Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCC3 ATP7A TMC3 SLC52A3 SLC9B2 HTR3D CACNA1H SLC4A9 ABCC10 ABCC1 TMC2 SLC35D2 KCNK16 OCA2 SLC7A7 SLC7A6 SLC7A14 SLC4A1 SLC30A6 SFXN5 SLC7A4 SLC7A3 SLC13A1 SLC16A2 SLC18A2 GSDMD ATP6V0A4 SLC15A5 SLC13A5 ATP1A3 ATP1A4 UNC80 SCN3B SLC35B1

2.86e-06118024434GO:0022857
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCC3 ATP7A SLC9B2 SLC4A9 ABCC10 ABCC1 SLC35D2 SLC7A6 SLC4A1 SLC30A6 SLC13A1 SLC16A2 SLC18A2 ATP6V0A4 SLC15A5 SLC13A5 ATP1A3 ATP1A4 SLC35B1

6.98e-0647724419GO:0022804
GeneOntologyMolecularFunctiontransporter activity

ABCC3 ATP7A TMC3 SLC52A3 SLC9B2 HTR3D CACNA1H SLC4A9 ABCC10 ABCC1 TMC2 SLC35D2 KCNK16 OCA2 SLC7A7 SLC7A6 ATP10A SLC7A14 SLC4A1 SLC30A6 SFXN5 SLC7A4 SLC7A3 SLC13A1 SLC16A2 SLC18A2 GSDMD ATP6V0A4 SLC15A5 SLC13A5 ATP1A3 ATP1A4 UNC80 SCN3B SLC35B1

7.44e-06128924435GO:0005215
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

ABCC3 SLC52A3 SLC4A9 ABCC1 SLC35D2 SLC7A7 SLC7A6 SLC7A14 SLC4A1 SFXN5 SLC7A3 SLC16A2 SLC13A5 SLC35B1

1.60e-0529324414GO:0008514
GeneOntologyMolecularFunctionbasic amino acid transmembrane transporter activity

SLC7A7 SLC7A6 SLC7A4 SLC7A3

9.04e-05202444GO:0015174
GeneOntologyMolecularFunctionABC-type glutathione S-conjugate transporter activity

ABCC3 ABCC10 ABCC1

9.65e-0582443GO:0015431
GeneOntologyMolecularFunctionsmall GTPase binding

RGPD4 ATP7A ARHGEF7 XPO6 DOCK1 DOCK2 RGPD2 RANBP2 IPO7 XPO4 GCC2 HPS6 IPO11

1.71e-0432124413GO:0031267
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC3 ABCC10 ABCC1

2.03e-04102443GO:0043225
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC9B2 CACNA1H SLC4A9 SLC13A1 SLC18A2 SLC13A5 ATP1A3 ATP1A4 SCN3B

2.62e-041712449GO:0015081
GeneOntologyMolecularFunctionantiporter activity

SLC9B2 SLC4A9 SLC35D2 SLC7A6 SLC4A1 SLC30A6 SLC18A2 SLC35B1

3.00e-041382448GO:0015297
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC9B2 SLC4A9 SLC35D2 SLC7A6 SLC4A1 SLC30A6 SLC13A1 SLC16A2 SLC18A2 SLC15A5 SLC13A5 SLC35B1

3.01e-0429624412GO:0015291
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCC3 ATP7A ABCC10 ABCC1 ATP6V0A4 ATP1A3 ATP1A4

3.86e-041092447GO:0042626
GeneOntologyMolecularFunctionUDP-glucose transmembrane transporter activity

SLC35D2 SLC35B1

4.43e-0432442GO:0005460
GeneOntologyMolecularFunctionhedgehog receptor activity

PTCH1 PTCH2

4.43e-0432442GO:0008158
GeneOntologyMolecularFunctionhistone H2AXS139 kinase activity

ATR ATM

4.43e-0432442GO:0035979
GeneOntologyMolecularFunctionglycogen phosphorylase activity

PYGB PYGM

4.43e-0432442GO:0008184
GeneOntologyMolecularFunctionL-arginine transmembrane transporter activity

SLC7A7 SLC7A6 SLC7A3

4.71e-04132443GO:0061459
GeneOntologyMolecularFunctionGTPase binding

RGPD4 ATP7A ARHGEF7 XPO6 DOCK1 DOCK2 RGPD2 RANBP2 IPO7 XPO4 GCC2 HPS6 IPO11

5.15e-0436024413GO:0051020
GeneOntologyMolecularFunctionnucleocytoplasmic carrier activity

TMCO6 XPO6 XPO4 IPO11

5.98e-04322444GO:0140142
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCC3 ABCC10 ABCC1

7.36e-04152443GO:0008559
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCC3 ABCC10 ABCC1 SLC18A2

7.56e-04342444GO:0042910
GeneOntologyMolecularFunctionsmoothened binding

PTCH1 PTCH2

8.78e-0442442GO:0005119
GeneOntologyMolecularFunctiontricarboxylic acid transmembrane transporter activity

SFXN5 SLC13A5

8.78e-0442442GO:0015142
GeneOntologyMolecularFunctioncitrate transmembrane transporter activity

SFXN5 SLC13A5

8.78e-0442442GO:0015137
GeneOntologyMolecularFunctionhedgehog family protein binding

PTCH1 PTCH2

8.78e-0442442GO:0097108
GeneOntologyMolecularFunctionolfactory receptor activity

OR2T11 OR4D5 OR5B21 OR4D6 OR8J1 OR52K1 OR6C2 OR52N4 OR56A5 OR56A3 OR6K3 OR56A4 OR52K2 OR5D13

8.95e-0443124414GO:0004984
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP7A ATP6V0A4 ATP1A3 ATP1A4

9.42e-04362444GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP7A ATP6V0A4 ATP1A3 ATP1A4

9.42e-04362444GO:0015662
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

ABCC3 ABCC1 SLC7A7 SLC7A6 SLC7A14 SFXN5 SLC7A3 SLC16A2 SLC13A5

1.04e-032072449GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

ABCC3 ABCC1 SLC7A7 SLC7A6 SLC7A14 SFXN5 SLC7A3 SLC16A2 SLC13A5

1.08e-032082449GO:0005342
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

ABCC3 SLC4A9 ABCC10 ABCC1 OCA2 SLC4A1 SLC13A1 SLC18A2

1.23e-031712448GO:0015103
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

ATP7A SLC9B2 SLC4A9 SLC4A1 SLC30A6 SLC13A1 SLC18A2 ATP6V0A4 SLC13A5 ATP1A3 ATP1A4

1.25e-0330124411GO:0022853
GeneOntologyMolecularFunctionadenylate cyclase activity

ADCY10 ADCY4 GUCY2D

1.28e-03182443GO:0004016
GeneOntologyMolecularFunctionG protein-coupled receptor activity

ADGRG5 OR2T11 ADRB3 C3AR1 OR4D5 GPR6 NPR3 TMEM116 F2RL3 OR5B21 GPR143 OR4D6 OR8J1 OR52K1 OR6C2 OR52N4 OR56A5 OR56A3 OR6K3 OR56A4 OR52K2 OR5D13

1.29e-0388424422GO:0004930
GeneOntologyMolecularFunction1,4-alpha-oligoglucan phosphorylase activity

PYGB PYGM

1.45e-0352442GO:0004645
GeneOntologyMolecularFunctionhistone H2AX kinase activity

ATR ATM

1.45e-0352442GO:0141003
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD4 RGPD2 RANBP2

1.76e-03202443GO:0061665
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

ATP7A TMC3 SLC9B2 HTR3D CACNA1H SLC4A9 TMC2 KCNK16 OCA2 SLC4A1 SLC30A6 SFXN5 SLC13A1 SLC18A2 ATP6V0A4 SLC13A5 ATP1A3 ATP1A4 UNC80 SCN3B

1.83e-0379324420GO:0015075
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC7A7 SLC7A6 SLC7A14 SLC7A4 SLC7A3 SLC16A2

1.84e-031052446GO:0015171
GeneOntologyMolecularFunctionpeptidyltransferase activity

GGT3P GGT2P

2.16e-0362442GO:0000048
GeneOntologyMolecularFunctionleukotriene-C(4) hydrolase

GGT3P GGT2P

2.16e-0362442GO:0002951
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

ADGRG5 PTCH1 OR2T11 ADRB3 HTR3D C3AR1 OR4D5 PLXNA3 MRC1 GPR6 NPR3 TMEM116 F2RL3 OR5B21 GPR143 OR4D6 OR8J1 OR52K1 OR6C2 OR52N4 OR56A5 PTCH2 OR56A3 ROBO1 CD300LG OR6K3 OR56A4 OR52K2 OR5D13

2.28e-03135324429GO:0004888
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ABCC3 ATP7A SLC9B2 CACNA1H SLC4A9 ABCC10 ABCC1 TMC2 KCNK16 OCA2 SLC4A1 SLC30A6 SLC13A1 SLC18A2 ATP6V0A4 SLC13A5 ATP1A3 ATP1A4 SCN3B

2.53e-0375824419GO:0015318
GeneOntologyMolecularFunctionsterol ester esterase activity

LDAH LIPE

3.00e-0372442GO:0004771
GeneOntologyMolecularFunctionsplicing factor binding

SF3B1 UHMK1

3.00e-0372442GO:1990935
GeneOntologyMolecularFunctioncyclase activity

ADCY10 ADCY4 GUCY2D

3.02e-03242443GO:0009975
GeneOntologyMolecularFunctionphosphorus-oxygen lyase activity

ADCY10 ADCY4 GUCY2D

3.40e-03252443GO:0016849
GeneOntologyBiologicalProcessorganic anion transport

ADCY10 ABCC3 SLC52A3 SLC4A9 ABCC10 ABCC1 SLC35D2 SLC7A7 SLC7A6 SELENON SLC7A14 SLC4A1 SFXN5 SLC7A3 SLC16A2 SLC13A5 ATP1A3 SLC35B1

4.26e-0551524318GO:0015711
GeneOntologyBiologicalProcessleukotriene transport

ABCC3 ABCC10 ABCC1

5.46e-0572433GO:0071716
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

ABCC3 ATP7A WNK1 TMC3 PIK3CG SLC9B2 HTR3D CACNA1H SLC4A9 ABCC10 ABCC1 TMC2 F2RL3 KCNK16 OCA2 SELENON ATP10A SLC4A1 SLC30A6 SFXN5 SLC13A1 SLC18A2 ATP6V0A4 SLC13A5 ATP1A3 ATP1A4 UNC80 PRNP SCN3B

5.46e-05111524329GO:0034220
GeneOntologyBiologicalProcessbasic amino acid transmembrane transport

SLC7A7 SLC7A6 SLC7A4 SLC7A3

6.34e-05192434GO:1990822
GeneOntologyBiologicalProcessbasic amino acid transport

SLC7A7 SLC7A6 SLC7A4 SLC7A3

1.16e-04222434GO:0015802
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD4 RGPD2 RANBP2

1.29e-0492433GO:0033133
GeneOntologyBiologicalProcesstelomerase catalytic core complex assembly

ATR ATM

1.38e-0422432GO:1904868
GeneOntologyBiologicalProcesspositive regulation of telomerase catalytic core complex assembly

ATR ATM

1.38e-0422432GO:1904884
GeneOntologyBiologicalProcessregulation of telomerase catalytic core complex assembly

ATR ATM

1.38e-0422432GO:1904882
GeneOntologyBiologicalProcessneural plate axis specification

PTCH1 C2CD3

1.38e-0422432GO:0021997
GeneOntologyBiologicalProcesscyclic nucleotide biosynthetic process

ADCY10 NPPB ADCY4 GUCY2D

1.40e-04232434GO:0009190
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RGPD2 RANBP2

8.74e-0582473GO:1990723
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RGPD2 RANBP2

1.84e-04102473GO:0044614
MousePhenopremature death

STK36 ATP7A ATR EXT1 PTCH1 GGT3P CHUK SLC52A3 RINT1 AGA PARL UNC93B1 ALOX15 FOXP3 NPR3 COL10A1 ROGDI SALL4 E2F4 OCA2 SLC7A7 RFX4 GGT2P SLC4A1 SLC18A2 NEK8 ATP6V0A4 ATM ATP1A3 CTSD PRNP

1.39e-05105118231MP:0002083
MousePhenosmall thymus

STK36 ATR PIK3CG PARL PNP FOXP3 DOCK1 COL10A1 E2F4 HPS6 ATM CTSD TOP2A NCKAP1L

2.28e-0528618214MP:0000706
MousePhenomale infertility

ADCY10 STK36 ATP7A KATNB1 PTCH1 QRICH2 GGT3P PGAP1 HERC2 HERC1 TRIM36 CSTF2T FOXP3 MROH9 DNHD1 XPO4 PIWIL2 OCA2 CFAP43 TDRD1 ATP10A GGT2P LIPE ATM SPIDR ATP1A4 CDC34 PRNP

3.47e-0594418228MP:0001925
MousePhenodecreased double-positive T cell number

PARL PNP FOXP3 COL10A1 E2F4 ATM CTSD NCKAP1L

7.20e-051061828MP:0005092
MousePhenoaciduria

GGT3P SLC52A3 AGA DHTKD1 SLC7A7 GGT2P

7.66e-05551826MP:0010028
MousePhenoabnormal double-positive T cell morphology

PARL PNP FOXP3 COL10A1 E2F4 CD8A ATM CTSD NCKAP1L

8.46e-051391829MP:0002408
MousePhenoabnormal spleen red pulp morphology

GGT3P ABCC10 ALOX15 FOXP3 COL10A1 SLC7A7 GGT2P SF3B1

9.36e-051101828MP:0002356
MousePhenoabnormal blastocyst hatching

RGPD4 CDK11A DPAGT1 RGPD2 RANBP2 POLD2 SALL4 TMX2

1.13e-041131828MP:0003693
MousePhenobradykinesia

IREB2 FOXP3 SLC18A2 LTN1 CTSD

1.25e-04381825MP:0005156
MousePhenomosaic coat color

ATP7A OCA2

1.69e-0421822MP:0010389
MousePhenodecreased susceptibility to prion infection

ATP7A PRNP

1.69e-0421822MP:0005363
MousePhenonervous

GGT3P OCA2 GGT2P

1.72e-0491823MP:0008912
MousePhenodiluted coat color

ATP7A GGT3P SZT2 OCA2 GGT2P HPS6

1.80e-04641826MP:0000371
DomainARM-type_fold

STK36 ATR TMCO6 URB1 PIK3CG XPO6 NCAPD2 NOC4L TBCD DOCK1 DOCK2 MROH9 IPO7 COPB1 XPO4 HEATR1 SF3B1 MROH1 MROH2B LTN1 ATM IPO11

6.76e-1033924322IPR016024
DomainARM-like

STK36 ATR TMCO6 XPO6 NCAPD2 NOC4L TBCD DOCK2 MROH9 IPO7 COPB1 XPO4 HEATR1 SF3B1 MROH1 MROH2B LTN1 IPO11

1.69e-0827024318IPR011989
Domain-

STK36 ATR TMCO6 XPO6 NCAPD2 TBCD MROH9 IPO7 COPB1 XPO4 HEATR1 SF3B1 MROH1 MROH2B IPO11

2.28e-07222243151.25.10.10
DomainAA_permease_2

SLC7A7 SLC7A6 SLC7A14 SLC7A4 SLC7A3

4.23e-07132435PF13520
DomainAA/rel_permease1

SLC7A7 SLC7A6 SLC7A14 SLC7A4 SLC7A3

4.23e-07132435IPR002293
DomainHEAT

STK36 ATR NCAPD2 TBCD HEATR1 SF3B1 MROH1 IPO11

8.00e-07582438IPR000357
DomainHEAT

STK36 ATR NCAPD2 TBCD HEATR1 SF3B1 MROH1

2.71e-06482437PF02985
DomainAA-permease/SLC12A_dom

SLC7A7 SLC7A6 SLC7A14 SLC7A4 SLC7A3

7.86e-06222435IPR004841
DomainAA_permease

SLC7A7 SLC7A6 SLC7A14 SLC7A4 SLC7A3

7.86e-06222435PF00324
DomainCAT3

SLC7A14 SLC7A4 SLC7A3

2.13e-0552433IPR015606
DomainAA_permease_C

SLC7A14 SLC7A4 SLC7A3

2.13e-0552433PF13906
DomainCAT_C

SLC7A14 SLC7A4 SLC7A3

2.13e-0552433IPR029485
DomainHEAT_REPEAT

ATR TBCD HEATR1 SF3B1 MROH1 MROH2B IPO11

3.46e-05702437PS50077
DomainRab_bind

RGPD4 RGPD2 GCC2

7.33e-0572433PF16704
DomainGCC2_Rab_bind

RGPD4 RGPD2 GCC2

7.33e-0572433IPR032023
DomainRCC1

HERC3 HERC2 HERC1 NEK8

1.15e-04202434PF00415
DomainRCC1_1

HERC3 HERC2 HERC1 NEK8

1.41e-04212434PS00625
DomainRCC1_2

HERC3 HERC2 HERC1 NEK8

1.41e-04212434PS00626
DomainRCC1_3

HERC3 HERC2 HERC1 NEK8

1.41e-04212434PS50012
DomainTM_rcpt_patched

PTCH1 PTCH2

1.69e-0422432IPR004766
DomainGamma_tubulin

TUBG2 TUBG1

1.69e-0422432IPR002454
Domain-

HERC3 HERC2 HERC1 NEK8

1.70e-042224342.130.10.30
DomainReg_chr_condens

HERC3 HERC2 HERC1 NEK8

1.70e-04222434IPR000408
DomainRCC1/BLIP-II

HERC3 HERC2 HERC1 NEK8

2.04e-04232434IPR009091
Domain-

RGPD4 RGPD2 GCC2

2.44e-041024331.10.220.60
DomainGrip

RGPD4 RGPD2 GCC2

3.32e-04112433SM00755
DomainGRIP

RGPD4 RGPD2 GCC2

3.32e-04112433PF01465
DomainRan_BP1

RGPD4 RGPD2 RANBP2

4.39e-04122433PF00638
DomainRANBD1

RGPD4 RGPD2 RANBP2

4.39e-04122433PS50196
DomainGRIP_dom

RGPD4 RGPD2 GCC2

4.39e-04122433IPR000237
DomainGRIP

RGPD4 RGPD2 GCC2

4.39e-04122433PS50913
DomainPHOSPHORYLASE

PYGB PYGM

5.01e-0432432PS00102
DomainGlycg_phsphrylas

PYGB PYGM

5.01e-0432432IPR011833
DomainGlyco_trans_35

PYGB PYGM

5.01e-0432432IPR000811
DomainIon_channel_UNC-93

UNC93A UNC93B1

5.01e-0432432IPR010291
DomainPhosphorylase

PYGB PYGM

5.01e-0432432PF00343
DomainNa/sul_symport_CS

SLC13A1 SLC13A5

5.01e-0432432IPR031312
DomainUNC-93

UNC93A UNC93B1

5.01e-0432432PF05978
DomainNA_SULFATE

SLC13A1 SLC13A5

5.01e-0432432PS01271
DomainRanBD

RGPD4 RGPD2 RANBP2

5.65e-04132433SM00160
DomainRan_bind_dom

RGPD4 RGPD2 RANBP2

5.65e-04132433IPR000156
DomainOlfact_rcpt

OR2T11 OR4D5 OR5B21 OR4D6 OR8J1 OR52K1 OR6C2 OR52N4 OR56A5 OR56A3 OR6K3 OR56A4 OR52K2 OR5D13

6.68e-0439324314IPR000725
DomainIMPORTIN_B_NT

XPO6 IPO7 IPO11

7.12e-04142433PS50166
Domain-

ATP7A ATP10A ATP1A3 ATP1A4

7.55e-043224343.40.1110.10
Domain-

ATP7A ATP10A ATP1A3 ATP1A4

7.55e-043224342.70.150.10
DomainPI3/4_kinase_CS

ATR PIK3CG ATM

8.82e-04152433IPR018936
DomainIBN_N

XPO6 IPO7 IPO11

8.82e-04152433PF03810
DomainMultidrug-R_assoc

ABCC3 ABCC1

9.94e-0442432IPR005292
DomainATPase_P-typ_cyto_domN

ATP7A ATP10A ATP1A3 ATP1A4

1.07e-03352434IPR023299
Domain-

ATR PIK3CG ATM

1.07e-031624331.10.1070.11
DomainIBN_N

XPO6 IPO7 IPO11

1.07e-03162433SM00913
DomainPI3Kc

ATR PIK3CG ATM

1.07e-03162433SM00146
DomainATPase_P-typ_P_site

ATP7A ATP10A ATP1A3 ATP1A4

1.19e-03362434IPR018303
DomainP_typ_ATPase

ATP7A ATP10A ATP1A3 ATP1A4

1.19e-03362434IPR001757
DomainATPASE_E1_E2

ATP7A ATP10A ATP1A3 ATP1A4

1.19e-03362434PS00154
DomainImportin-beta_N

XPO6 IPO7 IPO11

1.29e-03172433IPR001494
DomainATPase_P-typ_transduc_dom_A

ATP7A ATP10A ATP1A3 ATP1A4

1.32e-03372434IPR008250
DomainE1-E2_ATPase

ATP7A ATP10A ATP1A3 ATP1A4

1.32e-03372434PF00122
DomainPI3_PI4_kinase

ATR PIK3CG ATM

1.54e-03182433PF00454
DomainPI3_4_KINASE_1

ATR PIK3CG ATM

1.54e-03182433PS00915
DomainPI3_4_KINASE_2

ATR PIK3CG ATM

1.54e-03182433PS00916
Domain-

ADCY10 ADCY4 GUCY2D

1.54e-031824333.30.70.1230
DomainPI3/4_kinase_cat_dom

ATR PIK3CG ATM

1.54e-03182433IPR000403
DomainPI3_4_KINASE_3

ATR PIK3CG ATM

1.54e-03182433PS50290
DomainNucleotide_cyclase

ADCY10 ADCY4 GUCY2D

1.54e-03182433IPR029787
DomainDOCK_N

DOCK1 DOCK2

1.64e-0352432PF16172
DomainNa/sul_symport

SLC13A1 SLC13A5

1.64e-0352432IPR001898
DomainDOCK_N

DOCK1 DOCK2

1.64e-0352432IPR032376
DomainNa_sulph_symp

SLC13A1 SLC13A5

1.64e-0352432PF00939
DomainFATC

ATR ATM

1.64e-0352432PF02260
DomainGuanylate_cyc

ADCY10 ADCY4 GUCY2D

1.81e-03192433PF00211
DomainGUANYLATE_CYCLASE_2

ADCY10 ADCY4 GUCY2D

1.81e-03192433PS50125
DomainA/G_cyclase

ADCY10 ADCY4 GUCY2D

1.81e-03192433IPR001054
DomainGUANYLATE_CYCLASE_1

ADCY10 ADCY4 GUCY2D

1.81e-03192433PS00452
DomainCYCc

ADCY10 ADCY4 GUCY2D

1.81e-03192433SM00044
DomainFAT

ATR ATM

2.44e-0362432PS51189
DomainFATC

ATR ATM

2.44e-0362432PS51190
DomainFAT

ATR ATM

2.44e-0362432PF02259
DomainPIK-rel_kinase_FAT

ATR ATM

2.44e-0362432IPR003151
DomainFATC_dom

ATR ATM

2.44e-0362432IPR003152
DomainP-type_ATPase_IIC

ATP1A3 ATP1A4

2.44e-0362432IPR005775
DomainPIK_FAT

ATR ATM

2.44e-0362432IPR014009
DomainFATC

ATR ATM

2.44e-0362432SM01343
DomainGPCR_Rhodpsn_7TM

OR2T11 ADRB3 C3AR1 OR4D5 GPR6 F2RL3 OR5B21 OR4D6 OR8J1 OR52K1 OR6C2 OR52N4 OR56A5 OR56A3 OR6K3 OR56A4 OR52K2 OR5D13

3.04e-0367024318IPR017452
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ABCC3 STK36 TMEM8B TMCO6 PTCH1 WNK1 BIRC6 CIC TUBG1 SLC52A3 URB1 XPO6 NCAPD2 PYGB CACNA1H HERC2 HERC1 MMP17 ABCC10 TBCD PLXNA3 FLII SZT2 HECTD4 CFAP43 SH2B2 TLNRD1 INTS5 C2CD3 MROH1 NEK8 HPS6

2.32e-1111052493235748872
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ABCC3 ATR CD55 EXT1 RINT1 XPO6 PGAP1 TMEM131L SEC61B UNC93B1 UBIAD1 ITM2B RCE1 PLXNA3 ABCC1 NPR3 PIGS TMEM59 KIAA1549 SELENON TMX2 LTN1 DPY19L4 PAM ROBO1 ATM CTSD CDH13 PRNP

1.29e-0812012492935696571
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD4 RGPD2 RANBP2 TOP2A

3.14e-079249418394993
Pubmed

MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline.

TUBG2 TUBG1 PIWIL2 TDRD1

3.14e-079249421397847
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

OMA1 CD55 PTCH1 NEO1 PLXNA3 NPR3 PTCH2 ROBO1 CDH13

3.40e-07126249916284245
Pubmed

Profiling cancer gene mutations in longitudinal epithelial ovarian cancer biopsies by targeted next-generation sequencing: a retrospective study.

ATR ATM TOP2A

3.63e-073249325846551
Pubmed

Defining the membrane proteome of NK cells.

ATP7A ACP2 KATNB1 BIRC6 LAX1 PIK3CG NCAPD2 PYGB HERC2 ITM2B LRRC41 RCE1 DOCK2 ABCC1 RANBP2 IPO7 COPB1 PIGS HEATR1 INTS5 GCC2 HPS6 PAM ABHD13 NCKAP1L

1.27e-0611682492519946888
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR4D5 OR5B21 OR4D6 OR8J1 OR52K1 OR6C2 OR52N4 OR56A5 OR56A3 OR6K3 OR56A4 OR52K2 OR5D13

1.37e-063432491332295537
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

BIRC6 TUBG1 RINT1 NCAPD2 SEC61B UBIAD1 HERC2 RANBP2 IPO7 PIGS TMEM59 XPO4 HEATR1 SLC7A6 SF3B1 GCC2 LTN1 IPO11

1.47e-066572491836180527
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR4D5 OR5B21 OR4D6 OR8J1 OR52K1 OR6C2 OR52N4 OR56A5 OR56A3 OR6K3 OR56A4 OR52K2 OR5D13

1.51e-063462491314611657
Pubmed

Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.

MBL2 CD55 SERPING1 C3AR1 C4BPA

2.64e-0631249519344414
Pubmed

EXT1 regulates chondrocyte proliferation and differentiation during endochondral bone development.

EXT1 PTCH1 COL10A1

3.59e-065249315777636
Pubmed

Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse.

OR52K1 OR56A5 OR56A3 OR56A4 OR52K2

3.64e-0633249517350283
Pubmed

Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells.

CD55 C3AR1 FOXP3

7.14e-066249323382542
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR4D5 OR5B21 OR4D6 OR8J1 OR52K1 OR6C2 OR52N4 OR56A5 OR56A3 OR6K3 OR56A4 OR52K2

7.21e-063402491211875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR4D5 OR5B21 OR4D6 OR8J1 OR52K1 OR6C2 OR52N4 OR56A5 OR56A3 OR6K3 OR56A4 OR52K2

7.21e-063402491211802173
Pubmed

Centrosome-related genes, genetic variation, and risk of breast cancer.

TUBG2 KATNB1 CDK11A TUBG1 CHUK PIK3CG NCAPD2

9.18e-06102249720508983
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

ATR ACP2 EXT1 LDAH KIAA0319 NEO1 SEC61B UNC93B1 UBIAD1 HERC1 ITM2B ABCC10 COG7 PIGS SLC7A6 INTS5 MROH1 HPS6 LTN1 DPY19L4 ATM IPO11

9.30e-0610612492233845483
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD4 RGPD2 RANBP2

1.24e-05724939037092
Pubmed

Characterization of two patched receptors for the vertebrate hedgehog protein family.

STK36 PTCH1 PTCH2

1.24e-05724939811851
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD4 RGPD2 RANBP2

1.24e-057249321205196
Pubmed

Centrosomal localization of DNA damage checkpoint proteins.

ATR TUBG1 ATM

1.24e-057249317171639
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD4 RGPD2 RANBP2

1.24e-057249324403063
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RGPD4 RGPD2 RANBP2

1.24e-057249323536549
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RGPD4 RGPD2 RANBP2

1.24e-057249312191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RGPD4 RGPD2 RANBP2

1.24e-057249322821000
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD4 RGPD2 RANBP2

1.24e-057249311353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RGPD4 RGPD2 RANBP2

1.24e-057249330944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RGPD4 RGPD2 RANBP2

1.24e-057249338838144
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RGPD4 RGPD2 RANBP2

1.24e-05724937559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RGPD4 RGPD2 RANBP2

1.24e-057249317372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RGPD4 RGPD2 RANBP2

1.24e-057249338657106
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD4 RGPD2 RANBP2

1.24e-057249318949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD4 RGPD2 RANBP2

1.24e-057249325187515
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD4 RGPD2 RANBP2

1.24e-05724938603673
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD4 RGPD2 RANBP2

1.24e-057249326632511
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD4 RGPD2 RANBP2

1.24e-057249323818861
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RGPD4 RGPD2 RANBP2

1.24e-057249320682751
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

STK36 WNK1 BIRC6 MYO15B DHTKD1 CSTF2T DOCK2 ATP10A SLC7A14 LTN1 SPIDR MORC3 UNC80 SCN3B

1.48e-054932491415368895
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

RGPD4 ATR CDK11A NOC4L FOXP3 RGPD2 RANBP2 COPB1 HEATR1 ELF1 ATM NCKAP1L

1.67e-053702491222922362
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

TUBG1 RINT1 URB1 XPO6 NCAPD2 UBIAD1 ITM2B ANAPC5 TBCD ABCC1 RANBP2 IPO7 COPB1 PIGS TMEM59 HEATR1 INTS5 TCF25 ATP1A3 IPO11

1.72e-059422492031073040
Pubmed

Cutting edge: Receptors for C3a and C5a modulate stability of alloantigen-reactive induced regulatory T cells.

CD55 C3AR1 FOXP3

1.98e-058249323690475
Pubmed

Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.

ABCC3 ABCC10 ABCC1

1.98e-058249315802388
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RGPD4 RGPD2 RANBP2

1.98e-058249321670213
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RGPD4 RGPD2 RANBP2

1.98e-058249327412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RGPD4 RGPD2 RANBP2

1.98e-058249321310149
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RGPD4 RGPD2 RANBP2

1.98e-058249322262462
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RGPD4 RGPD2 RANBP2

1.98e-058249328745977
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

ATR TUBG1 DDX46 MYO15B XPO6 NCAPD2 SEC23B DOCK1 DOCK2 RANBP2 IPO7 COPB1 SF3B1 ATM TOP2A

2.28e-055822491520467437
Pubmed

Centriolar Protein C2cd3 Is Required for Craniofacial Development.

TUBG2 TUBG1 C2CD3

2.95e-059249334211969
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RGPD4 RGPD2 RANBP2

2.95e-059249328100513
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RGPD4 RGPD2 RANBP2

2.95e-059249317887960
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RGPD4 RGPD2 RANBP2

2.95e-05924939733766
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RGPD4 RGPD2 RANBP2

2.95e-059249311553612
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RGPD4 RGPD2 RANBP2

2.95e-059249310601307
Pubmed

Autonomous and non-cell autonomous role of cilia in structural birth defects in mice.

TUBG2 PTCH1 TUBG1

2.95e-059249338079449
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RGPD4 RGPD2 RANBP2

2.95e-059249328877029
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

TUBG1 URB1 NOC4L CSTF2T DOCK2 FLII RANBP2 IPO7 COPB1 SF3B1 TOP2A

3.85e-053402491129478914
Pubmed

5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.

ATR TBCD XPO4 ATM

3.95e-0527249423027611
Pubmed

Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification.

EXT1 PTCH1 COL10A1

4.19e-0510249315177029
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RGPD4 RGPD2 RANBP2

4.19e-0510249316332688
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RGPD4 RGPD2 RANBP2

4.19e-0510249327160050
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RGPD4 RGPD2 RANBP2

4.19e-051024938857542
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RGPD4 RGPD2 RANBP2

4.19e-0510249321859863
Pubmed

Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks.

ATR ATM

5.11e-052249219285939
Pubmed

Enhanced 15-Lipoxygenase 1 Production is Related to Periostin Expression and Eosinophil Recruitment in Eosinophilic Chronic Rhinosinusitis.

ALOX15 POSTN

5.11e-052249233218117
Pubmed

Effects on sperm morphology by alleles at the pink-eyed dilution locus in mice.

HERC2 OCA2

5.11e-0522492863229
Pubmed

DNA damage induces a kinetochore-based ATM/ATR-independent SAC arrest unique to the first meiotic division in mouse oocytes.

ATR ATM

5.11e-052249228851706
Pubmed

Ataxia telangiectasia mutated-dependent regulation of topoisomerase II alpha expression and sensitivity to topoisomerase II inhibitor.

ATM TOP2A

5.11e-052249223163762
Pubmed

Induction of ATM/ATR pathway combined with Vγ2Vδ2 T cells enhances cytotoxicity of ovarian cancer cells.

ATR ATM

5.11e-052249224726882
Pubmed

The protein-specific activities of the transmembrane modules of Ptch1 and Ptch2 are determined by their adjacent protein domains.

PTCH1 PTCH2

5.11e-052249230166346
Pubmed

rRNA synthesis inhibitor, CX-5461, activates ATM/ATR pathway in acute lymphoblastic leukemia, arrests cells in G2 phase and induces apoptosis.

ATR ATM

5.11e-052249226061708
Pubmed

CD8+FOXP3+T cells from renal transplant recipients in quiescence induce immunoglobulin-like transcripts-3 and -4 on dendritic cells from their respective donors.

FOXP3 CD8A

5.11e-052249218089323
Pubmed

MTOC reorientation occurs during FcgammaR-mediated phagocytosis in macrophages.

TUBG2 TUBG1

5.11e-052249217442887
Pubmed

Functional significance for a heterogenous ribonucleoprotein A18 signature RNA motif in the 3'-untranslated region of ataxia telangiectasia mutated and Rad3-related (ATR) transcript.

ATR ATM

5.11e-052249220103595
Pubmed

Decay-Accelerating Factor Restrains Complement Activation and Delays Progression of Murine cBSA-Induced Membranous Nephropathy.

CD55 C3AR1

5.11e-052249237036696
Pubmed

Yonsei Criteria, a Potential Linkage to Intratumoral Foxp3⁺/CD8⁺ Ratio for the Prediction of Oncologic Outcomes in Resected Left-Sided Pancreatic Cancer.

FOXP3 CD8A

5.11e-052249232233171
Pubmed

Interplay between ATM and ATR in the regulation of common fragile site stability.

ATR ATM

5.11e-052249217934520
Pubmed

ATM and ATR activities maintain replication fork integrity during SV40 chromatin replication.

ATR ATM

5.11e-052249223592994
Pubmed

Bleomycin-induced over-replication involves sustained inhibition of mitotic entry through the ATM/ATR pathway.

ATR ATM

5.11e-052249219527713
Pubmed

ATM and ATR signaling at a glance.

ATR ATM

5.11e-052249226567218
Pubmed

Cancer genome datamining and functional genetic analysis implicate mechanisms of ATM/ATR dysfunction underpinning carcinogenesis.

ATR ATM

5.11e-052249233742106
Pubmed

Congenital embryonal rhabdomyosarcoma caused by heterozygous concomitant PTCH1 and PTCH2 germline mutations.

PTCH1 PTCH2

5.11e-052249229230040
Pubmed

Allocation of gamma-tubulin between oocyte cortex and meiotic spindle influences asymmetric cytokinesis in the mouse oocyte.

TUBG2 TUBG1

5.11e-052249217287496
Pubmed

Critical role for phosphoinositide 3-kinase gamma in parasite invasion and disease progression of cutaneous leishmaniasis.

PIK3CG FOXP3

5.11e-052249222232690
Pubmed

y+LAT1 and y+LAT2 contribution to arginine uptake in different human cell models: Implications in the pathophysiology of Lysinuric Protein Intolerance.

SLC7A7 SLC7A6

5.11e-052249231705628
Pubmed

Differential expression of human γ-tubulin isotypes during neuronal development and oxidative stress points to a γ-tubulin-2 prosurvival function.

TUBG2 TUBG1

5.11e-052249228119396
Pubmed

ATM acts downstream of ATR in the DNA damage response signaling of bystander cells.

ATR ATM

5.11e-052249218757420
Pubmed

In Vivo and In Vitro Effects of ATM/ATR Signaling Pathway on Proliferation, Apoptosis, and Radiosensitivity of Nasopharyngeal Carcinoma Cells.

ATR ATM

5.11e-052249228820634
Pubmed

ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations.

ATR ATM

5.11e-052249229279380
Pubmed

ATR regulates fragile site stability.

ATR ATM

5.11e-052249212526805
Pubmed

Ptch2 loss drives myeloproliferation and myeloproliferative neoplasm progression.

PTCH1 PTCH2

5.11e-052249226834157
Pubmed

A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress.

PIK3CG DOCK2

5.11e-052249217325199
Pubmed

KIAA0319 and ROBO1: evidence on association with reading and pleiotropic effects on language and mathematics abilities in developmental dyslexia.

KIAA0319 ROBO1

5.11e-052249224430574
Pubmed

Investigation of switch from ATM to ATR signaling at the sites of DNA damage induced by low and high LET radiation.

ATR ATM

5.11e-052249224238855
Pubmed

Alternative splicing in the Atp7a gene in the Cu deficient mosaic mutation in mice.

ATP7A COL10A1

5.11e-052249219058563
Pubmed

Importin 7 and Nup358 promote nuclear import of the protein component of human telomerase.

RANBP2 IPO7

5.11e-052249224586428
Pubmed

Ataxia-Telangiectasia and RAD3-Related and Ataxia-Telangiectasia-Mutated Proteins in Epithelial Ovarian Carcinoma: Their Expression and Clinical Significance.

ATR ATM

5.11e-052249226124337
Pubmed

Human complement regulators C4b-binding protein and C1 esterase inhibitor interact with a novel outer surface protein of Borrelia recurrentis.

SERPING1 C4BPA

5.11e-052249220532227
Pubmed

ATM regulates ATR chromatin loading in response to DNA double-strand breaks.

ATR ATM

5.11e-052249216461339
InteractionFAM234A interactions

ATR RINT1 XPO6 TBCD IPO7 COG7 XPO4 HEATR1 SLC30A6 SLC16A2 ATM SCN3B IPO11

2.82e-0912623513int:FAM234A
InteractionGPR17 interactions

ATR RINT1 URB1 XPO6 NCAPD2 TBCD LRRC41 COG7 XPO4 HEATR1 SLC30A6 INTS5 LTN1 ATM ATP1A3 IPO11

2.34e-0728323516int:GPR17
InteractionC5AR1 interactions

OMA1 ACP2 RINT1 XPO6 PARL UNC93B1 XPO4 SLC7A6 SLC30A6 SLC7A3 ATM ATP1A3

2.66e-0715423512int:C5AR1
InteractionGPR182 interactions

ATR PLPPR3 URB1 XPO6 PARL NCAPD2 UNC93B1 TBCD HEATR1 SLC7A6 TMEM101 SLC30A6 SFXN5 INTS5 LIPE MROH1 LTN1 ATM ATP1A3 IPO11

4.24e-0745523520int:GPR182
InteractionNPTN interactions

ATR RINT1 XPO6 SEC61B NOC4L TBCD COG7 XPO4 HEATR1 INTS5 MROH1 LTN1 ATM PRNP IPO11

1.01e-0627823515int:NPTN
InteractionOPALIN interactions

ATR XPO6 UNC93B1 XPO4 HEATR1 INTS5 SLC7A3 MROH1 LTN1 ATM ATP1A3 IPO11

6.65e-0620923512int:OPALIN
InteractionMLNR interactions

RINT1 IPO7 XPO4 HEATR1 SLC7A3 ATM IPO11

1.42e-05682357int:MLNR
InteractionCHRM4 interactions

RINT1 XPO6 ABCC10 XPO4 INTS5 TM7SF2 ATP1A3 IPO11

1.43e-05942358int:CHRM4
InteractionVSIG2 interactions

ATR XPO6 IPO7 COG7 XPO4

3.22e-05322355int:VSIG2
InteractionTOP3B interactions

ABCC3 STK36 TMEM8B IREB2 TMCO6 PTCH1 WNK1 BIRC6 CIC TUBG1 SLC52A3 URB1 XPO6 NCAPD2 PYGB CACNA1H HERC2 HERC1 MMP17 SEC23B ABCC10 TBCD PLXNA3 FLII CNOT11 SZT2 HECTD4 CFAP43 SH2B2 TLNRD1 INTS5 C2CD3 MROH1 NEK8 HPS6

4.29e-05147023535int:TOP3B
InteractionENPP1 interactions

STK36 ACP2 PTCH1 FANCE SEC61B HERC2

4.70e-05562356int:ENPP1
InteractionSIGLECL1 interactions

RINT1 XPO6 ITM2B IPO7 XPO4 LTN1 ATP1A3 IPO11

5.42e-051132358int:SIGLECL1
InteractionSGCA interactions

ACP2 TMEM131L ITM2B TMEM59 HEATR1 INTS5 MROH1 ATP1A3

5.42e-051132358int:SGCA
Cytoband11p15.4

DNHD1 IPO7 OR52K1 OR52N4 OR56A5 OR56A3 OR56A4 OR52K2

1.51e-05200249811p15.4
CytobandEnsembl 112 genes in cytogenetic band chr11p15

PIDD1 CDHR5 DNHD1 IPO7 COPB1 OR52K1 OR52N4 OR56A5 OR56A3 OR56A4 OR52K2 CTSD

6.88e-0556424912chr11p15
Cytoband2q12.3

RGPD4 RANBP2 GCC2

1.01e-041724932q12.3
GeneFamilySolute carriers

SLC52A3 SLC9B2 SLC4A9 SLC35D2 SLC7A7 SLC7A6 SLC7A14 SLC4A1 SLC30A6 SLC7A4 SLC7A3 SLC13A1 SLC16A2 SLC18A2 SLC15A5 SLC13A5 SLC35B1

1.19e-0739516417752
GeneFamilyOlfactory receptors, family 56

OR56A5 OR56A3 OR56A4

5.91e-0591643167
GeneFamilyMaestro heat like repeat containing

MROH9 MROH1 MROH2B

1.15e-04111643636
GeneFamilyATP binding cassette subfamily C

ABCC3 ABCC10 ABCC1

1.96e-04131643807
GeneFamilyGlycogen phosphorylases

PYGB PYGM

2.44e-0431642437
GeneFamilyExportins

XPO6 XPO4

1.67e-0371642547
GeneFamilyATPase Na+/K+ transporting subunits

ATP1A3 ATP1A4

1.67e-03716421208
GeneFamilyTransmembrane channel likes

TMC3 TMC2

2.21e-03816421135
GeneFamilyAdenylate cyclases|Deafness associated genes

ADCY10 ADCY4

3.51e-0310164253
GeneFamilyAdenosine receptors|V-set domain containing

TIMD4 ESAM CD8A CD300LG SCN3B TREML2

3.75e-031631646590
ToppCellSubstantia_nigra-Hematopoietic|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ABCC3 PIK3CG C3AR1 DOCK2 TBXAS1 MRC1 TIMD4 PTPN18 CTSD TOP2A NCKAP1L

1.80e-091602491119d71d02f06f34eff37d268a78e5eed34da4ca44
ToppCellPosterior_cortex-Hematopoietic|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ABCC3 PIK3CG C3AR1 UNC93B1 DOCK2 TBXAS1 SLC7A7 PTPN18 CTSD NCKAP1L

6.79e-0817824910ea9e4f461dda34c0ebc707d7dbefc7a49ce5bb55
ToppCellfrontal_cortex-Non-neuronal-macrophage-Macrophage|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ABCC3 PIK3CG C3AR1 UNC93B1 DOCK2 TBXAS1 MRC1 PTPN18 NCKAP1L

3.59e-071632499cbe9b4c4b2e42e9f92a57ed66758af93434db5bb
ToppCellfrontal_cortex-Non-neuronal-macrophage|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ABCC3 PIK3CG C3AR1 UNC93B1 DOCK2 TBXAS1 MRC1 PTPN18 NCKAP1L

3.59e-071632499b89f586b444f90047c8ce407f53847fd1ee7cca3
ToppCellThalamus-Hematopoietic|Thalamus / BrainAtlas - Mouse McCarroll V32

ABCC3 PIK3CG C3AR1 DOCK2 TBXAS1 MRC1 PTPN18 CTSD NCKAP1L

4.19e-07166249976d60ac7ac5d1eaf530f0c741d9c48e0bd58396b
ToppCellfacs-Heart-LV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 PIK3CG C3AR1 DOCK2 TBXAS1 MRC1 PTPN18 ATP1A3 NCKAP1L

5.12e-07170249960041b2e57e958f300a5bc76851705c8baf297c2
ToppCellfacs-Heart-LV-18m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 PIK3CG C3AR1 DOCK2 TBXAS1 MRC1 PTPN18 ATP1A3 NCKAP1L

5.12e-0717024994eaa22040e475100061475123aefa32b56481464
ToppCelldroplet-Heart-nan-18m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 PIK3CG C3AR1 UNC93B1 DOCK2 TBXAS1 MRC1 PTPN18 NCKAP1L

5.12e-0717024997077eaf68ac859f63d6581d26a95c20d6a04bd28
ToppCellfacs-Heart-LV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 PIK3CG C3AR1 DOCK2 TBXAS1 MRC1 PTPN18 ATP1A3 NCKAP1L

5.12e-071702499793dde64f5517538b66de5f461a445c4ad6dd7b3
ToppCelldroplet-Heart-nan-18m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 PIK3CG C3AR1 UNC93B1 DOCK2 TBXAS1 MRC1 PTPN18 NCKAP1L

5.38e-07171249979b806194df645cccd357520eb6801ab1e93b3c5
ToppCelldroplet-Heart-nan-18m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 PIK3CG C3AR1 UNC93B1 DOCK2 TBXAS1 MRC1 PTPN18 NCKAP1L

5.38e-0717124992594ba8236a69461d9786ffcd882c39d0c9d5788
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCC3 PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 PTPN18 CTSD NCKAP1L

5.65e-071722499714172f31abd0d25261df6115ec6a9df491fa14b
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CG C3AR1 UNC93B1 DOCK2 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

5.93e-0717324991ea8b8b89611bebf6acb700fb04a7d38720775a9
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCC3 PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 PTPN18 CTSD NCKAP1L

6.23e-0717424990a8fa44604be19fbac722ebc6d1cd72b71be7022
ToppCelldroplet-Heart-HEART-1m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 C3AR1 UNC93B1 DOCK2 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

6.53e-07175249943b9cfd7c47d57244565c641e57f3256b5900804
ToppCelldroplet-Heart-HEART-1m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 C3AR1 UNC93B1 DOCK2 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

6.53e-071752499a2fed97cf8d28f9936fe791e5e8c43d2430330c9
ToppCelldroplet-Heart-HEART-1m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 C3AR1 UNC93B1 DOCK2 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

6.85e-0717624991df640f88667e2dad30e65279d6d33bba75024c1
ToppCellprimary_visual_cortex-Non-neuronal-macrophage-Macrophage-PVM_Mrc1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PIK3CG C3AR1 UNC93B1 DOCK2 TBXAS1 MRC1 TIMD4 PTPN18

7.14e-0713024983a0846b74ba34bd0e2a05b4f1f39f3940df93780
ToppCellPosterior_cortex-Neuronal|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

KIAA0319 HERC1 PAQR9 SLITRK3 GCC2 TCF25 ATP1A3 UNC13A UNC80

1.48e-061932499b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC52A3 SLC4A9 PNP TMEM116 TMEM59 TMEM101 SLC4A1 ATP6V0A4 CTSD

1.68e-0619624996ee8dcc5cd643747e20d23b9556c17f7c102b19c
ToppCellwk_08-11-Hematologic-Myeloid-SPP1+_Mac|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PIK3CG C3AR1 DOCK2 TBXAS1 MRC1 TIMD4 SLC7A7 CTSD NCKAP1L

1.90e-061992499d94cf750599366061066074e8007d707adf6fc5a
ToppCellfrontal_cortex-Non-neuronal-macrophage-Macrophage-PVM_Mrc1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

1.90e-061482498d3ea907f8f408e9bb97ed223a3089e403e35f911
ToppCellE12.5-Hematopoietic|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 PTPN18 SLC4A1 NCKAP1L

2.95e-061572498344351c7534440532c6cd4a95782ac90b10d45f3
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_4|368C / Donor, Lineage, Cell class and subclass (all cells)

C3AR1 TMEM236 OTOA MRC1 TIMD4 PAPSS1 CTSD NCKAP1L

3.10e-061582498f9cfb110342be3c91aba9914805332f22ba89101
ToppCellFrontal_cortex-Hematopoietic-MICROGLIA|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ADGRG5 ABCC3 QRICH2 PIK3CG C3AR1 DOCK2 TBXAS1 NCKAP1L

3.25e-06159249841d2c1e71f6983156f8cc8ec5f69e025e5700f46
ToppCellE12.5-Hematopoietic-Immune-immune_cell_unspecified|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 SLC7A7 PTPN18 NCKAP1L

3.40e-0616024985a4a5a50dfdf6af9406e4f685712f7fe390a02f3
ToppCellE12.5-Hematopoietic-Immune|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 SLC7A7 PTPN18 NCKAP1L

3.40e-061602498cd59830a524c14a1f591c5c615b55510e4104e5b
ToppCellFrontal_cortex-Hematopoietic|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCC3 PIK3CG C3AR1 DOCK2 TBXAS1 MRC1 PTPN18 NCKAP1L

3.40e-06160249870ffbe61cfd729519b23569a43d929b117ab8d5e
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1H GPR143 RFX4 POSTN SLC7A3 ATP1A3 SCN3B

3.85e-061152497c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1H GPR143 RFX4 POSTN SLC7A3 ATP1A3 SCN3B

3.85e-061152497ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1H GPR143 RFX4 POSTN SLC7A3 ATP1A3 SCN3B

3.85e-0611524977a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCelldroplet-Bladder-nan-3m-Hematologic-leukocyte|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3AR1 UNC93B1 DOCK2 TBXAS1 MRC1 PTPN18 ATP1A3 NCKAP1L

3.90e-0616324982f32a9ab0230fdca98ffa7fd59397301d50e4f30
ToppCelldroplet-Bladder-nan-3m-Hematologic|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3AR1 UNC93B1 DOCK2 TBXAS1 MRC1 PTPN18 ATP1A3 NCKAP1L

3.90e-0616324986c2967dee563295febe2adabf503d095cb911ccf
ToppCellE17.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

C3AR1 UNC93B1 TBXAS1 MRC1 SLC7A7 PTPN18 CTSD NCKAP1L

4.08e-0616424984e9de41ea10ce3233c09e144bfc0453c0ae79fd3
ToppCelldroplet-Heart-nan-3m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

4.08e-061642498df9fe446c1a43100048e11c01bf009bec3414dcf
ToppCellfacs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIK3CG UNC93B1 DOCK2 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

4.08e-0616424985ca7b69684a8bb12dd0b45e7ad94e30d16ed01ce
ToppCellE17.5-Endothelial-lymphatic_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

C3AR1 UNC93B1 TBXAS1 MRC1 SLC7A7 PTPN18 CTSD NCKAP1L

4.08e-0616424986f4914b0ac282b4b9f6111930a82515178c1bc80
ToppCellE15.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

C3AR1 UNC93B1 TBXAS1 MRC1 SLC7A7 PTPN18 CTSD NCKAP1L

4.27e-0616524988d3d5860a4785c4908160ae5fcb421ee80bd78ce
ToppCellE15.5-Endothelial-lymphatic_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

C3AR1 UNC93B1 TBXAS1 MRC1 SLC7A7 PTPN18 CTSD NCKAP1L

4.27e-06165249817ee6f269ed8d378465cf00ca59d48d8b106808e
ToppCelldroplet-Heart-nan-3m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

4.67e-06167249847447bcf184b1ad24ef17e135199fe7cd1d73c02
ToppCelldroplet-Heart-4Chambers-21m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 C3AR1 UNC93B1 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

4.88e-0616824988ff4666fdda562913060b1cfa2dfab34e0606794
ToppCellfacs-Heart-RV-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

4.88e-061682498c1a5f4f4d32a1f8583048db709a7037cc9357ad8
ToppCelldroplet-Heart-nan-3m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

4.88e-061682498a4eebc78babb9b5ef33065b0642793820195a613
ToppCellfacs-Heart-RV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

4.88e-0616824988ee57814c7e9d45444f48b6b269c4d535bc4d5e1
ToppCellfacs-Heart-RV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

4.88e-061682498a405f0de70293f68b4e000c1fc8a9ad33d56539a
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 C3AR1 UNC93B1 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

5.10e-0616924983296305dc4fa40c466dab56aab4eac302ae3d7f7
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

URB1 PIK3CG ABCC10 MRC1 HEATR1 UHMK1 CTSD NCKAP1L

5.10e-061692498305cedbd97059029d7d2a248a8a4b6cfe281aa54
ToppCellPND01-03-samps-Mesenchymal-Pericyte-pericyte_F|PND01-03-samps / Age Group, Lineage, Cell class and subclass

KATNB1 MYOZ2 TMCO6 KLHL8 MMP17 SLC7A6 POSTN CD300LG

5.32e-06170249871718dcebd48105994c313bb55babc70301170a0
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 PTPN18 CTSD NCKAP1L

5.32e-0617024986ec0cf055ae55e9fac147f7989c47f83ab07270c
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 C3AR1 UNC93B1 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

5.32e-0617024988ea5ab8c890eb91c5b0aae3996e1d1c61c97f0c7
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 PTPN18 CTSD NCKAP1L

5.80e-061722498c96bd3407911df3e3e6d7a3dba786b11814b9598
ToppCellPND07-28-samps-Myeloid-Macrophage-CD163+_Macrophage|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ABCC3 C3AR1 UNC93B1 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

5.80e-0617224989a659442dc41bd2a4361a7e38a7ee37a39781667
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C3AR1 UNC93B1 ITM2B TBXAS1 MRC1 PTPN18 CTSD NCKAP1L

5.80e-061722498f0e767a20d93e546ce278db67dbd779cc68af533
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAX1 SLC52A3 PIK3CG SZT2 HEATR1 TPSD1 SLC18A2 CDC34

5.80e-061722498028a5441242b2cc760cafc1822120180619c63ae
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAX1 SLC52A3 PIK3CG SZT2 HEATR1 TPSD1 SLC18A2 CDC34

5.80e-0617224989fc70b1a143a8ec910336c23b761d908bb6aecb2
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAX1 SLC52A3 PIK3CG SZT2 HEATR1 TPSD1 SLC18A2 CDC34

5.80e-06172249813d7117f92a92d77d6b4335ed800c585dc8b4511
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAX1 SLC52A3 PIK3CG SZT2 HEATR1 TPSD1 SLC18A2 CDC34

5.80e-0617224983d83b2f03ad3af4dae3fe6cc0a0ef356872ca94f
ToppCell3'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAX1 SLC52A3 PIK3CG SZT2 HEATR1 TPSD1 SLC18A2 CDC34

5.80e-061722498a3d431aed12c1192e8dca1dc85b8340fb7354f8d
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage|368C / Donor, Lineage, Cell class and subclass (all cells)

ABCC3 C3AR1 UNC93B1 MRC1 TIMD4 SLC7A7 CTSD NCKAP1L

6.06e-061732498bba8265a58f8f5659dc7b9da2fe27b15033fce34
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CG C3AR1 DOCK2 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

6.06e-061732498a0e4d25db186b9f7ff819abc0db68ad58c92ba3b
ToppCellfacs-Heart-LV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 PTPN18 NCKAP1L

6.32e-06174249854166a0faf748cccb6406c2c268e1e6e21caf6d0
ToppCellfacs-Heart-LA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

6.32e-0617424981802a52552256d1e25d8b328ba62dcfe41671900
ToppCellfacs-Heart-LV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 PTPN18 NCKAP1L

6.32e-061742498dc8a238ec1d954bec0f8eb67c04a61734c96f5b5
ToppCellfacs-Heart-LA-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

6.32e-06174249830c083fe4711735e83dccfd00fcd746ae673d353
ToppCellfacs-Heart-LA-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 TIMD4 PTPN18 NCKAP1L

6.32e-06174249846d19c1144fff19be682b7ba59d4c3e014f79e15
ToppCellfacs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIK3CG C3AR1 UNC93B1 DOCK2 TBXAS1 MRC1 PTPN18 NCKAP1L

6.32e-061742498d67fc8e30cc67fff8f7fdeaccb409d12ca0992c1
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C3AR1 UNC93B1 ITM2B TBXAS1 MRC1 PTPN18 CTSD NCKAP1L

6.32e-061742498f520b79d277e286c9bb5d091e6c94e7ec7e46699
ToppCellfacs-Heart-LV-3m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 PIK3CG C3AR1 UNC93B1 TBXAS1 MRC1 PTPN18 NCKAP1L

6.59e-0617524985d106ef542b97f97aeb19179e3f72963ead1e82a
ToppCellfacs-Trachea-3m-Hematologic-myeloid|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIK3CG C3AR1 UNC93B1 DOCK2 TBXAS1 MRC1 PTPN18 NCKAP1L

6.59e-06175249822fd7d9b4d403cc8061316855f78bad0eb705ce9
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OTOA ADCY4 F2RL3 ESAM SELENON LIPE SLC13A5 CD300LG

7.46e-061782498360d7a987f91d6d721487a921824057ec31a7332
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

C3AR1 UNC93B1 DOCK2 TBXAS1 SLC7A7 PTPN18 CTSD NCKAP1L

7.78e-0617924985122fc794509492afde4af8b1b76d51e3070ef05
ToppCellwk_20-22-Hematologic-Myeloid-pDC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADGRG5 TMEM8B CDHR5 SEC61B UNC93B1 SLC18A2 NEK8 GUCY2D

8.43e-06181249860607c5ff6d5b1cb416adc034491dca31c41e988
ToppCellwk_20-22-Hematologic-Meg-ery-Definitive_erythroblast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADCY10 CD55 WNK1 HERC1 TBCEL PNP HECTD4 SLC4A1

8.78e-0618224980c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCell5'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRG5 PIK3CG C3AR1 UNC93B1 DOCK2 MRC1 SLC7A6 NCKAP1L

1.11e-05188249872a1ee136d77c77e44793a512f60b5f7815a073a
ToppCell5'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRG5 PIK3CG C3AR1 UNC93B1 DOCK2 MRC1 SLC7A6 NCKAP1L

1.11e-051882498ecbba19eebba21b986caa99de78ea4245fde3600
ToppCellnormal_Lung-MAST_cells|normal_Lung / Location, Cell class and cell subclass

LAX1 ZSWIM4 HS3ST1 KIAA1549 TPSD1 SLC18A2 ELF1 ATP1A4

1.16e-051892498f09e387dc0626536050cd537dda212471a7267c4
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAX1 DOCK2 TBXAS1 MRC1 ATP10A TPSD1 SLC18A2 NCKAP1L

1.16e-0518924987ccea2df93bb4b37417bbc8f6c85a61ece95211a
ToppCellnormal_Lung-MAST_cells-MAST|normal_Lung / Location, Cell class and cell subclass

LAX1 ZSWIM4 HS3ST1 KIAA1549 TPSD1 SLC18A2 ELF1 ATP1A4

1.16e-051892498fd053209034fca6eaefe0e5ad024ac4548a100c9
ToppCellfacs-Marrow-KLS-18m-Hematologic-MPP_Fraction_A_+_HSC|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIPK1B PYGM TBXAS1 F2RL3 ESAM SLC7A4 SLC18A2 IPO11

1.20e-05190249896a9756cad5468a12591021e6d661ed269b5b3d9
ToppCellfacs-Pancreas-Endocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGA SERPING1 SEC61B KCNK16 SLC7A14 PAM UNC80 PRNP

1.25e-051912498b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGA SERPING1 SEC61B KCNK16 SLC7A14 PAM UNC80 PRNP

1.25e-051912498657297cd19d05a7e7bb74fc3a086fbd95f47aae4
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A9 TIMD4 TMEM116 TMEM101 SLC4A1 ATP6V0A4 UHMK1 CTSD

1.30e-0519224984842a55650fc4687c9184d498a8c05c259d15186
ToppCellPCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_neutrophils_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADGRG5 PIK3CG C3AR1 TMEM236 DOCK2 MRC1 TIMD4 NCKAP1L

1.34e-051932498c9e3fefa8d68d0e2b954f85ce37813185ff98d84
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DIPK1B QRICH2 ADCY4 NPR3 KIAA1549 ESAM POSTN CD300LG

1.40e-05194249868004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCellFrontal_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCC3 PIK3CG C3AR1 DOCK2 TBXAS1 MRC1 NCKAP1L

1.40e-0514024978db98a17a4d4b42dbfc75e9cdaa22275fed4f2f0
ToppCellFrontal_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCC3 PIK3CG C3AR1 DOCK2 TBXAS1 MRC1 NCKAP1L

1.40e-0514024972c04fa782aa076e4be8a2781aa04231180bd69bd
ToppCellFrontal_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Fos_(Microglia.C1qb.Tmem119-Fos)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCC3 PIK3CG C3AR1 DOCK2 TBXAS1 MRC1 NCKAP1L

1.40e-051402497a9389a6e55d02d5037868c9ecce48b5e8d7c2902
ToppCellFrontal_cortex-Hematopoietic-MICROGLIA-MI1(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Fos_(Microglia.C1qb.Tmem119-Fos)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ABCC3 PIK3CG C3AR1 DOCK2 TBXAS1 MRC1 NCKAP1L

1.40e-05140249722098203361f61b9f0ce9f0f2d1369d8bb1379a8
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

CD55 ARHGEF7 HS3ST1 MRC1 ADCY4 ESAM CD300LG IPO11

1.45e-0519524986b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCellNon-neuronal-Postmitotic-Microglia-Microglia-39|World / Primary Cells by Cluster

MYOZ2 C3AR1 ITM2B TBXAS1 SLC7A7 ELF1 CTSD NCKAP1L

1.45e-05195249894e03ea4084d166ccc32bc34f26ff8709d312dfb
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Striatum / BrainAtlas - Mouse McCarroll V32

LAX1 SLC52A3 IGSF23 F2RL3 GPR143 GUCY2D

1.47e-059424969d1dfd534871da30bc25a42e36bed9826f6127d8
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Striatum / BrainAtlas - Mouse McCarroll V32

LAX1 SLC52A3 IGSF23 F2RL3 GPR143 GUCY2D

1.47e-05942496858dda192747e71533736247bc9e135f763a8860
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Striatum / BrainAtlas - Mouse McCarroll V32

LAX1 SLC52A3 IGSF23 F2RL3 GPR143 GUCY2D

1.47e-05942496901c4908d27a06c81853a02042cd331549e0e27d
ToppCellP03-Hematopoietic|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADGRG5 DOCK2 PAQR9 SLC4A1 ATP1A3 TREML2 NCKAP1L

1.47e-0514124974a856521520ea73291f4730fe94c5de88c2b6f0c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WNK1 SLC52A3 SLC4A9 TMEM59 TMEM101 SLC4A1 ATP6V0A4 CTSD

1.50e-051962498cd8c22c6f52f068a33525723108d6b5b23fe822d
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYOZ2 SERPING1 C3AR1 UNC93B1 ITM2B TBXAS1 SLC7A7 CTSD

1.56e-0519724980a22686d586c0334a2fd872a28e26b75693234cf
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_Resident_macrophages|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ACP2 SERPING1 C3AR1 ITM2B MRC1 TMEM59 SLC7A7 CTSD

1.56e-0519724988736f1d446db3eb28a99997a9a683ded8e18e4c6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CD55 C3AR1 ITM2B DOCK2 TBXAS1 SLC7A7 ELF1 CTSD

1.56e-051972498e27577a1fa553986044512f52c252a587f864510
ToppCellNon-neuronal-Postmitotic-Microglia-Microglia|World / Primary Cells by Cluster

MYOZ2 C3AR1 ITM2B TBXAS1 SLC7A7 ELF1 CTSD NCKAP1L

1.62e-05198249876bcdd96e311fe80504e32e9b5fef0b6510c54b6
ToppCell10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

LAX1 C3AR1 HS3ST1 ABCC1 PAPSS1 TPSD1 SLC18A2 ELF1

1.62e-051982498a1247a5efd92f95c6227c0e71dc8a0427eb54b7f
DiseaseSKIN/HAIR/EYE PIGMENTATION, VARIATION IN, 1

HERC2 OCA2

6.26e-0522342227220
Diseaselymphoma (implicated_via_orthology)

UBIAD1 ATM

6.26e-0522342DOID:0060058 (implicated_via_orthology)
Diseaseataxia telangiectasia (implicated_via_orthology)

ATR ATM

6.26e-0522342DOID:12704 (implicated_via_orthology)
DiseaseSKIN/HAIR/EYE PIGMENTATION 1, BLUE/NONBLUE EYES

HERC2 OCA2

6.26e-0522342cv:C1856895
DiseaseKohlschutter Tonz syndrome

ROGDI SLC13A5

6.26e-0522342C0406740
Diseasecomplex cortical dysplasia with other brain malformations 4 (implicated_via_orthology)

TUBG2 TUBG1

6.26e-0522342DOID:0090138 (implicated_via_orthology)
Diseasebasal cell carcinoma (is_implicated_in)

PTCH1 OCA2 PTCH2

1.03e-04122343DOID:2513 (is_implicated_in)
Diseaseiron deficiency anemia (biomarker_via_orthology)

ATP7A IREB2 SLC4A1

1.33e-04132343DOID:11758 (biomarker_via_orthology)
DiseaseQuadriparesis

ITM2B TBCD

1.87e-0432342C0270790
Diseaseanemia (implicated_via_orthology)

IREB2 SLC4A9 SLC4A1

2.09e-04152343DOID:2355 (implicated_via_orthology)
Diseasesuntan, skin pigmentation

HERC2 OCA2

3.72e-0442342EFO_0003784, EFO_0004279
Diseaserenal tubular acidosis (is_implicated_in)

SLC4A1 ATP6V0A4

3.72e-0442342DOID:14219 (is_implicated_in)
DiseaseBASAL CELL CARCINOMA, SUSCEPTIBILITY TO, 1

PTCH1 PTCH2

3.72e-0442342605462
DiseaseBasal cell carcinoma, susceptibility to, 1

PTCH1 PTCH2

3.72e-0442342cv:C2751544
DiseaseOculo-dento-digital syndrome

PTCH1 PTCH2

3.72e-0442342C0812437
Diseaseage-related macular degeneration, cataract, glaucoma

HERC2 PCDHGA5

3.72e-0442342EFO_0001365, MONDO_0005041, MONDO_0005129
DiseaseGastrointestinal Stromal Sarcoma

STK36 PTCH1 C2CD3 PTCH2

5.26e-04472344C3179349
DiseaseN-acetylglucosaminylasparagine measurement

UNC93A AGA

6.16e-0452342EFO_0800151
DiseaseDistal Renal Tubular Acidosis

SLC4A1 ATP6V0A4

6.16e-0452342C1704380
DiseaseKohlschutter-Tonz syndrome (implicated_via_orthology)

SLC13A1 SLC13A5

6.16e-0452342DOID:0111668 (implicated_via_orthology)
DiseaseBasal Cell Nevus Syndrome

PTCH1 PTCH2

6.16e-0452342C0004779
DiseaseMedulloblastoma

PTCH1 PIK3CG PTCH2 ATM

6.67e-04502344C0025149
DiseaseGastrointestinal Stromal Tumors

STK36 PTCH1 C2CD3 PTCH2

6.67e-04502344C0238198
Diseaseage-related macular degeneration

MBL2 HERC2 HS3ST1 COL10A1 CDH13

7.26e-04892345EFO_0001365
Diseasefamilial hemiplegic migraine (implicated_via_orthology)

ATP1A3 ATP1A4

1.28e-0372342DOID:0060178 (implicated_via_orthology)
Diseasearteriosclerosis (implicated_via_orthology)

TBXAS1 LIPE

1.28e-0372342DOID:2349 (implicated_via_orthology)
Diseaseaflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)

GGT3P GGT2P

1.28e-0372342DOID:5022 (biomarker_via_orthology)
Diseasealcohol-related neurodevelopmental disorder (implicated_via_orthology)

SLC13A1 SLC13A5

1.70e-0382342DOID:0050667 (implicated_via_orthology)
Diseasealcohol dependence (biomarker_via_orthology)

GGT3P GGT2P

1.70e-0382342DOID:0050741 (biomarker_via_orthology)
Diseaserenal tubular acidosis (implicated_via_orthology)

SLC4A1 ATP6V0A4

1.70e-0382342DOID:14219 (implicated_via_orthology)
DiseaseVentricular Dysfunction, Left

NPPB ATM ATP1A3

1.71e-03302343C0242698
Diseasemean reticulocyte volume

ADGRG5 CRISP2 ATR TMEM131L ABCC10 PAQR9 DPAGT1 ABCC1 TIMD4 PCDHGA5 E2F4 SLC4A1 ELF1 ATM IPO11

1.91e-0379923415EFO_0010701
Diseaseepilepsy (implicated_via_orthology)

KCNK16 SLC13A1 SLC13A5 ATP1A3 ATP1A4 UNC13A

1.97e-031632346DOID:1826 (implicated_via_orthology)
Diseaseneuroimaging measurement, brain volume measurement

ATR MBL2 PTCH1 PYGB MRC1 RFX4 ROBO1 CATSPERB

2.12e-032862348EFO_0004346, EFO_0006930
Diseasetryptase beta-2 measurement

CACNA1H TPSD1

2.17e-0392342EFO_0008306
DiseaseMicrolissencephaly

KATNB1 TUBG1 TBCD

2.25e-03332343C1956147
DiseaseBrain hemorrhage

UBIAD1 ITM2B

2.70e-03102342C0553692
Diseasehair colour measurement, eye colour measurement, skin pigmentation measurement

HERC2 OCA2

2.70e-03102342EFO_0007009, EFO_0007822, EFO_0009764
Diseasehypertension (is_implicated_in)

WNK1 ADRB3 NPPB NPR3 LIPE

2.83e-031212345DOID:10763 (is_implicated_in)
Diseaseage at menopause

BIRC6 CHUK PIK3CG PARL LRRC41 PNP IPO7 TCF25

2.97e-033022348EFO_0004704
Diseasepneumococcal bacteremia

DOCK2 LAMB4

3.29e-03112342EFO_1001925
Diseasepigmentation disease (is_implicated_in)

HERC2 OCA2

3.29e-03112342DOID:10123 (is_implicated_in)
Diseasedegenerative disc disease (biomarker_via_orthology)

COL10A1 POSTN

3.29e-03112342DOID:90 (biomarker_via_orthology)
Diseasecups of coffee per day measurement

HECTD4 ATP1A3 ATP1A4

3.92e-03402343EFO_0006782
Diseasepsychological resilience measurement

SLC7A7 SLC15A5

3.92e-03122342EFO_0009945
Diseasenervous system disease (implicated_via_orthology)

ATP1A3 ATP1A4

3.92e-03122342DOID:863 (implicated_via_orthology)
Diseasebrain disease (is_implicated_in)

UNC93B1 RANBP2

3.92e-03122342DOID:936 (is_implicated_in)
Diseaseacute myeloid leukemia (implicated_via_orthology)

SF3B1 TOP2A

3.92e-03122342DOID:9119 (implicated_via_orthology)
Diseaseventricular enlargement measurement

ABCC1 CATSPERB

4.61e-03132342EFO_0010570
Diseasetoxic shock syndrome (is_implicated_in)

MBL2 SERPING1

4.61e-03132342DOID:14115 (is_implicated_in)
Diseaseglutaroyl carnitine measurement

ABCC1 SLC7A6

4.61e-03132342EFO_0021005
DiseaseAutism Spectrum Disorders

CIC ROGDI SLC16A2 UNC80

4.73e-03852344C1510586
DiseaseChildhood Medulloblastoma

PTCH1 PIK3CG PTCH2

4.81e-03432343C0278510
DiseaseMelanotic medulloblastoma

PTCH1 PIK3CG PTCH2

4.81e-03432343C1275668
DiseaseMedullomyoblastoma

PTCH1 PIK3CG PTCH2

4.81e-03432343C0205833
DiseaseDesmoplastic Medulloblastoma

PTCH1 PIK3CG PTCH2

4.81e-03432343C0751291
DiseaseAdult Medulloblastoma

PTCH1 PIK3CG PTCH2

4.81e-03432343C0278876
Diseaseskin pigmentation measurement

UNC93A PTCH1 HERC2 OCA2 TCF25

4.81e-031372345EFO_0007009
DiseaseGlioma

ATR CIC ATM TOP2A

5.13e-03872344C0017638
DiseaseMalformations of Cortical Development

TUBG1 TBCD

5.35e-03142342C1955869
DiseaseCortical Dysplasia

TUBG1 TBCD

5.35e-03142342C0431380
Diseasediabetic retinopathy (biomarker_via_orthology)

PIK3CG NPR3 ROBO1

5.47e-03452343DOID:8947 (biomarker_via_orthology)
DiseaseMalignant neoplasm of breast

WNK1 CIC HERC2 ANAPC5 FOXP3 RCE1 TBXAS1 DPAGT1 ABCC1 PIGS OCA2 SLC7A7 ZNF546 LIPE ROBO1 ATM TOP2A

5.58e-03107423417C0006142
Diseaseaspartate aminotransferase measurement

PTCH1 BIRC6 UBIAD1 KLHL8 TMEM236 PNP MRC1 FBLN7 HECTD4 PTPN18 TMX2 ROBO1 ELF1 CTSD PRNP

5.96e-0390423415EFO_0004736
Diseaseemployment status

MBL2 IPO11

6.14e-03152342EFO_0005241
DiseaseAlzheimer disease, dementia, family history of Alzheimer’s disease

RFX4 ROBO1 TREML2

6.55e-03482343EFO_0009268, MONDO_0001627, MONDO_0004975
DiseaseSchizoaffective disorder-bipolar type

PTCH1 SCN3B

6.98e-03162342EFO_0009965
Diseasemean arterial pressure, alcohol drinking

TRIM36 NPPB NPR3 HECTD4

7.79e-03982344EFO_0004329, EFO_0006340
DiseaseBenign neoplasm of stomach

ATR ATM

7.87e-03172342C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ATR ATM

7.87e-03172342C0496905
Diseaseglutarylcarnitine (C5-DC) measurement

ABCC1 SLC7A6

7.87e-03172342EFO_0800030
DiseaseCarcinoma in situ of stomach

ATR ATM

7.87e-03172342C0154060
DiseaseLimb Deformities, Congenital

CHUK SALL4

7.87e-03172342C0206762

Protein segments in the cluster

PeptideGeneStartEntry
RQLLLTQMIPPDFSL

PTPN18

246

Q99952
VLPPLTDQTMIGNLL

UNC13A

1391

Q9UPW8
NFEILSLMRLCPIIP

TDRD1

581

Q9BXT4
MLFGIRILVNTPSPL

nan

1

Q9HAA7
LFISGLSDQLIPPVM

ABHD13

261

Q7L211
PILFQMTLIAALLPA

C4BPA

31

P04003
IIKSTPAAIIFPLML

SLC4A9

901

Q96Q91
LEMFTLPTLLPQVST

CFAP43

551

Q8NDM7
FILQAIPSSQPMTVL

ELF1

466

P32519
VLLIQTLGALMPSLP

COG7

281

P83436
MPITADLVAPILRFL

BIRC6

3676

Q9NR09
PLPAEMTLAQLLTLL

BIRC6

3976

Q9NR09
AIASCAAMVPLLLPL

BIRC6

4401

Q9NR09
RMLEIPLLTVFVGNP

CATSPERB

756

Q9H7T0
GLSILMEPILSRIPL

SLC4A1

771

P02730
MEPILSRIPLAVLFG

SLC4A1

776

P02730
LVLSSGMLVPELAIP

GSDMD

356

P57764
MAGRVPSLLVLLVFP

PAM

1

P19021
IQMLVTNRPPALAIT

ADCY4

601

Q8NFM4
MLRELPKSQPFTLRL

GIPC3

176

Q8TF64
LLLFPNVLLMLSASP

ARHGEF7

501

Q14155
QVFPSLSLIPLTQML

AMTN

46

Q6UX39
LSLIPLTQMLTLGPD

AMTN

51

Q6UX39
MALPVTALLLPLALL

CD8A

1

P01732
PLIPALSIVLNICLM

SLC7A4

546

O43246
TPQSLLATLMPLPEL

DNHD1

4356

Q96M86
IRTLPIFIIMSLCPF

ADCY10

661

Q96PN6
MGLLVVPPAATLALT

ADRB3

86

P13945
MQPRTPLVLCVLLSQ

CDH13

1

P55290
VARSVPSPMTFLLLV

CDHR5

311

Q9HBB8
LIVASPKMLLRLPAA

DHTKD1

761

Q96HY7
PKMLLRLPAAVSTLQ

DHTKD1

766

Q96HY7
DLPSLPALVGQVLLM

DIPK1B

166

Q5VUD6
TISLLIQPMALAVRL

MT-ATP6

146

P00846
PPVILSMVILSLTFL

C3AR1

21

Q16581
MALLPVLFLVTVLLP

CRISP2

1

P16562
LTCLMTPVAALLPRL

ATP10A

1276

O60312
MPSLLVLTFSPCVLL

NPR3

1

P17342
LVVIAQPSSEMPLLT

ATP7A

451

Q04656
FVLMLLSLTYRPLLP

SLC16A2

271

P36021
PLGRITMELFSNIVP

RANBP2

3076

P49792
NIPFTATMIPVLLNL

OCA2

741

Q04671
LMIIVPPLSLGLQLE

OR6C2

151

Q9NZP2
FLLAQMVKRTIPPEL

QRICH2

1066

Q9H0J4
VLMPTVLQALPDSLT

RFX4

266

Q33E94
TEAVMLGLPVSLTLP

IREB2

301

P48200
VPENIPVGTRLLMLT

PCDHGA5

251

Q9Y5G8
LLSILIRFISNPMAP

ABCC3

331

O15438
LQPSSELPLNTIMLL

KIAA1549

696

Q9HCM3
ALSPPAALMSLLSIQ

LTN1

1431

O94822
VIARNAFVSLPVPML

OR56A4

151

Q8NGH8
AFVSLPVPMLSARLR

OR56A4

156

Q8NGH8
SPTIALPMLLQALAL

ANAPC5

596

Q9UJX4
EVSRLSMPPFLLAAL

OTOA

626

Q7RTW8
MVPSSPRALFLLLLI

FBLN7

1

Q53RD9
MPSARLSGPVLALIL

GGT3P

276

A6NGU5
LALVRMLILPLNNFP

ABCC10

541

Q5T3U5
ILLPEIVMISTLPFC

OR6K3

171

Q8NGY3
MAQSRVLLLLLLLPP

PODN

1

Q7Z5L7
TPLRERFLQPLMALL

OGFOD2

191

Q6N063
HIIVANIYLLLPPTM

OR52N4

276

Q8NGI2
TVVIPMLNPLIYSLR

OR5B21

276

A6NL26
DLTALFLPRQPPMSL

FLII

876

Q13045
LIASTPALRTPMFVL

GPR6

96

P46095
PALRTPMFVLVGSLA

GPR6

101

P46095
PRNGLLMPLLSVIFL

MAGEB4

196

O15481
PSQLQLPTLPLVMVA

FOXP3

66

Q9BZS1
TSIVMPPRNLLELLI

ITM2B

171

Q9Y287
RQFMLGPAILISPVL

MGAM2

1606

Q2M2H8
RLLTQMLPPSVAEAL

GUCY2D

851

Q02846
EGMARVVPVPLLSLF

HERC2

4651

O95714
LTLGTLVILIFPPMV

KCNK16

176

Q96T55
TSPILPLPDVMLLAR

GARIN4

76

Q8IYT1
TIPLAMAILRLDTNP

HERC3

526

Q15034
VFMLLTLEPLLARSP

HERC3

686

Q15034
LNMTSAKIISFLLPP

CHUK

316

O15111
MPDVFTPLKQLILLS

LRRC53

196

A6NM62
ITPELLRIFQNMSPL

IPO11

681

Q9UI26
PLRNLLFRLMDSTVP

HERC1

821

Q15751
LQRFLPLITDMLAAP

KATNB1

586

Q9BVA0
MTVARPSVPAALPLL

CD55

1

P08174
TLFKAMPLQPSILRE

POLD2

96

P49005
ELPMPLLINLIVSLL

DPAGT1

6

Q9H3H5
LLLPTAASLPLLMVY

DPAGT1

126

Q9H3H5
GIFPAALLPLLLTMI

RCE1

111

Q9Y256
DLLIPVGVMQPLTLR

PLXNA3

691

P51805
TPFIRPVMQALLHII

IPO7

536

O95373
VRLPLLPVDFLMGVV

KLHL8

256

Q9P2G9
MKIPVLPAVVLLSLL

KRTDAP

1

P60985
MIPRINAELLFRPTA

MORC3

481

Q14149
PGLLMTIIRFVLPLQ

COPB1

56

P53618
LGTPLRLPMLNTEVV

NEK8

321

Q86SG6
IILSPAMQAFVSLPR

NCKAP1L

806

P55160
YLRVTVMPLLTLPQT

LAX1

71

Q8IWV1
LLPMVIQLQLPRTGS

ALOX15

311

P16050
MSLFPSLPLLLLSMV

MBL2

1

P11226
MDPQTAPSRALLLLL

NPPB

1

P16860
SIIPLQLLTMLSPLE

HECTD4

3846

Q9Y4D8
LPPDQLISLLLTMFE

MROH1

1046

Q8NDA8
PPLLTDFVQSLLMKL

MROH9

251

Q5TGP6
TVITPMLNPIIYSLR

OR4D6

276

Q8NGJ1
LNTASLLSVLIPKMP

ORMDL1

126

Q9P0S3
LLPGLSLLDARVMTP

PAQR9

176

Q6ZVX9
LPEMLLPLAFVATLT

TM7SF2

126

O76062
VVARNGLLTMPIPIL

OR56A5

151

P0C7T3
VLATQAPRLPSTMLL

F2RL3

101

Q96RI0
ALMAVLLSAFPPLPV

MYO15B

576

Q96JP2
LLLGVNLVVMPPTRA

ACP2

16

P11117
LTMAPGLITLEIVPF

PAPSS1

546

O43252
LVIPMLNPLIYSLRN

OR8J1

281

Q8NGP2
TTFPPRLLAEQLTLM

RGL4

216

Q8IZJ4
MAPPSVPLVLLLVLL

GALP

1

Q9UBC7
ELSPLLMILSQLLPQ

ATM

431

Q13315
SEILIPLQSVMIPTL

ATR

2256

Q13535
PAMRLSVVLEALVPL

CCDC71

171

Q8IV32
LVLQLMPLKTFPAAI

IGSF23

41

A1L1A6
LPPQQLEASLRMLSL

C2CD3

2281

Q4AC94
LMSSEVFAPLLRLSP

E2F4

371

Q16254
SLPINPLSMLLNGIV

DOCK1

1516

Q14185
TLPINPLSMLLNGIV

DOCK2

1521

Q92608
LMNFLVSAVTKLPPI

EXT1

656

Q16394
LLTSPFLEPLMVVLV

DNAH3

266

Q8TD57
MQPSSLLPLALCLLA

CTSD

1

P07339
VTMYLPLLLVLVANP

GPR143

196

P51810
ERLLPVINTMLQLSP

GCC2

1636

Q8IWJ2
HPILLALILSMAVPT

DPY19L4

521

Q7Z388
PFLPGEVKTLMIQLL

CDK11A

521

Q9UQ88
MISLPGPLVTNLLRF

ESAM

1

Q96AP7
LEMSKFQPTLLTLPR

SERPING1

386

P05155
MPELVVTALLAPSRL

EPHX3

1

Q9H6B9
TSNIPEITPFLLFIM

ATP1A3

771

P13637
LLFIMANIPLPLGTI

ATP1A3

781

P13637
MARKSNLPVLLVPFL

AGA

1

P20933
FALPAATRIMLLPTP

LAMB4

661

A4D0S4
EALAIPQLPSLMPSL

HEATR1

1726

Q9H583
IAMLPPEQRQSILIL

CSTF2T

591

Q9H0L4
LLMAVRPSLPESGLL

FANCE

101

Q9HB96
PIAVIMTPTRELALQ

DDX46

446

Q7L014
PPSLLLLLASAMVEA

MT-CO1

106

P00395
LPPSALLTMLRTELR

HPS6

446

Q86YV9
IEMSAALPINPTIIR

CACNA1H

1701

O95180
EALPLSVTALLPSLM

SLC13A1

51

Q9BZW2
LAVTSLMPVLLFPLF

SLC13A5

56

Q86YT5
LMPVLLFPLFQILDS

SLC13A5

61

Q86YT5
LPIAVMNAISSLPLL

SLC15A5

346

A6NIM6
MNAISSLPLLILAPF

SLC15A5

351

A6NIM6
RVLPNVMSRLPSALL

SALL4

321

Q9UJQ4
LPQLAQPTLMIDFLT

NOC4L

281

Q9BVI4
ALTAPPEALLMVLPF

NOC4L

376

Q9BVI4
LEQFVSILMASIPLP

PNP

271

P00491
VPALPLLPLMSIFVN

SLC7A3

541

Q8WY07
MPSARLSGPVLALIL

GGT2P

276

P36268
RLLSLMDPLLPLSVL

LIPE

766

Q05469
DIVLMPELSTFRVLP

LGSN

146

Q5TDP6
TIVTPMLNPAIYTLR

OR4D5

276

Q8NGN0
PVAALIPEMPRLFLT

PIDD1

306

Q9HB75
TIVTPMLNPLIYSLR

OR2T11

276

Q8NH01
TVAIPMLNPLIYSLR

OR5D13

281

Q8NGL4
VARAVTLMTPLPFLL

OR52K1

151

Q8NGK4
VARAVTLMTPLPFLL

OR52K2

151

Q8NGK3
IPEGRLAIIFLPMFT

PARL

291

Q9H300
ILRFPLNILPMVISS

ABCC1

591

P33527
MRLPLLLVFASVIPG

MRC1

1

P22897
FLPMAVPILLSLVKI

PIGS

526

Q96S52
PSLPLPNVLLMANVT

GARIN1A

86

Q6NXP2
MNPSIRLLLILRDPS

HS3ST1

136

O14792
ASRVPAMLPSLLPVL

TAF3

671

Q5VWG9
PFLLPTMEVETLIRS

SZT2

2721

Q5T011
RLLPVINTMLQLSPE

RGPD4

1731

Q7Z3J3
LTRMFAPALPSDLLV

ROGDI

176

Q9GZN7
SLPMFTVLRKFTIPL

SLC35D2

116

Q76EJ3
ENRVLPMPTSIGIFL

TRIM36

656

Q9NQ86
PQMLSLLLLALPVLA

TPSD1

6

Q9BZJ3
MVFTPGLITLPRLLA

TREML2

166

Q5T2D2
PLASLVSMFLPNRSL

SLC52A3

346

Q9NQ40
SSPVVILPAVLLLFM

TMC3

681

Q7Z5M5
LPRLIAEPGLMLNFS

TMEM131L

581

A2VDJ0
PVPESALFILILTMS

LRRC41

236

Q15345
FLNRTVTLPFSVPIM

NKPD1

296

Q17RQ9
PLVAATMLLLLPPLS

MMP17

576

Q9ULZ9
SLLPVINTMLQLSPE

RGPD2

1721

P0DJD1
ILLLPELSFMTGIPE

PIWIL2

491

Q8TC59
AAFLMAALVPIPALR

PTCH2

511

Q9Y6C5
RVLILNDNLIPMLPT

SLITRK3

176

O94933
PTSPLDSNMLLVIIV

NEO1

1096

Q92859
MAALIPIPALRAFSL

PTCH1

561

Q13635
LGAVSPAVVVPSMLL

SLC9B2

241

Q86UD5
MVIALILFLLRPPNL

SMIM14

61

Q96QK8
MILLTLTGQPRFPTL

MT-ND5

426

P03915
FILTRNVLMTLPIPI

OR56A3

151

Q8NH54
NVLMTLPIPILSAQL

OR56A3

156

Q8NH54
KMISPDLPFLTIVLI

PGAP1

726

Q75T13
ATVPFLLQLAVMSPA

INTS5

336

Q6P9B9
PQQLLARLLVISMPA

MROH2B

506

Q7Z745
FQTREFIPLPRLLAM

URB1

411

O60287
RFQAAPVPLLLMILK

OMA1

141

Q96E52
ILASVILFANPISPM

SLC35B1

281

P78383
ATRMVVPLACLLTPL

SEC23B

31

Q15437
PLMQVELPISLLTRL

STK36

1026

Q9NRP7
ASLVAPLALMQTPLP

HTR3D

291

Q70Z44
VLMQLSPALVPAELL

ADGRG5

231

Q8IZF4
LTSNIPEITPFLMFI

ATP1A4

786

Q13733
VSIPMVRILAPVLVL

CD300LG

241

Q6UXG3
AFLSIMSPEIQLPLP

CIC

151

Q96RK0
LRLLFTMLEKSPLPI

NCAPD2

1056

Q15021
MLPQIPFLLLVSLNL

COL10A1

1

Q03692
SVLVMLLQQPDLLPS

CNOT11

106

Q9UKZ1
FLISRTRPPAPMQIL

SHANK2-AS3

61

Q9BTD1
MEALPPVRSSLLGIL

TMEM270

1

Q6UE05
SLSSMELIPIEFVLP

PIK3CG

31

P48736
LTVSLLGSLFPMPRV

SLC7A14

346

Q8TBB6
MAVLAPLIALVYSVP

TMX2

1

Q9Y320
LVLLLSFPSIMVPLA

TBXAS1

226

P24557
SFPSIMVPLARILPN

TBXAS1

231

P24557
RTQLGLPPLLLLTMA

TMEM59

11

Q9BXS4
LVPSAVALGMAIVPL

UNC93B1

161

Q9H1C4
LILPLMSQDLLKFPT

XPO4

961

Q9C0E2
MARPLVPSSQKALLL

CDC34

1

P49427
IRLQVMSLSPAPLSL

UNC80

1561

Q8N2C7
THPSLAIPELMRILV

PYGM

341

P11217
LPASPSVILPIQVML

RINT1

296

Q6NUQ1
LKVGPVPVLVMSLLF

SEC61B

66

P60468
LIASLIPTPRLHFLM

TUBG1

256

P23258
IPLLMLLSLAFAAPA

PLPPR3

71

Q6T4P5
PLPRRSISLAQMFVI

SPIDR

406

Q14159
LFNQILPLLMSPTLE

SF3B1

531

O75533
PISVSQMFQPIILLI

SOGA3

906

Q5TF21
ERNLPLSIGISMPIV

SLC7A7

256

Q9UM01
LTIEARFQPLLPETM

SELENON

156

Q9NZV5
IFQIIPLHSLSIMPR

ZNF546

16

Q86UE3
MFLSLPTLTVLIPLV

PIGY

1

Q3MUY2
THPALSIPELMRILV

PYGB

341

P11216
LLSSMFLPPLLIERL

UNC93A

51

Q86WB7
FVFSSLIPLLLMTPV

TMEM116

26

Q8NCL8
SMVLFSSPPVILLIS

PRNP

231

P04156
MLLPCRPVLTSVALN

MRPL2

46

Q5T653
MPAFNRLFPLASLVL

SCN3B

1

Q9NY72
VLRATPLADMTPQLL

TLNRD1

166

Q9H1K6
PLLQLLPVSNVVSVM

TMCO6

386

Q96DC7
IPLSAIIEVRTTMPL

SH2B2

251

O14492
TLLLCLSNLMFLPPV

TMEM8B

236

A6NDV4
LSNLMFLPPVVLAIR

TMEM8B

241

A6NDV4
VPFLVMISLLSLSPN

ROBO1

6

Q9Y6N7
ISLALPLLTIPMAFS

UBIAD1

281

Q9Y5Z9
PLLTIPMAFSLERQF

UBIAD1

286

Q9Y5Z9
NLPLAIGISMPIVTL

SLC7A6

266

Q92536
IFTMLSSLARLLFPP

TOP2A

806

P11388
LTPLPREMITLETVL

ATP6V0A4

86

Q9HBG4
LDRPFITLLPATTLM

XNDC1N

81

Q6ZNB5
SSIFLPRMNPFVLID

SLC30A6

191

Q6NXT4
MSPLRPLLLALALAS

SYCN

1

Q0VAF6
QVFPRLLSMTLSPDL

TBCD

601

Q9BTW9
LIASLIPTPRLHFLM

TUBG2

256

Q9NRH3
LLLGVDMLQSPLTRP

WSCD1

81

Q658N2
FLPRALALMPLIATS

WDR31

286

Q8NA23
LPITMAAGITQPLLT

WNK1

861

Q9H4A3
ANPGLIIPAILLMFL

TMC2

756

Q8TDI7
LIQSPVTTPLGLIML

XPO6

136

Q96QU8
PMFSLLLLLIVNPIN

POSTN

6

Q15063
ETALTRVVLPMPILV

SFXN5

251

Q8TD22
LALPLAISLFPQMSE

SFXN5

301

Q8TD22
LLDNMLLTVVVPIIP

SLC18A2

31

Q05940
IQQALTMFPGVLLPL

TCF25

451

Q9BQ70
VMLPTPVLRLLNVLD

UHMK1

316

Q8TAS1
PISQLLMIIAPSLGF

TIMD4

311

Q96H15
SPMKDRLNLPSVLVL

TBCEL

41

Q5QJ74
LPDLPVSLVLLSLIM

TMEM236

126

Q5W0B7
TLAAQILAVLLPPVM

TMEM101

201

Q96IK0
LRAMRLPILETAFPA

ZSWIM4

566

Q9H7M6
MAPPTGVLSSLLLLV

KIAA0319

1

Q5VV43
GAPLVTPSLLQMVRL

KIAA1522

816

Q9P206
PVIRAFLLFPTIERM

LDAH

156

Q9H6V9
LLLLTDPRFMSFVNP

MYOZ2

211

Q9NPC6