Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glucuronosyltransferase activity	UGT2A1 UGT2A2 B3GAT2 LARGE1	9.28e-06	35	76	4	GO:0015020
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GABRB1 GABRG2 CHRNA1 CHRNA3	6.57e-05	57	76	4	GO:1904315
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	GABRB1 GABRG2 CHRNA1 CHRNA3	8.04e-05	60	76	4	GO:0099529
GeneOntologyMolecularFunction	transmitter-gated channel activity	GABRB1 GABRG2 CHRNA1 CHRNA3	1.10e-04	65	76	4	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	GABRB1 GABRG2 CHRNA1 CHRNA3	1.10e-04	65	76	4	GO:0022824
GeneOntologyMolecularFunction	postsynaptic neurotransmitter receptor activity	GABRB1 GABRG2 CHRNA1 CHRNA3	1.92e-04	75	76	4	GO:0098960
GeneOntologyMolecularFunction	extracellular ligand-gated monoatomic ion channel activity	GABRB1 GABRG2 CHRNA1 CHRNA3	2.12e-04	77	76	4	GO:0005230
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	GABRB1 GABRG2 SLC4A7 ANO5 ANKH	4.91e-04	171	76	5	GO:0015103
GeneOntologyMolecularFunction	neurotransmitter receptor activity	GABRB1 GABRG2 CHRNA1 CHRNA3	5.76e-04	100	76	4	GO:0030594
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	GABRB1 GABRG2 ANO5 CHRNA1 CHRNA3	8.49e-04	193	76	5	GO:0015276
GeneOntologyMolecularFunction	ligand-gated monoatomic anion channel activity	GABRB1 GABRG2 ANO5	9.13e-04	50	76	3	GO:0099095
GeneOntologyMolecularFunction	ligand-gated channel activity	GABRB1 GABRG2 ANO5 CHRNA1 CHRNA3	9.31e-04	197	76	5	GO:0022834
GeneOntologyMolecularFunction	transporter activity	GABRB1 GABRG2 ATP6V1A SLC4A7 LRP2 ANO5 ATP13A3 SLC22A24 SLC10A7 TMEM87A ANKH CHRNA1 CHRNA3	1.07e-03	1289	76	13	GO:0005215
GeneOntologyMolecularFunction	acetylcholine binding	CHRNA1 CHRNA3	1.09e-03	13	76	2	GO:0042166
GeneOntologyMolecularFunction	transmembrane transporter activity	GABRB1 GABRG2 ATP6V1A SLC4A7 ANO5 ATP13A3 SLC22A24 SLC10A7 TMEM87A ANKH CHRNA1 CHRNA3	1.59e-03	1180	76	12	GO:0022857
GeneOntologyMolecularFunction	gated channel activity	GABRB1 GABRG2 ANO5 TMEM87A CHRNA1 CHRNA3	1.71e-03	334	76	6	GO:0022836
GeneOntologyMolecularFunction	monoatomic ion channel activity	GABRB1 GABRG2 ATP6V1A ANO5 TMEM87A CHRNA1 CHRNA3	1.81e-03	459	76	7	GO:0005216
GeneOntologyMolecularFunction	acetylcholine-gated monoatomic cation-selective channel activity	CHRNA1 CHRNA3	1.87e-03	17	76	2	GO:0022848
GeneOntologyMolecularFunction	GABA-gated chloride ion channel activity	GABRB1 GABRG2	2.10e-03	18	76	2	GO:0022851
GeneOntologyMolecularFunction	GABA-A receptor activity	GABRB1 GABRG2	2.34e-03	19	76	2	GO:0004890
GeneOntologyMolecularFunction	GABA receptor binding	GABRB1 GABARAPL2	2.60e-03	20	76	2	GO:0050811
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	GABRB1 GABRG2 SLC4A7 ANO5	2.64e-03	151	76	4	GO:0008509
GeneOntologyMolecularFunction	UDP-glycosyltransferase activity	UGT2A1 UGT2A2 B3GAT2 LARGE1	2.77e-03	153	76	4	GO:0008194
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	GABRB1 GABRG2 ATP6V1A SLC4A7 ANO5 ATP13A3 TMEM87A CHRNA1 CHRNA3	3.10e-03	793	76	9	GO:0015075
GeneOntologyMolecularFunction	GABA receptor activity	GABRB1 GABRG2	3.14e-03	22	76	2	GO:0016917
GeneOntologyMolecularFunction	acetylcholine receptor activity	CHRNA1 CHRNA3	3.43e-03	23	76	2	GO:0015464
GeneOntologyMolecularFunction	channel activity	GABRB1 GABRG2 ATP6V1A ANO5 TMEM87A CHRNA1 CHRNA3	3.82e-03	525	76	7	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	GABRB1 GABRG2 ATP6V1A ANO5 TMEM87A CHRNA1 CHRNA3	3.86e-03	526	76	7	GO:0022803
GeneOntologyMolecularFunction	chloride channel activity	GABRB1 GABRG2 ANO5	4.32e-03	86	76	3	GO:0005254
Domain	Neurotransmitter_ion_chnl_CS	GABRB1 GABRG2 CHRNA1 CHRNA3	2.83e-05	45	73	4	IPR018000
Domain	Neur_chan_memb	GABRB1 GABRG2 CHRNA1 CHRNA3	3.10e-05	46	73	4	PF02932
Domain	Neur_chan_LBD	GABRB1 GABRG2 CHRNA1 CHRNA3	3.37e-05	47	73	4	PF02931
Domain	NEUROTR_ION_CHANNEL	GABRB1 GABRG2 CHRNA1 CHRNA3	3.37e-05	47	73	4	PS00236
Domain	Neurotrans-gated_channel_TM	GABRB1 GABRG2 CHRNA1 CHRNA3	3.37e-05	47	73	4	IPR006029
Domain	-	GABRB1 GABRG2 CHRNA1 CHRNA3	3.37e-05	47	73	4	2.70.170.10
Domain	Neur_channel	GABRB1 GABRG2 CHRNA1 CHRNA3	3.37e-05	47	73	4	IPR006201
Domain	Neur_chan_lig-bd	GABRB1 GABRG2 CHRNA1 CHRNA3	3.37e-05	47	73	4	IPR006202
Domain	Nicotinic_acetylcholine_rcpt	CHRNA1 CHRNA3	1.75e-03	16	73	2	IPR002394
Domain	-	CHRNA1 CHRNA3	3.61e-03	23	73	2	1.20.120.370
Domain	GABAA/Glycine_rcpt	GABRB1 GABRG2	3.61e-03	23	73	2	IPR006028
Domain	Acetylcholine_rcpt_TM	CHRNA1 CHRNA3	3.61e-03	23	73	2	IPR027361
Pubmed	Capturing host-pathogen interactions by protein microarrays: identification of novel streptococcal proteins binding to human fibronectin, fibrinogen, and C4BP.	FN1 C4BPA	4.97e-06	2	78	2	19417080
Pubmed	The UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste.	UGT2A1 UGT2A2	4.97e-06	2	78	2	35039640
Pubmed	Rat olfactory bulb and epithelium UDP-glucuronosyltransferase 2A1 (UGT2A1) expression: in situ mRNA localization and quantitative analysis.	UGT2A1 UGT2A2	4.97e-06	2	78	2	11376859
Pubmed	Cloning and characterization of a novel human olfactory UDP-glucuronosyltransferase.	UGT2A1 UGT2A2	4.97e-06	2	78	2	10359671
Pubmed	Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.	KPNA4 EPS15L1 TC2N STON2 GABARAPL2	5.07e-06	110	78	5	37219487
Pubmed	Smokers with the CHRNA lung cancer-associated variants are exposed to higher levels of nicotine equivalents and a carcinogenic tobacco-specific nitrosamine.	CHRNA1 CHRNA3	1.49e-05	3	78	2	19010884
Pubmed	Quantitative proteomics revealed novel proteins associated with molecular subtypes of breast cancer.	FN1 C4BPA	1.49e-05	3	78	2	27498393
Pubmed	USP44 Stabilizes DDB2 to Facilitate Nucleotide Excision Repair and Prevent Tumors.	USP44 XPC	1.49e-05	3	78	2	33937266
Pubmed	The Human UDP-glucuronosyltransferase UGT2A1 and UGT2A2 enzymes are highly active in bile acid glucuronidation.	UGT2A1 UGT2A2	1.49e-05	3	78	2	23756265
Pubmed	Histamine action on vertebrate GABAA receptors: direct channel gating and potentiation of GABA responses.	GABRB1 GABRG2	1.49e-05	3	78	2	18281286
Pubmed	Mapping of the glycoprotein 330 (Gp330) gene to mouse chromosome 2.	LRP2 CHRNA1	1.49e-05	3	78	2	8244399
Pubmed	Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3.	UGT2A1 UGT2A2	1.49e-05	3	78	2	19858781
Pubmed	Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology.	GABRB1 GABRG2	1.49e-05	3	78	2	2538761
Pubmed	Serum amyloid p component does not circulate in complex with C4-binding protein, fibronectin or any other major protein ligand.	FN1 C4BPA	2.97e-05	4	78	2	12100475
Pubmed	Evaluating the effect of nicotinic cholinergic receptor genes on the risk of nonsyndromic cleft lip with or without cleft palate.	CHRNA1 CHRNA3	2.97e-05	4	78	2	29688589
Pubmed	Validation study of genetic associations with coronary artery disease on chromosome 3q13-21 and potential effect modification by smoking.	MYLK ARHGAP31	2.97e-05	4	78	2	19706030
Pubmed	Structure of the Eps15-stonin2 complex provides a molecular explanation for EH-domain ligand specificity.	EPS15L1 STON2	2.97e-05	4	78	2	18200045
Pubmed	Mutational analysis of FANCL, FANCM and the recently identified FANCI suggests that among the 13 known Fanconi Anemia genes, only FANCD1/BRCA2 plays a major role in high-risk breast cancer predisposition.	BRCA2 FANCM	2.97e-05	4	78	2	19737859
Pubmed	Longitudinal profiling identifies co-occurring BRCA1/2 reversions, TP53BP1, RIF1 and PAXIP1 mutations in PARP inhibitor-resistant advanced breast cancer.	RIF1 BRCA2	4.94e-05	5	78	2	38244928
Pubmed	Identification of the cAMP-dependent protein kinase and protein kinase C phosphorylation sites within the major intracellular domains of the beta 1, gamma 2S, and gamma 2L subunits of the gamma-aminobutyric acid type A receptor.	GABRB1 GABRG2	4.94e-05	5	78	2	1321150
Pubmed	The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence.	PKHD1 LRP2	4.94e-05	5	78	2	20048263
Pubmed	Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily.	UGT2A1 UGT2A2	4.94e-05	5	78	2	16141793
Pubmed	Expression and functional analysis of a cytoplasmic domain variant of the beta 1 integrin subunit.	FN1 ITGA1	4.94e-05	5	78	2	7681433
Pubmed	The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse.	GABRG2 GABARAPL2	4.94e-05	5	78	2	10900017
Pubmed	New insight into the central benzodiazepine receptor-ligand interactions: design, synthesis, biological evaluation, and molecular modeling of 3-substituted 6-phenyl-4H-imidazo[1,5-a][1,4]benzodiazepines and related compounds.	GABRB1 GABRG2	7.40e-05	6	78	2	21751815
Pubmed	Interactions between ultraviolet light exposure and DNA repair gene polymorphisms may increase melanoma risk.	BRCA2 XPC	7.40e-05	6	78	2	20199546
Pubmed	Arf4 is required for Mammalian development but dispensable for ciliary assembly.	PKHD1 LRP2	1.04e-04	7	78	2	24586199
Pubmed	theta, a novel gamma-aminobutyric acid type A receptor subunit.	GABRB1 GABRG2	1.04e-04	7	78	2	10449790
Pubmed	Stonin 2: an adaptor-like protein that interacts with components of the endocytic machinery.	EPS15L1 STON2	1.38e-04	8	78	2	11381094
Pubmed	Genetic variation in DNA repair genes and prostate cancer risk: results from a population-based study.	BRCA2 XPC	1.77e-04	9	78	2	19902366
Pubmed	Sources of energy for gating by neurotransmitters in acetylcholine receptor channels.	CHRNA1 CHRNA3	1.77e-04	9	78	2	22647603
Pubmed	Precise temporal regulation of alternative splicing during neural development.	GABRG2 MBNL1	1.77e-04	9	78	2	29875359
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	KPNA4 SLC4A7 MAN2B1 ERCC6L SCD AKAP10	2.11e-04	378	78	6	34315543
Pubmed	Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair.	RIF1 FANCM	2.21e-04	10	78	2	23509288
Pubmed	Integrin repertoire on myogenic cells changes during the course of primary myogenesis in the mouse.	FN1 ITGA1	2.70e-04	11	78	2	15739233
Pubmed	Immunolocalization of extracellular matrix components and integrins during mouse liver development.	FN1 ITGA1	2.70e-04	11	78	2	15368439
Pubmed	A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland.	LRP2 CHRNA1	3.23e-04	12	78	2	8631881
Pubmed	Mapping of three members of the mouse protein disulfide isomerase family.	LRP2 CHRNA1	3.23e-04	12	78	2	9457688
Pubmed	A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.	FN1 MBNL1 ANO5	3.39e-04	60	78	3	19075228
Pubmed	The biochemical anatomy of cortical inhibitory synapses.	GABRB1 GABRG2	4.44e-04	14	78	2	22768092
Pubmed	USP44 Is an Integral Component of N-CoR that Contributes to Gene Repression by Deubiquitinating Histone H2B.	USP44 XPC	4.44e-04	14	78	2	27880911
Pubmed	Design and expression of human alpha7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties.	CHRNA1 CHRNA3	4.44e-04	14	78	2	19059502
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	GABRB1 CNTN5 STON2 FHDC1 SPAG17 CHRNA3 B3GAT2 NLRP8	4.82e-04	814	78	8	23251661
Pubmed	Analysis of nicotinic acetylcholine receptor subunits in the cochlea of the mouse.	CHRNA1 CHRNA3	5.12e-04	15	78	2	8838678
Pubmed	Head bobber: an insertional mutation causes inner ear defects, hyperactive circling, and deafness.	FN1 CPXM2	5.12e-04	15	78	2	22383091
Pubmed	Muscleblind-like 1 is required for normal heart valve development in vivo.	FN1 MBNL1	5.12e-04	15	78	2	26472242
Pubmed	Patterning and folding of intestinal villi by active mesenchymal dewetting.	MYLK FN1	5.12e-04	15	78	2	38781967
Pubmed	Integrins in the mouse myotome: developmental changes and differences between the epaxial and hypaxial lineage.	FN1 ITGA1	5.12e-04	15	78	2	15366018
Pubmed	Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.	GABRG2 RIF1 OTC SLC4A7	5.30e-04	165	78	4	16107646
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	RIF1 THSD7A LRP2	5.56e-04	71	78	3	33541421
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	TRAPPC11 PTPN9 ERCC6L MUC16 ADAM30 MRPL41 XPC	5.80e-04	638	78	7	31182584
Pubmed	Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.	CHRNA1 CHRNA3	5.84e-04	16	78	2	19259974
Pubmed	Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.	BRCA2 FANCM	5.84e-04	16	78	2	27760317
Pubmed	Human variation in alcohol response is influenced by variation in neuronal signaling genes.	XPC CHRNA1 CHRNA3 LARGE1	6.06e-04	171	78	4	20201926
Pubmed	Large-scale genotyping identifies 41 new loci associated with breast cancer risk.	SLC4A7 BRCA2 CDYL2	6.78e-04	76	78	3	23535729
Pubmed	Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.	GABRB1 GABRG2	7.42e-04	18	78	2	19078961
Pubmed	Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis.	FN1 ITGA1	7.42e-04	18	78	2	19686679
Pubmed	GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality.	GABRB1 GABRG2	7.42e-04	18	78	2	18985723
Pubmed	Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis.	ATP6V1A LRP2	8.28e-04	19	78	2	16177003
Pubmed	No evidence for association between 19 cholinergic genes and bipolar disorder.	CHRNA1 CHRNA3	8.28e-04	19	78	2	17373692
Pubmed	ETAA1 acts at stalled replication forks to maintain genome integrity.	BRCA2 FANCM	1.01e-03	21	78	2	27723720
Pubmed	Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.	PKHD1 LRP2	1.01e-03	21	78	2	27591083
Pubmed	Smooth muscle contraction and relaxation.	MYLK ITGA1	1.11e-03	22	78	2	14627618
Pubmed	Transforming growth factor-β signaling in myogenic cells regulates vascular morphogenesis, differentiation, and matrix synthesis.	MYLK FN1	1.11e-03	22	78	2	21979435
Pubmed	Fanconi Anemia	BRCA2 FANCM	1.22e-03	23	78	2	20301575
Pubmed	Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence.	FN1 ITGA1	1.22e-03	23	78	2	23152823
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	KPNA4 ATP6V1A PTPN9 ERCC6L XPC DYNC1LI2	1.27e-03	533	78	6	25544563
Pubmed	Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas.	GABRB1 GABRG2	1.33e-03	24	78	2	22534482
Pubmed	Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.	GABRG2 FN1 CHRNA3	1.42e-03	98	78	3	19834535
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	GON4L FANCM ANKH	1.54e-03	101	78	3	10997877
Pubmed	Comprehensive analysis of DNA repair gene polymorphisms and survival in patients with early stage non-small-cell lung cancer.	BRCA2 XPC	1.56e-03	26	78	2	20731661
Pubmed	Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia.	SCD LRP2	1.68e-03	27	78	2	28167773
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	SLC4A7 ERCC6L ARHGAP31 STON2 ATP13A3 TMEM87A	1.77e-03	569	78	6	30639242
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RANBP17 ATP6V1A EPS15L1 SPTSSA SH3TC1 MBNL1 CDYL2 KYAT3 SLC10A7 ANKH	1.79e-03	1489	78	10	28611215
Pubmed	Genetic variation in immune regulation and DNA repair pathways and stomach cancer in China.	BRCA2 XPC	1.81e-03	28	78	2	19661089
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ATP6V1A RIF1 EPS15L1 SLC4A7 FN1 MUC16 DYNC1LI2	1.81e-03	777	78	7	35844135
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	SLC4A7 PIK3CB LRP2 LARGE1	1.90e-03	233	78	4	32290105
Pubmed	Genome-wide association study of smoking behaviours in patients with COPD.	CPXM2 GIMAP2	1.94e-03	29	78	2	21685187
Pubmed	Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function.	MYLK SCD	2.07e-03	30	78	2	27133129
Pubmed	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	ITGA1 CHRNA3	2.07e-03	30	78	2	21946350
Pubmed	Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation.	SCD GABARAPL2	2.07e-03	30	78	2	31693883
Pubmed	Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk.	BRCA2 FANCM	2.21e-03	31	78	2	19690177
Cytoband	1p12	ADAM30 SPAG17	8.12e-04	25	77	2	1p12
Cytoband	2q34	KANSL1L FN1	1.02e-03	28	77	2	2q34
Cytoband	Ensembl 112 genes in cytogenetic band chr15q24	LMAN1L PTPN9 STOML1	1.16e-03	122	77	3	chr15q24
Cytoband	5q34	RANBP17 GABRG2	1.33e-03	32	77	2	5q34
Cytoband	10q26.13	CPXM2 MMP21	1.88e-03	38	77	2	10q26.13
GeneFamily	Cholinergic receptors nicotinic subunits	CHRNA1 CHRNA3	9.85e-04	16	53	2	173
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRB1 GABRG2	1.40e-03	19	53	2	563
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	BRCA2 FANCM	1.55e-03	20	53	2	548
ToppCell	343B-Epithelial_cells-Epithelial-A_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	SPTSSA SCD LRP2 C4BPA FHDC1 TMEM87A	3.79e-07	164	76	6	beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCell	343B-Epithelial_cells-Epithelial-A_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	SPTSSA SCD LRP2 C4BPA FHDC1 TMEM87A	3.79e-07	164	76	6	d005cfd821b87548b075120bffe65a0be9860463
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	MYLK FN1 CPXM2 MBNL1 UNC13C ITGA1	8.43e-07	188	76	6	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	MYLK FN1 CPXM2 MBNL1 UNC13C ITGA1	8.69e-07	189	76	6	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP44 SPTSSA SCD C4BPA FHDC1 TMEM87A	9.24e-07	191	76	6	6cb2c107bc674aa173b4009f320a1687a76f3979
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP44 SPTSSA SCD LRP2 C4BPA FHDC1	1.04e-06	195	76	6	d9694db6bf239636d1335016878c98f6ee2eb0eb
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPTSSA MYLK SCD LRP2 C4BPA FHDC1	1.07e-06	196	76	6	82b117be41f2e7d677a42d2a5198726eeccb16d0
ToppCell	(7)_Epithelial-B_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	USP44 SPTSSA SCD LRP2 C4BPA TMEM87A	1.07e-06	196	76	6	345d4cc062b43bca9d506fbf23363469a9ba496f
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	USP44 SPTSSA SCD LRP2 C4BPA TMEM87A	1.11e-06	197	76	6	f3ca63c7902d7530a29a85eb54f69b303031d150
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	USP44 SPTSSA SCD LRP2 C4BPA TMEM87A	1.11e-06	197	76	6	f98720cab066579fdac3ba24fb6fe4c5759dae4e
ToppCell	BAL-Mild-cDC_4\|Mild / Compartment, Disease Groups and Clusters	WDR91 CDYL2 MUC16 FANCM SLC10A7	1.39e-05	179	76	5	68511e87b12b8253de7771e5ccfc5869248b8450
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 LRP2 ANO5 UNC13C SPAG17	1.58e-05	184	76	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	THSD7A CPXM2 CNTN5 UNC13C CHRNA3	1.58e-05	184	76	5	658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 LRP2 ANO5 UNC13C SPAG17	1.58e-05	184	76	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 LRP2 ANO5 UNC13C SPAG17	1.58e-05	184	76	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	STON2 PKHD1 LRP2 ANO5 C4BPA	1.58e-05	184	76	5	fa4915b0498f3069fd5ef497286445528f75187e
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GABRG2 CNTN5 PKHD1 MUC16 SPAG17	1.67e-05	186	76	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SH3TC1 CDYL2 DNAAF9 FANCM ANKH	1.67e-05	186	76	5	bca5215d406f1785bf3a420201d5686071fcaca5
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	USP44 RANBP17 PKHD1 C4BPA TMEM87A	1.71e-05	187	76	5	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	SH3TC1 XPC ITGA1 FANCM B3GAT2	1.71e-05	187	76	5	816d37a70f7ec382a268fe828b3dfe737a36a4bf
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP31 SCD STON2 LRP2 RFTN2	1.80e-05	189	76	5	42ab4cc5fbf8580841f31889446fe4499df1a464
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPTSSA MYLK FN1 SCD C4BPA	1.89e-05	191	76	5	f00d6824bd138b192a996e9f7de57b235bb24c18
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	USP44 TC2N CPXM2 PKHD1 LRP2	1.99e-05	193	76	5	b38aaffbea36ef6c08ebe82675438f873c89b242
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPTSSA MYLK SCD C4BPA FHDC1	1.99e-05	193	76	5	ba484fa1f290a92ae02475a4c468b4ac840c133e
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPTSSA SCD LRP2 C4BPA FHDC1	2.09e-05	195	76	5	6617abca0009ad3d8731f515f91ab275f9ea4c40
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SPTSSA SCD C4BPA FHDC1 TMEM87A	2.09e-05	195	76	5	6867f9c56ea27a17c8c4099aae0d79903c3748a5
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPTSSA SCD LRP2 C4BPA FHDC1	2.09e-05	195	76	5	fc0ae145a2118df7cbbc9ac4ca9dc12d26c087c4
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SPTSSA SCD C4BPA FHDC1 TMEM87A	2.09e-05	195	76	5	955a0a7244cd7eaf006a39e1bd03333baf6f30a4
ToppCell	ASK440-Epithelial-Type_2\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	USP44 SCD C4BPA FHDC1 TMEM87A	2.14e-05	196	76	5	754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP44 SPTSSA SCD C4BPA FHDC1	2.14e-05	196	76	5	9d267dd293fde05f04febc0a9d15776c5b782a1c
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPTSSA SCD C4BPA FHDC1 TMEM87A	2.14e-05	196	76	5	65e161fd672e37a5d10f28011bb422c4d7042d6a
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPTSSA SCD LRP2 C4BPA FHDC1	2.14e-05	196	76	5	006d783a530aa6e1e6545dcc2e6b00bb300fe070
ToppCell	ASK440-Epithelial-Type_2\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	USP44 SCD C4BPA FHDC1 TMEM87A	2.20e-05	197	76	5	08d5bbeb77a4152af1c783bc958afcae24667767
ToppCell	medial-2-Epithelial-Alveolar_Epithelial_Type_2\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SPTSSA TC2N LRP2 C4BPA FHDC1	2.25e-05	198	76	5	102a4cbb138adbfba11ed955420095daa098532f
ToppCell	medial-Epithelial-Alveolar_Epithelial_Type_2-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SPTSSA TC2N LRP2 C4BPA FHDC1	2.25e-05	198	76	5	7caeed2d5dc78866023c8f38edcec9886baa9f2c
ToppCell	medial-Epithelial-Alveolar_Epithelial_Type_2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SPTSSA TC2N LRP2 C4BPA FHDC1	2.25e-05	198	76	5	53e5d76831d70b9a476f3ef3a81e13eda974d543
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-B_(AT2)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	SPTSSA SCD LRP2 C4BPA TMEM87A	2.25e-05	198	76	5	391f59e232269f6ae9f8792d21a60ad534e03c4d
ToppCell	Biopsy_Other_PF-Epithelial-AT2\|Biopsy_Other_PF / Sample group, Lineage and Cell type	TC2N SCD LRP2 C4BPA FHDC1	2.30e-05	199	76	5	9a65acfe9bf500db72142469cf17bf0973540001
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SPTSSA SCD LRP2 C4BPA TMEM87A	2.30e-05	199	76	5	df157604a7e2b6e7fa2d21660ca749a3552b945c
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SCD LRP2 C4BPA FHDC1 TMEM87A	2.30e-05	199	76	5	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SPTSSA SCD LRP2 C4BPA TMEM87A	2.30e-05	199	76	5	48626e54ce94b5ea3001fc5d447509a50c073aa4
ToppCell	Parenchyma_COVID-19-Epithelial-TX-AT2-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	USP44 SPTSSA SCD LRP2 C4BPA	2.36e-05	200	76	5	cf1991853e10c562edae9a0d71a209f35b07db80
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	USP44 SPTSSA SCD LRP2 C4BPA	2.36e-05	200	76	5	7618ae284625c5c121bcc00eb9f07e5b1e3adf23
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	USP44 SPTSSA SCD LRP2 C4BPA	2.36e-05	200	76	5	23b319bf7e5ae03e5baa777c951da9bfc97cca8c
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_3\|367C / Donor, Lineage, Cell class and subclass (all cells)	THSD7A SCD SSH3 CHRNA3	7.49e-05	131	76	4	aeeb5718b3a7122492ad2659d5c8112f60839ff3
ToppCell	Mild/Remission-B_intermediate-14\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SSH3 STON2 CDYL2 ANO5	8.17e-05	134	76	4	5bd1e3fa6278facd9e949e9e5e244e700190126b
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CDYL2 MUC16 FANCM SLC10A7	1.23e-04	149	76	4	a85a051e0d82430160967e72fa04b55f43e84513
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CDYL2 MUC16 FANCM SLC10A7	1.26e-04	150	76	4	7a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCell	TCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	UGT2A1 PKHD1 LRP2 SLC22A24	1.40e-04	154	76	4	89a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCell	TCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	UGT2A1 PKHD1 LRP2 SLC22A24	1.40e-04	154	76	4	f1fea1a87e977221fa125b62287368be9af4987d
ToppCell	TCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	UGT2A1 PKHD1 LRP2 SLC22A24	1.40e-04	154	76	4	b5604c0b0b9b283352a3f612f40883b9123475d1
ToppCell	TCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal-1\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	UGT2A1 PKHD1 LRP2 SLC22A24	1.40e-04	154	76	4	160b170a3ade8b246843c9854af332475c047ba0
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BRCA2 SCD LRP2 FHDC1	1.86e-04	166	76	4	575c325db88d6909cdf0d5e664bd9098b89d4401
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KANSL1L OR9A4 PKHD1 SPAG17	2.04e-04	170	76	4	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	droplet-Lung-nan-21m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP44 MAN2B1 ANKH CHRNA1	2.04e-04	170	76	4	d72eb77271d61e27a3d247149561c7f45fadb28b
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD7A SH3TC1 FHDC1 TMEM87A	2.18e-04	173	76	4	4968712af1cca8c932abd3323631d7dcaffd4a66
ToppCell	facs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RANBP17 MYLK CPXM2 UNC13C	2.23e-04	174	76	4	197686570cec6d96a92e77e6409325d3bfe6f991
ToppCell	facs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RANBP17 MYLK CPXM2 UNC13C	2.23e-04	174	76	4	2eee7b5471672b439f95eba11494c2adf8cb7006
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)\|390C / Donor, Lineage, Cell class and subclass (all cells)	SPTSSA SCD LRP2 C4BPA	2.49e-04	179	76	4	466da2bc3bfc534ffe111c8c28ece7a3cfa08051
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	SPTSSA SCD LRP2 C4BPA	2.49e-04	179	76	4	f4bdebb77d39e63160fbf3a85a340ce4d52b7cfd
ToppCell	droplet-Liver-LIVER-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LMAN1L THSD7A CPXM2 UNC13C	2.54e-04	180	76	4	3d95232b5785c705f41e01e3ffe0fa8dce1ff0a7
ToppCell	droplet-Liver-LIVER-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LMAN1L THSD7A CPXM2 UNC13C	2.54e-04	180	76	4	47e345359064dc8ceec982b062e47802e728b43f
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	MYLK FN1 CPXM2 ITGA1	2.54e-04	180	76	4	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	droplet-Lung-LUNG-30m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TC2N SCD LRP2 FHDC1	2.59e-04	181	76	4	cadb18fc73031eb9f779599e15cd7861337fee78
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYLK FN1 UNC13C ITGA1	2.59e-04	181	76	4	d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell	droplet-Lung-LUNG-30m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TC2N SCD LRP2 FHDC1	2.59e-04	181	76	4	85bec4d3f255f4c61c790325eeb50ad38f709ef2
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-5\|TCGA-Breast / Sample_Type by Project: Shred V9	FN1 ERCC6L SCD CHRNA1	2.65e-04	182	76	4	9e48d5b634603bc7a8d29290202a311457678328
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	MYLK FN1 CPXM2 ITGA1	2.70e-04	183	76	4	818fd886e0188091310825f9145fa53328f2c979
ToppCell	facs-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A MMP21 ATP13A3 FHDC1	2.70e-04	183	76	4	12e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	MYLK FN1 CPXM2 ITGA1	2.70e-04	183	76	4	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	KANSL1L PKHD1 LRP2 SLC22A24	2.76e-04	184	76	4	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	RANBP17 SCD LRP2 C4BPA	2.76e-04	184	76	4	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	IPF-Epithelial-ATII\|IPF / Disease state, Lineage and Cell class	RANBP17 LRP2 C4BPA FHDC1	2.82e-04	185	76	4	563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYLK CPXM2 ADAM30 SPAG17	2.82e-04	185	76	4	30df02fbe2828e3c4f3e5c4cda855e74fb31be39
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	OTC THSD7A FN1 ATP13A3	2.82e-04	185	76	4	b57dae20c21f984edd2acee4344d86f033108ebf
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	OTC THSD7A FN1 ATP13A3	2.82e-04	185	76	4	d3b054d203e575c1bb5455aa7a2e551a0957a760
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TC2N MYLK CNTN5 UNC13C	2.82e-04	185	76	4	5a0340c25196453f19e424d346efbf66d2c53ac3
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SH3TC1 ITGA1 FANCM B3GAT2	2.88e-04	186	76	4	74c238759c5d3fd39127ec0060d0c2cb16b326d4
ToppCell	IPF-Epithelial-ATII\|World / Disease state, Lineage and Cell class	RANBP17 LRP2 C4BPA FHDC1	2.88e-04	186	76	4	6a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCell	facs-Lung-EPCAM-24m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCD PKHD1 LRP2 FHDC1	2.88e-04	186	76	4	3c4994a1a7db06a61da8170e45e06aaef7896592
ToppCell	facs-Lung-EPCAM-24m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCD PKHD1 LRP2 FHDC1	2.88e-04	186	76	4	a583d6fc0f1e729f6e9fd18d7b49d6eab9ca32b9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CNTN5 PKHD1 LRP2 SLC22A24	2.88e-04	186	76	4	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPTSSA SCD C4BPA FHDC1	2.94e-04	187	76	4	7c44cec1c26ca5907a495f2d7e633410e2e9728f
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	THSD7A MYLK FN1 ITGA1	2.94e-04	187	76	4	a9316e2818217ec5feae9cf8816f7249803caee6
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WDR91 SLC4A7 THSD7A PKHD1	2.94e-04	187	76	4	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KANSL1L STON2 PKHD1 LRP2	2.94e-04	187	76	4	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	SCD MBNL1 C4BPA FHDC1	2.94e-04	187	76	4	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYLK CPXM2 ADAM30 SPAG17	2.94e-04	187	76	4	8ff9f771d10c372d771c92dfa9006aa81aec4681
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	THSD7A CPXM2 SH3TC1 B3GAT2	3.00e-04	188	76	4	524d1d928c9386acf20e53d31894107dd7290dc7
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPTSSA ARHGAP31 AKAP10 LARGE1	3.00e-04	188	76	4	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPTSSA ARHGAP31 AKAP10 LARGE1	3.00e-04	188	76	4	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPTSSA ARHGAP31 AKAP10 LARGE1	3.00e-04	188	76	4	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	THSD7A CPXM2 SH3TC1 B3GAT2	3.00e-04	188	76	4	1b57995d70cf81212e8d46dfaf44dbaf9c7bc4d5
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	THSD7A CPXM2 SH3TC1 B3GAT2	3.00e-04	188	76	4	cd2d1f8e43c252dd8730a5758458ef63e7ffc836
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	THSD7A CPXM2 SH3TC1 B3GAT2	3.00e-04	188	76	4	f5a2f324f3f6c5078d57130392d3f1ba74f29094
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP31 SCD STON2 RFTN2	3.00e-04	188	76	4	505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TC2N CPXM2 PKHD1 LRP2	3.00e-04	188	76	4	beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCell	5'-Airway_Nasal-Endothelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	THSD7A CPXM2 SH3TC1 B3GAT2	3.00e-04	188	76	4	6c9d5e4014f807149328ff4eabd5e86dfe18094d
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SCD LRP2 C4BPA FHDC1	3.06e-04	189	76	4	da014519d6eb21bc2dc2ed65eafe638b42a068ed
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	THSD7A MYLK FN1 UNC13C	3.06e-04	189	76	4	203c80030df08ae112f9ae4043709f455d87ce89
Disease	Abnormality of the sense of smell, COVID-19 symptoms measurement, ageusia	UGT2A1 UGT2A2	6.04e-06	2	73	2	EFO_0600019, EFO_1001758, HP_0004408
Disease	alcohol use disorder (implicated_via_orthology)	PIK3CB SSH3 UNC13C CHRNA1 CHRNA3	1.25e-04	195	73	5	DOID:1574 (implicated_via_orthology)
Disease	major depressive episode	THSD7A CNTN5 SLC10A7	2.18e-04	47	73	3	EFO_0007634
Disease	Hepatic Encephalopathy	GABRB1 GABRG2	4.63e-04	13	73	2	C0019151
Disease	Hepatic Coma	GABRB1 GABRG2	4.63e-04	13	73	2	C0019147
Disease	Fulminant Hepatic Failure with Cerebral Edema	GABRB1 GABRG2	4.63e-04	13	73	2	C0751197
Disease	Hepatic Stupor	GABRB1 GABRG2	4.63e-04	13	73	2	C0751198
Disease	Autosomal recessive limb-girdle muscular dystrophy	TRAPPC11 ANO5	5.39e-04	14	73	2	cv:C2931907
Disease	Proteinuria	LRP2 UNC13C	6.21e-04	15	73	2	HP_0000093
Disease	hepatic encephalopathy (biomarker_via_orthology)	GABRB1 GABRG2	6.21e-04	15	73	2	DOID:13413 (biomarker_via_orthology)
Disease	Alcohol abuse	GABRG2 FN1 CHRNA3	6.21e-04	67	73	3	C0085762
Disease	congenital myasthenic syndrome (implicated_via_orthology)	CHRNA1 CHRNA3	7.08e-04	16	73	2	DOID:3635 (implicated_via_orthology)
Disease	forced expiratory volume, response to bronchodilator	KPNA4 MBNL1 SPAG17 CHRNA1 CHRNA3 LARGE1	8.26e-04	445	73	6	EFO_0004314, GO_0097366
Disease	Bone marrow hypocellularity	BRCA2 FANCM	9.00e-04	18	73	2	C1855710
Disease	physical activity	CNTN5 PKHD1 NLRP8	1.37e-03	88	73	3	EFO_0003940
Disease	Schizophrenia	GABRB1 GABRG2 PIK3CB MBNL1 STON2 LRP2 CHRNA3 B3GAT2	1.50e-03	883	73	8	C0036341
Disease	Fanconi Anemia	BRCA2 FANCM	1.75e-03	25	73	2	C0015625
Disease	Pancytopenia	BRCA2 FANCM	1.89e-03	26	73	2	C0030312
Disease	Limb-girdle muscular dystrophy	TRAPPC11 ANO5	1.89e-03	26	73	2	cv:C0686353
Disease	Miller Dieker syndrome	BRCA2 FANCM	2.35e-03	29	73	2	C0265219

Protein segments in the cluster

Peptide	Gene	Start	Entry
WMTPIFLKVVINTRR	PRO1854	31	Q9UHT4
WKVSDPILFQMTLIA	C4BPA	26	P04003
TVNWVVPVADKMRFD	EPS15L1	266	Q9UBC2
ISAWITKMEIPRTYQ	ANO5	536	Q75V66
WVKTVFLNLLPRVMF	CHRNA3	341	P32297
FTTPLRQAWTTMEKV	AKAP10	476	O43572
ILVVVFTMSLNPAWK	ATP13A3	976	Q9H7F0
WQTVKTVPEIITGDM	CNTN5	716	O94779
AETRAVIAWMEKIPF	CPXM2	496	Q8N436
TLWQRMVASVPFVKS	RANBP17	381	Q9H2T7
GIVQKPELEMFWSTR	PGBD4	166	Q96DM1
TKQIVFLQRPVMWNS	RFTN2	391	Q52LD8
WEQKVLVIVMTTRFE	PTPN9	391	P43378
HVMPNWVRKVFIDTI	CHRNA1	326	P02708
WVRKVFIDTIPNIMF	CHRNA1	331	P02708
RMRSFFWKTIPEEQV	FHDC1	96	Q9C0D6
LVSFRMNKDPWTVSI	MUC16	2191	Q8WXI7
SVLVPTIKSWMVSRQ	SLC10A7	316	Q0GE19
QYKEILTPSWRMVVL	KANSL1L	791	A0AUZ9
ILATLFQTWMVPAVR	LARGE1	181	O95461
PITCTWMKFRKQIQE	MYLK	1266	Q15746
LIMIRFTSWQTCKPL	NLRP8	331	Q86W28
VPFSAWEVEVQMRVT	LMAN1L	86	Q9HAT1
WCSKRVLFLTPQVMV	FANCM	181	Q8IYD8
TLVIFVADMSRPWTV	DYNC1LI2	131	O43237
RIVALAFRMWSEVTP	MMP21	196	Q8N119
SLVFPEAENRKWTIM	OTC	321	P00480
VNSIDKWSRMFFPIT	GABRB1	446	P18505
GSMRTVIVQDKIFWP	LRP2	1586	P98164
LFWSRDVAVVKVTMN	ITGA1	661	P56199
SFWPRVMEEIRNLTV	NFYC	21	Q13952
IFPKVATNIMRAWLF	MEIS3P2	251	A8K0S8
AIPSSIWVVSIIMFR	ADAM30	681	Q9UKF2
REIVIIDTPDMFSWK	GIMAP2	71	Q9UG22
IIQRAYPIQWMEKTS	BRCA2	2821	P51587
VEVTDVKVTIMWTPP	FN1	916	P02751
QEMRTTRKVSVWPVG	B3GAT2	196	Q9NPZ5
TPVFSQKMTVWILLL	GABRG2	16	P18507
PKQVAWILATSKVFM	GON4L	791	Q3T8J9
LQIFDMFVVEKWPIV	DNAAF9	171	Q5TEA3
MFVVEKWPIVQAFAL	DNAAF9	176	Q5TEA3
VMFWTPNVSEKILID	ANKH	341	Q9HCJ1
MAVSVTPIRDTKWLT	MBNL1	1	Q9NR56
KVNWMVRLPVSEGVF	MAN2B1	521	O00754
KIATFPGMWERTITI	KYAT3	261	Q6YP21
VPSDITVAQFMWIIR	GABARAPL2	51	P60520
IMPTNLINTWVKEFI	ERCC6L	151	Q2NKX8
IISFWNFKMRPKEIV	TAS2R20	246	P59543
SGWRFVQIKEMVPEF	MRPL41	46	Q8IXM3
LWVIKVSAAAVVFPM	SLC4A7	1096	Q9Y6M7
TEPWSICKVTFVNMR	THSD7A	1101	Q9UPZ6
RVKWGETMIFPLIQS	TC2N	416	Q8N9U0
STPIIVLFLSSWKMV	SLC22A24	266	Q8N4F4
FPVATMKTLLRTWSE	RIF1	696	Q5UIP0
QVRTVVMRPSVSWEK	SH3TC1	31	Q8TE82
TPKRWELMVSNTTFV	PKHD1	2461	P08F94
VPREATISYIKQMLW	PIK3CB	46	P42338
TQAKPVKNTFLRMWI	RWDD2A	146	Q9UIY3
NWVVSLMVSVVTPFL	OR9A4	271	Q8NGU2
PWERTVFNSMLVSIV	SPTSSA	31	Q969W0
VLRQDIMPTTTTKWI	STON2	626	Q8WXE9
AVQVPQRKLFSMVSW	SPAG17	56	Q6Q759
IFKPISIQTMWATLQ	SSH3	191	Q8TE77
VFWPTTFSQEVMLRV	CDYL2	431	Q8N8U2
WKRTSAMENIPIITT	TRAPPC11	986	Q7Z392
FWPQLITLMVTIIDE	UNC13C	1591	Q8NB66
QFRIWDPVLSVMTVK	STOML1	146	Q9UBI4
FVARMIPKVEWSAFL	TRMT112	41	Q9UI30
FQFLKMTTWILPKIT	ERVK-11	441	Q9UQG0
EKFTMVQVWPVRQVR	ATP6V1A	201	P38606
SPKVEYVWRNIILMS	SCD	66	O00767
TWVTPEGVTLRNKMT	ARHGAP31	1396	Q2M1Z3
TKIFQFLKMTTWILP	ERVK-19	441	Q9WJR5
VTQRYDPVWMTVTRK	XPC	581	Q01831
VIKVWSFNPIMQTKA	WDR91	431	A4D1P6
PSTIWRFYQEMAKVI	UGT2A1	101	P0DTE4
ILMGKIFRTWFEQSP	USP44	156	Q9H0E7
TTWLQEPMTFKDVAV	ZNF891	36	A8MT65
IVFIIWTTMKFRIVT	TMEM87A	416	Q8NBN3
VKPLDRAVFWIEFVM	UGT2A2	461	P0DTE5
SIPITFLRNVTWVMV	KPNA4	211	O00629