Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	acetylcholine receptor regulator activity	SPDYE7P SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	2.17e-10	27	63	6	GO:0030548
GeneOntologyMolecularFunction	neurotransmitter receptor regulator activity	SPDYE7P SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	2.76e-10	28	63	6	GO:0099602
GeneOntologyMolecularFunction	kinase binding	MYO5A SPDYE7P SPDYE2 MAML1 PRKAR2B SPDYE21 SPDYE5 SPDYE18 SPDYE2B SIRT1 SPDYE6 HTT SPDYE16	8.35e-06	969	63	13	GO:0019900
GeneOntologyMolecularFunction	protein kinase binding	MYO5A SPDYE7P SPDYE2 MAML1 PRKAR2B SPDYE21 SPDYE5 SPDYE18 SPDYE2B SIRT1 SPDYE6 SPDYE16	1.54e-05	873	63	12	GO:0019901
GeneOntologyMolecularFunction	small GTPase binding	DOCK1 MYO5A RASSF1 HPS6 HACE1 DAPK3 IPO4	6.65e-05	321	63	7	GO:0031267
GeneOntologyMolecularFunction	GTPase binding	DOCK1 MYO5A RASSF1 HPS6 HACE1 DAPK3 IPO4	1.36e-04	360	63	7	GO:0051020
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH9 HTT DNAH1	2.15e-04	37	63	3	GO:0045505
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO5A MYO15A DNAH9 DNAH1	5.27e-04	118	63	4	GO:0003774
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH9 DNAH1	1.45e-03	18	63	2	GO:0008569
GeneOntologyBiologicalProcess	positive regulation of cyclin-dependent protein serine/threonine kinase activity	SPDYE7P SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	8.81e-11	25	61	6	GO:0045737
GeneOntologyBiologicalProcess	positive regulation of cyclin-dependent protein kinase activity	SPDYE7P SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	1.86e-10	28	61	6	GO:1904031
GeneOntologyBiologicalProcess	regulation of cyclin-dependent protein serine/threonine kinase activity	SPDYE7P SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	3.92e-07	96	61	6	GO:0000079
GeneOntologyBiologicalProcess	regulation of cyclin-dependent protein kinase activity	SPDYE7P SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	4.99e-07	100	61	6	GO:1904029
GeneOntologyBiologicalProcess	regulation of protein serine/threonine kinase activity	SPDYE7P SPDYE2 PRKAR2B SPDYE5 SPDYE2B SIRT1 SPDYE6 HTT SPDYE16	1.01e-06	358	61	9	GO:0071900
GeneOntologyBiologicalProcess	positive regulation of protein serine/threonine kinase activity	SPDYE7P SPDYE2 SPDYE5 SPDYE2B SIRT1 SPDYE6 SPDYE16	1.60e-06	193	61	7	GO:0071902
GeneOntologyBiologicalProcess	regulation of cAMP-dependent protein kinase activity	PRKAR2B SIRT1 HTT	1.34e-05	16	61	3	GO:2000479
GeneOntologyBiologicalProcess	regulation of kinase activity	SPDYE7P SPDYE2 NLRC5 PRKAR2B SPDYE5 SPDYE2B SIRT1 SPDYE6 HTT SPDYE16	3.02e-05	686	61	10	GO:0043549
GeneOntologyBiologicalProcess	regulation of protein kinase activity	SPDYE7P SPDYE2 PRKAR2B SPDYE5 SPDYE2B SIRT1 SPDYE6 HTT SPDYE16	7.27e-05	611	61	9	GO:0045859
GeneOntologyBiologicalProcess	positive regulation of protein kinase activity	SPDYE7P SPDYE2 SPDYE5 SPDYE2B SIRT1 SPDYE6 SPDYE16	7.58e-05	350	61	7	GO:0045860
GeneOntologyBiologicalProcess	regulation of transferase activity	SPDYE7P SPDYE2 NLRC5 PRKAR2B SPDYE5 SPDYE2B SIRT1 SPDYE6 HTT SPDYE16	1.21e-04	810	61	10	GO:0051338
GeneOntologyBiologicalProcess	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	MYO5A HTT	1.79e-04	7	61	2	GO:0031585
GeneOntologyBiologicalProcess	positive regulation of kinase activity	SPDYE7P SPDYE2 SPDYE5 SPDYE2B SIRT1 SPDYE6 SPDYE16	1.87e-04	405	61	7	GO:0033674
GeneOntologyBiologicalProcess	positive regulation of molecular function	ORAI1 TBC1D10A SPDYE7P TRIM26 SPDYE2 EIF3C SPDYE5 TBC1D8B SPDYE2B SIRT1 SPDYE6 HTT SPDYE16	2.31e-04	1430	61	13	GO:0044093
GeneOntologyBiologicalProcess	negative regulation of cAMP-dependent protein kinase activity	PRKAR2B SIRT1	2.38e-04	8	61	2	GO:2000480
GeneOntologyBiologicalProcess	citrulline metabolic process	CAD HTT	3.06e-04	9	61	2	GO:0000052
GeneOntologyBiologicalProcess	regulation of protein modification process	BOD1 MTA1 SPDYE7P RASSF1 INSM1 SPDYE2 PRKAR2B SPDYE5 SPDYE2B SIRT1 SPDYE6 HTT SPDYE16	3.41e-04	1488	61	13	GO:0031399
Domain	Spy1	SPDYE2 SPDYE21 SPDYE5 SPDYE2B SPDYE6 SPDYE16	4.30e-13	11	61	6	PF11357
Domain	Speedy	SPDYE2 SPDYE21 SPDYE5 SPDYE2B SPDYE6 SPDYE16	4.30e-13	11	61	6	IPR020984
Domain	Dynein_heavy_chain_D4_dom	DNAH9 DNAH1	9.31e-04	14	61	2	IPR024317
Domain	Dynein_HC_stalk	DNAH9 DNAH1	9.31e-04	14	61	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH9 DNAH1	9.31e-04	14	61	2	IPR013602
Domain	DHC_N2	DNAH9 DNAH1	9.31e-04	14	61	2	PF08393
Domain	MT	DNAH9 DNAH1	9.31e-04	14	61	2	PF12777
Domain	AAA_8	DNAH9 DNAH1	9.31e-04	14	61	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH9 DNAH1	9.31e-04	14	61	2	IPR011704
Domain	AAA_5	DNAH9 DNAH1	9.31e-04	14	61	2	PF07728
Domain	DHC_fam	DNAH9 DNAH1	1.07e-03	15	61	2	IPR026983
Domain	Dynein_heavy_dom	DNAH9 DNAH1	1.07e-03	15	61	2	IPR004273
Domain	Dynein_heavy	DNAH9 DNAH1	1.07e-03	15	61	2	PF03028
Domain	P-loop_NTPase	MYO5A NLRC5 MYO15A NDUFA10 DNAH9 SNRNP200 HYDIN DNAH1	6.11e-03	848	61	8	IPR027417
Domain	Myosin_head_motor_dom	MYO5A MYO15A	6.84e-03	38	61	2	IPR001609
Domain	MYOSIN_MOTOR	MYO5A MYO15A	6.84e-03	38	61	2	PS51456
Domain	Myosin_head	MYO5A MYO15A	6.84e-03	38	61	2	PF00063
Domain	MYSc	MYO5A MYO15A	6.84e-03	38	61	2	SM00242
Pubmed	Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene.	SPDYE7P SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	2.55e-15	9	64	6	36272447
Pubmed	Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.	SPDYE7P SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	5.18e-14	13	64	6	15611625
Pubmed	Characterization of a new family of cyclin-dependent kinase activators.	SPDYE7P SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16	3.72e-13	17	64	6	15574121
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	CAD MTA1 EIF3C SNRNP200 SIRT1	9.54e-06	153	64	5	26365490
Pubmed	Evolution of the Cdk-activator Speedy/RINGO in vertebrates.	SPDYE2 SPDYE6	9.99e-06	3	64	2	22763696
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ORAI1 CAD MTA1 TBC1D10A MYO5A TRIM26 MAML1 ARHGEF12 EIF3C IPO4 NDUFA10 LRCH3	1.59e-05	1497	64	12	31527615
Pubmed	Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.	DNAH9 HYDIN	2.00e-05	4	64	2	36140829
Pubmed	Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway.	SIRT1 HTT	2.00e-05	4	64	2	22179316
Pubmed	[Expression of Twist1, SIRT1, FGF2 and TGF-β3 genes and its regulatory effect on the proliferation of placenta, umbilical cord and dental pulp mesenchymal stem cells].	TGFB3 SIRT1	2.00e-05	4	64	2	33565061
Pubmed	Linkage groups of the theta and Ly-A loci.	MYO5A HPS6	2.00e-05	4	64	2	5279341
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	CAD MTA1 MYO5A TRIM26 IPO4 SNRNP200	2.45e-05	313	64	6	38270169
Pubmed	Metastasis-associated protein 1 is an integral component of the circadian molecular machinery.	MTA1 SIRT1	3.32e-05	5	64	2	24089055
Pubmed	Slate--a new coat color mutant in the mouse.	MYO5A HPS6	3.32e-05	5	64	2	13943454
Pubmed	DNA double-strand breaks lead to activation of hypermethylated in cancer 1 (HIC1) by SUMOylation to regulate DNA repair.	MTA1 SIRT1	3.32e-05	5	64	2	23417673
Pubmed	Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus.	CAPN5 HTT	3.32e-05	5	64	2	14981075
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	DOCK1 CAD MYO5A IPO4 SNRNP200	3.63e-05	202	64	5	33005030
Pubmed	Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage.	DNAH9 HYDIN PCNT	3.73e-05	35	64	3	37890489
Pubmed	Melanoregulin, product of the dsu locus, links the BLOC-pathway and OA1 in organelle biogenesis.	MYO5A HPS6	4.98e-05	6	64	2	22984402
Pubmed	Transcriptional repression by the basic helix-loop-helix protein Dec2: multiple mechanisms through E-box elements.	BHLHE41 SIRT1	4.98e-05	6	64	2	17487425
Pubmed	CCAAT/enhancer binding protein delta (C/EBPdelta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage.	TRIM26 IPO4	6.96e-05	7	64	2	20805509
Pubmed	Integration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity.	SIRT1 HTT	6.96e-05	7	64	2	22956852
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DOCK1 EOGT MYO5A TRIM26 DMAC2 NLRC5 ADGRV1 HTT LRCH3 PCNT DNAH1	7.86e-05	1489	64	11	28611215
Pubmed	BAC/YAC contigs from the H2-M region of mouse Chr 17 define gene order as Znf173-Tctex5-mog-D17Tu42-M3-M2.	TRIM26 MOG	9.27e-05	8	64	2	9510555
Pubmed	CFAP43 modulates ciliary beating in mouse and Xenopus.	DNAH9 DNAH1	9.27e-05	8	64	2	31884020
Pubmed	Normal lytic granule secretion by cytotoxic T lymphocytes deficient in BLOC-1, -2 and -3 and myosins Va, VIIa and XV.	HPS6 MYO15A	9.27e-05	8	64	2	15702992
Pubmed	The Effects of Genotype and Cell Environment on Melanoblast Differentiation in the House Mouse.	MYO5A HPS6	1.19e-04	9	64	2	17247639
Pubmed	HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs.	ORAI1 SIRT1	1.19e-04	9	64	2	21956116
Pubmed	HIV-1 Tat- and Vpr-responsive microRNAs of neuronal cells.	ORAI1 SIRT1	1.19e-04	9	64	2	24489003
Pubmed	The fine structure of melanogenesis in coat color mutants of the mouse.	MYO5A HPS6	1.19e-04	9	64	2	4634048
Pubmed	The DNA sequence of human chromosome 7.	PRKAR2B SPDYE21 SPDYE5 SPDYE2B SPDYE6 SPDYE16	1.62e-04	441	64	6	12853948
Pubmed	The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53.	CAD EIF3C SNRNP200	1.79e-04	59	64	3	32382008
Pubmed	The murine dilute suppressor gene encodes a cell autonomous suppressor.	MYO5A HPS6	1.81e-04	11	64	2	7828830
Pubmed	A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01.	TRIM26 MOG	1.81e-04	11	64	2	20593013
Pubmed	Identification of epilepsy genes in human and mouse.	MYO5A ADGRV1	2.17e-04	12	64	2	11700294
Pubmed	NCOA2 promotes lytic reactivation of Kaposi's sarcoma-associated herpesvirus by enhancing the expression of the master switch protein RTA.	CAD EIF3C SNRNP200	2.98e-04	70	64	3	31751430
Pubmed	Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.	ADGRV1 MYO15A	2.99e-04	14	64	2	26754646
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	DOCK1 CAD MTA1 EIF3C IPO4 SIRT1	3.28e-04	503	64	6	16964243
Pubmed	Interaction of the murine dilute suppressor gene (dsu) with fourteen coat color mutations.	MYO5A HPS6	3.45e-04	15	64	2	2379821
Pubmed	The PIAS-like Coactivator Zmiz1 Is a Direct and Selective Cofactor of Notch1 in T Cell Development and Leukemia.	MAML1 SIRT1	3.45e-04	15	64	2	26522984
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CAD MYO5A PRKAR2B COX15 SMPD4 DZIP1 IPO4 SNRNP200 SIRT1 PCNT	3.65e-04	1487	64	10	33957083
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CAD LRRC24 MYO5A ARHGEF12 PRKAR2B DAPK3 IPO4 PCNT	3.77e-04	963	64	8	28671696
Pubmed	Fyn Regulates Binding Partners of Cyclic-AMP Dependent Protein Kinase A.	CAD PRKAR2B PCNT	4.74e-04	82	64	3	30274258
Pubmed	BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets.	MAML1 SIRT1	5.59e-04	19	64	2	23160044
Pubmed	Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.	PRKAR2B PCNT	6.84e-04	21	64	2	22007132
Pubmed	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	PRKAR2B ADGRV1	6.84e-04	21	64	2	20195266
Pubmed	Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.	CAD MTA1 SNRNP200 SIRT1	7.23e-04	219	64	4	31353912
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CAD TRIM26 MAML1 IPO4 SIRT1 PCNT	7.44e-04	588	64	6	38580884
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	CAD HACE1 EIF3C SNRNP200	7.48e-04	221	64	4	29991511
Pubmed	Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.	MTA1 PRKAR2B PCNT	8.71e-04	101	64	3	26949739
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	DOCK1 CAD EIF3C SNRNP200	9.40e-04	235	64	4	30258100
Pubmed	KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.	CAD IPO4 SNRNP200	9.48e-04	104	64	3	36055981
Pubmed	Comparative analysis of 1196 orthologous mouse and human full-length mRNA and protein sequences.	CYP21A2 HTT	9.73e-04	25	64	2	8889551
Pubmed	Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.	CAD MTA1 TRIM26	1.00e-03	106	64	3	19394292
Pubmed	La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1).	CAD HPS6 SNRNP200	1.11e-03	110	64	3	25940091
Pubmed	Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction.	TGFB3 SOX18	1.14e-03	27	64	2	35894043
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CAD MYO5A ARHGEF12 PRKAR2B DAPK3 EIF3C SNRNP200 MOG LRCH3	1.18e-03	1431	64	9	37142655
Pubmed	Age-dependent effects of Armc5 haploinsufficiency on adrenocortical function.	CYP21A2 PRKAR2B	1.22e-03	28	64	2	28911199
Pubmed	SIRT1 coordinates with the CRL4B complex to regulate pancreatic cancer stem cells to promote tumorigenesis.	MTA1 SIRT1	1.22e-03	28	64	2	34163012
Pubmed	Nuclear Gene-Encoded Leigh Syndrome Spectrum Overview	COX15 NDUFA10	1.40e-03	30	64	2	26425749
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	MYO5A HPS6 IPO4 SNRNP200	1.44e-03	264	64	4	32814769
Pubmed	Primary Ciliary Dyskinesia	HYDIN DNAH1	1.60e-03	32	64	2	20301301
Pubmed	Accessory subunits are integral for assembly and function of human mitochondrial complex I.	DMAC2 NDUFA10	1.60e-03	32	64	2	27626371
Pubmed	Calpain activity is negatively regulated by a KCTD7-Cullin-3 complex via non-degradative ubiquitination.	CAD CAPN5	1.70e-03	33	64	2	36964131
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	MTA1 TRIM26 PRKAR2B IPO4	1.83e-03	282	64	4	23667531
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	SPDYE7P SPDYE21 SPDYE5 SPDYE18 SPDYE16	3.96e-05	271	64	5	chr7q11
Cytoband	Ensembl 112 genes in cytogenetic band chr7q22	SPDYE2 PRKAR2B SPDYE2B SPDYE6	2.56e-04	219	64	4	chr7q22
Cytoband	7q11.23	SPDYE7P SPDYE5 SPDYE18	3.47e-04	97	64	3	7q11.23
Cytoband	7q22.1	SPDYE2 SPDYE2B SPDYE6	5.42e-04	113	64	3	7q22.1
GeneFamily	Speedy/RINGO cell cycle regulator family	SPDYE7P SPDYE2 SPDYE5 SPDYE2B SPDYE6	6.66e-11	12	46	5	756
GeneFamily	Dyneins, axonemal	DNAH9 DNAH1	8.41e-04	17	46	2	536
Coexpression	GSE9037_WT_VS_IRAK4_KO_LPS_1H_STIM_BMDM_UP	TGFB3 CAD DMAC2 SMPD4 APLP1 PCNT	8.66e-06	200	63	6	M5815
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRV1 MYO15A DNAH9 HYDIN DNAH1	5.80e-06	184	62	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRV1 MYO15A DNAH9 HYDIN DNAH1	5.80e-06	184	62	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRV1 MYO15A DNAH9 HYDIN DNAH1	5.80e-06	184	62	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Severe-Lymphoid-NK-Treg\|Severe / Condition, Lineage, Cell class and cell subclass	CAD EOGT KBTBD4 TBC1D10A RASSF1	6.78e-06	190	62	5	e67803bf55a3f8e47a69ff1829c9100f870d7527
Disease	Kartagener Syndrome	DNAH9 HYDIN DNAH1	4.75e-05	35	59	3	C0022521
Disease	Polynesian Bronchiectasis	DNAH9 HYDIN DNAH1	4.75e-05	35	59	3	C4317124
Disease	Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus	DNAH9 HYDIN DNAH1	4.75e-05	35	59	3	C4551906
Disease	Clinically Isolated Syndrome, CNS Demyelinating	SIRT1 MOG	1.09e-04	8	59	2	C2350037
Disease	Demyelinating Diseases	SIRT1 MOG	1.09e-04	8	59	2	C0011303
Disease	Demyelination	SIRT1 MOG	1.09e-04	8	59	2	C0011304
Disease	Primary Ciliary Dyskinesia	DNAH9 HYDIN DNAH1	1.16e-04	47	59	3	C4551720
Disease	Todd Paralysis	SIRT1 MOG	1.40e-04	9	59	2	C0234544
Disease	Experimental Autoimmune Encephalomyelitis	SIRT1 MOG	1.40e-04	9	59	2	C0014072
Disease	Paralysed	SIRT1 MOG	1.40e-04	9	59	2	C0522224
Disease	Nonsyndromic Deafness	TGFB3 ADGRV1 MYO15A	5.80e-04	81	59	3	C3711374
Disease	colorectal health	DOCK1 HACE1 ADGRV1 MOG	7.10e-04	201	59	4	EFO_0008460
Disease	Huntington's disease (is_implicated_in)	SIRT1 HTT	9.68e-04	23	59	2	DOID:12858 (is_implicated_in)
Disease	FEV change measurement, response to zileuton	CYP21A2 C4orf50	1.14e-03	25	59	2	EFO_0005921, EFO_0007676

Protein segments in the cluster

Peptide	Gene	Start	Entry
EHPEAVRQLHREFLR	BHMT	51	Q93088
RLPEEHIPFFLHNNR	EOGT	41	Q5NDL2
PHLQERQLLEHRDFI	BHLHE41	6	Q9C0J9
DIAIHLRAQPNFLLH	ADGRV1	3811	Q8WXG9
ELRPQIQELLHSEHL	APLP1	476	P51693
PDNLQALHTLHLRDR	CAPN5	601	O15484
HHLQNLRRLDISDLP	DMAC2	196	Q9NW81
RVHPEVQRHLEDFRQ	ARHGEF12	471	Q9NZN5
HNFLRILQREEEEHL	RASSF1	306	Q9NS23
PERLELERQHTFALH	MAML1	46	Q92585
LNVRRNHLVHLPEEL	LRCH3	201	Q96II8
HPVQLDLLFRQILHD	MYO15A	2706	Q9UKN7
RLQDQLDHRGDHPLT	ORAI1	281	Q96D31
FLLHHPEIQQRLQEE	CYP21A2	306	P08686
FSQPLHEEIALHRRL	MAP3K6	686	O95382
HRPVNENDILLVHRD	HACE1	546	Q8IYU2
IRHPNIITLHDIFEN	DAPK3	71	O43293
TFLHLPRLQELHLQE	LRRC24	141	Q50LG9
PRFQAELEESHRHQL	PCNT	591	O95613
LRAEIENLHRTFDPH	MOG	186	Q16653
TQHVENLLPREHRVD	MAS1L	361	P35410
NILEHREAPIHLDFD	NLRC5	656	Q86WI3
AHQTDRVLHQFRELP	NDUFA10	321	O95299
QLFLEPELVIPHRQH	SMPD4	526	Q9NXE4
ERRRQVPFHLHINLE	EIF3C	666	Q99613
QEALDFIKRQARHHP	GALNS	211	P34059
IQRKHDPRHLVFIDN	GASK1B	416	Q6UWH4
IEHINPDKVHRDFRL	DNAH1	3746	Q9P2D7
EEDPRLRAQQLHHRV	C4orf50	11	Q6ZRC1
NAIHNHIRLFEPLVI	HTT	1416	P42858
LEPRQLHFDRLLLHR	HYDIN	2936	Q4G0P3
DIHQIRKEFPHLVDR	DOCK1	391	Q14185
LNHIFRPQIERAIHE	BOD1	141	Q96IK1
RLQLRHFNELPHELR	ATG9B	486	Q674R7
HFNELPHELRARLAR	ATG9B	491	Q674R7
LRHQPADLLEFALQH	PRKAR2B	21	P31323
VHLIPLQRHLEALEN	DNAH9	311	Q9NYC9
LPETHQLLQLRRFAH	COX15	251	Q7KZN9
AEFAQHRRLDAHLPL	HPS6	676	Q86YV9
EAFQPHHRELLRLLN	IPO4	151	Q8TEX9
QERHLRLLHAAQVFP	INSM1	456	Q01101
RQHLQFDPQTHDLLL	PCDHB6	71	Q9Y5E3
QLQNTEEFLHLPHRL	KBTBD4	176	Q9NVX7
QILINREPLPHLHFD	SIRT1	461	Q96EB6
HQLRHRELFLSRQLE	MTA1	101	Q13330
VLPEHHEAFNRLLED	SPDYE2B	191	A6NHP3
REIPNFHQIREFLEH	DZIP1	586	Q86YF9
RQQLHRPVAHAFVLE	AQP11	36	Q8NBQ7
RNLIDHERLHNGEKP	ZNF197	691	O14709
FEELIRDHLPQLTEH	TBC1D8B	621	Q0IIM8
VLPEHHEAFNRLLED	SPDYE16	151	A6NNV3
VLPEHHEAFNRLLED	SPDYE18	191	P0DV79
RRVLLVLPEHHEAFN	SPDYE21	186	A0A494C086
VLPEHHEAFNRLLED	SPDYE21	191	A0A494C086
VLPEHHEAFNRLLED	SPDYE2	191	Q495Y8
VLPEHHEAFNRLLED	SPDYE5	191	A6NIY4
VLPEHHEAFNRLLED	SPDYE6	191	P0CI01
LVLPEHHEAFNRLLE	SPDYE7P	46	Q495Y7
HQFLREREEHLLEQL	TRIM26	196	Q12899
DDLLQRLHHNPRRIF	CAD	1726	P27708
ENIPIRHHEDNLLRQ	SNRNP200	1856	O75643
VLPEHHEAFNRLLED	nan	151	A6NJR5
EEAERLRVQHLRDHP	SOX18	136	P35713
LDVIERDLHRQFPFH	TBC1D10A	151	Q9BXI6
VPEVRHFQLNVLRFH	TIGD7	271	Q6NT04
QRIELFQILRPDEHI	TGFB3	166	P10600
HEPAVLHNLRVRFID	MYO5A	81	Q9Y4I1