Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

IL18 REC114 ZNF148 SPATA31A3 COMT ING2 AVPR1A TOPAZ1 SPATA31A7 TTLL5 SPATA31A6 SPATA31A5 CCNB1 DNAH1 CITED2 SPATA31A1 CFAP61 CNR1 HDAC2

2.12e-0611949619GO:0048609
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

2.65e-0712924PF15371
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

2.65e-0712924IPR027970
Domain-

AP1B1 AP2B1

2.40e-0529222.60.40.1150
DomainClathrin_b-adaptin_app_Ig-like

AP1B1 AP2B1

2.40e-052922IPR013037
DomainAP_complex_bsu_1_2_4

AP1B1 AP2B1

7.18e-053922IPR016342
DomainB2-adapt-app_C

AP1B1 AP2B1

7.18e-053922PF09066
DomainB-adaptin_app_sub_C

AP1B1 AP2B1

1.43e-044922IPR015151
DomainB2-adapt-app_C

AP1B1 AP2B1

1.43e-044922SM01020
DomainAP_beta

AP1B1 AP2B1

2.38e-045922IPR026739
DomainBeta2_adaptin/TBP_C_dom

AP1B1 AP2B1

3.55e-046922IPR012295
Domain-

AP1B1 AP2B1

3.55e-0469223.30.310.10
DomainCoatomer/calthrin_app_sub_C

AP1B1 AP2B1

6.59e-048922IPR009028
DomainClathrin_a/b/g-adaptin_app_Ig

AP1B1 AP2B1

8.45e-049922IPR008152
DomainAlpha_adaptinC2

AP1B1 AP2B1

8.45e-049922PF02883
DomainAlpha_adaptinC2

AP1B1 AP2B1

8.45e-049922SM00809
DomainARM-type_fold

PSMD5 XPO1 TRRAP AP1B1 AP2B1 VPS35 EIF4G2

1.43e-03339927IPR016024
DomainCoatomer/clathrin_app_Ig-like

AP1B1 AP2B1

1.53e-0312922IPR013041
DomainClathrin/coatomer_adapt-like_N

AP1B1 AP2B1

2.42e-0315922IPR002553
DomainAdaptin_N

AP1B1 AP2B1

2.42e-0315922PF01602
DomainIon_trans_dom

CACNA1E TRPM7 RYR1 KCNA10

2.43e-03114924IPR005821
DomainIon_trans

CACNA1E TRPM7 RYR1 KCNA10

2.43e-03114924PF00520
Domain-

PSMD5 XPO1 TRRAP AP1B1 AP2B1

4.83e-032229251.25.10.10
Pubmed

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1

9.10e-13697520850414
Pubmed

Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1

9.10e-13697525930072
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1

6.20e-092497532212159
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

MAN2C1 MCM4 XPO1 TRRAP DDX5 AP1B1 VPS35 EIF4G2 GMPPB

5.43e-0734497930333137
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

MCM4 XPO1 STAT1 DDX5 ATAD3B AP1B1 AP2B1 VPS35 EIF4G2 KLB

5.60e-07451971036168627
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

SNF8 CACNA1E ZNF148 TRPM7 NOX4 NEB RYR1 DDX5 FAN1 NFE2L2 ETHE1 ZNF638 ZNF79 DEPDC5 HYDIN HDAC2

5.66e-071293971615342556
Pubmed

Keap1-MCM3 interaction is a potential coordinator of molecular machineries of antioxidant response and genomic DNA replication in metazoa.

MCMBP MCM4 NFE2L2

1.75e-06997330108253
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

MCM4 XPO1 IDH3A CCNB1 AP1B1 AP2B1 FDFT1 VPS35 EIF4G2 HDAC2

3.88e-06560971035241646
Pubmed

ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

ING2 MCM4 TRRAP HDAC2

5.87e-064297416387653
Pubmed

Nrf2 regulates hyperoxia-induced Nox4 expression in human lung endothelium: identification of functional antioxidant response elements on the Nox4 promoter.

NOX4 NFE2L2

7.70e-06297221443946
Pubmed

Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress.

NFE2L2 HDAC2

7.70e-06297221320471
Pubmed

MCM4 potentiates evasion of hepatocellular carcinoma from sorafenib-induced ferroptosis through Nrf2 signaling pathway.

MCM4 NFE2L2

7.70e-06297239276458
Pubmed

Nicotinamide adenine dinucleotide phosphate oxidase-4-dependent upregulation of nuclear factor erythroid-derived 2-like 2 protects the heart during chronic pressure overload.

NOX4 NFE2L2

7.70e-06297225534702
Pubmed

NADPH Oxidase 4 (Nox4) Suppresses Mitochondrial Biogenesis and Bioenergetics in Lung Fibroblasts via a Nuclear Factor Erythroid-derived 2-like 2 (Nrf2)-dependent Pathway.

NOX4 NFE2L2

7.70e-06297228049732
Pubmed

KLB and NOX4 expression levels as potential blood-based transcriptional biomarkers of physical activity in children.

NOX4 KLB

7.70e-06297237019912
Pubmed

RNA helicase DDX5 enables STAT1 mRNA translation and interferon signalling in hepatitis B virus replicating hepatocytes.

STAT1 DDX5

7.70e-06297234021034
Pubmed

Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction.

NFE2L2 HDAC2

7.70e-06297221094147
Pubmed

Nuclear factor erythroid 2-related factor 2 facilitates neuronal glutathione synthesis by upregulating neuronal excitatory amino acid transporter 3 expression.

SLC1A1 NFE2L2

7.70e-06297221593323
Pubmed

Brain adaptation to hypoxia and hyperoxia in mice.

NOX4 NFE2L2

7.70e-06297227835780
Pubmed

Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance.

NOX4 NFE2L2

7.70e-06297224718857
Pubmed

Mechanism of Stat1 in the neuronal Ca2+ overload after intracerebral hemorrhage via the H3K27ac/Trpm7 axis.

TRPM7 STAT1

7.70e-06297235642851
Pubmed

Cancer cell-expressed SLAMF7 is not required for CD47-mediated phagocytosis.

CD47 SLAMF7

7.70e-06297230710089
Pubmed

Antroquinonol differentially modulates T cell activity and reduces interleukin-18 production, but enhances Nrf2 activation, in murine accelerated severe lupus nephritis.

IL18 NFE2L2

7.70e-06297221905011
Pubmed

Lethal multiple pterygium syndrome, large cystic hygroma, and cleft palate: Rare and severe fetal presentations of RYR1- and NEB-related congenital myopathies.

NEB RYR1

7.70e-06297238520674
Pubmed

Aging-related NOX4-Nrf2 redox imbalance increases susceptibility to cisplatin-induced acute kidney injury by regulating mitophagy.

NOX4 NFE2L2

7.70e-06297238104863
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

COL4A3 TOPAZ1 XPO1 NEB SMC5 TRRAP SPATA31A6 VPS35 HYDIN

1.09e-0549797936774506
Pubmed

Mitochondrial ROS driven by NOX4 upregulation promotes hepatocellular carcinoma cell survival after incomplete radiofrequency ablation by inducing of mitophagy via Nrf2/PINK1.

NOX4 NFE2L2

2.31e-05397236964576
Pubmed

Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation.

STAT1 HDAC2

2.31e-05397232102981
Pubmed

Functional domains of histone deacetylase-3.

XPO1 HDAC2

2.31e-05397211779848
Pubmed

Central actions of neuromedin U via corticotropin-releasing hormone.

IL18 NMU

2.31e-05397214623274
Pubmed

Chromosomal localization of genes encoding CAN/Nup214-interacting proteins--human CRM1 localizes to 2p16, whereas Nup88 localizes to 17p13 and is physically linked to SF2p32.

XPO1 STAT1

2.31e-0539729205132
Pubmed

CITED2 inhibits STAT1-IRF1 signaling and atherogenesis.

STAT1 CITED2

2.31e-05397234365659
Pubmed

The effect of p53 on the activity of NRF2 and NDRG2 genes through apoptotic pathway in IDH-wildtype glioblastoma.

NDRG2 NFE2L2

2.31e-05397238241776
Pubmed

TRPM7 modulates macrophage polarization by STAT1/STAT6 pathways in RAW264.7 cells.

TRPM7 STAT1

2.31e-05397233153718
Pubmed

Sirt1/Nrf2 pathway is involved in oocyte aging by regulating Cyclin B1.

CCNB1 NFE2L2

2.31e-05397230368232
Pubmed

miR-100a-5p-enriched exosomes derived from mesenchymal stem cells enhance the anti-oxidant effect in a Parkinson's disease model via regulation of Nox4/ROS/Nrf2 signaling.

NOX4 NFE2L2

2.31e-05397237875930
Pubmed

Genotype effects of CHRNA7, CNR1 and COMT in schizophrenia: interactions with tobacco and cannabis use.

COMT CNR1

2.31e-05397217978319
Pubmed

Endothelial HO-1 induction by model TG-rich lipoproteins is regulated through a NOX4-Nrf2 pathway.

NOX4 NFE2L2

2.31e-05397227185859
Pubmed

IL-18 stimulates IL-13-mediated IFN-gamma-sensitive host resistance in vivo.

IL18 DDX5

2.31e-05397216568498
Pubmed

Upregulation of cannabinoid receptor-1 and fibrotic activation of mouse hepatic stellate cells during Schistosoma J. infection: role of NADPH oxidase.

NOX4 CNR1

2.31e-05397224657416
Pubmed

Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4.

NOX4 RYR1

2.31e-05397221896730
Pubmed

Macrophage-derived extracellular vesicles regulates USP5-mediated HDAC2/NRF2 axis to ameliorate inflammatory pain.

NFE2L2 HDAC2

2.31e-05397234423867
Pubmed

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.

RYR1 SPHKAP CNR1

3.12e-052297326494785
Pubmed

Proteomic and Interactome Approaches Reveal PAK4, PHB-2, and 14-3-3η as Targets of Overactivated Cdc42 in Cellular Responses to Genomic Instability.

COMT TRIO XPO1 TRRAP STAT1 EHD2

4.15e-0522597631478661
Pubmed

Short-Term In Vitro ROS Detection and Oxidative Stress Regulators in Epiretinal Membranes and Vitreous from Idiopathic Vitreoretinal Diseases.

NOX4 NFE2L2

4.60e-05497236567907
Pubmed

Biopsychosocial influence on exercise-induced injury: genetic and psychological combinations are predictive of shoulder pain phenotypes.

COMT AVPR1A

4.60e-05497224373571
Pubmed

Mechanistic insights of NAC1 nuclear export and its role in ovarian cancer resistance to docetaxel.

XPO1 CCNB1

4.60e-05497237019189
Pubmed

Association of epidermal growth factor receptors with coated pit adaptins via a tyrosine phosphorylation-regulated mechanism.

AP1B1 AP2B1

4.60e-0549727534311
Pubmed

Construction of a transcription map surrounding the BRCA1 locus of human chromosome 17.

EZH1 DDX5

4.60e-0549727774924
Pubmed

Role of activation of PIP5Kgamma661 by AP-2 complex in synaptic vesicle endocytosis.

AP1B1 AP2B1

4.60e-05497217290217
Pubmed

ATM binds to beta-adaptin in cytoplasmic vesicles.

AP1B1 AP2B1

4.60e-0549729707615
Pubmed

Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate.

MCMBP MCM4 NFE2L2

4.63e-052597327621311
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

ZNF148 MCM4 EZH1 TRRAP CCNB1 RTL9 ZNF638 HYDIN

5.22e-0546997827634302
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

TOM1L2 TRIO MCM4 EZH1 CCNB1 AP2B1 VPS35

6.71e-0535897732460013
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

MCM4 XPO1 IDH3A DDX5 AP1B1 AP2B1 VPS35 EIF4G2 HDAC2

7.57e-0563897933239621
Pubmed

Keap1 controls protein S-nitrosation and apoptosis-senescence switch in endothelial cells.

NOX4 NFE2L2

7.66e-05597231491600
Pubmed

Instruction of naive CD4+ T-cell fate to T-bet expression and T helper 1 development: roles of T-cell receptor-mediated signals.

IL18 STAT1

7.66e-05597217490433
Pubmed

Jak/STAT signaling pathway regulates nox1 and nox4-based NADPH oxidase in human aortic smooth muscle cells.

NOX4 STAT1

7.66e-05597219834108
Pubmed

Role of ZBP-89 in human globin gene regulation and erythroid differentiation.

ZNF148 TRRAP

7.66e-05597221828133
Pubmed

Gene expression profiling of preplate neurons destined for the subplate: genes involved in transcription, axon extension, neurotransmitter regulation, steroid hormone signaling, and neuronal survival.

SLC1A1 RYR1

7.66e-05597219398467
Pubmed

Positive role of promyelocytic leukemia protein in type I interferon response and its regulation by human cytomegalovirus.

STAT1 HDAC2

7.66e-05597225812002
Pubmed

Inhibition of HDAC enhances STAT acetylation, blocks NF-κB, and suppresses the renal inflammation and fibrosis in Npr1 haplotype male mice.

STAT1 HDAC2

7.66e-05597228566502
Pubmed

Endocytosis of the glucose transporter GLUT8 is mediated by interaction of a dileucine motif with the beta2-adaptin subunit of the AP-2 adaptor complex.

AP1B1 AP2B1

7.66e-05597216723738
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

MCMBP ZNF148 MCM4 XPO1 TRRAP DDX5 CCNB1 AP1B1 AP2B1 VPS35 EIF4G2 ZNF638 HDAC2

8.65e-051335971329229926
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

TOM1L2 GFRAL PKD1L1 RAET1E NXPE3 SERPINA10 UGT3A2 SLAMF7 GMPPB ADAMTSL4 ADGRA3

9.62e-05985971112975309
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

IL18 COMT MCM4 PSMD5 XPO1 TRRAP STAT1 DDX5 AP2B1 VPS35 EIF4G2 ZNF638 GMPPB

9.89e-051353971329467282
Pubmed

Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.

PSMD5 XPO1 FAN1 ATAD3B

1.06e-048797417148452
Pubmed

Association study of 69 genes in the ret pathway identifies low-penetrance loci in sporadic medullary thyroid carcinoma.

COMT STAT1

1.15e-04697217909067
Pubmed

Clathrin.

AP1B1 AP2B1

1.15e-04697210966473
Pubmed

Frontline: absence of functional STAT4 activation despite detectable tyrosine phosphorylation induced by murine IFN-alpha.

IL18 STAT1

1.15e-04697215307169
Pubmed

Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene.

CITED2 HDAC2

1.15e-04697214633989
Pubmed

A common haplotype in NAPEPLD is associated with severe obesity in a Norwegian population-based cohort (the HUNT study).

IL18 CNR1

1.15e-04697220885390
Pubmed

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.

MCMBP XPO1 DDX5 VPS35 EIF4G2 HDAC2

1.16e-0427197625737280
Pubmed

Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development.

PSMD5 XPO1 AP1B1 VPS35

1.21e-049097428978906
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

CACNA1E TRIO ATAD3B AP1B1 AP2B1 TLN2

1.41e-0428197628706196
Pubmed

Identification and characterization of a novel component of the human minichromosome maintenance complex.

MCMBP MCM4

1.60e-04797217296731
Pubmed

Sumoylation of p68 and p72 RNA helicases affects protein stability and transactivation potential.

DDX5 HDAC2

1.60e-04797219995069
Pubmed

Nox4 - RyR1 - Nox2: Regulators of micro-domain signaling in skeletal muscle.

NOX4 RYR1

1.60e-04797232506037
Pubmed

Identification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gamma.

MCM4 STAT1

1.60e-04797211248027
Pubmed

NF-kappaB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK.

NFE2L2 HDAC2

1.60e-04797218241676
Pubmed

Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor.

XPO1 AP2B1

1.60e-04797216314522
Pubmed

Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow.

NFE2L2 HDAC2

1.60e-04797222308472
Pubmed

MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1.

XPO1 DDX5 AP1B1 AP2B1 VPS35

1.62e-0418297530711629
Pubmed

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.

COMT MCM4 PSMD5 XPO1 DDX5 AP2B1 FDFT1 VPS35 EIF4G2

1.64e-0470797919738201
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

MCMBP TRIO MCM4 XPO1 IDH3A STAT1 DDX5 VPS35 EIF4G2 CD47 TLN2 FGD5 ADGRA3

1.65e-041425971330948266
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1E TRPM7 RYR1

1.65e-043897330786075
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

TOM1L2 TRIO INPP4A XPO1 IDH3A DDX5 ATAD3B AP1B1 AP2B1 VPS35 EIF4G2 OSBPL6 TLN2

1.72e-041431971337142655
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

MCMBP COMT XPO1 IDH3A ATAD3B AP1B1 AP2B1 ETHE1 VPS35 HDAC2

1.73e-04878971037223481
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

TRIO DDX5 EHD2 AP2B1 EIF4G2 HDAC2

1.93e-0429897630737378
Pubmed

p21WAF1/CIP1 regulates the p300 sumoylation motif CRD1 through a C-terminal domain independently of cyclin/CDK binding.

CCNB1 HDAC2

2.13e-04897216082198
Pubmed

The effect of gluten-free diet on Th1-Th2-Th3-associated intestinal immune responses in celiac disease.

IL18 STAT1

2.13e-04897221288140
Pubmed

A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4.

AP1B1 AP2B1

2.13e-0489729811611
Pubmed

Pleiotropic effects of p300-mediated acetylation on p68 and p72 RNA helicase.

DDX5 HDAC2

2.13e-04897220663877
Pubmed

A bifunctional regulatory element in human somatic Wee1 mediates cyclin A/Cdk2 binding and Crm1-dependent nuclear export.

XPO1 CCNB1

2.13e-04897219858290
Pubmed

In vitro nuclear interactome of the HIV-1 Tat protein.

XPO1 TRRAP DDX5 ZNF638 HDAC2

2.23e-0419597519454010
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

ZNF148 MCM4 XPO1 TRRAP STAT1 DDX5 CCNB1 AP1B1 AP2B1 EIF4G2 HDAC2

2.57e-041103971134189442
Pubmed

Clint: a novel clathrin-binding ENTH-domain protein at the Golgi.

AP1B1 AP2B1

2.74e-04997212429846
Pubmed

The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation.

MCM4 CCNB1

2.74e-04997222157815
Pubmed

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells.

EZH1 HDAC2

2.74e-04997220075857
Pubmed

Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress.

IDH3A STAT1 ATAD3B AP1B1 AP2B1 EIF4G2

2.98e-0432397624797263
InteractionAP1S1 interactions

COMT XPO1 STAT1 AP1B1 AP2B1

8.14e-0659945int:AP1S1
CytobandEnsembl 112 genes in cytogenetic band chr9q12

SPATA31A7 SPATA31A5

1.23e-048972chr9q12
Cytoband14q32.13

SERPINA11 SERPINA10

5.89e-041797214q32.13
Cytoband9p13.1

SPATA31A3 SPATA31A1

1.18e-03249729p13.1
Cytoband3p21.31

TOPAZ1 LRRC2 GMPPB

1.27e-031009733p21.31
Cytoband4p15.2

ZCCHC4 ADGRA3

1.61e-03289724p15.2
CytobandEnsembl 112 genes in cytogenetic band chr3p21

TOPAZ1 LRRC2 DNAH1 GMPPB

4.62e-03316974chr3p21
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#3_top-relative-expression-ranked_500

AVPR1A NEB ENTPD1 CD47

1.08e-0532924gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k3
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_Captopr_top-relative-expression-ranked_1000

IL13RA1 COMT AVPR1A NOX4 NDRG2 SLC1A1 STAT1 NFE2L2 ETHE1 ENTPD1 CD47 OSBPL6 UGT3A2

3.00e-057789213gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#1_top-relative-expression-ranked_1000

AVPR1A NEB ENTPD1 CD47

7.06e-0551924gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k1
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MCM4 RYR1 NMU CCNB1 FAT2 OTOGL

2.34e-061759769142ed8ca2f1c0c518deb21988221406f62fe38c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRID1 NEB DNAH1 OTOGL TLN2 HYDIN

3.13e-061849762cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRID1 NEB DNAH1 OTOGL TLN2 HYDIN

3.13e-06184976ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRID1 NEB DNAH1 OTOGL TLN2 HYDIN

3.13e-061849762b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellBAL-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

IL13RA1 IL18 NDRG2 DDX5 CITED2 ENTPD1

4.91e-06199976da180aaa53f995183522da0f2321bf0c0c8ee6ec
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SDK2 IL18 AVPR1A DEPDC5 UGT3A2

1.21e-051369757cd22169fb71c6caf9feb203ad98be8480a54fba
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RYR1 QRFPR SLC24A4 CFAP61 HYDIN

1.54e-051439755fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal|GW19 / Sample Type, Dataset, Time_group, and Cell type.

DDX5 EIF4G2 CNR1 HDAC2

2.08e-0574974a50df7f4f7847b8aeff3fc6d521a69b50e05c719
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR1 DNAH1 SLC24A4 SERPINA10 HYDIN

2.57e-0515997500a157d033627d0e65c3fbd38d652c4cf56b47f6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1E NOX4 SLC1A1 OTOGL OSBPL6

3.84e-051739758888434641ea554a9b62c436e87920378eef29cd
ToppCellAT1-AT2_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 LRRC2 SLC1A1 EHD2 CTSE

4.06e-051759759a95ab5c361ebaa8747983c5a0d69025682a19ad
ToppCell3'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL13RA1 RAET1E NMU SERPINA11 CFAP61

4.52e-05179975906555ce2ca264a0215b120c7ff7c9b411de6a34
ToppCellAT1-AT2_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 SLC1A1 NMU EHD2 CTSE

4.76e-05181975ca23ce4f2c7b684d8ddd0e8619b3b696023d75e3
ToppCellRV|World / Chamber and Cluster_Paper

TRPM7 LRRC2 SPHKAP TLN2 CFAP61

4.76e-05181975bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3AP1 NOX4 SERPINA11 ADGRA3 KLB

5.02e-05183975d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NDRG2 NMU ENTPD1 SLAMF7 CTSE

5.02e-05183975bd78e5c2670e67b4363078e3ca5a5b7081d24b7e
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NDRG2 NMU ENTPD1 SLAMF7 CTSE

5.02e-05183975d1bf3abf42eb9d7facf775becf1338d1faadd647
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL13RA1 IL18 NDRG2 FDFT1 ENTPD1

5.15e-051849751c56378b3888c46258d446b47de4d6282fe74b0d
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL13RA1 IL18 NDRG2 FDFT1 ENTPD1

5.15e-05184975a45980306c4e697a2703bed72a7b48fb23d942f4
ToppCellfacs-GAT-Fat-3m|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 DDX5 AP1B1 VPS35 EIF4G2

5.99e-051909751d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MCM4 RYR1 NMU CCNB1 FAT2

6.15e-051919750f9443da0f73d07456142fae08b2dc92a5b7b592
ToppCellCOVID-19-Myeloid-DC2|COVID-19 / Condition, Lineage and Cell class

IL13RA1 SDK2 IL18 NDRG2 ENTPD1

6.15e-051919751304ab7b5713f29f3966ffc020ea1b52e8e2f375
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 SLC1A1 STAT1 HYDIN ABCG5

6.46e-05193975ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PIK3AP1 IL13RA1 AP1B1 ENTPD1 TLN2

6.46e-05193975b52d5661edff83ac4c5fe2bf89d6672016bb827b
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX5 AP1B1 VPS35 ENTPD1 EIF4G2

6.61e-0519497550c5fc349533281a426bc7227a8ea9eca8d11985
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL13RA1 IL18 NDRG2 RYR1 ENTPD1

6.61e-05194975b16ed97eb6b7b7a220e943474c0d85c141b6e3a5
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL13RA1 IL18 NDRG2 RYR1 ENTPD1

6.61e-051949752210f0755882d8f04edb4c109fb17c3f9149f6f7
ToppCellBronchial_Brush-Immune-Dendritic_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

NDRG2 DDX5 NFE2L2 ENTPD1 SLAMF7

6.61e-05194975dbcc00940538efc0f89f074dbe822c50efa5ad8e
ToppCellfacs-Brain_Myeloid-Cortex-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX5 AP1B1 VPS35 ENTPD1 EIF4G2

6.61e-051949751662b110f84584e75150df0ac970e7df82f26e7e
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX5 AP1B1 VPS35 ENTPD1 EIF4G2

6.61e-05194975b31d6361fa939a92a4a3dc63c209ecd3eb514e6a
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL13RA1 SDK2 IL18 NDRG2 ENTPD1

6.78e-051959757bb3bdfb8caaae357b1f7841d8d00936c4373dfe
ToppCellmetastatic_Brain-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

IL13RA1 NDRG2 NFE2L2 ETHE1 ENTPD1

6.78e-0519597579fd13a7dd9f07f86bcab280c0be1899a692fab2
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL13RA1 SDK2 IL18 NDRG2 ENTPD1

6.78e-05195975d579150d176e6bd81004b5146de4901ca13a3c3e
ToppCellCOVID-19_Severe-cDC|COVID-19_Severe / disease group, cell group and cell class

IL13RA1 IL18 NDRG2 RYR1 ETHE1

6.78e-051959756419090b19de7b5d5140eaecf231860273da2c0d
ToppCellMild/Remission-Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

INPP4A NXPE3 ENTPD1 SLAMF7 GMPPB

6.78e-0519597552bdd609253613b7db75dccbc1c01c05e8d73f79
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A3 SLC1A1 EHD2 CD47 CTSE

6.94e-051969756731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

COMT FDFT1 ETHE1 FGD5 ADAMTSL4

6.94e-05196975fe90501010128b72e6711c567cb04b012f1520a4
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A3 SLC1A1 EHD2 CD47 CTSE

6.94e-051969756856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCellMild/Remission-Plasmablast|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

INPP4A NXPE3 ENTPD1 SLAMF7 GMPPB

6.94e-05196975dcf0a804a79a05454658498d1f87320c7e079219
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A3 SLC1A1 EHD2 CD47 CTSE

7.11e-05197975c9c968e223e7814cd8d22975d849a31b7e0af7aa
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A3 SLC1A1 EHD2 CD47 CTSE

7.11e-05197975734b8db5bb4917c9ce92ed342fe6c22b64b0d3c5
ToppCellASK440-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

COL4A3 IL18 SLC1A1 EHD2 CD47

7.11e-05197975782449c522c9e16e72bf999a73090688a3aefe06
ToppCellASK428-Epithelial-Type_1|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

COL4A3 SLC1A1 EHD2 CD47 CTSE

7.11e-051979759ae6661c307791c3f0ecd3d378e3d917565e5498
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A3 SLC1A1 EHD2 CD47 CTSE

7.11e-05197975e344455e62b3fe94bb242dc0db58d19a1d3878c7
ToppCellHealthy-cDC|World / disease group, cell group and cell class

IL13RA1 IL18 NDRG2 RYR1 ETHE1

7.28e-051989758976f8d26cb7ff79f74def138c4bbbb0bc2eaf00
ToppCell(0)_Myeloid-(01)_Dendritic_cell-(010)_cDC|(01)_Dendritic_cell / immune cells in Peripheral Blood (logTPM normalization)

IL13RA1 IL18 NDRG2 ETHE1 ENTPD1

7.28e-051989754abc274edac40f8836255fac2371ffd98a32cccd
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_1|356C / Donor, Lineage, Cell class and subclass (all cells)

IL18 MCM4 NDRG2 CCNB1 ENTPD1

7.28e-05198975f801157468e59b5d049f703feadc9bb0f11e85cc
ToppCellCOVID-19_Severe-cDC|World / disease group, cell group and cell class

IL13RA1 IL18 NDRG2 RYR1 ETHE1

7.28e-05198975c452334249f047265ae89dcabe7de446d968cae6
ToppCellASK428-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

COL4A3 SLC1A1 EHD2 CD47 CTSE

7.28e-051989750047a9ef7684230ac5179efea94461480e90bdaf
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

PIK3AP1 IL18 RYR1 AP1B1 TLN2

7.64e-05200975a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

PIK3AP1 IL18 RYR1 AP1B1 TLN2

7.64e-05200975dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

PIK3AP1 IL18 RYR1 AP1B1 TLN2

7.64e-052009753bba5219453322198e8fdb0921d5f8c403598751
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

PIK3AP1 IL18 RYR1 AP1B1 TLN2

7.64e-0520097521bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCellcontrol-cDC|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IL13RA1 IL18 TRIO NDRG2 RYR1

7.64e-052009754a6d17a4225be38537d3dd8a39512051f597f4e0
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

PIK3AP1 IL18 RYR1 AP1B1 TLN2

7.64e-05200975a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

PIK3AP1 IL18 RYR1 AP1B1 TLN2

7.64e-0520097533036d21c1c82109284473a515c4f890b33fdd5c
ToppCelldroplet-Bladder-nan-3m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ING2 SMC5 DNAH1 ADAMTSL4

1.33e-04119974018162114bc22a9780fded5887f1f78211851700
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_8|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL18 NDRG2 TLN2 ZNF763

2.55e-04141974737237db115721524c44ea4c55aed000e1b00ee5
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_8|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL18 NDRG2 TLN2 ZNF763

2.55e-04141974c14f84bc3921cafbce6fa7f7163ecf3cd9cdf073
ToppCelldroplet-Liver-Npc-21m-Epithelial-Hepatocyte_(Midlobular)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRID1 RAET1E NDRG2 ETHE1

2.70e-041439740cd332c128710291a39957d3da22953352f5c382
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

NOX4 NEB SPHKAP UGT3A2

2.70e-041439740118772a5bc7c48465e9b314be55203412e8d67c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 AVPR1A SERPINA11 NFE2L2

2.84e-041459749964d6d3769be2f35d86268fe044cecd1d5a1616
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

QRFPR SLC24A4 OTOGL SPHKAP

3.07e-04148974dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCelldroplet-Liver-Npc-18m-Epithelial-Hepatocyte_(Midlobular)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRID1 RAET1E DNAH1 ETHE1

3.32e-0415197486efabf27c264c856dca1cffacb16cef52e9863c
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Pde1a_(dSPN)-|Striatum / BrainAtlas - Mouse McCarroll V32

NMU SERPINA11 RTL9

3.68e-0464973def8cf047ec3ba3c40bb759d0910838df857f05b
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Pde1a_(dSPN)|Striatum / BrainAtlas - Mouse McCarroll V32

NMU SERPINA11 RTL9

3.68e-0464973cec968dc404934fa9888d445d7c4cd2df7f3cc7a
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINA11 SERPINA10 UGT3A2 ABCG5

3.75e-04156974e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellCOPD-Myeloid-DC_Langerhans|COPD / Disease state, Lineage and Cell class

IL18 NDRG2 ENTPD1 SERPINA10

3.94e-0415897471af1319eec34bf7bc9361ec9ef720c280ce97d1
ToppCell21-Trachea-Epithelial-Submucosal_gland_basal|Trachea / Age, Tissue, Lineage and Cell class

NOX4 SERPINA11 QRFPR FGD5

4.03e-041599744f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL13RA1 IL18 NDRG2 RYR1

4.03e-041599746115cb03c2ad08e4c1b65893d522f685ff0bc692
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL13RA1 IL18 NDRG2 RYR1

4.13e-04160974a90eb621481fd07a821495db07d1032e109fd386
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINA11 SERPINA10 UGT3A2 ABCG5

4.13e-04160974c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NXPE3 SLC24A4 ENTPD1 MSS51

4.23e-041619743a5f2877e3b29463a3a6da05009b0ab8747b4c47
ToppCellBAL-Mild-cDC_5|Mild / Compartment, Disease Groups and Clusters

PDE6A RYR1 CCNB1 ZCCHC4

4.23e-041619747a6e8ed0b5d999efce8945d8083ab01d71be9a92
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CACNA1E RGSL1 RYR1 SLC24A4

4.23e-04161974ebcd5066e82b7760b9da6adc02d11258d1309dab
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RGSL1 NEB OTOGL HYDIN

4.32e-04162974bf886e22ff2a20353499004b53f25fb9e6574896
ToppCelldroplet-Heart-nan-18m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REC114 RYR1 CCNB1 SLAMF7

4.32e-041629747f425a3983325a5a3ea33f812b15aa010cc55de0
ToppCelldroplet-Fat-Gat-18m-Hematologic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REC114 CCNB1 SPHKAP CTSE

4.63e-041659741e89154114327650df39befb2c56d0379ea6a221
ToppCelldroplet-Thymus-nan-21m-Myeloid-Plasma_cells_and_B_cells|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL13RA1 ENTPD1 SLAMF7 CTSE

4.63e-0416597421a82a975f550080b6674750b06212205cd16742
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SDK2 SMC5 FAN1 DEPDC5

4.74e-04166974f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCell356C-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

SLC24A4 SLAMF7 CTSE KLB

4.74e-04166974971ee6602a1e751f453f9d823295e63dadce62bf
ToppCell356C-Myeloid-Dendritic-cDC1|356C / Donor, Lineage, Cell class and subclass (all cells)

NDRG2 SLC24A4 ENTPD1 SLAMF7

4.74e-041669740590e404f45afce90e20f93f90a3def83949c66b
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL18 NDRG2 SLC24A4 SLAMF7

4.74e-04166974b1bebcbe17386cb102b11d551e62d46156ce0c68
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1E SDK2 NOX4 RYR1

4.85e-041679743edb0570e583bb527165bcd8a4c25a042054043b
ToppCellICU-NoSEP-Myeloid-cDC2|ICU-NoSEP / Disease, Lineage and Cell Type

IL13RA1 IL18 NDRG2 FAT2

4.85e-041679745b7b731944d888591279ef6167b3ae8cab3f6886
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL18 NDRG2 SLC24A4 SLAMF7

4.85e-04167974e44743b20a7435c579d8e999ddc4ca119d6753f2
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E CITED2 SLAMF7 CTSE

4.96e-0416897441da200bbff5c663c39f67c38d6d5f43b0ad9494
ToppCellSigmoid-Macrophage-Macrophage|Macrophage / Region, Cell class and subclass

NDRG2 AP1B1 ENTPD1 SLAMF7

4.96e-04168974bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E CITED2 SLAMF7 CTSE

4.96e-04168974a77259c13508f19186d7b0f80b34dc6d89497ab5
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDRG2 SERPINA11 SERPINA10 UGT3A2

4.96e-04168974b98af4043dfa5dfa4413e482879fad88de484675
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDRG2 SERPINA11 SERPINA10 UGT3A2

4.96e-04168974073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCellDendritic_Cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

IL13RA1 IL18 NDRG2 ENTPD1

4.96e-0416897433618e5dbcee31f30afacacc9f6046782c100fb3
ToppCelldroplet-Liver-HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDRG2 SERPINA11 SERPINA10 UGT3A2

5.07e-04169974f195467438c589f87224bde7da720dea072d110c
ToppCelldroplet-Liver-HEPATOCYTES-1m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDRG2 SERPINA11 SERPINA10 UGT3A2

5.07e-041699747785cab967a33560830c394c918d6ce625103858
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH1 OSBPL6 CFAP61 HYDIN

5.07e-04169974fba841664939c771881ba97f14ef1df6635c04ff
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL18 RAET1E OTOGL SPHKAP

5.07e-041699740cece9b2bb1f58e465c20ec8735a4fc3c1021f03
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL18 RAET1E OTOGL SPHKAP

5.07e-041699746937c46b119d4ce382fc8c2fa5925ede5ae89c81
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH1 SLC24A4 RTL9 CFAP61

5.19e-04170974b535baeb4dbd644051cf992babb61add9eaae4e3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH1 SLC24A4 RTL9 CFAP61

5.19e-041709742477c9f29dbe27f172df699003971e828d6ab8c9
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IL18 FAT2 SLC24A4 SLAMF7

5.19e-041709743cbeea6bfa500928c413b1c6129f6dedc769cd1e
DrugMechlorethamine

NDRG2 NMU CCNB1 NFE2L2 CNR1 HDAC2

4.28e-0771926ctd:D008466
Diseasefocal epilepsy (implicated_via_orthology)

DEPDC5 CNR1

9.62e-062922DOID:2234 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

CACNA1E TRIO SLC1A1 SLC24A4 KCNA10 DEPDC5

1.25e-05163926DOID:1826 (implicated_via_orthology)
DiseaseLiver Cirrhosis

TRPM7 STAT1 NFE2L2 CNR1 HDAC2

1.82e-05103925C0023890
DiseaseFibrosis, Liver

TRPM7 STAT1 NFE2L2 CNR1 HDAC2

1.99e-05105925C0239946
Diseasechronic obstructive pulmonary disease (biomarker_via_orthology)

STAT1 NFE2L2 HDAC2

9.08e-0528923DOID:3083 (biomarker_via_orthology)
DiseaseMarijuana Abuse

COMT FDFT1 CNR1

1.12e-0430923C0024809
DiseaseMULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE

NEB RYR1

1.43e-046922C1854678
Diseasepulmonary emphysema (biomarker_via_orthology)

IL18 HDAC2

1.43e-046922DOID:9675 (biomarker_via_orthology)
Diseasebrain edema (implicated_via_orthology)

IL18 AVPR1A

1.43e-046922DOID:4724 (implicated_via_orthology)
DiseaseMental Depression

IL18 COMT GRID1 SLC1A1 CNR1 HDAC2

1.47e-04254926C0011570
DiseaseHeadache, glucose measurement

ZCCHC4 ZNF638

3.41e-049922EFO_0004468, HP_0002315
DiseaseCannabis Abuse

FDFT1 CNR1

4.26e-0410922C0006868
DiseaseCannabis-Related Disorder

FDFT1 CNR1

4.26e-0410922C0236735
DiseaseHashish Abuse

FDFT1 CNR1

4.26e-0410922C0018614
DiseaseSchizophrenia

IL18 COMT AVPR1A GRID1 TRRAP SLC1A1 VPS35 MSS51 CNR1 HDAC2

4.31e-048839210C0036341
DiseaseIntellectual Disability

CACNA1E TRIO INPP4A TRRAP AP1B1 FDFT1 ENTPD1

5.06e-04447927C3714756
DiseaseSitus Inversus

PKD1L1 CITED2

5.19e-0411922C0037221
DiseaseSeizures

CACNA1E TRRAP SLC1A1 FDFT1 CNR1

6.14e-04218925C0036572
Diseasepulmonary fibrosis (implicated_via_orthology)

STAT1 NFE2L2

6.22e-0412922DOID:3770 (implicated_via_orthology)
DiseaseCongenital muscular dystrophy

RYR1 GMPPB

6.22e-0412922cv:C0699743
DiseaseCongenital myopathy (disorder)

NEB RYR1

6.22e-0412922C0270960
DiseaseN-acetyltaurine measurement

EIF4G2 CNR1

7.33e-0413922EFO_0020023
DiseaseSkin Abnormalities

AP1B1 FDFT1

7.33e-0413922C0037268
Diseasehypertension (biomarker_via_orthology)

COMT AVPR1A NOX4 NFE2L2 EIF4G2

7.36e-04227925DOID:10763 (biomarker_via_orthology)
Diseasemean reticulocyte volume

MCM4 XPO1 NEB TRRAP CITED2 AP2B1 FDFT1 ZNF638 TLN2

8.77e-04799929EFO_0010701
Diseasemyocardial infarction (implicated_via_orthology)

AVPR1A RYR1 NFE2L2

1.16e-0366923DOID:5844 (implicated_via_orthology)
DiseaseCannabis Dependence

FDFT1 CNR1

1.27e-0317922C0006870
Diseasenon-alcoholic steatohepatitis (biomarker_via_orthology)

NOX4 NFE2L2

1.27e-0317922DOID:0080547 (biomarker_via_orthology)
DiseaseSchizophrenia

COMT SLC1A1

1.42e-0318922cv:C0036341
Diseaserenovascular hypertension (biomarker_via_orthology)

AVPR1A EIF4G2

1.59e-0319922DOID:1591 (biomarker_via_orthology)
DiseaseEndometrioma

SLC1A1 DDX5 CNR1 HDAC2

1.64e-03161924C0269102
DiseaseEndometriosis

SLC1A1 DDX5 CNR1 HDAC2

1.64e-03161924C0014175
DiseaseAttention Deficit Disorder

COMT CNR1

2.13e-0322922C0041671
DiseaseMinimal Brain Dysfunction

COMT CNR1

2.13e-0322922C1321905
DiseaseDepressive disorder

IL18 COMT GRID1 SLC1A1 CNR1

2.14e-03289925C0011581
DiseaseEpilepsy, Benign Psychomotor, Childhood

SLC1A1 CNR1

2.33e-0323922C0393672
DiseaseOvarian Serous Adenocarcinoma

TRPM7 TRRAP

2.33e-0323922C1335177
DiseaseEpilepsy, Lateral Temporal

SLC1A1 CNR1

2.33e-0323922C0393682
DiseaseQRS duration, response to sulfonylurea

ZNF638 UQCC1

2.33e-0323922EFO_0005055, EFO_0007922
DiseaseUncinate Epilepsy

SLC1A1 CNR1

2.33e-0323922C0014558
DiseaseEpilepsy, Temporal Lobe

SLC1A1 CNR1

2.33e-0323922C0014556
DiseaseAttention deficit hyperactivity disorder

COMT CNR1

2.54e-0324922C1263846
Diseasebreast cancer (is_marker_for)

IL18 COMT STAT1 CCNB1

2.72e-03185924DOID:1612 (is_marker_for)
Disease3-hydroxybutyrate measurement

FDFT1 SERPINA10

2.75e-0325922EFO_0010982
DiseaseLiver Cirrhosis, Experimental

IL18 NOX4 SMC5 NDRG2 NFE2L2 CTSE ABCG5 CNR1

2.90e-03774928C0023893
Diseaseobesity (is_implicated_in)

COMT NMU CNR1

2.92e-0391923DOID:9970 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
ELQCQLFPNISAEDM

BTNL10

51

A8MVZ5
TIQCMIESFPEIFQR

CEACAM18

201

A8MTB9
NFVKMVPFNTCTLEQ

CFAP61

436

Q8NHU2
FPDVVNCMQTDNLEL

AP2B1

51

P63010
PRALQCAAFNSQEFM

ADAMTSL4

386

Q6UY14
IFQLACMDPADDGQF

CACNA1E

1946

Q15878
RFTTMPFLFCNVNDV

COL4A3

1496

Q01955
RQVVFEGDSLPFQCM

ADGRA3

251

Q8IWK6
TFLNRFMCAQLPNQV

EHD2

131

Q9NZN4
FPDVVNCMQTDNLEL

AP1B1

51

Q10567
NLLSNAANPVEFMCQ

PIK3AP1

271

Q6ZUJ8
MCRDDPTYFAQQQKE

GKN3P

136

P0CG01
EFNVFTFVNLPMCRE

SLC24A4

606

Q8NFF2
DPSTLQVEMFCQREA

RAET1E

116

Q8TD07
CLMDQNFPAFVEEVE

REC114

241

Q7Z4M0
FFCIPVTMLQNISDN

QRFPR

96

Q96P65
APQVFTQALECMRSE

INPP4A

921

Q96PE3
QQVFEEFICQRLMQG

DEPDC5

796

O75140
IPEMQEAFFQCQVCA

MCM4

296

P33991
QPQASNALEELCFMI

NMU

71

P48645
PQEMFQRMEDTFRFC

MSS51

91

Q4VC12
VLNSDVICDFPFQAM

GMPPB

106

Q9Y5P6
VICDFPFQAMVQFHR

GMPPB

111

Q9Y5P6
AVECANLNVMPDVTF

CTSE

311

P14091
FPANVMDVIARQNFT

DDX5

101

P17844
RNQSVFNFCAIPQVM

FDFT1

281

P37268
QPMFEEVNCTGSIRQ

FAT2

561

Q9NYQ8
ICNIMNAPAEDFFAF

PDE6A

356

P16499
FDDCMQLLAQTFPFV

NFE2L2

116

Q16236
QIVPFENDCMEDFVT

FGD5

326

Q6ZNL6
FVSLMDNPIDNAQCE

LRRC2

311

Q9BYS8
CTKRFEMTLPFQQFE

ENTPD1

301

P49961
DNFMQAFLNVLDQCP

EIF4G2

616

P78344
APNFTDMQANCVDIS

OSBPL6

291

Q9BZF3
RQMELHSQCFQDPAE

ING2

116

Q9H160
EFERNVENTSCFMVP

IL13RA1

286

P78552
FVKICMEEPRFQANF

NOX4

266

Q9NPH5
MVNESFENTQRVRPC

PLA2G4E

231

Q3MJ16
VVCPSKTDFFRNIMN

KCNA10

291

Q16322
INPDCAAITQRMVDF

COMT

141

P21964
EDPCMFAQRVVQANA

DNAH1

366

Q9P2D7
TVSIIDRFMQNNCVP

CCNB1

226

P14635
CLNMVQDPSQFDVLV

IDH3A

236

P50213
TPQIMQNYQCIFEAT

HYDIN

3436

Q4G0P3
QNIPFNIAQMLAFCD

GFRAL

176

Q6UXV0
TNPMCAFTQGIQFIE

ABCG5

596

Q9H222
ECFMVLNPSQQLAIA

CNR1

106

P21554
QIDFAVPANMRCGVQ

ETHE1

236

O95571
LMERNPEFIFACSQA

MAN2C1

286

Q9NTJ4
NPFQAVQEACDLMTQ

GRID1

71

Q9ULK0
EPNRSENTMDIFKCQ

KLB

306

Q86Z14
TVVIPCFVTNMEAQN

CD47

36

Q08722
QMQRFNVGEDCPVFD

HDAC2

91

Q92769
MAAEPVEDNCINFVA

IL18

1

Q14116
VPDDTGMFQCFARNA

SDK2

371

Q58EX2
MINCEEFANRFQEPA

RYR1

4121

P21817
SDNFMNPVLNCSLEV

PKD1L1

286

Q8TDX9
IRNMFPENLVQACFQ

SLC1A1

146

P43005
QMEFPCNINVFITSE

MCMBP

496

Q9BTE3
STPECREDQFMIQVR

OTOGL

1981

Q3ZCN5
FMDGIPDVFRNACQA

FAN1

851

Q9Y2M0
EENVEPQNKQMAFCR

RTL9

16

Q8NET4
FFQGQLSPEEMLQCD

RGSL1

701

A5PLK6
LQNQRMPCQIGFVED

SPHKAP

61

Q2M3C7
QLIQSSFVVERQPCM

STAT1

311

P42224
KSCFQPLFQFEDMQE

NDRG2

76

Q9UN36
FKMRQFNDPDNITEC

NXPE3

336

Q969Y0
LFNEMSNVCPIQRET

SPATA31A6

446

Q5VVP1
LFNEMSNVCPIQRET

SPATA31A7

446

Q8IWB4
NPEFRVQFQDMCATI

SNF8

61

Q96H20
PEQFDCAINSRIDVM

ATAD3B

456

Q5T9A4
NEFDFMTDFVCKQQP

CITED2

251

Q99967
LFNEMSNVCPIQRET

SPATA31A3

446

Q5VYP0
EFSQIFQLCQFVMEN

XPO1

201

O14980
FMEFVLQVPERQVDC

nan

211

Q6ZTK2
LFNEMSNVCPIQRET

SPATA31A1

446

Q5TZJ5
LFNEMSNVCPIQRET

SPATA31A5

446

Q5VU36
QVVDCLPEFSQDTFM

SERPINA11

191

Q86U17
IANQCMDPSLQVQLF

VPS35

706

Q96QK1
PLQQNFMVEDETVLC

EZH1

116

Q92800
MTFICVARNPVSRNF

SLAMF7

191

Q9NQ25
EEFFLRCQMPDTFNS

UQCC1

131

Q9NVA1
ADLAVAFFQVLPQMC

AVPR1A

96

P37288
FDTECVPMNFRNASQ

SERPINA10

186

Q9UK55
RNADFMVGECQFAVP

TOPAZ1

1011

Q8N9V7
ESRICQFFPSFQMLD

ZCCHC4

321

Q9H5U6
PIQFARANQAIQMAC

TLN2

1466

Q9Y4G6
FFGNLAVMDSPQQIC

PSMD5

276

Q16401
EKPFQCSQCDMRFIQ

ZNF148

196

Q9UQR1
TCQNPEIFKEMNNAF

UGT3A2

306

Q3SY77
QQCNPRDGFDMFAQT

TOM1L2

376

Q6ZVM7
MDPVACEDVAVNFTQ

ZNF763

1

Q0D2J5
NRCPFRVVDEINQGM

SMC5

1011

Q8IY18
QALSEASFQDPCVEM

ZNF79

121

Q15937
SMIAVARCFAQPNFK

TRRAP

3751

Q9Y4A5
NNFQNITEEIPMEVF

TRPM7

801

Q96QT4
NVICNSMFPVEDVFR

ZNF638

256

Q14966
MFTVVGFVCQDPAQR

TTLL5

391

Q6EMB2
QNMFLVFRAATDQCP

TRIO

2586

O75962
ETPCFEVANARMNAD

NEB

291

P20929