
CYKHWQFELLNYTPA	MTRF1	216	O75570
AHDYYNVLPNKSLWK	PM20D2	311	Q8IYS1
AKNYVNGHCTKYEPW	SGPL1	26	O95470
WHFDFKNYRCTPFKY	WFDC8	111	Q8IUA0
FGKCWYIHDLLKYEF	UFC1	66	Q9Y3C8
CPKCNWHYKYQQTLE	ZFHX4	646	Q86UP3
PKCNWHYKYQQTLDV	ZFHX2	456	Q9C0A1
FKKDQYLLSPVNCWY	SRGAP3	86	O43295
GKDYCILYNPQWAHL	SPPL2B	41	Q8TCT7
WCYLNYIKPNHIQHA	HIVEP3	1606	Q5T1R4
NFTLCYDKYPLEKWQ	GPR65	166	Q8IYL9
QWACNNIKYHDIPYI	C2orf88	76	Q9BSF0
LNMWKNQIFYKPHEY	TMEM117	316	Q9H0C3
DIVNPHAYKNNKWYL	USP34	2171	Q70CQ2
AYWKVCLHYNLHKAQ	ZNF674	176	Q2M3X9
PYWYFLQCKHLIKEG	PTCD1	136	O75127
WYCNAFIFHLVYKPA	ZMYND15	686	Q9H091
KWVHEPKGYYANFCS	TGFB3	331	P10600
LKCPKCNWHYKYQQT	ZFHX3	671	Q15911
DVDYKNYLHQWTCLP	NEB	2621	P20929