Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	UBA5 ABCA2 ABCA4 MCM8 MYO7B LONP2 MYO9A ABCA13 NAIP MCM2 MYO5C ATP6V1H IQCA1 RALBP1 MYO3B DNAH17 ERCC6L2 ATP2B1	1.37e-05	614	182	18	GO:0140657
GeneOntologyMolecularFunction	recombination hotspot binding	PRDM7 PRDM9	8.26e-05	2	182	2	GO:0010844
GeneOntologyMolecularFunction	enzyme regulator activity	DOCK2 ABCA2 GARNL3 RASA1 KALRN MYO9A RAPGEF5 CST9L TOM1L1 CD109 NAIP ARHGEF38 PPP2R3B APBA3 RALGAPA2 PLEKHG1 NCOR1 SERPINA1 ATP6V1H SERPINI1 RALBP1 SIPA1L1 EIF2B2 MOB3C MOB3B DMPK VAV1 SFN	8.70e-05	1418	182	28	GO:0030234
GeneOntologyMolecularFunction	dynactin binding	HOOK3 SNX6 SNX5	1.54e-04	12	182	3	GO:0034452
GeneOntologyMolecularFunction	microfilament motor activity	MYO7B MYO9A MYO5C MYO3B	3.87e-04	38	182	4	GO:0000146
GeneOntologyMolecularFunction	myosin light chain kinase activity	MYLK3 MYLK4	4.90e-04	4	182	2	GO:0004687
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA2 ABCA4 ABCA13 ATP6V1H RALBP1 ATP2B1	4.92e-04	109	182	6	GO:0042626
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO7B MYO9A MYO5C DNAI1 MYO3B DNAH17	7.48e-04	118	182	6	GO:0003774
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DOCK2 GARNL3 RASA1 KALRN MYO9A RAPGEF5 ARHGEF38 RALGAPA2 PLEKHG1 RALBP1 SIPA1L1 EIF2B2 VAV1	7.91e-04	507	182	13	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DOCK2 GARNL3 RASA1 KALRN MYO9A RAPGEF5 ARHGEF38 RALGAPA2 PLEKHG1 RALBP1 SIPA1L1 EIF2B2 VAV1	7.91e-04	507	182	13	GO:0030695
GeneOntologyMolecularFunction	short-chain fatty acid transmembrane transporter activity	SLC22A25 CD36	8.11e-04	5	182	2	GO:0015636
GeneOntologyCellularComponent	brush border	MYO7B CAPZA2 SI ADD3 SLC9A2 CD36 PLD2 PLEC SNX5	7.60e-06	152	182	9	GO:0005903
GeneOntologyCellularComponent	cluster of actin-based cell projections	MYO7B CAPZA2 SI ADD3 SLC9A2 CD36 MYO3B PLD2 PLEC SNX5	2.70e-05	223	182	10	GO:0098862
Domain	FAT	SMG1 ATR TRRAP	1.75e-05	6	181	3	PS51189
Domain	FATC	SMG1 ATR TRRAP	1.75e-05	6	181	3	PS51190
Domain	FATC_dom	SMG1 ATR TRRAP	1.75e-05	6	181	3	IPR003152
Domain	PIK_FAT	SMG1 ATR TRRAP	1.75e-05	6	181	3	IPR014009
Domain	FATC	SMG1 ATR TRRAP	1.75e-05	6	181	3	SM01343
Domain	ARM-type_fold	DOCK2 SMG1 ATR USP9Y ARMCX2 RALGAPA2 TRRAP LYST FOCAD RIF1 IFRD1 ATP6V1H WDFY3	2.76e-05	339	181	13	IPR016024
Domain	SNO	SBNO2 SBNO1	9.34e-05	2	181	2	IPR026741
Domain	SBNO_Helicase_C_dom	SBNO2 SBNO1	9.34e-05	2	181	2	IPR026937
Domain	Helicase_C_4	SBNO2 SBNO1	9.34e-05	2	181	2	PF13871
Domain	Rap_GAP	GARNL3 RALGAPA2 SIPA1L1	1.02e-04	10	181	3	PF02145
Domain	Rap_GAP_dom	GARNL3 RALGAPA2 SIPA1L1	1.39e-04	11	181	3	IPR000331
Domain	RAPGAP	GARNL3 RALGAPA2 SIPA1L1	1.39e-04	11	181	3	PS50085
Domain	Spectrin_repeat	KALRN SPTBN1 DST PLEC	1.68e-04	29	181	4	IPR002017
Domain	ABC_A	ABCA2 ABCA4 ABCA13	1.85e-04	12	181	3	IPR026082
Domain	SPEC	KALRN SPTBN1 DST PLEC	2.48e-04	32	181	4	SM00150
Domain	Spectrin/alpha-actinin	KALRN SPTBN1 DST PLEC	2.48e-04	32	181	4	IPR018159
Domain	PH_dom-like	RASA1 KALRN MYO7B SPTBN1 MTMR1 APBA3 LYST PLEKHG1 MTMR6 PLCL2 WDFY3 PLD2 VAV1	2.73e-04	426	181	13	IPR011993
Domain	SNX5/SNX6/SNX32	SNX6 SNX5	2.78e-04	3	181	2	IPR014637
Domain	VPS13	VPS13C VPS13D	2.78e-04	3	181	2	IPR026847
Domain	VPS13_mid_rpt	VPS13C VPS13D	2.78e-04	3	181	2	PF16910
Domain	VPS13	VPS13C VPS13D	2.78e-04	3	181	2	PF16908
Domain	VPS13_N2	VPS13C VPS13D	2.78e-04	3	181	2	IPR031646
Domain	VPS13_mid_rpt	VPS13C VPS13D	2.78e-04	3	181	2	IPR031642
Domain	ARM-like	DOCK2 SMG1 ATR USP9Y ARMCX2 TRRAP RIF1 IFRD1 ATP6V1H WDFY3	3.13e-04	270	181	10	IPR011989
Domain	-	SMG1 ATR TRRAP	4.57e-04	16	181	3	1.10.1070.11
Domain	PI3Kc	SMG1 ATR TRRAP	4.57e-04	16	181	3	SM00146
Domain	Myosin_head_motor_dom	MYO7B MYO9A MYO5C MYO3B	4.87e-04	38	181	4	IPR001609
Domain	MYOSIN_MOTOR	MYO7B MYO9A MYO5C MYO3B	4.87e-04	38	181	4	PS51456
Domain	Myosin_head	MYO7B MYO9A MYO5C MYO3B	4.87e-04	38	181	4	PF00063
Domain	MYSc	MYO7B MYO9A MYO5C MYO3B	4.87e-04	38	181	4	SM00242
Domain	SHR-BD	VPS13C VPS13D	5.53e-04	4	181	2	IPR009543
Domain	VPS13_C	VPS13C VPS13D	5.53e-04	4	181	2	PF16909
Domain	VPS13_C	VPS13C VPS13D	5.53e-04	4	181	2	IPR031645
Domain	SHR-BD	VPS13C VPS13D	5.53e-04	4	181	2	PF06650
Domain	P-loop_NTPase	ABCA2 ABCA4 MCM8 MYO7B LONP2 MYO9A ABCA13 NAIP MCM2 CHST1 SBNO2 MYO5C IQCA1 SBNO1 MYO3B ERCC6L2 NLRC5 DSEL HYDIN	5.95e-04	848	181	19	IPR027417
Domain	PI3_PI4_kinase	SMG1 ATR TRRAP	6.56e-04	18	181	3	PF00454
Domain	PI3_4_KINASE_1	SMG1 ATR TRRAP	6.56e-04	18	181	3	PS00915
Domain	PI3_4_KINASE_2	SMG1 ATR TRRAP	6.56e-04	18	181	3	PS00916
Domain	PI3/4_kinase_cat_dom	SMG1 ATR TRRAP	6.56e-04	18	181	3	IPR000403
Domain	PI3_4_KINASE_3	SMG1 ATR TRRAP	6.56e-04	18	181	3	PS50290
Domain	Groucho_enhance	TLE1 TLE3	9.16e-04	5	181	2	IPR009146
Domain	TLE_N	TLE1 TLE3	9.16e-04	5	181	2	PF03920
Domain	Groucho/TLE_N	TLE1 TLE3	9.16e-04	5	181	2	IPR005617
Domain	Vps5_C	SNX6 SNX5	9.16e-04	5	181	2	IPR015404
Domain	Vps5	SNX6 SNX5	9.16e-04	5	181	2	PF09325
Domain	FATC	SMG1 ATR	9.16e-04	5	181	2	PF02260
Domain	IQ	MYO7B MYO9A MYO5C IQCA1 MYO3B	1.14e-03	81	181	5	SM00015
Domain	SH3	DOCK2 RASA1 KALRN MYO7B ARHGEF38 DST RIMBP2 VAV1	1.24e-03	216	181	8	PS50002
Domain	PX	SNX6 SNX27 PLD2 SNX5	1.29e-03	49	181	4	PF00787
Domain	Sec23/24_helical_dom	SEC24A SEC24B	1.37e-03	6	181	2	IPR006900
Domain	-	DST PLEC	1.37e-03	6	181	2	3.90.1290.10
Domain	Sec23_24_beta_S	SEC24A SEC24B	1.37e-03	6	181	2	IPR012990
Domain	zf-Sec23_Sec24	SEC24A SEC24B	1.37e-03	6	181	2	PF04810
Domain	Sec23_trunk	SEC24A SEC24B	1.37e-03	6	181	2	PF04811
Domain	Sec23_helical	SEC24A SEC24B	1.37e-03	6	181	2	PF04815
Domain	PH_BEACH	LYST WDFY3	1.37e-03	6	181	2	PF14844
Domain	Sec23_BS	SEC24A SEC24B	1.37e-03	6	181	2	PF08033
Domain	FAT	ATR TRRAP	1.37e-03	6	181	2	PF02259
Domain	PIK-rel_kinase_FAT	ATR TRRAP	1.37e-03	6	181	2	IPR003151
Domain	Sec23/24_trunk_dom	SEC24A SEC24B	1.37e-03	6	181	2	IPR006896
Domain	Znf_Sec23_Sec24	SEC24A SEC24B	1.37e-03	6	181	2	IPR006895
Domain	NACHT	NLRX1 NAIP NLRC5	1.37e-03	23	181	3	PS50837
Domain	NACHT_NTPase	NLRX1 NAIP NLRC5	1.37e-03	23	181	3	IPR007111
Domain	Spectrin	KALRN SPTBN1 DST	1.37e-03	23	181	3	PF00435
Domain	ACTININ_2	SPTBN1 DST PLEC	1.37e-03	23	181	3	PS00020
Domain	ACTININ_1	SPTBN1 DST PLEC	1.37e-03	23	181	3	PS00019
Domain	Actinin_actin-bd_CS	SPTBN1 DST PLEC	1.37e-03	23	181	3	IPR001589
Domain	PX	SNX6 SNX27 PLD2 SNX5	1.39e-03	50	181	4	PS50195
Domain	SH3_domain	DOCK2 RASA1 KALRN MYO7B ARHGEF38 DST RIMBP2 VAV1	1.40e-03	220	181	8	IPR001452
Domain	-	SNX6 SNX27 PLD2 SNX5	1.49e-03	51	181	4	3.30.1520.10
Domain	-	RASA1 KALRN MYO7B SPTBN1 MTMR1 APBA3 PLEKHG1 MTMR6 PLCL2 PLD2 VAV1	1.55e-03	391	181	11	2.30.29.30
Domain	Phox	SNX6 SNX27 PLD2 SNX5	1.61e-03	52	181	4	IPR001683
Domain	IQ_motif_EF-hand-BS	MYO7B MYO9A MYO5C IQCA1 MYO3B	1.83e-03	90	181	5	IPR000048
Domain	Plectin	DST PLEC	1.90e-03	7	181	2	PF00681
Domain	Mob1_phocein	MOB3C MOB3B	1.90e-03	7	181	2	PF03637
Domain	Plectin_repeat	DST PLEC	1.90e-03	7	181	2	IPR001101
Domain	MOB_kinase_act_fam	MOB3C MOB3B	1.90e-03	7	181	2	IPR005301
Domain	-	MOB3C MOB3B	1.90e-03	7	181	2	1.20.140.30
Domain	Mob1_phocein	MOB3C MOB3B	1.90e-03	7	181	2	SM01388
Domain	PLEC	DST PLEC	1.90e-03	7	181	2	SM00250
Domain	IQ	MYO7B MYO9A MYO5C IQCA1 MYO3B	2.11e-03	93	181	5	PS50096
Domain	WD40_repeat_dom	LYST DMXL1 DNAI1 TBC1D31 TENM3 TLE1 TLE3 WDFY3 CFAP57	2.50e-03	297	181	9	IPR017986
Domain	-	ABCA2 ABCA4 MCM8 MYO7B LONP2 ABCA13 NAIP MCM2 CHST1 SBNO2 IQCA1 SBNO1 ERCC6L2 NLRC5 DSEL HYDIN	2.51e-03	746	181	16	3.40.50.300
Domain	Chorein_N	VPS13C VPS13D	2.52e-03	8	181	2	PF12624
Domain	MCM_OB	MCM8 MCM2	2.52e-03	8	181	2	PF17207
Domain	PH-BEACH_dom	LYST WDFY3	2.52e-03	8	181	2	IPR023362
Domain	VPS13_N	VPS13C VPS13D	2.52e-03	8	181	2	IPR026854
Domain	SSXRD	PRDM7 PRDM9	2.52e-03	8	181	2	PF09514
Domain	SSXRD_motif	PRDM7 PRDM9	2.52e-03	8	181	2	IPR019041
Domain	-	LYST WDFY3	2.52e-03	8	181	2	2.30.29.40
Domain	MCM_OB	MCM8 MCM2	2.52e-03	8	181	2	IPR033762
Domain	MCM_2	MCM8 MCM2	2.52e-03	8	181	2	PS50051
Domain	MCM_1	MCM8 MCM2	2.52e-03	8	181	2	PS00847
Domain	PH_BEACH	LYST WDFY3	2.52e-03	8	181	2	PS51783
Domain	AAA	ABCA2 ABCA4 MCM8 LONP2 ABCA13 NAIP	2.82e-03	144	181	6	SM00382
Domain	AAA+_ATPase	ABCA2 ABCA4 MCM8 LONP2 ABCA13 NAIP	2.82e-03	144	181	6	IPR003593
Domain	MCM	MCM8 MCM2	3.22e-03	9	181	2	SM00350
Domain	MCM_dom	MCM8 MCM2	3.22e-03	9	181	2	IPR001208
Domain	BEACH	LYST WDFY3	3.22e-03	9	181	2	PS50197
Domain	Beach	LYST WDFY3	3.22e-03	9	181	2	PF02138
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CA11 ABCA2 KALRN USP11 GNPTAB SPTBN1 CAPZA2 HLCS USP9Y PRPF8 ADD3 FOCAD DST SNX6 SBNO1 RALBP1 ZNF451 SIPA1L1 ASTN1 SPARCL1 UQCRC1 WDFY3 PLEC SNX5	1.12e-07	1285	186	24	35914814
Pubmed	Farnesyl diphosphate synthase exacerbates nonalcoholic steatohepatitis via the activation of AHR-CD36 axis.	FDPS CD36 AHR	1.51e-07	3	186	3	37310396
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	RPGRIP1L VPS13C SEC24A HLCS FAM83B PLEKHG1 NCOR1 MTMR6 ALDH1A2 ATP6V1H HOOK3 TBC1D31 SIPA1L1 SEC24B MINDY4 PLEC PCCA CLEC16A	8.70e-07	853	186	18	28718761
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SLC37A1 RNF130 MBTPS1 RASA1 MCM8 MYO9A TRIM26 VPS13C TOM1L1 NAIP ARHGEF38 TRRAP SLC25A37 SBNO2 ITFG1 IFRD1 TLE3 NLRC5 UQCRC1 CSMD1 ZSWIM4 PCCA ATP2B1 CLEC16A	1.55e-06	1489	186	24	28611215
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	SEL1L LARGE2 MBTPS1 ABCA2 ATR RPN2 MATN2 GNPTAB CD109 ZZEF1 HIF1AN DMXL1 ITFG1 MET SERPINI1 CSGALNACT2 TENM3 SNX6 DSEL ATP2B1 SNX5	2.09e-06	1201	186	21	35696571
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MBTPS1 RAPGEF5 FOCAD PLEKHG1 TENM3 TLE3 ZNF451 SIPA1L1 PLCL2 SNX27 RIMBP2 CLEC16A	2.25e-06	407	186	12	12693553
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	RPGRIP1L LONP2 CAPZA2 MCM2 PRPF8 HIF1AN RIF1 EXOC5 AP2S1 TIMM9 SBNO1 SIPA1L1 SEC24B EIF2B2 PLCL2 SNX27 MINDY4 UQCRC1 SNAPC1 PLEC ANKS3 RNF138	2.59e-06	1321	186	22	27173435
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	SMG1 HK2 KALRN USP11 SPTBN1 ARMCX2 NCOR1 HOOK3 DST SNX6 RALBP1 PLEC SNX5	3.14e-06	497	186	13	23414517
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	SEL1L ABCA4 RPGRIP1L MYO9A RPN2 USP11 SEC24A SPTBN1 CAPZA2 ARHGEF38 MAU2 MYRFL TRRAP PLEKHG1 DNAH17 EIF2B2 GMDS RIMBP2 CSMD1 RNF138 SNX5	3.53e-06	1242	186	21	30973865
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	ZBTB33 HK2 USP11 MTMR1 NR3C1 PRPF8 SKP2 TRRAP HIF1AN NCOR1 RIF1 IFRD1 TLE1 TLE3 UQCRC1 USF2 ATP2B1	4.05e-06	857	186	17	25609649
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ZBTB33 PUS3 RPGRIP1L VPS13C SEC24A ADD3 DMXL1 FAM83B MET NCOR1 RIF1 DST TENM3 SEC24B PCCA CLEC16A	4.93e-06	777	186	16	35844135
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	SEL1L RPN2 USP11 TRIM26 CD109 PPP2R3B MTMR1 MCM2 PRPF8 SERPINA1 MTMR6 ATP6V1H SNX6 SHCBP1 SNX27 PLD2 ATP2B1 SFN	5.53e-06	974	186	18	28675297
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ABCA2 KALRN NLRX1 RALGAPA2 ZZEF1 TRRAP LYST SBNO2 FOCAD PLEKHG1 NCOR1 MGAT1 AP2S1 DST KLHL36 NLRC5 ATG9A WDFY3 PLEC	8.36e-06	1105	186	19	35748872
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	UBR1 SMG1 HK2 ATR MCM8 LONP2 RPN2 NR3C1 ZZEF1 SBNO2 LPIN1 DST SHCBP1 CLEC16A	1.20e-05	650	186	14	38777146
Pubmed	A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.	HECW1 ALDH1A2 SPARCL1	1.23e-05	9	186	3	24121790
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	SMG1 ATR LONP2 RPN2 PRPF8 TERF2 TRRAP DST SIPA1L1 SHCBP1 SF3B5	1.45e-05	410	186	11	26949251
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RPGRIP1L RPN2 SEC24A SPTBN1 PPP2R3B MTMR1 TERF2 NCOR1 RIF1 MTMR6 TBC1D31 ZFYVE9 SNX6 TLE3 SEC24B PLCL2 SNX27 ATP2B1	1.50e-05	1049	186	18	27880917
Pubmed	Tel2 regulates the stability of PI3K-related protein kinases.	SMG1 ATR TRRAP	1.76e-05	10	186	3	18160036
Pubmed	Molecular genetics of successful smoking cessation: convergent genome-wide association study results.	CD109 ARHGEF38 SERPINA1 MOB3B ASTN1 CSMD1	1.79e-05	101	186	6	18519826
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	KALRN GNPTAB SPTBN1 DST SNX6 ZNF451 SPARCL1	1.80e-05	151	186	7	17043677
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	SEL1L MBTPS1 TCN1 RAPGEF5 GNPTAB SPTBN1 CD109 SBNO2 LPIN1 SERPINA1 MGAT1 DST FDPS TLE3 CD36 SHCBP1 ATG9A PLEC CSMD1 HYDIN	2.21e-05	1293	186	20	15342556
Pubmed	Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.	SMG1 ATR TRRAP	2.41e-05	11	186	3	20427287
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	DMXL1 FAM83B MTMR6 DST ZFYVE9 SNX6 SNX27 ATG9A WDFY3	2.50e-05	285	186	9	34369648
Pubmed	Cardiac myosin light chain is phosphorylated by Ca2+/calmodulin-dependent and -independent kinase activities.	MYLK3 MYLK4	2.84e-05	2	186	2	27325775
Pubmed	The NCoR Co-repressor Interacts with the Kaiso Transcription Factor through a Mechanism Different from That of BCL6 Interaction.	ZBTB33 NCOR1	2.84e-05	2	186	2	36786995
Pubmed	Hyperhomocysteinemia activates the aryl hydrocarbon receptor/CD36 pathway to promote hepatic steatosis in mice.	CD36 AHR	2.84e-05	2	186	2	26928949
Pubmed	An evidence for regulatory cross-talk between aryl hydrocarbon receptor and glucocorticoid receptor in HepG2 cells.	NR3C1 AHR	2.84e-05	2	186	2	17552871
Pubmed	N- and C-terminal domains in human holocarboxylase synthetase participate in substrate recognition.	HLCS PCCA	2.84e-05	2	186	2	19157941
Pubmed	Kaiso represses the expression of glucocorticoid receptor via a methylation-dependent mechanism and attenuates the anti-apoptotic activity of glucocorticoids in breast cancer cells.	ZBTB33 NR3C1	2.84e-05	2	186	2	26424557
Pubmed	Expression of the retinoic acid-metabolizing enzymes RALDH2 and CYP26b1 during mouse postnatal testis development.	CYP26B1 ALDH1A2	2.84e-05	2	186	2	18478160
Pubmed	Analysis of MTMR1 expression and correlation with muscle pathological features in juvenile/adult onset myotonic dystrophy type 1 (DM1) and in myotonic dystrophy type 2 (DM2).	MTMR1 DMPK	2.84e-05	2	186	2	20685272
Pubmed	A key enzyme in the biogenesis of lysosomes is a protease that regulates cholesterol metabolism.	MBTPS1 GNPTAB	2.84e-05	2	186	2	21719679
Pubmed	FIH-1-Mint3 axis does not control HIF-1 transcriptional activity in nucleus pulposus cells.	APBA3 HIF1AN	2.84e-05	2	186	2	24867948
Pubmed	A novel role for the dioxin receptor in fatty acid metabolism and hepatic steatosis.	CD36 AHR	2.84e-05	2	186	2	20303349
Pubmed	Study of Strawberry Notch homolog 1 and 2 expression in human glioblastoma.	SBNO2 SBNO1	2.84e-05	2	186	2	36695974
Pubmed	Transcriptional regulation of S phase kinase-associated protein 2 by NR4A orphan nuclear receptor NOR1 in vascular smooth muscle cells.	NR4A3 SKP2	2.84e-05	2	186	2	21868379
Pubmed	Groucho/TLE family proteins and transcriptional repression.	TLE1 TLE3	2.84e-05	2	186	2	10831834
Pubmed	Retinoic acid modulates retinaldehyde dehydrogenase 1 gene expression through the induction of GADD153-C/EBPbeta interaction.	ALDH1A2 AHR	2.84e-05	2	186	2	18992716
Pubmed	Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection.	SNX6 SNX5	2.84e-05	2	186	2	26118995
Pubmed	Crosstalk between activated forms of the aryl hydrocarbon receptor and glucocorticoid receptor.	NR3C1 AHR	2.84e-05	2	186	2	19463884
Pubmed	α1-Antitrypsin Binds to the Glucocorticoid Receptor with Anti-Inflammatory and Antimycobacterial Significance in Macrophages.	NR3C1 SERPINA1	2.84e-05	2	186	2	36162872
Pubmed	Differential functions of TLE1 and TLE3 depending on a specific phosphorylation site.	TLE1 TLE3	2.84e-05	2	186	2	33571907
Pubmed	Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.	SNX6 SNX5	2.84e-05	2	186	2	31576058
Pubmed	Ligand-induced repression of the glucocorticoid receptor gene is mediated by an NCoR1 repression complex formed by long-range chromatin interactions with intragenic glucocorticoid response elements.	NR3C1 NCOR1	2.84e-05	2	186	2	23428870
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	SEL1L ABCA2 RPN2 SPTBN1 CD109 ITFG1 MET	3.07e-05	164	186	7	32409323
Pubmed	Genomic strategy identifies a missense mutation in WD-repeat domain 65 (WDR65) in an individual with Van der Woude syndrome.	CFAP57 PAQR7 SFN	4.14e-05	13	186	3	21574244
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	UBR1 HK2 MYO9A USP11 SPTBN1 CAPZA2 MCM2 PRPF8 TRRAP RIF1 AP2S1 DST FDPS SHCBP1 SEC24B SNX27 UQCRC1 WDFY3 PLEC ATP2B1	4.17e-05	1353	186	20	29467282
Pubmed	Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.	MYO7B MYO9A MYO5C	5.25e-05	14	186	3	8022818
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MYO9A SEC24A SPTBN1 LYST FAM83B PLEKHG1 VPS13D IFRD1 DST MYLK3 SIPA1L1 SEC24B PLEC ATP2B1 SFN	6.69e-05	861	186	15	36931259
Pubmed	Combinatorial CRISPR screen identifies fitness effects of gene paralogues.	SMG1 ATR SEC24A SKP2 SLC25A37 MET SEC24B	6.81e-05	186	186	7	33637726
Pubmed	Docking motif-guided mapping of the interactome of protein phosphatase-1.	RPGRIP1L TMEM132D RIMBP2 CSMD1 HYDIN	7.20e-05	80	186	5	19389623
Pubmed	Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.	VPS13D CSMD1	8.50e-05	3	186	2	20610895
Pubmed	The meninges is a source of retinoic acid for the late-developing hindbrain.	CYP26B1 ALDH1A2	8.50e-05	3	186	2	12930800
Pubmed	BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin.	DST PLEC	8.50e-05	3	186	2	19932097
Pubmed	Profiling of enantiopure drugs towards aryl hydrocarbon (AhR), glucocorticoid (GR) and pregnane X (PXR) receptors in human reporter cell lines.	NR3C1 AHR	8.50e-05	3	186	2	24316275
Pubmed	A cellular factor stimulates ligand-dependent release of hsp90 from the basic helix-loop-helix dioxin receptor.	NR3C1 AHR	8.50e-05	3	186	2	8139547
Pubmed	Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia-mediated neurodegeneration.	TLR6 CD36	8.50e-05	3	186	2	28655763
Pubmed	Epithelial expression and chromosomal location of human TLE genes: implications for notch signaling and neoplasia.	TLE1 TLE3	8.50e-05	3	186	2	8808280
Pubmed	Dissociation of steroid receptor coactivator 1 and nuclear receptor corepressor recruitment to the human glucocorticoid receptor by modification of the ligand-receptor interface: the role of tyrosine 735.	NR3C1 NCOR1	8.50e-05	3	186	2	12569182
Pubmed	Vav protein guanine nucleotide exchange factor regulates CD36 protein-mediated macrophage foam cell formation via calcium and dynamin-dependent processes.	CD36 VAV1	8.50e-05	3	186	2	21865158
Pubmed	Activation of the GDNF-inducible transcription factor (GIF) gene promoter by glucocorticoid and progesterone.	NR3C1 GZF1	8.50e-05	3	186	2	19429458
Pubmed	Tle corepressors are differentially partitioned to instruct CD8+ T cell lineage choice and identity.	TLE1 TLE3	8.50e-05	3	186	2	30045946
Pubmed	TLE3 loss confers AR inhibitor resistance by facilitating GR-mediated human prostate cancer cell growth.	NR3C1 TLE3	8.50e-05	3	186	2	31855178
Pubmed	Holocarboxylase synthetase interacts physically with nuclear receptor co-repressor, histone deacetylase 1 and a novel splicing variant of histone deacetylase 1 to repress repeats.	HLCS NCOR1	8.50e-05	3	186	2	24840043
Pubmed	Myotonic dystrophy protein kinase (DMPK) prevents ROS-induced cell death by assembling a hexokinase II-Src complex on the mitochondrial surface.	HK2 DMPK	8.50e-05	3	186	2	24136222
Pubmed	Protein 14-3-3sigma interacts with and favors cytoplasmic subcellular localization of the glucocorticoid receptor, acting as a negative regulator of the glucocorticoid signaling pathway.	NR3C1 SFN	8.50e-05	3	186	2	12730237
Pubmed	Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors.	NR3C1 NCOR1	8.50e-05	3	186	2	15016838
Pubmed	Oxidized LDL/CD36 interaction induces loss of cell polarity and inhibits macrophage locomotion.	CD36 VAV1	8.50e-05	3	186	2	22718904
Pubmed	Control of energy balance by hypothalamic gene circuitry involving two nuclear receptors, neuron-derived orphan receptor 1 and glucocorticoid receptor.	NR4A3 NR3C1	8.50e-05	3	186	2	23897430
Pubmed	Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis.	CYP26B1 ALDH1A2	8.50e-05	3	186	2	11744378
Pubmed	A loss-of-function screen reveals SNX5 and SNX6 as potential components of the mammalian retromer.	SNX6 SNX5	8.50e-05	3	186	2	17148574
Pubmed	RU486-induced glucocorticoid receptor agonism is controlled by the receptor N terminus and by corepressor binding.	NR3C1 NCOR1	8.50e-05	3	186	2	12011091
Pubmed	The ATM-related kinase, hSMG-1, bridges genome and RNA surveillance pathways.	SMG1 ATR	8.50e-05	3	186	2	15279777
Pubmed	AhR activation promotes Treg cell generation by enhancing Lkb1-mediated fatty acid oxidation via the Skp2/K63-ubiquitination pathway.	SKP2 AHR	8.50e-05	3	186	2	36930164
Pubmed	A non-metabolic function of hexokinase 2 in small cell lung cancer: promotes cancer cell stemness by increasing USP11-mediated CD133 stability.	HK2 USP11	8.50e-05	3	186	2	35975322
Pubmed	Human transcription factor protein interaction networks.	SMG1 ZBTB33 RPN2 USP11 SEC24A SPTBN1 TRRAP MYO5C NCOR1 RIF1 TIMM9 DST TTC31 TLE1 TLE3 ZNF451 SEC24B UQCRC1 PCCA SFN	8.80e-05	1429	186	20	35140242
Pubmed	Functional proteomics mapping of a human signaling pathway.	SMG1 SPTBN1 ZZEF1 NCOR1 MGAT1 DST ZFYVE9 TENM3 ZNF451 PLCL2 SPARCL1 PLEC	8.89e-05	591	186	12	15231748
Pubmed	Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome.	SEL1L UBR1 RPN2 ZZEF1 ATP2B1	9.09e-05	84	186	5	31616248
Pubmed	A large family of endosome-localized proteins related to sorting nexin 1.	SNX6 SNX27 SNX5	9.68e-05	17	186	3	11485546
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	MTMR1 MCM2 RALGAPA2 ADD3 FAM83B MET DST ZFYVE9 TENM3 ATP2B1	9.80e-05	421	186	10	36976175
Pubmed	A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins.	MYO7B CAPZA2 ADD3 PLEC	9.94e-05	45	186	4	22114352
Pubmed	Genomic analysis of mouse retinal development.	ABCA2 VASH1 BTBD17 MAU2 SKP2 SLC25A37 NCOR1 MGAT1 SERPINI1 DST SPARCL1 WDFY3 PLEC USF2 PCCA ANKS3	1.10e-04	1006	186	16	15226823
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	UBA5 HK2 USP11 SEC24A SPTBN1 TOM1L1 CAPZA2 MCM2 NR3C1 ZZEF1 ATP6V1H SNX6 SBNO1 FDPS TLE3 EIF2B2 GMDS PLEC SFN SNX5	1.12e-04	1455	186	20	22863883
Pubmed	Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism.	ATR USP11 MCM2	1.16e-04	18	186	3	28191891
Pubmed	Groucho co-repressor proteins regulate β cell development and proliferation by repressing Foxa1 in the developing mouse pancreas.	SERPINA1 TLE1 TLE3	1.16e-04	18	186	3	33658226
Pubmed	Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease.	PLEKHG1 TENM3 CSMD1	1.16e-04	18	186	3	24058526
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	LONP2 MYO9A VPS13C CAPZA2 BTBD17 GRIA3 ADD3 AP2S1 SIPA1L1 ATP2B1	1.17e-04	430	186	10	32581705
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	DOCK2 ZBTB33 LONP2 MYO9A RPN2 CAPZA2 PPP2R3B MCM2 PLEKHG1 RIF1 RALBP1 SHCBP1 PLEC VAV1 SF3B5	1.32e-04	916	186	15	32203420
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	RPGRIP1L SPTBN1 CAPZA2 PRPF8 MYO5C FAM83B RIF1 PLEC SF3B5	1.53e-04	361	186	9	30344098
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	MIER2 NCOR1 RIF1 VPS13D GZF1 TENM3 RALBP1 SIPA1L1 WDFY3 ATP2B1 SNX5	1.60e-04	536	186	11	15840001
Pubmed	Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice.	SPTBN1 CAPZA2 ADD3	1.60e-04	20	186	3	18723693
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	MIER2 NCOR1 RIF1 VPS13D GZF1 TENM3 RALBP1 SIPA1L1 WDFY3 ATP2B1 SNX5	1.65e-04	538	186	11	10512203
Pubmed	TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination.	TLE1 TLE3	1.69e-04	4	186	2	8645603
Pubmed	NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells.	APBA3 HIF1AN	1.69e-04	4	186	2	26948053
Pubmed	A mouse homologue of Strawberry Notch is transcriptionally regulated by Reelin signal.	SBNO2 SBNO1	1.69e-04	4	186	2	17045962
Pubmed	Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2.	TLR6 CD36	1.69e-04	4	186	2	19847289
Pubmed	Two distinct regions of the CD28 intracytoplasmic domain are involved in the tyrosine phosphorylation of Vav and GTPase activating protein-associated p62 protein.	RASA1 VAV1	1.69e-04	4	186	2	9620604
Pubmed	Reversal of DDK-Mediated MCM Phosphorylation by Rif1-PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/Chk1.	ATR RIF1	1.69e-04	4	186	2	28273463
Pubmed	Transcriptional factor aryl hydrocarbon receptor (Ahr) controls cardiovascular and respiratory functions by regulating the expression of the Vav3 proto-oncogene.	AHR VAV1	1.69e-04	4	186	2	21115475
Pubmed	Genetic variations in ATP2B1, CSK, ARSG and CSMD1 loci are related to blood pressure and/or hypertension in two Korean cohorts.	CSMD1 ATP2B1	1.69e-04	4	186	2	19960030
Interaction	ABCA4 interactions	ABCA4 RPN2 ABCA13 NR3C1	4.58e-07	8	184	4	int:ABCA4
Interaction	DSCAM interactions	KALRN USP11 GNPTAB SPTBN1 PRPF8 DST SIPA1L1 ASTN1 UQCRC1 PLEC	3.99e-06	171	184	10	int:DSCAM
Interaction	GARNL3 interactions	GARNL3 RAPGEF5 RALGAPA2 SIPA1L1	6.27e-06	14	184	4	int:GARNL3
Interaction	HSP90B1 interactions	SEL1L UBA5 SMG1 RNF130 RPN2 VPS13C SPTBN1 MCM2 NR3C1 RALGAPA2 TERF2 TRRAP ITFG1 LPIN1 RIF1 DNAH17 MYLK4 UQCRC1 SFN	8.35e-06	650	184	19	int:HSP90B1
Interaction	PLEC interactions	ATR MYO9A RAPGEF5 CAPZA2 MCM2 PRPF8 HOOK3 DST ZNF451 SEC24B UQCRC1 PLEC VAV1 RNF138 SFN	1.01e-05	430	184	15	int:PLEC
Interaction	RAB11A interactions	RNF130 ATR USP11 VPS13C SPTBN1 NR3C1 RALGAPA2 ADD3 DMXL1 MYO5C FAM83B EXOC5 MTMR6 DST ZFYVE9 SNX6 SEC24B WDFY3 ATP2B1 CLEC16A SNX5	2.42e-05	830	184	21	int:RAB11A
Interaction	SIPA1L2 interactions	UBR1 RPGRIP1L GARNL3 RALGAPA2 SIPA1L1 CLEC16A SFN SNX5	3.61e-05	136	184	8	int:SIPA1L2
Interaction	HYOU1 interactions	SEL1L LARGE2 RNF130 HK2 RPN2 CD109 MCM2 NR3C1 MET HOOK3 TENM3 SNX5	3.65e-05	317	184	12	int:HYOU1
Interaction	GPR156 interactions	PPP2R3B PRPF8 ZZEF1 SNX27 PLD2 RNF138	4.67e-05	71	184	6	int:GPR156
Interaction	AGMAT interactions	UBR1 FDPS SNX27 MINDY4 SF3B5	5.46e-05	45	184	5	int:AGMAT
GeneFamily	ATP binding cassette subfamily A	ABCA2 ABCA4 ABCA13	1.19e-04	14	128	3	805
GeneFamily	WD repeat domain containing	LYST DMXL1 DNAI1 TBC1D31 TLE1 TLE3 WDFY3 CFAP57	5.59e-04	262	128	8	362
GeneFamily	NLR family	NLRX1 NAIP NLRC5	7.11e-04	25	128	3	666
GeneFamily	MOB kinase activators\|STRIPAK complex	MOB3C MOB3B	1.02e-03	7	128	2	647
GeneFamily	Sorting nexins\|PX-BAR domain containing	SNX6 SNX27 SNX5	1.11e-03	29	128	3	754
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	KALRN ARHGEF38 PLEKHG1 VAV1	1.23e-03	66	128	4	722
GeneFamily	EF-hand domain containing\|Plakins	DST PLEC	1.35e-03	8	128	2	939
GeneFamily	MCM family	MCM8 MCM2	1.73e-03	9	128	2	1085
GeneFamily	WD repeat domain containing\|BEACH domain containing	LYST WDFY3	1.73e-03	9	128	2	1230
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	RPGRIP1L NCOR1 TMEM132D RIMBP2 CSMD1 HYDIN	1.83e-03	181	128	6	694
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RPGRIP1L HECW1 CAPN6	2.09e-03	36	128	3	823
GeneFamily	Sorting nexins\|PX-BAR domain containing	SNX6 SNX5	3.13e-03	12	128	2	1290
GeneFamily	Myotubularins\|Phosphoinositide phosphatases	MTMR1 MTMR6	4.92e-03	15	128	2	903
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	MIER2 TERF2 NCOR1	6.27e-03	53	128	3	532
GeneFamily	Dyneins, axonemal	DNAI1 DNAH17	6.31e-03	17	128	2	536
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM7 PRDM9	6.31e-03	17	128	2	1197
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	SMG1 RPGRIP1L TRIM26 VPS13C RALGAPA2 PRPF8 NCOR1 RIF1 SBNO1 SIPA1L1	6.20e-07	180	184	10	M8239
Coexpression	NAKAYA_MONOCYTE_FLUMIST_AGE_18_50YO_7DY_UP	SMG1 ATR SEC24A GNPTAB NAIP NR4A3 MAU2 TLR6 TRRAP LYST DMXL1 NCOR1 EXOC5 IFRD1 NUDT15	1.54e-06	477	184	15	M40930
Coexpression	GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN	MBTPS1 ABCA4 RASA1 MYO9A VPS13C NR3C1 RALGAPA2 LYST SLC25A37 SIPA1L1	1.54e-06	199	184	10	M9236
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	ATR RASA1 SEC24A NR3C1 ZZEF1 TRRAP RIF1 IFRD1 ATP6V1H DST TBC1D31 ZFYVE9 TLE1 ZNF451 SIPA1L1 SEC24B WDFY3 PCCA ATP2B1 CLEC16A	2.76e-06	856	184	20	M4500
Coexpression	GSE20727_CTRL_VS_H2O2_TREATED_DC_DN	DOCK2 RNF130 MYO9A TERF2 LYST SLC25A37 ADD3 KLHL36 ATP2B1	1.08e-05	196	184	9	M9243
Coexpression	GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_UP	DOCK2 SMG1 RNF130 RASA1 VPS13C ATP6V1H KLHL36 SIPA1L1 SNX27	1.22e-05	199	184	9	M9238
Coexpression	STOSSI_RESPONSE_TO_ESTRADIOL	TCN1 NR4A3 ACOX2 TLE3 SPARCL1	1.75e-05	46	184	5	M11695
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	CA11 SMG1 PUS3 MATN2 SPTBN1 CAPN6 GRIA3 MAU2 NR3C1 SLC25A37 ADD3 DMXL1 RIF1 VPS13D ALDH1A2 TLE3 ZNF451 SNX27 WDFY3 PLEC ATP2B1	4.45e-06	790	182	21	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_1000	SMG1 PUS3 SPTBN1 GRIA3 SERPINA1 ALDH1A2 ZNF451 SNX27 WDFY3 PLEC ATP2B1	1.53e-05	259	182	11	gudmap_developingGonad_e12.5_epididymis_k3_1000
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 MYO9A ABCA13 LPIN1 MET ALDH1A2 TMEM132D DNAH17 GMDS WDFY3 HYDIN	3.43e-10	183	186	11	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC37A1 RNF130 TCN1 RAPGEF5 TOM1L1 ARHGEF38 HLCS RALGAPA2 SLC25A37 MYO5C GMDS	8.82e-10	200	186	11	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ABCA13 LPIN1 MET ALDH1A2 TMEM132D GMDS WDFY3 HYDIN	8.13e-08	183	186	9	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ABCA13 ARHGEF38 MYRFL MET ALDH1A2 MYO3B RIMBP2 HYDIN	1.12e-07	190	186	9	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CD109 NAIP LYST SLC25A37 MET SERPINA1 CD36 AHR WDFY3	1.59e-07	198	186	9	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	RAPGEF5 SPTBN1 VASH1 RALGAPA2 ADD3 DST CD36 AHR SPARCL1	1.73e-07	200	186	9	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	mild-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RNF130 NAIP LYST MEFV SERPINA1 CD36 AHR WDFY3 PLEC	1.73e-07	200	186	9	934c2efc780318c66d667ca75be0de350361d351
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF38 LYST MYO5C FAM83B MET DST MYO3B RIMBP2	4.21e-07	162	186	8	373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ABCA13 ALDH1A2 TMEM132D DNAH17 GMDS WDFY3 HYDIN	7.89e-07	176	186	8	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	SEL1L SMG1 MBTPS1 KALRN GNPTAB LYST LPIN1 DST	7.89e-07	176	186	8	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ABCA13 LPIN1 ALDH1A2 TMEM132D DNAH17 GMDS HYDIN	8.23e-07	177	186	8	da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KALRN RAPGEF5 SPTBN1 PKD1L3 ADD3 PLEKHG1 DST CD36	8.59e-07	178	186	8	ad3de3e03a401dac64431a541899445262246347
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	DOCK2 VASH1 NAIP CHST1 TLR6 MEFV TENM3 IQCA1	8.96e-07	179	186	8	cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ABCA13 LPIN1 ALDH1A2 TMEM132D GMDS WDFY3 HYDIN	9.74e-07	181	186	8	071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF38 LYST MYO5C FAM83B MET DST MYO3B RIMBP2	1.02e-06	182	186	8	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP26B1 VASH1 DNAI1 SERPINI1 MYLK4 PCDHGB4 ASTN1 HYDIN	1.10e-06	184	186	8	1c857126c0ea0671f0d60b048efca288d348d653
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LYST MYO5C FAM83B MET DST MYO3B RIMBP2 PCCA	1.24e-06	187	186	8	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RAPGEF5 ARHGEF38 MYO5C PLEKHG1 MET TMEM132D MYO3B RIMBP2	1.35e-06	189	186	8	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	COVID-19-Heart-EC_3\|Heart / Disease (COVID-19 only), tissue and cell type	KALRN RAPGEF5 CD109 RALGAPA2 LYST MYO5C PLEKHG1 GMDS	1.40e-06	190	186	8	78e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LARGE2 RAPGEF5 ARHGEF38 MYO5C PLEKHG1 MET TMEM132D RIMBP2	1.52e-06	192	186	8	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	MYO9A ARHGEF38 MYO5C FAM83B MET DST MYO3B RIMBP2	1.77e-06	196	186	8	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-OPC_related\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	LONP2 CAPN6 MCM2 DNAI1 SLC9A2 TMEM132D MOB3B	1.80e-06	137	186	7	264d5e06c37d1a9ef7748091b67d2a5aa803096e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-OPC_related-Oligodendrocyte/OPC\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	LONP2 CAPN6 MCM2 DNAI1 SLC9A2 TMEM132D MOB3B	1.80e-06	137	186	7	8ce463d1d74ac0ce80b812217d6bd76a788f14d2
ToppCell	distal-3-Endothelial-Bronchial_Vessel_2\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP26B1 GARNL3 LONP2 RAPGEF5 MYO5C PLEKHG1 TLE1 SPARCL1	1.91e-06	198	186	8	f701d06e3d7fd2192afae3698c5ec3c355e96da3
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 MYO9A ABCA13 ARHGEF38 MET SERPINA1 GMDS SFN	1.98e-06	199	186	8	2e7f517c0444b4f29ff11c26ab32e9cc0f7e99ef
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	RAPGEF5 SPTBN1 CD109 VASH1 ADD3 DST CD36 SPARCL1	2.06e-06	200	186	8	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	severe-Classical_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RNF130 NAIP SLC25A37 SERPINA1 TLE3 CD36 AHR ATP2B1	2.06e-06	200	186	8	f46689940fdea500ce2457eec412dd2c46705819
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	RAPGEF5 CD109 VASH1 ADD3 DST CD36 AHR SPARCL1	2.06e-06	200	186	8	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	control-HLA-DR-_S100A+_Monocyte\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RNF130 HK2 NAIP LYST MEFV CD36 SNX27 WDFY3	2.06e-06	200	186	8	9e3e13a68bc1110fa000ec2d80f4c654ddbce17e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IP6K3 MYO9A ABCA13 USP9Y ALDH1A2 TMEM132D CBLN2	2.40e-06	143	186	7	7a7a9829ba63468c9745904d9e993590051207ab
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACOX2 DNAI1 MYLK3 IQCA1 IZUMO1 CFAP57 SFN	5.93e-06	164	186	7	d9531848105d606adedde65426177cf851140e31
ToppCell	facs-Lung-Endomucin-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PUS3 HK2 ABCA13 NLRX1 LPIN1 SHCBP1 DNAH17	6.42e-06	166	186	7	a2ce44702a0cd5fa5872cac3302d3c451205feef
ToppCell	facs-Lung-Endomucin-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PUS3 HK2 ABCA13 NLRX1 LPIN1 SHCBP1 DNAH17	6.42e-06	166	186	7	0f641302a6b71c4badaaf20f51162bfc2386b167
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEL1L HK2 MYO9A MYO5C IFRD1 ALDH1A2 IZUMO1	8.42e-06	173	186	7	c62e3ffed55bbb00dcaef6da0aab8446f3f55085
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEL1L HK2 MYO9A MYO5C IFRD1 ALDH1A2 IZUMO1	8.42e-06	173	186	7	f612d4ea9ab8dcde475f4118bca3e49be786e7fa
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	KALRN MATN2 MTMR1 ARMCX2 SHCBP1 ZSWIM4 CLEC16A	8.42e-06	173	186	7	090dc3c5bd2652a65c2490fc889da858c3af368f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HK2 VASH1 DNAJC22 SERPINA1 CD36 GMDS ANKS3	9.07e-06	175	186	7	5a29323d4a848ea544cdd78a0a4b73f9c122dc5e
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	SMG1 MBTPS1 KALRN GNPTAB LYST LPIN1 DST	9.77e-06	177	186	7	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC22A25 ABCA4 CYP26B1 PTCHD4 PLEKHG1 MET SPARCL1	1.01e-05	178	186	7	f7f88879a05b2b5fa92cf5317b76f7a3064d1358
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MCM8 TCN1 MCM2 ACOX2 SERPINA1 CD36 SHCBP1	1.05e-05	179	186	7	e1bfd553c043ebc070ccf8545d489ba16d9b2ef4
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-5\|TCGA-Colorectal / Sample_Type by Project: Shred V9	SLC37A1 DNAJC22 MYO5C LPIN1 SLC9A2 RALBP1 GMDS	1.13e-05	181	186	7	8fcc9e77fee7c248df26b6c59b10e672242e2084
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN VASH1 ADD3 PLEKHG1 HOOK3 SPARCL1 MINDY4	1.13e-05	181	186	7	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEL1L CA11 BTBD17 CHST1 ALDH1A2 SERPINI1 IZUMO1	1.13e-05	181	186	7	97022416d0f5a5ba9c9bd5e70ce95cf4cb19af89
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 ALDH1A2 IQCA1 TMEM132D GMDS WDFY3 HYDIN	1.17e-05	182	186	7	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC22A25 ABCA4 CYP26B1 PTCHD4 PLEKHG1 MET SPARCL1	1.21e-05	183	186	7	b5d041d0a3506c33de72bf14fa0443f4410fddf1
ToppCell	LV-07._Pericyte\|World / Chamber and Cluster_Paper	KALRN RAPGEF5 VPS13D TLE1 CD36 ASTN1 SPARCL1	1.21e-05	183	186	7	273db6a3b00a93ca852498471187b642b5368185
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC22A25 ABCA4 CYP26B1 PTCHD4 PLEKHG1 MET SPARCL1	1.21e-05	183	186	7	274076a0978bce2bd53a1732045f18ef0f2d9985
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KALRN RAPGEF5 CD109 RALGAPA2 PLEKHG1 CD36 SPARCL1	1.21e-05	183	186	7	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 HECW1 KALRN MYO7B ABCA13 CSMD1 HYDIN	1.26e-05	184	186	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	COPD-Myeloid-cMonocyte\|World / Disease state, Lineage and Cell class	NAIP SLC25A37 MEFV ALDH1A2 SIPA1L1 CSMD1 ATP2B1	1.26e-05	184	186	7	ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 HECW1 KALRN MYO7B ABCA13 CSMD1 HYDIN	1.26e-05	184	186	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 HECW1 KALRN MYO7B ABCA13 CSMD1 HYDIN	1.26e-05	184	186	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA13 RAPGEF5 ARHGEF38 MYO5C MET AHR CLEC16A	1.35e-05	186	186	7	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KALRN RAPGEF5 SPTBN1 PKD1L3 ADD3 PLEKHG1 CD36	1.35e-05	186	186	7	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF38 MYO5C FAM83B MET DST MYO3B RIMBP2	1.40e-05	187	186	7	87b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF38 MYO5C FAM83B MET DST MYO3B RIMBP2	1.40e-05	187	186	7	42a1267bfc27b4460b8409ada580a87c4385841c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF38 MYO5C FAM83B MET DST MYO3B RIMBP2	1.40e-05	187	186	7	64afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell	Control-Endothelial_cells-Endothelial_cells_(general)\|Control / group, cell type (main and fine annotations)	SLC22A25 SPTBN1 CD109 RALGAPA2 PTCHD4 PLEKHG1 CD36	1.40e-05	187	186	7	fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 MYO9A ABCA13 MYRFL MET SERPINA1 DNAH17	1.40e-05	187	186	7	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC22A25 HECW1 KALRN RAPGEF5 MYO5C MET IQCA1	1.44e-05	188	186	7	50c1b1d690f0e9443082f2adf4f1b8e9ce4cd337
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ABCA13 MET ALDH1A2 TMEM132D GMDS HYDIN	1.44e-05	188	186	7	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	COPD-Myeloid-cMonocyte\|COPD / Disease state, Lineage and Cell class	NAIP SLC25A37 MEFV ALDH1A2 CSGALNACT2 SIPA1L1 ATP2B1	1.49e-05	189	186	7	d29f3a0bd23e6eb46389e6eb7ef21851c7b57545
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ABCA13 ALDH1A2 TMEM132D GMDS WDFY3 HYDIN	1.49e-05	189	186	7	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NAIP SLC25A37 MEFV SERPINA1 CSGALNACT2 CD36 AHR	1.49e-05	189	186	7	55aba1ebc012006a5db3ff9c92589cb3d9f7c68a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ARHGEF38 FAM83B MET TLE1 MYO3B RIMBP2	1.55e-05	190	186	7	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	LARGE2 ARHGEF38 MYO5C PLEKHG1 TMEM132D MYO3B RIMBP2	1.55e-05	190	186	7	c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ARHGEF38 FAM83B MET TLE1 MYO3B RIMBP2	1.55e-05	190	186	7	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASA1 SPTBN1 ADD3 HOOK3 DST AHR ATP2B1	1.55e-05	190	186	7	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ABCA13 MET ALDH1A2 TMEM132D GMDS HYDIN	1.60e-05	191	186	7	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ARHGEF38 FAM83B MET ALDH1A2 MYO3B RIMBP2	1.60e-05	191	186	7	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NAIP SLC25A37 MEFV SERPINA1 CSGALNACT2 CD36 AHR	1.60e-05	191	186	7	63d4226a8b59f648bdc9f41e4b2d750dfa342034
ToppCell	COVID-19-lung-Secretory\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TCN1 ARHGEF38 MYO5C MET FAT2 AHR SFN	1.65e-05	192	186	7	59261098ccb52306f837f632ebaea45b90ad30fe
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	RAPGEF5 RALGAPA2 PLEKHG1 ALDH1A2 TLE1 GMDS SPARCL1	1.71e-05	193	186	7	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ARHGEF38 MET ALDH1A2 MYO3B RIMBP2 CLEC16A	1.71e-05	193	186	7	263d185af6ed80e639f864e4966268e0862c61dc
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HK2 CD109 SLC25A37 CSGALNACT2 CD36 SNAPC1 ATP2B1	1.71e-05	193	186	7	b93f6af5999ad207fef5edc2bd900c7c6342f626
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ARHGEF38 MET ALDH1A2 MYO3B RIMBP2 CLEC16A	1.71e-05	193	186	7	80e058c224749b5fe0ba3e944b48317c2371cb63
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A ARHGEF38 MET ALDH1A2 MYO3B RIMBP2 CLEC16A	1.71e-05	193	186	7	b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	RAPGEF5 SPTBN1 RALGAPA2 PLEKHG1 ALDH1A2 TLE1 GMDS	1.71e-05	193	186	7	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MYO7B VPS13C LYST DMXL1 PLEKHG1 MOB3B ATP2B1	1.77e-05	194	186	7	ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DOCK2 HK2 CD109 SERPINA1 MGAT1 TLE3 SNAPC1	1.83e-05	195	186	7	d53585715c7f5827c4f5a6db11cb31857ee9d4f0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 VASH1 NR4A3 MGAT1 SIPA1L1 MOB3B VAV1	1.83e-05	195	186	7	62dc745e1aa3e2e58afa16c7bb2cf9b03d4e8105
ToppCell	CF-Myeloid\|CF / Disease state, Lineage and Cell class	RNF130 RALGAPA2 SLC25A37 SERPINA1 ALDH1A2 CSGALNACT2 ATP2B1	1.83e-05	195	186	7	ecf604de496f389a49429d0bb211e1db6019cc8b
ToppCell	Control-Myeloid\|Control / Disease state, Lineage and Cell class	RNF130 SERPINA1 MGAT1 AP2S1 SIPA1L1 MOB3B ATP2B1	1.83e-05	195	186	7	46ce2e403ca5d757e5ba17349b6c7ce5cde1f195
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HECW1 KALRN GRIA3 FOCAD RIMBP2 CSMD1 ATP2B1	1.89e-05	196	186	7	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RNF130 MGAT1 AP2S1 HOOK3 CD36 AHR PLEC	1.89e-05	196	186	7	28e9e191361966df3a9bd48450090577aa72a999
ToppCell	10x5'-Lung-Myeloid_Mac-Intermediate_macrophages\|Lung / Manually curated celltypes from each tissue	RNF130 HK2 NR4A3 SLC25A37 MGAT1 AP2S1 CD36	1.89e-05	196	186	7	fede2c605f7581ce2ea7a284cffffa1a3970d811
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MIER2 KALRN RAPGEF5 SPTBN1 PLEKHG1 TLE1 SPARCL1	1.95e-05	197	186	7	86591849476b3925857a82b6913f65e74df200c1
ToppCell	distal-Endothelial-Bronchial_Vessel_2-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP26B1 GARNL3 LONP2 RAPGEF5 MYO5C LPIN1 SPARCL1	1.95e-05	197	186	7	9fcfbfbe78e8fe90c76eb37a58ed9dc8ece652a1
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOCK2 LYST SLC25A37 SERPINA1 IFRD1 TLE3 ATP2B1	1.95e-05	197	186	7	3cd1c816bc7a57278b2ef615b69545356ab8f522
ToppCell	COVID-19_Severe-Classical_Monocyte\|World / disease group, cell group and cell class	RNF130 NAIP SLC25A37 SERPINA1 CD36 AHR WDFY3	1.95e-05	197	186	7	344801997b89bd81d8d5c3c872934de523233a8d
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NAIP LYST SLC25A37 SERPINA1 CD36 AHR WDFY3	2.02e-05	198	186	7	a77f3440d7fb6a50066abc7e9ad59e83798ef13d
ToppCell	356C-Myeloid-Monocyte-CD14+_Monocyte\|356C / Donor, Lineage, Cell class and subclass (all cells)	RNF130 NR4A3 SLC25A37 SERPINA1 MGAT1 CD36 ATP2B1	2.02e-05	198	186	7	8f53df66712c0b4a176098c0dbb3c2c13d3f56df
ToppCell	systemic_lupus_erythematosus-flare-Myeloid\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RNF130 CAPZA2 NAIP LYST SERPINA1 AP2S1 CD36	2.02e-05	198	186	7	189346c5eb715f3be427bec3b8e067ababb5b475
ToppCell	(3)_Monocyte\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	RNF130 NR4A3 SLC25A37 SERPINA1 MGAT1 CD36 ATP2B1	2.02e-05	198	186	7	dff753c3d6919ea9f504bdc9859ed542a5490a9d
ToppCell	facs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARGE2 SMG1 MBTPS1 MATN2 CD109 DST PLEC	2.02e-05	198	186	7	22559b161e67b49fe8028bfaf861e069063599f5
ToppCell	Adult-Immune\|Adult / Lineage, Cell type, age group and donor	DOCK2 RNF130 MGAT1 PLCL2 MOB3B ATP2B1 VAV1	2.02e-05	198	186	7	9bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCell	COVID-19-lung-Capillary_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RAPGEF5 SPTBN1 CD109 RALGAPA2 PLEKHG1 SPARCL1 CSMD1	2.02e-05	198	186	7	45419f2804b4be79bae6632e71c54e1af482d115
ToppCell	356C-Myeloid-Monocyte\|356C / Donor, Lineage, Cell class and subclass (all cells)	RNF130 NR4A3 SLC25A37 SERPINA1 MGAT1 CD36 ATP2B1	2.02e-05	198	186	7	ad5b9a92f3ad7f4220f173cee4dba0977bd803fe
ToppCell	COVID-19-lung-Capillary_2\|lung / Disease (COVID-19 only), tissue and cell type	RAPGEF5 SPTBN1 CD109 RALGAPA2 PLEKHG1 SPARCL1 CSMD1	2.08e-05	199	186	7	793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCell	cellseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MIER2 KALRN RAPGEF5 SPTBN1 PLEKHG1 TLE1 SPARCL1	2.08e-05	199	186	7	9364199c5b4540ce2e14341fd9d504b695f8249d
Drug	Esculin Hydrate [531-75-9]; Up 200; 11.8uM; PC3; HT_HG-U133A	SEL1L SLC37A1 RAPGEF5 SPTBN1 HLCS SKP2 SBNO2 VPS13D KLHL36 PLCL2 GMDS USF2	7.49e-08	197	184	12	6310_UP
Drug	Flurandrenolide [1524-88-5]; Down 200; 9.2uM; PC3; HT_HG-U133A	SEL1L MBTPS1 ABCA2 HLCS SBNO2 LPIN1 MET EXOC5 TENM3 DMPK PCCA	6.02e-07	196	184	11	3679_DN
Drug	Atracurium besylate [64228-81-5]; Down 200; 3.2uM; PC3; HT_HG-U133A	SEL1L MBTPS1 SKP2 SLC25A37 MET EXOC5 SERPINA1 VPS13D AP2S1 TLE3 PLEC	6.66e-07	198	184	11	1824_DN
Drug	DAPH; Down 200; 10uM; MCF7; HG-U133A	SPTBN1 MAU2 HIF1AN ADD3 LPIN1 VPS13D IFRD1 RALBP1 ATP2B1 CLEC16A	4.86e-06	197	184	10	624_DN
Drug	1-Naphthylamine	FAM83B TMEM132D AHR	1.02e-05	6	184	3	ctd:D015057
Drug	GP-7,3	RNF130 ABCA2 TMEM132D CD36	1.81e-05	20	184	4	CID000164207
Drug	Nitrofural [59-87-0]; Down 200; 20.2uM; PC3; HT_HG-U133A	SLC37A1 MBTPS1 TCN1 MTMR1 SKP2 TRRAP MET EXOC5 PLEC	2.64e-05	191	184	9	6721_DN
Drug	Atropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; HL60; HG-U133A	UBA5 HECW1 TOM1L1 DMXL1 MTMR6 RALBP1 SNX27 ATG9A WDFY3	2.86e-05	193	184	9	1768_DN
Drug	phentolamine; Up 200; 11.5uM; MCF7; HT_HG-U133A_EA	SEL1L SLC37A1 SPTBN1 LPIN1 MGAT1 SIPA1L1 AHR ATP2B1 CLEC16A	2.98e-05	194	184	9	1138_UP
Drug	Verapamyl hydrochloride [152-11-4]; Up 200; 8.2uM; PC3; HG-U133A	SEL1L SLC37A1 MET NCOR1 MTMR6 VPS13D POPDC3 USF2 ATP2B1	3.10e-05	195	184	9	1927_UP
Drug	LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A	LONP2 SEC24A NLRX1 HLCS NR3C1 SERPINA1 AP2S1 ZFYVE9 WDFY3	3.36e-05	197	184	9	1641_UP
Drug	Skimmianine [83-95-4]; Down 200; 15.4uM; PC3; HT_HG-U133A	SEL1L SLC37A1 SPTBN1 NR3C1 HIF1AN SLC25A37 VPS13D WDFY3 USF2	3.36e-05	197	184	9	5766_DN
Drug	fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A_EA	MBTPS1 ATR GNPTAB MTMR1 SKP2 MET TTC31 TLE3 SNX27	3.36e-05	197	184	9	1075_DN
Drug	Reserpinic acid hydrochloride; Down 200; 9.2uM; PC3; HT_HG-U133A	RPGRIP1L SPTBN1 VASH1 SERPINA1 SLC9A2 WDFY3 PLD2 PLEC DMPK	3.50e-05	198	184	9	6603_DN
Drug	Bromopride [4093-35-0]; Up 200; 11.6uM; HL60; HT_HG-U133A	ZBTB33 CYP26B1 TCN1 ARHGEF38 HLCS APBA3 SIPA1L1 MOB3B PLEC	3.50e-05	198	184	9	2182_UP
Drug	LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	ABCA2 RPGRIP1L NR3C1 SKP2 SBNO2 VPS13D AP2S1 PLCL2 DMPK	3.50e-05	198	184	9	996_UP
Disease	autosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)	VPS13C VPS13D	1.11e-04	3	180	2	DOID:0111611 (implicated_via_orthology)
Disease	Chediak-Higashi syndrome (implicated_via_orthology)	LYST WDFY3	2.20e-04	4	180	2	DOID:2935 (implicated_via_orthology)
Disease	Infiltrating duct carcinoma of female breast	SMG1 ATR MYLK4	2.74e-04	21	180	3	C3165106
Disease	myocardial infarction	KALRN CD109 PKD1L3 PLEKHG1 SERPINA1 TENM3 PLCL2 GMDS ATP2B1	3.17e-04	350	180	9	EFO_0000612
Disease	N-acetylglucosaminylasparagine measurement	GNPTAB SERPINA1	3.66e-04	5	180	2	EFO_0800151
Disease	Weight Gain	SPTBN1 VPS13D CD36 SIPA1L1 AHR	4.13e-04	102	180	5	C0043094
Disease	Prostatic Neoplasms	RNF130 MBTPS1 ATR RPN2 TOM1L1 NR3C1 TLR6 MET NCOR1 ALDH1A2 RALBP1 AHR	4.26e-04	616	180	12	C0033578
Disease	Malignant neoplasm of prostate	RNF130 MBTPS1 ATR RPN2 TOM1L1 NR3C1 TLR6 MET NCOR1 ALDH1A2 RALBP1 AHR	4.26e-04	616	180	12	C0376358
Disease	blood rubidium measurement	ABCA13 HIF1AN RIF1	5.23e-04	26	180	3	EFO_0021529
Disease	polycystic ovary syndrome (implicated_via_orthology)	NCOR1 CD36	5.46e-04	6	180	2	DOID:11612 (implicated_via_orthology)
Disease	lysophosphatidylethanolamine 17:0 measurement	SLC25A37 ALDH1A2	5.46e-04	6	180	2	EFO_0021465
Disease	lymphocyte count	SEL1L CA11 DOCK2 MIER2 PCDHGB5 KALRN LYST SBNO2 FOCAD NCOR1 ALDH1A2 SBNO1 DNAH17 ERCC6L2 PCDHGB4 NLRC5 PLEC CLEC16A VAV1 SPIC	6.50e-04	1464	180	20	EFO_0004587
Disease	corpus callosum central volume measurement	SLC9A2 PLEC CLEC16A	6.54e-04	28	180	3	EFO_0010296
Disease	immature platelet fraction	KALRN CAPZA2 CD36 PLEC VAV1	6.86e-04	114	180	5	EFO_0009187
Disease	epidermolysis bullosa simplex (is_implicated_in)	DST PLEC	7.62e-04	7	180	2	DOID:4644 (is_implicated_in)
Disease	immature platelet measurement	KALRN CAPZA2 CD36 PLEC VAV1	8.33e-04	119	180	5	EFO_0803541
Disease	serum alanine aminotransferase measurement, response to combination chemotherapy	MCM2 PLEKHG1 TMEM132D AHR	9.46e-04	71	180	4	EFO_0004735, EFO_0007965
Disease	TNF-related apoptosis-inducing ligand measurement	PTCHD4 SERPINA1 CBLN2 RNF138	9.97e-04	72	180	4	EFO_0008300
Disease	cerebrospinal fluid clusterin measurement	ABCA13 DST CSMD1	1.27e-03	35	180	3	EFO_0007657
Disease	coronary aneurysm	DOCK2 MYO3B CSMD1	1.27e-03	35	180	3	EFO_1000881
Disease	centronuclear myopathy X-linked (implicated_via_orthology)	MTMR1 MTMR6	1.30e-03	9	180	2	DOID:0111225 (implicated_via_orthology)
Disease	Adenocarcinoma of lung (disorder)	HK2 ATR RASA1 AHR VAV1 SFN	1.71e-03	206	180	6	C0152013
Disease	triglycerides to total lipids in large VLDL percentage	SERPINA1 ALDH1A2 NLRC5	1.74e-03	39	180	3	EFO_0022332
Disease	cleft lip	TAS2R16 ALDH1A2 DST TMEM132D CBLN2 ERCC6L2 CSMD1	1.87e-03	284	180	7	EFO_0003959
Disease	placenta growth factor measurement	RAPGEF5 EIF2B2	1.96e-03	11	180	2	EFO_0010626
Disease	Malignant neoplasm of breast	ABCA4 KALRN CD109 ARHGEF38 HLCS NCOR1 RIF1 SLC9A2 HOOK3 SBNO1 TLE3 SIPA1L1 AHR NLRC5 PLD2	2.52e-03	1074	180	15	C0006142
Disease	cholesterol to total lipids in large VLDL percentage	SERPINA1 ALDH1A2 NLRC5	2.62e-03	45	180	3	EFO_0022236
Disease	illegal drug consumption	TMEM132D CSMD1	2.76e-03	13	180	2	EFO_0005431
Disease	Primary Ciliary Dyskinesia	RPGRIP1L DNAI1 HYDIN	2.97e-03	47	180	3	C4551720
Disease	red blood cell density measurement	ATR KALRN MYO9A SPTBN1 CAPZA2 FOCAD ALDH1A2 DST TLE3 CD36 PLCL2 GMDS PLEC	3.02e-03	880	180	13	EFO_0007978
Disease	telomere length	SPTBN1 TERF2 TENM3 TMEM132D MYLK4 CFAP57 CSMD1	3.21e-03	313	180	7	EFO_0004505
Disease	Tobacco Dependence	PLEKHG1 AHR	3.21e-03	14	180	2	C0040332
Disease	triacylglycerol 46:2 measurement	MYO3B CSMD1	3.21e-03	14	180	2	EFO_0010402
Disease	triacylglycerol 54:2 measurement	MAU2 ALDH1A2	3.21e-03	14	180	2	EFO_0010420
Disease	Nicotine Dependence	PLEKHG1 AHR	3.21e-03	14	180	2	C0028043
Disease	Nicotine Use Disorder	PLEKHG1 AHR	3.21e-03	14	180	2	C0376384
Disease	mean corpuscular hemoglobin concentration	CYP26B1 ATR KALRN MAU2 SKP2 SLC25A37 MEFV DMXL1 FOCAD RIF1 SLC9A2 ALDH1A2 CD36 PLCL2 USF2	3.29e-03	1105	180	15	EFO_0004528
Disease	cholesteryl esters to total lipids in small VLDL percentage	SERPINA1 ALDH1A2 NLRC5	3.35e-03	49	180	3	EFO_0022256
Disease	neurotic disorder	TENM3 SIPA1L1 PLCL2 CSMD1	3.45e-03	101	180	4	EFO_0004257
Disease	multiple sclerosis	NR3C1 MET CSGALNACT2 CBLN2 PLCL2 NLRC5 POPDC3 PLEC CSMD1 CLEC16A	3.67e-03	594	180	10	MONDO_0005301
Disease	1,3,7-trimethylurate measurement	TRIM26 ALDH1A2	3.69e-03	15	180	2	EFO_0021172
Disease	lysophosphatidylethanolamine 18:0 measurement	MATN2 ALDH1A2	3.69e-03	15	180	2	EFO_0010367
Disease	cathepsin D measurement	GNPTAB MAU2	3.69e-03	15	180	2	EFO_0010611
Disease	immature platelet count	KALRN CAPZA2 CD36 PLEC	4.10e-03	106	180	4	EFO_0803544
Disease	idiopathic scoliosis (implicated_via_orthology)	MBTPS1 PPP2R3B	4.20e-03	16	180	2	DOID:0060250 (implicated_via_orthology)
Disease	Benign neoplasm of stomach	ATR MET	4.74e-03	17	180	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	ATR MET	4.74e-03	17	180	2	C0496905
Disease	Carcinoma in situ of stomach	ATR MET	4.74e-03	17	180	2	C0154060
Disease	caudal anterior cingulate cortex volume measurement	HECW1 FAT2	4.74e-03	17	180	2	EFO_0010289
Disease	large artery stroke	MBTPS1 TOM1L1 SERPINA1 PCCA	5.15e-03	113	180	4	EFO_0005524
Disease	esophageal adenocarcinoma	HECW1 SPARCL1	5.31e-03	18	180	2	EFO_0000478
Disease	trait in response to apixaban	MIER2 NR3C1 TLE3 MYO3B	5.47e-03	115	180	4	OBA_2050328
Disease	Insulin Resistance	NR4A3 CD36 AHR	5.92e-03	60	180	3	C0021655
Disease	Insulin Sensitivity	NR4A3 CD36 AHR	5.92e-03	60	180	3	C0920563

Protein segments in the cluster

Peptide	Gene	Start	Entry
INHKITEEGYRNFFQ	NAIP	1301	Q13075
QYNVFTDLHGISQEF	AHR	671	P35869
EFFQHSYTAILNQDF	ACOX2	366	Q99424
HLSQEYQLAAETFNL	ADAL	301	Q6DHV7
NQLYLHFQSDISVAA	CSMD1	1886	Q96PZ7
ITFYENQITAFLGHN	ABCA4	951	P78363
GLALNFSVFHYEIAN	SFN	171	P31947
LDYAVEQAHQGVFFN	ALDH1A2	301	O94788
ETLEEAFHYIFNVQL	ADD3	301	Q9UEY8
AFHYIFNVQLACEIQ	ADD3	306	Q9UEY8
EFAFSLYRQLAHQSN	SERPINA1	56	P01009
QEVDEQIFYAVHAFQ	ARHGEF38	711	Q9NXL2
NVYLNEVQVADFASF	GZF1	76	Q9H116
AVADLLLQAYQFHAA	BTBD17	281	A6NE02
HVFYAEDAQLIAQAI	APBA3	331	O96018
NNIDFFTVVSQLFFH	ABCA13	2381	Q86UQ4
AEVQLIHFNQELYGN	CA11	156	O75493
FVNQLAVHYTQVGNL	DNAI1	96	Q9UI46
LQNNFIEYISFIHQY	C2orf73	141	Q8N5S3
QSQGEIDFSFVYLAH	DMXL1	216	Q9Y485
QIFRNLENVYDQFVH	IQCA1	51	Q86XH1
DYQHLLVNSIANFFR	ARMCX2	501	Q7L311
NILGHAFYQLVVVFT	ATP2B1	931	P20020
ADFVALLDQFGNHYI	ASTN1	851	O14525
NNLAYLEAIHNFVEV	AP2S1	76	P53680
LEAIHNFVEVLNEYF	AP2S1	81	P53680
NFVEVLNEYFHNVCE	AP2S1	86	P53680
EFSNPFFVNYENHVL	MTMR1	571	Q13613
QISNRVLYVFFTHVQ	RALBP1	351	Q15311
EADINQLTEFFSYEH	PPP2R3B	301	Q9Y5P8
FQIVVQHFSEEHYIF	RASA1	541	P20936
RAAFHNAVAVVIYNN	RNF130	121	Q86XS8
QDFFQEAKTLIAQHY	IQCM	21	A0A1B0GVH7
LYLTDAEAQQFLHFV	LARGE2	461	Q8N3Y3
FEAVAENPLNFYHVN	PCDHGB4	106	Q9UN71
QINIHNLSAFYDSEL	MCM2	871	P49736
AVHVVDFFNRINLIY	MOB3B	61	Q86TA1
YFRTLFQQHNEAVNV	PAQR7	61	Q86WK9
FIEEAVRYHNNLAAQ	KLHL36	266	Q8N4N3
EQNHNFTDHYLNVAF	LONP2	466	Q86WA8
FTDHYLNVAFDLSQV	LONP2	471	Q86WA8
SNFAVQHRYLFEEDN	MATN2	876	O00339
ELHIFRVFTNNQVSY	MBTPS1	271	Q14703
VAERTYNNIFQFHQL	MCM8	786	Q9UJA3
NFTSQYLVHVNDLFL	RPGRIP1L	656	Q68CZ1
AYNLFAVNGILFNHE	GMDS	196	O60547
IHFNLTFQNTNDEEF	GNPTAB	611	Q3T906
QQFVHFTQLDLSYLQ	MGAT1	336	P26572
YFHQLFSVAGQVVEL	ZBTB33	56	Q86T24
HFASVVNSFIEKENY	NUDT15	76	Q9NV35
TPAHYDEQQNFFAQI	HIF1AN	196	Q9NWT6
YSNIRFQFVGIENIH	MTMR6	261	Q9Y217
QSNLANLEHAFYVAE	DST	206	Q03001
YAQEKQDFVQHFSQI	FDPS	76	P14324
NFERYQHNRDLVNFI	HECW1	996	Q76N89
SHVANNIFYFDEQII	CFAP57	16	Q96MR6
DLGHLFEVYQQFVDN	CYP26B1	206	Q9NR63
FSSEHFNLEIYRQNL	HLCS	446	P50747
LLAYFFTELNHDQVQ	HK2	6	P52789
VYILLDESNFNHFLN	FAM83B	176	Q5T0W9
QEHSAFRFAVQLYNT	GRIA3	46	P42263
YLILSGNQDRHFFIN	FAT2	2416	Q9NYQ8
RQILFGNTVHVFSYN	MINDY4B	106	A8MYZ0
QLSHVNLIQLYDAFE	MYLK3	566	Q32MK0
GNIQEIYDFHNNIFL	KALRN	1331	O60229
NQDQFYLLSAHISER	MYRFL	376	Q96LU7
NQLDHANLIQLYDAF	MYLK4	156	Q86YV6
DAFLEQAVSYQQFVD	LPIN1	481	Q14693
HEVVENLLNYCFQTF	NR3C1	726	P04150
YFLEQQEHFFVASLE	MEFV	471	O15553
FHYEFQNQRFSAEVL	NLRX1	681	Q86UT6
FEAVAENPLNFYHVN	PCDHGB5	106	Q9Y5G0
VNDNAPVFHQASYLV	PCDHGB5	441	Q9Y5G0
VQNEQFDLIVNAFSY	OVOS2	791	Q6IE36
SLFVAFQLRAQHFQE	PCCA	531	P05165
YNHEILGQQINDFTL	HOOK3	86	Q86VS8
YVNFVNEVFHQAFLL	RALGAPA2	401	Q2PPJ7
SVEGFRQALYQFLHN	IP6K3	276	Q96PC2
DVVFNYLHATAFQGT	UQCRC1	181	P31930
ITQLHFAFQDENYLY	DMPK	131	Q09013
QQTGYAFTHLSLQEF	NLRC5	506	Q86WI3
EEQNLVAFQYHRQIF	PRDM9	326	Q9NQV7
NIHSFGFYVVTQVIN	SLC37A1	151	P57057
YFLDVVQQANTIFHL	EXOC5	481	O00471
YRFVNNNLSQVIHDA	ADAM30	216	Q9UKF2
HYQQVFNGLSILASF	ATR	1086	Q13535
FHNYTLVSLNEEFNR	CSGALNACT2	331	Q8N6G5
RNVSTNVFFKQHDYI	CD109	336	Q6YHK3
QISFTFYGHANIIAQ	HYDIN	1346	Q4G0P3
HFNTVLEAYIQQHFS	DOCK2	691	Q92608
HYVFNLRDLSNIFQG	DNAH17	2651	Q9UFH2
AVAAASHIYQNQFVQ	CD36	141	P16671
ENLDLFFSRVYNLHQ	ATG9A	41	Q7Z3C6
DHFIAQAAAENVFFV	FAM172A	276	Q8WUF8
YFDQVLVNIGNHFDL	CBLN2	116	Q8IUK8
NETFAFVGNVTHYAQ	ABCA2	476	Q9BZC7
YQNFVFEEDRLHSIQ	LYST	696	Q99698
QYHLQSNEFLRNVFE	IFRD1	386	O00458
AAAAGHEIIVQYFLN	ANKS3	176	Q6ZW76
HLQKETFATYVARFQ	IZUMO1	116	Q8IYV9
DFSFHYAQLQSNIIE	EIF2B2	121	P49770
QNHISYREEVFFNDA	ERCC6L2	1351	Q5T890
VEFAVHTFNQQSKDY	CST9L	51	Q9H4G1
KNTVHAIFDTQAIFY	CAPN6	556	Q9Y6Q1
FVHSFQDEKRQLAYQ	DNAJC22	266	Q8N4W6
VYHQTQLENFAAFIL	SLC22A25	31	Q6T423
AAFSYYEFLLHVQQQ	SEC24B	1251	O95487
FFLVLQVTHYLDAGQ	MAU2	231	Q9Y6X3
HQQNALFQYFADTLT	SBNO1	1116	A3KN83
SVTQYVFLAQRHFNI	DSEL	286	Q8IZU8
QFVHIAYQVRSITFA	POPDC3	91	Q9HBV1
QDHAEFSYVLNGILN	FOCAD	76	Q5VW36
FTHIFALVRYNQQND	GARNL3	326	Q5VVW2
DHQFNLAEILSQNYS	MIER2	41	Q8N344
AVHVVDFFNRINLIY	MOB3C	61	Q70IA8
YFNAAVNHVDFSQNV	SERPINI1	131	Q99574
AAGTDAEHVQQFYNL	NR4A3	426	Q92570
HAFESNNFIYFLTVQ	MET	251	P08581
ENFHQYQFQAHTVAL	TAS2R16	171	Q9NYV7
SNYSHVIFLNEEEFD	RIMBP2	416	O15034
LQENHQRVSIFFDYA	ATP6V1H	101	Q9UI12
QFEVTGQAFLYHQVR	PUS3	266	Q9BZE2
AYDNFLEHSNSVFLQ	TOM1L1	391	O75674
IYVFDLHGNRFNLVQ	TBC1D31	66	Q96DN5
YHINNADVSFFLKEA	TMEM132D	51	Q14C87
EQNHQRAFDYFNLAA	SEL1L	391	Q9UBV2
SFEEQHISFALYVDN	NBPF20	5171	P0DPF2
VNQGDALEHNFSAIY	RIF1	666	Q5UIP0
SALSYYEFLLHIQQQ	SEC24A	1076	O95486
QYTFPNTRHQQEFAV	NCOR1	26	O75376
FINSSHNTYLIEDQF	PLCL2	436	Q9UPR0
VFAGQLEQNRYHSIF	PTCHD4	391	Q6ZW05
HYQAAFNNLEATQLA	SMG1	2566	Q96Q15
FQSIHFITYEFLQEQ	SLC25A37	211	Q9NYZ2
EEQNLVAFQYHRQIF	PRDM7	326	Q9NQW5
QLNRFQCSFEEAQHY	PKD1L3	36	Q7Z443
LNQRHQFDYGEFVNL	RNF138	211	Q8WVD3
YVNHLYVIDSQQALF	RAPGEF5	556	Q92565
FAHYDVQSILFDLNE	SIPA1L1	331	O43166
EVHKQNALFQYFSDT	SBNO2	976	Q9Y2G9
FQTFNASYDTINLHV	SI	1671	P14410
TALAIEHVRFFYQNI	SHCBP1	191	Q8NEM2
FYFEGNIHQSLQNIT	SPIC	76	Q8N5J4
HFDLLNYFAIAENES	SF3B5	46	Q9BWJ5
QQDLVNAQHFDAAYI	SNAPC1	111	Q16533
AEAFLNNQEYVLAHT	SPTBN1	1181	Q01082
AHAFAQYNLDQFTPV	CAPZA2	51	P47755
VGQLFNQHLDVFYLF	CHST1	76	O43916
NYVNSIIVHKFDFSD	CLEC16A	121	Q2KHT3
AFQLADGLQYIFAHV	PRPF8	571	Q6P2Q9
DCFQEFFQLNYLQHL	SKP2	326	Q13309
FVTQQQYRDHLFDKE	ZNF451	221	Q9Y4E5
LQQHDFTSQIFSLGY	TLE1	651	Q04724
ANYFILESQHTLSQF	WDFY3	416	Q8IZQ1
YEDLVTFLQQSIHQF	MINDY4	546	Q4G0A6
VATLVVTFHANFNYV	MPV17L	51	Q2QL34
FENIHVNEQLYILVF	SLC9A2	226	Q9UBY0
HQNFALFFQLVDVNT	RPN2	411	P04844
ELHAAAYVFTNDGQQ	SAGE1	16	Q9NXZ1
VHNYNITTVENFQHF	UBA5	146	Q9GZZ9
QAFLEAERAQSIAYH	SPARCL1	366	Q14515
ASHYNLDNLVAVFDV	TKTL2	171	Q9H0I9
FQLSIENLDQSLAHY	VAV1	386	P15498
LFNGNYSTAEVVNHF	TCN1	156	P20061
RFQEYHIQQNEALAA	TIMM9	66	Q9Y5J7
QQVDFYTAFLHHLAQ	UBR1	31	Q8IWV7
NDNDLAVTYFFHQAV	SNX27	371	Q96L92
AVLNNAFYLENLHFT	TENM3	2526	Q9P273
NQIVSLQFDFHFESL	VPS13C	1931	Q709C8
NFHVFLEYDQDLSVR	SNX5	161	Q9Y5X3
QYIVAEFEQGHQFLR	TRIM26	186	Q12899
HNVLFNVSNRFSEYL	USP9Y	2091	O00507
VLYFAQSENIAAHEN	PHF11	56	Q9UIL8
IEAHLKENAAYFQFF	PLEC	851	Q15149
QAAFGDHNIQYQFRT	USF2	56	Q15853
VYFQDINVIFLGALH	nan	26	Q6ZUG5
LNFHVFLEYNQDLSV	SNX6	161	Q9UNH7
LQRNLQFHAFISYSE	TLR6	636	Q9Y2C9
DEFQFLQAQYHSLKV	TLE3	31	Q04726
RAQLSQYSQHFAFIA	ZZEF1	2316	O43149
RSALFGNIQDIYHFN	PLEKHG1	156	Q9ULL1
GNIQDIYHFNSELLQ	PLEKHG1	161	Q9ULL1
IHTLKNNFEADAYFV	ITFG1	426	Q8TB96
ELQYNHTGTQFFEIK	VASH1	131	Q7L8A9
RESQHFLYIENQFFI	PLD2	631	O14939
TAIAYEQHGFFEQAQ	TRRAP	2776	Q9Y4A5
SQFLGYQQHDSQELL	USP11	391	P51784
LAHPVIQNFSYETFQ	TERF2	246	Q15554
FNHFVQLYRDALAGN	ZFYVE9	996	O95405
AQNGFYHEAVVLFTQ	TTC31	316	Q49AM3
NHSAFEAAYQIVLDA	ZSWIM4	781	Q9H7M6
YVHTQRFQAEVVAFI	VPS13D	1976	Q5THJ4
RFQAEVVAFIQHFTQ	VPS13D	1981	Q5THJ4
IANEQIQYYFNQHVF	MYO3B	741	Q8WXR4
YAHLFDFIVERINQA	MYO5C	406	Q9NQX4
FANEHLQQFFVQHVF	MYO7B	456	Q6PIF6
QFCINFANERLQHYF	MYO9A	551	B2RTY4