Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphatidylinositol-3,4-bisphosphate binding	FCHSD2 ANXA8L1 PLEKHA1 ANXA8	1.45e-05	35	85	4	GO:0043325
GeneOntologyBiologicalProcess	embryo development	SUPT20HL1 HOXB5 ZFAT KIDINS220 BASP1 TJP1 NRK BRPF1 AFF3 NR0B1 NFRKB ETS2 LAMA5 SPECC1L IRX1 TNRC6C TCF7L1 NPAT	1.08e-05	1437	82	18	GO:0009790
GeneOntologyBiologicalProcess	negative regulation of phospholipase A2 activity	ANXA8L1 ANXA8	4.67e-05	3	82	2	GO:1900138
GeneOntologyCellularComponent	extracellular matrix of synaptic cleft	LAMA5 SPARCL1	4.77e-05	3	84	2	GO:0098965
GeneOntologyCellularComponent	chromatin	MYCL SUPT20HL1 BNC2 HOXB5 PELP1 BASP1 BAZ2B BRPF1 NR0B1 NFRKB ETS2 IRX1 MUC1 TCF7L1 CASZ1 HOXB13	2.37e-04	1480	84	16	GO:0000785
Domain	AnnexinVIII	ANXA8L1 ANXA8	1.95e-05	2	83	2	IPR009115
Domain	SPOC_C	PHF3 DIDO1	2.89e-04	6	83	2	IPR012921
Domain	SPOC	PHF3 DIDO1	2.89e-04	6	83	2	PF07744
Domain	TFS2M	PHF3 DIDO1	4.04e-04	7	83	2	SM00510
Domain	TFIIS_M	PHF3 DIDO1	4.04e-04	7	83	2	PF07500
Domain	Znf_PHD-finger	BAZ2B PHF3 BRPF1 DIDO1	4.23e-04	79	83	4	IPR019787
Domain	Znf_FYVE_PHD	ZFYVE28 BAZ2B PHF3 BRPF1 DIDO1	5.00e-04	147	83	5	IPR011011
Domain	TFIIS_cen_dom	PHF3 DIDO1	5.37e-04	8	83	2	IPR003618
Domain	-	PHF3 DIDO1	5.37e-04	8	83	2	1.10.472.30
Domain	TFIIS_CENTRAL	PHF3 DIDO1	5.37e-04	8	83	2	PS51321
Domain	PHD	BAZ2B PHF3 BRPF1 DIDO1	6.64e-04	89	83	4	SM00249
Domain	Znf_PHD	BAZ2B PHF3 BRPF1 DIDO1	7.22e-04	91	83	4	IPR001965
Domain	ZF_PHD_2	BAZ2B PHF3 BRPF1 DIDO1	8.49e-04	95	83	4	PS50016
Domain	ZF_PHD_1	BAZ2B PHF3 BRPF1 DIDO1	8.83e-04	96	83	4	PS01359
Domain	ANX	ANXA8L1 ANXA8	1.47e-03	13	83	2	SM00335
Domain	ANNEXIN	ANXA8L1 ANXA8	1.47e-03	13	83	2	PS00223
Domain	Annexin_repeat_CS	ANXA8L1 ANXA8	1.47e-03	13	83	2	IPR018252
Domain	Annexin	ANXA8L1 ANXA8	1.47e-03	13	83	2	PF00191
Domain	Annexin_repeat	ANXA8L1 ANXA8	1.47e-03	13	83	2	IPR018502
Domain	-	ANXA8L1 ANXA8	1.47e-03	13	83	2	1.10.220.10
Domain	Annexin	ANXA8L1 ANXA8	1.72e-03	14	83	2	IPR001464
Domain	SEA	MUC16 MUC1	1.72e-03	14	83	2	SM00200
Domain	-	MUC16 MUC1	1.97e-03	15	83	2	3.30.70.960
Domain	Zinc_finger_PHD-type_CS	PHF3 BRPF1 DIDO1	3.03e-03	65	83	3	IPR019786
Domain	WH2_dom	COBLL1 JMY	3.88e-03	21	83	2	IPR003124
Domain	SEA	MUC16 MUC1	4.25e-03	22	83	2	PF01390
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	KIAA1671 GAPVD1 KIDINS220 ARHGAP23 TJP1 COBLL1 PLEKHA1 TANC1 CTNNA2 MARK2 DENND4C	1.54e-07	565	86	11	25468996
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KIAA1671 CCP110 GAPVD1 TJP1 PHF3 COBLL1 ZBTB21 PLEKHA1 TANC1 PROSER2 MARK2 DNAH7 DENND4C	1.97e-07	861	86	13	36931259
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	KIAA1671 CCP110 HBS1L GAPVD1 KIDINS220 TANC1 DENND4C	9.20e-07	209	86	7	36779422
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KIAA1671 HBS1L GAPVD1 TJP1 PHF3 NFRKB DIDO1 RPRD2 SPECC1L KHSRP	1.07e-06	549	86	10	38280479
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	KIAA1671 AP4E1 GAPVD1 KIDINS220 TJP1 PLEKHA1 TANC1	4.22e-06	263	86	7	34702444
Pubmed	KSRP modulation of GAP-43 mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.	GAP43 KHSRP	6.04e-06	2	86	2	24244461
Pubmed	TaqI polymorphisms at the annexin VIII locus (ANX8).	ANXA8L1 ANXA8	6.04e-06	2	86	2	1364010
Pubmed	Annexin A8 controls leukocyte recruitment to activated endothelial cells via cell surface delivery of CD63.	ANXA8L1 ANXA8	6.04e-06	2	86	2	24769558
Pubmed	Usefulness of tumor markers CA 125 and CA 15.3 at diagnosis and during follow-up in non-Hodgkin's lymphoma: study of 200 patients.	MUC16 MUC1	6.04e-06	2	86	2	16194893
Pubmed	Polymorphisms of MUC16 (CA125) and MUC1 (CA15.3) in relation to ovarian cancer risk and survival.	MUC16 MUC1	6.04e-06	2	86	2	24551091
Pubmed	Cooperative binding promotes demand-driven recruitment of AnxA8 to cholesterol-containing membranes.	ANXA8L1 ANXA8	6.04e-06	2	86	2	29306076
Pubmed	Puerperal mastitis: a reproductive event of importance affecting anti-mucin antibody levels and ovarian cancer risk.	MUC16 MUC1	6.04e-06	2	86	2	23925696
Pubmed	Mucins and Truncated O-Glycans Unveil Phenotypic Discrepancies between Serous Ovarian Cancer Cell Lines and Primary Tumours.	MUC16 MUC1	6.04e-06	2	86	2	30011875
Pubmed	Diagnostic value of serum CA125, CA19-9 and CA15-3 in endometriosis: A meta-analysis.	MUC16 MUC1	6.04e-06	2	86	2	26246541
Pubmed	Different Levels of CEA, CA153 and CA125 in Milk and Benign and Malignant Nipple Discharge.	MUC16 MUC1	6.04e-06	2	86	2	27327081
Pubmed	Bone matrix regulates osteoclast differentiation and annexin A8 gene expression.	ANXA8L1 ANXA8	6.04e-06	2	86	2	21344395
Pubmed	Annexin A8 is up-regulated during mouse mammary gland involution and predicts poor survival in breast cancer.	ANXA8L1 ANXA8	6.04e-06	2	86	2	16203777
Pubmed	Analysis of the discriminative methods for diagnosis of benign and malignant solitary pulmonary nodules based on serum markers.	MUC16 MUC1	6.04e-06	2	86	2	25531720
Pubmed	Expression of mucin antigens (MUC1 and MUC16) as a prognostic factor for mucinous adenocarcinoma of the uterine cervix.	MUC16 MUC1	6.04e-06	2	86	2	20598042
Pubmed	Annexins: linking Ca2+ signalling to membrane dynamics.	ANXA8L1 ANXA8	6.04e-06	2	86	2	15928709
Pubmed	Mucins MUC16 and MUC1 are major carriers of SLe(a) and SLe(x) in borderline and malignant serous ovarian tumors.	MUC16 MUC1	6.04e-06	2	86	2	27003157
Pubmed	Glycan elongation beyond the mucin associated Tn antigen protects tumor cells from immune-mediated killing.	MUC16 MUC1	6.04e-06	2	86	2	24039759
Pubmed	Shared and unique roles of CAP23 and GAP43 in actin regulation, neurite outgrowth, and anatomical plasticity.	GAP43 BASP1	6.04e-06	2	86	2	10871284
Pubmed	Annexins: from structure to function.	ANXA8L1 ANXA8	6.04e-06	2	86	2	11917092
Pubmed	Quantification of MUCIN 1, cell surface associated and MUCIN16, cell surface associated proteins in tears and conjunctival epithelial cells collected from postmenopausal women.	MUC16 MUC1	6.04e-06	2	86	2	23687433
Pubmed	Comparison of the transmembrane mucins MUC1 and MUC16 in epithelial barrier function.	MUC16 MUC1	6.04e-06	2	86	2	24968021
Pubmed	Annexin A8 identifies a subpopulation of transiently quiescent c-kit positive luminal progenitor cells of the ductal mammary epithelium.	ANXA8L1 ANXA8	6.04e-06	2	86	2	25803307
Pubmed	Nipple discharge of CA15-3, CA125, CEA and TSGF as a new biomarker panel for breast cancer.	MUC16 MUC1	6.04e-06	2	86	2	24879526
Pubmed	Detection of glyco-mucin profiles improves specificity of MUC16 and MUC1 biomarkers in ovarian serous tumours.	MUC16 MUC1	6.04e-06	2	86	2	25454345
Pubmed	Racial/ethnic differences in average CA125 and CA15.3 values and its correlates among postmenopausal women in the USA.	MUC16 MUC1	6.04e-06	2	86	2	33462738
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	CCP110 GAPVD1 TJP1 PHF3 NFRKB RPRD2 DCLRE1A TANC1 DENND4C VAT1	1.36e-05	733	86	10	34672954
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	KIAA1671 CCP110 GAPVD1 BASP1 TJP1 PLEKHA1 MARK2 DENND4C	1.52e-05	446	86	8	24255178
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	KIAA1671 HBS1L KIDINS220 PHF3 POLR1C NFRKB LAMA5 DIDO1 TANC1 CTNNA2 SPECC1L MARK2 CASZ1 MPG	1.75e-05	1497	86	14	31527615
Pubmed	Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.	MUC16 MUC1	1.81e-05	3	86	2	23053434
Pubmed	Prognostic significance of CA 125, CD44, and epithelial membrane antigen in renal cell carcinoma.	MUC16 MUC1	1.81e-05	3	86	2	12893366
Pubmed	Clinical evaluation of the simultaneous determination of CA 15-3, CA 125 and sHER2 in breast cancer.	MUC16 MUC1	1.81e-05	3	86	2	17852076
Pubmed	Serum concentrations of CA 125, CA 15-3, CA 19-9 and CEA in normal pregnancy: a longitudinal study.	MUC16 MUC1	1.81e-05	3	86	2	21792548
Pubmed	Specific expression of annexin A8 in adult murine stratified epithelia.	ANXA8L1 ANXA8	1.81e-05	3	86	2	17082908
Pubmed	Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.	MUC16 MUC1	1.81e-05	3	86	2	17592322
Pubmed	The motility-associated proteins GAP-43, MARCKS, and CAP-23 share unique targeting and surface activity-inducing properties.	GAP43 BASP1	1.81e-05	3	86	2	9344590
Pubmed	Immunohistochemical comparison of MUC1, CA125, and Her2Neu in invasive micropapillary carcinoma of the urinary tract and typical invasive urothelial carcinoma with retraction artifact.	MUC16 MUC1	1.81e-05	3	86	2	19270645
Pubmed	GAP43, MARCKS, and CAP23 modulate PI(4,5)P(2) at plasmalemmal rafts, and regulate cell cortex actin dynamics through a common mechanism.	GAP43 BASP1	1.81e-05	3	86	2	10871285
Pubmed	Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.	MUC16 MUC1	1.81e-05	3	86	2	35879412
Pubmed	Association of Preoperative Serum Levels of CEA and CA15-3 with Molecular Subtypes of Breast Cancer.	MUC16 MUC1	1.81e-05	3	86	2	34621407
Pubmed	Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).	MUC16 MUC1	1.81e-05	3	86	2	27483328
Pubmed	Vascular anticoagulant beta: a novel human Ca2+/phospholipid binding protein that inhibits coagulation and phospholipase A2 activity. Its molecular cloning, expression and comparison with VAC-alpha.	ANXA8L1 ANXA8	1.81e-05	3	86	2	2530088
Pubmed	Expression and significance of ER, PR, VEGF, CA15-3, CA125 and CEA in judging the prognosis of breast cancer.	MUC16 MUC1	1.81e-05	3	86	2	23886210
Pubmed	Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.	MUC16 MUC1	1.81e-05	3	86	2	24939955
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	BAZ2B AFF3 ZBTB21 RPRD2 DCLRE1A REV1	1.94e-05	222	86	6	37071664
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	BAZ2B PHF3 BRPF1 ZBTB21 NFRKB DIDO1 CASZ1 MPG NPAT	2.00e-05	608	86	9	36089195
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	GAPVD1 PHF3 BRPF1 ZBTB21 NFRKB DIDO1 PROSER2 MARK2 MN1 MPG	2.17e-05	774	86	10	15302935
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	KIAA1671 AP4E1 GAPVD1 KIDINS220 BASP1 TJP1 MUC16 DCLRE1A SPECC1L DNAH7	2.24e-05	777	86	10	35844135
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	XIRP1 ZFAT PHF3 TBC1D8B DNAH7 CASZ1	2.55e-05	233	86	6	37704626
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PRUNE2 CCP110 HBS1L CMTR1 ARHGAP23 BAZ2B COBLL1 CASZ1	3.11e-05	493	86	8	15368895
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	CCP110 PHF3 COBLL1 DIDO1 RPRD2 MARK2 DENND4C KHSRP	3.58e-05	503	86	8	16964243
Pubmed	Asymmetric distribution of PAR proteins in the mouse embryo begins at the 8-cell stage during compaction.	TJP1 MARK2	3.61e-05	4	86	2	15950600
Pubmed	Association of cell surface mucins with galectin-3 contributes to the ocular surface epithelial barrier.	MUC16 MUC1	3.61e-05	4	86	2	19556244
Pubmed	The necdin gene is deleted in Prader-Willi syndrome and is imprinted in human and mouse.	TJP1 NDN	3.61e-05	4	86	2	9302265
Pubmed	TRPV4 activation in human corneal epithelial cells promotes membrane mucin production.	MUC16 MUC1	3.61e-05	4	86	2	39024979
Pubmed	Clinical Performance of CEA, CA19-9, CA15-3, CA125 and AFP in Gastrointestinal Cancer Using LOCI™-based Assays.	MUC16 MUC1	3.61e-05	4	86	2	28011514
Pubmed	Suppression of Toll-like receptor-mediated innate immune responses at the ocular surface by the membrane-associated mucins MUC1 and MUC16.	MUC16 MUC1	3.61e-05	4	86	2	25563498
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	KIAA1671 TICRR KCNC1 PELP1 AFF3 PLEKHA1 ITM2C MARK2 ARMC6 VAT1	4.00e-05	832	86	10	36724073
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	KIDINS220 BASP1 TJP1 DIDO1 TANC1 DENND4C	4.31e-05	256	86	6	33397691
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	KIAA1671 AP4E1 HBS1L GAPVD1 TJP1 BRPF1 POLR1C TANC1 TNRC6C DNAH7	4.92e-05	853	86	10	28718761
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	AP4E1 CCP110 HBS1L GAPVD1 MROH6 TJP1 RPRD2 PROSER2 TNRC6C SNAPC3 DENND4C	5.03e-05	1038	86	11	26673895
Pubmed	Genetic mapping of the Mx influenza virus resistance gene within the region of mouse chromosome 16 that is homologous to human chromosome 21.	GAP43 ETS2	6.01e-05	5	86	2	2902234
Pubmed	The efficacy of serum carcinoembryonic antigen (CEA), cancer antigen 125 (CA125), carbohydrate antigen 19-9 (CA19-9), carbohydrate antigen 15-3 (CA15-3), alpha-fetoprotein (AFP) and human chorionic gonadotropin (hCG) levels in determining the malignancy of solitary pulmonary nodules.	MUC16 MUC1	6.01e-05	5	86	2	19383238
Pubmed	Reference intervals for carcinoembryonic antigen (CEA), CA125, MUC1, Alfa-foeto-protein (AFP), neuron-specific enolase (NSE) and CA19.9 from the NORIP study.	MUC16 MUC1	6.01e-05	5	86	2	18609108
Pubmed	Comparison of interspecific to intersubspecific backcrosses demonstrates species and sex differences in recombination frequency on mouse chromosome 16.	GAP43 ETS2	9.01e-05	6	86	2	1797230
Pubmed	Sex, strain, and species differences affect recombination across an evolutionarily conserved segment of mouse chromosome 16.	GAP43 ETS2	9.01e-05	6	86	2	1981993
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	KIAA1671 TOR1AIP2 ARHGAP23 BRPF1 ZBTB21 NFRKB ITM2C TANC1 TCF7L1 DCAF5 ARMC6	9.59e-05	1116	86	11	31753913
Pubmed	Identification of UHRF1/2 as new N-methylpurine DNA glycosylase-interacting proteins.	RPRD2 KHSRP MPG	1.16e-04	38	86	3	23537643
Pubmed	Deletion in the N-terminal half of olfactomedin 1 modifies its interaction with synaptic proteins and causes brain dystrophy and abnormal behavior in mice.	KIDINS220 TJP1 NFRKB	1.25e-04	39	86	3	24095980
Pubmed	The multipoint genetic mapping of mouse chromosome 16.	GAP43 ETS2	1.26e-04	7	86	2	1672298
Pubmed	The protein tyrosine phosphatase Pez is a major phosphatase of adherens junctions and dephosphorylates beta-catenin.	TJP1 CTNNA2	1.26e-04	7	86	2	12808048
Pubmed	Mouse chromosome-specific markers generated by PCR and their mapping through interspecific backcrosses.	GAP43 ETS2	1.26e-04	7	86	2	1774069
Pubmed	Genetic mapping of Prm-1, Igl-1, Smst, Mtv-6, Sod-1, and Ets-2 and localization of the Down syndrome region on mouse chromosome 16.	GAP43 ETS2	1.26e-04	7	86	2	2882955
Pubmed	The genetic origin of mouse annexin VIII.	ANXA8L1 ANXA8	1.26e-04	7	86	2	9434938
Pubmed	Adhesion protein VSIG1 is required for the proper differentiation of glandular gastric epithelia.	TJP1 CTNNA2	1.26e-04	7	86	2	21991385
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	GAPVD1 ZFAT ARHGAP23 BAZ2B	1.28e-04	103	86	4	10819331
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	KIAA1671 TOR1AIP2 CCP110 KIDINS220 AGL ITM2C DCAF5 VAT1	1.31e-04	606	86	8	36538041
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	ASNSD1 NGRN TJP1 PHF3 AGL COBLL1 DIDO1 CTNNA2 SPECC1L MARK2 TBC1D8B KHSRP	1.39e-04	1371	86	12	36244648
Pubmed	Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach.	FCHSD2 GAPVD1 LAMA5 PLEKHA1	1.43e-04	106	86	4	18654987
Pubmed	Schwann cell-derived Desert hedgehog controls the development of peripheral nerve sheaths.	GAP43 TJP1	1.68e-04	8	86	2	10482238
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	KIDINS220 CMTR1 PHF3 AKNAD1 SPECC1L	1.71e-04	208	86	5	33230847
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	CCP110 TICRR ARHGAP23 BASP1 TJP1 AFF3 PLEKHA1 DIDO1 SPECC1L JMY DENND4C	2.01e-04	1215	86	11	15146197
Pubmed	Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.	BASP1 MUC16 MUC1	2.05e-04	46	86	3	19190083
Pubmed	beta-Catenin protects the epidermis from mechanical stresses.	TJP1 CTNNA2	2.15e-04	9	86	2	23816618
Pubmed	Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures.	TJP1 MARK2	2.15e-04	9	86	2	11257119
Pubmed	IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5.	HBS1L GAPVD1 DCAF5 ARMC6 VAT1	2.27e-04	221	86	5	31950832
Pubmed	Protein microarray analysis identifies human cellular prion protein interactors.	ZFYVE28 BAZ2B MPG	2.33e-04	48	86	3	18482256
Pubmed	The emergent landscape of the mouse gut endoderm at single-cell resolution.	HOXB5 IRX1 TCF7L1	2.33e-04	48	86	3	30959515
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	TOR1AIP2 PELP1 BASP1 TJP1 PHF3 BRPF1 POLR1C LAMA5 SPECC1L	2.49e-04	847	86	9	35850772
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	GAPVD1 CMTR1 PELP1 AGL ZBTB21 CASZ1 HOXB13 KHSRP ARMC6	2.72e-04	857	86	9	25609649
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	CCP110 KIAA1549L PELP1 COBLL1 BRPF1	2.95e-04	234	86	5	36243803
Pubmed	Comprehensive interactome of Otx2 in the adult mouse neural retina.	BASP1 DIDO1 CASZ1	3.13e-04	53	86	3	26426291
Pubmed	Evolutionary diversification of the BetaM interactome acquired through co-option of the ATP1B4 gene in placental mammals.	TOR1AIP2 PHF3	3.28e-04	11	86	2	26939788
Pubmed	Tcf7L2 is essential for neurogenesis in the developing mouse neocortex.	TJP1 TCF7L1	3.28e-04	11	86	2	29751817
Pubmed	Scrib is required for epithelial cell identity and prevents epithelial to mesenchymal transition in the mouse.	TJP1 CTNNA2	3.28e-04	11	86	2	24095903
Pubmed	A large targeted deletion of Hoxb1-Hoxb9 produces a series of single-segment anterior homeotic transformations.	HOXB5 HOXB13	3.28e-04	11	86	2	10885747
Interaction	YWHAH interactions	KIAA1671 CCP110 TICRR GAPVD1 BASP1 TJP1 PHF3 COBLL1 ZBTB21 PLEKHA1 DCLRE1A TANC1 SPECC1L PROSER2 MARK2 DNAH7 DENND4C	2.89e-06	1102	85	17	int:YWHAH
Interaction	WWTR1 interactions	KIAA1671 HBS1L GAPVD1 TJP1 PHF3 DIDO1 RPRD2 NDN SPECC1L KHSRP	1.12e-05	422	85	10	int:WWTR1
Interaction	GOLGA1 interactions	KIAA1671 AP4E1 CCP110 GAPVD1 TANC1 JMY DENND4C	1.23e-05	183	85	7	int:GOLGA1
Interaction	EZR interactions	KIAA1671 KIDINS220 BASP1 TJP1 COBLL1 PLEKHA1 NDN TANC1 PROSER2 MARK2 JMY	2.05e-05	553	85	11	int:EZR
Interaction	VCL interactions	KIAA1671 CCP110 KIDINS220 TJP1 AGL BRME1 TANC1 TNRC6C	4.40e-05	305	85	8	int:VCL
Interaction	LYN interactions	PRUNE2 CCP110 HOXB5 HBS1L KIDINS220 BASP1 COBLL1 PLEKHA1 TANC1 MARK2 MUC1 DENND4C	4.76e-05	720	85	12	int:LYN
Interaction	YWHAG interactions	KIAA1671 CCP110 TICRR GAPVD1 ARHGAP23 TJP1 PHF3 COBLL1 ZBTB21 PLEKHA1 TANC1 SPECC1L PROSER2 MARK2 DNAH7 DENND4C	5.78e-05	1248	85	16	int:YWHAG
Interaction	YWHAB interactions	KIAA1671 CCP110 TICRR GAPVD1 ARHGAP23 BASP1 TJP1 PHF3 COBLL1 ZBTB21 PLEKHA1 TANC1 MARK2 DENND4C	8.20e-05	1014	85	14	int:YWHAB
Interaction	TERF2IP interactions	CMTR1 TJP1 PHF3 ANXA8L1 ZBTB21 NFRKB ETS2 DIDO1 MPG NPAT	1.09e-04	552	85	10	int:TERF2IP
Cytoband	Ensembl 112 genes in cytogenetic band chr9p22	BNC2 SNAPC3 DENND4C	1.39e-04	53	86	3	chr9p22
Cytoband	2q24.2	BAZ2B TANC1	7.82e-04	22	86	2	2q24.2
Cytoband	Xq22.3	NRK TBC1D8B	1.76e-03	33	86	2	Xq22.3
Cytoband	21q22.2	ETS2 IGSF5	1.76e-03	33	86	2	21q22.2
Cytoband	Ensembl 112 genes in cytogenetic band chr2q24	BAZ2B COBLL1 TANC1	1.79e-03	127	86	3	chr2q24
Cytoband	16p12.3	CCP110 VPS35L	1.87e-03	34	86	2	16p12.3
Cytoband	1p36.22	C1orf167 CASZ1	2.21e-03	37	86	2	1p36.22
Cytoband	10q11.22	ANXA8L1 ANXA8	2.71e-03	41	86	2	10q11.22
Cytoband	22q11.23	KIAA1671 SPECC1L	4.49e-03	53	86	2	22q11.23
Cytoband	15q26.1	NGRN TICRR	4.66e-03	54	86	2	15q26.1
GeneFamily	PHD finger proteins	BAZ2B PHF3 BRPF1 DIDO1	1.11e-04	90	50	4	88
GeneFamily	Annexins\|Endogenous ligands	ANXA8L1 ANXA8	5.73e-04	13	50	2	404
GeneFamily	CD molecules\|Mucins	MUC16 MUC1	1.52e-03	21	50	2	648
ToppCell	Control-Lymphoid-pDC\|Control / Condition, Lineage and Cell class	MYCL FCHSD2 ZFAT ARHGAP23 COBLL1 AFF3 ITM2C	5.15e-08	176	86	7	5de16ff65476bde8b23322a44e11412e14f1bafe
ToppCell	10x5'-Lung-Myeloid_Dendritic-pDC\|Lung / Manually curated celltypes from each tissue	FCHSD2 ZFAT ARHGAP23 COBLL1 AFF3 ITM2C	9.10e-07	168	86	6	90f713dae3fcbd6ca801a019e3861c263ff3366b
ToppCell	COVID_vent-Lymphocytic-Dendritic-pDC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.01e-06	171	86	6	779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCell	COVID_vent-Lymphocytic-Dendritic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.01e-06	171	86	6	debbb071d260639b16269c94d172766908325c58
ToppCell	BAL-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.12e-06	174	86	6	ab654e87c7eab7f33adc61be7a86da5c4d88008d
ToppCell	BAL-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.12e-06	174	86	6	d9bccff5258c4277bdd1edbd87e17c327ec125e8
ToppCell	BAL-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.12e-06	174	86	6	2453419842fd22d066631615403393bfe4449bb8
ToppCell	Control-Myeloid-pDC\|Control / Disease group,lineage and cell class （2021.01.30）	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.19e-06	176	86	6	baa3563973ea1a351fe028f55828463d2a51bf1a
ToppCell	metastatic_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.45e-06	182	86	6	02e04294fce12591c32d7bd0e866a000ad1f836e
ToppCell	PBMC-Severe-Myeloid-pDC-pDC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.65e-06	186	86	6	31df1eafa3010bc1be6fc4d4689f1393d69b6b13
ToppCell	PBMC-Severe-Myeloid-pDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.65e-06	186	86	6	eaa431ccd4cdd36fe06a44987603ec9979025aa8
ToppCell	Mild-Lymphoid-pDC\|Mild / Condition, Lineage, Cell class and cell subclass	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.65e-06	186	86	6	7fa82972c726025d6402e5eb7bf0db3b699eba4c
ToppCell	PBMC-Severe-Myeloid-pDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.65e-06	186	86	6	b95be984e308d4f9061274a35995ec558d434e74
ToppCell	PBMC-Severe-Myeloid-pDC-pDC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.65e-06	186	86	6	8f7949740286f64e034d1eb533ebc2c6f71ae966
ToppCell	PBMC-Severe-Myeloid-pDC-pDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.65e-06	186	86	6	95c7318e521fb6aa02e244b1e81e6b2a62107756
ToppCell	PBMC-Severe-Myeloid-pDC-pDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.65e-06	186	86	6	b70cd94c651b56dcf2e55554533a5f1130845390
ToppCell	COVID-19_Severe-Myeloid-pDC\|COVID-19_Severe / Disease group, lineage and cell class	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.65e-06	186	86	6	3db5ed69d49e5d79f990aca0295ddce4c297a05c
ToppCell	Mild-Lymphoid-pDC-\|Mild / Condition, Lineage, Cell class and cell subclass	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.65e-06	186	86	6	1d05e73ae2ec0cc27f79e4fa40d6b21790059f80
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 BNC2 NRK PLEKHA1 DNAH7 TCF7L1	1.70e-06	187	86	6	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	PBMC-Mild-Myeloid-pDC-pDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.75e-06	188	86	6	89411c4db3df5e1dc36cf8af4ffcc0abbecbe4df
ToppCell	PBMC-Mild-Myeloid-pDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.75e-06	188	86	6	de6a270b6e4fe09c39a52c296632d86ada98465b
ToppCell	PBMC-Mild-Myeloid-pDC-pDC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.75e-06	188	86	6	879054b780378ae05be68e597c77c931bf0ade03
ToppCell	PBMC-Mild-Myeloid-pDC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.81e-06	189	86	6	209cae68d78c8f72479b169e27c3ff7e143adece
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BNC2 HOXB5 GAP43 BASP1 CTNNA2 CNGB1	1.81e-06	189	86	6	3f5522be3e24dcdb6272f18cee2f239dfdeff9ad
ToppCell	PBMC-Mild-Myeloid-pDC-pDC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.81e-06	189	86	6	a9ad1fb12304541f909dd0eeac9b9eb28c31fd41
ToppCell	PBMC-Mild-Myeloid-pDC-pDC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.81e-06	189	86	6	98ca646231fbd5f29827c2dd31ac4503026bad7d
ToppCell	IPF-Epithelial-Basal\|IPF / Disease state, Lineage and Cell class	ARHGAP23 ANXA8L1 LAMA5 ANXA8 TANC1 TCF7L1	1.86e-06	190	86	6	ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KIAA1671 COBLL1 AFF3 SPARCL1 TANC1 CASZ1	1.86e-06	190	86	6	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	COVID-19_Severe-pDC\|COVID-19_Severe / disease group, cell group and cell class	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.86e-06	190	86	6	c5ab6b7492fb86aff3d2af3eb671c9f985ae4aeb
ToppCell	BAL-Severe-Myeloid-pDC-pDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.92e-06	191	86	6	989bf108c7f2c78dd7f14481570f1819673a5469
ToppCell	BAL-Severe-Myeloid-pDC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.92e-06	191	86	6	3e7fbe4af2c23b3b964becde843d2f088ad41c23
ToppCell	BAL-Severe-Myeloid-pDC-pDC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.92e-06	191	86	6	bc2f3c4e71e3a55fe76ea03f45746329a8fc81da
ToppCell	COVID-19-Lymphoid-pDC\|COVID-19 / Condition, Lineage and Cell class	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.92e-06	191	86	6	25343b11d42128ad16659e5519cd1673266cc505
ToppCell	BAL-Severe-Myeloid-pDC-pDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.98e-06	192	86	6	d9ff2293358c8b031ba212021012e058014ff472
ToppCell	Severe_COVID-19-Myeloid-pDC\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.98e-06	192	86	6	f79424c643a375dfe4579eff7ac1ba191e28a283
ToppCell	BAL-Severe-Myeloid-pDC-pDC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.98e-06	192	86	6	2e8611d65090e39f1a6e74c972288e7b68376d15
ToppCell	healthy_donor-Lymphocytic-B_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	FCHSD2 BASP1 COBLL1 AFF3 LAMA5 ITM2C	1.98e-06	192	86	6	7d9e5772b6e531b50ed4e4d6304ef11235f27f37
ToppCell	healthy_donor-Lymphocytic-B_cell-\|healthy_donor / Disease condition, Lineage, Cell class and subclass	FCHSD2 BASP1 COBLL1 AFF3 LAMA5 ITM2C	1.98e-06	192	86	6	975312f9d6cede4d4f5b737e481e5c73accc8c50
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAP43 TJP1 ETS2 SPARCL1 CASZ1 VAT1	1.98e-06	192	86	6	3c8603f977de34ee0d2bb50635f6722112a6a4db
ToppCell	BAL-Severe-Myeloid-pDC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.98e-06	192	86	6	43569726df281eebe57499e0993b9fd9d36118c2
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIAA1671 KIDINS220 BAZ2B AFF3 PLEKHA1 TCF7L1	2.04e-06	193	86	6	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIAA1671 KIDINS220 BAZ2B AFF3 PLEKHA1 TCF7L1	2.04e-06	193	86	6	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BNC2 HOXB5 GAP43 BASP1 CTNNA2 CNGB1	2.10e-06	194	86	6	5bd0f739aa75f387cca7c3b2686493ee2d1ee968
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.16e-06	195	86	6	fbc324c3435f32b9ca269d83333faecfe940d7fe
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-pDC-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.16e-06	195	86	6	06051de72b5c1e0d483a28b14dabd247dfca0ed9
ToppCell	COVID-19-Lymphoid-pDC\|Lymphoid / Condition, Lineage and Cell class	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.16e-06	195	86	6	4a7c080230ce6a79335ecbeadecb0177b2c13625
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-pDC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.16e-06	195	86	6	3aa44633c72658545aa2b35bf9d532c62f36a451
ToppCell	mild-pDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.29e-06	197	86	6	0cb00daa6943f7a7fb34a8fdf51188646af65686
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BNC2 HOXB5 GAP43 BASP1 CTNNA2 CNGB1	2.29e-06	197	86	6	5593721407f61fc5bc3f2f8bf8fa2604c4e29565
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BNC2 HOXB5 GAP43 BASP1 CTNNA2 CNGB1	2.29e-06	197	86	6	c220102fadbb7ba385a61704a144e0b814cb5c46
ToppCell	mild-pDC\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.29e-06	197	86	6	15230a54fa5903dd728de1a0ad633bd2d2c7a04d
ToppCell	severe-pDC\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.36e-06	198	86	6	22da4a29b9ff8b94d98bc69b4632a2a58d5dd9e6
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXB5 GAP43 BASP1 CTNNA2 CNGB1 VAT1	2.36e-06	198	86	6	328f1d5d8168e05edd301d3a0f2eb5c6cd1c67c8
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXB5 GAP43 BASP1 CTNNA2 CNGB1 VAT1	2.36e-06	198	86	6	7b9c7ce5d6b7df8db85943b65da1a2c202a8bb53
ToppCell	severe-pDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.36e-06	198	86	6	3c4820a8391088682fb3e47b914f872533bae227
ToppCell	COVID-19-COVID-19_Severe-Myeloid-pDC\|COVID-19_Severe / Disease, condition lineage and cell class	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.36e-06	198	86	6	033ed362333e1d33f2aeea8da5865d2228d154dc
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXB5 GAP43 BASP1 CTNNA2 CNGB1 VAT1	2.43e-06	199	86	6	646d6e84a2e70042ee5d68a045abb3fc6741fcc7
ToppCell	COVID-19-COVID-19_Mild-Myeloid-pDC\|COVID-19_Mild / Disease, condition lineage and cell class	MYCL FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.43e-06	199	86	6	9de61e5189d907cc969ac3043d68204f70acc0bf
ToppCell	proximal-3-mesenchymal-Pericyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HOXB5 FAM13C TJP1 ITM2C NDN SPARCL1	2.50e-06	200	86	6	98cbd0f4994e645f70c0bc5ebc1c3a3b28c6b67f
ToppCell	Control_saline-Endothelial-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	KIDINS220 TJP1 ETS2 PLEKHA1 TANC1 VAT1	2.50e-06	200	86	6	e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	KIDINS220 TJP1 AFF3 ETS2 TANC1 VAT1	2.50e-06	200	86	6	b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TJP1 COBLL1 AFF3 ETS2 TANC1 VAT1	2.50e-06	200	86	6	7034f57e282982c19c13ee8ab78eabaffa069e30
ToppCell	Control_saline-Endothelial-Endothelial-Alv_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	KIDINS220 TJP1 AFF3 ETS2 TANC1 VAT1	2.50e-06	200	86	6	abf4ba5fcb54cdeada0da1a8b956a30aa47679e4
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	TJP1 AFF3 ETS2 SPARCL1 TANC1 VAT1	2.50e-06	200	86	6	432384faeade8e609154fab3d96c955a8ec868dd
ToppCell	Control_saline-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	KIDINS220 TJP1 ETS2 PLEKHA1 TANC1 VAT1	2.50e-06	200	86	6	3372c488a39fe812fa94e4f0564594186fea3db5
ToppCell	proximal-mesenchymal-Pericyte\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HOXB5 FAM13C TJP1 ITM2C NDN SPARCL1	2.50e-06	200	86	6	03119a979bc912a98e6fc87addcbc25d8ecf2fb0
ToppCell	proximal-mesenchymal-Pericyte-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HOXB5 FAM13C TJP1 ITM2C NDN SPARCL1	2.50e-06	200	86	6	a81fde3d40b8efb3be535aeb2a44cfbdeb17bc8b
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-type_I_NK_T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TICRR KIDINS220 KCNC1 TANC1 MN1	9.47e-06	146	86	5	447c05414eda71681a0c07baba900f88ed6165ed
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT1_Precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	MYCL TEX38 IGSF5 LAMA5 MUC1	1.23e-05	154	86	5	8a643d91896af9b630a715fb284c1523d01ad1a3
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRK PROSER1 C1orf167 MN1 CNGB1	1.66e-05	164	86	5	d167c7a987b9b35d1e7725c803df4f9cd5380e47
ToppCell	10x5'-Liver-Myeloid_Dendritic-pDC\|Liver / Manually curated celltypes from each tissue	FCHSD2 ZFAT COBLL1 AFF3 ITM2C	1.76e-05	166	86	5	24dfa9f3e0842f9ab8350bf6a52ae0d10f2a0c44
ToppCell	lung-Ciliated_Epithelia\|lung / shred on tissue and cell subclass	HBS1L BASP1 MUC16 DNAH7 KHSRP	1.81e-05	167	86	5	26cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell	NS-moderate-d_07-13-Myeloid-pDC\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MYCL FCHSD2 ZFAT AFF3 ITM2C	1.87e-05	168	86	5	d03e91f0e0518b33555c0ec98124fc5ed0f11be5
ToppCell	10x5'-blood-Myeloid_Dendritic-pDC\|blood / Manually curated celltypes from each tissue	MYCL ZFAT COBLL1 AFF3 ITM2C	1.97e-05	170	86	5	59cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCell	COVID-pDC\|COVID / Condition, Cell_class and T cell subcluster	MYCL ZFAT COBLL1 AFF3 ITM2C	2.09e-05	172	86	5	3ecbb000495dde32f6153ef6bdea9c8802ff3985
ToppCell	facs-Marrow-KLS-18m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL BASP1 PLEKHA1 ITM2C PROSER2	2.09e-05	172	86	5	979fd7b435f59b8a4d290a809cf76147d4c63d48
ToppCell	facs-Marrow-KLS-18m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCL BASP1 PLEKHA1 ITM2C PROSER2	2.09e-05	172	86	5	f4d7f416802218ce56408fa4cb8a555d846bc85b
ToppCell	COVID-pDC-\|COVID / Condition, Cell_class and T cell subcluster	MYCL ZFAT COBLL1 AFF3 ITM2C	2.09e-05	172	86	5	a7827faa1afab51fdaf0cb1a2babcd2e00d411e5
ToppCell	COPD-Myeloid-pDC\|World / Disease state, Lineage and Cell class	FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.21e-05	174	86	5	be8227398300711ccda5ecc41ad34064bb246b19
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	ARHGAP23 COBLL1 PLEKHA1 MARK2 REV1	2.27e-05	175	86	5	0cc215109d9915af47e4d0a120ce2e46910715fa
ToppCell	BAL-Control-Myeloid-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.27e-05	175	86	5	6d5bdfbe53608e01c3845ecd908ca6d0fecc58f8
ToppCell	IPF-Myeloid-pDC\|World / Disease state, Lineage and Cell class	FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.27e-05	175	86	5	a06785a4ded01adfd29ca4c20f7759eccbe274cb
ToppCell	BAL-Control-Myeloid-pDC-pDC-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.27e-05	175	86	5	6839ee3bb4457d13cb08ca8eb79ae33ddd256783
ToppCell	BAL-Control-Myeloid-pDC-pDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.27e-05	175	86	5	9d6135e183179968555670abec39dff9da2c3219
ToppCell	Control-Myeloid-pDC\|Control / Disease state, Lineage and Cell class	FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.40e-05	177	86	5	3940663bb5b45b2ca9f772550380a516c53e410b
ToppCell	Control\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIAA1671 AFF3 PLEKHA1 TANC1 TCF7L1	2.40e-05	177	86	5	b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCell	Control-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.40e-05	177	86	5	e82115bfc32c7b689460fbc5caeb983c1aabe30f
ToppCell	COPD-Myeloid-pDC\|COPD / Disease state, Lineage and Cell class	FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.40e-05	177	86	5	415aa023195a7f961c09529f65cdcc7bb90eaf5d
ToppCell	IPF-Myeloid-pDC\|IPF / Disease state, Lineage and Cell class	FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.46e-05	178	86	5	8d9e28492e1f157bac3308aa947fd864ca16d277
ToppCell	Control-Myeloid-pDC\|World / Disease state, Lineage and Cell class	FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.46e-05	178	86	5	20ef63d925e67ddd5955832312ca8574a6f838a4
ToppCell	COPD-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.53e-05	179	86	5	29b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCell	IPF-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.60e-05	180	86	5	0f8567aa835d4e3a52f6631ae15216eca18a030c
ToppCell	moderate-Myeloid-pDC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FCHSD2 ZFAT COBLL1 AFF3 ITM2C	2.60e-05	180	86	5	1d8df7df03a71f49d6683554d3c948ce90dda42e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NRK COBLL1 PLEKHA1 PROSER2	2.67e-05	181	86	5	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BNC2 HOXB5 GAP43 CTNNA2 CNGB1	2.67e-05	181	86	5	7f99002a6411117cc2361334c7c9228e20c574b4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NRK COBLL1 PLEKHA1 PROSER2	2.74e-05	182	86	5	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	KIAA1671 FAM13C TJP1 COBLL1 VAT1	2.74e-05	182	86	5	fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXB5 GAP43 BASP1 CTNNA2 CNGB1	2.81e-05	183	86	5	7e2bac8b005155888ff4b41ef2e1d975dc17abc7
ToppCell	COPD-Stromal-Pericyte\|COPD / Disease state, Lineage and Cell class	FAM13C ITM2C NDN SPARCL1 TANC1	2.89e-05	184	86	5	a56264a22dfc2d3672b20134ab7c3c7c23da5ae1
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXB5 GAP43 BASP1 CTNNA2 CNGB1	2.89e-05	184	86	5	abb61e744a9031e0c91eb560a8f486a0ca5a01cc
Disease	dry eye syndrome (is_marker_for)	MUC16 MUC1	3.64e-04	10	85	2	DOID:10140 (is_marker_for)
Disease	diastolic blood pressure, systolic blood pressure	KIAA1671 BNC2 GAPVD1 PELP1 FAM13C DNAH7 TCF7L1 CASZ1	7.02e-04	670	85	8	EFO_0006335, EFO_0006336
Disease	cholangiocarcinoma (is_marker_for)	MUC16 ANXA8 MUC1	8.47e-04	64	85	3	DOID:4947 (is_marker_for)
Disease	photoreceptor cell layer thickness measurement	BASP1 MN1 DCAF5 CASZ1	8.98e-04	148	85	4	EFO_0803370
Disease	caudal middle frontal gyrus volume measurement	ZFAT KHSRP	1.22e-03	18	85	2	EFO_0010290
Disease	monocyte count	ZFYVE28 AP4E1 HBS1L ARHGAP23 BAZ2B DIDO1 ITM2C MN1 TCF7L1 CASZ1 NPAT	1.41e-03	1320	85	11	EFO_0005091
Disease	platelet component distribution width	PRUNE2 HBS1L GAPVD1 COBLL1 LAMA5 TCF7L1 JMY DCAF5	1.51e-03	755	85	8	EFO_0007984
Disease	Hodgkins lymphoma	HBS1L BRME1 TCF7L1	1.73e-03	82	85	3	EFO_0000183
Disease	forced expiratory volume	BNC2 ZFAT AGL AFF3 RPRD2 MUC1 MN1 CASZ1	1.98e-03	789	85	8	EFO_0004314
Disease	Prostatic Neoplasms	MYCL ACRBP BRPF1 IGSF5 RPRD2 CASZ1 HOXB13	2.02e-03	616	85	7	C0033578
Disease	Malignant neoplasm of prostate	MYCL ACRBP BRPF1 IGSF5 RPRD2 CASZ1 HOXB13	2.02e-03	616	85	7	C0376358
Disease	neutrophil count	PRUNE2 AP4E1 BNC2 HBS1L KIDINS220 ARHGAP23 RPRD2 ITM2C TCF7L1 CASZ1 VAT1	2.03e-03	1382	85	11	EFO_0004833
Disease	urate measurement, bone density	KIDINS220 BAZ2B ETS2 LAMA5 CTNNA2 TCF7L1 CASZ1	2.08e-03	619	85	7	EFO_0003923, EFO_0004531
Disease	pulse pressure measurement	BNC2 ZFAT KIAA1549L GAP43 COBLL1 LAMA5 DCLRE1A CTNNA2 TCF7L1 CASZ1 DENND4C	2.14e-03	1392	85	11	EFO_0005763

Protein segments in the cluster

Peptide	Gene	Start	Entry
PHFSSPEAEPASSNK	AFF3	451	P51826
SDASHKENVSPKPAA	C1orf167	191	Q5SNV9
SSKTSPDISHQPAAA	nan	116	Q9N2J8
ASDSGESAHKAEAPA	BNC2	996	Q6ZN30
NTEAAFPASAAETKP	CASZ1	1066	Q86V15
AALSNPKATSSSPAH	BAZ2B	456	Q9UIF8
DSEPKFHSESLSSNP	ACRBP	251	Q8NEB7
APKVSADGSQEPTHD	ARMC6	76	Q6NXE6
HAPEASQPAENISKD	AKIP1	156	Q9NQ31
KSFDSASQVPNPAAA	SPECC1L	846	Q69YQ0
TSAAAKSVHAAPNPA	COBLL1	881	Q53SF7
FHPPQSTAASVAKES	AP4E1	886	Q9UPM8
SDVLETASKSANPPH	HBS1L	206	Q9Y450
APAATHAAPQATREK	ZFYVE28	701	Q9HCC9
GDSHPESQNTDDKPS	NPAT	711	Q14207
KSSSHFNPDPDAETL	ANXA8	16	P13928
ESHSPALADSETPKA	MUC16	5136	Q8WXI7
SKDPPELHAAASSES	KIDINS220	1746	Q9ULH0
EAGQDHPPSKASSVE	KIAA1671	211	Q9BY89
IPKSASAPSAHLFDS	JMY	851	Q8N9B5
HVTSNPVHAADSPAK	NFRKB	1011	Q6P4R8
PVHAADSPAKASSAS	NFRKB	1016	Q6P4R8
PGHEASSKDPNHSTA	NGRN	176	Q9NPE2
SADDLPDSASQAAHP	GAPVD1	1096	Q14C86
PDSASQAAHPQDSAF	GAPVD1	1101	Q14C86
TTPPAHDVTSAPDNK	MUC1	111	P15941
KAAEAAAAPAESAAP	BASP1	121	P80723
LTNNSGTPKDHDSPE	ETS2	266	P15036
HPTAANSSDAKATPF	FAM214B	271	Q7L5A3
TSHKDNPAPSSSKEA	DCAF5	696	Q96JK2
DSANPLHLSAAPENS	KIAA1549L	146	Q6ZVL6
SDPKPAVAAAAHVSA	MROH6	651	A6NGR9
SNKAHPASNAIDGTE	LAMA5	111	O15230
APPSHRKGDSNANSD	PELP1	506	Q8IZL8
DKADKASASAPAPAS	ITM2C	16	Q9NQX7
ASPVKAINHPSASAA	PROSER1	286	Q86XN7
DSHGAKPSASSPSDQ	HOXB5	106	P09067
TSSKQTHVAPAAPEA	NR0B1	151	P51843
IPSKHALDSADSQPA	CEFIP	451	Q711Q0
ASHPQASFNLASPEK	IGSF5	386	Q9NSI5
AQPNDPSASEHTHFK	KCNC1	371	P48547
PSSHANGDPVAVAKA	BRME1	571	Q0VDD7
KSSSHFNPDPDAETL	ANXA8L1	16	Q5VT79
NAAQATSPTDEAKGH	CTNNA2	256	P26232
SPEPFSVKNEQSHAE	DNAH7	71	Q8WXX0
KHDSSAPDPAPDSAD	DIDO1	886	Q9BTC0
DASAIVAKHSQPSPE	DENND4C	956	Q5VZ89
DAAQAPAEQPHSSSD	MPG	36	P29372
EKAPHSDSTPNSDTG	AKNAD1	636	Q5T1N1
HVENEAFPKTSSATP	CCP110	181	O43303
ADLTNSSAPSPSHKV	MARK2	381	Q7KZI7
SKDVAAAAADSPNKH	ASNSD1	386	Q9NWL6
AAAADSPNKHVSVPD	ASNSD1	391	Q9NWL6
TKAKPDEPEFHSAQS	DCLRE1A	426	Q6PJP8
SPSANEKSLHAESPG	FCHSD2	681	O94868
KAAFADSSGQHPPDA	HOXB13	196	Q92826
SNPFTKEAALAHAAP	RPRD2	1241	Q5VT52
SDDEPPSSVSHGAKA	CMTR1	31	Q8N1G2
AHDLPANKASASQPG	MN1	1261	Q10571
APSAPDHESDNKDIS	NRK	1121	Q7Z2Y5
DPSKAAAAAADPNAA	KHSRP	561	Q92945
DPSHSPSDKVGRADA	TOR1AIP2	116	Q8NFQ8
SAASPLEQNPSKHGA	TNRC6C	1311	Q9HCJ0
AAASAAPSHSQKPSV	SUPT20HL1	496	Q3ZLR7
SANVKDTHSPDAPAA	PRUNE2	1256	Q8WUY3
TPAAEDAAAKATAQP	GAP43	181	P17677
PSAHEALKSAPSSFA	PROSER2	346	Q86WR7
EDKAEAPHAPAAPSA	IRX1	246	P78414
HEAKADNEPSCSPAA	TANC1	121	Q9C0D5
CTRNPHAAKDSSDPN	POLR1C	146	O15160
ADGTDSADPSPVHKD	FAM13C	191	Q8NE31
FSNTPDQAPEHISKD	SNAPC3	231	Q92966
TPHPAACDKDGQTDS	BRPF1	846	P55201
AEAASSGVPATKQHP	CNGB1	451	Q14028
VKNPSPASSSHAVLD	ZBTB21	601	Q9ULJ3
NDTSSAEAHAAPEKP	ZFAT	601	Q9P243
HDSLADTASAASPVP	TICRR	461	Q7Z2Z1
PDHFSPENANDTAKE	VPS35L	261	Q7Z3J2
ESEAAQSCHPKPVSS	MYCL	261	P12524
AHLPTSPDTNKAESS	REV1	896	Q9UBZ9
PANEKEAESAKHSPE	TBC1D8B	941	Q0IIM8
LASPAAPAATHSEQA	TCF7L1	486	Q9HCS4
PEPAGARAHSDNKDS	ARHGAP23	1431	Q9P227
DHSKPTAETVAPDNT	SPARCL1	26	Q14515
LNVHPAASASKPSAD	PHF3	911	Q92576
AASHLSEPAKPAHSQ	TJP1	1376	Q07157
PKTEAASDPQHPAAS	VAT1	21	Q99536
PSESKHAFRPTNAAT	PLEKHA1	306	Q9HB21
APAAHQKPEASVEQA	XIRP1	1511	Q702N8
RSHADQDSNPKAEAP	TEX38	111	Q6PEX7
SPHFKSGSLAVDNAD	AGL	871	P35573
PNFAAEAPNSEVHSS	NDN	11	Q99608