Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	RALGDS ITSN2 SH2D3C OBSCN ARFGEF2 EPS8L3 ARHGEF10L	5.81e-05	231	85	7	GO:0005085
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RALGDS ITSN2 SH2D3C OBSCN ARFGEF2 EPS8L3 SGSM3 ARHGEF10L ARAP1	3.04e-04	507	85	9	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RALGDS ITSN2 SH2D3C OBSCN ARFGEF2 EPS8L3 SGSM3 ARHGEF10L ARAP1	3.04e-04	507	85	9	GO:0030695
GeneOntologyMolecularFunction	type 1 angiotensin receptor binding	TYK2 ARAP1	3.71e-04	7	85	2	GO:0031702
GeneOntologyMolecularFunction	vasopressin receptor activity	AVPR1B NLRP6	3.71e-04	7	85	2	GO:0005000
GeneOntologyMolecularFunction	ATP-dependent peptidase activity	SPG7 LONP2	4.93e-04	8	85	2	GO:0004176
GeneOntologyMolecularFunction	angiotensin receptor binding	TYK2 ARAP1	7.88e-04	10	85	2	GO:0031701
Domain	Ion_trans_dom	KCNG2 KCNA4 TRPC4 TRPC5 SCN5A KCNH4	1.17e-05	114	83	6	IPR005821
Domain	Ion_trans	KCNG2 KCNA4 TRPC4 TRPC5 SCN5A KCNH4	1.17e-05	114	83	6	PF00520
Domain	TRP_dom	TRPC4 TRPC5	2.89e-04	6	83	2	IPR013555
Domain	TRP_2	TRPC4 TRPC5	2.89e-04	6	83	2	PF08344
Domain	WD40_repeat_dom	WDR38 GTF3C2 TULP4 TEP1 LYST RFWD3 ARHGEF10L	3.54e-04	297	83	7	IPR017986
Domain	TRPC_channel	TRPC4 TRPC5	4.04e-04	7	83	2	IPR002153
Domain	PH_dom-like	TYK2 ITSN2 OBSCN EPS8L3 NIBAN3 LYST ARHGEF10L ARAP1	6.07e-04	426	83	8	IPR011993
Domain	-	WDR38 GTF3C2 TULP4 TEP1 LYST RFWD3 ARHGEF10L	7.00e-04	333	83	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	WDR38 GTF3C2 TULP4 TEP1 LYST RFWD3 ARHGEF10L	7.25e-04	335	83	7	IPR015943
Domain	ARM-type_fold	FOCAD PELP1 MTOR MROH2A ARFGEF2 PPP6R2 LYST	7.77e-04	339	83	7	IPR016024
Domain	Ubiquitin_CS	UBB UBC	8.58e-04	10	83	2	IPR019954
Domain	WD40	WDR38 GTF3C2 TULP4 TEP1 LYST RFWD3	1.04e-03	259	83	6	PF00400
Domain	TRP_channel	TRPC4 TRPC5	1.05e-03	11	83	2	IPR004729
Domain	Ubiquitin	UBB UBC	1.05e-03	11	83	2	IPR019956
Domain	WD40	WDR38 GTF3C2 TULP4 TEP1 LYST RFWD3	1.24e-03	268	83	6	SM00320
Domain	WD40_repeat	WDR38 GTF3C2 TULP4 TEP1 LYST RFWD3	1.33e-03	272	83	6	IPR001680
Domain	WD_REPEATS_1	WDR38 GTF3C2 TULP4 TEP1 LYST RFWD3	1.49e-03	278	83	6	PS00678
Domain	WD_REPEATS_2	WDR38 GTF3C2 TULP4 TEP1 LYST RFWD3	1.52e-03	279	83	6	PS50082
Domain	WD_REPEATS_REGION	WDR38 GTF3C2 TULP4 TEP1 LYST RFWD3	1.52e-03	279	83	6	PS50294
Domain	AAA	SPG7 LONP2 PEX1	1.60e-03	52	83	3	PF00004
Domain	ATPase_AAA_core	SPG7 LONP2 PEX1	1.78e-03	54	83	3	IPR003959
Domain	Channel_four-helix_dom	KCNG2 KCNA4 SCN5A	2.08e-03	57	83	3	IPR027359
Domain	-	KCNG2 KCNA4 SCN5A	2.08e-03	57	83	3	1.20.120.350
Domain	MAM_1	MAMDC4 NPNT	2.25e-03	16	83	2	PS00740
Domain	MAM	MAMDC4 NPNT	2.54e-03	17	83	2	SM00137
Domain	MAM	MAMDC4 NPNT	2.85e-03	18	83	2	PF00629
Domain	MAM_dom	MAMDC4 NPNT	2.85e-03	18	83	2	IPR000998
Domain	MAM_2	MAMDC4 NPNT	2.85e-03	18	83	2	PS50060
Domain	RhoGEF	ITSN2 OBSCN ARHGEF10L	3.44e-03	68	83	3	SM00325
Domain	RhoGEF	ITSN2 OBSCN ARHGEF10L	3.74e-03	70	83	3	PF00621
Domain	DH_2	ITSN2 OBSCN ARHGEF10L	3.74e-03	70	83	3	PS50010
Domain	DH-domain	ITSN2 OBSCN ARHGEF10L	3.89e-03	71	83	3	IPR000219
Domain	-	ITSN2 OBSCN ARHGEF10L	3.89e-03	71	83	3	1.20.900.10
Domain	NACHT	TEP1 NLRP6	4.65e-03	23	83	2	PS50837
Domain	NACHT_NTPase	TEP1 NLRP6	4.65e-03	23	83	2	IPR007111
Domain	RASGEF	RALGDS SH2D3C	5.92e-03	26	83	2	PS00720
Domain	WD40_repeat_CS	WDR38 GTF3C2 TEP1 LYST	6.15e-03	164	83	4	IPR019775
Domain	K_chnl_volt-dep_Kv	KCNG2 KCNA4	6.37e-03	27	83	2	IPR003968
Domain	ARM-like	PELP1 MTOR MROH2A ARFGEF2 PPP6R2	7.07e-03	270	83	5	IPR011989
Domain	ZnF_U1	ZFR2 ZNF622	7.33e-03	29	83	2	SM00451
Domain	Znf_U1	ZFR2 ZNF622	7.33e-03	29	83	2	IPR003604
Domain	RASGEF_CAT	RALGDS SH2D3C	7.33e-03	29	83	2	PS50009
Domain	RasGEF	RALGDS SH2D3C	7.83e-03	30	83	2	PF00617
Domain	-	RALGDS SH2D3C	7.83e-03	30	83	2	1.10.840.10
Domain	Ras_GEF_dom	RALGDS SH2D3C	7.83e-03	30	83	2	IPR023578
Domain	RASGEF_cat_dom	RALGDS SH2D3C	7.83e-03	30	83	2	IPR001895
Domain	RasGEF	RALGDS SH2D3C	7.83e-03	30	83	2	SM00147
Pathway	REACTOME_PTK6_REGULATES_RTKS_AND_THEIR_EFFECTORS_AKT1_AND_DOK1	UBB UBC ARAP1	6.68e-06	9	62	3	M27732
Pathway	REACTOME_PTK6_REGULATES_RTKS_AND_THEIR_EFFECTORS_AKT1_AND_DOK1	UBB UBC ARAP1	6.68e-06	9	62	3	MM15482
Pathway	REACTOME_INACTIVATION_OF_CSF3_G_CSF_SIGNALING	TYK2 UBB UBC	6.31e-05	18	62	3	MM15680
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	UBB UBC TRPC4 TRPC5 ASPH	7.27e-05	99	62	5	MM14910
Pathway	REACTOME_SIGNALING_BY_PTK6	UBB UBC PELP1 ARAP1	9.10e-05	54	62	4	M29742
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	UBB UBC TRPC4 TRPC5 ASPH	1.01e-04	106	62	5	M27200
Pathway	REACTOME_ER_QUALITY_CONTROL_COMPARTMENT_ERQC	UBB UBC	1.14e-04	4	62	2	MM15591
Pathway	REACTOME_SIGNALING_BY_CSF3_G_CSF	TYK2 UBB UBC	1.18e-04	22	62	3	MM15675
Pathway	REACTOME_PEROXISOMAL_PROTEIN_IMPORT	UBB UBC LONP2 PEX1	1.66e-04	63	62	4	M27915
Pathway	REACTOME_INACTIVATION_OF_CSF3_G_CSF_SIGNALING	TYK2 UBB UBC	1.74e-04	25	62	3	M41829
Pathway	REACTOME_PEROXISOMAL_PROTEIN_IMPORT	UBB UBC LONP2 PEX1	1.88e-04	65	62	4	MM15628
Pathway	KEGG_MEDICUS_REFERENCE_UCHL1_MEDIATED_HYDROLYSIS	UBB UBC	1.89e-04	5	62	2	M49036
Pathway	REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE	UBB UBC OBSCN ARHGEF10L	2.50e-04	70	62	4	MM14824
Pathway	REACTOME_SIGNALING_BY_CSF3_G_CSF	TYK2 UBB UBC	3.02e-04	30	62	3	M41825
Pathway	REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE	UBB UBC OBSCN ARHGEF10L	3.43e-04	76	62	4	M19832
Pathway	REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS	UBB UBC	3.94e-04	7	62	2	MM15593
Pathway	REACTOME_CALNEXIN_CALRETICULIN_CYCLE	UBB UBC	3.94e-04	7	62	2	MM15592
Pathway	REACTOME_MODULATION_BY_MTB_OF_HOST_IMMUNE_SYSTEM	UBB UBC	3.94e-04	7	62	2	M29822
Pathway	REACTOME_FLT3_SIGNALING_BY_CBL_MUTANTS	UBB UBC	3.94e-04	7	62	2	M41737
Pathway	REACTOME_INTERFERON_ALPHA_BETA_SIGNALING	TYK2 UBB UBC	4.40e-04	34	62	3	MM15631
Pathway	REACTOME_EVASION_BY_RSV_OF_HOST_INTERFERON_RESPONSES	TYK2 UBB UBC	4.80e-04	35	62	3	M48246
Pathway	REACTOME_REGULATION_OF_TP53_DEGRADATION	UBB UBC MTOR	5.22e-04	36	62	3	MM15339
Pathway	BIOCARTA_STAT3_PATHWAY	TYK2 MTOR	5.24e-04	8	62	2	MM1576
Pathway	BIOCARTA_STAT3_PATHWAY	TYK2 MTOR	5.24e-04	8	62	2	M22063
Pathway	WP_INSULIN_SIGNALING_IN_ADIPOCYTES_DIABETIC_CONDITION	MTOR SLC2A4	5.24e-04	8	62	2	M39537
Pathway	WP_INSULIN_SIGNALING_IN_ADIPOCYTES_NORMAL_CONDITION	MTOR SLC2A4	5.24e-04	8	62	2	M39447
Pathway	REACTOME_MAPK1_ERK2_ACTIVATION	TYK2 IL6R	5.24e-04	8	62	2	MM14507
Pathway	REACTOME_CYCLIN_A_CDK2_ASSOCIATED_EVENTS_AT_S_PHASE_ENTRY	UBB UBC RBL2 CDC25B	5.26e-04	85	62	4	M27674
Pathway	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING	UBB UBC OBSCN ARHGEF10L	5.26e-04	85	62	4	MM14746
Pathway	REACTOME_REGULATION_OF_TP53_EXPRESSION_AND_DEGRADATION	UBB UBC MTOR	5.66e-04	37	62	3	M27641
Pathway	REACTOME_INLA_MEDIATED_ENTRY_OF_LISTERIA_MONOCYTOGENES_INTO_HOST_CELLS	UBB UBC	6.72e-04	9	62	2	M27781
Pathway	REACTOME_MAPK3_ERK1_ACTIVATION	TYK2 IL6R	6.72e-04	9	62	2	MM14474
Pathway	REACTOME_INTERLEUKIN_6_SIGNALING	TYK2 IL6R	6.72e-04	9	62	2	MM14470
Pathway	REACTOME_DOWNREGULATION_OF_ERBB4_SIGNALING	UBB UBC	6.72e-04	9	62	2	M26930
Pathway	REACTOME_MAPK1_ERK2_ACTIVATION	TYK2 IL6R	6.72e-04	9	62	2	M26918
Pathway	REACTOME_REGULATION_OF_PTEN_LOCALIZATION	UBB UBC	6.72e-04	9	62	2	M27814
Pathway	REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1	UBB UBC	6.72e-04	9	62	2	MM14676
Pathway	REACTOME_PREVENTION_OF_PHAGOSOMAL_LYSOSOMAL_FUSION	UBB UBC	6.72e-04	9	62	2	M29819
Pathway	REACTOME_MYOCLONIC_EPILEPSY_OF_LAFORA	UBB UBC	6.72e-04	9	62	2	M27276
Pathway	REACTOME_DOWNREGULATION_OF_ERBB4_SIGNALING	UBB UBC	6.72e-04	9	62	2	MM14535
Pathway	REACTOME_S_PHASE	UBB UBC RBL2 MCM5 CDC25B	7.39e-04	163	62	5	M3158
Pathway	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	KCNG2 KCNA4 KCNH4	7.67e-04	41	62	3	MM14546
Pathway	REACTOME_MAPK3_ERK1_ACTIVATION	TYK2 IL6R	8.37e-04	10	62	2	M26896
Pathway	REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN_1_SIGNALING	TRPC4 TRPC5	8.37e-04	10	62	2	M27330
Pathway	REACTOME_REGULATION_OF_PTEN_LOCALIZATION	UBB UBC	8.37e-04	10	62	2	MM15539
Pathway	REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS	UBB UBC	8.37e-04	10	62	2	MM14849
Pathway	REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX	UBB UBC	8.37e-04	10	62	2	MM15647
Pathway	REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX	UBB UBC	8.37e-04	10	62	2	M27925
Pathway	REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING	UBB UBC OBSCN ARHGEF10L	8.66e-04	97	62	4	M9400
Pathway	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	KCNG2 KCNA4 KCNH4	8.82e-04	43	62	3	M1056
Pathway	REACTOME_CYCLIN_D_ASSOCIATED_EVENTS_IN_G1	UBB UBC RBL2	9.44e-04	44	62	3	MM15377
Pathway	REACTOME_REGULATION_OF_TBK1_IKK_MEDIATED_ACTIVATION_OF_IRF3_IRF7_UPON_TLR3_LIGATION	UBB UBC	1.02e-03	11	62	2	M48241
Pathway	REACTOME_REGULATION_OF_BACH1_ACTIVITY	UBB UBC	1.02e-03	11	62	2	M41833
Pathway	REACTOME_INTERLEUKIN_6_SIGNALING	TYK2 IL6R	1.02e-03	11	62	2	M1014
Pathway	REACTOME_ALPHA_PROTEIN_KINASE_1_SIGNALING_PATHWAY	UBB UBC	1.02e-03	11	62	2	M29827
Pathway	REACTOME_PEXOPHAGY	UBB UBC	1.02e-03	11	62	2	M29846
Pathway	REACTOME_TICAM1_TRAF6_DEPENDENT_INDUCTION_OF_TAK1_COMPLEX	UBB UBC	1.02e-03	11	62	2	M27885
Pathway	REACTOME_ALPHA_PROTEIN_KINASE_1_SIGNALING_PATHWAY	UBB UBC	1.02e-03	11	62	2	MM15668
Pathway	REACTOME_PEXOPHAGY	UBB UBC	1.02e-03	11	62	2	MM15673
Pathway	REACTOME_REGULATION_OF_BACH1_ACTIVITY	UBB UBC	1.02e-03	11	62	2	MM15686
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	UBB UBC TRPC4 TRPC5 ASPH	1.04e-03	176	62	5	MM15718
Pathway	PID_RHOA_REG_PATHWAY	OBSCN ARHGEF10L ARAP1	1.07e-03	46	62	3	M68
Pathway	REACTOME_PROTEIN_LOCALIZATION	UBB UBC LONP2 PEX1	1.08e-03	103	62	4	MM15653
Pathway	REACTOME_CYCLIN_D_ASSOCIATED_EVENTS_IN_G1	UBB UBC RBL2	1.14e-03	47	62	3	M29724
Pathway	REACTOME_SIGNALING_BY_PTK6	UBB UBC ARAP1	1.22e-03	48	62	3	MM15479
Pathway	REACTOME_JOSEPHIN_DOMAIN_DUBS	UBB UBC	1.22e-03	12	62	2	M27577
Pathway	WP_SREBF_AND_MIR33_IN_CHOLESTEROL_AND_LIPID_HOMEOSTASIS	MTOR SREBF1	1.22e-03	12	62	2	MM15927
Pathway	REACTOME_JOSEPHIN_DOMAIN_DUBS	UBB UBC	1.22e-03	12	62	2	MM15288
Pathway	REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING	UBB UBC	1.22e-03	12	62	2	MM14550
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	UBB UBC TRPC4 TRPC5 ASPH	1.24e-03	183	62	5	M997
Pathway	REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES	UBB UBC	1.44e-03	13	62	2	MM14827
Pathway	REACTOME_NF_KB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL	UBB UBC	1.44e-03	13	62	2	MM14828
Pathway	REACTOME_MAP3K8_TPL2_DEPENDENT_MAPK1_3_ACTIVATION	UBB UBC	1.44e-03	13	62	2	MM15280
Pathway	REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING	UBB UBC	1.44e-03	13	62	2	M549
Pathway	REACTOME_SUPPRESSION_OF_PHAGOSOMAL_MATURATION	UBB UBC	1.44e-03	13	62	2	M29823
Pathway	REACTOME_REGULATION_OF_INNATE_IMMUNE_RESPONSES_TO_CYTOSOLIC_DNA	UBB UBC	1.44e-03	13	62	2	MM14931
Pathway	REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES	UBB UBC	1.44e-03	13	62	2	M14582
Pathway	REACTOME_TICAM1_DEPENDENT_ACTIVATION_OF_IRF3_IRF7	UBB UBC	1.44e-03	13	62	2	M27884
Pathway	REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING	UBB UBC	1.44e-03	13	62	2	M967
Pathway	REACTOME_NF_KB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL	UBB UBC	1.44e-03	13	62	2	M736
Pathway	REACTOME_REGULATION_OF_TBK1_IKK_IKBKE_MEDIATED_ACTIVATION_OF_IRF3_IRF7	UBB UBC	1.67e-03	14	62	2	M48239
Pathway	REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS	UBB UBC	1.67e-03	14	62	2	MM14826
Pathway	REACTOME_GLYCOGEN_SYNTHESIS	UBB UBC	1.67e-03	14	62	2	M27247
Pathway	REACTOME_NEGATIVE_REGULATION_OF_FLT3	UBB UBC	1.67e-03	14	62	2	MM15682
Pathway	REACTOME_IRAK1_RECRUITS_IKK_COMPLEX	UBB UBC	1.67e-03	14	62	2	M935
Pathway	KEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_SEQUESTOSOME_1_LIKE_RECEPTOR	UBB UBC	1.67e-03	14	62	2	M47975
Pathway	REACTOME_NEGATIVE_REGULATORS_OF_DDX58_IFIH1_SIGNALING	UBB UBC	1.67e-03	14	62	2	MM15642
Pathway	REACTOME_INLB_MEDIATED_ENTRY_OF_LISTERIA_MONOCYTOGENES_INTO_HOST_CELL	UBB UBC	1.93e-03	15	62	2	M27774
Pathway	REACTOME_REGULATION_OF_TBK1_IKK_IKBKE_MEDIATED_ACTIVATION_OF_IRF3_IRF7	UBB UBC	1.93e-03	15	62	2	MM17228
Pathway	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION	UBB UBC	1.93e-03	15	62	2	MM14875
Pathway	REACTOME_REGULATION_OF_INNATE_IMMUNE_RESPONSES_TO_CYTOSOLIC_DNA	UBB UBC	1.93e-03	15	62	2	M27229
Pathway	REACTOME_NEGATIVE_REGULATION_OF_FLT3	UBB UBC	1.93e-03	15	62	2	M41735
Pathway	REACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER	UBB UBC	1.93e-03	15	62	2	M27202
Pathway	REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE	UBB UBC	1.93e-03	15	62	2	MM15175
Pathway	BIOCARTA_RACC_PATHWAY	TRPC4 TRPC5	1.93e-03	15	62	2	M22002
Pathway	REACTOME_IRAK1_RECRUITS_IKK_COMPLEX	UBB UBC	1.93e-03	15	62	2	MM15645
Pathway	WP_ID_SIGNALING	RBL2 SREBF1	2.20e-03	16	62	2	M39359
Pathway	REACTOME_VLDLR_INTERNALISATION_AND_DEGRADATION	UBB UBC	2.20e-03	16	62	2	M27761
Pathway	REACTOME_MAP3K8_TPL2_DEPENDENT_MAPK1_3_ACTIVATION	UBB UBC	2.20e-03	16	62	2	M27567
Pathway	REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS	UBB UBC	2.20e-03	16	62	2	M7257
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TYK2 FOCAD PALD1 SPG7 TULP4 MTOR ESYT1 SCN5A SREBF1 OBSCN ARFGEF2 MCM5 FHIP1B TEP1 CHPF LYST ARHGEF10L ARAP1	2.82e-10	1105	88	18	35748872
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	TYK2 RALGDS LONP2 RECQL4 ASPH SREBF1 PEX1 UQCRC2 CDC25B PPP6R2 RFWD3	7.77e-07	650	88	11	38777146
Pubmed	Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C.	UBB UBC	6.33e-06	2	88	2	29130934
Pubmed	Cloning of human polyubiquitin cDNAs and a ubiquitin-binding assay involving its in vitro translation product.	UBB UBC	6.33e-06	2	88	2	9644242
Pubmed	The ubiquitin-proteasome system as a prospective molecular target for cancer treatment and prevention.	UBB UBC	6.33e-06	2	88	2	20491623
Pubmed	Hybrid troponin reconstituted from vertebrate and arthropod subunits.	UBB UBC	6.33e-06	2	88	2	124018
Pubmed	Simultaneous Disruption of Both Polyubiquitin Genes Affects Proteasome Function and Decreases Cellular Proliferation.	UBB UBC	6.33e-06	2	88	2	32705536
Pubmed	Inhibition of mTOR signaling reduces PELP1-mediated tumor growth and therapy resistance.	PELP1 MTOR	6.33e-06	2	88	2	24688046
Pubmed	Structure of a new crystal form of tetraubiquitin.	UBB UBC	6.33e-06	2	88	2	11173499
Pubmed	Ubiquitination of human immunodeficiency virus type 1 Gag is highly dependent on Gag membrane association.	UBB UBC	6.33e-06	2	88	2	17609272
Pubmed	Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.	TRPC4 TRPC5	6.33e-06	2	88	2	22457348
Pubmed	Conserved gating elements in TRPC4 and TRPC5 channels.	TRPC4 TRPC5	6.33e-06	2	88	2	23677990
Pubmed	Involvement of TRPC4 and 5 Channels in Persistent Firing in Hippocampal CA1 Pyramidal Cells.	TRPC4 TRPC5	6.33e-06	2	88	2	32033274
Pubmed	Heterogeneous structure of the polyubiquitin gene UbC of HeLa S3 cells.	UBB UBC	6.33e-06	2	88	2	8917096
Pubmed	The first ankyrin-like repeat is the minimum indispensable key structure for functional assembly of homo- and heteromeric TRPC4/TRPC5 channels.	TRPC4 TRPC5	6.33e-06	2	88	2	17624425
Pubmed	Assembly of mTORC3 Involves Binding of ETV7 to Two Separate Sequences in the mTOR Kinase Domain.	MTOR ETV7	6.33e-06	2	88	2	39337528
Pubmed	The emerging complexity of protein ubiquitination.	UBB UBC	6.33e-06	2	88	2	19754430
Pubmed	Cloning and sequence analysis of a cDNA encoding poly-ubiquitin in human ovarian granulosa cells.	UBB UBC	6.33e-06	2	88	2	2820408
Pubmed	Downregulation of TRPC4 and TRPC5 Inhibits Smooth Muscle Cell Proliferation without Affecting Endothelial Cell Proliferation.	TRPC4 TRPC5	6.33e-06	2	88	2	34899056
Pubmed	Corticolimbic expression of TRPC4 and TRPC5 channels in the rodent brain.	TRPC4 TRPC5	6.33e-06	2	88	2	17593972
Pubmed	Structure of ubiquitin refined at 1.8 A resolution.	UBB UBC	6.33e-06	2	88	2	3041007
Pubmed	Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice.	TRPC4 TRPC5	6.33e-06	2	88	2	26317356
Pubmed	The human ubiquitin multigene family: some genes contain multiple directly repeated ubiquitin coding sequences.	UBB UBC	6.33e-06	2	88	2	2988935
Pubmed	A novel capacitative calcium entry channel expressed in excitable cells.	TRPC4 TRPC5	6.33e-06	2	88	2	9687496
Pubmed	Regulation of SREBP1c expression by mTOR signaling in hepatocytes.	MTOR SREBF1	6.33e-06	2	88	2	20847591
Pubmed	Insulin-induced de novo lipid synthesis occurs mainly via mTOR-dependent regulation of proteostasis of SREBP-1c.	MTOR SREBF1	6.33e-06	2	88	2	31541353
Pubmed	Higher frequency of concerted evolutionary events in rodents than in man at the polyubiquitin gene VNTR locus.	UBB UBC	6.33e-06	2	88	2	9504932
Pubmed	Synthetic, structural and biological studies of the ubiquitin system: the total chemical synthesis of ubiquitin.	UBB UBC	6.33e-06	2	88	2	8166633
Pubmed	Lineage-specific homogenization of the polyubiquitin gene among human and great apes.	UBB UBC	6.33e-06	2	88	2	14745543
Pubmed	TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A.	TRPC4 TRPC5	6.33e-06	2	88	2	30038709
Pubmed	Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity.	UBB UBC	1.90e-05	3	88	2	20826778
Pubmed	Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory.	TRPC4 TRPC5	1.90e-05	3	88	2	28790178
Pubmed	Modulation of HIV-1 Rev protein abundance and activity by polyubiquitination with unconventional Lys-33 branching.	UBB UBC	1.90e-05	3	88	2	17067581
Pubmed	Differential PI(4,5)P2 sensitivities of TRPC4, C5 homomeric and TRPC1/4, C1/5 heteromeric channels.	TRPC4 TRPC5	1.90e-05	3	88	2	30755645
Pubmed	Characterization of two polyubiquitin binding sites in the 26 S protease subunit 5a.	UBB UBC	1.90e-05	3	88	2	9488668
Pubmed	A ubiquitin-interacting motif from Hrs binds to and occludes the ubiquitin surface necessary for polyubiquitination in monoubiquitinated proteins.	UBB UBC	1.90e-05	3	88	2	12207904
Pubmed	Polymorphisms in stearoyl coa desaturase and sterol regulatory element binding protein interact with N-3 polyunsaturated fatty acid intake to modify associations with anthropometric variables and metabolic phenotypes in Yup'ik people.	SREBF1 SLC2A4	1.90e-05	3	88	2	27467133
Pubmed	Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition.	UBB UBC	1.90e-05	3	88	2	15826667
Pubmed	Disruption of polyubiquitin gene Ubc leads to attenuated resistance against arsenite-induced toxicity in mouse embryonic fibroblasts.	UBB UBC	1.90e-05	3	88	2	25701757
Pubmed	Interleukin 6 receptor alpha expression in PMNs isolated from prematurely born neonates: decreased expression is associated with differential mTOR signaling.	MTOR IL6R	1.90e-05	3	88	2	30965356
Pubmed	Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis.	MTOR FST	1.90e-05	3	88	2	20566686
Pubmed	Transient Receptor Potential C 1/4/5 Is a Determinant of MTI-101 Induced Calcium Influx and Cell Death in Multiple Myeloma.	TRPC4 TRPC5	1.90e-05	3	88	2	34199280
Pubmed	SREBF1 Activity Is Regulated by an AR/mTOR Nuclear Axis in Prostate Cancer.	MTOR SREBF1	1.90e-05	3	88	2	29784665
Pubmed	mTOR Driven Gene Transcription Is Required for Cholesterol Production in Neurons of the Developing Cerebral Cortex.	MTOR SREBF1	1.90e-05	3	88	2	34204880
Pubmed	The Ubiquitin Gene Expression Pattern and Sensitivity to UBB and UBC Knockdown Differentiate Primary 23132/87 and Metastatic MKN45 Gastric Cancer Cells.	UBB UBC	1.90e-05	3	88	2	32751694
Pubmed	Cumulative mutations of ubiquitin acceptor sites in human immunodeficiency virus type 1 gag cause a late budding defect.	UBB UBC	1.90e-05	3	88	2	16775314
Pubmed	Structure of tetraubiquitin shows how multiubiquitin chains can be formed.	UBB UBC	1.90e-05	3	88	2	8107144
Pubmed	Analysis of human immunodeficiency virus type 1 Gag ubiquitination.	UBB UBC	1.90e-05	3	88	2	15994808
Pubmed	TRPC1/4/5 channels contribute to morphine-induced analgesic tolerance and hyperalgesia by enhancing spinal synaptic potentiation and structural plasticity.	TRPC4 TRPC5	1.90e-05	3	88	2	32359120
Pubmed	Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain.	UBB UBC	1.90e-05	3	88	2	16543144
Pubmed	Perturbation of the hematopoietic system during embryonic liver development due to disruption of polyubiquitin gene Ubc in mice.	UBB UBC	1.90e-05	3	88	2	22393459
Pubmed	mTOR direct crosstalk with STAT5 promotes de novo lipid synthesis and induces hepatocellular carcinoma.	MTOR SREBF1	1.90e-05	3	88	2	31409773
Pubmed	Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels.	TRPC4 TRPC5	1.90e-05	3	88	2	28325835
Pubmed	Cellular senescence or EGFR signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR).	MTOR IL6R	1.90e-05	3	88	2	24047696
Pubmed	Overexpression of three ubiquitin genes in mouse epidermal tumors is associated with enhanced cellular proliferation and stress.	UBB UBC	1.90e-05	3	88	2	1321656
Pubmed	Dual action of the Gαq-PLCβ-PI(4,5)P2 pathway on TRPC1/4 and TRPC1/5 heterotetramers.	TRPC4 TRPC5	1.90e-05	3	88	2	30108272
Pubmed	Ubiquitin is covalently attached to the p6Gag proteins of human immunodeficiency virus type 1 and simian immunodeficiency virus and to the p12Gag protein of Moloney murine leukemia virus.	UBB UBC	3.79e-05	4	88	2	9525617
Pubmed	Interaction with dopamine D2 receptor enhances expression of transient receptor potential channel 1 at the cell surface.	TRPC4 TRPC5	3.79e-05	4	88	2	18261457
Pubmed	The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5.	TRPC4 TRPC5	3.79e-05	4	88	2	20164195
Pubmed	Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde.	UBB UBC	3.79e-05	4	88	2	12507430
Pubmed	Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes.	UBB UBC	3.79e-05	4	88	2	12354939
Pubmed	Human immunodeficiency virus type 1 Vif induces cell cycle delay via recruitment of the same E3 ubiquitin ligase complex that targets APOBEC3 proteins for degradation.	UBB UBC	3.79e-05	4	88	2	18596088
Pubmed	Requirements for the interaction of mouse Polkappa with ubiquitin and its biological significance.	UBB UBC	3.79e-05	4	88	2	18162470
Pubmed	Ubiquitination of HIV-1 and MuLV Gag.	UBB UBC	3.79e-05	4	88	2	11112487
Pubmed	The immunosuppressive properties of the HIV Vpr protein are linked to a single highly conserved residue, R90.	UBB UBC	3.79e-05	4	88	2	19516896
Pubmed	RalA functions as an indispensable signal mediator for the nutrient-sensing system.	RALGDS MTOR	3.79e-05	4	88	2	18948269
Pubmed	Late assembly domain function can exhibit context dependence and involves ubiquitin residues implicated in endocytosis.	UBB UBC	3.79e-05	4	88	2	11991975
Pubmed	Alpha-synuclein has an altered conformation and shows a tight intermolecular interaction with ubiquitin in Lewy bodies.	UBB UBC	3.79e-05	4	88	2	11603807
Pubmed	NMDA receptor-dependent synaptic activation of TRPC channels in olfactory bulb granule cells.	TRPC4 TRPC5	3.79e-05	4	88	2	22539836
Pubmed	Retroviruses have differing requirements for proteasome function in the budding process.	UBB UBC	3.79e-05	4	88	2	12610113
Pubmed	Transient Receptor Potential Canonical 5-Scramblase Signaling Complex Mediates Neuronal Phosphatidylserine Externalization and Apoptosis.	TRPC4 TRPC5	3.79e-05	4	88	2	32110987
Pubmed	TRPC5-induced autophagy promotes drug resistance in breast carcinoma via CaMKKβ/AMPKα/mTOR pathway.	MTOR TRPC5	3.79e-05	4	88	2	28600513
Pubmed	A role for ubiquitin ligase recruitment in retrovirus release.	UBB UBC	3.79e-05	4	88	2	11087860
Pubmed	Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2.	UBB UBC	3.79e-05	4	88	2	11087859
Pubmed	Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates.	UBB UBC	3.79e-05	4	88	2	12857950
Pubmed	Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms.	TRPC4 TRPC5	3.79e-05	4	88	2	23188715
Pubmed	Locus coeruleus neurons are resistant to dysfunction and degeneration by maintaining free ubiquitin levels although total ubiquitin levels decrease upon disruption of polyubiquitin gene Ubb.	UBB UBC	3.79e-05	4	88	2	22285186
Pubmed	Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication.	UBB UBC MCM5	3.90e-05	26	88	3	11931757
Pubmed	Formation of novel TRPC channels by complex subunit interactions in embryonic brain.	TRPC4 TRPC5	6.30e-05	5	88	2	12857742
Pubmed	Binding of HIV-1 Vpr protein to the human homolog of the yeast DNA repair protein RAD23 (hHR23A) requires its xeroderma pigmentosum complementation group C binding (XPCB) domain as well as the ubiquitin-associated 2 (UBA2) domain.	UBB UBC	6.30e-05	5	88	2	24318982
Pubmed	PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity.	UBB UBC	6.30e-05	5	88	2	24751536
Pubmed	Enhanced capacitative calcium entry and TRPC channel gene expression in human LES smooth muscle.	TRPC4 TRPC5	6.30e-05	5	88	2	12736151
Pubmed	Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis.	UBB UBC	6.30e-05	5	88	2	15466860
Pubmed	Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.	MTOR SREBF1	6.30e-05	5	88	2	22521878
Pubmed	Association of mammalian trp4 and phospholipase C isozymes with a PDZ domain-containing protein, NHERF.	TRPC4 TRPC5	6.30e-05	5	88	2	10980202
Pubmed	TRUSS, TNF-R1, and TRPC ion channels synergistically reverse endoplasmic reticulum Ca2+ storage reduction in response to m1 muscarinic acetylcholine receptor signaling.	TRPC4 TRPC5	6.30e-05	5	88	2	20458742
Pubmed	mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1.	GTF3C2 MTOR	6.30e-05	5	88	2	20543138
Pubmed	The role of viral and cellular proteins in the budding of human immunodeficiency virus.	UBB UBC	6.30e-05	5	88	2	16808324
Pubmed	Mutation of the Rb1 pathway leads to overexpression of mTor, constitutive phosphorylation of Akt on serine 473, resistance to anoikis, and a block in c-Raf activation.	MTOR RBL2	6.30e-05	5	88	2	19703998
Pubmed	Activation of a metabolic gene regulatory network downstream of mTOR complex 1.	MTOR SREBF1	6.30e-05	5	88	2	20670887
Pubmed	The atypical kinase Cdk5 is activated by insulin, regulates the association between GLUT4 and E-Syt1, and modulates glucose transport in 3T3-L1 adipocytes.	ESYT1 SLC2A4	6.30e-05	5	88	2	19255425
Pubmed	Calcium Channels Formed by Mammalian Trp Homologues.	TRPC4 TRPC5	9.43e-05	6	88	2	11390792
Pubmed	trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry.	TRPC4 TRPC5	9.43e-05	6	88	2	8646775
Pubmed	Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-Tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation.	UBB UBC	9.43e-05	6	88	2	16443603
Pubmed	TRPC channels regulate Ca2+-signaling and short-term plasticity of fast glutamatergic synapses.	TRPC4 TRPC5	9.43e-05	6	88	2	31536487
Pubmed	p62, a phosphotyrosine-independent ligand of the SH2 domain of p56lck, belongs to a new class of ubiquitin-binding proteins.	UBB UBC	9.43e-05	6	88	2	8702753
Pubmed	Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin.	MTOR FST	9.43e-05	6	88	2	22711699
Pubmed	A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics.	UBB UBC	9.43e-05	6	88	2	16874301
Pubmed	TRPM4 Conductances in Thalamic Reticular Nucleus Neurons Generate Persistent Firing during Slow Oscillations.	TRPC4 TRPC5	9.43e-05	6	88	2	32414784
Pubmed	The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2.	UBB UBC	9.43e-05	6	88	2	17290220
Interaction	TOP3B interactions	TYK2 FOCAD PALD1 SPG7 PELP1 TULP4 MTOR ESYT1 SCN5A SREBF1 OBSCN ARFGEF2 MCM5 FHIP1B TEP1 CHPF LYST ARHGEF10L ARAP1	3.50e-06	1470	80	19	int:TOP3B
GeneFamily	WD repeat domain containing	WDR38 GTF3C2 TULP4 TEP1 LYST RFWD3	1.71e-04	262	57	6	362
GeneFamily	Potassium voltage-gated channels	KCNG2 KCNA4 KCNH4	2.70e-04	40	57	3	274
GeneFamily	AAA ATPases	SPG7 LONP2 PEX1	6.22e-04	53	57	3	413
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ITSN2 OBSCN ARHGEF10L	1.18e-03	66	57	3	722
GeneFamily	Transient receptor potential cation channels	TRPC4 TRPC5	3.50e-03	28	57	2	249
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITSN2 TEP1 NIBAN3 LYST IL6R IER2	1.66e-06	182	88	6	f8c73baaaca145e2efc48f10f636feb79c8fc779
Disease	response to stress, systolic blood pressure change measurement	SPG7 MROH2A	8.15e-05	5	85	2	EFO_0006944, GO_0006950
Disease	arrhythmogenic right ventricular cardiomyopathy (is_marker_for)	SCN5A IL6R	1.71e-04	7	85	2	DOID:0050431 (is_marker_for)
Disease	Spastic Paraplegia	SPG7 LYST	2.91e-04	9	85	2	C0037772
Disease	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	TYK2 BCL11B MTOR	4.87e-04	53	85	3	C1961099
Disease	nicotine dependence (implicated_via_orthology)	TRPC4 TRPC5	5.31e-04	12	85	2	DOID:0050742 (implicated_via_orthology)
Disease	body mass index, type 2 diabetes mellitus	MTOR ARAP1	9.59e-04	16	85	2	EFO_0004340, MONDO_0005148
Disease	Non-Small Cell Lung Carcinoma	COL7A1 MXRA5 MTOR IL6R	1.09e-03	156	85	4	C0007131
Disease	type 2 diabetes mellitus (is_implicated_in)	MTOR SHBG SREBF1 SLC2A4	1.53e-03	171	85	4	DOID:9352 (is_implicated_in)
Disease	Lymphatic Metastasis	MTOR SHBG	2.55e-03	26	85	2	C0024232
Disease	obsessive-compulsive disorder, Tourette syndrome	TRPC4 LINC00587	2.55e-03	26	85	2	EFO_0004242, EFO_0004895

Protein segments in the cluster

Peptide	Gene	Start	Entry
LHGPQIGTLRLAMRR	MAMDC4	731	Q6UXC1
GMQLHGVLRVILEPL	ESYT1	236	Q9BSJ8
RLRSTAHLPGPLLSM	ARHGEF10L	1176	Q9HCE6
LGPGHLEMLRRTQSL	ADGRA1	506	Q86SQ6
GHELGMTPLQELSLR	ARFGEF2	546	Q9Y6D5
RILMVASHGLGLLGL	CLDN25	81	C9JDP6
GPTNCRLRMHLGLVI	ASPH	681	Q12797
DVIIGMPHRGRLNLL	DHTKD1	216	Q96HY7
MPHRGRLNLLTGLLQ	DHTKD1	221	Q96HY7
IGGTSMLPGFLHRLL	ACTR10	306	Q9NZ32
ARMALIGLGVSHPVL	UQCRC2	216	P22695
GLQRLHGMLEFLRPS	RFWD3	126	Q6PCD5
LLMNHRRGLGVDSKP	FAM107A	51	O95990
GPMTRRLLLHEVPTG	ITSN2	1666	Q9NZM3
GMDRLSHRLRQSPSG	NIBAN3	401	Q86XR2
LGMVLGTLILLHRSG	PALD1	321	Q9ULE6
LSRLHTMLTGLRNAP	RBL2	426	Q08999
MLVSEARQPLLRHGP	FHIP1B	136	Q8N612
SGLPRRVRTLMILHN	PODN	376	Q7Z5L7
IRPRTLLIEHLMEGG	EFCAB2	116	Q5VUJ9
LATGMRRGLLARPLN	H1-8	101	Q8IZA3
LLTHEGVLLPGSTMR	LONP2	16	Q86WA8
LLMVLRQASGRPHGS	GPAA1	291	O43292
PDGLTRRGDINLLML	MCM5	366	P33992
ARLVLPLGRLMHSGD	NPNT	466	Q6UXI9
RAGRRTLHLLGLAGM	SLC2A4	346	P14672
MGHRFLRGLLTLLLP	MYG1	1	Q9HB07
LARHSLGLRSLGLTM	KCNG2	301	Q9UJ96
TFLLSGIPGLERMHI	OR51G2	16	Q8NGK0
GSQLLRIRPGELQML	EPS8L3	556	Q8TE67
LRHIMGLLQARLGPP	KCNH4	901	Q9UQ05
SMPVRLLGHSPVLRN	CDC25B	151	P30305
MFSLEPRLRHLGLGK	DPP3	151	Q9NY33
MVRARHQPGGLCLLL	FST	1	P19883
LPGLMCLLRLHGSVG	PELP1	66	Q8IZL8
MARRLSGPLHTLGIP	KIF18B	596	Q86Y91
VRGPMHTLTLSGLRP	OBSCN	2126	Q5VST9
GMGRRLLLRSVQLHD	IL6R	76	P08887
SLNSGRLLHLAMRGL	GLP2R	496	O95838
LLRMTGPILRDHPGF	BCL11B	291	Q9C0K0
VTGPSQMDTRRGHLL	ETV7	146	Q9Y603
IIGLMSRLSPDGLRH	EDDM13	41	A0A1B0GTR0
RMQLGRLLVHILSPA	LYST	2741	Q99698
NMPGSDLERRAHLLL	RALGDS	231	Q12967
LRGHSLGSALRALMP	LINC02913	161	Q8NAJ2
SHDLGIILQRIRDMP	COL7A1	1111	Q02388
ELGEMRLRPTVLHSQ	LINC00587	46	B1AMM8
LGIVMARAISLGPHI	SLC38A11	136	Q08AI6
GRPLSRQLMSLVAGL	PEX1	576	O43933
LAPLLRHLGLTRMNI	FAM167B	141	Q9BTA0
LGLLHNRLSEAGLRM	NLRP6	761	P59044
LGRSPMHRVTLQEVL	FOCAD	1716	Q5VW36
EEPLGNARLHGARLM	PPP6R2	336	O75170
GGLRLHRSLQLSLVM	IER2	26	Q9BTL4
MLGHLVSNAPRLIRP	MTOR	756	P42345
LGDRHPSNLMLDRLS	MTOR	2336	P42345
LHSLMGRLQSRLSPR	MROH2A	1191	A6NES4
MGLDRPDVRAVLHLG	RECQL4	776	O94761
KLRSLVLAGIPHGMR	SGSM3	106	Q96HU1
DGPRAMNHLSLTRGL	SCN5A	501	Q14524
FMLGLRDGRPEIQLH	SHBG	96	P04278
LDGALMRPGRLDRHV	SPG7	461	Q9UQ90
FSLGPDLRLHEGTMR	TEX45	26	Q8NA69
LLRHLMPNSGSPIEL	OR8S1	256	Q8NH09
IGVPLEMVHGLLRIS	RHBDL1	271	O75783
HRVGRPDRGLSLSME	RBMXL2	341	O75526
LENMLGLLRHRGLRP	SLC39A5	301	Q6ZMH5
PEQRPSLHSRGMLDR	SREBF1	471	P36956
MLLPGHRRRILAGLL	ARAP1	51	Q96P48
LSRMLLQQLRPHLEG	CHPF	251	Q8IZ52
GHRDSRLLMASGPAL	TULP4	351	Q9NRJ4
LLTLGQLGRKRSRMH	AVPR1B	56	P47901
LGMDLLPPRHRLGAR	ZFR2	896	Q9UPR6
DTVQRLMLPHGRLSL	TEP1	1151	Q99973
LMLPHGRLSLVTGQS	TEP1	1156	Q99973
RGAGLRVTMHQPVLL	PRND	151	Q9UKY0
PGLRPQHLSGLEMIR	RTCA	46	O00442
STLHLVLRLRGGMQI	UBB	141	P0CG47
ETELHRMPVGGLLRN	ZNF621	106	Q6ZSS3
SGQMLRLLVGHRDSI	WDR38	136	Q5JTN6
EGGPQLSMLGLLRHI	SLC25A23	411	Q9BV35
MELLTLPHGRQLRLD	SH2D3C	621	Q8N5H7
VRGLASPLGHRMQLE	GTF3C2	866	Q8WUA4
MELILPSGARVGHRS	ZNF622	381	Q969S3
SHLGPLQISLGRMLL	TRPC5	501	Q9UL62
STLHLVLRLRGGMQI	UBC	141	P0CG48
ESTLHLVLRLRGGMQ	UBC	216	P0CG48
STLHLVLRLRGGMQI	UBC	521	P0CG48
ESTLHLVLRLRGGMQ	UBC	596	P0CG48
HLGPLQISLGRMLLD	TRPC4	501	Q9UBN4
PRLVMSIRDGIHGPL	TYK2	441	P29597
ILGHTLRASMRELGL	KCNA4	466	P22459
LPRLRSLTLHGNPME	LRRC51	126	Q96E66
GMHLEGPQTLGRVSL	MXRA5	2676	Q9NR99
AAGERHRMGRDPLLL	EXD3	11	Q8N9H8