Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainETS_DOMAIN_1

ETS1 ETV1 ELF5 ELK4

1.21e-0628544PS00345
DomainETS_DOMAIN_2

ETS1 ETV1 ELF5 ELK4

1.21e-0628544PS00346
DomainETS

ETS1 ETV1 ELF5 ELK4

1.21e-0628544SM00413
DomainEts_dom

ETS1 ETV1 ELF5 ELK4

1.21e-0628544IPR000418
DomainETS_DOMAIN_3

ETS1 ETV1 ELF5 ELK4

1.21e-0628544PS50061
DomainEts

ETS1 ETV1 ELF5 ELK4

1.21e-0628544PF00178
Domain5HT1F_rcpt

HTR1E HTR1F

8.21e-062542IPR000450
Domain-

ARID2 ETS1 ETV1 ELF5 ELK4 RFX4

3.82e-052185461.10.10.10
DomainWHTH_DNA-bd_dom

ARID2 ETS1 ETV1 ELF5 ELK4 RFX4

6.83e-05242546IPR011991
DomainRFX_DNA_binding

ARID2 RFX4

2.92e-049542PF02257
DomainDNA-bd_RFX

ARID2 RFX4

2.92e-049542IPR003150
DomainRFX_DBD

ARID2 RFX4

2.92e-049542PS51526
Domain5HT_rcpt

HTR1E HTR1F

2.92e-049542IPR002231
DomainPNT

ETS1 ELF5

4.44e-0411542PS51433
DomainPointed_dom

ETS1 ELF5

4.44e-0411542IPR003118
DomainSAM_PNT

ETS1 ELF5

4.44e-0411542PF02198
DomainSAM_PNT

ETS1 ELF5

4.44e-0411542SM00251
DomainTPR-like_helical_dom

CLTCL1 USP28 EIF3L TTC13 CDC27

5.56e-04233545IPR011990
DomainPSI

ATRN PLXNB1

3.85e-0332542PF01437
DomainPlexin_repeat

ATRN PLXNB1

3.85e-0332542IPR002165
DomainPSI

ATRN PLXNB1

7.18e-0344542IPR016201
DomainPSI

ATRN PLXNB1

7.83e-0346542SM00423
Pubmed

ETS-dependent regulation of a distal Gata4 cardiac enhancer.

ETS1 ETV1 ELF5 ELK4

5.39e-082454422056786
Pubmed

ETS-family genes in pancreatic development.

ETS1 ETV1 ELF5 ELK4

1.20e-072954417907201
Pubmed

Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg.

ETS1 ETV1 ELF5 ELK4

1.20e-072954426097038
Pubmed

Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships.

HTR1E HTR1F

2.37e-06254221422162
Pubmed

The inhibition of Kir2.1 potassium channels depolarizes spinal microglial cells, reduces their proliferation, and attenuates neuropathic pain.

KCNJ2 CX3CR1

2.37e-06254232220118
Pubmed

Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype.

HTR1E HTR1F

2.37e-0625421608964
Pubmed

The regulation of COUP-TFII gene expression by Ets-1 is enhanced by the steroid receptor co-activators.

ETS1 ETV1

7.09e-06354215541767
Pubmed

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer.

ETS1 ETV1

7.09e-06354217671502
Pubmed

Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner.

IFNB1 CX3CR1

1.42e-05454228959042
Pubmed

The ETS-domain transcription factor family.

ELF5 ELK4

1.42e-0545429570133
Pubmed

Structural insights into the ligand binding and Gi coupling of serotonin receptor 5-HT5A.

HTR1E HTR1F

2.36e-05554235610220
Pubmed

Loss of Trex1 in Dendritic Cells Is Sufficient To Trigger Systemic Autoimmunity.

IFNB1 CX3CR1

3.54e-05654227511730
Pubmed

c-Fos oncogene regulator Elk-1 interacts with BRCA1 splice variants BRCA1a/1b and enhances BRCA1a/1b-mediated growth suppression in breast cancer cells.

ETS1 ELK4

3.54e-05654211313879
Pubmed

Suicide and serotonin: study of variation at seven serotonin receptor genes in suicide completers.

HTR1E HTR1F

4.94e-05754212627464
Pubmed

Cytosolic sequestration of spatacsin by Protein Kinase A and 14-3-3 proteins.

SPG11 YWHAE

4.94e-05754236096339
Pubmed

A Population of Radio-Resistant Macrophages in the Deep Myenteric Plexus Contributes to Postoperative Ileus Via Toll-Like Receptor 3 Signaling.

IFNB1 CX3CR1

4.94e-05754233519804
Pubmed

Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains.

ETS1 ETV1

6.59e-0585429681824
Pubmed

Brainwide Genetic Sparse Cell Labeling to Illuminate the Morphology of Neurons and Glia with Cre-Dependent MORF Mice.

ETV1 CX3CR1

6.59e-05854232795398
Pubmed

Temporal requirement of dystroglycan glycosylation during brain development and rescue of severe cortical dysplasia via gene delivery in the fetal stage.

FKTN ETV1

8.46e-05954229360985
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ATRN GLT8D1 FKTN LPCAT3 PGAP1 TTC13 HACD2 YWHAE PLXNB1

8.89e-05120154935696571
Pubmed

The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint.

USP28 CDC27

1.55e-041254218662541
Pubmed

Pigmentation-related genes and their implication in malignant melanoma susceptibility.

ATRN HPS1

2.13e-041454219320733
Pubmed

Function of PEA3 Ets transcription factors in mammary gland development and oncogenesis.

ETS1 ETV1

2.13e-041454214635793
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

LPCAT3 DOCK9 ZNF335 PGAP1 ETS1

2.50e-0436354514691545
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

NSA2 DOCK9 PGAP1 HPS1 ETS1 BOD1L1 CDC27 PLXNB1

2.53e-04108454811544199
Pubmed

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.

ANXA3 ETS1

3.56e-041854222446963
Pubmed

Association study of the serotoninergic system in migraine in the Spanish population.

HTR1E HTR1F

3.56e-041854219455600
Pubmed

Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor.

ETS1 ETV1

3.56e-041854225117710
Pubmed

SLFN11 Inactivation Induces Proteotoxic Stress and Sensitizes Cancer Cells to Ubiquitin Activating Enzyme Inhibitor TAK-243.

EIF3L SF3A3 YWHAE

4.43e-049554333863777
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

EIF3L OTUB1 SF3A3 ELF5 CDC27 NOP2

5.14e-0465354633742100
Pubmed

TIM-1 Ubiquitination Mediates Dengue Virus Entry.

ABCG2 YWHAE

5.86e-042354229742433
Pubmed

Phosphodiesterase 2A2 regulates mitochondria clearance through Parkin-dependent mitophagy.

GLT8D1 CISD1 LPCAT3

6.10e-0410654333087821
Pubmed

Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver.

ETS1 ELK4

6.39e-042454234215813
Pubmed

HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25.

CCNB3 YWHAE

7.51e-042654211531413
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

ETS1 ETV1 ELF5 ELK4

7.51e-0426354420932939
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

OTUB1 ETS1 ETV1 ELF5 ELK4 RNF145

7.90e-0470954622988430
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

ATRN GLT8D1 EIF3L OTUB1 BOD1L1 TTC13 CDC27 YWHAE

8.29e-04129754833545068
Pubmed

Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.

USP28 BOD1L1 CDC27

8.53e-0411954323508102
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

CISD1 LPCAT3 EIF3L OTUB1 SF3A3 HACD2 CDC27 YWHAE

9.33e-04132154827173435
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

TMEM230 EIF3L SF3A3 BOD1L1 SPG11 TTC13

9.39e-0473354634672954
Pubmed

Autophagy negatively regulates cancer cell proliferation via selectively targeting VPRBP.

CLTCL1 PGAP1

1.00e-033054222963397
Pubmed

Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer.

ETS1 ETV1

1.00e-033054221575865
Pubmed

Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection.

NSA2 YWHAE

1.14e-033254214613977
Pubmed

Paradoxical mitotic exit induced by a small molecule inhibitor of APC/CCdc20.

ANXA3 CDC27

1.21e-033354232152539
Pubmed

The DNA sequence and comparative analysis of human chromosome 20.

TMEM230 ATRN CRLS1 ZNF335 PTPRT

1.24e-0351754511780052
Pubmed

A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate.

USP28 OTUB1

1.44e-033654222626734
Pubmed

Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.

OTUB1 NOP2 YWHAE

1.48e-0314454335681168
GeneFamilyETS transcription factor family

ETS1 ETV1 ELF5 ELK4

3.65e-0728394534
GeneFamily5-hydroxytryptamine receptors, G protein-coupled

HTR1E HTR1F

3.48e-0413392170
ToppCelldroplet-Bladder-nan-3m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRN CISD1 EBPL PGAP1 ELF5 HACD2

1.33e-07195546d6e2a5a15bea16de5f7ff09318c67d46ea923203
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRN EBPL PGAP1 ELF5 HACD2

2.91e-06184545382b1e90b3f437af596750669c0465a169d97095
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRN EBPL PGAP1 TMEM63B HACD2

3.15e-06187545aa336fb568a24e12c0454265ddd71ed10a6614cf
ToppCellCOVID-CD4-CD4_Treg|COVID / Condition, Cell_class and T cell subcluster

SPG11 SCAI ME3 CYB561

4.14e-05159544037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PGAP1 ETV1 NOP2 ME3

4.45e-0516254464353d33af0e82ebb7cf2bba74d52ca0586a58fc
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

HTR1F ANXA3 ABCG2 PLXNB1

4.78e-051655447b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ANXA3 TMEM63B PLXNB1 SCAI

6.56e-051795441603117b52623663458a977c94bf7f9f6c1114b8
ToppCellCOVID-19-kidney-NK|COVID-19 / Disease (COVID-19 only), tissue and cell type

USP28 ETS1 P2RY8 CX3CR1

6.85e-051815448906ee8a7a1616dfe8c3b5c73988416641213629
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK9 ETS1 ABCG2 CYB561

7.77e-05187544f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

ANXA3 TMEM63B ETV1 ELF5

7.77e-0518754411670a85db87cbb3e78022a589632173604b0940
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

ANXA3 TMEM63B ETV1 ELF5

7.77e-051875440277d4e54bd4d48f30241c2951a569209423fee8
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

TMEM63B ETV1 ELF5 RNF145

8.26e-0519054427a1a86620fe9b5ee930d388b32352206485e6d0
ToppCelldroplet-Lung-nan-21m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA3 DOCK9 ABCG2 ME3

8.43e-0519154492b2faa72c184b6ae49530fd3b50848510904997
ToppCellhematopoetic_progenitors-CD34+_CLP|World / Lineage and Cell class

EBPL ABCG2 YWHAE SCAI

8.43e-0519154432f2537c97c9984629d61c6f34a337f555146ad4
ToppCelldroplet-Lung-nan-21m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA3 DOCK9 ABCG2 ME3

8.43e-05191544d0bbbf42d00165a53253c833adef65da6ec36bba
ToppCellASK452-Immune-NK_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

FKTN ETS1 P2RY8 CX3CR1

8.60e-05192544f04ee5aaa54c39b7493098fb3d2f78168d6b8060
ToppCelldroplet-Bladder-nan-3m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRN CISD1 EBPL PGAP1

8.78e-05193544268925bfe85fb94a93a4ff8fe078d692df888140
ToppCellmild_COVID-19_(asymptomatic)-CD4+_Tcm|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

PGAP1 ETS1 P2RY8 CYB561

8.78e-05193544498d3a83bce6deff69aea71b18a43688e0a8ed7d
ToppCelldroplet-Bladder-nan-3m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRN CISD1 EBPL HACD2

8.78e-05193544ee91a796d0f6d4cee7a93a525689e716fdceeda5
ToppCelldroplet-Lung-21m-Endothelial-venous_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANXA3 DOCK9 ABCG2 ME3

8.95e-05194544db7b0c77ad88f7b74d85679f1fb8ee7140ac3f62
ToppCelldroplet-Lung-21m-Endothelial-venous_endothelial-vein_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANXA3 DOCK9 ABCG2 ME3

8.95e-0519454417d530982789acc5e6889b215f3d433d138a41c4
ToppCelldroplet-Bladder-nan-3m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EBPL ANXA3 ETS1 TMEM63B

8.95e-0519454437803f4abf1aa1ad771c9cd293933003d7101e70
ToppCelldroplet-Lung-21m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANXA3 DOCK9 ABCG2 ME3

8.95e-051945445992b9409d5855eff2afc3acd201ccd25420d2e0
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid|BALF-PFMC / Compartment, severity and other cell annotations on 10x 3' data (130k)

NSA2 KCNJ2 EIF3L ETS1

9.32e-051965446361c37b0292ba9e5bf485a4809d2b0cd894c26e
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

USP28 ETS1 P2RY8 CX3CR1

9.50e-051975442b3a56bb1d40bc1284a5931c4e7b373660de5402
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD8+_Tem|COVID-19_Severe / Disease group, lineage and cell class

USP28 ETS1 P2RY8 CX3CR1

9.50e-05197544f0bac4d5c3160933ac3786cec8dadffb35d711ea
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ETS1 P2RY8 SPG11 CX3CR1

9.50e-05197544836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

USP28 ETS1 P2RY8 CX3CR1

9.50e-05197544f73ece3aca28c0db5db0f12e026d42c6c36b9efb
ToppCellAT2_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

KCNJ2 TMEM63B ETV1 RNF145

9.50e-051975445e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCellT_cells-CTLs|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

USP28 P2RY8 SPG11 CX3CR1

9.50e-0519754428117cf300e169182571fbad0de1681a484a435a
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USP28 ETS1 P2RY8 CX3CR1

9.50e-05197544e70e7d97823a762def3970d94a0e897981a6c922
ToppCellAT2_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

KCNJ2 ETV1 ELF5 RNF145

9.50e-05197544fd7bdfa6bf5966ebc11fdd13915769429540ddbf
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

USP28 ETS1 P2RY8 CX3CR1

9.50e-05197544bce0135a96910d2bace62a3408a1a6fdac0cf0df
ToppCellControl_saline-Epithelial_alveolar-AT_2-AT2|Control_saline / Treatment groups by lineage, cell group, cell type

HTR1E EBPL ETV1 ELF5

9.50e-05197544f870a26f322668781e3d2832c5d9ef2c7c91011f
ToppCellT_cells-CTLs|World / Immune cells in Kidney/Urine in Lupus Nephritis

USP28 ETS1 P2RY8 CX3CR1

9.50e-051975442de34e20915a247bee75aa40495e23c20bb23e18
ToppCellVE-CD8-CD8_1|VE / Condition, Cell_class and T cell subcluster

USP28 ETS1 P2RY8 CX3CR1

9.69e-051985449747a486fddec917a3753651de0b2079ac2385ee
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

DOCK9 PGAP1 ETS1 CYB561

9.69e-05198544ee71543559836fd59adc0da877b2ca538cba60cb
ToppCellmedial-Hematologic-Natural_Killer|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

USP28 ETS1 P2RY8 CX3CR1

9.88e-051995444a75ef6a3b7b5d779a08d039a79322cd60b4ef65
ToppCelldistal-Hematologic-Natural_Killer-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

USP28 ETS1 P2RY8 CX3CR1

9.88e-05199544928b152f3bade90dfdb15e46aaa0c85063db0026
ToppCellmedial-2-Hematologic-Natural_Killer|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

USP28 ETS1 P2RY8 CX3CR1

9.88e-0519954452338b8970fba0b32578748ba0bec0b344171ca6
ToppCellmedial-Hematologic-Natural_Killer-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

USP28 ETS1 P2RY8 CX3CR1

9.88e-05199544dfcc4976688c7e6df5e41ae77436710075f1f779
ToppCelldistal-Hematologic-Natural_Killer_T-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ETS1 P2RY8 RFX4 CX3CR1

9.88e-05199544cf9c5b2a7d2b53d06d2f8edd1b2d12b6719ebfef
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HTR1F ANXA3 DOCK9 ABCG2

9.88e-0519954463c01e8961f48ed1bed4ab619cacf318cd6de7b9
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD8+_Tem|COVID-19_Severe / Disease, condition lineage and cell class

USP28 ETS1 P2RY8 CX3CR1

1.01e-0420054431859b8db7ea17e48b7b54e92f0d76aeb755e7ca
ToppCellBiopsy_IPF-Epithelial-SCGB3A2+|Biopsy_IPF / Sample group, Lineage and Cell type

ANXA3 TMEM63B ELF5 RNF145

1.01e-042005442aaf130d702d18c277d16b6800f006a53ed653fb
ToppCelldistal-Hematologic-Natural_Killer|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

USP28 ETS1 P2RY8 CX3CR1

1.01e-0420054433947befb9d32ec00f9f3e7eedaac478dcd63b20
ToppCellmild-CD8+_T_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NSA2 DOCK9 ETS1 ELK4

1.01e-04200544c825320599a61a4c629d736f5c0fd6f1f405540a
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYO3A CLTCL1 ANXA3

3.49e-04113543b795a0c65114b3c0758fe3720e8a80247f900971
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Nxph2_Wls|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HTR1F ETV1 ME3

5.25e-0413054305d5a73acf1d7f75a79876b1a06d27c74a89b8a4
ToppCellCOVID_non-vent-Myeloid-Monocytic-Developing_Neutrophil|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

MYO3A CLTCL1 ANXA3

5.37e-041315435b29f0dc449b9fff5e8bf6365080168f31b7e268
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO3A ELF5 PTPRT

6.12e-04137543b831d917f5073ccff158662adb281d34f023126a
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO3A ELF5 PTPRT

6.12e-04137543cf3e928d9a7a7349840bb87475a42a07f65b94f0
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO3A ELF5 PTPRT

6.12e-041375435d82d6c7eef4ec7a7fae60e37fb956488314987e
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYO3A CLTCL1 ANXA3

6.93e-041435439836a040a2ebcf6f05431e658a7b8fd566621452
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MYO3A CLTCL1 ANXA3

6.93e-041435434622c221b5d2d4cd4f37e4f81662e073924e1507
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ATRN KCNJ2 ABCG2

7.35e-04146543447c05414eda71681a0c07baba900f88ed6165ed
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma|TCGA-Uterus / Sample_Type by Project: Shred V9

LPCAT3 ELF5 TTC13

8.11e-041515432810bfa01bd3016aeba29735eb4a9284792e8aac
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-Treg|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ETS1 CX3CR1 SCAI

9.07e-041575432c767c526abcc8adea6ec4eb2cc333060bb213b5
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

USP28 ETS1 CX3CR1

9.41e-04159543bf8ff9251bcb64b2b9d6dd93461aec97659686ec
ToppCell390C-Epithelial_cells-Epithelial-A_(AT2)|390C / Donor, Lineage, Cell class and subclass (all cells)

NUDT6 TMEM63B ETV1

9.58e-04160543731def6d82814ebac1a400bc7aea5f6da43ec960
ToppCell390C-Epithelial_cells-Epithelial-A_(AT2)-|390C / Donor, Lineage, Cell class and subclass (all cells)

NUDT6 TMEM63B ETV1

9.58e-04160543cf27b4ac4d0caa6f9b068dc8ea93472470a01a4d
ToppCellCOVID-19_Moderate-MAIT|World / disease group, cell group and cell class

ETS1 SUN3 CYB561

9.58e-04160543bf73c5fe87c1f243edec17d7a2c30fae5e2cfd6b
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HTR1F RNF145 PLXNB1

9.58e-04160543af84da18c85037f49f55e8958f00f12140226982
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HTR1F RNF145 PLXNB1

9.58e-04160543f7ca98beaa24f9674d503588eb15d341c4135d77
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CLTCL1 ANXA3 ETV1

9.58e-04160543bb1bb3673059768c0ea0160d29fff127f3a4ecb4
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HTR1F RNF145 PLXNB1

9.58e-04160543a76ad44b5f25f59d6b9333fb45f8bb96196a3090
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLTCL1 ANXA3 ETV1

9.58e-0416054376f49b8b4450fa8acd36326bfa36a5d1f4bd95fb
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-1|TCGA-Kidney / Sample_Type by Project: Shred V9

ETS1 P2RY8 ABCG2

9.76e-041615436cacae4a759ace763597ee394cff498dc5d96f74
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HTR1F ABCG2 ME3

9.93e-0416254358da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HTR1F ABCG2 ME3

9.93e-041625434d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCellfacs-Lung-Endomucin-24m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUDT6 NSA2 PLXNB1

9.93e-04162543497ae9f86a5e7946d0fde932b35719a382a6b691
ToppCellfacs-Lung-Endomucin-24m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUDT6 NSA2 PLXNB1

9.93e-041625437b2949eba2b4aea239d96ed82aafab13b07624eb
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Tem/emra_CD8|GI_small-bowel / Manually curated celltypes from each tissue

CCNB3 ANXA3 CX3CR1

1.01e-031635431a8c79903ed416f286ebe8a9922233affbc55d82
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ETV1 NOP2 ME3

1.01e-031635439f5facfa1864eb63e2f8022ad7379d9252b7a254
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Brinp3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HTR1F ABCG2 ME3

1.01e-03163543b0aa4a620bd58011225b42ea6dda04e3101ba342
ToppCellCOVID-19_Severe-CD4+_T_activated|COVID-19_Severe / Disease condition and Cell class

HTR1F SERPINB13 ETS1

1.07e-031665430f138dbafad6f83975944e8f6398411127b150cc
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BOD1L1 NOP2 SCAI

1.08e-03167543a54b8e03987a7b067173121902e1811a3d003692
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

CCNB3 PGAP1 CDC27

1.08e-03167543c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANXA3 ETV1 PLXNB1

1.08e-03167543c7d1e84af1f4d7430858287520ac2cfa36203642
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANXA3 ETV1 PLXNB1

1.08e-031675434e613be2b3ba01160b0c0254fce3c4f72220e580
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANXA3 ETV1 PLXNB1

1.08e-0316754318ad85751bd892309627eefc357eb28ec5a7c300
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYO3A PGAP1 PTPRT

1.12e-031695438bca402e144819cb9a8d431d6bf9429be2fff6d6
ToppCellCOVID-19_Mild-PLT_2|World / Disease Group and Platelet Clusters

USP28 SF3A3 NOP2

1.12e-031695436abfdc8b437f19c03b408bedc245059d28c6ba6a
ToppCellInfluenza_Severe-Neutrophil|World / Disease group and Cell class

VNN2 KCNJ2 ANXA3

1.12e-031695436e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

ATRN SERPINB13 LPCAT3

1.16e-03171543adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCellT_cells-GNLY+GZMB+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SERPINB13 USP28 CX3CR1

1.16e-0317154304c811817cfec45af5f2891793106cc7ddb0300e
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HTR1F ETV1 PTPRT

1.16e-03171543f648789e6aefe508bb748401bf9b3cd830fb0ddf
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

VNN2 ANXA3 BOD1L1

1.16e-031715432b7c5a557c4bc5c573211c4d618bdd6766a24916
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-mature_NK_T_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EBPL ETS1 CX3CR1

1.16e-03171543a0462781d22c391b3c6c8a72586c385ac089ca5d
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l4|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EBPL ETS1 CX3CR1

1.16e-0317154385b655dc8a3cbf0e8097e951116490e326a795ac
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

VNN2 ANXA3 BOD1L1

1.16e-03171543dcb15bc54aeea06ef8f07f1134f3ff1e21ac0e4f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANXA3 DOCK9 ABCG2

1.18e-03172543c3a99828838af3b85c8c885d69cc8018f55ced50
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VIL1 ABCG2 ME3

1.18e-03172543fc092a0631555d79e00ef9890cbd806e15bca2d4
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VIL1 ABCG2 ME3

1.18e-03172543745725bd10c82017d678463b8fef0d2dcf09a8fd
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

CCNB3 PGAP1 CDC27

1.20e-0317354342c911ed16fabdabef063830e8407192d8bde950
ToppCellCOVID-19_Mild-PLT_2|COVID-19_Mild / Disease Group and Platelet Clusters

SF3A3 INTS3 NOP2

1.20e-03173543d11705e56b6b21eec963ea224717f27680c781ed
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

KCNJ2 ANXA3 DOCK9

1.20e-03173543ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HTR1F ETV1 PTPRT

1.20e-03173543ee972d9cc68755926512fd3bbe1267098c67cd94
ToppCellBAL-Severe-Myeloid-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

VNN2 KCNJ2 ANXA3

1.20e-031735435b76d9cc56bbb29017e64a2d0a3c76c0be003d96
ToppCellBAL-Severe-Myeloid-Neutrophil-Neutrophil-Neu_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

VNN2 KCNJ2 ANXA3

1.20e-03173543bf685025961e79b379f2c35464b6c8ce3e31ace0
Drugalniditan

IFNB1 HTR1E HTR1F

2.05e-0611543CID000066004
Diseasesensory peripheral neuropathy, remission

ETV1 PTPRT

8.11e-0423542EFO_0009785, MONDO_0002321
DiseaseSecondary Biliary Cholangitis

NSA2 ABCG2

2.70e-0342542C0238065
DiseaseBiliary cirrhosis

NSA2 ABCG2

2.70e-0342542C0023892
DiseaseBiliary Cirrhosis, Primary, 1

NSA2 ABCG2

2.70e-0342542C4551595
Diseasecoffee consumption measurement, tea consumption measurement

ABCG2 HACD2

2.96e-0344542EFO_0006781, EFO_0010091
DiseasePrimary biliary cirrhosis

NSA2 ABCG2

3.37e-0347542C0008312

Protein segments in the cluster

PeptideGeneStartEntry
YYKMKGDYHRYLAEF

YWHAE

121

P62258
YYKIYRAAKTLYHKR

HTR1F

201

P30939
EKKLFIHEYISGYYR

ABCG2

451

Q9UNQ0
LYYRIYHAAKSLYQK

HTR1E

201

P28566
QYYLRYLEKYEKVHH

ARID2

91

Q68CP9
DIRTEFKKHYGYSLY

ANXA3

286

P12429
AGEKFRRYLYHLYGK

CX3CR1

296

P49238
FDYHRKKGYADLYSL

CYB561

106

P49447
YEKLSRALRYYYKTG

ELF5

226

Q9UKW6
YDSLKAVYYKYSHPV

CCNB3

1351

Q8WWL7
YIELHRKRYGYRLDY

NSA2

6

O95478
KYHYYGIAVKESSQY

RFX4

126

Q33E94
KIGYHLLYYLRASKA

INTS3

686

Q68E01
IVSRLFYGKSYYHVY

P2RY8

261

Q86VZ1
FYGKSYYHVYKLTLC

P2RY8

266

Q86VZ1
YYKVDYSRFHKTYEV

KCNJ2

336

P63252
LYKELYYRHIYAKVS

EIF3L

131

Q9Y262
VRYGHSLALYKDKIY

ATRN

391

O75882
YEKLSRGLRYYYDKN

ETS1

386

P14921
VALHELYKYINKYYD

PLXNB1

2086

O43157
AVYTGLFYKLYHKEL

NUDT6

291

P53370
YDKLSRSLRYYYEKG

ETV1

386

P50549
LFYRHYLFYKETYLI

LPCAT3

56

Q6P1A2
LIYAIVKEKYYRHFL

EBPL

116

Q9BY08
YNYIGYLDYKKERIR

GLT8D1

216

Q68CQ7
RRNAYSYSYYLKLAK

PTPRT

771

O14522
KVYLLYRPGHYDILY

OTUB1

256

Q96FW1
VRHAYVHKPYLYSKY

BOD1L1

466

Q8NFC6
VHKPYLYSKYYSDSD

BOD1L1

471

Q8NFC6
NHLYVYPKYLKYDSQ

DOCK9

641

Q9BZ29
YDKLSRALRYYYVKN

ELK4

56

P28324
VRAYLAKGSYHSLYY

HACD2

61

Q6Y1H2
YMLLKHLVDRYNLYY

TMEM63B

651

Q5T3F8
YYGRILHYLKAKEYS

IFNB1

146

P01574
LLFQLYYYKHYLSTK

FKTN

21

O75072
YYYKHYLSTKNGAGL

FKTN

26

O75072
KVLDYAYKHNLASYY

ME3

551

Q16798
LGGDYYRKLLRYYSK

HPS1

641

Q92902
TCYYRSGKAYKAYRL

CDC27

46

P30260
YSYYHYGRKTVQVIK

CRLS1

286

Q9UJA2
KLAKRYPAYELYLYG

PGAP1

56

Q75T13
YLNRLKKDLAIYYSY

NOP2

266

P46087
GVIYLITKYGYLHLY

CLTCL1

271

P53675
IGYLAYKRFYVKDHR

CISD1

26

Q9NZ45
YYKLAYEHKFYEIVN

SPG11

2411

Q96JI7
GKLVARYHKYHLYSE

VNN2

171

O95498
YTYLIGEKQHYLLYV

VIL1

431

P09327
YLKVKYLREYSRYLH

TTC13

426

Q8NBP0
FLQKYLDYVEKYYHA

SERPINB13

116

Q9UIV8
LYAIIAEYGSRLYKY

SUN3

81

Q8TAQ9
IASKIGQLYYHYYLR

SCAI

126

Q8N9R8
KGKYQEALSYLVYAY

USP28

911

Q96RU2
YGRYLDLHDCYLKYI

SF3A3

136

Q12874
YKYLALNMHYVGYIL

RNF145

51

Q96MT1
PSRRFLGKKYRKYYY

ZNF335

441

Q9H4Z2
HLRIAYYASKGYRGY

TMEM230

96

Q96A57
FHIFYYIYAGLAEKK

MYO3A

526

Q8NEV4