Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	SUMO ligase activity	RGPD2 RGPD8 RGPD1 ZMIZ1	3.00e-07	20	58	4	GO:0061665
GeneOntologyMolecularFunction	SUMO transferase activity	RGPD2 RGPD8 RGPD1 ZMIZ1	3.52e-06	36	58	4	GO:0019789
GeneOntologyMolecularFunction	GTPase activator activity	RGPD2 ARHGAP32 RGPD8 RGPD1 SIPA1L2 ARAP1 RGPD5	1.58e-05	279	58	7	GO:0005096
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	RGPD2 RGPD8 UBE3B RGPD1 ZMIZ1 RNF43 MEFV	1.49e-04	398	58	7	GO:0061659
GeneOntologyMolecularFunction	phosphatidylinositol phosphate binding	ARHGAP32 SNX4 SVIL SNX11 ARAP1	2.79e-04	199	58	5	GO:1901981
GeneOntologyMolecularFunction	angiotensin receptor binding	ZBTB16 ARAP1	3.68e-04	10	58	2	GO:0031701
GeneOntologyMolecularFunction	peptidyl-prolyl cis-trans isomerase activity	RGPD2 RGPD8 RGPD1	4.14e-04	50	58	3	GO:0003755
GeneOntologyMolecularFunction	cis-trans isomerase activity	RGPD2 RGPD8 RGPD1	4.91e-04	53	58	3	GO:0016859
GeneOntologyMolecularFunction	enzyme activator activity	RGPD2 ARHGAP32 RGPD8 PPP1R12B RGPD1 SIPA1L2 ARAP1 RGPD5	5.85e-04	656	58	8	GO:0008047
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RGPD2 ARHGAP32 RGPD8 RGPD1 SIPA1L2 ARAP1 RGPD5	6.40e-04	507	58	7	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RGPD2 ARHGAP32 RGPD8 RGPD1 SIPA1L2 ARAP1 RGPD5	6.40e-04	507	58	7	GO:0030695
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	RGPD2 RGPD8 UBE3B RGPD1 ZMIZ1 RNF43 MEFV	6.79e-04	512	58	7	GO:0019787
GeneOntologyMolecularFunction	aminoacyltransferase activity	RGPD2 RGPD8 UBE3B RGPD1 ZMIZ1 RNF43 MEFV	8.50e-04	532	58	7	GO:0016755
GeneOntologyMolecularFunction	acyltransferase activity	RGPD2 RGPD8 UBE3B RGPD1 ZMIZ1 RNF43 MEFV PDHX	1.71e-03	775	58	8	GO:0016746
GeneOntologyMolecularFunction	phosphatidylinositol binding	ARHGAP32 SNX4 SVIL SNX11 ARAP1	2.22e-03	316	58	5	GO:0035091
GeneOntologyMolecularFunction	isomerase activity	RGPD2 ERCC3 RGPD8 RGPD1	2.34e-03	192	58	4	GO:0016853
GeneOntologyBiologicalProcess	NLS-bearing protein import into nucleus	RGPD2 RGPD8 RGPD1 RGPD5	2.83e-07	20	59	4	GO:0006607
GeneOntologyBiologicalProcess	positive regulation of glucokinase activity	RGPD2 RGPD8 RGPD1	1.84e-06	9	59	3	GO:0033133
GeneOntologyBiologicalProcess	positive regulation of hexokinase activity	RGPD2 RGPD8 RGPD1	2.63e-06	10	59	3	GO:1903301
GeneOntologyBiologicalProcess	regulation of glucokinase activity	RGPD2 RGPD8 RGPD1	6.23e-06	13	59	3	GO:0033131
GeneOntologyBiologicalProcess	regulation of hexokinase activity	RGPD2 RGPD8 RGPD1	7.91e-06	14	59	3	GO:1903299
GeneOntologyBiologicalProcess	protein localization to nucleus	RGPD2 ZBTB16 RGPD8 CALR RGPD1 POM121L2 RGPD5	7.54e-05	362	59	7	GO:0034504
GeneOntologyBiologicalProcess	adrenergic receptor signaling pathway	CRTC3 ADCY9 GSK3A	1.36e-04	35	59	3	GO:0071875
GeneOntologyBiologicalProcess	protein peptidyl-prolyl isomerization	RGPD2 RGPD8 RGPD1	1.75e-04	38	59	3	GO:0000413
GeneOntologyBiologicalProcess	nuclear export	RGPD2 RGPD8 CALR RGPD1 POM121L2	1.86e-04	185	59	5	GO:0051168
GeneOntologyBiologicalProcess	protein import into nucleus	RGPD2 RGPD8 RGPD1 POM121L2 RGPD5	2.37e-04	195	59	5	GO:0006606
GeneOntologyBiologicalProcess	import into nucleus	RGPD2 RGPD8 RGPD1 POM121L2 RGPD5	2.73e-04	201	59	5	GO:0051170
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RGPD2 RGPD8 RGPD1	1.18e-06	8	59	3	GO:1990723
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RGPD2 RGPD8 RGPD1	2.53e-06	10	59	3	GO:0044614
GeneOntologyCellularComponent	annulate lamellae	RGPD2 RGPD8 RGPD1	7.60e-06	14	59	3	GO:0005642
GeneOntologyCellularComponent	nuclear pore	RGPD2 RGPD8 RGPD1 POM121L2 RGPD5	9.70e-06	101	59	5	GO:0005643
GeneOntologyCellularComponent	nuclear pore nuclear basket	RGPD2 RGPD8 RGPD1	1.69e-05	18	59	3	GO:0044615
GeneOntologyCellularComponent	nuclear inclusion body	RGPD2 RGPD8 RGPD1	2.35e-05	20	59	3	GO:0042405
GeneOntologyCellularComponent	SUMO ligase complex	RGPD2 RGPD8 RGPD1	2.74e-05	21	59	3	GO:0106068
GeneOntologyCellularComponent	nuclear envelope	RGPD2 RGPD8 CALR RGPD1 POM121L2 RNF43 RGPD5	9.74e-04	560	59	7	GO:0005635
MousePheno	elevated level of mitotic sister chromatid exchange	RGPD2 RGPD8 RGPD1	2.33e-05	16	50	3	MP:0003701
Domain	Grip	RGPD2 RGPD8 RGPD1 RGPD5	2.35e-08	11	56	4	SM00755
Domain	GRIP	RGPD2 RGPD8 RGPD1 RGPD5	2.35e-08	11	56	4	PF01465
Domain	Ran_BP1	RGPD2 RGPD8 RGPD1 RGPD5	3.52e-08	12	56	4	PF00638
Domain	GRIP_dom	RGPD2 RGPD8 RGPD1 RGPD5	3.52e-08	12	56	4	IPR000237
Domain	GRIP	RGPD2 RGPD8 RGPD1 RGPD5	3.52e-08	12	56	4	PS50913
Domain	RANBD1	RGPD2 RGPD8 RGPD1 RGPD5	3.52e-08	12	56	4	PS50196
Domain	RanBD	RGPD2 RGPD8 RGPD1 RGPD5	5.08e-08	13	56	4	SM00160
Domain	Ran_bind_dom	RGPD2 RGPD8 RGPD1 RGPD5	5.08e-08	13	56	4	IPR000156
Domain	GCC2_Rab_bind	RGPD2 RGPD8 RGPD1	8.86e-07	7	56	3	IPR032023
Domain	Rab_bind	RGPD2 RGPD8 RGPD1	8.86e-07	7	56	3	PF16704
Domain	-	RGPD2 RGPD8 RGPD1	3.02e-06	10	56	3	1.10.220.60
Domain	PH_dom-like	RGPD2 RGPD8 RGPD1 APBA2 GAB3 ARAP1 RGPD5	2.70e-04	426	56	7	IPR011993
Domain	PX	ARHGAP32 SNX4 SNX11	4.27e-04	49	56	3	PF00787
Domain	PX	ARHGAP32 SNX4 SNX11	4.53e-04	50	56	3	PS50195
Domain	-	ARHGAP32 SNX4 SNX11	4.80e-04	51	56	3	3.30.1520.10
Domain	Phox	ARHGAP32 SNX4 SNX11	5.08e-04	52	56	3	IPR001683
Domain	TPR-contain_dom	RGPD2 RGPD8 RGPD1 RGPD5	1.06e-03	150	56	4	IPR013026
Domain	-	RGPD2 RGPD8 RGPD1 APBA2 GAB3 ARAP1	1.09e-03	391	56	6	2.30.29.30
Domain	TPR_REGION	RGPD2 RGPD8 RGPD1 RGPD5	1.51e-03	165	56	4	PS50293
Domain	TPR	RGPD2 RGPD8 RGPD1 RGPD5	1.51e-03	165	56	4	PS50005
Domain	TPR_1	RGPD8 RGPD1 RGPD5	2.49e-03	90	56	3	PF00515
Domain	TPR_1	RGPD8 RGPD1 RGPD5	2.49e-03	90	56	3	IPR001440
Domain	-	FAT1 CALR FAT3	2.91e-03	95	56	3	2.60.120.200
Domain	ConA-like_dom	FAT1 CALR FAT3 MEFV	4.19e-03	219	56	4	IPR013320
Domain	TPR-like_helical_dom	RGPD2 RGPD8 RGPD1 RGPD5	5.22e-03	233	56	4	IPR011990
Domain	EGF_3	FAT1 FAT3 F12 PEAR1	5.38e-03	235	56	4	PS50026
Domain	EGF	FAT1 FAT3 F12 PEAR1	5.38e-03	235	56	4	SM00181
Domain	LAM_G_DOMAIN	FAT1 FAT3	5.79e-03	38	56	2	PS50025
Domain	EGF_CA	FAT1 FAT3 F12	5.86e-03	122	56	3	SM00179
Domain	EGF-like_Ca-bd_dom	FAT1 FAT3 F12	6.13e-03	124	56	3	IPR001881
Domain	Laminin_G_2	FAT1 FAT3	6.40e-03	40	56	2	PF02210
Domain	EGF-like_dom	FAT1 FAT3 F12 PEAR1	6.58e-03	249	56	4	IPR000742
Domain	TPR	RGPD2 RGPD8 RGPD1	6.83e-03	129	56	3	SM00028
Domain	EGF_1	FAT1 FAT3 F12 PEAR1	7.15e-03	255	56	4	PS00022
Domain	TPR_repeat	RGPD2 RGPD8 RGPD1	7.43e-03	133	56	3	IPR019734
Domain	PX	SNX4 SNX11	7.71e-03	44	56	2	SM00312
Domain	LamG	FAT1 FAT3	7.71e-03	44	56	2	SM00282
Domain	EGF-like_CS	FAT1 FAT3 F12 PEAR1	7.75e-03	261	56	4	IPR013032
Domain	EGF_2	FAT1 FAT3 F12 PEAR1	8.17e-03	265	56	4	PS01186
Pathway	REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS	RGPD2 RGPD8 INCENP RGPD1	8.22e-06	51	36	4	MM15151
Pathway	BIOCARTA_RANBP2_PATHWAY	RGPD2 RGPD8 RGPD1	1.22e-05	18	36	3	MM1549
Pathway	REACTOME_AMPLIFICATION_OF_SIGNAL_FROM_THE_KINETOCHORES	RGPD2 RGPD8 INCENP RGPD1	1.18e-04	100	36	4	MM14561
Pathway	REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY	RGPD2 RGPD8 RGPD1	1.42e-04	40	36	3	MM14945
Pathway	REACTOME_MITOTIC_PROMETAPHASE	RGPD2 ALMS1 RGPD8 INCENP RGPD1	1.51e-04	202	36	5	MM15362
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS	RGPD2 RGPD8 RGPD1	1.53e-04	41	36	3	MM15200
Pathway	REACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS	RGPD2 RGPD8 RGPD1	1.64e-04	42	36	3	MM15039
Pathway	REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA	RGPD2 RGPD8 RGPD1	1.76e-04	43	36	3	MM14609
Pathway	REACTOME_MITOTIC_SPINDLE_CHECKPOINT	RGPD2 RGPD8 INCENP RGPD1	2.16e-04	117	36	4	MM15387
Pathway	REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS	RGPD2 RGPD8 RGPD1	2.30e-04	47	36	3	MM14939
Pathway	REACTOME_GENE_SILENCING_BY_RNA	RGPD2 RGPD8 RGPD1	2.60e-04	49	36	3	MM14837
Pathway	REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS	RGPD2 RGPD8 RGPD1	2.76e-04	50	36	3	MM14610
Pathway	REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	RGPD2 RGPD8 INCENP RGPD1	3.14e-04	129	36	4	MM14894
Pathway	REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN	RGPD2 RGPD8 RGPD1	3.66e-04	55	36	3	MM14917
Pathway	REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS	RGPD2 RGPD8 RGPD1	4.29e-04	58	36	3	MM15149
Pathway	REACTOME_SNRNP_ASSEMBLY	RGPD2 RGPD8 RGPD1	4.29e-04	58	36	3	MM14736
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_FORMINS	RGPD2 RGPD8 INCENP RGPD1	4.41e-04	141	36	4	MM15266
Pathway	REACTOME_RHO_GTPASE_EFFECTORS	RGPD2 RGPD8 INCENP PPP1R12B RGPD1	4.60e-04	257	36	5	MM14755
Pathway	REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS	RGPD2 RGPD8 RGPD1	5.99e-04	65	36	3	MM15147
Pathway	REACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE	RGPD2 RGPD8 RGPD1	8.41e-04	73	36	3	MM14948
Pathway	REACTOME_SUMOYLATION	RGPD2 RGPD8 INCENP RGPD1	8.71e-04	169	36	4	MM14919
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	RGPD2 ARHGAP32 RGPD8 INCENP PPP1R12B RGPD1 ARAP1	1.10e-03	649	36	7	MM15690
Pathway	REACTOME_GLUCOSE_METABOLISM	RGPD2 RGPD8 RGPD1	1.18e-03	82	36	3	MM15394
Pathway	REACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS	RGPD2 RGPD8 RGPD1	1.26e-03	84	36	3	MM14929
Pathway	REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM	RGPD2 RGPD8 RGPD1	1.35e-03	86	36	3	MM15413
Pathway	REACTOME_SEPARATION_OF_SISTER_CHROMATIDS	RGPD2 RGPD8 INCENP RGPD1	1.42e-03	193	36	4	MM14890
Pathway	REACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS	RGPD2 RGPD8 RGPD1	1.64e-03	92	36	3	MM14951
Pathway	WP_COMPLEMENT_SYSTEM	CALR C4BPA F12	1.86e-03	96	36	3	M39581
Pubmed	Complex genomic rearrangements lead to novel primate gene function.	RGPD2 RGPD8 RGPD1 RGPD5	2.60e-10	7	59	4	15710750
Pubmed	Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	30944974
Pubmed	Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	38838144
Pubmed	Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	21205196
Pubmed	Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	18949001
Pubmed	Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	25187515
Pubmed	Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	9037092
Pubmed	Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	23536549
Pubmed	Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	8603673
Pubmed	Retina-specifically expressed novel subtypes of bovine cyclophilin.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	7559465
Pubmed	Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	26632511
Pubmed	Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	17372272
Pubmed	Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	24403063
Pubmed	Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	23818861
Pubmed	Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	38657106
Pubmed	Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	11353387
Pubmed	Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	12191015
Pubmed	Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	22821000
Pubmed	Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.	RGPD2 RGPD8 RGPD1	1.62e-07	7	59	3	20682751
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	ARHGAP32 EIF2D SNX4 ZC2HC1A ALMS1 SVIL RGPD1 USP54 SIPA1L2 PDHX GSK3A	1.73e-07	853	59	11	28718761
Pubmed	The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.	RGPD2 RGPD8 RGPD1	2.58e-07	8	59	3	22262462
Pubmed	The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.	RGPD2 RGPD8 RGPD1	2.58e-07	8	59	3	21670213
Pubmed	Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.	RGPD2 RGPD8 RGPD1	2.58e-07	8	59	3	28745977
Pubmed	Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.	RGPD2 RGPD8 RGPD1	2.58e-07	8	59	3	27412403
Pubmed	Mice lacking Ran binding protein 1 are viable and show male infertility.	RGPD2 RGPD8 RGPD1	2.58e-07	8	59	3	21310149
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	ARHGAP32 ALMS1 SVIL APBA2 USP54 SIPA1L2 RNF43	3.18e-07	263	59	7	34702444
Pubmed	The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.	RGPD2 RGPD8 RGPD1	3.87e-07	9	59	3	9733766
Pubmed	Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.	RGPD2 RGPD8 RGPD1	3.87e-07	9	59	3	28100513
Pubmed	Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.	RGPD2 RGPD8 RGPD1	3.87e-07	9	59	3	18394993
Pubmed	Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.	RGPD2 RGPD8 RGPD1	3.87e-07	9	59	3	28877029
Pubmed	The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.	RGPD2 RGPD8 RGPD1	3.87e-07	9	59	3	11553612
Pubmed	Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.	RGPD2 RGPD8 RGPD1	3.87e-07	9	59	3	17887960
Pubmed	The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.	RGPD2 RGPD8 RGPD1	3.87e-07	9	59	3	10601307
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	RGPD2 RGPD8 INCENP CALR PPP1R12B STK26 SVIL RGPD1 C1orf52 CHAMP1 ARAP1 RGPD5	4.50e-07	1155	59	12	20360068
Pubmed	The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.	RGPD2 RGPD8 RGPD1	5.52e-07	10	59	3	27160050
Pubmed	Parkin ubiquitinates and promotes the degradation of RanBP2.	RGPD2 RGPD8 RGPD1	5.52e-07	10	59	3	16332688
Pubmed	Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.	RGPD2 RGPD8 RGPD1	5.52e-07	10	59	3	8857542
Pubmed	Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.	RGPD2 RGPD8 RGPD1	5.52e-07	10	59	3	21859863
Pubmed	An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.	RGPD2 RGPD8 RGPD1	7.58e-07	11	59	3	35771867
Pubmed	RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.	RGPD2 RGPD8 RGPD1	7.58e-07	11	59	3	17069463
Pubmed	T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.	RGPD2 RGPD8 RGPD1	7.58e-07	11	59	3	34110283
Pubmed	Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.	RGPD2 RGPD8 RGPD1	1.31e-06	13	59	3	31427429
Pubmed	Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.	RGPD2 RGPD8 RGPD1	2.08e-06	15	59	3	14697343
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	FAT1 ALMS1 HLA-DRA FAT3 APBA2 USP54 SIPA1L2 CHAMP1 RNF43 PDHX ADCY9	2.41e-06	1116	59	11	31753913
Pubmed	The rs3129882/rs4248166 in HLA-DRA and rs34372695 in SYT11 are not associated with sporadic Parkinson's disease in Central Chinese population.	SYT11 HLA-DRA	2.83e-06	2	59	2	32253955
Pubmed	Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.	RGPD2 RGPD8 RGPD1	6.98e-06	22	59	3	27717094
Pubmed	Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes.	FAT1 FAT3	8.48e-06	3	59	2	15744052
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	RGPD2 RGPD8 RGPD1 CHAMP1	1.43e-05	86	59	4	37253089
Pubmed	Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.	RGPD8 RGPD5	1.69e-05	4	59	2	9480752
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	RGPD2 ARHGAP32 RGPD8 SYT11 KCTD16 RGPD1 APBA2 SIPA1L2 PDHX GSK3A	1.99e-05	1139	59	10	36417873
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	RGPD2 RGPD8 STK26 RGPD1 RGPD5	3.29e-05	215	59	5	35973513
Pubmed	Peering through the pore: nuclear pore complex structure, assembly, and function.	RGPD2 RGPD8 RGPD1	3.75e-05	38	59	3	12791264
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	SNX4 ALMS1 APBA2 RGPD5	5.30e-05	120	59	4	31413325
Pubmed	Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.	FAT1 FAT3	5.91e-05	7	59	2	16059920
Pubmed	Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity.	FAT1 FAT3	5.91e-05	7	59	2	22510986
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ARHGAP32 SNX4 CALR ZNF174 PPP1R12B SVIL PPM1E ADCY9 GSK3A	6.48e-05	1049	59	9	27880917
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RGPD2 ALMS1 RGPD8 RGPD1 ZMIZ1 CHAMP1	7.65e-05	418	59	6	34709266
Pubmed	Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.	RGPD2 RGPD8 RGPD1 CHAMP1	8.37e-05	135	59	4	31077711
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ARHGAP32 CRTC3 ZBTB16 ALMS1 SVIL USP54 SIPA1L2 GSK3A	9.92e-05	861	59	8	36931259
Pubmed	Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia.	PPM1E RNF43	2.54e-04	14	59	2	23620142
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	ALMS1 RGPD1 SIPA1L2 GSK3A	4.45e-04	209	59	4	36779422
Pubmed	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	HLA-DRA ZMIZ1	4.75e-04	19	59	2	19525953
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FAT1 UBE3B DIP2C SNX11 SIPA1L2 RNF43 ADCY9 ARAP1	5.34e-04	1105	59	8	35748872
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	RGPD2 CRTC3 RGPD8 PTCD1 CALR RGPD1 RGPD5	5.51e-04	844	59	7	25963833
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ALMS1 DIP2C ADCY9 ARAP1	5.87e-04	225	59	4	12168954
Pubmed	Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis.	RGPD2 RGPD8 RGPD1	6.48e-04	99	59	3	27746211
Pubmed	Genetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes.	APBA2 TRPM1	8.96e-04	26	59	2	16280085
Pubmed	C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions.	CALR INAVA	9.66e-04	27	59	2	29420262
Pubmed	Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.	SYT11 ADCY9 GSK3A	1.08e-03	118	59	3	19156168
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	EIF2D ERCC3 ZC2HC1A PPP1R12B STK26 SVIL INAVA GSK3A	1.17e-03	1247	59	8	27684187
Pubmed	Identification of host proteins required for HIV infection through a functional genomic screen.	ARHGAP32 CRTC3 ERCC3 RGPD5	1.19e-03	272	59	4	18187620
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RGPD2 ARHGAP32 ZC2HC1A RGPD8 SVIL KCTD16 RGPD1	1.19e-03	963	59	7	28671696
Pubmed	Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion.	SNX4 CALR SGSH STK26 PDHX GSK3A	1.22e-03	704	59	6	32994395
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	ARHGAP32 ALMS1 ZMIZ1	1.42e-03	130	59	3	12421765
Pubmed	Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.	SYT11 SIPA1L2	1.44e-03	33	59	2	25064009
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	ALMS1 RGPD8 CCDC174 C1orf52 USP54 ADCY9	1.50e-03	733	59	6	34672954
Interaction	RGPD1 interactions	RGPD2 RGPD8 RGPD1 GSK3A RGPD5	2.87e-07	49	58	5	int:RGPD1
Interaction	RGPD4 interactions	RGPD2 RGPD8 RGPD1 RGPD5	4.35e-07	22	58	4	int:RGPD4
Interaction	RGPD2 interactions	RGPD2 RGPD8 RGPD1 RGPD5	1.03e-06	27	58	4	int:RGPD2
Interaction	BICD2 interactions	EIF2D SNX4 ZC2HC1A ALMS1 RGPD8 SVIL RGPD1 USP54 RGPD5	3.30e-06	426	58	9	int:BICD2
Interaction	C2CD4B interactions	FAT1 FAT3 SVIL APBA2	7.69e-06	44	58	4	int:C2CD4B
Interaction	RGPD3 interactions	RGPD2 RGPD8 RGPD1 RGPD5	1.00e-05	47	58	4	int:RGPD3
Interaction	NPIPB6 interactions	RGPD8 RGPD1 RGPD5	1.79e-05	18	58	3	int:NPIPB6
Interaction	RGPD8 interactions	RGPD2 RGPD8 RGPD1 RGPD5	6.12e-05	74	58	4	int:RGPD8
Interaction	NEMP1 interactions	RGPD2 RGPD8 ADCY9 RGPD5	1.26e-04	89	58	4	int:NEMP1
Cytoband	1q32.1	EIF2D PPP1R12B INAVA	3.74e-04	108	59	3	1q32.1
Cytoband	Ensembl 112 genes in cytogenetic band chr1q32	EIF2D PPP1R12B C4BPA INAVA	5.40e-04	290	59	4	chr1q32
Cytoband	17q22	PPM1E RNF43	1.48e-03	44	59	2	17q22
Cytoband	2p11.2	RGPD2 RGPD1	3.11e-03	64	59	2	2p11.2
Cytoband	2q13	RGPD8 RGPD5	3.50e-03	68	59	2	2q13
Cytoband	16p13.3	ZNF174 MEFV ADCY9	3.87e-03	244	59	3	16p13.3
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	RGPD2 RGPD8 RGPD1 RGPD5	1.08e-04	115	39	4	769
GeneFamily	Cadherin related	FAT1 FAT3	6.04e-04	17	39	2	24
GeneFamily	Sorting nexins\|PX-BAR domain containing	SNX4 SNX11	1.77e-03	29	39	2	754
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	FNDC1 FAT1 ZC2HC1A PPP1R12B SVIL	6.80e-06	200	59	5	593bf6a7c557437db9a9249a5058a46014179ef6
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FAT3 PPM1E F12 ZNF682	3.78e-05	142	59	4	7b6678a73d04feac12bbc909f2df478215511de0
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FAT3 PPM1E F12 ZNF682	3.78e-05	142	59	4	347f5832a86f4e41752e36e3e737df7ca6f79e90
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175\|Adult / Lineage, Cell type, age group and donor	FAT1 C4BPA ZNF682 RGPD5	4.68e-05	150	59	4	b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CRTC3 FNDC1 PPP1R12B SVIL	6.47e-05	163	59	4	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	C4BPA INAVA USP54 ZNF682	7.61e-05	170	59	4	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	droplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAT3 STK26 KIAA2012 RNF43	8.15e-05	173	59	4	117163c5cd2b7aaa1c0682c8ac44b4249df4d2f8
ToppCell	droplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAT3 STK26 KIAA2012 RNF43	8.15e-05	173	59	4	01df9baeedf30e3a4891738554cdd300394dbb96
ToppCell	10x5'v1-week_17-19-Lymphocytic_NK-T_NK-ILC_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ZBTB16 APBA2 DIP2C RNF43	9.29e-05	179	59	4	d18a520568cf4b031972d3dd7d4d4bd073ac1fea
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT1 KCTD16 INAVA GREB1	9.29e-05	179	59	4	58ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZC2HC1A PPP1R12B ADCY9 PEAR1	1.03e-04	184	59	4	89ae8bf1a6c2d355d279d23a5e24a08d9ec2334e
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZC2HC1A PPP1R12B ADCY9 PEAR1	1.03e-04	184	59	4	34c84ac9a32eaf96f45b79485119cad65905817d
ToppCell	10x5'-GI_small-bowel-Myeloid_Monocytic-Nonclassical_monocytes\|GI_small-bowel / Manually curated celltypes from each tissue	ZC2HC1A SVIL MEFV CD300C	1.08e-04	186	59	4	a16ecf70271894a842925f232009e2623d16947e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ZBTB16 C4BPA USP54 ZNF682	1.10e-04	187	59	4	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	SVIL GAB3 DIP2C USP54	1.15e-04	189	59	4	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	FAT1 SVIL DIP2C USP54	1.17e-04	190	59	4	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	ASK428-Immune-NK_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	ZNF174 STK26 UBE3B APBA2	1.17e-04	190	59	4	d649f7e17c4227787465dfc02037f791ff85378b
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FAT1 SYT11 FAT3 GREB1	1.22e-04	192	59	4	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FAT1 FAT3 GREB1 RNF43	1.27e-04	194	59	4	fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	FNDC1 FAT1 PPP1R12B SVIL	1.29e-04	195	59	4	4dba732c8d8ecf0ed9ece1814dc4060402199ed9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB16 FAT3 PPP1R12B SVIL	1.32e-04	196	59	4	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	FNDC1 FAT1 ZBTB16 KCTD16	1.32e-04	196	59	4	24d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB16 FAT3 PPP1R12B SVIL	1.32e-04	196	59	4	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	Control_saline-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	ARHGAP32 FAT1 USP54 RNF43	1.34e-04	197	59	4	44a59dfb889577b3160a5b13ada1276771a00241
ToppCell	LPS_only-Hematopoietic_Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages\|LPS_only / Treatment groups by lineage, cell group, cell type	HLA-DRA MEFV CD300C ARAP1	1.37e-04	198	59	4	2985c80e656e483866c696fa08c38af90311cd66
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ARHGAP32 FAT1 USP54 RNF43	1.37e-04	198	59	4	285f729140b1df029c24f6ca1d2438470ac51794
ToppCell	LPS_only-Hematopoietic_Myeloid-Monocytes,_Macrophages\|LPS_only / Treatment groups by lineage, cell group, cell type	HLA-DRA MEFV CD300C ARAP1	1.37e-04	198	59	4	5d48539999d7a17f4165f612bf68be26c085e501
ToppCell	Tracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FNDC1 ERCC3 FAT3 KCTD16	1.37e-04	198	59	4	cbb63b255bdc92a557c5db1f08f7766ed9346607
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ZBTB16 DIP2C ADCY9	1.37e-04	198	59	4	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FNDC1 FAT1 PPP1R12B SVIL	1.37e-04	198	59	4	c9c96066c7fa897b583657f0b77ea093920ae9ba
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FNDC1 FAT1 PPP1R12B SVIL	1.40e-04	199	59	4	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ARHGAP32 FAT1 USP54 RNF43	1.42e-04	200	59	4	e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	FNDC1 FAT1 PPP1R12B SVIL	1.42e-04	200	59	4	c5e051f1aac8dda376c342a9932785a23450e073
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	FNDC1 FAT1 PPP1R12B SVIL	1.42e-04	200	59	4	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FNDC1 FAT1 ZC2HC1A PPP1R12B	1.42e-04	200	59	4	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	FNDC1 FAT1 PPP1R12B GAB3	1.42e-04	200	59	4	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FNDC1 FAT1 ZC2HC1A PPP1R12B	1.42e-04	200	59	4	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FNDC1 FAT1 PPP1R12B SVIL	1.42e-04	200	59	4	c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FNDC1 FAT1 ZC2HC1A PPP1R12B	1.42e-04	200	59	4	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FNDC1 FAT1 PPP1R12B SVIL	1.42e-04	200	59	4	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	FNDC1 FAT1 ZC2HC1A PPP1R12B	1.42e-04	200	59	4	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	FNDC1 FAT1 ZC2HC1A PPP1R12B	1.42e-04	200	59	4	02cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FNDC1 FAT1 PPP1R12B SVIL	1.42e-04	200	59	4	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	LPS_only-Mesenchymal_myocytic\|LPS_only / Treatment groups by lineage, cell group, cell type	FNDC1 FAT1 ZC2HC1A PPP1R12B	1.42e-04	200	59	4	8bc9923f82bfb836e2f524204c92050edeae8ca5
Disease	Colorectal Neoplasms	FAT1 CALR PPM1E ZMIZ1 RNF43	2.15e-04	277	58	5	C0009404
Disease	alcohol and nicotine codependence	RGPD2 RGPD1	2.92e-04	13	58	2	EFO_0004776
Disease	ankylosing spondylitis	INAVA ZMIZ1 MEFV	7.74e-04	91	58	3	EFO_0003898
Disease	Squamous cell carcinoma of esophagus	FAT1 CALR FAT3	8.77e-04	95	58	3	C0279626
Disease	multiple sclerosis	ZC2HC1A HLA-DRA SVIL C1orf52 INAVA ZMIZ1	1.08e-03	594	58	6	MONDO_0005301
Disease	breast cancer, lung cancer	POM121L2 ZMIZ1	1.11e-03	25	58	2	MONDO_0007254, MONDO_0008903
Disease	response to angiotensin-converting enzyme inhibitor, response to angiotensin receptor blocker, angioedema	POM121L2 TRPM1	1.20e-03	26	58	2	EFO_0005325, EFO_0005532, EFO_0010735
Disease	glycoprotein measurement	HLA-DRA POM121L2 F12	1.68e-03	119	58	3	EFO_0004555
Disease	peptic ulcer disease	F12 PDHX	1.93e-03	33	58	2	MONDO_0004247
Disease	celiac disease	PPP1R12B INAVA ZMIZ1	1.98e-03	126	58	3	EFO_0001060

Protein segments in the cluster

Peptide	Gene	Start	Entry
ESPRKPVAKWHSLSE	SYT11	416	Q9BT88
PHASWETYPRPTKED	C4BPA	306	P04003
DWKHPRITSFVIPEP	EIF2D	346	P41214
EEIHRKKTVPEEAWP	ALMS1	3436	Q8TCU4
KPKTRTPEERLKWPH	APBA2	301	Q99767
DWERHVVKAPEEPPK	C1orf52	81	Q8N6N3
SKSDPVPPFISREWK	CFAP91	91	Q7Z4T9
PVHTWPSVTRKDSPE	CD300C	156	Q08708
KTPEKEPPLWHAEFT	RGPD5	1636	Q99666
KTPEKEPPLWHAEFT	RGPD8	1636	O14715
LHIEWISKPKPSLEP	FAT1	1341	Q14517
KRHKGWSPESPSAPD	GREB1	311	Q4ZG55
STDDEAHPRKPIPTW	INCENP	831	Q9NQS7
KIPDRFPERKHPWQS	KCTD16	406	Q68DU8
ITERPLHILPWSPKD	PNLIP	36	P16233
PPKPSHLSERRQEEW	GAB3	311	Q8WWW8
EDWKHVEIPKDVGPP	PDHX	136	O00330
HTTLPADWKHRREPP	PEAR1	861	Q5VY43
RPPLKHASLETPWEL	KIAA2012	461	Q0VF49
HRAKTVPVPEKWTTP	MEFV	536	O15553
PWVRQPSAPEKHSRD	ARHGAP32	1951	A7KAX9
KLRKTHDIPCPDLPW	PPM1E	736	Q8WY54
AHPWTKVFKSRTPPE	GSK3A	361	P49840
WFHPRKRPDVITKTD	GLT6D1	36	Q7Z4J2
ELRKTAPTLSPEHWK	CHAMP1	396	Q96JM3
PPWKDEKHPGFRLTS	CRTC3	141	Q6UUV7
KVTWDPPKDATSRPV	FNDC1	56	Q4ZHG4
STARLHIEWIKKPPP	FAT3	1341	Q8TDW7
HIPDPDAKKPEDWDE	CALR	241	P27797
TESKHLSKPPRDWFP	DIP2C	471	Q9Y2E4
LSKPPRDWFPHIKDA	DIP2C	476	Q9Y2E4
AKDAHLSPKRPWKEP	ADCY9	1301	O60503
KHWEFDAPSPLPETT	HLA-DRA	201	P01903
RKDTKPGVPHIREWD	CCDC174	351	Q6PII3
PLKDDHTSRPLWVAP	ERCC3	66	P19447
LPPWRSSDKHPTDII	FBXO16	216	Q8IX29
HPYEKPRKSSEPWSE	INAVA	331	Q3KP66
KTPEKEPPLWHAEFT	RGPD1	1621	P0DJD0
STLSIPPWEAPKEHK	F12	16	P00748
VPPLPEKRAEFVWHK	SNX4	126	O95219
PPSEEKDHLEVWAPV	SNX11	196	Q9Y5W9
PEARPSTGKPKHEWF	SVIL	271	O95425
PEKEPPLWHAEFTKE	RGPD2	1631	P0DJD1
HPEWSFTTVRKKPDP	STK26	321	Q9P289
KAHVRIELKEPPAWP	RNF43	181	Q68DV7
SRHPETKWHGPPSKV	SIPA1L2	1176	Q9P2F8
SRAWEKPPHPACTKD	SMIM17	26	P0DL12
KPPHPACTKDWEAVE	SMIM17	31	P0DL12
AEPLLVSSPEHPKRW	SGSH	291	P51688
TPEWPIKKEKSCHRP	POM121L2	281	Q96KW2
APETSHRPEKEWPIK	ARAP1	1326	Q96P48
GHKPEEIPPDWRIEK	ZBTB16	651	Q05516
HWEKSPLLQEPTPKL	ZNF174	191	Q15697
EPWNVKRHETIAKPP	ZNF682	61	O95780
AILHPEEKPSWKLAR	TRPM1	986	Q7Z4N2
PEPPKKPSNWRRKHE	ZC2HC1A	71	Q96GY0
TPEDHWLRKDLKPSV	UBE3B	611	Q7Z3V4
PAEETPHPWQKFRTK	PTCD1	666	O75127
SWRPVPIKSDLHIKD	ZMIZ1	821	Q9ULJ6
DKKPPRTLPLHSRDW	USP54	541	Q70EL1
KPEEPKDESPSSWRL	PPP1R12B	426	O60237