Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytidine deaminase activity

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.60e-0913264GO:0004126
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

NDST4 NDST1 APOBEC3C APOBEC3D APOBEC3B APOBEC3F

2.81e-08146266GO:0016810
GeneOntologyMolecularFunctiondeaminase activity

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.02e-0734264GO:0019239
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.29e-0736264GO:0016814
GeneOntologyMolecularFunction[heparan sulfate]-glucosamine N-sulfotransferase activity

NDST4 NDST1

9.77e-064262GO:0015016
GeneOntologyMolecularFunctionN-acetylglucosamine deacetylase activity

NDST4 NDST1

9.77e-064262GO:0050119
GeneOntologyMolecularFunctionsodium channel inhibitor activity

NEDD4L NEDD4

4.54e-058262GO:0019871
GeneOntologyMolecularFunctiontrace-amine receptor activity

TAAR9 TAAR1

4.54e-058262GO:0001594
GeneOntologyMolecularFunctionheparan sulfate sulfotransferase activity

NDST4 NDST1

1.69e-0415262GO:0034483
GeneOntologyMolecularFunctiondeacetylase activity

NDST4 NDST1

1.23e-0340262GO:0019213
GeneOntologyMolecularFunctionG protein-coupled amine receptor activity

TAAR9 TAAR1

1.30e-0341262GO:0008227
GeneOntologyMolecularFunctionsodium channel regulator activity

NEDD4L NEDD4

1.49e-0344262GO:0017080
GeneOntologyMolecularFunctionthiolester hydrolase activity

ABHD13 CLN5

1.70e-0347262GO:0016790
GeneOntologyMolecularFunctionion channel inhibitor activity

NEDD4L NEDD4

1.77e-0348262GO:0008200
GeneOntologyMolecularFunctionchannel inhibitor activity

NEDD4L NEDD4

1.92e-0350262GO:0016248
GeneOntologyMolecularFunctiontransporter inhibitor activity

NEDD4L NEDD4

2.00e-0351262GO:0141110
GeneOntologyMolecularFunctionsulfotransferase activity

NDST4 NDST1

2.32e-0355262GO:0008146
GeneOntologyMolecularFunctiontransition metal ion binding

APOBEC3C APOBEC3D UPF1 MIOX APOBEC3B APOBEC3F

3.62e-031189266GO:0046914
GeneOntologyMolecularFunctiontransferase activity, transferring sulphur-containing groups

NDST4 NDST1

4.16e-0374262GO:0016782
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

NDST4 NDST1

4.96e-0381262GO:0016811
GeneOntologyMolecularFunctionzinc ion binding

APOBEC3C APOBEC3D UPF1 APOBEC3B APOBEC3F

5.26e-03891265GO:0008270
GeneOntologyBiologicalProcessclearance of foreign intracellular DNA

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

2.97e-116264GO:0044355
GeneOntologyBiologicalProcessclearance of foreign intracellular nucleic acids

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

2.97e-116264GO:0099046
GeneOntologyBiologicalProcessDNA cytosine deamination

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

4.14e-1010264GO:0070383
GeneOntologyBiologicalProcesscytidine to uridine editing

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

9.75e-1012264GO:0016554
GeneOntologyBiologicalProcesscytidine metabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.97e-0914264GO:0046087
GeneOntologyBiologicalProcesscytidine catabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.97e-0914264GO:0006216
GeneOntologyBiologicalProcesscytidine deamination

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.97e-0914264GO:0009972
GeneOntologyBiologicalProcessDNA deamination

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.97e-0914264GO:0045006
GeneOntologyBiologicalProcessnegative regulation of single stranded viral RNA replication via double stranded DNA intermediate

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

3.57e-0916264GO:0045869
GeneOntologyBiologicalProcesspyrimidine ribonucleoside metabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

3.57e-0916264GO:0046131
GeneOntologyBiologicalProcesspyrimidine ribonucleoside catabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

3.57e-0916264GO:0046133
GeneOntologyBiologicalProcesspyrimidine nucleoside catabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

6.00e-0918264GO:0046135
GeneOntologyBiologicalProcessregulation of single stranded viral RNA replication via double stranded DNA intermediate

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

7.59e-0919264GO:0045091
GeneOntologyBiologicalProcessbase conversion or substitution editing

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

7.59e-0919264GO:0016553
GeneOntologyBiologicalProcesssingle stranded viral RNA replication via double stranded DNA intermediate

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

9.48e-0920264GO:0039692
GeneOntologyBiologicalProcessribonucleoside catabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

2.91e-0826264GO:0042454
GeneOntologyBiologicalProcesspyrimidine nucleoside metabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

3.41e-0827264GO:0006213
GeneOntologyBiologicalProcessDNA modification

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

6.10e-0831264GO:0006304
GeneOntologyBiologicalProcessviral RNA genome replication

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

6.96e-0832264GO:0039694
GeneOntologyBiologicalProcessnucleoside catabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

6.96e-0832264GO:0009164
GeneOntologyBiologicalProcessnucleobase-containing small molecule catabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.27e-0737264GO:0034656
GeneOntologyBiologicalProcessglycosyl compound catabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.95e-0741264GO:1901658
GeneOntologyBiologicalProcesspyrimidine-containing compound catabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

3.12e-0746264GO:0072529
GeneOntologyBiologicalProcesstransposable element silencing

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

3.12e-0746264GO:0010526
GeneOntologyBiologicalProcessribonucleoside metabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

3.72e-0748264GO:0009119
GeneOntologyBiologicalProcessretrotransposition

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

3.72e-0748264GO:0032197
GeneOntologyBiologicalProcesstransposition

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

4.39e-0750264GO:0032196
GeneOntologyBiologicalProcessnegative regulation of viral genome replication

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

6.97e-0756264GO:0045071
GeneOntologyBiologicalProcessnucleoside metabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.53e-0668264GO:0009116
GeneOntologyBiologicalProcessregulation of viral genome replication

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

4.92e-0691264GO:0045069
GeneOntologyBiologicalProcesspyrimidine-containing compound metabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

5.14e-0692264GO:0072527
GeneOntologyBiologicalProcessglycosyl compound metabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

6.09e-0696264GO:1901657
GeneOntologyBiologicalProcessnegative regulation of viral process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

8.06e-06103264GO:0048525
GeneOntologyBiologicalProcessviral genome replication

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

2.49e-05137264GO:0019079
GeneOntologyBiologicalProcessregulation of viral life cycle

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

4.13e-05156264GO:1903900
GeneOntologyBiologicalProcessheparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

NDST4 NDST1

4.26e-058262GO:0015014
GeneOntologyBiologicalProcessviral life cycle

APOBEC3C APOBEC3D APOBEC3B NEDD4 APOBEC3F

5.85e-05340265GO:0019058
GeneOntologyBiologicalProcessRNA modification

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

6.61e-05176264GO:0009451
GeneOntologyBiologicalProcessregulation protein catabolic process at postsynapse

NEDD4L NEDD4

6.83e-0510262GO:0140252
GeneOntologyBiologicalProcessregulation of viral process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

8.19e-05186264GO:0050792
GeneOntologyBiologicalProcessheparin biosynthetic process

NDST4 NDST1

8.35e-0511262GO:0030210
GeneOntologyBiologicalProcessregulation protein catabolic process at synapse

NEDD4L NEDD4

1.38e-0414262GO:0140250
GeneOntologyBiologicalProcesspositive regulation of gene expression via chromosomal CpG island demethylation

APOBEC3C APOBEC3F

1.59e-0415262GO:0044029
GeneOntologyBiologicalProcesssmall molecule catabolic process

APOBEC3C APOBEC3D MIOX APOBEC3B APOBEC3F

1.60e-04421265GO:0044282
GeneOntologyBiologicalProcessnegative regulation of sodium ion transmembrane transporter activity

NEDD4L NEDD4

1.81e-0416262GO:2000650
GeneOntologyBiologicalProcessregulation of defense response to virus

APOBEC3D APOBEC3B APOBEC3F

1.94e-0490263GO:0050688
GeneOntologyBiologicalProcessnegative regulation of sodium ion transmembrane transport

NEDD4L NEDD4

2.05e-0417262GO:1902306
GeneOntologyBiologicalProcessheparin metabolic process

NDST4 NDST1

2.05e-0417262GO:0030202
GeneOntologyBiologicalProcessviral process

APOBEC3C APOBEC3D APOBEC3B NEDD4 APOBEC3F

2.51e-04464265GO:0016032
GeneOntologyBiologicalProcessnegative regulation of sodium ion transport

NEDD4L NEDD4

3.48e-0422262GO:0010766
GeneOntologyBiologicalProcesscarbohydrate derivative catabolic process

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

6.72e-04323264GO:1901136
GeneOntologyBiologicalProcessdefense response to virus

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

8.32e-04342264GO:0051607
GeneOntologyBiologicalProcessheparan sulfate proteoglycan biosynthetic process

NDST4 NDST1

8.86e-0435262GO:0015012
GeneOntologyBiologicalProcessregulation of postsynaptic neurotransmitter receptor internalization

NEDD4L NEDD4

1.10e-0339262GO:0099149
GeneOntologyBiologicalProcessnucleobase-containing compound catabolic process

APOBEC3C APOBEC3D UPF1 APOBEC3B APOBEC3F

1.57e-03696265GO:0034655
GeneOntologyBiologicalProcessresponse to virus

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.85e-03425264GO:0009615
GeneOntologyBiologicalProcesspostsynaptic endocytosis

NEDD4L NEDD4

1.88e-0351262GO:0140239
GeneOntologyBiologicalProcesspostsynaptic neurotransmitter receptor internalization

NEDD4L NEDD4

1.88e-0351262GO:0098884
GeneOntologyBiologicalProcesshematopoietic progenitor cell differentiation

APOBEC3D APOBEC3B APOBEC3F

1.90e-03197263GO:0002244
GeneOntologyBiologicalProcessprotein monoubiquitination

NEDD4L NEDD4

2.10e-0354262GO:0006513
GeneOntologyBiologicalProcesssodium ion transmembrane transport

NEDD4L SLC6A17 NEDD4

2.21e-03208263GO:0035725
GeneOntologyBiologicalProcessregulation of sodium ion transmembrane transporter activity

NEDD4L NEDD4

2.34e-0357262GO:2000649
GeneOntologyBiologicalProcessneurotransmitter receptor internalization

NEDD4L NEDD4

2.42e-0358262GO:0099590
GeneOntologyBiologicalProcessprotein deacylation

NDST1 ABHD13

2.42e-0358262GO:0035601
GeneOntologyBiologicalProcessmacromolecule deacylation

NDST1 ABHD13

2.85e-0363262GO:0098732
GeneOntologyBiologicalProcessregulation of potassium ion transmembrane transporter activity

NEDD4L NEDD4

2.85e-0363262GO:1901016
GeneOntologyBiologicalProcessDNA-templated transcription initiation

UBTFL6 APOBEC3C APOBEC3F

2.98e-03231263GO:0006352
GeneOntologyBiologicalProcesstranscription initiation-coupled chromatin remodeling

APOBEC3C APOBEC3F

3.03e-0365262GO:0045815
GeneOntologyBiologicalProcesspositive regulation of gene expression, epigenetic

APOBEC3C APOBEC3F

3.31e-0368262GO:0141137
GeneOntologyBiologicalProcessregulation of sodium ion transmembrane transport

NEDD4L NEDD4

3.40e-0369262GO:1902305
GeneOntologyBiologicalProcessproteoglycan biosynthetic process

NDST4 NDST1

3.50e-0370262GO:0030166
GeneOntologyBiologicalProcesscarbohydrate derivative metabolic process

NDST4 NDST1 APOBEC3C APOBEC3D APOBEC3B APOBEC3F

3.59e-031226266GO:1901135
GeneOntologyBiologicalProcesspolysaccharide biosynthetic process

NDST4 NDST1

4.11e-0376262GO:0000271
GeneOntologyBiologicalProcessglycosaminoglycan biosynthetic process

NDST4 NDST1

4.11e-0376262GO:0006024
GeneOntologyBiologicalProcessaminoglycan biosynthetic process

NDST4 NDST1

4.55e-0380262GO:0006023
GeneOntologyBiologicalProcesssodium ion transport

NEDD4L SLC6A17 NEDD4

4.86e-03275263GO:0006814
GeneOntologyBiologicalProcessnegative regulation of ion transmembrane transporter activity

NEDD4L NEDD4

5.35e-0387262GO:0032413
GeneOntologyCellularComponentP-body

APOBEC3C APOBEC3D UPF1 APOBEC3B APOBEC3F

1.86e-07102275GO:0000932
GeneOntologyCellularComponentcytoplasmic ribonucleoprotein granule

APOBEC3C APOBEC3D UPF1 APOBEC3B APOBEC3F

2.18e-05269275GO:0036464
GeneOntologyCellularComponentribonucleoprotein granule

APOBEC3C APOBEC3D UPF1 APOBEC3B APOBEC3F

2.97e-05287275GO:0035770
MousePhenodecreased susceptibility to Ortervirales infection

APOBEC3D APOBEC3B APOBEC3F

3.92e-0712183MP:0020920
MousePhenoincreased susceptibility to Retroviridae infection

APOBEC3D APOBEC3B APOBEC3F

3.92e-0712183MP:0020934
MousePhenodecreased susceptibility to Retroviridae infection

APOBEC3D APOBEC3B APOBEC3F

3.92e-0712183MP:0020935
MousePhenoincreased susceptibility to Ortervirales infection

APOBEC3D APOBEC3B APOBEC3F

5.09e-0713183MP:0020919
MousePhenoabnormal susceptibility to Retroviridae infection

APOBEC3D APOBEC3B APOBEC3F

1.71e-0619183MP:0020933
MousePhenoabnormal susceptibility to Ortervirales infection

APOBEC3D APOBEC3B APOBEC3F

2.02e-0620183MP:0020918
MousePhenoabnormal immunoglobulin level

APOBEC3D APOBEC3B RASGRP3 NEDD4 APOBEC3F

3.76e-04513185MP:0002490
MousePhenoabnormal tumor morphology

APOBEC3D APOBEC3B APOBEC3F

4.81e-04122183MP:0003448
MousePhenodecreased susceptibility to viral infection

APOBEC3D APOBEC3B APOBEC3F

5.16e-04125183MP:0002410
MousePhenoabnormal humoral immune response

APOBEC3D APOBEC3B RASGRP3 NEDD4 APOBEC3F

5.81e-04564185MP:0001800
DomainAPOBEC_N

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.45e-0912264IPR013158
DomainAPOBEC_N

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.45e-0912264PF08210
DomainAPOBEC/CMP_deaminase_Zn-bd

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

2.92e-0914264IPR016192
DomainCMP_dCMP_Zn-bd

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

6.93e-0917264IPR002125
DomainCYT_DCMP_DEAMINASES_1

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

6.93e-0917264PS00903
DomainCytidine_deaminase-like

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

6.93e-0917264IPR016193
DomainCYT_DCMP_DEAMINASES_2

APOBEC3C APOBEC3B APOBEC3F

1.08e-0615263PS51747
DomainTAAR1

TAAR9 TAAR1

1.86e-062262IPR009133
DomainHSNSD

NDST4 NDST1

1.12e-054262PF12062
DomainHeparan_SO4_deacetylase

NDST4 NDST1

1.12e-054262IPR021930
DomainTAAR_fam

TAAR9 TAAR1

3.90e-057262IPR009132
DomainHECT

NEDD4L NEDD4

6.40e-0427262PF00632
DomainHECTc

NEDD4L NEDD4

6.40e-0427262SM00119
DomainHECT_dom

NEDD4L NEDD4

6.40e-0427262IPR000569
DomainHECT

NEDD4L NEDD4

6.40e-0427262PS50237
DomainAbhydrolase_1

ABHD13 EPHX4

8.45e-0431262PF00561
DomainAB_hydrolase_1

ABHD13 EPHX4

9.58e-0433262IPR000073
DomainSulfotransferase_dom

NDST4 NDST1

1.14e-0336262IPR000863
DomainSulfotransfer_1

NDST4 NDST1

1.14e-0336262PF00685
DomainWW

NEDD4L NEDD4

1.94e-0347262PF00397
DomainWW

NEDD4L NEDD4

2.02e-0348262SM00456
DomainWW_DOMAIN_2

NEDD4L NEDD4

2.28e-0351262PS50020
DomainWW_DOMAIN_1

NEDD4L NEDD4

2.28e-0351262PS01159
DomainWW_dom

NEDD4L NEDD4

2.37e-0352262IPR001202
Domain7TM_GPCR_Srsx

TAAR9 TAAR1

1.05e-02112262SM01381
Domain-

ABHD13 EPHX4

1.18e-021192623.40.50.1820
DomainAB_hydrolase

ABHD13 EPHX4

1.18e-02119262IPR029058
DomainGPCR_Rhodpsn_7TM

OR4D1 TAAR9 TAAR1 GPR18

1.31e-02670264IPR017452
Domain7tm_1

OR4D1 TAAR9 TAAR1 GPR18

1.36e-02677264PF00001
DomainG_PROTEIN_RECEP_F1_1

OR4D1 TAAR9 TAAR1 GPR18

1.41e-02685264PS00237
DomainC2

NEDD4L NEDD4

1.42e-02131262PF00168
DomainG_PROTEIN_RECEP_F1_2

OR4D1 TAAR9 TAAR1 GPR18

1.45e-02691264PS50262
DomainGPCR_Rhodpsn

OR4D1 TAAR9 TAAR1 GPR18

1.46e-02692264IPR000276
DomainC2

NEDD4L NEDD4

1.55e-02137262SM00239
DomainC2

NEDD4L NEDD4

1.66e-02142262PS50004
Domain-

NEDD4L NEDD4

1.79e-021482622.60.40.150
DomainC2_dom

NEDD4L NEDD4

2.17e-02164262IPR000008
PathwayREACTOME_MRNA_EDITING_C_TO_U_CONVERSION

APOBEC3D APOBEC3B APOBEC3F

9.93e-087213MM15412
PathwayREACTOME_MRNA_EDITING

APOBEC3D APOBEC3B APOBEC3F

2.38e-079213MM15445
PathwayREACTOME_MRNA_EDITING_C_TO_U_CONVERSION

APOBEC3C APOBEC3B

5.89e-058212M27683
PathwayREACTOME_MRNA_EDITING

APOBEC3C APOBEC3B

9.44e-0510212M27709
PathwayKEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_BIOSYNTHESIS

NDST4 NDST1

1.15e-0411212M47921
PathwayKEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE

NDST4 NDST1

6.72e-0426212M7330
PathwayREACTOME_HS_GAG_BIOSYNTHESIS

NDST4 NDST1

8.38e-0429212MM14802
PathwayREACTOME_HS_GAG_BIOSYNTHESIS

NDST4 NDST1

9.58e-0431212M685
PathwayWP_GLYCOSAMINOGLYCAN_SYNTHESIS_IN_FIBROBLASTS

NDST4 NDST1

1.67e-0341212M48095
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

TAAR9 TAAR1

1.76e-0342212MM14971
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

TAAR9 TAAR1

1.76e-0342212M5868
PathwayREACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM

NDST4 NDST1

2.89e-0354212MM14633
PathwayREACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM

NDST4 NDST1

3.21e-0357212M692
Pubmed

Species-specific restriction of apobec3-mediated hypermutation.

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

2.88e-13427418032489
Pubmed

Restriction by APOBEC3 proteins of endogenous retroviruses with an extracellular life cycle: ex vivo effects and in vivo "traces" on the murine IAPE and human HERV-K elements.

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

2.88e-13427418702815
Pubmed

HIV-1 Vif, APOBEC, and intrinsic immunity.

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.44e-12527418577210
Pubmed

The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements.

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.44e-12527418304004
Pubmed

Retroelements versus APOBEC3 family members: No great escape from the magnificent seven.

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

4.31e-12627422912627
Pubmed

An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22.

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.01e-11727411863358
Pubmed

APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons.

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.01e-11727416527742
Pubmed

Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1.

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.01e-11727421835787
Pubmed

APOBEC3 proteins mediate the clearance of foreign DNA from human cells.

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

1.01e-11727420062055
Pubmed

APOBEC3 deaminases induce hypermutation in human papillomavirus 16 DNA upon beta interferon stimulation.

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

2.01e-11827424227842
Pubmed

Introduction to thematic minireview series: Understanding human immunodeficiency virus-host interactions at the biochemical level.

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

6.03e-111027423043103
Pubmed

Leveraging APOBEC3 proteins to alter the HIV mutation rate and combat AIDS.

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

6.03e-111027420174454
Pubmed

Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business.

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

9.47e-111127412683974
Pubmed

HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies.

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

9.47e-111127422915799
Pubmed

Murine Leukemia Virus P50 Protein Counteracts APOBEC3 by Blocking Its Packaging.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327332641479
Pubmed

APOBEC3 signature mutations in chronic lymphocytic leukemia.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327324840555
Pubmed

Role of APOBEC3 in genetic diversity among endogenous murine leukemia viruses.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327317967065
Pubmed

APOBEC3 deletion increases the risk of breast cancer: a meta-analysis.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327327602762
Pubmed

The APOBEC3C crystal structure and the interface for HIV-1 Vif binding.

APOBEC3C APOBEC3D APOBEC3F

4.17e-10327323001005
Pubmed

Inhibition of xenotropic murine leukemia virus-related virus by APOBEC3 proteins and antiviral drugs.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327320335265
Pubmed

Anti-Friend virus antibody is associated with recovery from viremia and loss of viral leukemia cell-surface antigens in leukemic mice. Identification of Rfv-3 as a gene locus influencing antibody production.

APOBEC3D APOBEC3B APOBEC3F

4.17e-103273286744
Pubmed

Deaminase-Dead Mouse APOBEC3 Is an In Vivo Retroviral Restriction Factor.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327329593034
Pubmed

A novel role for APOBEC3: susceptibility to sexual transmission of murine acquired immunodeficiency virus (mAIDS) is aggravated in APOBEC3 deficient mice.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327322691411
Pubmed

Mouse APOBEC3 interferes with autocatalytic cleavage of murine leukemia virus Pr180gag-pol precursor and inhibits Pr65gag processing.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327331830125
Pubmed

Studies on the restriction of murine leukemia viruses by mouse APOBEC3.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327322666481
Pubmed

Requirement for CD4(+) T cells in the Friend murine retrovirus neutralizing antibody response: evidence for functional T cells in genetic low-recovery mice.

APOBEC3D APOBEC3B APOBEC3F

4.17e-1032739765497
Pubmed

APOBEC3 deletion polymorphism is associated with epithelial ovarian cancer risk among Chinese women.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327324577894
Pubmed

Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327321998583
Pubmed

Biochemical and biological studies of mouse APOBEC3.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327324453360
Pubmed

Host restriction of murine gammaherpesvirus 68 replication by human APOBEC3 cytidine deaminases but not murine APOBEC3.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327324725948
Pubmed

APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327316648136
Pubmed

Direct inhibition of human APOBEC3 deaminases by HIV-1 Vif independent of the proteolysis pathway.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327338115583
Pubmed

Fv1 restriction and retrovirus vaccine immunity in Apobec3-deficient 129P2 mice.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327323533681
Pubmed

The glycosylated Gag protein of a murine leukemia virus inhibits the antiretroviral function of APOBEC3.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327320702647
Pubmed

Spontaneous recovery from Friend retrovirus-induced leukemia. Mapping of the Rfv-2 gene in the Q/TL region of mouse MHC.

APOBEC3D APOBEC3B APOBEC3F

4.17e-1032731541833
Pubmed

In Vivo Examination of Mouse APOBEC3- and Human APOBEC3A- and APOBEC3G-Mediated Restriction of Parvovirus and Herpesvirus Infection in Mouse Models.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327327356895
Pubmed

APOBEC3 inhibition of mouse mammary tumor virus infection: the role of cytidine deamination versus inhibition of reverse transcription.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327323449789
Pubmed

IFN-α treatment inhibits acute Friend retrovirus replication primarily through the antiviral effector molecule Apobec3.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327323315078
Pubmed

Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327320980520
Pubmed

Requirement for Fc effector mechanisms in the APOBEC3/Rfv3-dependent neutralizing antibody response.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327325589647
Pubmed

Identification of a non-H-2 gene (Rfv-3) influencing recovery from viremia and leukemia induced by Friend virus complex.

APOBEC3D APOBEC3B APOBEC3F

4.17e-103273284359
Pubmed

Effects of zidovudine on Friend virus complex infection in Rfv-3r/s genotype-containing mice used as a model for HIV infection.

APOBEC3D APOBEC3B APOBEC3F

4.17e-1032732157836
Pubmed

Adaptive evolution of Mus Apobec3 includes retroviral insertion and positive selection at two clusters of residues flanking the substrate groove.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327320617165
Pubmed

Distinctive High Expression of Antiretroviral APOBEC3 Protein in Mouse Germinal Center B Cells.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327335458563
Pubmed

Impact of Suboptimal APOBEC3G Neutralization on the Emergence of HIV Drug Resistance in Humanized Mice.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327331801862
Pubmed

Two genetic determinants acquired late in Mus evolution regulate the inclusion of exon 5, which alters mouse APOBEC3 translation efficiency.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327322275865
Pubmed

APOBEC3-independent interferon-induced viral clearance in hepatitis B virus transgenic mice.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327318434399
Pubmed

Identification of specific determinants of human APOBEC3F, APOBEC3C, and APOBEC3DE and African green monkey APOBEC3F that interact with HIV-1 Vif.

APOBEC3C APOBEC3D APOBEC3F

4.17e-10327320943965
Pubmed

Apobec-mediated retroviral hypermutation in vivo is dependent on mouse strain.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327339208378
Pubmed

Deamination hotspots among APOBEC3 family members are defined by both target site sequence context and ssDNA secondary structure.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327331943071
Pubmed

Induction of APOBEC3 in vivo causes increased restriction of retrovirus infection.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327319153238
Pubmed

Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327318772436
Pubmed

Antibody-induced modulation of Friend virus cell surface antigens decreases virus production by persistent erythroleukemia cells: influence of the Rfv-3 gene.

APOBEC3D APOBEC3B APOBEC3F

4.17e-103273293683
Pubmed

Enhanced replication and pathogenesis of Moloney murine leukemia virus in mice defective in the murine APOBEC3 gene.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327319150103
Pubmed

Murine leukemia virus glycosylated Gag blocks apolipoprotein B editing complex 3 and cytosolic sensor access to the reverse transcription complex.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327323671100
Pubmed

Structural perspectives on HIV-1 Vif and APOBEC3 restriction factor interactions.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327331518043
Pubmed

Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327320566830
Pubmed

Chromosome mapping of Rfv3, a host resistance gene to Friend murine retrovirus.

APOBEC3D APOBEC3B APOBEC3F

4.17e-1032737884913
Pubmed

N-linked glycosylation protects gammaretroviruses against deamination by APOBEC3 proteins.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327325505062
Pubmed

Molecular analysis of γ1, γ3, and α class switch recombination junctions in APOBEC3-deficient mice using high-throughput sequencing.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327331595054
Pubmed

Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327318786991
Pubmed

Initial sequencing and comparative analysis of the mouse genome.

APOBEC3D APOBEC3B APOBEC3F

4.17e-10327312466850
Pubmed

Immunoglobulin somatic hypermutation by APOBEC3/Rfv3 during retroviral infection.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427324821801
Pubmed

Small molecular compounds inhibit HIV-1 replication through specifically stabilizing APOBEC3G.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427320363737
Pubmed

The incorporation of APOBEC3 proteins into murine leukemia viruses.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427318572219
Pubmed

Murine APOBEC1 is a powerful mutator of retroviral and cellular RNA in vitro and in vivo.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427318983852
Pubmed

The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427338049664
Pubmed

Expression and subcellular localisation of AID and APOBEC3 in adenoid and palatine tonsils.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427329343743
Pubmed

APOBEC3 regulates keratinocyte differentiation and expression of Notch3.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427331400166
Pubmed

APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427315674295
Pubmed

Virus-specific CD8+ T cells upregulate programmed death-1 expression during acute friend retrovirus infection but are highly cytotoxic and control virus replication.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427321873525
Pubmed

Ribonuclease L is not critical for innate restriction and adaptive immunity against Friend retrovirus infection.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427323725696
Pubmed

Restriction of foamy viruses by APOBEC cytidine deaminases.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427316378963
Pubmed

Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427326846717
Pubmed

Vaccinia virus replication is not affected by APOBEC3 family members.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427317052331
Pubmed

APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427321985787
Pubmed

Distinct determinants in HIV-1 Vif and human APOBEC3 proteins are required for the suppression of diverse host anti-viral proteins.

APOBEC3C APOBEC3D APOBEC3F

1.67e-09427319088851
Pubmed

APOBEC3A functions as a restriction factor of human papillomavirus.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427325355878
Pubmed

Type I interferon signaling is required for the APOBEC3/Rfv3-dependent neutralizing antibody response but not innate retrovirus restriction.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427328415995
Pubmed

Human and murine APOBEC3s restrict replication of koala retrovirus by different mechanisms.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427326253512
Pubmed

Immunity to retroviral infection: the Friend virus model.

APOBEC3D APOBEC3B APOBEC3F

1.67e-0942739223268
Pubmed

A patch of positively charged amino acids surrounding the human immunodeficiency virus type 1 Vif SLVx4Yx9Y motif influences its interaction with APOBEC3G.

APOBEC3C APOBEC3D APOBEC3F

1.67e-09427319535450
Pubmed

APOBEC3 enzymes restrict marginal zone B cells.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427325501566
Pubmed

HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427320538015
Pubmed

Reversed functional organization of mouse and human APOBEC3 cytidine deaminase domains.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427317020885
Pubmed

Persistence of viremia and production of neutralizing antibodies differentially regulated by polymorphic APOBEC3 and BAFF-R loci in friend virus-infected mice.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427320375169
Pubmed

APOBEC3 proteins expressed in mammary epithelial cells are packaged into retroviruses and can restrict transmission of milk-borne virions.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427321147467
Pubmed

Multifaceted HIV-1 Vif interactions with human E3 ubiquitin ligase and APOBEC3s.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427332893454
Pubmed

Reassessment of murine APOBEC1 as a retrovirus restriction factor in vivo.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427325303118
Pubmed

APOBEC3 inhibits mouse mammary tumour virus replication in vivo.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427317259974
Pubmed

HIV restriction by APOBEC3 in humanized mice.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427323555255
Pubmed

The Cytidine Deaminase APOBEC3G Contributes to Cancer Mutagenesis and Clonal Evolution in Bladder Cancer.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427336480186
Pubmed

Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427315269786
Pubmed

Mice deficient in APOBEC2 and APOBEC3.

APOBEC3D APOBEC3B APOBEC3F

1.67e-09427316055735
Pubmed

Host restriction of HIV-1 by APOBEC3 and viral evasion through Vif.

APOBEC3C APOBEC3D APOBEC3F

4.17e-09527320012521
Pubmed

APOBEC3 inhibits DEAD-END function to regulate microRNA activity.

APOBEC3D APOBEC3B APOBEC3F

4.17e-09527323890083
Pubmed

A computational analysis of the structural determinants of APOBEC3's catalytic activity and vulnerability to HIV-1 Vif.

APOBEC3C APOBEC3D APOBEC3F

4.17e-09527325461536
Pubmed

Phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein.

APOBEC3D APOBEC3B APOBEC3F

4.17e-09527321659520
Pubmed

IFN-α and lipopolysaccharide upregulate APOBEC3 mRNA through different signaling pathways.

APOBEC3D APOBEC3B APOBEC3F

4.17e-09527322972924
Pubmed

AID and APOBECs span the gap between innate and adaptive immunity.

APOBEC3C APOBEC3D APOBEC3F

4.17e-09527325352838
InteractionAPOBEC3D interactions

APOBEC3C APOBEC3D UPF1 APOBEC3B APOBEC3F

1.41e-06148275int:APOBEC3D
InteractionPRRG3 interactions

NEDD4L NEDD4

1.72e-055272int:PRRG3
InteractionPABPC5 interactions

APOBEC3D UPF1 APOBEC3B APOBEC3F

3.66e-05142274int:PABPC5
InteractionCYYR1 interactions

NEDD4L NEDD4

4.82e-058272int:CYYR1
InteractionNDST4 interactions

NDST4 NDST1

4.82e-058272int:NDST4
InteractionCGAS interactions

APOBEC3C APOBEC3D UPF1 NEDD4 APOBEC3F

6.76e-05329275int:CGAS
InteractionMS4A10 interactions

NEDD4L NEDD4

7.73e-0510272int:MS4A10
InteractionPRRG2 interactions

NEDD4L NEDD4

7.73e-0510272int:PRRG2
InteractionTMEM252 interactions

NEDD4L NEDD4

9.44e-0511272int:TMEM252
InteractionILDR1 interactions

NEDD4L NEDD4

9.44e-0511272int:ILDR1
InteractionSCN10A interactions

NEDD4L NEDD4

9.44e-0511272int:SCN10A
InteractionLAPTM5 interactions

NEDD4L REEP5 NEDD4

9.70e-0567273int:LAPTM5
InteractionELAVL2 interactions

APOBEC3D UPF1 APOBEC3B APOBEC3F

1.09e-04188274int:ELAVL2
InteractionLITAF interactions

NEDD4L REEP5 NEDD4

1.47e-0477273int:LITAF
InteractionMOB3A interactions

NEDD4L NEDD4

1.56e-0414272int:MOB3A
InteractionPRRG1 interactions

NEDD4L NEDD4

1.80e-0415272int:PRRG1
InteractionPRR16 interactions

NEDD4L NEDD4

2.05e-0416272int:PRR16
InteractionSCN3A interactions

NEDD4L NEDD4

2.05e-0416272int:SCN3A
InteractionSUSD6 interactions

NEDD4L NEDD4

2.05e-0416272int:SUSD6
InteractionABT1 interactions

APOBEC3C APOBEC3D UPF1 APOBEC3B APOBEC3F

2.19e-04423275int:ABT1
InteractionZC3H3 interactions

APOBEC3C APOBEC3D UPF1 APOBEC3F

2.21e-04226274int:ZC3H3
InteractionTMEM255A interactions

NEDD4L NEDD4

2.32e-0417272int:TMEM255A
InteractionTMEM92 interactions

NEDD4L NEDD4

2.32e-0417272int:TMEM92
InteractionTAF1B interactions

APOBEC3C NEDD4L NEDD4

2.49e-0492273int:TAF1B
InteractionTMEM174 interactions

NEDD4L NEDD4

2.61e-0418272int:TMEM174
InteractionLARP4B interactions

APOBEC3D UPF1 APOBEC3B APOBEC3F

2.78e-04240274int:LARP4B
InteractionRASL11B interactions

NEDD4L NEDD4

2.91e-0419272int:RASL11B
InteractionSCN2A interactions

NEDD4L NEDD4

2.91e-0419272int:SCN2A
InteractionPRR3 interactions

APOBEC3C UPF1 APOBEC3B APOBEC3F

3.05e-04246274int:PRR3
InteractionCLIC2 interactions

NEDD4L NEDD4

3.24e-0420272int:CLIC2
InteractionSCN8A interactions

NEDD4L NEDD4

3.24e-0420272int:SCN8A
InteractionRBMS2 interactions

APOBEC3D UPF1 APOBEC3B APOBEC3F

3.29e-04251274int:RBMS2
InteractionKCNQ1 interactions

NEDD4L NEDD4

3.57e-0421272int:KCNQ1
InteractionSCN9A interactions

NEDD4L NEDD4

3.57e-0421272int:SCN9A
InteractionGSPT2 interactions

UPF1 APOBEC3B APOBEC3F

3.88e-04107273int:GSPT2
InteractionSLC22A8 interactions

NEDD4L NEDD4

3.93e-0422272int:SLC22A8
InteractionSCNN1G interactions

NEDD4L NEDD4

3.93e-0422272int:SCNN1G
InteractionKCNAB1 interactions

NEDD4L NEDD4

5.09e-0425272int:KCNAB1
InteractionSLC22A6 interactions

NEDD4L NEDD4

6.39e-0428272int:SLC22A6
InteractionSCNN1B interactions

NEDD4L NEDD4

6.39e-0428272int:SCNN1B
InteractionFBXL15 interactions

NEDD4L NEDD4

6.86e-0429272int:FBXL15
InteractionSCN1A interactions

NEDD4L NEDD4

6.86e-0429272int:SCN1A
InteractionPYM1 interactions

UPF1 NEDD4L NEDD4

7.32e-04133273int:PYM1
InteractionRNFT1 interactions

ABHD13 REEP5

8.36e-0432272int:RNFT1
InteractionNDST1 interactions

NDST4 NDST1

9.44e-0434272int:NDST1
InteractionNUP42 interactions

UPF1 REEP5 APOBEC3F

1.02e-03149273int:NUP42
InteractionRNF7 interactions

NEDD4L NEDD4 APOBEC3F

1.04e-03150273int:RNF7
InteractionPIP4P2 interactions

NEDD4L NEDD4

1.12e-0337272int:PIP4P2
InteractionN4BP1 interactions

NEDD4L NEDD4

1.18e-0338272int:N4BP1
CytobandEnsembl 112 genes in cytogenetic band chr22q13

APOBEC3C APOBEC3D MIOX APOBEC3B APOBEC3F

1.32e-06330275chr22q13
Cytoband22q13.1

APOBEC3C APOBEC3D APOBEC3F

1.73e-058527322q13.1
Cytoband6q23.2

TAAR9 TAAR1

9.91e-05252726q23.2
CytobandEnsembl 112 genes in cytogenetic band chr17q22

OR4D1 TEX14

1.24e-0388272chr17q22
CytobandEnsembl 112 genes in cytogenetic band chr6q23

TAAR9 TAAR1

2.24e-03119272chr6q23
GeneFamilyApolipoprotein B mRNA editing enzyme catalytic subunits

APOBEC3C APOBEC3D APOBEC3B APOBEC3F

8.08e-1012224406
GeneFamilyTrace amine receptors

TAAR9 TAAR1

5.06e-059222188
GeneFamilyAbhydrolase domain containing

ABHD13 EPHX4

3.22e-04222224
GeneFamilySulfotransferases, membrane bound

NDST4 NDST1

9.17e-0437222763
GeneFamilyT-cell receptor alpha locus at 14q11.2

TRAV38-2DV8 TRA

8.81e-03117222371
CoexpressionTABULA_MURIS_SENIS_LUNG_CD4_POSITIVE_ALPHA_BETA_T_CELL_AGEING

APOBEC3D REEP5 APOBEC3B APOBEC3F

9.56e-06142254MM3757
CoexpressionTABULA_MURIS_SENIS_THYMUS_DN4_THYMOCYTE_AGEING

APOBEC3D GPR18 APOBEC3B APOBEC3F

7.22e-05238254MM3845
CoexpressionMARTIN_VIRAL_GPCR_SIGNALING_UP

STEAP4 TAAR9 GPR18

7.44e-0586253M1327
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

APOBEC3C APOBEC3D GPR18 APOBEC3F

5.12e-0619127495ae42d145adb478d886a2259baacc713cd6587b
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 NEDD4L KIF13A NEDD4

5.33e-06193274a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NEDD4L KIF13A RASGRP3 NEDD4

5.33e-06193274aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NEDD4L KIF13A RASGRP3 NEDD4

5.33e-06193274c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellSigmoid-T_cell-cycling_gd_T|T_cell / Region, Cell class and subclass

STEAP4 APOBEC3D TEX14 RASGRP3

6.14e-062002744e489ecf472857357d45e9f6c7a812aa48b72ebf
ToppCell390C-Lymphocytic-Plasma_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

MIOX APOBEC3B RASGRP3

1.13e-041562730de2fc695bd5f8d4633c514f71ea941c88137bac
ToppCellIIH-CD8-memory_CD4|IIH / Condition, Cell_class and T cell subcluster

OR4D1 EPHX4 TRAV38-2DV8

1.13e-04156273e312fc4317d966fb2b570d1a4a3aa865f781ea93
ToppCell390C-Lymphocytic-Plasma_cell-|390C / Donor, Lineage, Cell class and subclass (all cells)

MIOX APOBEC3B RASGRP3

1.13e-041562734f92ca30755430db44402afc603d1ecd8bfc3617
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEX14 REEP5 SLC6A17

1.19e-041592737619d0d49738dd08daf01b42664691a5323aa793
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TEX14 REEP5 SLC6A17

1.19e-041592734000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

OR4D1 NDST1 NEDD4

1.33e-04165273436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

OR4D1 NDST1 NEDD4

1.33e-04165273242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCellBronchial_Brush-Immune-B_cells|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

GPR18 APOBEC3B RASGRP3

1.43e-04169273dc388f660f69e37e517bf3243daf071ab138ee6e
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EPHX4 APOBEC3B NEDD4

1.45e-04170273330b5fc8fde307eda9dcc7bc9053ea8a7e1f0f6d
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EPHX4 APOBEC3B NEDD4

1.45e-041702730c9d38e89b048166b879e6b4bdf7c5dfe8ab57c4
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STEAP4 NEDD4L APOBEC3B

1.48e-04171273d5960b40ad5b87aaa00c93a6b31cdf41cc4f1375
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STEAP4 NEDD4L APOBEC3B

1.48e-04171273fd59ac4a39748840b2ee1c930ea475433ff61485
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STEAP4 NEDD4L APOBEC3B

1.48e-04171273d382430e5cdd0f2aac4fc093d8fe8d66efb4629b
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STEAP4 NEDD4L APOBEC3B

1.48e-041712734347e6f62c04ea43299893ad4b79719049009a56
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NDST1 NEDD4L APOBEC3B

1.69e-04179273d5e3e7f1cd8f683f39a7416f12af7e766dcbead8
ToppCell5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHX4 SLC6A17 RASGRP3

1.72e-04180273af7c4b9f1a0ddd894085cf93c29a6d253a7d077c
ToppCell5'-GW_trimst-1-SmallIntestine-Endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHX4 SLC6A17 RASGRP3

1.72e-04180273e35e9159f5cd9ec905b3b6e27d938158aeb9c51c
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

STEAP4 TEX14 NEDD4L

1.72e-04180273b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 STEAP4 SLC6A17

1.72e-0418027378fdcfb3fdbf36469cae78407cda5bd0996930d8
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

THSD4 NEDD4L NEDD4

1.74e-04181273c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF13A RASGRP3 NEDD4

1.80e-04183273e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 STEAP4 SLC6A17

1.83e-04184273f4344f3c407b2d4d703fe56e43d84dbfe60ba833
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

THSD4 STEAP4 NEDD4L

1.86e-04185273cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF13A RASGRP3 NEDD4

1.92e-04187273ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

THSD4 STEAP4 NEDD4L

1.95e-04188273707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

THSD4 NEDD4L RASGRP3

2.04e-041912735d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellNS-critical-d_07-13-Lymphoid-CTL|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

APOBEC3C APOBEC3D GPR18

2.08e-04192273e7e5ba94ee8fd3c04bb4c358c86d0227c563e9dc
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 STEAP4 SLC6A17

2.11e-041932731043b28503bfaa0d5a82ec358bc86cbde73ea8f2
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 STEAP4 SLC6A17

2.11e-041932730266a4fdf436d83ec1d9392abba8c6ec5166970a
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NEDD4L RASGRP3 NEDD4

2.11e-04193273e1d546165dcc2392f540162206852c4717d7306f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 RASGRP3 NEDD4

2.14e-04194273ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

THSD4 NEDD4L RASGRP3

2.14e-04194273c3535f7cc0076653c72db582047cff053c322397
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasmablast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MIOX RASGRP3 APOBEC3F

2.17e-04195273c6e31038be2463f1601d52c82efa4e9facb8228f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 RASGRP3 NEDD4

2.20e-0419627348b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 RASGRP3 NEDD4

2.20e-04196273473980c827443464d08a0be28c53e3536369b12a
ToppCellBL-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

APOBEC3C APOBEC3D GPR18

2.20e-04196273cfbeaabbeeb197f0cf8240a752d1f2995d59d7b7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 RASGRP3 NEDD4

2.20e-041962738f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 NEDD4L NEDD4

2.24e-041972735bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 NEDD4L KIF13A

2.27e-041982731996373bdccc55aac347d349bd22f6aad6d0c668
DrugC0761

APOBEC3C APOBEC3B APOBEC3F

6.52e-088253CID006321196
DrugN-cyclopropylammelide

APOBEC3C APOBEC3B APOBEC3F

6.52e-088253CID000592814
DiseaseLiddle syndrome (implicated_via_orthology)

NEDD4L NEDD4

4.13e-064252DOID:0050477 (implicated_via_orthology)
Diseaseazoospermia (implicated_via_orthology)

NDST4 NDST1

2.39e-0427252DOID:14227 (implicated_via_orthology)
Diseaseintellectual disability (implicated_via_orthology)

NDST4 NDST1

1.84e-0375252DOID:1059 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

NDST4 NDST1

7.32e-03152252DOID:0060041 (implicated_via_orthology)
Diseaseautism spectrum disorder

THSD4 NEDD4L

7.69e-03156252EFO_0003756

Protein segments in the cluster

PeptideGeneStartEntry
SFFPMRYLPLWCYKN

ABHD13

231

Q7L211
EGQPFMPWYKFDDNY

APOBEC3D

176

Q96AK3
QQFMPWYKFDENYAF

APOBEC3B

166

Q9UH17
PFRMFYYAKDEWPFG

GPR18

76

Q14330
AMYPGTFYFQFKNLW

APOBEC3C

11

Q9NRW3
WFFLISKEMFNPYYG

NEDD4

1011

P46934
YYYFFQIPWFPEFMF

EPHX4

216

Q8IUS5
YHKGIDWYMEFFPIP

NDST1

651

P52848
YHKGIDWYMDFFPTP

NDST4

641

Q9H3R1
FDFQWPQPDKPMFFY

UPF1

746

Q92900
YSEGQPFMPWYKFDD

APOBEC3F

161

Q8IUX4
PFMPWYKFDDNYAFL

APOBEC3F

166

Q8IUX4
YIYTWPFTPFLMDKA

OR4D1

256

Q15615
PEAFYMIRFHSFYPW

MIOX

211

Q9UGB7
PPKVFAFDYCFWSMD

KIF13A

51

Q9H1H9
YSFGFGKAMPWFQFY

TEX14

206

Q8IWB6
MNPLIYAFFYQWFGK

TAAR9

306

Q96RI9
YFMRYWILKFPAEFN

RASGRP3

76

Q8IV61
FLSWFPFYYMLKCGF

REEP5

106

Q00765
FYLFYNFEYWFLPMK

CLN5

321

O75503
NFEYWFLPMKFPFIK

CLN5

326

O75503
RFFKENWPQYSQMYP

UBTFL6

116

P0CB48
DYYLFWYKQPPSRQM

TRA

51

P0DTU3
KYPLQLFPMWRFPFY

STEAP4

191

Q687X5
NSTFNPMVYAFFYPW

TAAR1

296

Q96RJ0
PMVYAFFYPWFRKAL

TAAR1

301

Q96RJ0
DYYLFWYKQPPSRQM

TRAV38-2DV8

51

A0JD32
FYFFKSFQYPLPWSE

SLC6A17

166

Q9H1V8
YNNKPFMGRFYEWEP

THSD4

321

Q6ZMP0
EWFFLLSKEMFNPYY

NEDD4L

666

Q96PU5