Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K9me2/H3K9me3 demethylase activity

KDM4D KDM4A KDM4E KDM4B

5.64e-106514GO:0140684
GeneOntologyMolecularFunctionhistone H3K9 demethylase activity

KDM4D KDM4A KDM4E KDM4B

3.71e-0814514GO:0032454
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM4D KDM4A KDM4E TET3 KDM4B

6.54e-0765515GO:0016706
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM4D KDM4A KDM4E KDM4B

7.39e-0728514GO:0141052
GeneOntologyMolecularFunctionhistone demethylase activity

KDM4D KDM4A KDM4E KDM4B

1.13e-0631514GO:0032452
GeneOntologyMolecularFunctionprotein demethylase activity

KDM4D KDM4A KDM4E KDM4B

1.29e-0632514GO:0140457
GeneOntologyMolecularFunctiondemethylase activity

KDM4D KDM4A KDM4E KDM4B

4.75e-0644514GO:0032451
GeneOntologyMolecularFunctiondioxygenase activity

KDM4D KDM4A KDM4E TET3 KDM4B

5.05e-0698515GO:0051213
GeneOntologyMolecularFunctionA-type (transient outward) potassium channel activity

KCND2 KCND3

3.82e-054512GO:0005250
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

KDM4D KDM4A KDM4E TET3 KDM4B

1.34e-04194515GO:0016705
GeneOntologyMolecularFunctionhistone H3K36 demethylase activity

KDM4A KDM4B

3.47e-0411512GO:0051864
GeneOntologyMolecularFunctionphosphatidylinositol-5-phosphate binding

PLA2G4A WIPI2

1.56e-0323512GO:0010314
GeneOntologyMolecularFunctionoutward rectifier potassium channel activity

KCND2 KCND3

2.16e-0327512GO:0015271
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

KCNC3 KCND2 KCND3

2.26e-03102513GO:0005249
GeneOntologyCellularComponentpericentric heterochromatin

KDM4D KDM4A KDM4E KDM4B

1.16e-0632524GO:0005721
GeneOntologyCellularComponentvoltage-gated potassium channel complex

KCNC3 KCND2 KCND3 SLC5A3

7.75e-0591524GO:0008076
GeneOntologyCellularComponentheterochromatin

KDM4D KDM4A KDM4E KDM4B

1.16e-04101524GO:0000792
GeneOntologyCellularComponentpotassium channel complex

KCNC3 KCND2 KCND3 SLC5A3

1.30e-04104524GO:0034705
GeneOntologyCellularComponentdendritic spine

KCNC3 KCND2 KCND3 ADGRB1 GRID2

3.33e-04242525GO:0043197
GeneOntologyCellularComponentneuron spine

KCNC3 KCND2 KCND3 ADGRB1 GRID2

3.65e-04247525GO:0044309
GeneOntologyCellularComponentpostsynaptic membrane

KCNC3 KCND2 KCND3 ADGRB1 GRID2 CBLN1

4.89e-04405526GO:0045211
GeneOntologyCellularComponentplasma membrane protein complex

KCNC3 KCND2 IGHD KCND3 GRID2 CHUK TRAV14DV4 SLC5A3

6.64e-04785528GO:0098797
DomainJmjN

KDM4D KDM4A KDM4E KDM4B

8.68e-0910494SM00545
DomainJMJN

KDM4D KDM4A KDM4E KDM4B

8.68e-0910494PS51183
DomainJmjN

KDM4D KDM4A KDM4E KDM4B

8.68e-0910494PF02375
DomainJmjN

KDM4D KDM4A KDM4E KDM4B

8.68e-0910494IPR003349
DomainJmjC

KDM4D KDM4A KDM4E KDM4B

4.27e-0724494PF02373
DomainJMJC

KDM4D KDM4A KDM4E KDM4B

1.42e-0632494PS51184
DomainJmjC_dom

KDM4D KDM4A KDM4E KDM4B

1.42e-0632494IPR003347
DomainJmjC

KDM4D KDM4A KDM4E KDM4B

1.62e-0633494SM00558
DomainDUF3399

KCND2 KCND3

2.02e-053492PF11879
DomainK_chnl_volt-dep_Kv4

KCND2 KCND3

2.02e-053492IPR003975
DomainShal-type

KCND2 KCND3

2.02e-053492PF11601
DomainShal-type_N

KCND2 KCND3

2.02e-053492IPR021645
DomainK_chnl_volt-dep_Kv4_C

KCND2 KCND3

2.02e-053492IPR024587
DomainTUDOR

SMN1 KDM4A KDM4B

2.90e-0523493PS50304
DomainTUDOR

SMN1 KDM4A KDM4B

4.75e-0527493SM00333
DomainK_chnl_volt-dep_Kv

KCNC3 KCND2 KCND3

4.75e-0527493IPR003968
DomainTudor

SMN1 KDM4A KDM4B

6.55e-0530493IPR002999
DomainVG_K_chnl

KCNC3 KCND2 KCND3

8.76e-0533493IPR028325
DomainBTB_2

KCNC3 KCND2 KCND3

3.62e-0453493PF02214
DomainT1-type_BTB

KCNC3 KCND2 KCND3

3.62e-0453493IPR003131
DomainChannel_four-helix_dom

KCNC3 KCND2 KCND3

4.49e-0457493IPR027359
Domain-

KCNC3 KCND2 KCND3

4.49e-04574931.20.120.350
DomainLdl_recept_b

NID1 SORL1

6.01e-0414492PF00058
DomainLDLRB

NID1 SORL1

6.01e-0414492PS51120
DomainLY

NID1 SORL1

6.93e-0415492SM00135
DomainLDLR_classB_rpt

NID1 SORL1

6.93e-0415492IPR000033
DomainBTB

KCNC3 KCND2 KCND3 KLHL14

1.26e-03180494SM00225
DomainBTB/POZ_dom

KCNC3 KCND2 KCND3 KLHL14

1.39e-03185494IPR000210
DomainEPHD

KDM4A KDM4B

1.51e-0322492PS51805
DomainSKP1/BTB/POZ

KCNC3 KCND2 KCND3 KLHL14

1.51e-03189494IPR011333
DomainEGF_3

MALRD1 NID1 ADAM32 SORL1

3.32e-03235494PS50026
DomainEGF

MALRD1 NID1 ADAM32 SORL1

3.32e-03235494SM00181
DomainIon_trans_dom

KCNC3 KCND2 KCND3

3.33e-03114493IPR005821
DomainIon_trans

KCNC3 KCND2 KCND3

3.33e-03114493PF00520
DomainEGF-like_dom

MALRD1 NID1 ADAM32 SORL1

4.08e-03249494IPR000742
Domain-

NID1 SORL1

4.70e-03394922.120.10.30
DomainEGF-like_CS

MALRD1 NID1 ADAM32 SORL1

4.82e-03261494IPR013032
DomainLDLR_class-A_CS

MALRD1 SORL1

4.94e-0340492IPR023415
DomainEGF_2

MALRD1 NID1 ADAM32 SORL1

5.09e-03265494PS01186
DomainLdl_recept_a

MALRD1 SORL1

6.21e-0345492PF00057
Domain-

MALRD1 SORL1

6.48e-03464924.10.400.10
Domain6-blade_b-propeller_TolB-like

NID1 SORL1

6.48e-0346492IPR011042
DomainLDLRA_1

MALRD1 SORL1

7.04e-0348492PS01209
DomainLDLRA_2

MALRD1 SORL1

7.33e-0349492PS50068
DomainLDrepeatLR_classA_rpt

MALRD1 SORL1

7.33e-0349492IPR002172
DomainLDLa

MALRD1 SORL1

7.33e-0349492SM00192
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM4D KDM4A KDM4E KDM4B

1.13e-0629394MM14934
PathwayREACTOME_ACYL_CHAIN_REMODELING_OF_CL

PLA2G4A TAFAZZIN

7.42e-055392MM14576
PathwayREACTOME_ACYL_CHAIN_REMODELING_OF_CL

PLA2G4A TAFAZZIN

1.11e-046392M26958
PathwayREACTOME_PHASE_1_INACTIVATION_OF_FAST_NA_CHANNELS

KCND2 KCND3

1.55e-047392M27457
PathwayREACTOME_PHASE_1_INACTIVATION_OF_FAST_NA_CHANNELS

KCND2 KCND3

1.55e-047392MM15199
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNC3 KCND2 KCND3

1.94e-0441393MM14546
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNC3 KCND2 KCND3

2.24e-0443393M1056
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM4D KDM4A KDM4B

3.51e-0450393M27232
Pubmed

Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells.

KDM4D KDM4A KDM4E KDM4B

2.59e-11554416738407
Pubmed

Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family.

KDM4D KDM4A KDM4E KDM4B

2.59e-11554421914792
Pubmed

Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins.

KDM4D KDM4A KDM4E KDM4B

1.70e-091154419144645
Pubmed

The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice.

KDM4D KDM4A KDM4E

3.54e-09354321555854
Pubmed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

KDM4D KDM4A KDM4E KDM4B

3.05e-082154427626377
Pubmed

Identification and characterization of JMJD2 family genes in silico.

KDM4D KDM4A KDM4B

7.05e-08654315138608
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

KDM4D KDM4A KDM4E KDM4B

1.04e-064954434368113
Pubmed

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.

KDM4D KDM4A KDM4B

1.27e-061454316603238
Pubmed

New nomenclature for chromatin-modifying enzymes.

KDM4D KDM4A KDM4E KDM4B

1.93e-065754418022353
Pubmed

Histone Demethylase JMJD2D Interacts With β-Catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice.

KDM4D KDM4E

2.37e-06254230472235
Pubmed

Repressive histone methylation regulates cardiac myocyte cell cycle exit.

KDM4D KDM4E

2.37e-06254229800554
Pubmed

Dendritic Kv4.2 potassium channels selectively mediate spatial pattern separation in the dentate gyrus.

KCND2 KCND3

2.37e-06254234386734
Pubmed

Cbln1 is essential for synaptic integrity and plasticity in the cerebellum.

GRID2 CBLN1

2.37e-06254216234806
Pubmed

Cbln1 is a ligand for an orphan glutamate receptor delta2, a bidirectional synapse organizer.

GRID2 CBLN1

2.37e-06254220395510
Pubmed

Flap loop of GluD2 binds to Cbln1 and induces presynaptic differentiation.

GRID2 CBLN1

2.37e-06254220599760
Pubmed

Cbln1 downregulates the formation and function of inhibitory synapses in mouse cerebellar Purkinje cells.

GRID2 CBLN1

2.37e-06254224467251
Pubmed

Reader domain specificity and lysine demethylase-4 family function.

KDM4A KDM4B

2.37e-06254227841353
Pubmed

Isolation and characterization of the human gene encoding Ito: further diversity by alternative mRNA splicing.

KCND2 KCND3

2.37e-0625429843794
Pubmed

Strong KDM4B and KDM4D Expression Associates with Radioresistance and Aggressive Phenotype in Classical Hodgkin Lymphoma.

KDM4D KDM4B

2.37e-06254227630312
Pubmed

Differential expression of I(A) channel subunits Kv4.2 and Kv4.3 in mouse visual cortical neurons and synapses.

KCND2 KCND3

2.37e-06254217122053
Pubmed

Mutations in the genes KCND2 and KCND3 encoding the ion channels Kv4.2 and Kv4.3, conducting the cardiac fast transient outward current (ITO,f), are not a frequent cause of long QT syndrome.

KCND2 KCND3

2.37e-06254215563876
Pubmed

Demethylase JMJD2D induces PD-L1 expression to promote colorectal cancer immune escape by enhancing IFNGR1-STAT3-IRF1 signaling.

KDM4D KDM4E

2.37e-06254235027670
Pubmed

Embryonic development following somatic cell nuclear transfer impeded by persisting histone methylation.

KDM4D KDM4E

2.37e-06254225417163
Pubmed

Cbln1 and the δ2 glutamate receptor--an orphan ligand and an orphan receptor find their partners.

GRID2 CBLN1

2.37e-06254220535596
Pubmed

Kv4.3-Encoded Fast Transient Outward Current Is Presented in Kv4.2 Knockout Mouse Cardiomyocytes.

KCND2 KCND3

2.37e-06254226196737
Pubmed

Genomic organisation and chromosomal localisation of two members of the KCND ion channel family, KCND2 and KCND3.

KCND2 KCND3

2.37e-06254210942109
Pubmed

Kdm4d mutant mice show impaired sperm motility and subfertility.

KDM4D KDM4E

2.37e-06254239034148
Pubmed

Inflammation-induced JMJD2D promotes colitis recovery and colon tumorigenesis by activating Hedgehog signaling.

KDM4D KDM4E

2.37e-06254232094404
Pubmed

KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1.

KDM4A KDM4B

7.09e-06354226397136
Pubmed

Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D.

KDM4D KDM4A

7.09e-06354217555712
Pubmed

Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development.

KDM4A KDM4B

7.09e-06354227266524
Pubmed

Molecular dissection of I(A) in cortical pyramidal neurons reveals three distinct components encoded by Kv4.2, Kv4.3, and Kv1.4 alpha-subunits.

KCND2 KCND3

7.09e-06354220371829
Pubmed

Toll-like receptor 3 controls QT interval on the electrocardiogram by targeting the degradation of Kv4.2/4.3 channels in the endoplasmic reticulum.

KCND2 KCND3

7.09e-06354230758987
Pubmed

Role of heteromultimers in the generation of myocardial transient outward K+ currents.

KCND2 KCND3

7.09e-06354211909823
Pubmed

The histone demethylase JMJD2C is stage-specifically expressed in preimplantation mouse embryos and is required for embryonic development.

KDM4A KDM4B

7.09e-06354219696013
Pubmed

Histone demethylase JMJD2D protects against enteric bacterial infection via up-regulating colonic IL-17F to induce β-defensin expression.

KDM4D KDM4E

7.09e-06354238905308
Pubmed

Unique clustering of A-type potassium channels on different cell types of the main olfactory bulb.

KCND2 KCND3

7.09e-06354218371079
Pubmed

The testis-enriched histone demethylase, KDM4D, regulates methylation of histone H3 lysine 9 during spermatogenesis in the mouse but is dispensable for fertility.

KDM4D KDM4E

7.09e-06354221293030
Pubmed

Diversity within the JMJD2 histone demethylase family.

KDM4D KDM4A

7.09e-06354217207460
Pubmed

Comparative integromics on JMJD2A, JMJD2B and JMJD2C: preferential expression of JMJD2C in undifferentiated ES cells.

KDM4A KDM4B

7.09e-06354217611647
Pubmed

The KDM4/JMJD2 histone demethylases are required for hematopoietic stem cell maintenance.

KDM4A KDM4B

7.09e-06354231434704
Pubmed

I(A) channels encoded by Kv1.4 and Kv4.2 regulate neuronal firing in the suprachiasmatic nucleus and circadian rhythms in locomotor activity.

KCND2 KCND3

7.09e-06354222815518
Pubmed

A-type K+ channels encoded by Kv4.2, Kv4.3 and Kv1.4 differentially regulate intrinsic excitability of cortical pyramidal neurons.

KCND2 KCND3

7.09e-06354222615428
Pubmed

Gene structures and expression profiles of three human KCND (Kv4) potassium channels mediating A-type currents I(TO) and I(SA).

KCND2 KCND3

7.09e-06354210729221
Pubmed

Cbln1 accumulates and colocalizes with Cbln3 and GluRdelta2 at parallel fiber-Purkinje cell synapses in the mouse cerebellum.

GRID2 CBLN1

7.09e-06354219250438
Pubmed

GluD2- and Cbln1-mediated competitive interactions shape the dendritic arbors of cerebellar Purkinje cells.

GRID2 CBLN1

1.42e-05454233352118
Pubmed

TRIM14 inhibits OPTN-mediated autophagic degradation of KDM4D to epigenetically regulate inflammation.

KDM4D KDM4E

1.42e-05454235145029
Pubmed

The histone demethylase Kdm4 suppresses activation of hepatic stellate cell by inducing MiR-29 transcription.

KDM4A KDM4B

1.42e-05454231014673
Pubmed

GluRδ2 assembles four neurexins into trans-synaptic triad to trigger synapse formation.

GRID2 CBLN1

1.42e-05454222457515
Pubmed

Parvalbumin+ Neurons and Npas1+ Neurons Are Distinct Neuron Classes in the Mouse External Globus Pallidus.

KCND2 KCND3

1.42e-05454226311767
Pubmed

A synthetic synaptic organizer protein restores glutamatergic neuronal circuits.

GRID2 CBLN1

1.42e-05454232855309
Pubmed

Histone demethylase KDM4D cooperates with NFIB and MLL1 complex to regulate adipogenic differentiation of C3H10T1/2 mesenchymal stem cells.

KDM4D KDM4E

1.42e-05454232080306
Pubmed

Structural basis for integration of GluD receptors within synaptic organizer complexes.

GRID2 CBLN1

1.42e-05454227418511
Pubmed

Accessory Kvbeta1 subunits differentially modulate the functional expression of voltage-gated K+ channels in mouse ventricular myocytes.

KCND2 KCND3

1.42e-05454215662035
Pubmed

Isolation and characterization of rat skeletal muscle and cytoplasmic actin genes.

KDM4D KDM4E

1.42e-0545426953429
Pubmed

IA Channels Encoded by Kv1.4 and Kv4.2 Regulate Circadian Period of PER2 Expression in the Suprachiasmatic Nucleus.

KCND2 KCND3

1.42e-05454226152125
Pubmed

Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1.

KCND2 KCND3

1.42e-05454214980207
Pubmed

Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells.

KDM4A KDM4B

1.42e-05454227257215
Pubmed

Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM40 develop normally but show severe age-onset cataract formation and disruption of the lens.

COL4A2 NID1

2.36e-0555429524110
Pubmed

Kv4 potassium channels form a tripartite complex with the anchoring protein SAP97 and CaMKII in cardiac myocytes.

KCND2 KCND3

2.36e-05554219213956
Pubmed

Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum.

GRID2 CBLN1

2.36e-05554220537373
Pubmed

The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient.

KCND2 KCND3

2.36e-05554216239150
Pubmed

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.

KCNC3 KCND2 KCND3

3.36e-054054316382104
Pubmed

Interdependent roles for accessory KChIP2, KChIP3, and KChIP4 subunits in the generation of Kv4-encoded IA channels in cortical pyramidal neurons.

KCND2 KCND3

3.54e-05654220943905
Pubmed

Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein.

KDM4A KDM4B

3.54e-05654215927959
Pubmed

Targeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f).

KCND2 KCND3

3.54e-05654218603586
Pubmed

Nidogen-1. Expression and ultrastructural localization during the onset of mesoderm formation in the early mouse embryo.

COL4A2 NID1

4.94e-05754210639489
Pubmed

Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development.

KDM4A KDM4B

4.94e-05754221445275
Pubmed

Hypoplastic basement membrane of the lens anlage in the inheritable lens aplastic mouse (lap mouse).

COL4A2 NID1

4.94e-05754210716744
Pubmed

SMN1 functions as a novel inhibitor for TRAF6-mediated NF-κB signaling.

SMN1 CHUK

4.94e-05754228214532
Pubmed

Glycosylation of Cblns attenuates their receptor binding.

GRID2 CBLN1

4.94e-05754229782851
Pubmed

Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model.

KCND2 KCND3

4.94e-05754228646025
Pubmed

Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation.

KCNC3 KCND3 GRID2

5.12e-054654334815492
Pubmed

Compositional and structural requirements for laminin and basement membranes during mouse embryo implantation and gastrulation.

COL4A2 NID1

8.46e-05954215102706
Pubmed

Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis.

COL4A2 NID1

8.46e-0595428562707
Pubmed

Characterization of high affinity binding between laminin and the acute-phase protein, serum amyloid A.

COL4A2 NID1

8.46e-0595428995276
Pubmed

PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair.

KDM4D KDM4E

1.06e-041054224550317
Pubmed

Generation of a conditionally null allele of the laminin alpha1 gene.

COL4A2 NID1

1.06e-041054216100707
Pubmed

Beta1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex.

COL4A2 NID1

1.06e-041054211516395
Pubmed

Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development.

COL4A2 NID1

1.29e-041154214998921
Pubmed

Binding of mouse and human fibulin-2 to extracellular matrix ligands.

COL4A2 NID1

1.29e-04115427500359
Pubmed

Matrilin-2 interacts with itself and with other extracellular matrix proteins.

COL4A2 NID1

1.55e-041254212180907
Pubmed

Compound genetic ablation of nidogen 1 and 2 causes basement membrane defects and perinatal lethality in mice.

COL4A2 NID1

1.55e-041254216024816
Pubmed

Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.

COL4A2 NID1

1.83e-04135429833687
Pubmed

The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.

MALRD1 SLCO1B1

1.83e-041354211682476
Pubmed

Functional suppression of Kcnq1 leads to early sodium channel remodelling and cardiac conduction system dysmorphogenesis.

KCND2 KCND3

2.13e-041454223542581
Pubmed

cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein.

MAOA SULT1A1

2.45e-04155421741163
Pubmed

Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.

COL4A2 NID1

2.45e-041554210625553
Pubmed

Neuronal interleukin-16 (NIL-16): a dual function PDZ domain protein.

KCND2 KCND3

2.45e-041554210479680
Pubmed

Secreted IgD Amplifies Humoral T Helper 2 Cell Responses by Binding Basophils via Galectin-9 and CD44.

IGHD SMN1

2.80e-041654230291028
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

COL4A2 NID1

2.80e-041654215878328
Pubmed

Molecular genetics of hereditary spinocerebellar ataxia: mutation analysis of spinocerebellar ataxia genes and CAG/CTG repeat expansion detection in 225 Italian families.

KCNC3 KCND3

3.17e-041754215148151
Pubmed

Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.

MAGED2 NID1 NCAPH

3.78e-049054328535371
Pubmed

Hereditary Ataxia Overview

KCNC3 KCND3 GRID2

4.03e-049254320301317
Pubmed

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites.

KDM4A KDM4B

4.42e-042054222373579
Pubmed

Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition.

SULT1A1 SLCO1B1

4.42e-042054221072184
Pubmed

Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin.

KDM4A KDM4B

5.36e-042254228963472
Pubmed

Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly.

NID1 SORL1

5.36e-042254218448648
Pubmed

Cbln1 regulates axon growth and guidance in multiple neural regions.

GRID2 CBLN1

5.36e-042254236395107
Pubmed

Comparative FISH mapping of mouse and rat homologues of twenty-five human X-linked genes.

MAOA TAFAZZIN

6.39e-04245429730605
Cytoband14q32.33

IGHD IGHV1-46 IGHV7-4-1 IGHV7-81

1.66e-0422855414q32.33
CytobandEnsembl 112 genes in cytogenetic band chr14q32

MOK IGHD IGHV1-46 IGHV7-4-1 IGHV7-81

5.86e-04566555chr14q32
Cytoband11q21

KDM4D KDM4E

1.29e-034455211q21
CytobandEnsembl 112 genes in cytogenetic band chr11q21

KDM4D KDM4E

2.63e-0363552chr11q21
GeneFamilyPHD finger proteins|Lysine demethylases

KDM4D KDM4A KDM4E KDM4B

1.71e-0724384485
GeneFamilyTudor domain containing

SMN1 KDM4A KDM4B

6.34e-0537383780
GeneFamilyPotassium voltage-gated channels

KCNC3 KCND2 KCND3

8.02e-0540383274
GeneFamilyImmunoglobulin heavy locus at 14q32.33

IGHD IGHV1-46 IGHV7-4-1 IGHV7-81

6.21e-04187384349
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000

MYH3 TINAG PRRX1 SULT1A1 KCND3 FRMPD2 NID1 KLHL14 WIPI2 SLC5A3

1.14e-057974910gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_500

MYH3 TINAG PRRX1 KCND3 FRMPD2 NID1 SLC5A3

3.20e-05395497gudmap_developingGonad_P2_epididymis_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_100

CPA6 MYH3 PRRX1 GRID2

4.62e-0586494gudmap_developingLowerUrinaryTract_e14.5_ urethra_100
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

COL4A2 PRRX1 KCND2 KCND3 SV2A PLA2G4A NID1 CBLN1 FGF18

6.20e-05777499gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000

TINAG PRRX1 MAOA KCND2 KCND3 FRMPD2 NID1 WIPI2 SLC5A3

7.04e-05790499gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlasdev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_1000

MAOA ACADSB KCND2 PLA2G4A

7.41e-0597494gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k2_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

PRRX1 KCND2 PLA2G4A NID1 CBLN1 FGF18

1.75e-04361496gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#5_top-relative-expression-ranked_500

MYH3 TINAG KCND3 FRMPD2

1.80e-04122494gudmap_developingGonad_P2_epididymis_500_k5
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#2_top-relative-expression-ranked_1000

MYH3 TINAG KCND3 FRMPD2 KLHL14

1.85e-04230495gudmap_developingGonad_P2_epididymis_1000_k2
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

CPA6 NWD1 KCND2 GRID2 SEL1L2

1.56e-061595555335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACADSB SV2A RPS6KA6 KLHL14 SLC5A3

3.11e-0618355503c7e69136d5a3b9c5b2c91733e9b1c791f45c49
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 KCND3 NID1 GRID2 FGF18

3.28e-061855559faa35ceb89ccd2979072286f063687c9f846ce3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 CPA6 PRRX1 PLA2G4A NID1

3.64e-06189555c734e5693808a0333139e87bd5be2597a9252afe
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACADSB SV2A RPS6KA6 SORL1 SLC5A3

3.73e-0619055568ba1934b2b3f0cec8efd229fe1db6e8be8a26b0
ToppCelldroplet-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRRX1 KCND3 NID1 GRID2 FGF18

3.73e-061905552abeb013bb83c578e67dcb985ba44ca63134950b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 CPA6 PRRX1 PLA2G4A NID1

3.73e-061905552e592323085ba9c019d678ac2a784462ab470ed9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 CPA6 PRRX1 PLA2G4A NID1

3.73e-06190555445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACADSB SV2A RPS6KA6 SORL1 SLC5A3

3.73e-06190555010d7d13a3c16e614c36720ef690a505b9f3f7aa
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 CPA6 PRRX1 PLA2G4A NID1

3.83e-06191555c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 CPA6 PRRX1 PLA2G4A NID1

3.83e-061915551caf726bd07fdca389e678fc16304a6ef1790423
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 CPA6 PRRX1 PLA2G4A NID1

3.83e-06191555806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 CPA6 PRRX1 PLA2G4A NID1

3.83e-06191555cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 CPA6 PRRX1 PLA2G4A NID1

3.83e-061915553d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 CPA6 PRRX1 PLA2G4A NID1

3.93e-061925554022f208eb5db760abd0aac782a25e8ab63efc64
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 CPA6 PRRX1 PLA2G4A NID1

3.93e-061925559333aba0d04203ccccad78d82bf6359922f810a7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRRX1 KCND2 KCND3 PLA2G4A GRID2

4.24e-061955553c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-9|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGHD IGHV1-46 RPS6KA6 KLHL14

3.64e-051515542314c004434aed9b7fa1ad01c61c43e5ed4a18ce
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Grm1-Inhibitory_Neuron.Gad1Gad2_Sst.Grm1_(Interneuron,_OLM3_(CA1_enriched?))-|Hippocampus / BrainAtlas - Mouse McCarroll V32

TINAG ADAM32 KLHL14

4.34e-055555310e98fc862d89141512bdebae1231ef1a82105b0
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Grm1-Inhibitory_Neuron.Gad1Gad2_Sst.Grm1_(Interneuron,_OLM3_(CA1_enriched?))|Hippocampus / BrainAtlas - Mouse McCarroll V32

TINAG ADAM32 KLHL14

4.34e-0555553a55d3edca2dd9ca7a703b2b3a5941b30b5f0a6df
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Grm1|Hippocampus / BrainAtlas - Mouse McCarroll V32

TINAG ADAM32 KLHL14

4.34e-0555553bac333ea3914a49376105dd977a0b8493b0d2001
ToppCell356C-Fibroblasts-Fibroblast-H-|356C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 PRRX1 SV2A TRAV14DV4

5.51e-05168554b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCell356C-Fibroblasts-Fibroblast-H|356C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 PRRX1 SV2A TRAV14DV4

5.51e-05168554838ce47d4958ba12047882f97925eddd02f081c7
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-Pre-B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHD IGHV7-4-1 IGHV7-81 KLHL14

6.90e-0517855434ef4d36ddfb1cdeaaaf5d952e1ad6dc2785ce1e
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPA6 PRRX1 KCND2 FGF18

7.21e-051805543d95232b5785c705f41e01e3ffe0fa8dce1ff0a7
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 PRRX1 PLA2G4A NID1

7.21e-05180554280ff5c8f292be1b88120db5ff1788b750644856
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 PRRX1 PLA2G4A NID1

7.21e-05180554fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACADSB RPS6KA6 SORL1 SLC5A3

7.21e-051805540b653b1b653b40f3b8711d1312029a4a8a4961db
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPA6 PRRX1 KCND2 FGF18

7.21e-0518055447e345359064dc8ceec982b062e47802e728b43f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 PRRX1 LINC02898 NID1

7.36e-05181554c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 PRRX1 LINC02898 NID1

7.36e-05181554c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellPericytes-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 SV2A NID1 SEL1L2

7.68e-05183554d04deef7cd4e1738227a6593b84874ce0168c773
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRRX1 KCND2 KCND3 NID1

7.85e-05184554e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 PRRX1 KCND2 NID1

8.18e-051865547582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 ELSPBP1 CBLN1 SLC5A3

8.35e-051875549225caf66e06ebe57e90d677122acb6498607f36
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACADSB SV2A RPS6KA6 SLC5A3

8.52e-0518855414e120b20e76baa07b6510a94f0c2dcdfdd52357
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACADSB SV2A RPS6KA6 SLC5A3

8.70e-05189554443359d90fafae0c1de6bdcce9e8c95df6ea4de8
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 SULT1A1 MAGED2 NID1

8.88e-051905541004e89d99c9d46c78b7d3532d8d4aadb81a96fd
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRRX1 KCND3 NID1 FGF18

8.88e-05190554f61e21d53f2f7804ac6e40ab6c7f69838aa94d6a
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACADSB RPS6KA6 SORL1 SLC5A3

8.88e-05190554c247562df3e1aa3173c9f01a74d5831f0764a1b2
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACADSB RPS6KA6 SORL1 SLC5A3

8.88e-051905545cea8298c8336c136ba009630c9e48d4bc832cb2
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACADSB SV2A RPS6KA6 SLC5A3

9.06e-051915545a5b5402a077b3189ca156f2bac5f47ad780aebf
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACADSB SV2A RPS6KA6 SLC5A3

9.06e-0519155478bcce497920cc5b3bef083eab50deb1cc82cd2e
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACADSB RPS6KA6 SORL1 SLC5A3

9.06e-05191554297bc79adc5fef211497819b4861b52cd26ac754
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACADSB RPS6KA6 SORL1 SLC5A3

9.06e-05191554e1ec165ba6578cefd88895e7e183190e79f733a4
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRRX1 NID1 GRID2 FGF18

9.06e-05191554d1205aab0937f2becfcd239610e9b78fb8a0c886
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACADSB RPS6KA6 SORL1 SLC5A3

9.25e-05192554e19e3e8edcc08e4a67873bfb6e46489ca6c8756a
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACADSB RPS6KA6 SORL1 SLC5A3

9.25e-0519255461c2caf6c838132ed5faa8791c288f2149eba2c8
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 SULT1A1 MAGED2 NID1

9.25e-05192554158cc5736f154da1cb3186ffbf186eae10483e48
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 SULT1A1 MAGED2 NID1

9.25e-05192554f4ff62ac9c53eafbe917706de9af8b2d4bded4d4
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A2 PRRX1 MAGED2 NID1

9.62e-051945546a4e7f1bf67bad94cd8c472e7c66798b0c25ba01
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRRX1 KCND2 KCND3 GRID2

9.62e-05194554c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A2 PRRX1 KCND2 NID1

9.62e-051945542d66091097e106c7bee22e5281f50724700bdf8d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 PRRX1 PLA2G4A NID1

9.62e-0519455490efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 PRRX1 PLA2G4A NID1

9.62e-05194554df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL4A2 PRRX1 PLA2G4A NID1

9.82e-051955543d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell15-Trachea-Mesenchymal|Trachea / Age, Tissue, Lineage and Cell class

COL4A2 PRRX1 NID1 FGF18

1.00e-041965547e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 PRRX1 NID1 CBLN1

1.02e-04197554cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 PRRX1 PLA2G4A NID1

1.02e-0419755409946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL4A2 MAOA KCND3 NID1

1.02e-041975543bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL4A2 MAOA KCND3 NID1

1.02e-0419755417344464fdcc5ba0c03959696b97c195f11e644c
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL4A2 MAOA KCND3 NID1

1.02e-041975545b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCellnormal_Lung-Endothelial_cells-Tip-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

COL4A2 MAOA SULT1A1 MAGED2

1.06e-0419955472c96a5954dfcfbfee8f095984ce1f5249d9a679
ToppCellCOVID-19-kidney-Fibroblast-1|kidney / Disease (COVID-19 only), tissue and cell type

COL4A2 PRRX1 PLA2G4A NID1

1.06e-041995549503646ff1ad248181146ce767e9d12e882ec3bd
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 PRRX1 KCND2 NID1

1.08e-04200554ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 PRRX1 KCND2 NID1

1.08e-042005540c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellControl-B_naive-11|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

IGHD FRMPD2 CLEC10A

5.06e-04126553319a4c325e0e5c14bb49a143b8924c554f834cc0
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_7|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MALRD1 FRMPD2 CLEC10A

6.59e-04138553c172880eda7b8b8b758dbbc77f93191238f3181c
ToppCellControl-B_naive-11|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

IGHD FRMPD2 CLEC10A

6.73e-041395532af7ad44b707d139c6f055e63d68c09b5c1bb1be
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

MALRD1 GRID2 SEL1L2

6.73e-0413955364c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_7|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MALRD1 FRMPD2 CLEC10A

6.73e-04139553313f7e66ed94950129c7146a2afe2feb8951fe1e
ToppCellfacs-Marrow-B-cells-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRID2 CLEC10A CBLN1

7.31e-041435536df16bf0324661cd9707df69cb39f4b5498d6d49
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-tDC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

KCNC3 RPS6KA6 CLEC10A

7.61e-04145553a6c291811bf62f1c13f1b4b396d75c2223cf1c7d
ToppCellfacs-Marrow-B-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRID2 CLEC10A CBLN1

7.92e-041475539d7e965fe61bd7b31e09c4b2129a5a98c36f4811
ToppCellfacs-Marrow-B-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRID2 CLEC10A CBLN1

7.92e-0414755338552953ff65a0fc20bee6ef57dc5885306ad18b
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|343B / Donor, Lineage, Cell class and subclass (all cells)

DISP2 NCAPH TAFAZZIN

8.23e-041495532a7f71da51c85e04de2123164914122480e60d66
ToppCell356C-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SV2A SMN1 TRAV14DV4

8.55e-041515532dc132895609e4efe17954e31f53d9c1ccf256ef
ToppCell356C-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SV2A SMN1 TRAV14DV4

8.55e-0415155322afd8201eff8471da3456be065f2790de5e4bfe
ToppCell368C-Fibroblasts-Fibroblast-H-|368C / Donor, Lineage, Cell class and subclass (all cells)

PRRX1 MALRD1 MID2

8.72e-04152553dbfb4d4de36ef9f5c7da1950baa915b12788685e
ToppCellTransplant_Alveoli_and_parenchyma-Immune-B_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

IGHD FRMPD2 KLHL14

8.72e-0415255366f9190de155251a63a7a669374f342a75d22ea0
ToppCell368C-Fibroblasts-Fibroblast-H|368C / Donor, Lineage, Cell class and subclass (all cells)

PRRX1 MALRD1 MID2

8.72e-041525539f3682da00fd627e80aa820ecc6f5fed23b9738a
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IGHD ADGRB1 KLHL14

9.40e-041565534e4b94580969a9736ca28df79715535a4bd1f9b2
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MOK KCNC3 CLEC10A

9.57e-04157553f896997490bb2eec598c6581f161220e70f9a991
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MOK KCNC3 CLEC10A

9.57e-0415755314a8516346a89a89f1119b744625bd9844a74a03
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic-6|TCGA-Mesothelium / Sample_Type by Project: Shred V9

COL4A2 NID1 NCAPH

9.93e-0415955385501c636cd04f15ba1be24df1ba7ac909633ce8
ToppCellnormal_Lung-B_lymphocytes-MALT_B_cells|normal_Lung / Location, Cell class and cell subclass

IGHD IGHV1-46 KLHL14

9.93e-04159553fbd0131b66f4267f7b0d6c3ad874ad097b859074
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NWD1 MALRD1 KLHL14

1.01e-0316055303b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCell368C-Fibroblasts-Fibroblast-E|368C / Donor, Lineage, Cell class and subclass (all cells)

PRRX1 SV2A RPS6KA6

1.05e-03162553e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell368C-Fibroblasts-Fibroblast-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

PRRX1 SV2A RPS6KA6

1.05e-03162553ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCell10x3'2.3-week_14-16-Lymphocytic_B-B_lineage-immature_B_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

IGHD KLHL14 KDM4B

1.09e-0316455369b6566fb88c7449b7ab9056b57508cb6a1aa2af
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MOK DISP2 GRID2

1.09e-03164553fe11fcce4ba7f44ba2989ea3705916b67e75f8e7
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MOK DISP2 GRID2

1.09e-03164553b6beb8548ac0dd07e8a580a938e5ee4bf25a3c1f
ToppCellnormal_Lung-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

CLEC10A NCAPH SORL1

1.12e-0316655307b498eb341abec02a3ccaae320bdbb5cd6883c5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NWD1 GRID2 SEL1L2

1.14e-031675533edb0570e583bb527165bcd8a4c25a042054043b
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRRX1 KCND2 KCND3

1.14e-03167553e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCellControl-Myeloid-MoAM1,_IL1R2|Control / Condition, Lineage and Cell class

CPA6 MYH3 CLEC10A

1.14e-03167553ab6029ba037b6a499da8758864c44e174cde5587
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRRX1 NID1 FGF18

1.18e-03169553bb43abad2c049b7f4d307737347290e01b3339a3
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRRX1 NID1 FGF18

1.18e-031695535f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRRX1 NID1 FGF18

1.18e-031695538bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FGF18 KDM4B SORL1

1.20e-03170553ba4ba66b624089ed50a9083176386c7941b4c7a3
DiseaseSudden Cardiac Arrest

KCND2 KCND3

8.47e-058522C1720824
Diseaseinterleukin 12 measurement

KCNC3 GRID2 ADAM32

1.14e-0453523EFO_0004753
Diseasealopecia areata (is_marker_for)

KDM4A KDM4B

1.36e-0410522DOID:986 (is_marker_for)
Diseasetaurolithocholate 3-sulfate measurement

PLA2G4A SLCO1B1

2.35e-0413522EFO_0021036
DiseaseArthrogryposis

MYH3 SMN1

6.26e-0421522C0003886
Diseasetonsillectomy risk measurement

PRRX1 SULT1A1 SV2A SLCO1B1

1.14e-03260524EFO_0007924
DiseaseAutistic Disorder

MAOA ACADSB KCND2 PLA2G4A

1.16e-03261524C0004352
DiseaseMovement Disorders

TET3 TSEN2

1.20e-0329522C0026650
DiseaseMyopathy

MAOA SLCO1B1

1.28e-0330522C0026848
Diseasecardiac arrhythmia

PRRX1 KCND3

1.28e-0330522EFO_0004269
Diseasecaudate nucleus volume

MOK TSEN2

1.28e-0330522EFO_0004830
Diseasebitter alcoholic beverage consumption measurement

KCND2 TET3 SORL1

1.68e-03133523EFO_0010092

Protein segments in the cluster

PeptideGeneStartEntry
FTKAKGYSTMNYCWL

ADGRB1

1071

O14514
VGMNKLWSGYSLLYF

COL4A2

1506

P08572
GDYYVLNGSKMWISS

ACADSB

196

P45954
KTLYDYWGSDSMIVT

ADAM32

196

Q8TC27
YVSSGSSMDWAYKNG

CPA6

376

Q8N4T0
YAKLVFMSTSSGSLW

DISP2

286

A7MBM2
KWKFEMSYTSSYCRG

NWD1

1421

Q149M9
MSAASDLYGSWKFGY

RRH

81

O14718
FFAGTETATKWSGYM

MAOA

431

P21397
ASFWYTIVTMTTLGY

KCND3

356

Q9UK17
CKASGYSFTTYGMNW

IGHV7-81

41

A0A0B4J1V7
FFWGLRSYYETSKMK

MAGED2

441

Q9UNF1
CKASGYTFTSYYMHW

IGHV1-46

41

P01743
KPYTATVDYWSFGTM

CHUK

196

O15111
TSTTLYNSMWFVYGS

GRID2

601

O43424
VTSYGKNLYFTDWKM

NID1

1156

P14543
LMSAKYSGWYVGFTK

FGF18

141

O76093
VNTPYLYFGMWKTSF

KDM4A

171

O75164
GVNTPYLYFGMWKTT

KDM4B

171

O94953
NTPYLYFGMWKTTFA

KDM4D

176

Q6B0I6
FWYTIVTMTTLGYGD

KCND2

361

Q9NZV8
GVNTPYLYFGMWKTT

KDM4E

171

B2RXH2
WSLGVLFYTMLAGYT

RPS6KA6

606

Q9UK32
DGFYTYKMDLWSAGC

MOK

176

Q9UQ07
CKASGYTFTSYAMNW

IGHV7-4-1

41

A0A0J9YVY3
MSFWYFVSAKATGSI

MALRD1

1596

Q5VYJ5
GGYSWSMGAYKSSTI

KLHL14

576

Q9P2G3
LMGGWKYSTFSGFLV

CBLN1

176

P23435
VYSLGMTLYWSAGFH

FRMPD2

106

Q68DX3
TGYHPTSVTVTWYMG

IGHD

31

P01880
SYFWNSSKGVYMSGS

LINC02898

116

Q6ZV80
WTTFLLYSYESSGGM

ELSPBP1

11

Q96BH3
TWTYSFSGAFLFSMG

IL22RA1

226

Q8N6P7
ATYVAGLSGSTWYMS

PLA2G4A

221

P47712
GLSGSTWYMSTLYSH

PLA2G4A

226

P47712
TTYMAYHYFRSKGWV

TSEN2

341

Q8NCE0
YIVEYSRSGSKMWAS

SORL1

1686

Q92673
MYYSGSGIWKDYKLA

SEL1L2

416

Q5TEA6
FAMWKSNRSTVSGYF

SLC5A3

26

P53794
GSMLISWYMSGYHTG

SMN1

261

Q16637
TSWMIYTYSGLFCVT

MYH3

111

P11055
WTGYFGKVLMASTSY

WIPI2

291

Q9Y4P8
GCLKESGSYMWIYVF

SLCO1B1

161

Q9Y6L6
MGVWFTMSFSYYGLT

SV2A

451

Q7L0J3
NFVQKYLGSAYTWMG

CLEC10A

226

Q8IUN9
GEYSYFSPRTMSMWA

NCAPH

426

Q15003
KIRGMKWYSSFIGYV

PGBD2

476

Q6P3X8
GLVGTYSCFWTKYMN

TAFAZZIN

26

Q16635
KFMVGEVSYGSWYQH

SULT1A1

161

P50225
WSMYFNGCKYARSKT

TET3

986

O43151
SYGLFWYKQPSSGEM

TRAV14DV4

51

A0A0A6YYC5
KMAGFYGLYTWLTHT

TMEM245

716

Q9H330
MWTGYKILIFSYLTT

TINAG

1

Q9UJW2
VMGSSTWYAIGIAYK

MID2

596

Q9UJV3
LSWGTASPYSAMATY

PRRX1

191

P54821
WAVVTMTTLGYGDMY

KCNC3

496

Q14003