Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH17 DNAH5 DNAH8 DNAH9 DYNC1H1

3.26e-0918685GO:0008569
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH17 DNAH5 DNAH8 DNAH9 DYNC1H1

3.65e-0828685GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH17 DNAH5 DNAH8 DNAH9 DYNC1H1

1.58e-0737685GO:0045505
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH17 DNAH5 DNAH8 DNAH9 DYNC1H1

4.02e-0670685GO:0003777
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH17 DNAH5 DNAH8 DNAH9 DYNC1H1

5.13e-05118685GO:0003774
GeneOntologyMolecularFunctionnuclear export signal receptor activity

XPO5 XPO6

7.38e-0412682GO:0005049
GeneOntologyMolecularFunctionATP hydrolysis activity

YTHDC2 DDX53 DNAH5 DNAH8 DNAH9 DYNC1H1 HELB

7.42e-04441687GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity

DNAH17 YTHDC2 DDX53 DNAH5 DNAH8 DNAH9 DYNC1H1 HELB

1.11e-03614688GO:0140657
GeneOntologyBiologicalProcessouter dynein arm assembly

NISCH DNAH17 DNAH5 DNAH8

9.10e-0724654GO:0036158
GeneOntologyBiologicalProcessaxonemal dynein complex assembly

NISCH DNAH17 DNAH5 DNAH8

8.33e-0641654GO:0070286
GeneOntologyBiologicalProcesscilium movement

ADCY10 DNAH17 CFAP43 DNAH5 DNAH8 DNAH9 DYNC1H1

1.78e-05261657GO:0003341
GeneOntologyBiologicalProcessaxoneme assembly

NISCH DNAH17 CFAP43 DNAH5 DNAH8

2.41e-05109655GO:0035082
GeneOntologyBiologicalProcessepithelial cilium movement involved in extracellular fluid movement

ADCY10 CFAP43 DNAH5 DNAH9

3.59e-0559654GO:0003351
GeneOntologyBiologicalProcessextracellular transport

ADCY10 CFAP43 DNAH5 DNAH9

4.37e-0562654GO:0006858
GeneOntologyBiologicalProcessmicrotubule bundle formation

NISCH DNAH17 CFAP43 DNAH5 DNAH8

9.43e-05145655GO:0001578
GeneOntologyBiologicalProcessgerm cell development

TDRD7 ADCY10 MFSD14A PRAMEF5 TBPL1 YTHDC2 CFAP43 PRAMEF6

1.32e-04482658GO:0007281
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

TDRD7 ADCY10 MFSD14A PRAMEF5 TBPL1 YTHDC2 CFAP43 PRAMEF6

2.42e-04527658GO:0022412
GeneOntologyBiologicalProcessoocyte development

TDRD7 PRAMEF5 YTHDC2 PRAMEF6

2.70e-0499654GO:0048599
GeneOntologyBiologicalProcessregulation of toll-like receptor signaling pathway

LGR4 BIRC2 LRRC14

2.72e-0440653GO:0034121
GeneOntologyBiologicalProcessoocyte differentiation

TDRD7 PRAMEF5 YTHDC2 PRAMEF6

3.14e-04103654GO:0009994
GeneOntologyBiologicalProcessregulation of pattern recognition receptor signaling pathway

LGR4 BIRC2 LRRC14 PRKDC ZC3HAV1

3.57e-04193655GO:0062207
GeneOntologyCellularComponentouter dynein arm

DNAH17 DNAH5 DNAH8 DNAH9

4.97e-0812684GO:0036157
GeneOntologyCellularComponentdynein complex

DNAH17 DNAH5 DNAH8 DNAH9 DYNC1H1

8.77e-0754685GO:0030286
GeneOntologyCellularComponentaxonemal dynein complex

DNAH17 DNAH5 DNAH8 DNAH9

1.23e-0625684GO:0005858
GeneOntologyCellularComponentmotile cilium

ADCY10 PRAMEF5 DNAH17 CFAP43 DNAH5 DNAH8 DNAH9 PRAMEF6

1.95e-05355688GO:0031514
GeneOntologyCellularComponentmicrotubule associated complex

DNAH17 DNAH5 DNAH8 DNAH9 DYNC1H1

1.79e-04161685GO:0005875
GeneOntologyCellularComponentaxoneme

DNAH17 CFAP43 DNAH5 DNAH8 DNAH9

5.70e-04207685GO:0005930
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

DNAH17 CFAP43 DNAH5 DNAH8 DNAH9 DYNC1H1

5.76e-04317686GO:0032838
GeneOntologyCellularComponentciliary plasm

DNAH17 CFAP43 DNAH5 DNAH8 DNAH9

5.83e-04208685GO:0097014
GeneOntologyCellularComponent9+2 motile cilium

DNAH17 CFAP43 DNAH5 DNAH8 DNAH9

1.07e-03238685GO:0097729
GeneOntologyCellularComponentcytoplasmic region

DNAH17 CFAP43 DNAH5 DNAH8 DNAH9 DYNC1H1

1.12e-03360686GO:0099568
GeneOntologyCellularComponentchromatoid body

TDRD7 SMG1

1.37e-0317682GO:0033391
HumanPhenoAbnormal sperm motility

DNAH17 CFAP43 DNAH5 DNAH8 DNAH9

6.36e-05115205HP:0012206
HumanPhenoAbnormal sperm physiology

DNAH17 CFAP43 DNAH5 DNAH8 DNAH9

6.36e-05115205HP:0034809
DomainDHC_N1

DNAH5 DNAH8 DNAH9 DYNC1H1

1.11e-088684PF08385
DomainDynein_heavy_dom-1

DNAH5 DNAH8 DNAH9 DYNC1H1

1.11e-088684IPR013594
DomainDynein_heavy_chain_D4_dom

DNAH5 DNAH8 DNAH9 DYNC1H1

1.56e-0714684IPR024317
DomainDynein_HC_stalk

DNAH5 DNAH8 DNAH9 DYNC1H1

1.56e-0714684IPR024743
DomainDynein_heavy_dom-2

DNAH5 DNAH8 DNAH9 DYNC1H1

1.56e-0714684IPR013602
DomainDHC_N2

DNAH5 DNAH8 DNAH9 DYNC1H1

1.56e-0714684PF08393
DomainMT

DNAH5 DNAH8 DNAH9 DYNC1H1

1.56e-0714684PF12777
DomainAAA_8

DNAH5 DNAH8 DNAH9 DYNC1H1

1.56e-0714684PF12780
DomainATPase_dyneun-rel_AAA

DNAH5 DNAH8 DNAH9 DYNC1H1

1.56e-0714684IPR011704
DomainAAA_5

DNAH5 DNAH8 DNAH9 DYNC1H1

1.56e-0714684PF07728
DomainDHC_fam

DNAH5 DNAH8 DNAH9 DYNC1H1

2.13e-0715684IPR026983
DomainDynein_heavy_dom

DNAH5 DNAH8 DNAH9 DYNC1H1

2.13e-0715684IPR004273
DomainDynein_heavy

DNAH5 DNAH8 DNAH9 DYNC1H1

2.13e-0715684PF03028
DomainARM-type_fold

SMG1 PPP2R5D XPO5 NOC2L XPO6 PRKDC FMNL2 GCN1

3.11e-05339688IPR016024
DomainFerI

OTOF FER1L6

1.30e-045682SM01202
DomainFerB

OTOF FER1L6

1.30e-045682SM01201
DomainFerlin_B-domain

OTOF FER1L6

1.30e-045682IPR012561
DomainFerlin_C

OTOF FER1L6

1.30e-045682PF16165
DomainFerlin_C

OTOF FER1L6

1.30e-045682IPR032362
DomainFerIin_dom

OTOF FER1L6

1.30e-045682IPR012968
DomainFerI

OTOF FER1L6

1.30e-045682PF08151
DomainFerB

OTOF FER1L6

1.30e-045682PF08150
DomainFATC

SMG1 PRKDC

1.30e-045682PF02260
DomainFAT

SMG1 PRKDC

1.94e-046682PS51189
DomainFATC

SMG1 PRKDC

1.94e-046682PS51190
DomainXpo1

XPO5 XPO6

1.94e-046682PF08389
DomainFATC_dom

SMG1 PRKDC

1.94e-046682IPR003152
DomainPIK_FAT

SMG1 PRKDC

1.94e-046682IPR014009
DomainExportin-1/Importin-b-like

XPO5 XPO6

1.94e-046682IPR013598
DomainFATC

SMG1 PRKDC

1.94e-046682SM01343
DomainBIR

BIRC2 BIRC6

3.61e-048682SM00238
Domain-

BIRC2 BIRC6

3.61e-0486821.10.1170.10
DomainBIR

BIRC2 BIRC6

3.61e-048682PF00653
DomainBIR_REPEAT_2

BIRC2 BIRC6

3.61e-048682PS50143
DomainBIR_rpt

BIRC2 BIRC6

3.61e-048682IPR001370
DomainBIR_REPEAT_1

BIRC2 BIRC6

3.61e-048682PS01282
DomainCadherin_C

PCDHB14 PCDHB10 PCDHB3

4.79e-0442683IPR032455
DomainCadherin_C_2

PCDHB14 PCDHB10 PCDHB3

4.79e-0442683PF16492
Domain-

NLRP12 PRAMEF5 NISCH LGR4 LRRC14 PRAMEF6

1.10e-033216863.80.10.10
DomainTUDOR

TDRD7 TDRD15

1.16e-0314682PF00567
DomainL_dom-like

NLRP12 PRAMEF5 NISCH LGR4 LRRC14 PRAMEF6

1.23e-03328686IPR032675
DomainPI3/4_kinase_CS

SMG1 PRKDC

1.33e-0315682IPR018936
Domain-

ADCY10 NLRP12 YTHDC2 DDX53 DNAH5 DNAH8 DNAH9 DYNC1H1 HELB

1.47e-037466893.40.50.300
DomainWAP

WFDC13 WFDC8

1.52e-0316682SM00217
Domain-

SMG1 PRKDC

1.52e-03166821.10.1070.11
DomainIBN_N

XPO5 XPO6

1.52e-0316682SM00913
DomainPI3Kc

SMG1 PRKDC

1.52e-0316682SM00146
DomainImportin-beta_N

XPO5 XPO6

1.71e-0317682IPR001494
Domain-

WFDC13 WFDC8

1.71e-03176824.10.75.10
DomainCadherin_2

PCDHB14 PCDHB10 PCDHB3

1.72e-0365683PF08266
DomainCadherin_N

PCDHB14 PCDHB10 PCDHB3

1.72e-0365683IPR013164
DomainAAA+_ATPase

DNAH5 DNAH8 DNAH9 DYNC1H1

1.88e-03144684IPR003593
DomainAAA

DNAH5 DNAH8 DNAH9 DYNC1H1

1.88e-03144684SM00382
DomainPI3/4_kinase_cat_dom

SMG1 PRKDC

1.92e-0318682IPR000403
DomainPI3_PI4_kinase

SMG1 PRKDC

1.92e-0318682PF00454
DomainPI3_4_KINASE_3

SMG1 PRKDC

1.92e-0318682PS50290
DomainPI3_4_KINASE_1

SMG1 PRKDC

1.92e-0318682PS00915
DomainPI3_4_KINASE_2

SMG1 PRKDC

1.92e-0318682PS00916
DomainHEAT_REPEAT

SMG1 PRKDC GCN1

2.12e-0370683PS50077
DomainPRAME_family

PRAMEF5 PRAMEF6

2.15e-0319682IPR026271
DomainWAP_dom

WFDC13 WFDC8

2.88e-0322682IPR008197
DomainARM-like

SMG1 XPO5 XPO6 PRKDC GCN1

3.02e-03270685IPR011989
DomainTUDOR

TDRD7 TDRD15

3.15e-0323682PS50304
DomainP-loop_NTPase

ADCY10 NLRP12 YTHDC2 DDX53 DNAH5 DNAH8 DNAH9 DYNC1H1 HELB

3.50e-03848689IPR027417
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH17 DNAH5 DNAH8 DNAH9

1.14e-0627424M47755
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH17 DNAH5 DNAH8 DNAH9

7.72e-0643424M47669
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH17 DNAH5 DNAH8 DNAH9

9.28e-0645424M47670
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH17 DNAH5 DNAH8 DNAH9

5.24e-10770431178125
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH17 DNAH5 DNAH8 DYNC1H1

1.48e-08147049373155
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

SMG1 XPO5 NOC2L FASTKD1 YTHDC2 PRKDC SSRP1 GCN1 DYNC1H1 RPL7A ZC3HAV1

6.11e-07807701122681889
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

XPO5 NOC2L PRMT5 YTHDC2 PRKDC BIRC6 GCN1 DYNC1H1 RPL7A ZC3HAV1

7.32e-07653701022586326
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

CDK5RAP3 TBPL1 YTHDC2 PRKDC SSRP1 DNAH5 BIRC6 GCN1 DNAH8 DYNC1H1

1.44e-06704701029955894
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

CDK5RAP3 PPP2R5D XPO5 YTHDC2 PRKDC ARHGAP39 GCN1 DYNC1H1 RPL7A ZC3HAV1

1.52e-06708701039231216
Pubmed

Protocadherins.

PCDHB14 PCDHB10 PCDHB3

2.20e-061370312231349
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

DNAH5 DNAH8 DNAH9 DYNC1H1

2.51e-06477048812413
Pubmed

MLF2 Negatively Regulates P53 and Promotes Colorectal Carcinogenesis.

PRMT5 SSRP1 GCN1 RPL7A

2.74e-064870437438558
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

TDRD15 STON1 LGR4 PRKDC FMNL2 BIRC6 GCN1 DYNC1H1 RPL7A ZC3HAV1

3.46e-06777701035844135
Pubmed

STAT4 isoforms differentially regulate Th1 cytokine production and the severity of inflammatory bowel disease.

PRKDC STAT4

3.99e-06270218802110
Pubmed

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.

NOC2L PRKDC GCN1 DYNC1H1 RPL7A ZC3HAV1

5.74e-0622170629991511
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

OTOF OVCH1 DNAH5 RPL7A FER1L6 ZC3HAV1

7.96e-0623470636243803
Pubmed

The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

PCDHB14 PCDHB10 PCDHB3

8.69e-062070311322959
Pubmed

A crucial role for T-bet in selectin ligand expression in T helper 1 (Th1) cells.

ST3GAL4 STAT4

1.20e-05370216099875
Pubmed

Mislocalization of DNAH5 and DNAH9 in respiratory cells from patients with primary ciliary dyskinesia.

DNAH5 DNAH9

1.20e-05370215750039
Pubmed

Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients.

DNAH5 DNAH9

1.20e-05370215845866
Pubmed

Role of STAT4 and STAT6 signaling in allograft rejection and CTLA4-Ig-mediated tolerance.

PRKDC STAT4

1.20e-05370211067913
Pubmed

Islet antigen-specific Th17 cells can induce TNF-α-dependent autoimmune diabetes.

PRKDC STAT4

1.20e-05370224446517
Pubmed

Fyn Regulates Binding Partners of Cyclic-AMP Dependent Protein Kinase A.

XPO5 PRKDC GCN1 DYNC1H1

2.34e-058270430274258
Pubmed

IAPs: more than just inhibitors of apoptosis proteins.

BIRC2 BIRC6

2.39e-05470218414036
Pubmed

Binding of microtubule-associated protein 1B to LIS1 affects the interaction between dynein and LIS1.

DNAH8 DYNC1H1

2.39e-05470215762842
Pubmed

DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm.

DNAH5 DNAH9

2.39e-05470218950741
Pubmed

Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.

NLRP12 PRAMEF5 PRAMEF6

2.47e-052870325089626
Pubmed

Evidence that the transcriptional repressor ICER is regulated via the N-end rule for ubiquitination.

PRKDC GCN1 DYNC1H1

2.47e-052870335227662
Pubmed

Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation.

XPO5 PRKDC SSRP1 BIRC6 ZC3HAV1

3.24e-0518070530110629
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

SACS NOC2L PRMT5 YTHDC2 PRKDC RB1CC1 SSRP1 GCN1 DYNC1H1 RPL7A

3.75e-051024701024711643
Pubmed

Monomerization of cytosolic mature smac attenuates interaction with IAPs and potentiation of caspase activation.

BIRC2 BIRC6

3.98e-05570220957035
Pubmed

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

DNAH5 DNAH9

3.98e-05570226909801
Pubmed

ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry.

DNAH5 DNAH9

3.98e-05570223849778
Pubmed

The establishment of rotational polarity in the airway and ependymal cilia: analysis with a novel cilium motility mutant mouse.

DNAH5 DNAH9

3.98e-05570223525783
Pubmed

Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry.

PRKDC GCN1 DYNC1H1

4.47e-053470311101529
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

NOC2L PRMT5 RB1CC1 SSRP1 BIRC6 GCN1 HELB

4.47e-0546970727634302
Pubmed

Interactome of the Autoimmune Risk Protein ANKRD55.

PRMT5 PRKDC GCN1 DYNC1H1 RPL7A

4.98e-0519770531620119
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

NOC2L YTHDC2 PRKDC SSRP1 DYNC1H1 RPL7A ZC3HAV1

5.38e-0548370736912080
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

FRMPD4 XPO6 DNAH9 DYNC1H1

5.94e-051047049205841
Pubmed

CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.

DNAH5 DNAH9

5.96e-05670233347437
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

PPP2R5D CEP120 XPO5 XPO6 NISCH MKLN1 SSRP1 FMNL2 GCN1 DYNC1H1 ZC3HAV1

6.30e-051321701127173435
Pubmed

Nuclear organization of nucleotide excision repair is mediated by RING1B dependent H2A-ubiquitylation.

NOC2L PRMT5 PRKDC RPL7A

7.93e-0511270428416769
Pubmed

The inhibitors of apoptosis (IAPs) and their emerging role in cancer.

BIRC2 BIRC6

8.33e-0577029916987
Pubmed

IAP family proteins--suppressors of apoptosis.

BIRC2 BIRC6

8.33e-0577029990849
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH5 DNAH8

8.33e-0577029256245
Pubmed

The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development.

BIRC2 BIRC6

8.33e-05770215640352
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

SMG1 XPO5 XPO6 BIRC6 GCN1

9.32e-0522570512168954
Pubmed

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.

XPO5 PRKDC GCN1 DYNC1H1

9.71e-0511870427377895
Pubmed

A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.

SMG1 PRKDC

1.11e-04870220810650
Pubmed

CFAP43 modulates ciliary beating in mouse and Xenopus.

CFAP43 DNAH9

1.11e-04870231884020
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

PRMT5 PCDHB14 ST3GAL4 PRKDC FMNL2 BIRC6 TMEM132B DYNC1H1

1.15e-0473670829676528
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

XPO5 NOC2L PRMT5 YTHDC2 PRKDC SSRP1 DNAH5 GCN1 DYNC1H1 RPL7A ZC3HAV1

1.23e-041425701130948266
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

NOC2L YTHDC2 PRKDC SSRP1 BIRC6 GCN1 RPL7A ZC3HAV1

1.42e-0475970835915203
Pubmed

Transport of the outer dynein arm complex to cilia requires a cytoplasmic protein Lrrc6.

DNAH5 DNAH9

1.42e-04970227353389
Pubmed

SIK2 orchestrates actin-dependent host response upon Salmonella infection.

SMG1 YTHDC2 FMNL2

1.43e-045070333947818
Pubmed

The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.

PRMT5 MKLN1 PRKDC BIRC6 ZC3HAV1

1.61e-0425370529911972
Pubmed

Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.

PRMT5 PRKDC RB1CC1 DYNC1H1 RPL7A

1.70e-0425670532698014
Pubmed

Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members.

TDRD7 PRMT5

1.78e-041070219584108
Pubmed

ZMYND10 functions in a chaperone relay during axonemal dynein assembly.

DNAH17 DNAH5

1.78e-041070229916806
Pubmed

Tel2 regulates the stability of PI3K-related protein kinases.

SMG1 PRKDC

1.78e-041070218160036
Pubmed

Reproduction and immunity-driven natural selection in the human WFDC locus.

WFDC13 WFDC8

1.78e-041070223292442
Pubmed

Dependence of leucine-rich repeat kinase 2 (LRRK2) kinase activity on dimerization.

PRKDC DYNC1H1

1.78e-041070219826009
Pubmed

UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.

SMG1 NOC2L PRKDC RPL7A ZC3HAV1

2.07e-0426770533417871
Pubmed

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.

XPO5 PRMT5 PRKDC GCN1 DYNC1H1 RPL7A

2.10e-0442270627342126
Pubmed

ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.

PRKDC SSRP1 GCN1 DYNC1H1 ZC3HAV1

2.11e-0426870533024031
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

PCDHB14 PCDHB10 PCDHB3

2.11e-045770332633719
Pubmed

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.

SMG1 PRKDC

2.17e-041170220427287
Pubmed

FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16.

PRKDC SSRP1

2.17e-041170218406329
Pubmed

RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.

PRMT5 PRKDC GCN1 DYNC1H1 RPL7A ZC3HAV1

2.18e-0442570621081503
Pubmed

CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.

PCDHB14 PCDHB10 PCDHB3

2.23e-045870330377227
Pubmed

Repression of rRNA transcription by PARIS contributes to Parkinson's disease.

NOC2L PRKDC GCN1 DYNC1H1 RPL7A

2.25e-0427270525315684
Pubmed

Characterization of the pVHL Interactome in Human Testis Using High-Throughput Library Screening.

TDRD7 CDK5RAP3 NISCH

2.58e-046170335205757
Pubmed

Concordant and opposite roles of DNA-PK and the "facilitator of chromatin transcription" (FACT) in DNA repair, apoptosis and necrosis after cisplatin.

PRKDC SSRP1

2.60e-041270221679440
Pubmed

Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.

PPP2R5D PRKDC

2.60e-041270216541024
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

SMG1 NOC2L NISCH YTHDC2 SSRP1 ZC3HAV1

2.62e-0444070634244565
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

XPO5 NOC2L TBPL1 PRMT5 PRKDC SSRP1 GCN1 DYNC1H1 RPL7A ZC3HAV1

2.96e-041318701030463901
Pubmed

Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex.

PRKDC GCN1 DYNC1H1

2.98e-046470322865885
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

XPO5 PRKDC SSRP1 GCN1 DYNC1H1 RPL7A ZC3HAV1

2.98e-0463870733239621
Pubmed

Prominin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium.

DNAH5 DNAH9

3.07e-041370235942101
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

XPO5 PRMT5 PRKDC SSRP1 BIRC6 GCN1 ZC3HAV1

3.56e-0465770736180527
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHB14 PCDHB10 PCDHB3

3.56e-046870311230163
Pubmed

UHRF2 commissions the completion of DNA demethylation through allosteric activation by 5hmC and K33-linked ubiquitination of XRCC1.

PRKDC SSRP1

3.58e-041470234111398
Pubmed

A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein.

WFDC13 WFDC8

3.58e-041470212206714
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SLC12A4 XPO6 NISCH LRRC14 PRKDC CFAP43 BIRC6 GCN1 DYNC1H1

3.65e-04110570935748872
Pubmed

IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.

PRKDC DYNC1H1

4.12e-041570218303054
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHB14 PCDHB10 PCDHB3

4.22e-047270310380929
Pubmed

DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.

PRMT5 PRKDC GCN1 DYNC1H1

4.38e-0417570425756610
Pubmed

Drafting the CLN3 protein interactome in SH-SY5Y human neuroblastoma cells: a label-free quantitative proteomics approach.

XPO5 PRKDC GCN1

4.39e-047370323464991
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

YTHDC2 PRKDC SSRP1 FMNL2 RPL7A ZC3HAV1

4.45e-0448670630940648
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHB14 PCDHB10 PCDHB3

4.57e-047470310817752
Pubmed

Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment.

XPO5 PRKDC SSRP1 GCN1 DYNC1H1 RPL7A

4.69e-0449170622623428
Pubmed

The evolution of a genetic locus encoding small serine proteinase inhibitors.

WFDC13 WFDC8

4.71e-041670215950183
Pubmed

Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?

TDRD7 PRMT5

4.71e-041670216787967
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SACS DNAH17 LRRC14 ARHGAP39 FMNL2 BIRC6

4.79e-0449370615368895
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

XPO5 PRMT5 NISCH PRKDC SSRP1 GCN1 DYNC1H1 RPL7A ZC3HAV1

4.84e-04114970935446349
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

SACS PRKDC DYNC1H1

4.94e-047670327542412
Pubmed

Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event.

PRMT5 PRKDC SSRP1 RPL7A

5.08e-0418270426527279
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHB14 PCDHB10 PCDHB3

5.13e-047770310835267
Pubmed

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.

XPO5 XPO6 PRKDC GCN1

5.19e-0418370423956138
Pubmed

Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.

PRAMEF5 PRAMEF6

5.33e-041770223565261
Pubmed

Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.

PRAMEF5 PRAMEF6

5.33e-041770237781892
Pubmed

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.

XPO5 PRMT5 PRKDC SSRP1 GCN1 DYNC1H1 RPL7A

5.51e-0470770719738201
Pubmed

NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.

PRMT5 PRKDC DNAH9 DYNC1H1 RPL7A

5.68e-0433370532665550
Cytoband8q11

PRKDC RB1CC1

3.42e-0567028q11
Cytoband1p36.21

PRAMEF5 AADACL4 PRAMEF6

1.26e-04637031p36.21
Cytoband5q31

PCDHB14 PCDHB10 PCDHB3

7.42e-041157035q31
GeneFamilyDyneins, axonemal

DNAH17 DNAH5 DNAH8 DNAH9

7.78e-0817454536
GeneFamilyFerlin family

OTOF FER1L6

9.03e-056452828
GeneFamilyExportins

XPO5 XPO6

1.26e-047452547
GeneFamilyRing finger proteins|Baculoviral IAP repeat containing|Caspase recruitment domain containing

BIRC2 BIRC6

1.68e-048452419
GeneFamilyClustered protocadherins

PCDHB14 PCDHB10 PCDHB3

5.40e-046445320
GeneFamilyWAP four-disulfide core domain containing|Fibronectin type III domain containing

WFDC13 WFDC8

9.04e-0418452361
GeneFamilyPRAME family

PRAMEF5 PRAMEF6

1.61e-0324452686
GeneFamilyTudor domain containing

TDRD7 TDRD15

3.82e-0337452780
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

SACS NOC2L RB1CC1

1.03e-02181453694
CoexpressionWIERENGA_PML_INTERACTOME

PRKDC DNAH5 GCN1 FER1L6

4.83e-0642704M2219
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SMG1 RB1CC1 BIRC6 DYNC1H1 STAT4 ZC3HAV1

5.16e-07188706ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADCY10 FRMPD4 HEPHL1 DNAH9 UNC5D

5.70e-06162705bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SMG1 YTHDC2 STAT4 HELB ZC3HAV1

7.41e-061717052e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP43 ARHGAP39 DNAH5 DNAH9 MAP3K19

7.84e-06173705c3762655caa79ac4879876f470d32578a3c93b01
ToppCell15-Airway-Epithelial-Multiciliated_precursor|Airway / Age, Tissue, Lineage and Cell class

DNAH17 CFAP43 DNAH5 DNAH9 MAP3K19

9.00e-06178705d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFN1 FRMPD4 DNAH5 DNAH9 UNC5D

1.06e-05184705ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFN1 FRMPD4 DNAH5 DNAH9 UNC5D

1.06e-051847052cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFN1 FRMPD4 DNAH5 DNAH9 UNC5D

1.06e-051847052b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP43 ARHGAP39 DNAH5 DNAH9 MAP3K19

1.09e-051857055e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TDRD15 NLRP12 ARHGAP39 MAP3K19

3.61e-05118704c351e465ece4f3767b2c19e695eca3c263c68777
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WFDC13 NLRP12 IGFN1 DNAH9

7.22e-051417044aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WFDC13 NLRP12 IGFN1 DNAH9

7.22e-05141704e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellCOVID-19-kidney-Technical/muscle|kidney / Disease (COVID-19 only), tissue and cell type

DDX53 DNAH8 TMEM132B DNAH9

8.71e-051487040dbd87078f54ee1c2f8ec64e8bac9dfddb9c181e
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Thalamus / BrainAtlas - Mouse McCarroll V32

ADCY10 OTOF IL1RAPL2 UNC5D

8.71e-05148704afebb64365c94b9476494bffe7c364677f19c8cf
ToppCellThalamus-Neuronal-Inhibitory|Thalamus / BrainAtlas - Mouse McCarroll V32

ADCY10 OTOF IL1RAPL2 UNC5D

8.71e-051487045f82e5ecacfd223020b8ee975c17d68c1fe6db38
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related-Oligodendrocyte/OPC|GW10 / Sample Type, Dataset, Time_group, and Cell type.

OTOF PCDHB14 DNAH5 AGBL3

9.41e-051517044533bccc996395f74b16af939ce79b6fe253c073
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related|GW10 / Sample Type, Dataset, Time_group, and Cell type.

OTOF PCDHB14 DNAH5 AGBL3

9.41e-05151704edb2f59789c295838d2030b80c792cbea25eaa3d
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP43 DNAH5 DNAH9 MAP3K19

1.02e-041547047556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP43 DNAH5 DNAH9 MAP3K19

1.02e-041547044e3bc24043144143842627cacf6f90dda2228910
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP43 DNAH5 DNAH9 MAP3K19

1.04e-041557045f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP43 DNAH5 DNAH9 MAP3K19

1.04e-041557040944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Agmat|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IGFN1 OTOF UNC5D STAT4

1.07e-0415670409e0702400570089d9012dcf94dfb4827c97e49d
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

SMG1 STAT4 HELB ZC3HAV1

1.07e-041567041545169694f686d28648a68b552c2ae606599d66
ToppCellfacs-Lung-24m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SACS PRMT5 STAT4 ZC3HAV1

1.09e-0415770434eb1cbdb023d3e23b2e1695c9c327c21ef1c870
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SACS PRMT5 STAT4 ZC3HAV1

1.09e-04157704af110085dad5d26b0b7068a78f104ba784fa8564
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SACS PRMT5 STAT4 ZC3HAV1

1.09e-04157704071f10d749b590b75a07ab3c7b00956dc7cda4da
ToppCellfacs-Lung-24m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SACS PRMT5 STAT4 ZC3HAV1

1.09e-04157704fc0c222124f59c94d60335f849554eaa4062f8c7
ToppCellfacs-Lung-24m-Hematologic-Lymphocytic_NK_ILC|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SACS PRMT5 STAT4 ZC3HAV1

1.09e-0415770440b08ace1d9ea7951886f5fed76ac57e9175436b
ToppCellCiliated_cells-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CFAP43 DNAH5 DNAH9 MAP3K19

1.29e-04164704fd30c55d0d75ef8b9396435d836187168095152b
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MFSD14A ST3GAL4 KMO MAP3K19

1.32e-04165704479962ce1c3d6636ae62b6709635299748653801
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

CFAP43 DNAH5 DNAH9 MAP3K19

1.39e-0416770426cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell15-Distal-Epithelial-Multiciliated_precursor|Distal / Age, Tissue, Lineage and Cell class

CFAP43 DNAH5 DNAH9 MAP3K19

1.39e-04167704442ea71a581ed5a547a214132b9f1b0243fd0895
ToppCell15-Distal-Epithelial-Multiciliated_cell|Distal / Age, Tissue, Lineage and Cell class

CFAP43 DNAH5 DNAH9 MAP3K19

1.45e-04169704425d89ab69e9f9eb3df84056676423e390cc6ab1
ToppCellCiliated_cells-A-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CFAP43 DNAH5 FER1L6 MAP3K19

1.49e-041707048b7ef1464ea589886b575ebad5447b085cbdcdba
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

CFAP43 DNAH5 DNAH9 MAP3K19

1.52e-0417170474be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Igfbp4-Inhibitory_Neuron.Gad1Gad2.Igfbp4.Adora1_(Striatum,_interneuron)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ADCY10 KMO FER1L6

1.54e-0466703d6b202d9f5bebaac23b34b689ad306549dec0593
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Igfbp4-Inhibitory_Neuron.Gad1Gad2.Igfbp4.Adora1_(Striatum,_interneuron)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ADCY10 KMO FER1L6

1.54e-04667034a714cf035b22da103054098f85f9170c56e9e83
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Deuterosomal|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

DNAH17 DNAH5 DNAH9 MAP3K19

1.55e-0417270408ad76412c9cc3504141797b44b88478ced87476
ToppCelldroplet-Fat-Gat-18m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP43 DNAH5 TMEM132B DNAH9

1.59e-04173704a40a52d8041d45dc3bef74fe55945ae07aa018d6
ToppCelldroplet-Fat-Gat-18m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP43 DNAH5 TMEM132B DNAH9

1.59e-04173704f0b4dd1cf41d6ee6abb0e1968b8b39f4fabebcb5
ToppCelldroplet-Fat-Gat-18m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP43 DNAH5 TMEM132B DNAH9

1.59e-04173704f3f67531f72d6d52e19c7f1f2db1ab4026fb70da
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TDRD7 MFSD14A TBPL1 ZC3HAV1

1.66e-0417570497616bb5c127284aa9e67bc336dfcf29e137164b
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP43 DNAH5 DNAH9 MAP3K19

1.70e-04176704dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

TDRD7 DNAH9 VWDE HELB

1.73e-04177704a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP43 DNAH5 DNAH9 MAP3K19

1.77e-04178704de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM67 CFAP43 DNAH5 MAP3K19

1.77e-04178704f02076ece0fa899e620971c887ad4da7f48684ed
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP43 ARHGAP39 DNAH9 MAP3K19

1.77e-041787043b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellChildren_(3_yrs)-Epithelial-basal_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRMPD4 LGR4 DNAH5 VWDE

1.77e-04178704fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM67 CFAP43 DNAH5 MAP3K19

1.77e-041787046178706db4a855d72abc156537604d575624df56
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCDHB3 CFAP43 DNAH5 DNAH9

1.81e-04179704d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCDHB3 CFAP43 DNAH5 DNAH9

1.81e-041797048a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCellfacs-GAT-Fat-3m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WFDC8 DNAH5 TMEM132B DNAH9

1.89e-0418170411cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCellfacs-GAT-Fat-3m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WFDC8 DNAH5 TMEM132B DNAH9

1.89e-04181704e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP43 DNAH5 DNAH9 MAP3K19

1.89e-04181704dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

SMG1 MKLN1 STAT4 ZC3HAV1

1.89e-04181704f2315414e714ac86211546a935660c4be6e85f1b
ToppCellfacs-GAT-Fat-3m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WFDC8 DNAH5 TMEM132B DNAH9

1.89e-041817045ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

CFAP43 DNAH5 DNAH9 MAP3K19

1.93e-04182704fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Deuterosomal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DNAH17 CFAP43 DNAH9 MAP3K19

1.93e-04182704000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCellCiliated_cells-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

CFAP43 DNAH5 DNAH9 MAP3K19

1.93e-04182704e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM67 PCDHB14 WFDC8 DNAH9

1.93e-04182704398ce074a04f6482470b488f1affae4af7d2ec58
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CFAP43 DNAH5 DNAH9 MAP3K19

1.93e-04182704e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|367C / Donor, Lineage, Cell class and subclass (all cells)

CFAP43 DNAH5 DNAH9 MAP3K19

1.97e-04183704b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|367C / Donor, Lineage, Cell class and subclass (all cells)

CFAP43 DNAH5 DNAH9 MAP3K19

1.97e-04183704cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCellCiliated_cells-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP43 DNAH5 DNAH9 MAP3K19

2.01e-0418470407c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

CFAP43 ARHGAP39 DNAH9 MAP3K19

2.05e-0418570430f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP43 DNAH5 DNAH9 MAP3K19

2.05e-041857043e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

CFAP43 DNAH5 DNAH9 MAP3K19

2.05e-0418570418a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP43 DNAH5 DNAH9 MAP3K19

2.05e-04185704f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell15-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

CFAP43 DNAH5 DNAH9 MAP3K19

2.05e-041857040998b6bf44287eebbf39249fff23fc3689e44c4e
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PPP2R5D SLC12A4 PRKDC TRMT5

2.05e-04185704daea170d827226dda6750bf1838ffd82f070c4d4
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP43 DNAH5 DNAH9 MAP3K19

2.10e-0418670476033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell18-Distal-Epithelial-Multiciliated_cell|Distal / Age, Tissue, Lineage and Cell class

CFAP43 DNAH5 DNAH9 MAP3K19

2.14e-041877048d7fa6b2950898e7f283401808378ba2a41b9651
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP43 DNAH5 DNAH9 MAP3K19

2.14e-0418770404dba2ed09ee4180830bdf0191921696697ea234
ToppCelltumor_Lung-Epithelial_cells-tS3|Epithelial_cells / Location, Cell class and cell subclass

CFAP43 DNAH5 DNAH9 MAP3K19

2.14e-041877043cea677279e71fdb9879530dea10a5e6393beacd
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP43 DNAH5 DNAH9 MAP3K19

2.14e-041877049e10ed56090d82589bc457788282f664b70ace4b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH17 LGR4 UNC5D KMO

2.14e-04187704c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell21-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

CFAP43 DNAH5 DNAH9 MAP3K19

2.14e-041877041a2178a195d078d1963947b327c6d0d4f2f48341
ToppCellfacs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP43 DNAH5 DNAH9 MAP3K19

2.14e-04187704805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCellmulticiliated|World / shred by cell class for bronchial biopsy

CFAP43 DNAH5 DNAH9 MAP3K19

2.18e-041887046833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCelltumor_Lung-Epithelial_cells-tS3|tumor_Lung / Location, Cell class and cell subclass

CFAP43 DNAH5 DNAH9 MAP3K19

2.18e-0418870426326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCell21-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

CFAP43 DNAH5 DNAH9 MAP3K19

2.18e-04188704803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell(7)_Epithelial-F_(Ciliated)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CFAP43 DNAH5 DNAH9 MAP3K19

2.18e-041887049a8b9f745eed9f129b6c582f48fbbaaacbebb4b3
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFAP43 DNAH5 DNAH9 MAP3K19

2.23e-04189704a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellCOPD|World / Disease state, Lineage and Cell class

STON1 XPO6 STAT4 ZC3HAV1

2.23e-0418970453577632683686dc493a5a3fdc01887ec5c320f2
ToppCellMulticiliated|World / shred by cell class for nasal brushing

CFAP43 DNAH5 DNAH9 MAP3K19

2.23e-0418970434b110aef839376228c5a403a6b5047a945f472b
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

CFAP43 DNAH5 DNAH9 MAP3K19

2.23e-0418970427329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCiliated|World / shred by cell class for parenchyma

CFAP43 DNAH5 DNAH9 MAP3K19

2.23e-04189704711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCellCiliated_cells-A|World / lung cells shred on cell class, cell subclass, sample id

CFAP43 DNAH5 DNAH9 MAP3K19

2.27e-04190704cd87731aaa7d252424f79cfce9f7931457f17bdf
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP43 DNAH5 DNAH9 MAP3K19

2.27e-041907049ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP43 DNAH5 DNAH9 MAP3K19

2.27e-04190704833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

CFAP43 DNAH5 DNAH9 MAP3K19

2.27e-041907047031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FMNL2 RPL7A KMO STAT4

2.32e-041917045c0c44612b4cdbf89c0f1f219416374a7541f610
ToppCell356C-Epithelial_cells-Epithelial-F_(Ciliated)|356C / Donor, Lineage, Cell class and subclass (all cells)

CFAP43 DNAH5 DNAH9 MAP3K19

2.32e-04191704e314dd8f1a841cab847ae3703bedfe1bc623ac61
ToppCellASK428-Epithelial-Ciliated|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

CFAP43 DNAH5 DNAH9 MAP3K19

2.32e-041917040c4b926a28bc94f3cf4d68a911c0a189f6ff505e
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CFAP43 DNAH5 DNAH9 MAP3K19

2.32e-041917042a8e6d560907e71e9f6e190ca0667da804e25641
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP43 DNAH5 DNAH9 MAP3K19

2.32e-041917042d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP43 DNAH5 DNAH9 MAP3K19

2.32e-04191704e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP43 DNAH5 DNAH9 MAP3K19

2.32e-0419170446c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCell356C-Epithelial_cells-Epithelial-F_(Ciliated)-|356C / Donor, Lineage, Cell class and subclass (all cells)

CFAP43 DNAH5 DNAH9 MAP3K19

2.32e-041917048a5a2188b13ef4bbfd626a42565566708a751c1b
ToppCell356C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CFAP43 DNAH5 DNAH9 MAP3K19

2.32e-04191704dad675251e129254955eac179c84a641a4864586
DrugBiliton

DNAH17 DNAH5 DNAH8 DNAH9 DYNC1H1

1.41e-0741685CID000002974
DrugCHEMBL83995

DNAH9 DYNC1H1

8.79e-062682CID009571169
DrugIC261

DNAH17 DNAH5 DNAH8 DNAH9 DYNC1H1

1.01e-0596685CID000003674
Diseasenischarin measurement

NLRP12 NISCH

6.91e-056642EFO_0801841
Diseasefree cholesterol to total lipids in large VLDL percentage

TDRD15 SLC12A4 ST3GAL4

7.17e-0537643EFO_0022281
Diseasetoll/interleukin-1 receptor domain-containing adapter protein measurement

NLRP12 ST3GAL4

9.66e-057642EFO_0802134
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

OTOF FER1L6

9.66e-057642DOID:11724 (implicated_via_orthology)
Diseasephosphatidylcholine measurement

TDRD15 CEP120 OVCH1 UNC5D DYNC1H1

3.82e-04284645EFO_0010226
DiseaseSitus ambiguus

DNAH5 DNAH9

4.77e-0415642C0266642
Diseasegalectin-3 measurement

NLRP12 ST3GAL4

5.45e-0416642EFO_0008137
Diseasesensorineural hearing loss (implicated_via_orthology)

DNAH17 DNAH9

7.73e-0419642DOID:10003 (implicated_via_orthology)
Diseaseotitis media (implicated_via_orthology)

NISCH DNAH5

1.04e-0322642DOID:10754 (implicated_via_orthology)
DiseaseBell's palsy

NLRP12 CDK5RAP3 DNAH8

1.43e-03102643EFO_0007167
Diseasealopecia

MKLN1 LGR4 ST3GAL4 BIRC6

1.88e-03241644MONDO_0004907

Protein segments in the cluster

PeptideGeneStartEntry
LRDTFVFKVVPMLNP

AGBL3

391

Q8NEM8
IPCVVENFPMKARTV

CFAP43

901

Q8NDM7
DLIPPPVCRFMKITV

BIRC6

1846

Q9NR09
FSKVMEPLFRQLAKC

PPP2R5D

396

Q14738
EKLGICSMPKFIRFL

AADACL4

61

Q5VUY2
IFIIMSLCPFVNIPC

ADCY10

666

Q96PN6
ELMAICLAFFPPTPK

ARHGAP39

806

Q9C0H5
IFLFNKEMILCDRPP

RB1CC1

71

Q8TDY2
DRIPMAPSCKLLFEV

DNAH8

2231

Q96JB1
IMKSVTLIFFPLPAC

LGR4

781

Q9BXB1
RIKNPFLSLAACVMP

GCN1

896

Q92616
MVCYIQENLPFLLKP

PCDHB10

381

Q9UN67
VPCFLTFPKQCRMLL

NOC2L

281

Q9Y3T9
LLTVFFTCAPIPLMK

MFSD14A

106

Q96MC6
MICSIQDNLPFFLKP

PCDHB14

381

Q9Y5E9
DFFLLPAQPMISVKC

KMO

276

O15229
ENLKALFRPCAMVVP

DNAH17

1961

Q9UFH2
LFRPCAMVVPDFELI

DNAH17

1966

Q9UFH2
IPCTMKLPERQPEFF

CEP120

206

Q8N960
MRCLFRISFVPKDPI

FRMPD4

281

Q14CM0
CESPTEQVLPMLRFV

CDK5RAP3

216

Q96JB5
FRPISCEPLIIQMNK

FASTKD1

31

Q53R41
LCMPVFHPRFKREFI

PRMT5

41

O14744
KTLPVDFVECLMRFL

FMNL2

726

Q96PY5
MPRKQPAGCIFLLTF

HEPHL1

1

Q6MZM0
CFRLFLTMEINPKVP

DYNC1H1

4121

Q14204
SREPPLCFKIKNNMV

DDX53

46

Q86TM3
LVQAMPVTVCPKFLV

IGFN1

936

Q86VF2
LKSLFRPCAMVVPDF

DNAH9

1986

Q9NYC9
RVFEVMLPEKLFIPN

SACS

3546

Q9NZJ4
RAIAFSICDLMKKPP

HELB

361

Q8NG08
IINRFGPLPEMVFCK

MAP3K19

1151

Q56UN5
DLASVMKKEFPRCLP

DNAH5

3051

Q8TE73
QVVFTDLFPPLCKRM

OTOF

481

Q9HC10
ARKVPHFFCDIRPVM

OR10J1

181

P30954
VMCSIENNLPFFLKP

PCDHB3

381

Q9Y5E6
EQVIFKEMFPPLCRR

FER1L6

306

Q2WGJ9
APNKEMLCITFQIPA

TRMT5

456

Q32P41
LPCVKMFAFPEAREV

TMEM132B

156

Q14DG7
QFPELLFTPMQAIKC

TDRD15

1066

B5MCY1
IDEQMFPCRFIKIVP

MKLN1

121

Q9UL63
LVVFLPALCRKMGVP

RPL7A

166

P62424
MKPPFLLALVVCSVV

IL1RAPL2

1

Q9NP60
LNIINFPMKPTTFVC

OVCH1

1021

Q7RTY7
FRQIIFPEALRCLMK

SMG1

2861

Q96Q15
PKQIRILNPFFMEIA

ST3GAL4

226

Q11206
QPLVDMFRKLPFQAV

TDRD7

1006

Q8NHU6
CLKDVDLIPPFNRML

HERC2P3

441

Q9BVR0
IKSIFDPPVFPVCML

SLC12A4

296

Q9UP95
RQMFFVISLDPPIKQ

SSRP1

251

Q08945
PRCEFLIRMKGQEFV

BIRC2

331

Q13490
LRPLIKMPCLEAFQA

PRAMEF6

66

Q5VXH4
MLIVKDGQCPLFPFT

WFDC8

146

Q8IUA0
FLILDRPAEMPTKCV

VWDE

66

Q8N2E2
LAVCNMPFEIRLPEF

TBPL1

106

P62380
HQLDFIQMKCRVPPV

TRIM67

501

Q6ZTA4
IIKFVPLDACRFELM

STON1

501

Q9Y6Q2
LFKNSFVVERQPCMP

STAT4

311

Q14765
FGFLMPELCLVLKVR

NISCH

771

Q9Y2I1
LRPLIKMPCLEAFQA

PRAMEF5

66

Q5TYX0
MLRVFVKPLVLFCPP

XPO5

891

Q9HAV4
IALRCKARPAMQIFF

UNC5D

71

Q6UXZ4
MKPVIFLDVFLPRVT

PRKDC

901

P78527
EFMVDRLPTVLFFPC

TXNDC11

756

Q6PKC3
KLLAPVNCPIADFLM

YTHDC2

781

Q9H6S0
TTIKLPPIEFFCVVM

XKR3

226

Q5GH77
VLLLQSDPFFMPEIC

ZC3HAV1

136

Q7Z2W4
VFKPFLPSIIALCME

XPO6

906

Q96QU8
MKPVLPLQFLVVFCL

WFDC13

1

Q8IUB5
LPRELFPLLFKVAFM

LRRC14

26

Q15048
VRDNEPLFTMCFVPL

NLRP12

391

P59046