Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-activated inward rectifier potassium channel activity

ABCC9 KCNJ10

2.83e-056282GO:0015272
GeneOntologyMolecularFunctionprotein antigen binding

SIRPA EP300

2.25e-0416282GO:1990405
GeneOntologyMolecularFunctionprotein binding involved in heterotypic cell-cell adhesion

SIRPA DSP

2.86e-0418282GO:0086080
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

ELOVL4 PORCN MBOAT2 EP300

3.22e-04238284GO:0016747
GeneOntologyMolecularFunctioninward rectifier potassium channel activity

ABCC9 KCNJ10

7.01e-0428282GO:0005242
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

ABCC9 CHRNA3 KCNJ10

9.72e-04140283GO:0099094
GeneOntologyMolecularFunctionmonoatomic cation channel activity

ABCC9 CHRNA3 UNC80 KCNJ10

1.26e-03343284GO:0005261
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

ABCC9 CHRNA3 KCNJ10

2.44e-03193283GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

ABCC9 CHRNA3 KCNJ10

2.58e-03197283GO:0022834
GeneOntologyMolecularFunctionO-acyltransferase activity

PORCN MBOAT2

3.09e-0359282GO:0008374
GeneOntologyMolecularFunctioncell-cell adhesion mediator activity

SIRPA DSP

3.30e-0361282GO:0098632
GeneOntologyMolecularFunctionmonoatomic ion channel activity

ABCC9 CHRNA3 UNC80 KCNJ10

3.64e-03459284GO:0005216
GeneOntologyMolecularFunctionacyltransferase activity

ELOVL4 PORCN MBOAT2 EP300 RNF133

4.06e-03775285GO:0016746
GeneOntologyMolecularFunctioncell adhesion mediator activity

SIRPA DSP

5.07e-0376282GO:0098631
GeneOntologyMolecularFunctionchannel activity

ABCC9 CHRNA3 UNC80 KCNJ10

5.86e-03525284GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

ABCC9 CHRNA3 UNC80 KCNJ10

5.90e-03526284GO:0022803
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

ABCC9 KCNJ10

8.96e-03102282GO:0005249
GeneOntologyCellularComponentmonoatomic ion channel complex

PORCN ABCC9 CHRNA3 UNC80 KCNJ10

1.31e-04378285GO:0034702
GeneOntologyCellularComponenttransmembrane transporter complex

PORCN ABCC9 CHRNA3 UNC80 KCNJ10

5.87e-04523285GO:1902495
GeneOntologyCellularComponenttransporter complex

PORCN ABCC9 CHRNA3 UNC80 KCNJ10

7.37e-04550285GO:1990351
GeneOntologyCellularComponentendoplasmic reticulum membrane

ELOVL4 PORCN NOX4 EMC1 MBOAT2 VPS13C RNF133

1.28e-031293287GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

ELOVL4 PORCN NOX4 EMC1 MBOAT2 VPS13C RNF133

1.31e-031299287GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

ELOVL4 PORCN NOX4 EMC1 MBOAT2 VPS13C RNF133

1.49e-031327287GO:0042175
GeneOntologyCellularComponentficolin-1-rich granule

SIRPA DSP FGL2

1.90e-03185283GO:0101002
GeneOntologyCellularComponentsecretory granule

ABCC9 SIRPA DSP VPS13C DYNC1H1 FGL2

1.93e-031014286GO:0030141
MousePhenoabnormal channel response

ABCC9 CHRNA3 UNC80

2.66e-0533253MP:0003484
DomainMBOAT_fam

PORCN MBOAT2

1.18e-0411282IPR004299
DomainMBOAT

PORCN MBOAT2

1.18e-0411282PF03062
DomainTBC

TBC1D2 TBC1D2B

2.44e-0349282SM00164
DomainRabGAP-TBC

TBC1D2 TBC1D2B

2.85e-0353282PF00566
DomainQuinoprotein_ADH-like_supfam

EMC1 CFAP57

2.85e-0353282IPR011047
DomainTBC_RABGAP

TBC1D2 TBC1D2B

3.06e-0355282PS50086
DomainRab-GTPase-TBC_dom

TBC1D2 TBC1D2B

3.06e-0355282IPR000195
DomainPrefoldin

CFAP57 DSP

5.19e-0372282IPR009053
DomainIg_E-set

NXPE1 KCNJ10

1.06e-02104282IPR014756
DomainAAA+_ATPase

ABCC9 DYNC1H1

1.96e-02144282IPR003593
DomainAAA

ABCC9 DYNC1H1

1.96e-02144282SM00382
Domain-

FRMD4B TBC1D2 TBC1D2B

2.02e-023912832.30.29.30
Pubmed

Brd4-p300 inhibition downregulates Nox4 and accelerates lung fibrosis resolution in aged mice.

NOX4 EP300

1.87e-06328232544088
Pubmed

Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.

ABCC9 EP300

4.10e-051228212189208
Pubmed

A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.

EMC1 MBOAT2 VPS13C

4.42e-058528323055939
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

SACS EP300 DYNC1H1 TBC1D2

1.39e-0433228437433992
Pubmed

Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers.

TBC1D2 TBC1D2B

2.17e-042728222354992
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CFAP57 DSP VPS13C DYNC1H1 TBC1D2

2.75e-0473628529676528
Pubmed

A complex oscillating network of signaling genes underlies the mouse segmentation clock.

DSP MBOAT2

4.09e-043728217095659
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

DSP TBC1D2 TBC1D2B

4.33e-0418428332908313
Pubmed

Functional dissection of Rab GTPases involved in primary cilium formation.

TBC1D2 TBC1D2B

5.53e-044328217646400
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

DSP RRP12 CENPI

6.36e-0421028316565220
CytobandEnsembl 112 genes in cytogenetic band chr15q22

GCNT3 VPS13C

2.95e-03132282chr15q22
CytobandEnsembl 112 genes in cytogenetic band chr15q25

CHRNA3 TBC1D2B

4.30e-03160282chr15q25
CoexpressionYANG_BCL3_TARGETS_UP

ABCC9 MBOAT2 VPS13C CENPI FGL2

2.48e-05333285M2424
CoexpressionGSE14308_TH17_VS_NAIVE_CD4_TCELL_DN

NOX4 EMC1 LGI2 DYNC1H1

5.72e-05199284M3384
CoexpressionGSE21033_CTRL_VS_POLYIC_STIM_DC_6H_UP

PORCN SIRPA SACS FRMD4B

5.72e-05199284M7712
CoexpressionBOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP

NOX4 EMC1 DSP FRMD4B FGL2

8.09e-05427285M17923
ToppCelldroplet-Spleen-SPLEEN-30m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC9 SIRPA FRMD4B KCNJ10

4.50e-061782846c1b5087581ca8cea976d89ea6f34088c8fc3668
ToppCelldroplet-Liver-HEPATOCYTES-1m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIRPA KCNJ10 TBC1D2B

1.21e-0415428366c93733116e31b65dfb4b0b00de5c39d19cdb84
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SIRPA FGL2 TBC1D2

1.31e-041582831635a85fc73c544028418087f36d28957dd4f458
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SIRPA FGL2 TBC1D2

1.31e-0415828380841dadfa53bcde36a3e486408a095f78e772eb
ToppCelldroplet-Liver-HEPATOCYTES-1m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMD4B KCNJ10 TBC1D2B

1.35e-04160283a494001b1f6dec33624f98fa3c24bad6988d0425
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LGI2 UNC80 TBC1D2B

1.51e-0416628365dafed953b01a9830b54309af75c7a561e88336
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LGI2 UNC80 FGL2

1.56e-04168283e40a3f85be7e9bb23bfbc1f9cb5e5fc54bb43863
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LGI2 UNC80 FGL2

1.56e-04168283b1d6c35a5ae69c8638afd68c2be5bc9ce6fd2659
ToppCell3'_v3-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

LGI2 FRMD4B FGL2

1.59e-04169283241644823e6f949aaf4c671d4579721d7ef6b0e5
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCNT3 KCNJ10 TBC1D2B

1.62e-04170283a121e10099faaeb60251eec162f38caf7c4238c2
ToppCelldroplet-Spleen-nan-24m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIRPA FRMD4B KCNJ10

1.65e-0417128335acc5c3e36bc605603c0d45375f2cf3c3e9d4cd
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GCNT3 DSP TBC1D2

1.71e-0417328381c36b9fe02c59099f080b2db02f4eaf2783911f
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-5|TCGA-Pancreas / Sample_Type by Project: Shred V9

PORCN MBOAT2 TBC1D2

1.73e-0417428373e1ad4007d94fca25ed7c6fbe5d205d4e1b8a3b
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCC9 LGI2 MBOAT2

1.73e-04174283eb8012823b08729b462d1e5212f4873bb6b4eb1e
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCC9 LGI2 MBOAT2

1.73e-0417428332fdeeebeeeca657eac6329caad4c28ca54e4d1c
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCNT3 KCNJ10 TBC1D2B

1.76e-04175283f7cd2ef79d91d64976fcdb5f1e7343b24ba27456
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

MBOAT2 DYNC1H1 KCNJ10

1.82e-04177283e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SIRPA FRMD4B FGL2

1.92e-041802837af90f0e7ca001bf1fe5c860ee54c4cc8eb483bf
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ABCC9 LGI2 FGL2

1.92e-041802839adebde5f4ca6dcb90e9113622862e14298465ac
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ABCC9 LGI2 FGL2

1.98e-04182283e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ELOVL4 NOX4 CHRNA3

1.98e-04182283e6968e0bd9cef92052d04ac54e2dd746b37623f6
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SIRPA RRP12 FGL2

2.01e-04183283fcb0f755382d88fb207fc2322cd224c09c6e2ea6
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SIRPA RRP12 FGL2

2.01e-041832834763df29c888d47c22076803b054f06b4cc29368
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DSP MBOAT2 CENPI

2.04e-041842839365cdc52a2419e3f27e1c1c9310fa707d1e506b
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DSP MBOAT2 CENPI

2.04e-04184283204d16c48f822c98dc4118ac97a4f99f7e1163c8
ToppCelldroplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP MBOAT2 CENPI

2.04e-041842837cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCelldroplet-Lung-nan-21m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP MBOAT2 CENPI

2.04e-0418428353b71c4ac86dc5e42763b8f64fbc917177531017
ToppCelldroplet-Skin|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELOVL4 CFAP57 DSP

2.08e-04185283657fd191ed160f8620d57b33820ec7222806f289
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ATG4C LGI2 FRMD4B

2.08e-041852838207f9eff113eed429e961748c6b17d672a13b33
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ELOVL4 ABCC9 LGI2

2.11e-041862837c1807fca590cdccf7f5734460bac228d33964ca
ToppCelldroplet-Limb_Muscle-nan-24m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBOAT2 UNC80 KCNJ10

2.11e-04186283ea936e66ae4b7b40564711fad60ac0137327995f
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SIRPA VPS13C FGL2

2.11e-0418628323b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCelldroplet-Heart-nan-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOX4 ABCC9 CFAP57

2.14e-041872832591fe1552cd10925ad1d8d1f062a057ce6bdad9
ToppCelldroplet-Thymus-nan-18m-Myeloid-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP KCNJ10 TBC1D2

2.14e-04187283ed69e7cbd6fb59363b0e26f24887fc49405397ce
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ATG4C SIRPA FGL2

2.14e-0418728339b99f46b723f7f3c44880d7fe8642cbad558b8a
ToppCelldroplet-Limb_Muscle-nan-24m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBOAT2 UNC80 KCNJ10

2.14e-04187283a0bd2b0ec9e73521c245037b1dd51ff8cf24cbf5
ToppCelldroplet-Heart-nan-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOX4 ABCC9 CFAP57

2.14e-0418728359313a47a6012b2413d7d3673bb05fb7e49fd88f
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Pleural_Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

SIRPA KCNJ10 FGL2

2.14e-0418728388fac9f23047892acccbcc355d02ff079596fedf
ToppCelldroplet-Limb_Muscle-nan-24m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBOAT2 UNC80 KCNJ10

2.14e-04187283f2af79a20438108c814a73f9e24cd986d537237f
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCNT3 DSP KCNJ10

2.18e-04188283315ce1736e3a84a63a8d5dfa70d411b501cb2532
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP MBOAT2 KCNJ10

2.18e-0418828314e120b20e76baa07b6510a94f0c2dcdfdd52357
ToppCell(2)_NK/T-(210)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

MBOAT2 FGL2 TBC1D2B

2.21e-04189283fa72e87e1e8cd7cbddae7b47e19cf90d181820a7
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOX4 FRMD4B UNC80

2.21e-0418928332e6d6285b258831b965281224ff2aaeecdcb5f5
ToppCell(2)_NK/T-(21)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

MBOAT2 FGL2 TBC1D2B

2.21e-04189283b37ad24898a14a4a3b2d6cea2637de2471f76e20
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP MBOAT2 KCNJ10

2.21e-04189283443359d90fafae0c1de6bdcce9e8c95df6ea4de8
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOX4 FRMD4B UNC80

2.21e-04189283385ef7bbd76c8047aeecf6542377d4213b5da5db
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBOAT2 UNC80 KCNJ10

2.25e-04190283ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SIRPA DSP FGL2

2.25e-041902839ce301841ce9486701fa28eb2a9929e35d476878
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBOAT2 UNC80 KCNJ10

2.25e-041902834971857eac9af17d66d673ed2ab7072639f60a10
ToppCellwk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GCNT3 DSP UNC80

2.25e-04190283b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SIRPA DSP FGL2

2.32e-04192283b016e229300c183e14c0e2bba494bf49c7899112
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SIRPA DSP FGL2

2.32e-04192283ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GCNT3 DSP FGL2

2.32e-04192283967122c53af25b8f19a8411b4553d764c8d51c4d
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LGI2 UNC80 FGL2

2.35e-04193283f27e2be497745098b5269aa799dd3d5f62d78ba7
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LGI2 UNC80 FGL2

2.35e-041932834ccf984baebbb13ae916727137ce593fda7514a2
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOX4 ABCC9 LGI2

2.35e-04193283d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCellControl-Myeloid-MoAM4|Myeloid / Condition, Lineage and Cell class

MBOAT2 FRMD4B FGL2

2.39e-041942837ab808dd1876b0eec2831caa16d04fd859b1dc50
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LGI2 FRMD4B FGL2

2.39e-041942837b6a34d1f8922b71dcc931421666c1822cec8345
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LGI2 FRMD4B FGL2

2.39e-04194283435406ebe626c702f7d5a99a3d68ee85aa09be95
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LGI2 FRMD4B FGL2

2.39e-0419428348c37251518f96524807b5bd1bbc2820637666ad
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SIRPA FRMD4B FGL2

2.39e-04194283ad72be9f6871b334e1f477d868c15e7792fadea5
ToppCell10x5'v1-week_14-16-Endothelial-stroma-proliferating_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

NOX4 ABCC9 LGI2

2.39e-041942838a4be91414a2e69dd410aa75791f16008204c9a1
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NXPE1 DSP MBOAT2

2.42e-04195283c5f33b420c9ac14dc67fea632b8c2bc2442cbf3d
ToppCellControl-Myeloid-MoAM4|Control / Condition, Lineage and Cell class

MBOAT2 FRMD4B FGL2

2.42e-04195283211a736acbe875bd3c1942c62aaacc9b170ece6d
ToppCellMonocytes-M2-like_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

SIRPA LGI2 FRMD4B

2.42e-0419528310fa47bdcf6c9784ea930b75a5861e139421feed
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LGI2 FRMD4B FGL2

2.42e-041952834008fa86b5166087a4b20f89ae07e1dfc87c855d
ToppCell(3)_MNP-(3)_Macrophage_MARCOneg|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

LGI2 FRMD4B FGL2

2.42e-04195283e4b5e4b8832669fb4d1661ecd828b81e621d35c4
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C DYNC1H1 UNC80

2.42e-041952833e519cffa6144a62b06124642a14c9ff39b76554
ToppCellMonocytes-NUPR1+_Monocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SIRPA FRMD4B TBC1D2

2.42e-041952835e12201ce7ba912e7faa123ca200e609252ba288
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-Goblet_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NXPE1 DSP MBOAT2

2.42e-04195283219c5d0cde7f6082755154f54db221413ec555cb
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C DYNC1H1 UNC80

2.42e-041952837796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-MMP9+_Inflammatory_macrophage|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SIRPA KCNJ10 FGL2

2.42e-041952835a7c74f96f213c504abd65e751800da7e03e47d9
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-mature_enterocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NXPE1 GCNT3 DSP

2.46e-04196283153326be031a58b720da4dab57edd8936d513f8e
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NXPE1 GCNT3 DSP

2.46e-04196283b7748618aaf3ace40940be1b6ca2148e941541a2
ToppCellnormal_Lung-Myeloid_cells-mo-Mac|normal_Lung / Location, Cell class and cell subclass

LGI2 FRMD4B FGL2

2.46e-041962834d3a3264b3d781139899448cde3b7a4f214ca14d
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SIRPA CHRNA3 CENPI

2.50e-04197283d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCellMonocytes-NUPR1+_Monocytes|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SIRPA LGI2 TBC1D2

2.50e-041972838a058c9d9285acd7cf2fb8e34f7602a86b5d6c89
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GCNT3 DSP MBOAT2

2.50e-04197283adb4e27d73ae2e6a39d212c0ead3ac0ad62d9131
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DSP KCNJ10 FGL2

2.50e-0419728302cc9d39afefa5e5b6f5d93f9adc3a20050b70dd
ToppCellnormal_Lung-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

LGI2 FRMD4B FGL2

2.54e-04198283fbd72ebaba73cc30e79dc8a8c3d46b6f863c1494
ToppCell3'-Adult|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NXPE1 GCNT3 DSP

2.54e-04198283302adb42089ff22fffc4f01af572ca2e151f7ce7
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_macrophage|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FRMD4B KCNJ10 FGL2

2.54e-041982839aaff68107ae4542f904b142d23669f2fcd557ac
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FRMD4B KCNJ10 FGL2

2.54e-041982835aaf3861c53763cf09bb628c9d2eabb6a7277021
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GCNT3 DSP MBOAT2

2.57e-041992838bf8d7cd774479f065bbbbcb5a4bd1aa91aa0d85
ToppCellwk_20-22-Hematologic-Myeloid-SPP1+_Mac|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SIRPA FRMD4B FGL2

2.57e-041992837c19f1b1f4369edd035ca9cdcf4e653771fc4648
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GCNT3 DSP MBOAT2

2.57e-041992830c060ef64341659f4b1247d0264ac12e53a7e12e
ToppCell(00)_Basal-(1)_GFP|(00)_Basal / shred by cell type by condition

SIRPA GCNT3 MBOAT2

2.57e-04199283105b15157f35df3fdf857e306f11e4e8200e05d4
ToppCellCOVID-19_Mild-Neu_0|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

FGL2 TBC1D2B

7.12e-04632821ab77b6f098686bc168427159282bbf3538d4292
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

EP300 FGL2

8.29e-0468282f1cbc6d72489272c1eb6200f64b8b6444719acda
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sfrp2-Inhibitory_Neuron.Gad1Gad2_Id2.Sfrp2_(Interneuron,_Neurogliaform1)|Hippocampus / BrainAtlas - Mouse McCarroll V32

NOX4 CHRNA3

9.55e-0473282cc89c94a3768b02036757dea86989d9284b214b9
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sfrp2|Hippocampus / BrainAtlas - Mouse McCarroll V32

NOX4 CHRNA3

9.55e-04732826f28d52700bab981c8a3664ba4762f3572f7e788
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sfrp2-Inhibitory_Neuron.Gad1Gad2_Id2.Sfrp2_(Interneuron,_Neurogliaform1)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

NOX4 CHRNA3

9.55e-0473282ae80fcf3544c18fe0318a8311e96f2448f7cb03c
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)|Hippocampus / BrainAtlas - Mouse McCarroll V32

NOX4 ABCC9

1.48e-039128278e2e65beb15bf1e251974c72fbcfab817492772
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Kcnj8_(Mural.Rgs5Acta2.Kcnj8)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

NOX4 ABCC9

1.48e-0391282f59908093416ca7b3ca27019d71c79acbdea18cb
ToppCellHippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

NOX4 ABCC9

1.48e-0391282104d2ab9fe5cc404388c32fafb34e421c2e138be
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EP300 KCNJ10

1.71e-039828295162072f3afc95e46f29db3d79ebd930bc09726
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Gpr50|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CHRNA3 RNF133

1.82e-031012826523c314166dcf66c3ed13c02ca4b886b068e5b8
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SACS FGL2

2.15e-031102820b39f3c358715e6e7288d3e4a0f3e7c0e877333c
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

EMC1 CFAP57

2.30e-03114282fceb7cc590a47380145fc0d854c9f2350dbb0a59
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pdgfa_(Mural.Rgs5Acta2.Pdgfa)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

EMC1 CFAP57

2.30e-031142822cc5d2da5573650c5232a01e2d2128082c4bffcb
DrugTrimethobenzamide hydrochloride [554-92-7]; Up 200; 9.4uM; PC3; HT_HG-U133A

GCNT3 FRMD4B RRP12 FGL2 TBC1D2

3.85e-061972854100_UP
Diseasediabetic retinopathy (implicated_via_orthology)

EP300 KCNJ10

8.89e-0516262DOID:8947 (implicated_via_orthology)
Diseasedilated cardiomyopathy (is_implicated_in)

ABCC9 DSP

6.59e-0443262DOID:12930 (is_implicated_in)
Diseaseage at assessment, pelvic organ prolapse

ABCC9 SACS

6.59e-0443262EFO_0004710, EFO_0008007
DiseaseAlcohol Use Disorder

TAS2R38 CHRNA3

6.90e-0444262C0001956
DiseaseCardiomyopathy

ABCC9 DSP

7.88e-0447262cv:C0878544

Protein segments in the cluster

PeptideGeneStartEntry
IWLMFNNAWLYNRKT

EP300

1121

Q09472
METNLWLKQIWNDYK

CHRNA3

81

P32297
NLLSKATYWWMNTLI

ABCC9

221

O60706
FISAWNNMKYSWVLK

ATG4C

16

Q96DT6
WTTFIDMQWRYKLLL

KCNJ10

56

P78508
MFLDNWNIQTALWLK

MBOAT2

336

Q6ZWT7
YLWWKRYLTMLQLIQ

ELOVL4

211

Q9GZR5
SNLVYWLWEKQKVMA

CFAP57

131

Q96MR6
IWLSMNVLLFWKTFL

NOX4

21

Q9NPH5
VVTSWNLPMSYWLNN

PORCN

301

Q9H237
WYANSSLIKSIWVMA

FRMD4B

336

Q9Y2L6
LWNQLYINMKSLVSW

DSP

536

P15924
MVQWKRLCQLHYLWA

GCNT3

1

O95395
MKLANWYWLSSAVLA

FGL2

1

Q14314
VKVWLQYQCLWDMQA

DYNC1H1

1051

Q14204
QLILLQAWTSHLWKM

EMC1

491

Q8N766
SLKELLQNWLLWLSM

CENPI

496

Q92674
VSWLKMVWKNLYIHF

SACS

776

Q9NZJ4
TWMIFIISQNFTKLW

NXPE1

21

Q8N323
IMLWMIANQANLWLA

TAS2R38

96

P59533
SWLMKFSVLWLVSQN

RNF133

16

Q8WVZ7
KWLYLWLKMTNSTVS

LGI2

176

Q8N0V4
KDGTYNWMSWLLVNV

SIRPA

306

P78324
ESKIYDTLQWQMWTL

RRP12

611

Q5JTH9
SQWYWLSLQVKEMAL

UNC80

2811

Q8N2C7
IRRYTQMWSWSNIKK

VPS13C

386

Q709C8
LMTYWLQELQQKRWE

TBC1D2B

126

Q9UPU7
LYWLQQLQMKRWEFH

TBC1D2

131

Q9BYX2