Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR1N2 GPR83 CCR10 OR8J2 PRLHR OR5AC1 DRD4 NPY5R OR4N5 GPR61 OR2B2 GPR25 OR4N4 OR5B12 OR5B2 OR13C5 TAS2R36 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 MRGPRX2 GPR87 OR2B3 OR5H2 OR6K3 TAS2R39 TAS2R20 NMBR OR52K2 OR2T4 OR1L1 CCKAR	1.42e-27	884	86	37	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR1N2 GPR83 CCR10 OR8J2 PRLHR ABCA1 OR5AC1 DRD4 NPY5R OR4N5 GPR61 OR2B2 GPR25 PLXNC1 OR4N4 OR5B12 OR5B2 OR13C5 TAS2R36 OR4D10 OR10V1 TLR5 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 MRGPRX2 GPR87 OR2B3 CD79B OR5H2 OR6K3 TAS2R39 TAS2R20 NMBR OR52K2 OR2T4 OR1L1 CCKAR CD200R1	1.52e-26	1353	86	42	GO:0004888
GeneOntologyMolecularFunction	olfactory receptor activity	OR1N2 OR8J2 OR5AC1 OR4N5 OR2B2 OR4N4 OR5B12 OR5B2 OR13C5 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 OR2B3 OR5H2 OR6K3 OR52K2 OR2T4 OR1L1	3.66e-19	431	86	23	GO:0004984
GeneOntologyMolecularFunction	odorant binding	OR8J2 OR5AC1 OR5B12 OR5B2 OR10V1 OR5H6 OR10K1 OR5B21 OR5H2 OR6K3	1.78e-10	127	86	10	GO:0005549
GeneOntologyMolecularFunction	neuropeptide receptor activity	GPR83 PRLHR NPY5R MRGPRX2 NMBR	3.21e-06	53	86	5	GO:0008188
GeneOntologyMolecularFunction	neuropeptide Y receptor activity	GPR83 PRLHR NPY5R	1.24e-05	11	86	3	GO:0004983
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	GPR83 PRLHR NPY5R MRGPRX2 NMBR CCKAR	2.37e-05	133	86	6	GO:0008528
GeneOntologyMolecularFunction	peptide receptor activity	GPR83 PRLHR NPY5R MRGPRX2 NMBR CCKAR	3.16e-05	140	86	6	GO:0001653
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA1 ABCA3 ABCA10 ABCA9	5.86e-05	49	86	4	GO:0140359
GeneOntologyMolecularFunction	lipid transporter activity	ABCA1 ABCA3 ATP8A2 SLCO1B3 ABCA10 ABCA9	2.03e-04	196	86	6	GO:0005319
GeneOntologyMolecularFunction	bitter taste receptor activity	TAS2R36 TAS2R39 TAS2R20	2.09e-04	27	86	3	GO:0033038
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ABCA1 ABCA3 ATP8A2	2.34e-04	28	86	3	GO:0140326
GeneOntologyMolecularFunction	guanylyltransferase activity	TENT4B TENT4A	3.80e-04	7	86	2	GO:0070568
GeneOntologyMolecularFunction	taste receptor activity	TAS2R36 TAS2R39 TAS2R20	3.83e-04	33	86	3	GO:0008527
GeneOntologyMolecularFunction	neuropeptide binding	PRLHR NPY5R MRGPRX2	5.39e-04	37	86	3	GO:0042923
GeneOntologyMolecularFunction	phosphatidylserine floppase activity	ABCA1 ATP8A2	6.47e-04	9	86	2	GO:0090556
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC38A2 ABCA1 ABCA3 SLC34A1 SLC26A2 SLCO1B3 ABCA10 ABCA9	1.04e-03	477	86	8	GO:0022804
GeneOntologyMolecularFunction	transporter activity	KCNV1 SLC38A2 KCNG2 ABCA1 ABCA3 TMC7 SLC34A1 SLC26A2 KCNV2 ATP8A2 SLCO1B3 TRPV3 ABCA10 ABCA9	1.16e-03	1289	86	14	GO:0005215
GeneOntologyMolecularFunction	poly(A) RNA polymerase activity	TENT4B TENT4A	1.18e-03	12	86	2	GO:1990817
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA1 ABCA3 ABCA10 ABCA9	1.26e-03	109	86	4	GO:0042626
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ABCA1 ABCA3 ATP8A2	1.38e-03	51	86	3	GO:0140303
GeneOntologyMolecularFunction	transmembrane transporter activity	KCNV1 SLC38A2 KCNG2 ABCA1 ABCA3 TMC7 SLC34A1 SLC26A2 KCNV2 SLCO1B3 TRPV3 ABCA10 ABCA9	1.56e-03	1180	86	13	GO:0022857
GeneOntologyMolecularFunction	glycerophospholipid flippase activity	ABCA3 ATP8A2	1.61e-03	14	86	2	GO:0140333
GeneOntologyMolecularFunction	floppase activity	ABCA1 ATP8A2	2.12e-03	16	86	2	GO:0140328
GeneOntologyMolecularFunction	flippase activity	ABCA3 ATP8A2	2.39e-03	17	86	2	GO:0140327
GeneOntologyMolecularFunction	phosphatidylcholine transporter activity	ABCA1 ABCA3	3.31e-03	20	86	2	GO:0008525
GeneOntologyMolecularFunction	phospholipid transporter activity	ABCA1 ABCA3 ATP8A2	4.01e-03	74	86	3	GO:0005548
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR1N2 GPR83 CCR10 OR8J2 PRLHR ABCA1 OR5AC1 DRD4 NPY5R OR4N5 GPR61 OR2B2 GPR25 OR4N4 OR5B12 OR5B2 OR13C5 TAS2R36 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 MRGPRX2 GPR87 OR2B3 OR5H2 OR6K3 TAS2R39 TAS2R20 NMBR OR52K2 OR2T4 ADCY1 OR1L1 CCKAR	2.92e-23	1395	86	39	GO:0007186
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR1N2 OR8J2 OR5AC1 OR4N5 OR2B2 OR4N4 OR5B12 OR5B2 OR13C5 TAS2R36 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 OR2B3 OR5H2 OR6K3 TAS2R39 TAS2R20 OR52K2 OR2T4 OR1L1	4.55e-22	485	86	26	GO:0050907
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR1N2 OR8J2 OR5AC1 OR4N5 OR2B2 OR4N4 OR5B12 OR5B2 OR13C5 TAS2R36 OR4D10 ATP8A2 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 OR2B3 OR5H2 OR6K3 TAS2R39 TAS2R20 OR52K2 OR2T4 OR1L1	2.73e-21	582	86	27	GO:0050906
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR1N2 OR8J2 OR5AC1 OR4N5 OR2B2 OR4N4 OR5B12 OR5B2 OR13C5 TAS2R36 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 OR2B3 OR5H2 OR6K3 TAS2R39 TAS2R20 OR52K2 OR2T4 OR1L1	3.20e-21	524	86	26	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR1N2 OR8J2 OR5AC1 OR4N5 OR2B2 OR4N4 OR5B12 OR5B2 OR13C5 TAS2R36 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 OR2B3 OR5H2 OR6K3 TAS2R39 TAS2R20 OR52K2 OR2T4 OR1L1	9.41e-21	547	86	26	GO:0007606
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR1N2 OR8J2 OR5AC1 OR4N5 OR2B2 OR4N4 OR5B12 OR5B2 OR13C5 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 OR2B3 OR5H2 OR6K3 OR52K2 OR2T4 OR1L1	1.90e-19	432	86	23	GO:0050911
GeneOntologyBiologicalProcess	detection of stimulus	OR1N2 OR8J2 OR5AC1 OR4N5 OR2B2 OR4N4 OR5B12 OR5B2 OR13C5 TAS2R36 OR4D10 ATP8A2 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 OR2B3 OR5H2 OR6K3 TAS2R39 TAS2R20 OR52K2 OR2T4 OR1L1	6.96e-19	722	86	27	GO:0051606
GeneOntologyBiologicalProcess	sensory perception of smell	OR1N2 OR8J2 OR5AC1 OR4N5 OR2B2 OR4N4 OR5B12 OR5B2 OR13C5 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 OR2B3 OR5H2 OR6K3 OR52K2 OR2T4 OR1L1	9.80e-19	465	86	23	GO:0007608
GeneOntologyBiologicalProcess	sensory perception	OR1N2 OR8J2 OR5AC1 OR4N5 OR2B2 OR4N4 OR5B12 OR5B2 OR13C5 TAS2R36 OR4D10 ATP8A2 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 MRGPRX2 OR2B3 OR5H2 OR6K3 TAS2R39 TAS2R20 OR52K2 OR2T4 OR1L1	1.45e-15	1072	86	28	GO:0007600
GeneOntologyBiologicalProcess	polyadenylation-dependent RNA catabolic process	TENT4B TENT4A	1.72e-05	2	86	2	GO:0043633
GeneOntologyBiologicalProcess	polyadenylation-dependent ncRNA catabolic process	TENT4B TENT4A	1.72e-05	2	86	2	GO:0043634
GeneOntologyBiologicalProcess	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening	TENT4B TENT4A	5.14e-05	3	86	2	GO:0060212
GeneOntologyBiologicalProcess	feeding behavior	GPR83 PRLHR NPY5R ATP8A2 UNC79 CCKAR	5.99e-05	162	86	6	GO:0007631
GeneOntologyBiologicalProcess	RNA 3' uridylation	TENT4B TENT4A	1.70e-04	5	86	2	GO:0071076
GeneOntologyBiologicalProcess	neuropeptide signaling pathway	GPR83 PRLHR NPY5R MRGPRX2 NMBR	1.71e-04	124	86	5	GO:0007218
GeneOntologyBiologicalProcess	positive regulation of 3'-UTR-mediated mRNA stabilization	TENT4B TENT4A	2.55e-04	6	86	2	GO:1905870
GeneOntologyBiologicalProcess	negative regulation of interleukin-6 production	CD24 NMBR PRG4 CD200R1	3.50e-04	80	86	4	GO:0032715
GeneOntologyBiologicalProcess	regulation of 3'-UTR-mediated mRNA stabilization	TENT4B TENT4A	3.56e-04	7	86	2	GO:1905868
GeneOntologyCellularComponent	TRAMP complex	TENT4B TENT4A	1.70e-04	5	87	2	GO:0031499
MousePheno	sweet preference	GPR83 UNC79	4.06e-05	3	52	2	MP:0011976
MousePheno	increased intestinal cholesterol absorption	ABCA1 CCKAR	4.06e-05	3	52	2	MP:0002646
MousePheno	abnormal food preference	GPR83 PRLHR UNC79	4.51e-05	19	52	3	MP:0001432
Domain	GPCR_Rhodpsn_7TM	OR1N2 GPR83 CCR10 PRLHR DRD4 NPY5R OR4N5 GPR61 OR2B2 GPR25 OR4N4 OR5B12 OR5B2 OR13C5 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 MRGPRX2 GPR87 OR2B3 OR5H2 OR6K3 NMBR OR52K2 OR2T4 OR1L1 CCKAR	7.36e-26	670	79	32	IPR017452
Domain	7tm_1	OR1N2 GPR83 CCR10 PRLHR DRD4 NPY5R OR4N5 GPR61 OR2B2 GPR25 OR4N4 OR5B12 OR5B2 OR13C5 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 MRGPRX2 GPR87 OR2B3 OR5H2 OR6K3 NMBR OR52K2 OR2T4 OR1L1 CCKAR	1.02e-25	677	79	32	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR1N2 GPR83 CCR10 PRLHR DRD4 NPY5R OR4N5 GPR61 OR2B2 GPR25 OR4N4 OR5B12 OR5B2 OR13C5 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 MRGPRX2 GPR87 OR2B3 OR5H2 OR6K3 NMBR OR52K2 OR2T4 OR1L1 CCKAR	1.46e-25	685	79	32	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR1N2 GPR83 CCR10 PRLHR DRD4 NPY5R OR4N5 GPR61 OR2B2 GPR25 OR4N4 OR5B12 OR5B2 OR13C5 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 MRGPRX2 GPR87 OR2B3 OR5H2 OR6K3 NMBR OR52K2 OR2T4 OR1L1 CCKAR	1.92e-25	691	79	32	PS50262
Domain	GPCR_Rhodpsn	OR1N2 GPR83 CCR10 PRLHR DRD4 NPY5R OR4N5 GPR61 OR2B2 GPR25 OR4N4 OR5B12 OR5B2 OR13C5 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 MRGPRX2 GPR87 OR2B3 OR5H2 OR6K3 NMBR OR52K2 OR2T4 OR1L1 CCKAR	2.01e-25	692	79	32	IPR000276
Domain	Olfact_rcpt	OR1N2 OR4N5 OR2B2 OR4N4 OR5B12 OR5B2 OR13C5 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 OR2B3 OR5H2 OR6K3 OR52K2 OR2T4 OR1L1	8.74e-18	393	79	21	IPR000725
Domain	ABC_A	ABCA1 ABCA3 ABCA10 ABCA9	1.43e-07	12	79	4	IPR026082
Domain	7TM_GPCR_Srsx	GPR83 PRLHR DRD4 NPY5R NMBR CCKAR	7.91e-06	112	79	6	SM01381
Domain	ABC_TRANSPORTER_2	ABCA1 ABCA3 ABCA10 ABCA9	5.01e-05	48	79	4	PS50893
Domain	ABC_tran	ABCA1 ABCA3 ABCA10 ABCA9	5.01e-05	48	79	4	PF00005
Domain	ABC_TRANSPORTER_1	ABCA1 ABCA3 ABCA10 ABCA9	5.44e-05	49	79	4	PS00211
Domain	ABC_transporter-like	ABCA1 ABCA3 ABCA10 ABCA9	5.89e-05	50	79	4	IPR003439
Domain	K_chnl_volt-dep_Kv	KCNV1 KCNG2 KCNV2	1.98e-04	27	79	3	IPR003968
Domain	VG_K_chnl	KCNV1 KCNG2 KCNV2	3.63e-04	33	79	3	IPR028325
Domain	PAP_assoc	TENT4B TENT4A	3.66e-04	7	79	2	IPR002058
Domain	PAP_assoc	TENT4B TENT4A	3.66e-04	7	79	2	PF03828
Domain	NPY_rcpt	GPR83 NPY5R	6.24e-04	9	79	2	IPR000611
Domain	ABC_transporter_CS	ABCA1 ABCA3 ABCA10	7.42e-04	42	79	3	IPR017871
Domain	NTP_transf_2	TENT4B TENT4A	9.48e-04	11	79	2	PF01909
Domain	Polymerase_NTP_transf_dom	TENT4B TENT4A	9.48e-04	11	79	2	IPR002934
Domain	Ion_trans_dom	KCNV1 KCNG2 KCNV2 TRPV3	1.39e-03	114	79	4	IPR005821
Domain	Ion_trans	KCNV1 KCNG2 KCNV2 TRPV3	1.39e-03	114	79	4	PF00520
Domain	BTB_2	KCNV1 KCNG2 KCNV2	1.47e-03	53	79	3	PF02214
Domain	T1-type_BTB	KCNV1 KCNG2 KCNV2	1.47e-03	53	79	3	IPR003131
Domain	Channel_four-helix_dom	KCNV1 KCNG2 KCNV2	1.81e-03	57	79	3	IPR027359
Domain	-	KCNV1 KCNG2 KCNV2	1.81e-03	57	79	3	1.20.120.350
Domain	AAA+_ATPase	ABCA1 ABCA3 ABCA10 ABCA9	3.25e-03	144	79	4	IPR003593
Domain	AAA	ABCA1 ABCA3 ABCA10 ABCA9	3.25e-03	144	79	4	SM00382
Domain	TAS2R	TAS2R39 TAS2R20	5.38e-03	26	79	2	PF05296
Domain	T2R	TAS2R39 TAS2R20	5.38e-03	26	79	2	IPR007960
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR1N2 OR8J2 OR5AC1 OR4N5 OR2B2 OR4N4 OR5B12 OR5B2 OR13C5 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 OR2B3 OR5H2 OR6K3 OR52K2 OR2T4 OR1L1	1.08e-17	417	75	23	M4072
Pathway	REACTOME_SENSORY_PERCEPTION	OR1N2 OR8J2 OR5AC1 OR4N5 OR2B2 OR4N4 OR5B12 OR5B2 OR13C5 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 OR2B3 OR5H2 OR6K3 TAS2R39 TAS2R20 OR52K2 OR2T4 OR1L1	9.01e-16	636	75	25	M41834
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR1N2 OR4N5 OR2B2 OR4N4 OR5B12 OR13C5 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR5B21 OR10A6 OR2B3 OR5H2 OR6K3 OR52K2 OR2T4 OR1L1	8.08e-15	389	75	20	M14091
Pathway	WP_GPCRS_ODORANT	GPR83 GPR61 GPR25 OR5H6 OR5B21 MRGPRX2 GPR87 OR5H2 TAS2R39 TAS2R20	9.81e-09	157	75	10	MM15872
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	GPR83 CCR10 PRLHR DRD4 NPY5R OR2B2 GPR25 GPR87 OR2B3 NMBR CCKAR	1.17e-07	260	75	11	M39397
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC38A2 ABCA1 ABCA3 MBTPS2 SLC34A1 SLC26A2 ATP8A2 STEAP4 SLCO1B3 TRPV3 UNC79 ADCY1 ABCA10 ABCA9	2.85e-05	736	75	14	M27287
Pathway	KEGG_ABC_TRANSPORTERS	ABCA1 ABCA3 ABCA10 ABCA9	8.54e-05	44	75	4	M11911
Pathway	REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS	ABCA3 ABCA10 ABCA9	1.11e-04	18	75	3	M524
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	GPR83 DRD4 NPY5R GPR87 NMBR CCKAR	4.61e-04	186	75	6	MM15994
Pathway	WP_GPCRS_PEPTIDE	CCR10 NPY5R NMBR CCKAR	5.20e-04	70	75	4	MM15959
Pathway	REACTOME_SIGNALING_BY_GPCR	GPR83 CCR10 PRLHR DRD4 NPY5R GPR25 TAS2R39 TAS2R20 NMBR ADCY1 CCKAR	5.81e-04	646	75	11	MM14962
Pathway	WP_PEPTIDE_GPCRS	CCR10 NPY5R NMBR CCKAR	6.75e-04	75	75	4	M39696
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC38A2 ABCA1 ABCA3 SLC34A1 SLC26A2 ATP8A2 STEAP4 SLCO1B3 TRPV3 UNC79 ABCA9	8.99e-04	681	75	11	MM14985
Pathway	REACTOME_SIGNALING_BY_GPCR	GPR83 CCR10 PRLHR DRD4 NPY5R GPR25 TAS2R39 TAS2R20 NMBR ADCY1 CCKAR	1.15e-03	702	75	11	M746
Pathway	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	KCNV1 KCNG2 KCNV2	1.33e-03	41	75	3	MM14546
Pathway	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	KCNV1 KCNG2 KCNV2	1.53e-03	43	75	3	M1056
Pubmed	The human olfactory receptor gene family.	OR1N2 OR5AC1 OR4N5 OR2B2 OR4N4 OR5B12 OR5B2 OR13C5 OR4D10 OR10V1 OR13C2 OR5H6 OR2G2 OR10K1 OR10A6 OR2B3 OR5H2 OR6K3 OR52K2 OR2T4 OR1L1	2.76e-19	541	88	21	14983052
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR1N2 OR5AC1 OR4N5 OR2B2 OR5B12 OR5B2 OR4D10 OR10V1 OR5H6 OR10K1 OR5B21 OR10A6 OR5H2 OR6K3 OR52K2 OR2T4	3.75e-16	340	88	16	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR1N2 OR5AC1 OR4N5 OR2B2 OR5B12 OR5B2 OR4D10 OR10V1 OR5H6 OR10K1 OR5B21 OR10A6 OR5H2 OR6K3 OR52K2 OR2T4	3.75e-16	340	88	16	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR1N2 OR5AC1 OR4N5 OR2B2 OR5B12 OR5B2 OR4D10 OR10V1 OR5H6 OR10K1 OR5B21 OR10A6 OR5H2 OR6K3 OR52K2 OR2T4	4.30e-16	343	88	16	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR1N2 OR5AC1 OR4N5 OR2B2 OR5B12 OR5B2 OR4D10 OR10V1 OR5H6 OR10K1 OR5B21 OR10A6 OR5H2 OR6K3 OR52K2 OR2T4	4.93e-16	346	88	16	14611657
Pubmed	Expression of the lipid transporters ABCA3 and ABCA1 is diminished in human breast cancer tissue.	ABCA1 ABCA3	6.33e-06	2	88	2	19902402
Pubmed	Mixed tailing by TENT4A and TENT4B shields mRNA from rapid deadenylation.	TENT4B TENT4A	6.33e-06	2	88	2	30026317
Pubmed	A novel conserved targeting motif found in ABCA transporters mediates trafficking to early post-Golgi compartments.	ABCA1 ABCA3	6.33e-06	2	88	2	21586796
Pubmed	Relationship between SLCO1B3 and ABCA3 polymorphisms and imatinib response in chronic myeloid leukemia patients.	ABCA3 SLCO1B3	6.33e-06	2	88	2	25056761
Pubmed	Increased Expression of the ABCA1 and ABCA3 Transporter Genes is Associated with Cisplatin Resistance in Breast Cancer Cells.	ABCA1 ABCA3	6.33e-06	2	88	2	38019257
Pubmed	Essential roles of dopamine D4 receptors and the type 1 adenylyl cyclase in photic control of cyclic AMP in photoreceptor cells.	DRD4 ADCY1	6.33e-06	2	88	2	19166506
Pubmed	The topoisomerase-related function gene TRF4 affects cellular sensitivity to the antitumor agent camptothecin.	TENT4B TENT4A	6.33e-06	2	88	2	10066793
Pubmed	Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita.	TENT4B TENT4A	6.33e-06	2	88	2	32559291
Pubmed	Understanding the phenotypic similarities between IFAP and Olmsted syndrome from a molecular perspective: the interaction of MBTPS2 and TRPV3.	MBTPS2 TRPV3	6.33e-06	2	88	2	28717930
Pubmed	Dopamine D₄ receptor activation controls circadian timing of the adenylyl cyclase 1/cyclic AMP signaling system in mouse retina.	DRD4 ADCY1	6.33e-06	2	88	2	21676039
Pubmed	The ZCCHC14/TENT4 complex is required for hepatitis A virus RNA synthesis.	TENT4B TENT4A	1.90e-05	3	88	2	35867748
Pubmed	Air1 zinc knuckles 4 and 5 and a conserved IWRXY motif are critical for the function and integrity of the Trf4/5-Air1/2-Mtr4 polyadenylation (TRAMP) RNA quality control complex.	TENT4B TENT4A	1.90e-05	3	88	2	21878619
Pubmed	Examining the role of ABC lipid transporters in pulmonary lipid homeostasis and inflammation.	ABCA1 ABCA3	1.90e-05	3	88	2	28241820
Pubmed	Viral hijacking of the TENT4-ZCCHC14 complex protects viral RNAs via mixed tailing.	TENT4B TENT4A	1.90e-05	3	88	2	32451488
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR1N2 OR5B12 OR5B2 OR4D10 OR10V1 OR2B3	2.05e-05	219	88	6	12213199
Pubmed	Circadian rhythm of contrast sensitivity is regulated by a dopamine-neuronal PAS-domain protein 2-adenylyl cyclase 1 signaling pathway in retinal ganglion cells.	DRD4 ADCY1	3.79e-05	4	88	2	24048828
Pubmed	Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.	OR5AC1 OR10V1 OR5H2	4.38e-05	27	88	3	32061665
Pubmed	Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.	ABCA1 ABCA9	6.30e-05	5	88	2	12532264
Pubmed	ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol.	ABCA1 ABCA3	6.30e-05	5	88	2	17142808
Pubmed	Personal receptor repertoires: olfaction as a model.	OR8J2 OR5H6 OR10A6	1.24e-04	38	88	3	22908908
Pubmed	Lewis(x) and alpha2,3-sialyl glycans and their receptors TAG-1, Contactin, and L1 mediate CD24-dependent neurite outgrowth.	CCR10 CD24	1.32e-04	7	88	2	19458237
Pubmed	Neuropeptide Y family receptors traffic via the Bardet-Biedl syndrome pathway to signal in neuronal primary cilia.	GPR83 NPY5R	1.32e-04	7	88	2	24316073
Pubmed	International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.	KCNV1 KCNG2 KCNV2	1.45e-04	40	88	3	16382104
Pubmed	Endogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.	ABCA1 ABCA3	1.75e-04	8	88	2	24293640
Pubmed	The human ATP-binding cassette (ABC) transporter superfamily.	ABCA10 ABCA9	2.81e-04	10	88	2	11435397
Pubmed	Poor replication of candidate genes for major depressive disorder using genome-wide association data.	ACSL4 DRD4 CCKAR	2.99e-04	51	88	3	20351714
Pubmed	Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database.	DRD4 RTN4 CCKAR	3.16e-04	52	88	3	18583979
Pubmed	A common variant in DRD3 receptor is associated with autism spectrum disorder.	DRD4 NPY5R ST7 ADCY1	3.21e-04	128	88	4	19058789
Pubmed	gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression.	CD79B ADCY1	3.43e-04	11	88	2	10808179
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	SLC38A2 MYOF NF1 MROH1 TMEM237 SLC26A2 ST7 RTN4 DOLK DPY19L4	3.51e-04	1061	88	10	33845483
Pubmed	Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human.	OR13C5 OR13C2	4.11e-04	12	88	2	12906860
Pubmed	Developmental expression of the oligodendrocyte myelin glycoprotein in the mouse telencephalon.	NF1 RTN4	5.65e-04	14	88	2	19892785
Pubmed	Parallel ascending spinal pathways for affective touch and pain.	GPR83 MRGPRX2	5.65e-04	14	88	2	33116307
Pubmed	Identification of G Protein-Coupled Receptors (GPCRs) in Primary Cilia and Their Possible Involvement in Body Weight Control.	PRLHR NPY5R	6.51e-04	15	88	2	26053317
Pubmed	Tissue distribution, ontogeny, and hormonal regulation of xenobiotic transporters in mouse kidneys.	ABCA1 SLC34A1	7.42e-04	16	88	2	19679677
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR5AC1 OR2B2 OR2T4	8.91e-04	74	88	3	15081110
Pubmed	C-LTMRs mediate wet dog shakes via the spinoparabrachial pathway.	GPR83 MRGPRX2	1.05e-03	19	88	2	38915692
Pubmed	Dissociation of heterotrimeric g proteins in cells.	CCR10 DRD4 NPY5R CCKAR	1.13e-03	179	88	4	18577758
Pubmed	Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.	GPR83 TMC7	1.17e-03	20	88	2	22566498
Pubmed	Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac.	CD93 CD24	1.41e-03	22	88	2	9324354
Pubmed	Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.	ABCA10 ABCA9	1.41e-03	22	88	2	8894702
Pubmed	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.	TAS2R39 TAS2R20	1.41e-03	22	88	2	12734386
Pubmed	A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior.	CD24 CCKAR	1.55e-03	23	88	2	35065713
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	ACSL4 SLC38A2 SLC26A2 ST7 RTN4 DOP1B	1.79e-03	504	88	6	34432599
Pubmed	Comparative analysis of 1196 orthologous mouse and human full-length mRNA and protein sequences.	NF1 SLC26A2	1.83e-03	25	88	2	8889551
Pubmed	Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins.	GPR83 PRLHR	1.83e-03	25	88	2	28154160
Pubmed	Receptors for bitter and sweet taste.	TAS2R39 TAS2R20	1.83e-03	25	88	2	12139982
Pubmed	Molecular mechanisms of bitter and sweet taste transduction.	TAS2R39 TAS2R20	1.98e-03	26	88	2	11696554
Pubmed	Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.	TAS2R39 TAS2R20	2.13e-03	27	88	2	12581520
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	GPR61 TRPV3 CD200R1	2.18e-03	101	88	3	23382219
Pubmed	Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.	TAS2R39 TAS2R20	2.29e-03	28	88	2	15744053
Cytoband	11q12.1	OR8J2 OR5B12 OR5B2 OR4D10 OR10V1 OR5B21	6.76e-07	161	87	6	11q12.1
Cytoband	Ensembl 112 genes in cytogenetic band chr11q12	OR8J2 OR5B12 OR5B2 OR4D10 OR10V1 OR5B21	5.22e-05	345	87	6	chr11q12
Cytoband	9q31.1	ABCA1 OR13C5 OR13C2	6.65e-05	41	87	3	9q31.1
Cytoband	Ensembl 112 genes in cytogenetic band chr3q11	OR5AC1 OR5H6 OR5H2	1.52e-04	54	87	3	chr3q11
Cytoband	3q12.1	OR5H6 OR5H2	7.28e-04	21	87	2	3q12.1
Cytoband	Ensembl 112 genes in cytogenetic band chr9q31	ABCA1 OR13C5 OR13C2	2.29e-03	137	87	3	chr9q31
Cytoband	9q33.2	OR1N2 OR1L1	2.51e-03	39	87	2	9q33.2
Cytoband	1q23.1	OR10K1 OR6K3	3.48e-03	46	87	2	1q23.1
GeneFamily	ATP binding cassette subfamily A	ABCA1 ABCA3 ABCA10 ABCA9	2.25e-07	14	72	4	805
GeneFamily	Olfactory receptors, family 5	OR5AC1 OR5B12 OR5B2 OR5H6 OR5B21 OR5H2	5.53e-06	112	72	6	152
GeneFamily	G protein-coupled receptors, Class A orphans	GPR83 GPR61 GPR25 MRGPRX2 GPR87	1.47e-05	78	72	5	262
GeneFamily	Non-canonical poly(A) polymerases	TENT4B TENT4A	3.24e-04	7	72	2	1318
GeneFamily	Taste 2 receptors	TAS2R36 TAS2R39 TAS2R20	4.99e-04	39	72	3	1162
GeneFamily	Potassium voltage-gated channels	KCNV1 KCNG2 KCNV2	5.38e-04	40	72	3	274
GeneFamily	Maestro heat like repeat containing	MROH1 MROH5	8.40e-04	11	72	2	636
GeneFamily	Olfactory receptors, family 2	OR2B2 OR2G2 OR2B3 OR2T4	1.07e-03	113	72	4	149
GeneFamily	Olfactory receptors, family 10	OR10V1 OR10K1 OR10A6	2.32e-03	66	72	3	157
GeneFamily	Olfactory receptors, family 13	OR13C5 OR13C2	3.75e-03	23	72	2	162
GeneFamily	Olfactory receptors, family 1	OR1N2 OR1L1	1.11e-02	40	72	2	147
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CD93 CHODL	1.16e-02	41	72	2	1298
GeneFamily	Olfactory receptors, family 4	OR4N5 OR4N4 OR4D10	1.48e-02	129	72	3	151
GeneFamily	Defensins, beta	DEFB104A DEFB135	1.51e-02	47	72	2	503
Coexpression	GSE13762_CTRL_VS_125_VITAMIND_DAY12_DC_UP	SLC38A2 GPR83 NF1 TMEM237 DPY19L4 CD200R1	5.80e-06	148	79	6	M1892
Coexpression	GSE4590_SMALL_VS_LARGE_PRE_BCELL_UP	TSPAN15 CD93 ACSL4 MYOF PLXNC1 CD24	1.51e-05	175	79	6	M6872
Coexpression	RAO_BOUND_BY_SALL4_ISOFORM_A	OR1N2 ABCA1 OR4D10 OR5H2 PRG4 CCKAR	2.70e-05	194	79	6	M2517
Coexpression	RAO_BOUND_BY_SALL4_ISOFORM_A	OR1N2 ABCA1 OR4D10 OR5H2 PRG4 CCKAR	4.21e-05	210	79	6	MM958
Disease	Colorectal Carcinoma	CD93 ACSL4 ABCA1 ABCA3 NF1 RTN4 SLCO1B3 GPR87 ABCA10 ABCA9	1.79e-05	702	79	10	C0009402
Disease	Olmsted syndrome	MBTPS2 TRPV3	2.12e-05	3	79	2	C2609071
Disease	Hypoxanthine measurement	TSPAN15 GPR61	5.42e-04	13	79	2	EFO_0021604
Disease	Alcohol abuse	DRD4 NPY5R CCKAR	7.82e-04	67	79	3	C0085762
Disease	thyroglobulin measurement	OR5B12 OR5B21	8.29e-04	16	79	2	EFO_0010050
Disease	Colorectal Neoplasms	ABCA1 ABCA3 SLCO1B3 ABCA10 ABCA9	9.00e-04	277	79	5	C0009404
Disease	HDL cholesterol change measurement	ABCA1 ABCA10	1.88e-03	24	79	2	EFO_0007805
Disease	alcohol use disorder (implicated_via_orthology)	PRLHR NPY5R UNC79 ADCY1	1.89e-03	195	79	4	DOID:1574 (implicated_via_orthology)
Disease	obesity (is_implicated_in)	ABCA1 NPY5R CCKAR	1.89e-03	91	79	3	DOID:9970 (is_implicated_in)
Disease	Bone Diseases, Developmental	SLC34A1 SLC26A2	2.38e-03	27	79	2	C0005941
Disease	neuroblastoma, cutaneous melanoma	CHODL SMLR1	2.56e-03	28	79	2	EFO_0000389, EFO_0000621

Protein segments in the cluster

Peptide	Gene	Start	Entry
ILLPVHLLITIYSAL	ACSL4	11	O60488
LGLLLLALLLPTQIY	CD24	11	P25063
FVVLQLPYSLALLLD	CCR10	256	P46092
LYTLVLVLQPQRVLL	NUDT1	6	P36639
LLTTLIPYLQSVIFL	ABCA10	1116	Q8WWZ4
LLIPYLHFLIFLFIL	ABCA9	1206	Q8IUA7
LLLLTFVLPLVVTLF	GPR25	206	O00155
SSTNLPVLALLLLLY	ABCA1	1731	O95477
LLLFYILGTVVAILL	CD93	581	Q9NPY3
LVAIQYQLPLLLLLS	ABCA3	256	Q99758
PAVQILLYSLIFLLS	CCKAR	41	P32238
TLLIILFIIVPIFLL	CD79B	166	P40259
FIILYNNLIPISLLV	ATP8A2	366	Q9NTI2
LVFVLILIFYLIILP	OR4N4C	26	A0A096LPK9
ILIFYLIILPGNFLI	OR4N4C	31	A0A096LPK9
VLPYLVLVLKQFLLQ	TENT4B	256	Q8NDF8
PLLFIYTFIIIDNLL	OR6K3	46	Q8NGY3
YIISFIVLSIPLSLI	OR10V1	201	Q8NGI7
FFSVLILLIPVTLIL	OR2B3	201	O76000
FVLILILYLLTILGN	OR2G2	31	Q8NGZ5
LQIPLLLAFLFIYLI	OR5B21	21	A6NL26
IFLVYFLIPLAIISI	NMBR	216	P28336
VFAVLYFLLPLLLIL	GPR61	211	Q9BZJ8
TQIDNLLLPLYLLIL	DOLK	521	Q9UPQ8
LLVFLLDVIPLELYS	DOP1B	481	Q9Y3R5
NIIDLLAILPFYITL	KCNV1	276	Q6PIU1
LAILPFYITLLVESL	KCNV1	281	Q6PIU1
YFLIVLPVLLVIVIF	PLXNC1	946	O60486
LNIIDILALLPFYVS	KCNG2	251	Q9UJ96
IPVVIISSSYLLILL	OR2T4	241	Q8NH00
LVFVLILIFYLIILP	OR4N4	26	Q8N0Y3
ILIFYLIILPGNFLI	OR4N4	31	Q8N0Y3
LVFVLVLIFYLIILP	OR4N5	26	Q8IXE1
LQIPLFILFTFIYLL	OR5B2	21	Q96R09
PLFLVFLVIYLITIV	OR5H2	31	Q8NGV7
AKLYIPYIILTIIIL	CD200R1	241	Q8TD46
FLLTPLLLIIVSYTL	OR13C5	206	Q8NGS8
FILTPLLLIIVSYTL	OR13C2	206	Q8NGS9
LQIPLFIVFLFIYLI	OR5B12	21	Q96R08
VLELYPQLFVVLLLR	MROH1	1216	Q8NDA8
LATFILLYILPLLII	GPR83	241	Q9NYM4
LLYILPLLIISVAYA	GPR83	246	Q9NYM4
LLLALLVLPLFVYSE	DRD4	81	P21917
PVLYLIIFVASILLN	GPR87	46	Q9BY21
LLPYLILVLKQFLLQ	TENT4A	356	Q5XG87
FLPIYLITVIGNLLI	OR1L1	81	Q8NH94
IPLFLAFLVIYLITI	OR5H6	41	Q8NGV6
VLYLLVCFLLLPSLV	SLC34A1	516	Q06495
PLFLVFLVIYLITLV	OR5AC1	26	P0C628
PLFLVFLVLYLLTVA	OR8J2	26	Q8NGG1
VYLLIFPQSVVVLLL	ADCY1	626	Q08828
IILVLIALPSLRILY	MT-CO2	71	P00403
VLLALVVLNLLFYVP	DEFB135	6	Q30KP9
LLLAISLLLYQDLPV	DEFB104A	6	Q8WTQ1
LTQSSLLPFYILVLI	DPY19L4	416	Q7Z388
ILALVLLPVILLPFY	MBTPS2	236	O43462
IILVPFLLILLSYIR	OR10A6	206	Q8NH74
PQLELVLFVVLLIFY	OR2B8P	21	P59922
FISVLFLLIPVTLIL	OR2B2	201	Q9GZK3
ALVIPLLLILVSYIR	OR10K1	206	Q8NGX5
LLFLTVPLLLIVFSY	OR1N2	221	Q8NGR9
LDLLLVILSYIFILQ	OR52K2	211	Q8NGK3
FFLLLVSYIVILSLP	OR4D10	211	Q8NGI6
ILILTKFLYSPVLLE	MROH5	1021	Q6ZUA9
LILALISLFSVPVIY	RTN4	1141	Q9NQC3
IPFTLTLISFLLLIY	TAS2R20	186	P59543
IPFTLTLISFLLLIY	TAS2R36	186	P0DTE0
PFLITLILAVLLAEY	TAS2R39	31	P59534
LVTYLLPLLVILLSY	PRLHR	231	P49683
LIYTCLLLFSVLLPL	TMEM185B	16	Q9H7F4
FTISLLLVQYILPLV	NPY5R	211	Q15761
NLVDLVAILPLYLQL	KCNV2	336	Q8TDN2
EAVRLLILILKLFYP	STAG3L1	106	P0CL83
VLFLVYILRVPLKIN	ST7	31	Q9NRC1
LPLTRLYLTILLTVL	MRGPRX2	216	Q96LB1
LPIYLLLLLSVFVIQ	PRG4	6	Q92954
VPLLVALLLTLLLAY	SGCA	296	Q16586
PVTLLLLLLIAYFRI	SMLR1	61	H3BR10
LLLVLYTLVLLLVPS	CHST7	16	Q9NS84
NLIYVVIPTIPLLLL	CHODL	216	Q9H9P2
PFQSLLYLLLALSTI	TMEM237	271	Q96Q45
LVLLVIAPLFYSLQK	SLC26A2	466	P50443
YLVLLVSLVVILPLS	SLC38A2	196	Q96QD8
SILTNPLYVIFLLLT	SLCO1B3	331	Q9NPD5
PLYVIFLLLTLLQVS	SLCO1B3	336	Q9NPD5
ILLPQFLGVLLTLLY	TSPAN15	241	O95858
YLQKLLDPLLRIVIT	NF1	1296	P21359
IFPITALTLLALVYL	STEAP4	246	Q687X5
FLLLVPLLVLALASY	TMEM88	96	Q6PEY1
PILFLFLLITYVILT	TRPV3	651	Q8NET8
LYFLLRVPHLQILIL	TLR5	441	O60602
VPLILARLLLIFDYL	UBR4	851	Q5T4S7
ILYLPSIVITLANFI	TMC7	406	Q7Z402
YVTLVTLLDLVPLLQ	UNC79	131	Q9P2D8
ILLLFVAVLLYSLPN	MYOF	2036	Q9NZM1