Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

4.71e-0651573GO:0030156
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor

ACADS ACADVL ACAD9

9.96e-05121573GO:0052890
GeneOntologyMolecularFunctionacyl-CoA dehydrogenase activity

ACADS ACADVL ACAD9

9.96e-05121573GO:0003995
GeneOntologyMolecularFunctiontransporter activity

CACNA1B SLC17A2 SLC25A27 AQP12A TTYH2 MFSD2B PKD1L2 SLC10A7 SLC1A4 AQP12B CHRNE SLC45A3 MLC1 UCP2 SLC35A2 HPX KCNMA1 ABCB11 CACNA1I TIMM29 RFT1 SLC25A28 SLC27A5

1.89e-04128915723GO:0005215
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DYNC1H1 DNAH11

3.57e-04181573GO:0008569
GeneOntologyMolecularFunctionlong-chain fatty acyl-CoA dehydrogenase activity

ACADVL ACAD9

3.65e-0441572GO:0004466
GeneOntologyMolecularFunctionToll-like receptor 2 binding

TLR6 TLR1

3.65e-0441572GO:0035663
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1B SLC17A2 SLC25A27 AQP12A TTYH2 MFSD2B PKD1L2 SLC10A7 SLC1A4 AQP12B CHRNE SLC45A3 MLC1 UCP2 SLC35A2 HPX KCNMA1 ABCB11 CACNA1I SLC25A28 SLC27A5

3.82e-04118015721GO:0022857
GeneOntologyBiologicalProcesscarbohydrate transport

MYC SLC25A27 UPK3B MFSD2B CAPN10 IGF1 SLC45A3 SLC35A2 ABCB11 RFT1

1.76e-0618615810GO:0008643
GeneOntologyBiologicalProcessmonocarboxylic acid metabolic process

MYC GPD1 TREX1 TIGAR ARV1 ACADS ACADVL ACAD9 UBR4 ACSL1 LDHD IGF1 MALRD1 SLC45A3 UCP2 ABCB11 SLC27A5

4.74e-0573115817GO:0032787
GeneOntologyBiologicalProcessoxoacid metabolic process

MYC GPD1 TREX1 DPYD TIGAR ARV1 ACADS ACADVL ACAD9 UBR4 PAPSS2 ACSL1 LDHD DGLUCY IGF1 MALRD1 SLC45A3 UCP2 GADL1 ABCB11 SLC27A5

5.97e-05105815821GO:0043436
GeneOntologyBiologicalProcessorganic acid metabolic process

MYC GPD1 TREX1 DPYD TIGAR ARV1 ACADS ACADVL ACAD9 UBR4 PAPSS2 ACSL1 LDHD DGLUCY IGF1 MALRD1 SLC45A3 UCP2 GADL1 ABCB11 SLC27A5

6.48e-05106415821GO:0006082
GeneOntologyBiologicalProcessossification involved in bone maturation

IGF1 ADAMTS7 DCHS1 LTF

7.78e-05301584GO:0043931
GeneOntologyBiologicalProcessregulation of steroid metabolic process

ARV1 ACADVL IGF1 MALRD1 KCNMA1 ABCB11 DDX20

8.26e-051351587GO:0019218
GeneOntologyBiologicalProcessbone maturation

IGF1 ADAMTS7 DCHS1 LTF

1.14e-04331584GO:0070977
GeneOntologyBiologicalProcessregulation of purine nucleotide catabolic process

MYC GPD1 TREX1 TIGAR IGF1

1.22e-04631585GO:0033121
GeneOntologyBiologicalProcessregulation of nucleotide catabolic process

MYC GPD1 TREX1 TIGAR IGF1

1.22e-04631585GO:0030811
GeneOntologyBiologicalProcessregulation of glycolytic process

MYC GPD1 TREX1 TIGAR IGF1

1.22e-04631585GO:0006110
GeneOntologyBiologicalProcesscarboxylic acid metabolic process

MYC GPD1 TREX1 DPYD TIGAR ARV1 ACADS ACADVL ACAD9 UBR4 ACSL1 LDHD DGLUCY IGF1 MALRD1 SLC45A3 UCP2 GADL1 ABCB11 SLC27A5

1.30e-04103515820GO:0019752
GeneOntologyBiologicalProcessregulation of small molecule metabolic process

MYC GPD1 TREX1 TIGAR ARV1 ACADVL UBR4 IGF1 MALRD1 SLC45A3 KCNMA1 ABCB11

1.34e-0443415812GO:0062012
GeneOntologyBiologicalProcessdetection of bacterial lipopeptide

TLR6 TLR1

1.74e-0431582GO:0070340
GeneOntologyBiologicalProcessanimal organ maturation

IGF1 ADAMTS7 DCHS1 LTF

1.80e-04371584GO:0048799
GeneOntologyBiologicalProcessglycolytic process

MYC GPD1 TREX1 TIGAR IGF1 UCP2

2.04e-041101586GO:0006096
GeneOntologyBiologicalProcessADP catabolic process

MYC GPD1 TREX1 TIGAR IGF1 UCP2

2.48e-041141586GO:0046032
GeneOntologyBiologicalProcesspurine nucleoside diphosphate catabolic process

MYC GPD1 TREX1 TIGAR IGF1 UCP2

2.85e-041171586GO:0009137
GeneOntologyBiologicalProcesspurine ribonucleoside diphosphate catabolic process

MYC GPD1 TREX1 TIGAR IGF1 UCP2

2.85e-041171586GO:0009181
GeneOntologyBiologicalProcesspyridine nucleotide catabolic process

MYC GPD1 TREX1 TIGAR IGF1 UCP2

3.13e-041191586GO:0019364
GeneOntologyBiologicalProcesscarbohydrate transmembrane transport

MYC SLC25A27 UPK3B CAPN10 IGF1 SLC45A3 ABCB11

3.19e-041681587GO:0034219
GeneOntologyBiologicalProcessADP metabolic process

MYC GPD1 TREX1 TIGAR IGF1 UCP2

3.27e-041201586GO:0046031
GeneOntologyBiologicalProcessribonucleoside diphosphate catabolic process

MYC GPD1 TREX1 TIGAR IGF1 UCP2

3.42e-041211586GO:0009191
GeneOntologyBiologicalProcessdetection of bacterial lipoprotein

TLR6 TLR1

3.46e-0441582GO:0042494
GeneOntologyCellularComponentmanchette

RIMBP3 RIMBP3C RIMBP3B DYNC1H1

5.58e-05281584GO:0002177
Domain-

WSB1 PLXNA3 VPS11 DCAF8 FBXW4 DYNC2I1 CFAP43 WRAP53 WDFY4 DDB2 SEMA4G WDR91 WDR38 WDHD1 RRP9 GNB1 PLXNA2

2.60e-09333155172.130.10.10
DomainWD40/YVTN_repeat-like_dom

WSB1 PLXNA3 VPS11 DCAF8 FBXW4 DYNC2I1 CFAP43 WRAP53 WDFY4 DDB2 SEMA4G WDR91 WDR38 WDHD1 RRP9 GNB1 PLXNA2

2.85e-0933515517IPR015943
DomainWD40_repeat_dom

WSB1 VPS11 DCAF8 UBR4 FBXW4 DYNC2I1 CFAP43 WRAP53 WDFY4 DDB2 WDR91 WDR38 WDHD1 RRP9 GNB1

2.73e-0829715515IPR017986
DomainWD40

WSB1 DCAF8 FBXW4 DYNC2I1 CFAP43 WRAP53 WDFY4 DDB2 WDR91 WDR38 WDHD1 RRP9 GNB1

3.81e-0726815513SM00320
DomainWD40_repeat

WSB1 DCAF8 FBXW4 DYNC2I1 CFAP43 WRAP53 WDFY4 DDB2 WDR91 WDR38 WDHD1 RRP9 GNB1

4.51e-0727215513IPR001680
DomainWD_REPEATS_1

WSB1 DCAF8 FBXW4 DYNC2I1 CFAP43 WRAP53 WDFY4 DDB2 WDR91 WDR38 WDHD1 RRP9 GNB1

5.78e-0727815513PS00678
DomainWD_REPEATS_2

WSB1 DCAF8 FBXW4 DYNC2I1 CFAP43 WRAP53 WDFY4 DDB2 WDR91 WDR38 WDHD1 RRP9 GNB1

6.02e-0727915513PS50082
DomainWD_REPEATS_REGION

WSB1 DCAF8 FBXW4 DYNC2I1 CFAP43 WRAP53 WDFY4 DDB2 WDR91 WDR38 WDHD1 RRP9 GNB1

6.02e-0727915513PS50294
DomainWD40

WSB1 DCAF8 FBXW4 DYNC2I1 WRAP53 WDFY4 DDB2 WDR91 WDR38 WDHD1 RRP9 GNB1

1.76e-0625915512PF00400
DomainAcyl-CoA_DH_CS

ACADS ACADVL ACAD9

4.54e-0591553IPR006089
DomainACYL_COA_DH_1

ACADS ACADVL ACAD9

6.45e-05101553PS00072
DomainACYL_COA_DH_2

ACADS ACADVL ACAD9

6.45e-05101553PS00073
DomainAquaporin_12

AQP12A AQP12B

6.84e-0521552IPR023265
DomainLY6G6d/LY6G6f

LY6G6F LY6G6D

6.84e-0521552IPR026524
DomainAcyl-CoA_dh_N

ACADS ACADVL ACAD9

8.81e-05111553PF02771
Domain-

ACADS ACADVL ACAD9

1.51e-041315531.10.540.10
DomainAcyl-CoA_dh_1

ACADS ACADVL ACAD9

1.51e-04131553PF00441
DomainAcylCoA_DH/ox_N

ACADS ACADVL ACAD9

1.51e-04131553IPR013786
DomainDynein_HC_stalk

DNHD1 DYNC1H1 DNAH11

1.91e-04141553IPR024743
DomainDynein_heavy_dom-2

DNHD1 DYNC1H1 DNAH11

1.91e-04141553IPR013602
DomainDHC_N2

DNHD1 DYNC1H1 DNAH11

1.91e-04141553PF08393
DomainMT

DNHD1 DYNC1H1 DNAH11

1.91e-04141553PF12777
DomainAquaporin_11/12

AQP12A AQP12B

2.04e-0431552IPR016697
DomainDHC_fam

DNHD1 DYNC1H1 DNAH11

2.37e-04151553IPR026983
DomainAcyl-CoA_Oxase/DH_cen-dom

ACADS ACADVL ACAD9

2.37e-04151553IPR006091
DomainAcylCoA_DH/oxidase_NM_dom

ACADS ACADVL ACAD9

2.37e-04151553IPR009100
DomainDynein_heavy

DNHD1 DYNC1H1 DNAH11

2.37e-04151553PF03028
DomainAcyl-CoA_dh_M

ACADS ACADVL ACAD9

2.37e-04151553PF02770
DomainDynein_heavy_dom

DNHD1 DYNC1H1 DNAH11

2.37e-04151553IPR004273
DomainIg-like_fold

PLXNA3 OBSCN SEMA4G NCR3 RIMBP3 LY6G6F ANOS1 HMCN2 BTNL3 IGHM CD101 PKHD1 RIMBP3C FCRL4 RIMBP3B PLXNA2

2.64e-0470615516IPR013783
DomainAcylCo_DH/oxidase_C

ACADS ACADVL ACAD9

2.90e-04161553IPR009075
DomainWD40_repeat_CS

WSB1 WDFY4 DDB2 WDR38 WDHD1 RRP9 GNB1

4.44e-041641557IPR019775
DomainToll-like_receptor

TLR6 TLR1

6.73e-0451552IPR017241
DomainCLTH

RMND5B RMND5A

1.00e-0361552PF10607
DomainCRA

RMND5B RMND5A

1.00e-0361552SM00757
DomainCTLH/CRA

RMND5B RMND5A

1.00e-0361552IPR024964
DomainCRA_dom

RMND5B RMND5A

1.00e-0361552IPR013144
Domain-

PLXNA3 OBSCN SEMA4G NCR3 RIMBP3 LY6G6F ANOS1 BTNL3 CD101 PKHD1 RIMBP3C FCRL4 RIMBP3B PLXNA2

1.27e-03663155142.60.40.10
DomainIPT

PLXNA3 PKHD1 PLXNA2

1.42e-03271553SM00429
DomainDHC_N1

DYNC1H1 DNAH11

1.85e-0381552PF08385
DomainVPS9

GAPVD1 RIN1

1.85e-0381552SM00167
DomainDynein_heavy_dom-1

DYNC1H1 DNAH11

1.85e-0381552IPR013594
DomainSemap_dom

PLXNA3 SEMA4G PLXNA2

2.12e-03311553IPR001627
DomainSEMA

PLXNA3 SEMA4G PLXNA2

2.12e-03311553PS51004
DomainTIG

PLXNA3 PKHD1 PLXNA2

2.12e-03311553PF01833
DomainSema

PLXNA3 SEMA4G PLXNA2

2.12e-03311553SM00630
DomainSema

PLXNA3 SEMA4G PLXNA2

2.12e-03311553PF01403
DomainIPT

PLXNA3 PKHD1 PLXNA2

2.33e-03321553IPR002909
DomainPlexin_repeat

PLXNA3 SEMA4G PLXNA2

2.33e-03321553IPR002165
DomainPSI

PLXNA3 SEMA4G PLXNA2

2.33e-03321553PF01437
DomainPlexin_cytopl

PLXNA3 PLXNA2

2.37e-0391552PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA3 PLXNA2

2.37e-0391552IPR013548
DomainCTLH

RMND5B RMND5A

2.37e-0391552SM00668
DomainPlexin

PLXNA3 PLXNA2

2.37e-0391552IPR031148
DomainCTLH_C

RMND5B RMND5A

2.95e-03101552IPR006595
DomainVPS9

GAPVD1 RIN1

2.95e-03101552PS51205
DomainVDCCAlpha1

CACNA1B CACNA1I

2.95e-03101552IPR002077
DomainVPS9

GAPVD1 RIN1

2.95e-03101552PF02204
DomainCTLH

RMND5B RMND5A

2.95e-03101552PS50897
DomainVPS9

GAPVD1 RIN1

2.95e-03101552IPR003123
DomainSH3_9

SH3RF1 RIMBP3 RIMBP3C RIMBP3B

4.04e-03781554PF14604
Domaincalpain_III

CAPN14 CAPN10

4.28e-03121552SM00720
DomainC2_III

CAPN14 CAPN10

4.28e-03121552IPR033883
DomainCalpain_III

CAPN14 CAPN10

4.28e-03121552IPR022683
DomainMit_uncoupling

SLC25A27 UCP2

4.28e-03121552IPR002030
DomainOTU

OTUD1 VCPIP1

5.03e-03131552PF02338
DomainCalpain_III

CAPN14 CAPN10

5.03e-03131552PF01067
DomainCalpain_domain_III

CAPN14 CAPN10

5.03e-03131552IPR022682
DomainG-protein_beta_WD-40_rep

WSB1 WDR38 RRP9 GNB1

5.49e-03851554IPR020472
DomainPSI

PLXNA3 SEMA4G PLXNA2

5.79e-03441553IPR016201
DomainDynein_heavy_chain_D4_dom

DYNC1H1 DNAH11

5.83e-03141552IPR024317
DomainMIP

AQP12A AQP12B

5.83e-03141552PF00230
DomainATPase_dyneun-rel_AAA

DYNC1H1 DNAH11

5.83e-03141552IPR011704
DomainMIP

AQP12A AQP12B

5.83e-03141552PS00221
DomainCalpain_cysteine_protease

CAPN14 CAPN10

5.83e-03141552IPR022684
DomainAAA_8

DYNC1H1 DNAH11

5.83e-03141552PF12780
DomainAAA_5

DYNC1H1 DNAH11

5.83e-03141552PF07728
DomainRho_GTPase_activation_prot

PLXNA3 GAPVD1 SRGAP2 PLXNA2

6.20e-03881554IPR008936
DomainPSI

PLXNA3 SEMA4G PLXNA2

6.55e-03461553SM00423
DomainOTU

OTUD1 VCPIP1

6.69e-03151552PS50802
DomainPeptidase_C2

CAPN14 CAPN10

6.69e-03151552PF00648
Domain-

AQP12A AQP12B

6.69e-031515521.20.1080.10
DomainAquaporin-like

AQP12A AQP12B

6.69e-03151552IPR023271
DomainCysPc

CAPN14 CAPN10

6.69e-03151552SM00230
DomainPeptidase_C2_calpain_cat

CAPN14 CAPN10

6.69e-03151552IPR001300
DomainMIP

AQP12A AQP12B

6.69e-03151552IPR000425
DomainCALPAIN_CAT

CAPN14 CAPN10

6.69e-03151552PS50203
DomainOTU_dom

OTUD1 VCPIP1

6.69e-03151552IPR003323
Domain-

PLXNA3 GAPVD1

7.61e-031615521.10.506.10
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

3.95e-074162319091768
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

9.85e-075162317855024
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PLXNA3 STK36 SH3RF1 UBR4 OBSCN SRGAP2 MIB2 CFAP43 MED13L WRAP53 ZZEF1 DENND1A MAP1S ADAMTS7 SLC45A3 SLC35A2 PRKDC PLEC DYNC1H1

1.07e-0611051621935748872
Pubmed

Nasopharyngeal Exposure to Streptococcus pneumoniae Induces Extended Age-Dependent Protection against Pulmonary Infection Mediated by Antibodies and CD138+ Cells.

CD93 IGHM PRKDC

1.96e-066162329661828
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

CTTNBP2 RMND5A DCAF8 NRDC UBR4 ZZEF1 PIPSL NUP160

7.38e-06212162833853758
Pubmed

Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease.

TREX1 MAVS IGHM

8.16e-069162322284419
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

GAPVD1 FAM234A QPCTL ACAD9 HS6ST2 UBR4 TMEM115 NUS1 DDX20 TIMM29 PRKDC RFT1 GNB1 ZNHIT2 DYNC1H1 VCPIP1

9.28e-069421621631073040
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DCAF8 UBR4 FBXW4 DYNC2I1 SRPK2 SRGAP2 MED13L WRAP53 MSTO1 CREBZF DGLUCY HEATR6 MAP1S PRKDC PLEC GNB1 BACE2 DYNC1H1 VCPIP1

9.39e-0612851621935914814
Pubmed

Species-specific recognition of Aspergillus fumigatus by Toll-like receptor 1 and Toll-like receptor 6.

TLR6 TLR1

2.16e-052162222315281
Pubmed

Efficient direct conversion of human fibroblasts into myogenic lineage induced by co-transduction with MYCL and MYOD1.

MYC MYOD1

2.16e-052162228501623
Pubmed

[DISTRIBUTION OF TWO-LOCUS HAPLOTYPES OF MICROBIAL COMPONENT SENSOR GENES TLR1 AND TLR6 IN MAJOR POPULATIONS OF SOUTH URALS].

TLR6 TLR1

2.16e-052162226470427
Pubmed

Uncoupling protein 2 and 4 expression pattern during stem cell differentiation provides new insight into their putative function.

SLC25A27 UCP2

2.16e-052162224523901
Pubmed

Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants.

TLR6 TLR1

2.16e-052162221852947
Pubmed

Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin.

TLR6 TLR1

2.16e-052162211123271
Pubmed

Genetic ancestry effects on the distribution of toll-like receptors (TLRs) gene polymorphisms in a population of the Atlantic Forest, São Paulo, Brazil.

TLR6 TLR1

2.16e-052162229175392
Pubmed

Nardilysin convertase regulates the function of the maxi-K channel isoform mK44 in human myometrium.

NRDC KCNMA1

2.16e-052162219118164
Pubmed

The Roles of TLR Gene Polymorphisms in Atherosclerosis: A Systematic Review and Meta-Analysis of 35,317 Subjects.

TLR6 TLR1

2.16e-052162228474755
Pubmed

Genetic analysis of the aquaporin water channels AQP12A and AQP12B in patients with chronic pancreatitis.

AQP12A AQP12B

2.16e-052162236167651
Pubmed

Abnormal mitochondrial bioenergetics and heart rate dysfunction in mice lacking very-long-chain acyl-CoA dehydrogenase.

ACADVL ACAD9

2.16e-052162216199475
Pubmed

In vitro evidence suggests that miR-133a-mediated regulation of uncoupling protein 2 (UCP2) is an indispensable step in myogenic differentiation.

MYOD1 UCP2

2.16e-052162219073597
Pubmed

Role of TLR1 and TLR6 in the host defense against disseminated candidiasis.

TLR6 TLR1

2.16e-052162218036178
Pubmed

The association of genetic variants in toll-like receptor 2 subfamily with allergy and asthma after hospitalization for bronchiolitis in infancy.

TLR6 TLR1

2.16e-052162224445834
Pubmed

IGF-1 regulate the expression of uncoupling protein 2 via FOXO1.

IGF1 UCP2

2.16e-052162232156173
Pubmed

Toll-like Receptor 1 743 A>G, 1805 T>G & Toll-like Receptor 6 745 C>T gene polymorphism and tuberculosis: a case control study of north Indian population from Agra (India).

TLR6 TLR1

2.16e-052162224984237
Pubmed

SNPs in the exons of Toll-like receptors are associated with susceptibility to type 1 diabetes in Chinese population.

TLR6 TLR1

2.16e-052162225261617
Pubmed

Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cells.

AQP12A AQP12B

2.16e-052162215809071
Pubmed

Intragenic motifs regulate the transcriptional complexity of Pkhd1/PKHD1.

PKHD1 PRKDC

2.16e-052162224984783
Pubmed

Involvement of c-Myc in the proliferation of MCF-7 human breast cancer cells induced by bHLH transcription factor DEC2.

MYC BHLHE41

2.16e-052162225524285
Pubmed

Congenital myasthenic syndrome associated with epidermolysis bullosa caused by homozygous mutations in PLEC1 and CHRNE.

CHRNE PLEC

2.16e-052162221175599
Pubmed

Pancreas-specific aquaporin 12 null mice showed increased susceptibility to caerulein-induced acute pancreatitis.

AQP12A AQP12B

2.16e-052162219726746
Pubmed

Expression of the TAF4b gene is induced by MYC through a non-canonical, but not canonical, E-box which contributes to its specific response to MYC.

MYC TAF4B

2.16e-052162219020761
Pubmed

DNA-activated protein kinase in Raji Burkitt's lymphoma cells. Phosphorylation of c-Myc oncoprotein.

MYC PRKDC

2.16e-05216221597196
Pubmed

A specific role for TLR1 in protective T(H)17 immunity during mucosal infection.

TLR6 TLR1

2.16e-052162222778390
Pubmed

DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein.

MYC PRKDC

2.16e-052162218426604
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

GPD1 SLC25A27 NRDC ACADS ACADVL ACAD9 ACSL1 LDHD DGLUCY MAVS FASTK UCP2 NAXD ALDH9A1 GTPBP3 SLC25A28

3.35e-0510471621618614015
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3 RIMBP3C RIMBP3B

3.48e-0514162317662146
Pubmed

Synergistic association of mitochondrial uncoupling protein (UCP) genes with schizophrenia.

SLC25A27 UCP2

6.45e-053162217066476
Pubmed

Disruption of the dynein-dynactin complex unveils motor-specific functions in osteoclast formation and bone resorption.

DYNC1H1 DNAH11

6.45e-053162222887640
Pubmed

A biophysical study on molecular physiology of the uncoupling proteins of the central nervous system.

SLC25A27 UCP2

6.45e-053162226182433
Pubmed

Heterozygous Arg753Gln polymorphism of human TLR-2 impairs immune activation by Borrelia burgdorferi and protects from late stage Lyme disease.

TLR6 TLR1

6.45e-053162216081826
Pubmed

Complex I assembly function and fatty acid oxidation enzyme activity of ACAD9 both contribute to disease severity in ACAD9 deficiency.

ACADVL ACAD9

6.45e-053162225721401
Pubmed

Genetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk.

TLR6 TLR1

6.45e-053162218752252
Pubmed

Sublethal infection of C57BL/6 mice with Salmonella enterica Serovar Typhimurium leads to an increase in levels of Toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs.

TLR6 TLR1

6.45e-053162215731092
Pubmed

Msh2-dependent DNA repair mitigates a unique susceptibility of B cell progenitors to c-Myc-induced lymphomas.

MYC IGHM

6.45e-053162219837692
Pubmed

IFNs activate toll-like receptor gene expression in viral infections.

TLR6 TLR1

6.45e-053162211607792
Pubmed

NANOS1 and PUMILIO2 bind microRNA biogenesis factor GEMIN3, within chromatoid body in human germ cells.

DDX20 NANOS1

6.45e-053162221800163
Pubmed

Ureaplasma parvum lipoproteins, including MB antigen, activate NF-{kappa}B through TLR1, TLR2 and TLR6.

TLR6 TLR1

6.45e-053162218451040
Pubmed

TLR1- and TLR6-independent recognition of bacterial lipopeptides.

TLR6 TLR1

6.45e-053162216455646
Pubmed

A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-kappa B through TLR1, TLR2, and TLR6.

TLR6 TLR1

6.45e-053162216177110
Pubmed

Genetic variation in the Toll-like receptor gene cluster (TLR10-TLR1-TLR6) influences disease course in sarcoidosis.

TLR6 TLR1

6.45e-053162222150367
Pubmed

Endogenous retroviruses are associated with hippocampus-based memory impairment.

MAVS IGHM

6.45e-053162231792184
Pubmed

Human acyl-CoA dehydrogenase-9 plays a novel role in the mitochondrial beta-oxidation of unsaturated fatty acids.

ACADVL ACAD9

6.45e-053162216020546
Pubmed

Resistance exercise alters MRF and IGF-I mRNA content in human skeletal muscle.

MYOD1 IGF1

6.45e-053162212716875
Pubmed

Divergent roles of amino acid residues inside and outside the BB loop affect human Toll-like receptor (TLR)2/2, TLR2/1 and TLR2/6 responsiveness.

TLR6 TLR1

6.45e-053162223626692
Pubmed

Sequence variants in Toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk.

TLR6 TLR1

6.45e-053162215812078
Pubmed

Synergistic heterozygosity in mice with inherited enzyme deficiencies of mitochondrial fatty acid beta-oxidation.

ACADS ACADVL

6.45e-053162215862275
Pubmed

RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets.

CAST CAPN10

6.45e-053162215044459
Pubmed

Epistatic effect of TLR-1, -6 and -10 polymorphisms on organic dust-mediated cytokine response.

TLR6 TLR1

6.45e-053162228123183
Pubmed

ATM-dependent spontaneous regression of early Eμ-myc-induced murine B-cell leukemia depends on natural killer and T cells.

MYC IGHM

6.45e-053162223349395
Pubmed

Impaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death.

MYC TIGAR

6.45e-053162233512431
Pubmed

Toll-like receptor 2 subfamily gene polymorphisms are associated with Bacillus Calmette-Guérin osteitis following newborn vaccination.

TLR6 TLR1

6.45e-053162225605403
Pubmed

Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1.

TLR6 TLR1

6.45e-053162214966134
Pubmed

Association between Toll-like receptor gene cluster (TLR6, TLR1, and TLR10) and prostate cancer.

TLR6 TLR1

6.45e-053162217932345
Pubmed

Toll-like receptor 2 subfamily genotypes are not associated with severity of bronchiolitis or postbronchiolitis wheezing in infants.

TLR6 TLR1

6.45e-053162224112285
Pubmed

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins.

TLR6 TLR1

6.45e-053162212077222
Pubmed

Interferon-gamma-mediated site-specific clearance of alphavirus from CNS neurons.

IGHM PRKDC

6.45e-053162211452126
Pubmed

Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling.

TLR6 TLR1

6.45e-053162218056480
Pubmed

TLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetes.

TLR6 TLR1

6.45e-053162221998742
Pubmed

Soluble Toll-like receptor 1 family members in the amniotic fluid of women with preterm prelabor rupture of the membranes.

TLR6 TLR1

6.45e-053162222280448
Pubmed

The involvement of c-Myc in the DNA double-strand break repair via regulating radiation-induced phosphorylation of ATM and DNA-PKcs activity.

MYC PRKDC

6.45e-053162226049366
Pubmed

Identification of plexin family molecules in mice.

PLXNA3 PLXNA2

6.45e-05316228806646
Pubmed

Effects of 9-ene-tetrahydrocannabinol on expression of beta-type transforming growth factors, insulin-like growth factor-I and c-myc genes in the mouse uterus.

MYC IGF1

6.45e-05316228390853
Pubmed

Polymorphisms in TLR1, TLR6 and TLR10 genes and the risk of Graves' disease.

TLR6 TLR1

6.45e-053162225028161
Pubmed

Recognition of Coxiella burnetii by toll-like receptors and nucleotide-binding oligomerization domain-like receptors.

TLR6 TLR1

6.45e-053162225246533
Pubmed

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors.

TLR6 TLR1

6.45e-053162211095740
Pubmed

[Association of polymorphisms in toll-like receptor genes with atopic dermatitis in the Republic of Bashkortostan].

TLR6 TLR1

6.45e-053162225850295
Pubmed

Toll-like receptor polymorphisms are associated with increased neurosyphilis risk.

TLR6 TLR1

6.45e-053162224922103
Pubmed

Molecular mechanisms of TLR2-mediated antigen cross-presentation in dendritic cells.

TLR6 TLR1

6.45e-053162224683188
Pubmed

Differential expression of plexin-A subfamily members in the mouse nervous system.

PLXNA3 PLXNA2

6.45e-053162211241833
Pubmed

Immunodeficient and immunosuppressed mice as models to test anti-Pneumocystis carinii drugs.

IGHM PRKDC

6.45e-05316229021175
Pubmed

Toll-like receptor 1, 2 and 6 polymorphisms: no association with 11 serum cytokine concentrations.

TLR6 TLR1

6.45e-053162230028533
Pubmed

Isolation and characterization of cDNA clones specifically expressed in testicular germ cells.

HASPIN GSG1

6.45e-05316227957958
Pubmed

Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer.

TLR6 TLR1

6.45e-053162219931471
Pubmed

Regulation of calpain activity by c-Myc through calpastatin and promotion of transformation in c-Myc-negative cells by calpastatin suppression.

MYC CAST

6.45e-053162218544539
Pubmed

Toward understanding the mechanism of ion transport activity of neuronal uncoupling proteins UCP2, UCP4, and UCP5.

SLC25A27 UCP2

6.45e-053162222524567
Pubmed

Atherosclerosis induced by endogenous and exogenous toll-like receptor (TLR)1 or TLR6 agonists.

TLR6 TLR1

6.45e-053162222822027
Pubmed

MYC Targeted Long Noncoding RNA DANCR Promotes Cancer in Part by Reducing p21 Levels.

MYC DANCR

6.45e-053162229180471
Pubmed

TLR1, TLR2, and TLR6 gene polymorphisms are associated with increased susceptibility to complicated skin and skin structure infections.

TLR6 TLR1

6.45e-053162224511099
Pubmed

Full-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease.

TLR6 TLR1

6.45e-053162218091991
Pubmed

TLR1 and TLR6 polymorphisms are associated with susceptibility to invasive aspergillosis after allogeneic stem cell transplantation.

TLR6 TLR1

6.45e-053162216461792
Pubmed

Taking the next step forward - Diagnosing inherited infantile cholestatic disorders with next generation sequencing.

PKHD1 ABCB11

6.45e-053162225771912
Pubmed

Variation in the TLR10/TLR1/TLR6 locus is the major genetic determinant of interindividual difference in TLR1/2-mediated responses.

TLR6 TLR1

6.45e-053162223151486
Pubmed

Lysine 63-linked TANK-binding kinase 1 ubiquitination by mindbomb E3 ubiquitin protein ligase 2 is mediated by the mitochondrial antiviral signaling protein.

MIB2 MAVS

6.45e-053162225142606
Pubmed

Cooperation between physiological defenses and immune resistance produces asymptomatic carriage of a lethal bacterial pathogen.

IGHM PRKDC

6.45e-053162237352357
Pubmed

Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.

TLR6 TLR1

6.45e-053162217595379
Pubmed

Toll-like receptor-1, -2, and -6 polymorphisms influence disease extension in inflammatory bowel diseases.

TLR6 TLR1

6.45e-053162216374251
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

SLC25A27 ACADS ACADVL ACAD9 MSTO1 ACSL1 LDHD DGLUCY MAVS FASTK UCP2 NAXD TIMM29 ALDH9A1 GTPBP3 SLC25A28

8.74e-0511361621634800366
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

SLC25A27 NRDC ACADS ACAD9 ACSL1 LDHD DGLUCY MAVS FASTK UCP2 NAXD ALDH9A1 GTPBP3 SLC25A28

1.18e-049261621420877624
Pubmed

Toll-like receptor heterodimer variants protect from childhood asthma.

TLR6 TLR1

1.29e-044162218547625
Pubmed

TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation.

TLR6 TLR1

1.29e-044162222198949
GeneFamilyWD repeat domain containing

WSB1 DCAF8 FBXW4 DYNC2I1 CFAP43 WRAP53 WDFY4 DDB2 WDR91 WDR38 WDHD1 RRP9 GNB1

3.94e-0926210513362
GeneFamilyAcyl-CoA dehydrogenase family

ACADS ACADVL ACAD9

3.04e-05111053974
GeneFamilySolute carriers

SLC17A2 SLC25A27 SLC10A7 SLC1A4 SLC45A3 UCP2 SLC35A2 SLC25A28 SLC27A5

4.91e-043951059752
GeneFamilyPlexins

PLXNA3 PLXNA2

1.17e-0391052683
GeneFamilyCD molecules|Toll like receptors

TLR6 TLR1

1.46e-03101052948
GeneFamilyVPS9 domain containing

GAPVD1 RIN1

1.46e-03101052928
GeneFamilyAquaporins

AQP12A AQP12B

2.90e-03141052305
GeneFamilyC2 domain containing|Calpains

CAPN14 CAPN10

3.34e-03151052975
GeneFamilyOTU domain containing

OTUD1 VCPIP1

4.29e-03171052669
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

MIB2 ZZEF1

4.81e-0318105291
CoexpressionFAN_EMBRYONIC_CTX_EX_4_EXCITATORY_NEURON

CACNA1B PLXNA3 STK36 ACADVL DYNC2I1 KCNMA1 CACNA1I PLEC HYDIN

9.74e-071661629M39026
CoexpressionNGUYEN_NOTCH1_TARGETS_DN

MYC UBR4 SRPK2 ITGA2 GNB1 DYNC1H1

1.29e-05831626M14650
CoexpressionGSE6092_IFNG_VS_IFNG_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_UP

BHLHE41 FAM234A TTYH2 MIB2 PGAP6 SESN1 MAVS ALDH9A1

1.70e-051801628M6718
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 SH3RF1 MFSD2B CD93 RIN1 ZBTB39 OIT3 DCHS1 BACE2

3.27e-081891629ce5b3d53c9a5457a5a02b221dee18334b5eaf8b7
ToppCellRA-08._Macrophage|World / Chamber and Cluster_Paper

DPYD SRGAP2 PAPSS2 WDFY4 ACSL1 KCNMA1 TET3 NCKAP1L

5.57e-0719316285fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

DPYD SRGAP2 PAPSS2 WDFY4 ACSL1 KCNMA1 TET3 NCKAP1L

5.79e-071941628ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCellLA-08._Macrophage|LA / Chamber and Cluster_Paper

DPYD SRGAP2 PAPSS2 WDFY4 ACSL1 KCNMA1 TET3 NCKAP1L

6.02e-0719516285e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CUX2 WDFY4 SLC1A4 IGHM UCP2 BANK1 NCKAP1L

1.50e-061531627c81a88d3f707487c511020d3960a1c41e706c6a0
ToppCellfacs-Marrow-KLS-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HS6ST2 TTYH2 ITGA2 TEX14 PAPSS2 OIT3 SLC45A3

1.78e-0615716273c6be6995c00c4cadbd209c66bf9a87c8c238652
ToppCellfacs-Marrow-KLS-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HS6ST2 TTYH2 ITGA2 TEX14 PAPSS2 OIT3 SLC45A3

1.78e-061571627662d5026e0e4249029fc6f3abc771d775d7bc3bb
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells-mDC|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CUX2 WDFY4 CD101 UCP2 TLR1 BANK1 NCKAP1L

2.80e-0616816272dca1c4a33b6da9357fa3b2a523af19baab1c21c
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CUX2 WDFY4 SLC1A4 CD101 UCP2 BANK1 NCKAP1L

3.03e-0617016273cbeea6bfa500928c413b1c6129f6dedc769cd1e
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells-mDC|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BHLHE41 WDFY4 SLC1A4 LRRC25 CD101 UCP2 NCKAP1L

3.27e-061721627cc0e2a45fa74ee19e41612c3615729462474003a
ToppCell10x5'-Liver-Lymphocytic_B-Memory_B_cells|Liver / Manually curated celltypes from each tissue

BHLHE41 WDFY4 SLC45A3 IGHM FCRL4 BACE2 BANK1

4.58e-061811627a9f4df288c34e3b2b6ed861ac6cda970c3ee08b1
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 SH3RF1 MFSD2B RIN1 OIT3 DCHS1 BACE2

5.47e-0618616272cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 SH3RF1 MFSD2B RIN1 OIT3 DCHS1 BACE2

5.47e-06186162790d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCell10x5'-Liver-Lymphocytic_B|Liver / Manually curated celltypes from each tissue

BHLHE41 WDFY4 SLC45A3 IGHM BACE2 BANK1 TCTN1

6.08e-0618916271ebff8185060d78f27f8d887e9adaa5f8faf2196
ToppCellCOVID-19-Heart-Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

DPYD WDFY4 DENND1A ACSL1 TLR1 TET3 NCKAP1L

6.08e-0618916272586f4088721c5debec86c2b211b739fd33713eb
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_2|356C / Donor, Lineage, Cell class and subclass (all cells)

GPD1 BHLHE41 TNFSF12 TEX14 ANOS1 IGF1 KCNMA1

6.29e-0619016274cce4ddb79b7751d0103e10f71156977e0c34439
ToppCellDendritic_cell|World / shred by cell class for nasal brushing

WDFY4 NCR3 CD93 LRRC25 KCNMA1 FCRL4 NCKAP1L

6.29e-061901627ae24934f45eea9c228bf6fe8cd0d6abca9eb208e
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DYNC2I1 CFAP43 ITGA2 HYDIN TCTN1 PLXNA2 DNAH11

6.97e-061931627ea345d34440b25f65358a53dc72831998d1c3620
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYC BHLHE41 WDFY4 IGHM TAF4B BACE2 BANK1

6.97e-0619316271b7d17ef85bbe57adfdf68b728978c4d5521a298
ToppCellcontrol-Lymphoid-B_cell|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

BHLHE41 SRGAP2 TLR6 WDFY4 TLR1 FCRL4 BANK1

7.21e-061941627a5284adca931a78b1c4592925c4860853ebd24f1
ToppCellB_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

BHLHE41 TLR6 WDFY4 IGHM TAF4B BACE2 BANK1

7.21e-06194162722b87fe2bb84632ddcef8f1d7742021728e2246d
ToppCellLA-08._Macrophage|World / Chamber and Cluster_Paper

DPYD SRGAP2 PAPSS2 WDFY4 KCNMA1 TET3 NCKAP1L

7.21e-061941627c1805572bcc11b1cd29083329d7b5911489fb758
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2 WDFY4 IGF1 TLR1 KCNMA1 TET3 NCKAP1L

7.21e-061941627c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

WDFY4 DENND1A ACSL1 TLR1 KCNMA1 TET3 NCKAP1L

7.46e-061951627148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SRGAP2 WDFY4 IGF1 TLR1 KCNMA1 TET3 NCKAP1L

7.71e-061961627cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

DPYD WDFY4 ACSL1 TLR1 KCNMA1 TET3 NCKAP1L

7.71e-0619616277026c1fc33425e5476063d17c79e4b79356a9e01
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

DPYD WDFY4 ACSL1 TLR1 KCNMA1 TET3 NCKAP1L

7.97e-061971627e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|lung / Disease (COVID-19 only), tissue and cell type

WDFY4 DENND1A ACSL1 TLR1 KCNMA1 TET3 NCKAP1L

7.97e-0619716273896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLR6 WDFY4 IGF1 LRRC25 UCP2 TLR1 NCKAP1L

8.24e-06198162788635244a0b306d2cc50b8412fe47bb359c9cf00
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TTYH2 WDFY4 DENND1A CD93 TLR1 KCNMA1 NCKAP1L

8.79e-062001627179afc4bee7a2fd85a3b5dadf32544a63807c164
ToppCellChildren_(3_yrs)-Immune-monocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DPYD SRGAP2 DENND1A ACSL1 CD93 TLR1 TET3

8.79e-062001627881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TTYH2 WDFY4 DENND1A CD93 TLR1 KCNMA1 NCKAP1L

8.79e-062001627ad52b38df5c71f28829b04cd0e6b97f0f9f7610a
ToppCellLPS-IL1RA-Myeloid-Monocytes,_Macrophages-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OTUD1 WDFY4 PGAP6 SLC35A2 BANK1 NCKAP1L

1.20e-051391626505bf5a483fc2ba69377db9850c3b26ab2f416d1
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TLR6 WDFY4 HMCN2 LRRC25 KCNMA1 NCKAP1L

1.59e-051461626b76110b159acd27a2c8d6a9f98336608ace1ec12
ToppCellLPS_only-Myeloid-Dendritic_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CUX2 TTYH2 WDFY4 SLC1A4 TLR1 NCKAP1L

1.72e-051481626cb9365663f9cba35d47b5dd9079f42e88b70d915
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-pDC|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CUX2 WDFY4 SLC1A4 IGHM BANK1 NCKAP1L

2.00e-0515216260c6dd41142e4ca1e54ca41e05e42ed29fbf0e570
ToppCellGlobus_pallidus-Hematopoietic|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TLR6 WDFY4 LRRC25 TLR1 BANK1 NCKAP1L

2.31e-05156162667cdaadc3b917f7072adce16c0391472c14a2563
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 DPYD SEMA4G ACSL1 ABCB11 SLC27A5

2.31e-051561626e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B SLC17A2 CTTNBP2 PKHD1 KCNMA1 HYDIN

2.66e-051601626c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOD1 CUBN CHRNE RIMBP3 HPX NANOS1

2.66e-051601626f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B SLC17A2 CTTNBP2 PKHD1 KCNMA1 HYDIN

2.66e-05160162625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell10x5'-bone_marrow-Lymphocytic_B-ABC_aged-B_memory|bone_marrow / Manually curated celltypes from each tissue

GPD1 BHLHE41 WDFY4 IGHM BACE2 BANK1

3.06e-051641626746833f74095c0f25ce76baf1069f1848c231933
ToppCellInfluenza_Severe-cDC|World / Disease group and Cell class

CTTNBP2 MFSD2B SLC45A3 LTF TAF4B NANOS1

3.06e-051641626c984228f73b9aa1aaf948541f64f41ed874770cd
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYC PGAP6 SEMA4G RIMBP3 WDHD1 DNAH11

3.17e-0516516261703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCellThalamus-Hematopoietic|Thalamus / BrainAtlas - Mouse McCarroll V32

WDFY4 LRRC25 IGHM BANK1 GSG1 NCKAP1L

3.28e-05166162676d60ac7ac5d1eaf530f0c741d9c48e0bd58396b
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TREX1 QPCTL NCR3 CD101 UCP2 BANK1

3.50e-051681626187b98664843a304406f086ea696adbf32283d07
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD1 SLC17A2 SEMA4G ACSL1 ABCB11 SLC27A5

3.50e-051681626b98af4043dfa5dfa4413e482879fad88de484675
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD1 SLC17A2 SEMA4G ACSL1 ABCB11 SLC27A5

3.50e-051681626073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCelldroplet-Liver-HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD1 SLC17A2 SEMA4G ACSL1 ABCB11 SLC27A5

3.62e-051691626f195467438c589f87224bde7da720dea072d110c
ToppCelldroplet-Liver-HEPATOCYTES-1m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD1 SLC17A2 SEMA4G ACSL1 ABCB11 SLC27A5

3.62e-0516916267785cab967a33560830c394c918d6ce625103858
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8|TCGA-Liver / Sample_Type by Project: Shred V9

GPD1 ADCY4 PAPSS2 LDHD HMCN2 HPX

3.87e-051711626c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCellfacs-Heart-LV-3m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYC MYOD1 HASPIN DANCR CACNA1I BANK1

3.87e-051711626c6fc9ef9735dbf5314a4c7dac2b2954b0985ae4d
ToppCellfacs-Heart-LV-3m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYC MYOD1 HASPIN DANCR CACNA1I BANK1

3.87e-05171162655b194a9bf4d3e4b5d96e0d1298424359c441cbb
ToppCell10x5'-Liver-Lymphocytic_B-ABC_aged-B_memory|Liver / Manually curated celltypes from each tissue

BHLHE41 WDFY4 IGHM FCRL4 BACE2 BANK1

3.87e-051711626eb47f4a09a630ed14a0898377039ed50ef7cc292
ToppCellInfluenza_Severe-B_intermediate|World / Disease group and Cell class

BHLHE41 WDFY4 IGHM FCRL4 BACE2 BANK1

3.87e-0517116264d33e1dc1efc423dbdd5f4cca6d6440a68add8d0
ToppCellPND07-28-samps-Myeloid-Macrophage-CD163+_Macrophage|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SRGAP2 SESN1 LRRC25 TLR1 BANK1 NCKAP1L

4.00e-0517216269a659442dc41bd2a4361a7e38a7ee37a39781667
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-Mast_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTTNBP2 MFSD2B WDR91 ADAMTS7 SLC45A3 BACE2

4.69e-0517716260176ffa5e66fa684d0a8264af0db8f77fc391afd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 EYA1 GADL1 PKHD1 HYDIN DNAH11

4.69e-051771626da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-9|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STK36 QPCTL IGHM BACE2 BANK1 TCTN1

4.69e-051771626ae55773c531099a9e94f44f01ba48b5e71dddc53
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BHLHE41 WDFY4 IGHM FCRL4 BACE2 BANK1

4.84e-051781626be1d991c5a0a5be22f14f57d34ee1330f1a12963
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 EYA1 ZBTB39 PKHD1 HYDIN DNAH11

4.84e-051781626c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYC WDFY4 IGHM TAF4B BACE2 BANK1

4.99e-051791626a28a1de500a74c6dcc43481abf9ec0f7e7a300a9
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WDFY4 IGHM UCP2 FCRL4 BANK1 NCKAP1L

5.31e-051811626e7d9910f6143055645b6f03b1018282e6c215f10
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TREX1 TNFSF12 OTUD1 ACSL1 CD93 TLR1

5.47e-05182162616186b7a0c33caa48631962381e3ab7e5d166163
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 CFAP43 EYA1 GADL1 HYDIN DNAH11

5.64e-051831626cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 OBSCN PKD1L2 PKHD1 HYDIN DNAH11

5.81e-0518416262cbed6462fea2622871bb7e49b0df3d984239281
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-FCRL4+_Memory_B|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BHLHE41 WDFY4 IGHM UCP2 FCRL4 BANK1

5.81e-05184162695cf125127658c4c04445c61809d1aed21ee1f83
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 OBSCN PKD1L2 PKHD1 HYDIN DNAH11

5.81e-051841626ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 OBSCN PKD1L2 PKHD1 HYDIN DNAH11

5.81e-0518416262b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell5'-Adult-SmallIntestine-Hematopoietic-B_cells-Naive_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OTUD1 WDFY4 NCR3 IGHM BANK1 TCTN1

5.81e-051841626a068ae741889d59937690c11e0bf405481402c25
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MED13L CD93 PKHD1 KCNMA1 PLEC TET3

6.17e-05186162623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellsevere_influenza-B_intermediate|severe_influenza / disease group, cell group and cell class (v2)

BHLHE41 WDFY4 IGHM FCRL4 BACE2 BANK1

6.36e-051871626d6db8595aa72fdabc4a056ba6ce09876868a66d5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 HS6ST2 ITGA2 PAPSS2 PKHD1 KCNMA1

6.36e-05187162677886f99c229610abd28c4c370d2c7d1536c9782
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 CAPN14 ITGA2 EYA1 PKHD1 KCNMA1

6.36e-051871626f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellMonocytes-M2-like_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

CTTNBP2 QPCTL SESN1 ANOS1 IGF1 FASTK

6.36e-05187162659e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCellfacs-Heart-RA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 OTUD1 EYA1 CD93 SLC45A3 BACE2

6.55e-0518816264ddb11a90bf3baa7237bde304db44dfcc56aed52
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WDFY4 NCR3 IGHM UCP2 FCRL4 BANK1

6.55e-0518816267b56c680e9f1851cb961b0f8faeeb987685ae36d
ToppCellfacs-Heart-RA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 OTUD1 EYA1 CD93 SLC45A3 BACE2

6.55e-051881626e47e66906922d5c69b1aafe28face0787d3fc563
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BHLHE41 WDFY4 IGHM FCRL4 BACE2 BANK1

6.55e-05188162618d16e3f095a109b6a690f46fe7fcd5674c3636b
ToppCell10x5'-blood-Lymphocytic_B-Naive_B_cells|blood / Manually curated celltypes from each tissue

WDFY4 SESN1 IGHM BACE2 BANK1 TCTN1

6.55e-0518816262b3560b28f9df6f4d4a3e0a4acfa6c7d964ad0fe
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CTTNBP2 MFSD2B ELSPBP1 SLC45A3 GADL1 BACE2

6.74e-051891626aba941ba6ce7702418b3f470bde573d123c4aade
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 CFAP43 EYA1 PKHD1 HYDIN DNAH11

6.74e-051891626904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 CAPN14 ITGA2 EYA1 PKHD1 KCNMA1

6.74e-051891626e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellLV-08._Macrophage|World / Chamber and Cluster_Paper

DPYD SRGAP2 WDFY4 KCNMA1 TET3 NCKAP1L

7.15e-051911626e7a0bc46ba9ba772636a583f3387748418e18832
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

GPD1 BHLHE41 TEX14 ANOS1 IGF1 MALRD1

7.15e-0519116262b10a73c5d80e83d67a7121fb004a1aa86a537ef
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GPD1 BHLHE41 TEX14 ANOS1 IGF1 MALRD1

7.15e-05191162602e1ae144da7274171e055356d10e8d175c5347f
ToppCellfacs-Heart-RV-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 OTUD1 EYA1 CD93 ZBTB39 BACE2

7.15e-051911626f0c649bb32732c9dd38a0af8ce94d2a4d16de39a
ToppCellSevere_COVID-19-Myeloid-TRAM3|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

GPD1 BHLHE41 TEX14 ANOS1 IGF1 MALRD1

7.15e-05191162605867b96199a46a415848409130697c810d18937
ToppCellBAL-Severe-Myeloid-TRAM|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

GPD1 BHLHE41 TEX14 ANOS1 IGF1 MALRD1

7.15e-0519116264c4f50a502e3f6768a89df686fa2830b83b8b33f
ToppCellfacs-Heart-RV-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 OTUD1 EYA1 CD93 ZBTB39 BACE2

7.15e-051911626e518c598719119e60c76016c586b1520c258bbcb
ToppCellBAL-Severe-Myeloid-TRAM|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPD1 BHLHE41 TEX14 ANOS1 IGF1 MALRD1

7.15e-051911626de7c88bb46f794291025ef121a89fcd94dea4ffe
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TREX1 TNFSF12 SRGAP2 IGF1 LRRC25 KCNMA1

7.15e-051911626b5715eeb72a97b7bc87b83f6c289e225f58da842
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

DPYD SRGAP2 WDFY4 KCNMA1 TET3 NCKAP1L

7.35e-051921626a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 EYA1 CD93 ZBTB39 SLC45A3 BACE2

7.35e-05192162614a816ef116aa992f86edab411f043cf7d07fe04
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CTTNBP2 MFSD2B ELSPBP1 SLC45A3 GADL1 BACE2

7.35e-051921626690cf19e9b0b2ada80097c63eae827529aa5b6f3
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPD1 BHLHE41 TEX14 ANOS1 IGF1 MALRD1

7.35e-05192162634505a13b8a47c9286c560122fa7861b9c331a08
ToppCellCOVID-19-Myeloid-TRAM1|COVID-19 / Condition, Lineage and Cell class

GPD1 TEX14 ANOS1 IGF1 MALRD1 CD101

7.35e-05192162652b8578699325b0d35a2d3ba36772096130ccc0c
ToppCellBAL-Severe-Myeloid-TRAM-TRAM3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPD1 BHLHE41 TEX14 ANOS1 IGF1 MALRD1

7.35e-05192162657c1410ebf90c230993e065eb78385daa3360960
ToppCellLV-08._Macrophage|LV / Chamber and Cluster_Paper

DPYD SRGAP2 WDFY4 KCNMA1 TET3 NCKAP1L

7.35e-0519216267be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CTTNBP2 MFSD2B ELSPBP1 SLC45A3 GADL1 BACE2

7.35e-0519216263d6c4c5847ca1e44fa380403d25af45d5b51ee9b
ComputationalGenes in the cancer module 184.

DPYD ACADS ACADVL ACSL1 ALDH9A1

4.38e-0629935MODULE_184
ComputationalIron ion homeostasis.

MYC HPX LTF

7.20e-0510933MODULE_540
ComputationalFatty acid metabolism.

DPYD ACADVL ACSL1 ALDH9A1

1.21e-0430934MODULE_221
ComputationalGenes in the cancer module 294.

DPYD ACADS ACADVL

4.66e-0418933MODULE_294
Drugractopamine

PLXNA3 CAST IGF1 MLC1 UCP2

7.17e-07251585CID000056052
Drugsakyomicin A

GPD1 DPYD ACADVL MYOD1 ACAD9 UCP2

1.99e-06541586CID000124041
DiseaseIntellectual Disability

CACNA1B TREX1 CUX2 MED13L SLC1A4 CAPN10 SLC35A2 GNB1 TET3 TCTN1 DYNC1H1

2.61e-0544715511C3714756
Diseaselactotransferrin measurement

ACCS LTF

1.63e-0441552EFO_0020526
Diseasechronic obstructive pulmonary disease, interleukin-8 measurement

EYA1 HYDIN

1.63e-0441552EFO_0000341, EFO_0004811
Diseaseglucose measurement

FAM234A CUX2 QPCTL CAST SESN1 ACSL1 ABCB11 CACNA1I NUP160

1.91e-043801559EFO_0004468
Diseasebombesin receptor-activated protein C6orf89 measurement

CUBN IGHM

2.71e-0451552EFO_0801428
Diseasewhole-brain volume

CUBN DNAH11

2.71e-0451552EFO_0005089
DiseaseDrug-Induced Liver Disease

GPD1 SLC10A7 ACSL1 IGF1 HPX PRKDC LTF ALDH9A1 TCTN1

3.00e-044041559C0860207
DiseaseDrug-Induced Acute Liver Injury

GPD1 SLC10A7 ACSL1 IGF1 HPX PRKDC LTF ALDH9A1 TCTN1

3.00e-044041559C3658290
DiseaseHepatitis, Toxic

GPD1 SLC10A7 ACSL1 IGF1 HPX PRKDC LTF ALDH9A1 TCTN1

3.00e-044041559C0019193
DiseaseChemically-Induced Liver Toxicity

GPD1 SLC10A7 ACSL1 IGF1 HPX PRKDC LTF ALDH9A1 TCTN1

3.00e-044041559C4279912
DiseaseChemical and Drug Induced Liver Injury

GPD1 SLC10A7 ACSL1 IGF1 HPX PRKDC LTF ALDH9A1 TCTN1

3.00e-044041559C4277682
DiseaseHepatitis, Drug-Induced

GPD1 SLC10A7 ACSL1 IGF1 HPX PRKDC LTF ALDH9A1 TCTN1

3.00e-044041559C1262760
Diseasegrowth differentiation factor 15 measurement

WDFY4 LRRC25

5.66e-0471552EFO_0009181
DiseaseC-reactive protein measurement

DPYD CUX2 ACADS CAST MFSD2B MIB2 ZZEF1 DDB2 LRRC25 ABCB11 DDX20 TIMM29 QSER1 TAF4B BANK1 DNAH11

6.35e-04120615516EFO_0004458
Diseaseaspergillosis (is_implicated_in)

TLR6 TLR1

7.52e-0481552DOID:13564 (is_implicated_in)
DiseaseAutistic behavior

CUX2 TET3

7.52e-0481552C0856975
Diseasepropionylcarnitine measurement

MALRD1 TAF4B

9.63e-0491552EFO_0020942
Diseaseaspartate aminotransferase measurement

CUX2 TNFSF12 CAST OBSCN EYA1 CUBN WDR91 DGLUCY HMCN2 BAZ2A ABCB11 NUP160 BANK1

1.01e-0390415513EFO_0004736
Diseaseimmunoglobulin isotype switching measurement

CUX2 UBR4 TLR1

1.61e-03441553EFO_0010128
Diseaseepilepsy (implicated_via_orthology)

CACNA1B SLC1A4 NUS1 KCNMA1 DYNC1H1

1.74e-031631555DOID:1826 (implicated_via_orthology)
DiseasePrimary Ciliary Dyskinesia

STK36 HYDIN DNAH11

1.95e-03471553C4551720
Diseasemelanoma

MAGEA1 UBR4 CUBN DDB2 RIN1 NUS1

2.05e-032481556C0025202
Diseasebreast cancer (biomarker_via_orthology)

MYC IGF1

2.06e-03131552DOID:1612 (biomarker_via_orthology)
Diseasecortisol measurement, response to corticosteroid, response to synacthen

ELSPBP1 NANOS1

2.06e-03131552EFO_0005843, EFO_0009175, GO_0031960
DiseaseMetabolic Bone Disorder

IGF1 KCNMA1

2.39e-03141552C0005944
DiseaseDNA methylation

DNHD1 DPYD EYA1 ACSL1 CD93 TLR1 PKHD1 KCNMA1 DCHS1 DNAH11

2.54e-0365615510GO_0006306
DiseaseProteinuria

CUBN ADAMTS7

2.75e-03151552HP_0000093
DiseaseOsteopenia

IGF1 KCNMA1

2.75e-03151552C0029453
DiseasePeripheral Nervous System Diseases

CACNA1B DPYD IGF1

2.90e-03541553C4721453
Diseasemetabolite measurement

ACADS ACADVL PKD1L2 WDFY4 SLC1A4 WDHD1 RFXANK GADL1 ALDH9A1

2.92e-035601559EFO_0004725
Diseasenervousness

DENND1A NUP160

3.13e-03161552NCIT_C74532
DiseaseMAJOR AFFECTIVE DISORDER 2

CUX2 MLC1

3.54e-03171552C1839839
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

TLR6 TLR1

3.54e-03171552DOID:8677 (biomarker_via_orthology)
Diseaseblood osmolality measurement

CUX2 PKD1L2 PKHD1

3.55e-03581553EFO_0007967
DiseaseBipolar Disorder

BHLHE41 CACNA1B CUX2 ACADS SRPK2 IGF1 MLC1 UCP2

3.83e-034771558C0005586
Diseasesystemic lupus erythematosus (is_implicated_in)

TREX1 CAST BANK1

4.29e-03621553DOID:9074 (is_implicated_in)
Diseaseresponse to methotrexate, juvenile idiopathic arthritis

CTTNBP2 CACNA1I

4.42e-03191552EFO_0002609, GO_0031427
Diseasehydrocephalus (implicated_via_orthology)

STK36 HYDIN

4.42e-03191552DOID:10908 (implicated_via_orthology)
Diseasesuperior temporal gyrus volume measurement

CTTNBP2 CUBN

4.42e-03191552EFO_0010331
Diseasenon-high density lipoprotein cholesterol measurement

SLC17A2 PLXNA3 NRDC EYA1 MIDEAS OIT3 ABCB11 GTPBP3 HYDIN DNAH11

4.56e-0371315510EFO_0005689
DiseaseMalignant Neoplasms

MYC DPYD MYOD1 LTF

4.72e-031281554C0006826
Diseasenon-alcoholic fatty liver disease (biomarker_via_orthology)

ACADVL IGF1 UCP2

4.89e-03651553DOID:0080208 (biomarker_via_orthology)
Diseasehippocampal volume

DYNC2I1 MED13L ABCB11 PLEC PLXNA2 DNAH11

4.95e-032971556EFO_0005035

Protein segments in the cluster

PeptideGeneStartEntry
IESPAFSTLRGCLTD

BANK1

661

Q8NDB2
VDEGFSSPCTFAAAV

FAM234A

126

Q9H0X4
TAFLPCTVGDASACL

BRINP3

436

Q76B58
VGFAASPCAEIAGAA

BACE2

426

Q9Y5Z0
AVFSCSLFPETSAEA

BTNL3

36

Q6UXE8
AFEPATGRVIATFTC

ALDH9A1

31

P49189
LATVLACCPSSLSAA

CFAP43

431

Q8NDM7
PALAASVTFACSGHT

AQP12A

201

Q8IXF9
TPFTSGDKIGCFALS

ACADS

141

P16219
ASLFSALATVLCEAG

ACCS

171

Q96QU6
AAAAAAFPCLSSVLS

BHLHE41

406

Q9C0J9
APEDLAVICFTSGTT

ACSL1

266

P33121
LPSGAFSDCLTIVEF

BAZ2A

846

Q9UIF9
LASPSSCNFLATVVA

GTPBP3

341

Q969Y2
PACGLKLSAFAAVSS

GSG1

181

Q2KHT4
SLLAFAPVCGQSAAA

FCRL4

6

Q96PJ5
AAFCLTEPASGSDAA

ACAD9

176

Q9H845
SLEAVPFASAANVAC

CD93

211

Q9NPY3
GEFLESTSPACLVFS

DNAH11

91

Q96DT5
ASPCLEAFATGRAAA

ABCB11

376

O95342
TSDPSFLTTVLCALG

ADCY4

56

Q8NFM4
GPASISCASFLARLG

DPYD

196

Q12882
AADSSLFCDLSTPLA

CAPN10

21

Q9HC96
ADILSSKGFPAECIS

DDX20

326

Q9UHI6
CLAGALADFTTSLLG

DNHD1

4051

Q96M86
PALAASVTFACSGHT

AQP12B

201

A6NM10
FTLCSGPRLEAALAS

CUX2

291

O14529
LCAVGSPFARASLKS

CACNA1B

441

Q00975
SLSAGVARADAPLCS

DANCR

81

P0C864
SCSINEDTGLPLAFT

ADAMTS7

371

Q9UKP4
TAAFCQSLGAAAPEV

CHRNE

406

Q04844
GCLFEDTSFPATLSS

CAPN14

41

A8MX76
PGGSRASLALCAFVA

CECR9

56

P0C854
HSLALFATSVSPCDG

C17orf113

216

A0A1B0GUU1
ALGIFPCLASAAEAL

R3HCC1

356

Q9Y3T6
FVGATDSAVPCALLL

QPCTL

181

Q9NXS2
AATAAACGVTPTDFS

QSER1

856

Q2KHR3
AFCLGATLGTAFLTE

RFT1

506

Q96AA3
GLLSTHASSLDCFAP

RIMBP3B

276

A6NNM3
GLLSTHASSLDCFAP

RIMBP3C

276

A6NJZ7
CSPAAGSFTTLVAQV

LY6G6F

51

Q5SQ64
SFSLAASIDASPALC

LY6G6F

211

Q5SQ64
DFLLCASSSGAVLPV

FASTK

431

Q14296
APEKASGFAAACVES

ANOS1

136

P23352
SGFTPADTVAIIFCS

SLC10A7

261

Q0GE19
CFLQVTATDADSGPF

DCHS1

596

Q96JQ0
ADAGLVCITSFISPF

PAPSS2

111

O95340
SSCFEVVSGAAAPAS

OTUD1

76

Q5VV17
PSAGAERTLASVCAL

MAP1S

401

Q66K74
GISAADSPSILSACL

MED13L

1936

Q71F56
EGPSTSCILESLFRA

MAGEA1

86

P43355
PFSGCFEDLAISAST

MAVS

431

Q7Z434
LSSAFVGLSFPTVCE

KCNMA1

606

Q12791
PFACGTAFAVSVLDS

KCNMA1

1031

Q12791
EIRTLEGSSAFLPCS

NCR3

26

O14931
TCLAESPAGAIEKSF

HMCN2

3571

Q8NDA2
AFLEVSCAPGLASAT

LRRC25

151

Q8N386
LALCSADSVAFPVLT

GAPVD1

1126

Q14C86
SSPSRASVCGIFVDF

DYNC2I1

456

Q8WVS4
VLLGCAPAAAAAATT

NANOS1

161

Q8WY41
PDLSAGIACAFGNLT

PLXNA2

586

O75051
PDLSAGVSCAFEAAA

PLXNA3

566

P51805
VSGLESLVESCFATP

OIT3

426

Q8WWZ8
VESIPVFGALCSSSS

MSTO1

501

Q9BUK6
VDLTAPDGSLCSFAT

MYOD1

11

P15172
PCTFLSAGEDAVVFT

DCAF8

296

Q5TAQ9
CRAASAAVLAPLGFT

NUS1

41

Q96E22
TDGFPAAATSANLCL

EYA1

406

Q99502
SACDALSSILPEAFS

HEATR6

791

Q6AI08
AGAVAAAATTPLDVC

SLC25A28

271

Q96A46
TNGSSPLLVAAFGAC

NAXD

296

Q8IW45
TLSIFELASAAGVGC

NCKAP1L

956

P55160
SAVGCFPEASIRLFA

RSKR

196

Q96LW2
CSSSPTGDFVDASVL

EP400P1

151

Q6ZTU2
GACALGISTLSLEFS

MFSD2B

426

A6NFX1
TVAFSAVAALTACRP

PGAP6

291

Q9HCN3
VNAACFSPDGARLLT

DDB2

291

Q92466
TGVCSDISPDFQLSA

ITGA2

146

P17301
FASFSLPVDGTEVTC

ITGA2

851

P17301
GAAAVAAFSCSVAPA

INSM2

141

Q96T92
FCLNSPALDTAAAAG

TENT4A

21

Q5XG87
PLIELCSSGASGSLF

PIPSL

116

A2A3N6
APEEGTVLTSFAIFC

PKD1L2

781

Q7Z442
FTCTLSEAVPVGEAS

OBSCN

4451

Q5VST9
IAIDDISFSSGCLPA

MALRD1

216

Q5VYJ5
VDSDAPILSKFCGTS

CUBN

2286

O60494
EAPAQGFSASFVSRC

CUBN

2906

O60494
TSALGACFVFSPKEG

HYDIN

501

Q4G0P3
AFLCKAGGAESPLSV

CD101

431

Q93033
SATITCLVTGFSPAD

IGHM

346

P01871
SLAPDTRLFVSGACD

GNB1

191

P62873
VDGVAATPTAASASC

ARV1

16

Q9H2C2
SIDLTVAPAGCAVSA

CTTNBP2

616

Q8WZ74
VAPAGCAVSALATSQ

CTTNBP2

621

Q8WZ74
DLGECFFPLSSTAVS

CACNA1I

1901

Q9P0X4
AATCAFPSVQAAVDS

LDHD

271

Q86WU2
AIDALSSDFTCGSPT

CAST

231

P20810
AISPLLSSFVTGTAC

FBXW4

251

P57775
IAFAKLFCSGPVSSA

GPD1

236

P21695
LFCSGPVSSATFLES

GPD1

241

P21695
PVSSATFLESCGVAD

GPD1

246

P21695
TSACLVAASAVPSGL

HASPIN

191

Q8TF76
DLLTAACSSIFPGAG

MIDEAS

771

Q6PJG2
FASGLLLSSAGFCAP

DENND1A

866

Q8TEH3
SFCADTRISALVPGF

ELSPBP1

166

Q96BH3
STIAGDCLLSAAFIA

DYNC1H1

3501

Q14204
SSLAGAACAPLFALL

HS6ST2

76

Q96MM7
ALCLLTFTSSATAGP

IGF1

36

P05019
KEGAAPFLVCATSGT

GADL1

261

Q6ZQY3
SLGAVSSCETPLAFA

DGLUCY

231

Q7Z3D6
DACVLAGRPLVSASA

MOCS3

191

O95396
AADGSDTVVLSLFPC

RFXANK

31

O14593
PGSAELTVGAAVACF

MIB2

741

Q96AX9
PGSSSSLCIVNDELF

NXF2

526

Q9GZY0
APAGILAAAATALTC

LY6G6D

111

O95868
ILDSVDAAFICPGSS

HPX

356

P02790
LPAVTFGETSGAAIC

TAF4B

466

Q92750
FGETSGAAICLPSVK

TAF4B

471

Q92750
SAAFCSLLAPERQVG

RIN1

351

Q13671
GSPSNCLETSLAEIF

TIGAR

156

Q9NQ88
LSVESPLSVSFSAGC

RMND5A

276

Q9H871
SLASFTFGCGISPEI

SESN1

211

Q9Y6P5
ELTAAHSLCFSPDGS

WRAP53

276

Q9BUR4
FIGAGSPSLVKACDS

TEX14

1291

Q8IWB6
LLGGAAACFTLAPSE

TIMM29

66

Q9BSF4
AAVARFFSASCVPGA

LTF

166

P02788
GLLSTHASSLDCFAP

RIMBP3

276

Q9UFD9
LSAAASECIDPSVVF

MYC

181

P01106
GAPCRVLANATVSAF

PKHD1

1771

P08F94
LSSDGEALFALPCAS

NUP160

221

Q12769
LASVAAFPVAAGATC

SLC45A3

356

Q96JT2
AFPVAAGATCLSHSV

SLC45A3

361

Q96JT2
GAISSALAAICTAPV

STK36

656

Q9NRP7
AGLAAVVASCLSSGF

SLC35A2

201

P78381
TDLPGCGSFSSLSVL

TLR1

481

Q15399
AISISRASAPLACAA

SH3RF1

646

Q7Z6J0
ASGETVAAFCLTEPS

ACADVL

206

P49748
VAAFCLTEPSSGSDA

ACADVL

211

P49748
PTATVKFLGAGTAAC

UCP2

11

P55851
AFGAGFCTTVIASPV

UCP2

221

P55851
LPSSVGLACFGTAAV

nan

106

Q8N377
ATPASGSAASKFLCL

VPS11

31

Q9H270
ALLAACTFGSSELLA

TMEM54

126

Q969K7
LCAAIDAEAFTLPTS

SEMA4G

141

Q9NTN9
ESPLSVSFASGCVAL

RMND5B

281

Q96G75
DLGATCVLAPKFSTS

SLC27A5

351

Q9Y2P5
CLVVTPDDSAIFSAA

RRP9

151

O43818
GLLAPFATAFATCSS

SLC1A4

331

P43007
AAVATSDFCVAPDTF

TTYH2

266

Q9BSA4
PKDIFLASASCDGSV

WDHD1

146

O75717
SASTAGDIACAFRPV

SRGAP2

1011

O75044
SLFSGSLEPVACGSV

SRPK2

456

P78362
LSFAVDTGCLAVTPG

TMEM115

36

Q12893
SGVLSSLPFIAAASC

SLC17A2

311

O00624
SLPFIAAASCTILGG

SLC17A2

316

O00624
DFSVFSACSVPVVTG

TCTN1

101

Q2MV58
EAAAAPSLANISCFT

WDFY4

1951

Q6ZS81
AATCSLPSDLTRAAA

CREBZF

26

Q9NS37
SGCAATVAELATFPL

SLC25A27

26

O95847
SAAALCVGVGSFADP

NRDC

211

O43847
SSGSEAAVPSVCFLV

PLEC

981

Q15149
AIVPDKLSSFGASCL

TET3

1466

O43151
ARLFFPASGSVSIEC

VCPIP1

56

Q96JH7
TDLPGCGSFSSLSVL

TLR6

486

Q9Y2C9
AALLSLDPAAVSAGC

PRKDC

2866

P78527
GLFSGAASPELKCAA

ZBTB39

441

O15060
CAFTPDGKILVSGAA

WDR38

281

Q5JTN6
LLSDFCATLLGVSGA

ZNHIT2

236

Q9UHR6
ACSLVPGFTDIFSES

ZZEF1

161

O43149
CLEEFSATAASSLGP

TNFSF12

191

O43508
ACDFSPDGALLATAS

WSB1

261

Q9Y6I7
SSLEALESCFAVGPI

UBR4

2481

Q5T4S7
LGLTSALDGAFCVDS

TREX1

141

Q9NSU2
PRCVFDGLASASDTV

UPK3B

111

Q9BT76
VCSAAAPSLTSQVDF

WDR91

511

A4D1P6
AAGSCIPSAIVSFTV

MLC1

86

Q15049