Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenocholestasis

SOX17 SIK3 ATXN2

1.42e-069373MP:0000610
MousePhenoabnormal gallbladder epithelium morphology

SOX17 SIK3

2.04e-053372MP:0009492
MousePhenoabnormal bile duct physiology

SOX17 SIK3 ATXN2

3.77e-0525373MP:0003252
MousePhenointrahepatic cholestasis

SIK3 ATXN2

6.78e-055372MP:0005415
DomainCyt_P450_E_grp-I

CYP3A7 CYP2F1

5.26e-0345452IPR002401
DomainTF_fork_head_CS_2

FOXD4L1 FOXD4L3

5.49e-0346452IPR030456
DomainTF_fork_head_CS_1

FOXD4L1 FOXD4L3

5.73e-0347452IPR018122
DomainFORK_HEAD_3

FOXD4L1 FOXD4L3

6.21e-0349452PS50039
DomainFH

FOXD4L1 FOXD4L3

6.21e-0349452SM00339
DomainFORK_HEAD_1

FOXD4L1 FOXD4L3

6.21e-0349452PS00657
DomainFORK_HEAD_2

FOXD4L1 FOXD4L3

6.21e-0349452PS00658
DomainForkhead

FOXD4L1 FOXD4L3

6.21e-0349452PF00250
DomainFork_head_dom

FOXD4L1 FOXD4L3

6.21e-0349452IPR001766
DomainSMAD_FHA_domain

PHF12 SMAD6

6.97e-0352452IPR008984
DomainCyt_P450_CS

CYP3A7 CYP2F1

7.23e-0353452IPR017972
DomainCYTOCHROME_P450

CYP3A7 CYP2F1

8.33e-0357452PS00086
Domainp450

CYP3A7 CYP2F1

8.61e-0358452PF00067
DomainCyt_P450

CYP3A7 CYP2F1

9.19e-0360452IPR001128
DomainProtein_kinase_ATP_BS

MAP3K9 SIK3 MERTK STK35

1.29e-02379454IPR017441
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PPP1R26 RGMA ESRP2 SEMA4F TNRC18 EDC4 ITGA5 MBD6 EP400 ZNF865 PHF12 GGT7

1.87e-081105471235748872
Pubmed

cDNAs with long CAG trinucleotide repeats from human brain.

TNRC18 EP400 ATXN2

4.02e-06234739225980
Pubmed

Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm.

FOXD4L1 FOXD4L3

2.67e-05647227092474
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

TNRC18 EP400 ATF2 PHF12 RAVER1

3.08e-0526847533640491
Pubmed

The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization.

FOXD4L1 FOXD4L3

4.98e-0584728530406
Pubmed

An amphioxus winged helix/forkhead gene, AmphiFoxD: insights into vertebrate neural crest evolution.

FOXD4L1 FOXD4L3

6.40e-05947212412011
Pubmed

Gene content and function of the ancestral chromosome fusion site in human chromosome 2q13-2q14.1 and paralogous regions.

FOXD4L1 FOXD4L3

9.75e-051147212421752
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TNRC18 EDC4 TMED10 EP400 ATXN2 ATF2 PHF12 RAVER1

1.05e-04110347834189442
Pubmed

Human transcription factor protein interaction networks.

SOX17 EDC4 TMED10 ERF MBD6 EP400 ATXN2 PHF12 RAVER1

1.08e-04142947935140242
Pubmed

Interaction network of human early embryonic transcription factors.

TNRC18 ERF MBD6 EP400 PHF12

1.10e-0435147538297188
Pubmed

MRG15 is a novel PALB2-interacting factor involved in homologous recombination.

EP400 PHF12

1.17e-041247219553677
Pubmed

Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.

FOXD4L1 FOXD4L3

1.38e-04134727957066
Pubmed

A genetic study of the suppressors of the Engrailed-1 cerebellar phenotype.

FOXD4L1 FOXD4L3

1.38e-041347216884697
Pubmed

Six members of the mouse forkhead gene family are developmentally regulated.

FOXD4L1 FOXD4L3

1.86e-04154727689224
Pubmed

Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.

FOXD4L1 FOXD4L3

1.86e-041547222045912
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

SIK3 ITGA5 BSN SEC31B PHF12 RAVER1

2.11e-0463847631182584
Pubmed

Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system.

FOXD4L1 FOXD4L3

2.12e-04164728861101
Pubmed

Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.

FOXD4L1 FOXD4L3

2.12e-041647210208738
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

TNRC18 BSN EP400 ATXN2 PIK3R2

2.82e-0443047535044719
Pubmed

Functional equivalency between Otx2 and Otx1 in development of the rostral head.

FOXD4L1 FOXD4L3

3.01e-04194729895322
Pubmed

Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology.

TCAF1 ATXN2

3.01e-041947234467244
Pubmed

Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.

FOXD4L1 FOXD4L3

3.34e-042047212812790
Pubmed

Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification.

FOXD4L1 FOXD4L3

3.69e-04214729449667
Pubmed

p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation.

ITGA5 ATF2

4.06e-042247216751104
Pubmed

Diverse fates of paralogs following segmental duplication of telomeric genes.

FOXD4L1 FOXD4L3

4.06e-042247215233989
Pubmed

Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.

FOXD4L1 FOXD4L3

4.06e-042247217389379
Pubmed

MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks.

EP400 PHF12

4.44e-042347220332121
Pubmed

Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.

EP400 PHF12

4.44e-042347222038470
Pubmed

Otx2 is required to respond to signals from anterior neural ridge for forebrain specification.

FOXD4L1 FOXD4L3

4.84e-042447211820816
Pubmed

A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.

FOXD4L1 FOXD4L3

4.84e-042447229992973
Pubmed

Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.

FOXD4L1 FOXD4L3

5.69e-042647215857913
Pubmed

Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways.

ATF2 PIK3R2

5.69e-042647221367821
Pubmed

EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition.

SOX17 ITGA5

7.09e-042947218794329
Pubmed

Molecular profiling of synovial joints: use of microarray analysis to identify factors that direct the development of the knee and elbow.

FOXD4L1 FOXD4L3

7.09e-042947222972626
Pubmed

SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning.

TM7SF2 SMAD6

7.09e-042947234822715
Pubmed

Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development.

PIK3R2 SMAD6

7.59e-043047238310234
Pubmed

Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.

CES3 CYP3A7

7.59e-043047220529763
Pubmed

Evidence Implicating CCNB1IP1, a RING Domain-Containing Protein Required for Meiotic Crossing Over in Mice, as an E3 SUMO Ligase.

EP400 PHF12

1.03e-033547221779533
Pubmed

Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry.

CES3 MERTK

1.03e-033547215188402
Pubmed

Monitoring protein-protein interactions between the mammalian integral membrane transporters and PDZ-interacting partners using a modified split-ubiquitin membrane yeast two-hybrid system.

PRSS8 TMED10

1.22e-033847218407958
Pubmed

Interactome Analysis of the Nucleocapsid Protein of SARS-CoV-2 Virus.

EDC4 TMED10 ATXN2

1.31e-0315947334578187
Pubmed

A census of human transcription factors: function, expression and evolution.

SOX17 HES4 ERF FOXD4L1 FOXD4L3 ATF2

1.34e-0390847619274049
InteractionTOP3B interactions

PPP1R26 RGMA ESRP2 SEMA4F TNRC18 EDC4 ITGA5 MBD6 EP400 ATXN2 ZNF865 PHF12 GGT7

1.64e-0514704613int:TOP3B
InteractionGUSBP5 interactions

TNRC18 ERF ATXN2 PHF12

2.56e-0575464int:GUSBP5
Cytoband16q22.1

CES3 ESRP2 EDC4

2.01e-0411047316q22.1
Cytoband19q13.2

CYP2F1 TMEM145 FAM98C

6.47e-0416447319q13.2
CytobandEnsembl 112 genes in cytogenetic band chr16q22

CES3 ESRP2 EDC4

8.88e-04183473chr16q22
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZBTB32 ERF CYP2F1 ZNF865 TMEM145 FAM98C

1.31e-031192476chr19q13
GeneFamilyAtaxins|Trinucleotide repeat containing

TNRC18 EP400 ATXN2

1.24e-0525333775
CoexpressionDELACROIX_RARG_BOUND_MEF

TNFRSF12A PRSS8 TNRC18 MBD6 ATXN2 PIK3R2 WNT10B SMAD6

2.62e-07366478M2461
CoexpressionDELACROIX_RARG_BOUND_MEF

TNFRSF12A PRSS8 TNRC18 MBD6 ATXN2 PIK3R2 WNT10B SMAD6

3.34e-07378478MM1077
CoexpressionGSE45365_CTRL_VS_MCMV_INFECTION_NK_CELL_UP

TM7SF2 DDAH2 TCAF1 MERTK CYP2F1

2.91e-05200475M10026
ToppCelldroplet-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 RGMA DDAH2 ITGA5 SMAD6

1.19e-06177475a5b54792ef948a1e1de66301a60e051250189f59
ToppCell(09)_Interm._secr.>cil.-(0)_Reference|(09)_Interm._secr.>cil. / shred by cell type by condition

MAP3K9 ERF MBD6 CYP2F1 GGT7

1.74e-06191475e63432718d62d39165ba8a66e14bb38c93907ffe
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor-epi-airway_progenitor_early|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RGMA TM7SF2 ESRP2 HES4 PRSS8

2.02e-061974754ae08ccb6f1da626c4f0fb0140a2811cb6e31ba1
ToppCell390C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SOX17 TNFRSF12A HES4 ITGA5 SMAD6

2.18e-06200475c32ad15dede3f879007c0b856f2fed1f5b058103
ToppCell390C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SOX17 TNFRSF12A HES4 ITGA5 SMAD6

2.18e-062004758a2c6c53a39fab86750526083f7254b7413b29af
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)|Striatum / BrainAtlas - Mouse McCarroll V32

SOX17 ESRP2 SLC9B1 SMAD6

3.66e-06994740d5684978f34258d4eb4941eb6c60393a9bc84ed
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)--|Striatum / BrainAtlas - Mouse McCarroll V32

SOX17 ESRP2 SLC9B1 SMAD6

3.66e-06994741244f50bb66eea555a284ff5c35ac755d1e9080d
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)-|Striatum / BrainAtlas - Mouse McCarroll V32

SOX17 ESRP2 SLC9B1 SMAD6

3.66e-06994740c27df8ecc1956b056930da9ab1c96df7fb9f7b5
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX17 WSCD1 SIK3 SMAD6

3.09e-0517047455fe16d98ea284d05fb899888e4569c685644c7b
ToppCelldroplet-Kidney-nan-21m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 DDAH2 TCAF1 SMAD6

3.78e-05179474ba38177ffcf3a20f02afeeaaa91bc8eab8d1ac05
ToppCelldroplet-Kidney-nan-21m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 DDAH2 TCAF1 SMAD6

3.78e-05179474d121351b4c3b91108e6c5753d18a44d676f38d4c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPP1R26 HES4 ZNF865 STK35

3.86e-05180474c72f15763ba707189e29c85db533557f01c7fdb1
ToppCellfacs-Bladder-nan-18m|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 TNFRSF12A WSCD1 ERF

4.30e-051854743e00879466e626aa8604efecfc4678d64f54dbfc
ToppCellfacs-Bladder-nan-18m-Epithelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 TNFRSF12A WSCD1 ERF

4.30e-051854743dc5812c961ff209f197ff4cbfb90009c0537550
ToppCellCD8+_Memory_T_cell-FLU-0|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

TNFRSF12A TM7SF2 DDAH2 ZBTB32

4.39e-05186474b5edd4ec462c7cd87f567b8b6f86259ddbbf096d
ToppCellE12.5-Epithelial|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TNFRSF12A ESRP2 SEMA4F PRSS8

4.48e-0518747429ea5e14dac3321df76f6aa4f053068b49c4a4bf
ToppCellE12.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TNFRSF12A MAP3K9 ESRP2 PRSS8

4.48e-05187474baff4edc1bf64e3e03864a434fa47075ff7372fd
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 DDAH2 SMAD6

4.48e-0518747452ffd4be374e329ac8d321063f061b826d252956
ToppCelldroplet-Lung-LUNG-30m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 DDAH2 SMAD6

4.67e-0518947425db316f66cee53774bb2b286cc457b37353356c
ToppCelldroplet-Kidney-nan-21m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 DDAH2 SLC9B1 SMAD6

4.67e-051894742ce330d8078833c05775c481e73770f9ee4a5c88
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX17 MERTK ITGA5 SMAD6

4.67e-05189474b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCelldroplet-Kidney-nan-21m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 DDAH2 SLC9B1 SMAD6

4.67e-05189474473c87036e04a058b4a5138438b7ba7e1e766799
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX17 MERTK ITGA5 SMAD6

4.67e-05189474c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCelldroplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 DDAH2 SMAD6

4.77e-05190474e64b191f928935484e2c993d7f8af0572a617a3a
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX17 MERTK ITGA5 SMAD6

4.77e-05190474aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SOX17 HES4 TMED10 SMAD6

4.97e-05192474aedddccacf60e884af044cefba6c64ca10ac97d2
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SOX17 HES4 TMED10 SMAD6

4.97e-05192474389d5e6d0689371bfe1d0b06e92e0e6e5573567b
ToppCellfacs-Lung-nan-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESRP2 SEMA4F PRSS8 CYP2F1

4.97e-05192474cca2d0fedfbd946c54d6f4fc45887117c8dae58a
ToppCelldroplet-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 DDAH2 SMAD6

4.97e-0519247442e4dafbe3e8b4a3c25d594f06b95430a1dd8b28
ToppCellPCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TNFRSF12A TM7SF2 ESRP2 PRSS8

4.97e-05192474c15841f35e24d6ef6ce2a9a6dc62e66efdc3d9d5
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 DDAH2 SMAD6

5.07e-05193474ff048e7fbab95d7914f3a636f6f014e7115d63d8
ToppCelldroplet-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 DDAH2 SMAD6

5.07e-051934747cff1e859b296b1032eebcfc0f99a504f3bda2c9
ToppCelldroplet-Lung-nan-18m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 DDAH2 SMAD6

5.07e-051934742f387fb763448b7c351da19a55765375e782c790
ToppCelldroplet-Lung-nan-21m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 DDAH2 SMAD6

5.07e-05193474ae35c5757a88b02f8b9f94a0af4c3396ca828cc3
ToppCelldroplet-Lung-nan-21m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 DDAH2 SMAD6

5.07e-051934744893b922e129711d5886bd4f3ee106e9e7065971
ToppCelldroplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 DDAH2 SMAD6

5.07e-051934748748af38bfbbbb431ff9d9d5fa75934b5869293a
ToppCellfacs-Lung-3m-Epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESRP2 SEMA4F PRSS8 CYP2F1

5.07e-05193474db5e43e0b571737e7006365bdf0575340b8b900b
ToppCelldroplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 DDAH2 SMAD6

5.07e-05193474ab54c4b8ae17580e2f2bfcdcb1456fe52dedafe9
ToppCelldroplet-Lung-21m-Endothelial-capillary_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.17e-051944740d72cb6183062d48488c73320e48044d070fbcac
ToppCelldroplet-Lung-LUNG-1m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 DDAH2 SMAD6

5.17e-0519447468efc6df31479839a3bd5fe9fbc98ddceecc3b10
ToppCellGoblet|World / shred by cell class for turbinate

TM7SF2 HES4 PRSS8 CYP2F1

5.17e-0519447403b62e7cff5e7a6e7bd7d9dda273c74bf9c1f42e
ToppCelldroplet-Lung-1m-Endothelial-capillary_endothelial-capillary_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.17e-05194474e13923860a64ba9cf32df53c9f0cf4e7c321881d
ToppCelldroplet-Lung-nan-18m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 DDAH2 SMAD6

5.17e-05194474faaa7f18667e8943528fd0e92b7988e5b0607b54
ToppCelldroplet-Lung-21m-Endothelial-capillary_endothelial-capillary_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.17e-051944741a637809c0ec97374839c3476527e87eea75ed20
ToppCelldroplet-Lung-21m-Endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.17e-05194474b45aebbc7641df0bf56d0c2e88821f1daf705449
ToppCelldroplet-Lung-30m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.17e-05194474fc3f81b5bdc544a69c355e482f002643e029a7b0
ToppCelldroplet-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.17e-05194474ff076902578997565d72dc40b0b80ae76d6ab2b4
ToppCelldroplet-Lung-18m-Endothelial-capillary_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.17e-05194474627432da2e00dc4256f48a6388ce78e7b5e7a51e
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 DDAH2 SMAD6

5.17e-05194474f6c9cc362ccdbc7e790f7c8d1c56cab3557c5306
ToppCelldroplet-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.17e-05194474b49c19c33ad2e391d9367a4a2695b2fe87dd8a08
ToppCelldroplet-Lung-LUNG-1m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 DDAH2 SMAD6

5.17e-0519447403985e4ab10f140f758e70dc7bfaa059b4e3bb18
ToppCelldroplet-Lung-1m-Endothelial-capillary_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.17e-0519447486508dd9b9d345b6624d185048cc92b81dd11c2a
ToppCelldroplet-Lung-1m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.17e-051944741ac52b00ea0b0ddbd04f5d85fa8c086980a78926
ToppCelldroplet-Lung-1m-Endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.17e-05194474b1a25e3b36e7b7e558ef95ec22a3bdcbceae821f
ToppCelldroplet-Lung-18m-Endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.17e-05194474fd4548db0f12170b636186e6af90666f7e26c0ad
ToppCelldroplet-Lung-21m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.27e-0519547427d1f228103ff5d8941aa8a8d15726cd09298a30
ToppCelldroplet-Lung-30m-Endothelial-capillary_endothelial-capillary_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.38e-051964749e737eaa98fd49972fce64d1d4a4d1f34b9bcb96
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Club|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TNFRSF12A ESRP2 PRSS8 CYP2F1

5.38e-051964744e4c632db73b1340d80bf40a7657cb4821084d3c
ToppCell(6)_Endothelial_cells-(6)_Endothelial-B_(Artery)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

SOX17 TNFRSF12A HES4 SMAD6

5.38e-05196474f540cf17b4405a6dd38d2b6123e6541d0aac889e
ToppCelldroplet-Lung-30m-Endothelial-capillary_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.38e-0519647499a7f2e57774884216525897dcd32a289107548b
ToppCelldroplet-Lung-30m-Endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX17 WSCD1 DDAH2 SMAD6

5.38e-0519647458871891185aa7e1e4ab9b99cd25c1ca3c932cc8
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Serous-Serous|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CES3 TM7SF2 PRSS8 TMED10

5.49e-0519747440bd7c314ff5254d87737822078e7b9eaf23edf3
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Serous|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CES3 TM7SF2 PRSS8 TMED10

5.49e-05197474d3539607d5477f5dfd85f1fa99b74677c0fa8937
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX17 WSCD1 ITGA5 SMAD6

5.71e-05199474b15304d3d3f6c254969b54a61bee3d9f368840b2
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TM7SF2 HES4 PRSS8 CYP2F1

5.82e-05200474133853d0f55c63ebe94dd54151f9f1f90650a0d8
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TM7SF2 HES4 PRSS8 CYP2F1

5.82e-052004748f811ddd84c037a250d124496b0fbb2e4717011c
ToppCellASK452-Epithelial-Secretory|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

PPP1R26 SLC9B1 CYP2F1

3.64e-0413247349ba24e24b3127b5257a88a0ee0246c9843c580a
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK|Striatum / BrainAtlas - Mouse McCarroll V32

SOX17 SLC9B1 SMAD6

4.06e-04137473d37f425b13bc046baa1f8619b98a16b936f88ff6
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Striatum / BrainAtlas - Mouse McCarroll V32

SOX17 SLC9B1 SMAD6

4.06e-04137473306b11b3b9e5fd562d845fb5eaa4ac982864efce
ToppCellPCW_05-06-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CES3 TM7SF2 ESRP2

4.33e-041404738abbd5dc799943b49cd0045d0da405c3f3d0db6b
ToppCellPCW_05-06-Epithelial-Epithelial_ciliated|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CES3 TM7SF2 ESRP2

4.33e-04140473e4689232c473d239b07a7fbcaaa3414fbd9badea
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SLC9B1 MERTK SMAD6

5.50e-04152473ca23261d8ef263cc697b8d7e7cb2afec8bc564f2
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT2_Precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

ESRP2 SEMA4F PRSS8

5.82e-041554739cad73d0b8ead289e1073d1a2e00bbeb1228308c
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PPP1R26 TNFRSF12A MERTK

6.04e-04157473432b8719a8afd289cf48068e12c26a349d753fcc
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WSCD1 SIK3 MERTK

6.04e-04157473a426c54fd1545093d41426e9620862f71bd06f6b
ToppCellStriatum-Neuronal-Inhibitory|Striatum / BrainAtlas - Mouse McCarroll V32

PPP1R26 MAP3K9 TMEM145

6.04e-04157473c41ff3fe9de7187575114febfe9bd8733366fb8a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HES4 MERTK ITGA5

6.15e-041584731635a85fc73c544028418087f36d28957dd4f458
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HES4 MERTK ITGA5

6.15e-0415847380841dadfa53bcde36a3e486408a095f78e772eb
ToppCellP15-Epithelial-epithelial_progenitor_cell-epi_progenitor|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MAP3K9 SLC9B1 WNT10B

6.27e-04159473a4bfd59c53237964fc24a24de5c1925fdd01db99
ToppCellSevere-Lymphoid-NK-Proliferating_T|Severe / Condition, Lineage, Cell class and cell subclass

SEMA4F ZBTB32 FAM98C

6.38e-04160473cb2276d9bd78508644420e9580d3c17b914224cb
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SLC9B1 MERTK SMAD6

6.38e-0416047319105debef96ea0c267d6a1d332303ec668ae47e
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TM7SF2 MAP3K9 HES4

6.50e-041614737c9d4410d7142a5f3a05418c994f69978c9ffa17
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX17 WSCD1 SMAD6

6.61e-0416247325bb1b9709f960fdf90faff56e874f52a8f5d17e
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

SOX17 WSCD1 ITGA5

6.73e-04163473d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SOX17 WSCD1 SMAD6

6.85e-041644733cd80e6275f0f9b5667912139d15ebf5e6b17f2f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DDAH2 EDC4 FAM98C

6.98e-041654737fe24be5bae7f0344243fb06cdfa02b4ddbb5a19
ToppCellfacs-Trachea-nan-18m-Epithelial-mucus_secreting_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS8 MBD6 TMEM145

6.98e-041654737e7643834ed483aec04f513cca38d6367fda9ff8
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TM7SF2 PRSS8 GGT7

7.10e-0416647389e2b8453180983533faccb4275867861876d7ee
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

PPP1R26 TNFRSF12A MERTK

7.22e-04167473b5d15773be32cd277125fd3b4056a8fefaefa5ec
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HES4 SLC9B1 PRSS8

7.22e-04167473d1a13d6ada572d8ddb2da95e6e122d2b705fad7f
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D231|Adult / Lineage, Cell type, age group and donor

SOX17 HES4 SMAD6

7.35e-04168473aca34c51758c65925ad24110294a72b2dea6db72
ToppCelldroplet-Pancreas-Exocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGMA DDAH2 PRSS8

7.35e-04168473100ab6d36592b61f4db9f8cb90c48afac016d679
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D122|Adult / Lineage, Cell type, age group and donor

SOX17 WSCD1 SMAD6

7.35e-041684738c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Endothelial-new-cluster|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 SMAD6

7.61e-041704734fb4ce46e4fa2418238e264875209d7ebe844d82
ToppCellmetastatic_Brain-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

HES4 ZBTB32 ERF

7.74e-041714730d14bc9688c427ba2265984987dc3eea195b19eb
ToppCellE12.5-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TNFRSF12A SEMA4F PRSS8

7.74e-04171473a4d6b0f57eead11b01153688b06b2a45a3b488f2
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WSCD1 HES4 PHF12

7.74e-04171473b51bbeacb172e8b5de519ada85543d7ae9914b3c
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SOX17 WSCD1 SMAD6

7.87e-04172473de9b11ab109d04937186c09772cec9105a935f95
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PPP1R26 MAP3K9 PRSS8

8.00e-0417347345808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Endothelial-endothelial_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX17 WSCD1 SMAD6

8.00e-041734732a5ea28c65dd4ee03ba3d0bfe0c819b1d583f8da
Diseasecraniosynostosis (is_implicated_in)

ERF SMAD6

1.42e-0412442DOID:2340 (is_implicated_in)
DiseaseTrigonocephaly

ERF SMAD6

2.57e-0416442C0265535
DiseaseScaphycephaly

ERF SMAD6

2.57e-0416442C0265534
DiseaseSynostotic Posterior Plagiocephaly

ERF SMAD6

2.57e-0416442C1833340
DiseaseSynostotic Anterior Plagiocephaly

ERF SMAD6

2.57e-0416442C2931150
DiseaseMetopic synostosis

ERF SMAD6

2.57e-0416442C1860819
DiseaseCraniosynostosis, Type 1

ERF SMAD6

2.57e-0416442C4551902
DiseaseAcrocephaly

ERF SMAD6

2.57e-0416442C0030044
DiseaseBrachycephaly

ERF SMAD6

2.91e-0417442C0221356
DiseaseCraniosynostosis

ERF SMAD6

4.06e-0420442C0010278
Diseaseeye measurement

SEMA4F ATXN2

7.45e-0427442EFO_0004731
DiseaseAgouti-related protein measurement

CES3 ESRP2

7.45e-0427442EFO_0008016
DiseaseIGA Glomerulonephritis

MERTK HPSE

1.18e-0334442C0017661
Diseasefree cholesterol to total lipids in medium VLDL percentage

SIK3 ATXN2

3.29e-0357442EFO_0022284
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

SLC9B1 SIK3 ATXN2

5.44e-03239443EFO_0008317, EFO_0020945

Protein segments in the cluster

PeptideGeneStartEntry
PPDLGAFRGPPLARL

ERF

211

P50548
QVLQGPPLPRPLGFE

EP400

281

Q96L91
VPGPFPLLLHLPNGQ

ATF2

211

P15336
LLGAPPAMPLLNGPA

RAVER1

361

Q8IY67
PPGPRPLSILGNLLL

CYP2F1

31

P24903
SPRGLLPGLLPAPAD

EDC4

676

Q6P2E9
PTLAGPGGLFPPRLA

MBD6

176

Q96DN6
MGPAPLPLLLGLFLP

MERTK

1

Q12866
AALHNPRPGPLLGAP

FOXD4L3

226

Q6VB84
GLGGPPRPFVVLLLP

ATXN2

96

Q99700
LVPLRPGLLGNPTFP

BSN

2141

Q9UPA5
GRPPLPGSLLHRPDL

GGT7

296

Q9UJ14
LGPLSPGALPRPAQA

HPSE

21

Q9Y251
PARLLGPPASLPGLE

TM7SF2

41

O76062
LGATFGPLLLRAPPP

PIK3R2

246

O00459
LLLPPPPRVGGFNLD

ITGA5

31

P08648
LGLVLLLAGPRPPGP

LACTBL1

336

A8MY62
RPLLPSLGGPFPLLA

HES4

176

Q9HCC6
FPLLAPPLLPGLTRA

HES4

186

Q9HCC6
LQALGLPRPAPGTPA

FAM98C

161

Q17RN3
ALHNPRPGPLLGAPA

FOXD4L1

226

Q9NU39
LGIPGPTPLPFLGNA

CYP3A7

36

P24462
LFLRPGLPGVPPFLL

DDAH2

221

O95865
LGIPFAQPPLGPDRF

CES3

61

Q6UWW8
GAGLPPPLQNPLLLG

PRRT3

561

Q5FWE3
RPGLPALLPFQAGPL

MAP3K9

1046

P80192
LQFPEQGFPAGPPLL

SOX17

181

Q9H6I2
GPGQPTASPFPLLLL

SEMA4F

11

O95754
GGQPAPPQLLLGRLF

SMAD6

216

O43541
PGVSPLARFPGNLLL

TCAF1

371

Q9Y4C2
DPRRLPGANTPLPGL

PHF12

561

Q96QT6
LLPGFPGVNPQAPFL

SIK3

486

Q9Y2K2
LPGGFPQPLLPNLAE

SLC26A10

261

Q8NG04
PARGLPSLPLAGFSP

PPP1R26

1066

Q5T8A7
LFPLLPLRPLGPGRM

SEC31B

936

Q9NQW1
LLPIPFPLAPGTGRD

ESRP2

461

Q9H6T0
PAQGLLRPILFLPLG

PRSS8

316

Q16651
PGRAAAGLPLAPRPL

RGMA

421

Q96B86
AGPGLLPRKPPGLAA

TNRC18

966

O15417
EAGGARAAPLLLPPP

STK35

116

Q8TDR2
AAPERLLPPAPGGLQ

ZNF865

721

P0CJ78
GPPARRGPFPLALLL

TMED10

6

P49755
LQTFLLRLPPGAPGP

KBTBD13

436

C9JR72
PPLPPLLGMLLAGFT

SLC9B1

121

Q4ZJI4
PPAPFRLLWPILGGA

TNFRSF12A

71

Q9NP84
LRKLPGPLPPAGSLQ

ZBTB32

226

Q9Y2Y4
ALPQGPRAPGPLQTL

WSCD1

41

Q658N2
RPRPPPSGLAGLLFL

WNT10B

6

O00744
SGLPLFRDLRPPGPL

TMEM145

476

Q8NBT3
GFGGLDRLVLPPPPQ

nan

6

Q8TCH9