Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP hydrolysis activity	HSP90B1 ERCC6L ABCA13 ATP8A2 CHD3 CHD4 DDX55 DDX46 ATP8A1 CHD5 MTREX DNAH5 ATP4A DYNC1H1	1.51e-05	441	162	14	GO:0016887
GeneOntologyMolecularFunction	ATP-dependent activity	HSP90B1 ERCC6L MYO7B ABCA13 ATP8A2 CHD3 CHD4 DDX55 DDX46 ATP8A1 CHD5 MYO3B MTREX DNAH5 ATP4A DYNC1H1	4.14e-05	614	162	16	GO:0140657
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	ERCC6L CHD3 CHD4 CHD5	2.24e-04	37	162	4	GO:0140658
GeneOntologyMolecularFunction	helicase activity	ERCC6L CHD3 CHD4 DDX55 DDX46 CHD5 MTREX	3.11e-04	158	162	7	GO:0004386
GeneOntologyMolecularFunction	cytoskeletal regulatory protein binding	CTTNBP2 MAP1B	6.44e-04	5	162	2	GO:0005519
GeneOntologyMolecularFunction	phosphatidylserine flippase activity	ATP8A2 ATP8A1	6.44e-04	5	162	2	GO:0140346
GeneOntologyMolecularFunction	cytoskeleton-nuclear membrane anchor activity	SYNE1 SYNE2	6.44e-04	5	162	2	GO:0140444
GeneOntologyCellularComponent	sarcolemma	CACNA1D SGCG ITGA7 RYR3 SLC8A3 CLCN1 SVIL UTRN	1.26e-04	190	163	8	GO:0042383
GeneOntologyCellularComponent	NuRD complex	CHD3 CHD4 CHD5	2.92e-04	17	163	3	GO:0016581
GeneOntologyCellularComponent	FAR/SIN/STRIPAK complex	CTTNBP2 CTTNBP2NL STRN	2.92e-04	17	163	3	GO:0090443
GeneOntologyCellularComponent	CHD-type complex	CHD3 CHD4 CHD5	2.92e-04	17	163	3	GO:0090545
Domain	CHD_N	CHD3 CHD4 CHD5	6.65e-07	3	164	3	IPR012958
Domain	CHD_C2	CHD3 CHD4 CHD5	6.65e-07	3	164	3	IPR012957
Domain	CHDCT2	CHD3 CHD4 CHD5	6.65e-07	3	164	3	PF08074
Domain	CHDNT	CHD3 CHD4 CHD5	6.65e-07	3	164	3	PF08073
Domain	DUF1086	CHD3 CHD4 CHD5	6.65e-07	3	164	3	IPR009462
Domain	DUF1087	CHD3 CHD4 CHD5	6.65e-07	3	164	3	IPR009463
Domain	DUF1087	CHD3 CHD4 CHD5	6.65e-07	3	164	3	PF06465
Domain	DUF1086	CHD3 CHD4 CHD5	6.65e-07	3	164	3	PF06461
Domain	DUF1087	CHD3 CHD4 CHD5	6.65e-07	3	164	3	SM01147
Domain	DUF1086	CHD3 CHD4 CHD5	6.65e-07	3	164	3	SM01146
Domain	PolyA	PABPC4 PABPC1 PABPC3	6.56e-06	5	164	3	SM00517
Domain	-	PABPC4 PABPC1 PABPC3	6.56e-06	5	164	3	1.10.1900.10
Domain	PABP	PABPC4 PABPC1 PABPC3	6.56e-06	5	164	3	PF00658
Domain	PABP_1234	PABPC4 PABPC1 PABPC3	6.56e-06	5	164	3	IPR006515
Domain	PABC	PABPC4 PABPC1 PABPC3	6.56e-06	5	164	3	PS51309
Domain	PABP_HYD	PABPC4 PABPC1 PABPC3	6.56e-06	5	164	3	IPR002004
Domain	Helicase_C	ERCC6L CHD3 CHD4 DDX55 DDX46 CHD5 MTREX	4.42e-05	107	164	7	PF00271
Domain	HELICc	ERCC6L CHD3 CHD4 DDX55 DDX46 CHD5 MTREX	4.42e-05	107	164	7	SM00490
Domain	Helicase_C	ERCC6L CHD3 CHD4 DDX55 DDX46 CHD5 MTREX	4.69e-05	108	164	7	IPR001650
Domain	HELICASE_CTER	ERCC6L CHD3 CHD4 DDX55 DDX46 CHD5 MTREX	4.98e-05	109	164	7	PS51194
Domain	HELICASE_ATP_BIND_1	ERCC6L CHD3 CHD4 DDX55 DDX46 CHD5 MTREX	4.98e-05	109	164	7	PS51192
Domain	DEXDc	ERCC6L CHD3 CHD4 DDX55 DDX46 CHD5 MTREX	4.98e-05	109	164	7	SM00487
Domain	Helicase_ATP-bd	ERCC6L CHD3 CHD4 DDX55 DDX46 CHD5 MTREX	5.28e-05	110	164	7	IPR014001
Domain	ZF_SWIM	ZSWIM8 ZSWIM5 ZSWIM6	5.37e-05	9	164	3	PS50966
Domain	Znf_SWIM	ZSWIM8 ZSWIM5 ZSWIM6	5.37e-05	9	164	3	IPR007527
Domain	SNF2_N	ERCC6L CHD3 CHD4 CHD5	1.70e-04	32	164	4	IPR000330
Domain	SNF2_N	ERCC6L CHD3 CHD4 CHD5	1.70e-04	32	164	4	PF00176
Domain	SPEC	SYNE1 MCF2L2 SYNE2 UTRN	1.70e-04	32	164	4	SM00150
Domain	Spectrin/alpha-actinin	SYNE1 MCF2L2 SYNE2 UTRN	1.70e-04	32	164	4	IPR018159
Domain	ARM-type_fold	GBF1 TOGARAM2 FRYL MEI1 TRRAP RYR3 FOCAD URB1 ATXN10 PRKDC FMNL1	2.08e-04	339	164	11	IPR016024
Domain	Znf_FYVE_PHD	FYCO1 CHD3 CHD4 MTMR4 PHF3 CHD5 KDM2B	3.22e-04	147	164	7	IPR011011
Domain	CH	CFAP47 SYNE1 SYNE2 LIMCH1 UTRN	3.75e-04	70	164	5	PF00307
Domain	-	CFAP47 SYNE1 SYNE2 LIMCH1 UTRN	4.01e-04	71	164	5	1.10.418.10
Domain	KASH	SYNE1 SYNE2	4.55e-04	4	164	2	IPR012315
Domain	Cortactin-binding_p2_N	CTTNBP2 CTTNBP2NL	4.55e-04	4	164	2	IPR019131
Domain	SHR-BD	VPS13A VPS13B	4.55e-04	4	164	2	IPR009543
Domain	KASH	SYNE1 SYNE2	4.55e-04	4	164	2	PS51049
Domain	KASH	SYNE1 SYNE2	4.55e-04	4	164	2	SM01249
Domain	KASH	SYNE1 SYNE2	4.55e-04	4	164	2	PF10541
Domain	VPS13_C	VPS13A VPS13B	4.55e-04	4	164	2	PF16909
Domain	VPS13_C	VPS13A VPS13B	4.55e-04	4	164	2	IPR031645
Domain	CortBP2	CTTNBP2 CTTNBP2NL	4.55e-04	4	164	2	PF09727
Domain	SHR-BD	VPS13A VPS13B	4.55e-04	4	164	2	PF06650
Domain	CH	CFAP47 SYNE1 SYNE2 LIMCH1 UTRN	4.56e-04	73	164	5	PS50021
Domain	Ion_trans_dom	CACNA1D KCNH8 TPTE2 TRPM2 RYR3 CNGB3	5.11e-04	114	164	6	IPR005821
Domain	Ion_trans	CACNA1D KCNH8 TPTE2 TRPM2 RYR3 CNGB3	5.11e-04	114	164	6	PF00520
Domain	CH-domain	CFAP47 SYNE1 SYNE2 LIMCH1 UTRN	5.16e-04	75	164	5	IPR001715
Domain	TPR_REGION	ERCC6L NAA25 VPS13A PEX5 PRKDC TTC38 EDRF1	6.45e-04	165	164	7	PS50293
Domain	TPR	ERCC6L NAA25 VPS13A PEX5 PRKDC TTC38 EDRF1	6.45e-04	165	164	7	PS50005
Domain	Znf_PHD-finger	CHD3 CHD4 PHF3 CHD5 KDM2B	6.56e-04	79	164	5	IPR019787
Domain	Autophagy-rel_C	VPS13A VPS13B	7.53e-04	5	164	2	IPR015412
Domain	ATG_C	VPS13A VPS13B	7.53e-04	5	164	2	PF09333
Domain	Spectrin	SYNE1 SYNE2 UTRN	1.03e-03	23	164	3	PF00435
Domain	ACTININ_2	SYNE1 SYNE2 UTRN	1.03e-03	23	164	3	PS00020
Domain	ACTININ_1	SYNE1 SYNE2 UTRN	1.03e-03	23	164	3	PS00019
Domain	RRM_1	PABPC4 PABPC1 PABPC3	1.03e-03	23	164	3	SM00361
Domain	Actinin_actin-bd_CS	SYNE1 SYNE2 UTRN	1.03e-03	23	164	3	IPR001589
Domain	RRM_dom_euk	PABPC4 PABPC1 PABPC3	1.03e-03	23	164	3	IPR003954
Domain	FAT	TRRAP PRKDC	1.12e-03	6	164	2	PS51189
Domain	FATC	TRRAP PRKDC	1.12e-03	6	164	2	PS51190
Domain	FAT	TRRAP PRKDC	1.12e-03	6	164	2	PF02259
Domain	PIK-rel_kinase_FAT	TRRAP PRKDC	1.12e-03	6	164	2	IPR003151
Domain	FATC_dom	TRRAP PRKDC	1.12e-03	6	164	2	IPR003152
Domain	PIK_FAT	TRRAP PRKDC	1.12e-03	6	164	2	IPR014009
Domain	FATC	TRRAP PRKDC	1.12e-03	6	164	2	SM01343
Domain	PHD	CHD3 CHD4 PHF3 CHD5 KDM2B	1.13e-03	89	164	5	SM00249
Domain	Chromo_domain	CHD3 CHD4 CHD5	1.17e-03	24	164	3	IPR023780
Domain	Znf_PHD	CHD3 CHD4 PHF3 CHD5 KDM2B	1.24e-03	91	164	5	IPR001965
Domain	Chromo	CHD3 CHD4 CHD5	1.49e-03	26	164	3	PF00385
Domain	ZF_PHD_2	CHD3 CHD4 PHF3 CHD5 KDM2B	1.51e-03	95	164	5	PS50016
Domain	ZF_PHD_1	CHD3 CHD4 PHF3 CHD5 KDM2B	1.58e-03	96	164	5	PS01359
Domain	CHROMO_1	CHD3 CHD4 CHD5	1.85e-03	28	164	3	PS00598
Domain	CHROMO_2	CHD3 CHD4 CHD5	1.85e-03	28	164	3	PS50013
Domain	Spectrin_repeat	SYNE1 SYNE2 UTRN	2.05e-03	29	164	3	IPR002017
Domain	Chorein_N	VPS13A VPS13B	2.07e-03	8	164	2	PF12624
Domain	DHC_N1	DNAH5 DYNC1H1	2.07e-03	8	164	2	PF08385
Domain	VPS13_N	VPS13A VPS13B	2.07e-03	8	164	2	IPR026854
Domain	Dynein_heavy_dom-1	DNAH5 DYNC1H1	2.07e-03	8	164	2	IPR013594
Domain	TPR-contain_dom	ERCC6L NAA25 VPS13A PEX5 PRKDC EDRF1	2.11e-03	150	164	6	IPR013026
Domain	Zinc_finger_PHD-type_CS	CHD3 CHD4 PHF3 CHD5	2.56e-03	65	164	4	IPR019786
Domain	CH	SYNE1 SYNE2 LIMCH1 UTRN	2.56e-03	65	164	4	SM00033
Domain	MYTH4	MYO7B PLEKHH1	2.65e-03	9	164	2	PS51016
Domain	MyTH4	MYO7B PLEKHH1	2.65e-03	9	164	2	SM00139
Domain	MyTH4_dom	MYO7B PLEKHH1	2.65e-03	9	164	2	IPR000857
Domain	MyTH4	MYO7B PLEKHH1	2.65e-03	9	164	2	PF00784
Domain	-	ATP8A2 ATP8A1 ATP4A	2.73e-03	32	164	3	3.40.1110.10
Domain	-	ATP8A2 ATP8A1 ATP4A	2.73e-03	32	164	3	2.70.150.10
Domain	Chromodomain-like	CHD3 CHD4 CHD5	2.73e-03	32	164	3	IPR016197
Domain	Chromo/shadow_dom	CHD3 CHD4 CHD5	2.99e-03	33	164	3	IPR000953
Domain	CHROMO	CHD3 CHD4 CHD5	2.99e-03	33	164	3	SM00298
Domain	ATPase_P-typ_cyto_domN	ATP8A2 ATP8A1 ATP4A	3.54e-03	35	164	3	IPR023299
Domain	DNA/RNA_helicase_DEAH_CS	CHD3 CHD4 CHD5	3.54e-03	35	164	3	IPR002464
Domain	ATPase_P-typ_P_site	ATP8A2 ATP8A1 ATP4A	3.84e-03	36	164	3	IPR018303
Domain	P_typ_ATPase	ATP8A2 ATP8A1 ATP4A	3.84e-03	36	164	3	IPR001757
Domain	ATPASE_E1_E2	ATP8A2 ATP8A1 ATP4A	3.84e-03	36	164	3	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP8A2 ATP8A1 ATP4A	4.15e-03	37	164	3	IPR008250
Domain	E1-E2_ATPase	ATP8A2 ATP8A1 ATP4A	4.15e-03	37	164	3	PF00122
Domain	PHD	CHD3 CHD4 PHF3 CHD5	4.29e-03	75	164	4	PF00628
Domain	DEAH_ATP_HELICASE	CHD3 CHD4 CHD5	4.48e-03	38	164	3	PS00690
Domain	TPR-like_helical_dom	ERCC6L TRRAP NAA25 PEX5 PRKDC TTC38 EDRF1	4.58e-03	233	164	7	IPR011990
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TFEB CDK17 CDK18 ARHGAP32 GBF1 MAP1B ERCC6L MATK FRYL PABPC1 DENND2B CEP350 KIAA1671 USP8 MTMR4 PHF3 SVIL SYNE2 ANKRD17 LIMCH1 CKAP2 MTREX UTRN GARRE1 EDRF1 GOLGA4	7.44e-14	861	166	26	36931259
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ZSWIM8 MAP1B PABPC4 UTP14A FRYL CHD4 TRRAP PABPC1 URB1 DDX46 PHF3 SYNE2 ANKRD17 PRKDC MTREX IK UTRN CAPRIN1 DYNC1H1 HERC5 PTCD3	7.01e-12	653	166	21	22586326
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MAP9 HSP90B1 PCDHGB7 MAP1B PPRC1 ZSWIM5 RBBP8 SYNE1 PPP1R12B PABPC4 UTP14A CHD3 CHD4 DDX55 STK31 TRDN PABPC1 USP8 STRN COG1 PABPC3 CHD5 SYNE2 VPS13A FUNDC2 IRAK3 LIMCH1 PRKDC	2.61e-10	1442	166	28	35575683
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ZSWIM8 HSP90B1 REPS1 PPRC1 SYNE1 MCF2L2 PSMD4 CHD4 FRMD4B RYR3 CEP350 FOCAD PLEKHH1 USP8 NAA25 SERPINE2 COG1 ATXN10 PLCG1 PRKDC CKAP2 UTRN LCOR CAPRIN1 DYNC1H1	2.57e-09	1285	166	25	35914814
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	CTTNBP2 MAP1B SYNE1 PPP1R12B PABPC4 TRPM2 PSMD4 CTTNBP2NL PPP1R2 CEP350 STRN PRKDC MAPK3 MTREX UTRN CAPRIN1 DYNC1H1	2.65e-09	573	166	17	28330616
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	TCF3 MAP1B TRRAP CEP350 PRKDC MAPK3 UTRN DYNC1H1	3.25e-09	76	166	8	27542412
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	HSP90B1 MAP1B SYNE1 PABPC4 UTP14A CHD3 CHD4 TRRAP PABPC1 CEP350 KIAA1671 URB1 DDX46 SVIL SYNE2 PEX5 ATXN10 PRKDC MTREX IK UTRN DYNC1H1	4.33e-09	1024	166	22	24711643
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	CDK17 CDK18 CTTNBP2 GBF1 FRYL CTTNBP2NL KIAA1671 USP8 STRN VPS33B PRKDC MTREX UTRN GARRE1 FMNL1	4.52e-09	446	166	15	24255178
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ARHGAP32 HSP90B1 PPP1R12B TPTE2 WDR55 PSMD4 PPP1R2 CEP350 KIAA1671 MTMR4 VPS33B PDP1 SVIL SYNE2 VPS13A ATXN10 CKAP2 MAPK3 IK UTRN GOLGA4	3.36e-08	1049	166	21	27880917
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	GBF1 ERCC6L RBBP8 MATK CHD3 CHD4 TRRAP CTTNBP2NL PPP1R2 DDX46 PHF3 SVIL KDM2B ANKRD17 LIMCH1 PRKDC MAPK3 GOLGA4	3.76e-08	774	166	18	15302935
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	REPS1 SYNE1 PPP1R12B PABPC4 UTP14A WDR55 DDX55 TRRAP CTTNBP2NL GREB1L KIAA1671 STRN URB1 DDX46 GTF3C2 PHF3 KDM2B ANKRD17 LIMCH1 CKAP2 MTREX IK UTRN EDRF1 PTCD3	5.15e-08	1497	166	25	31527615
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	PDXDC1 REPS1 CCDC174 PABPC4 PSMD4 CTTNBP2NL PPP1R2 STRN COMMD8 PHF3 PABPC3 IK CAPRIN1 GOLGA4	7.16e-08	472	166	14	38943005
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PPRC1 ZSWIM5 SYNE1 ZSWIM6 FOCAD PLEKHH1 USP8 PHF3 BTBD7 RHOBTB2 LIMCH1 DYNC1H1 VPS13B	9.14e-08	407	166	13	12693553
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	UTP14A WDR55 PSMD4 CHD4 DDX55 CEP350 URB1 GTF3C2 ATXN10 PRKDC MTREX CAPRIN1 DYNC1H1 HERC5	9.49e-08	483	166	14	36912080
Pubmed	Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs.	PABPC4 PABPC1 PABPC3	1.07e-07	3	166	3	21940797
Pubmed	The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.	CCDC174 PABPC4 CHD3 CHD4 PABPC1 VPS33B ANKRD17 PRKDC CAPRIN1 DYNC1H1 GOLGA4	2.21e-07	298	166	11	30737378
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SERTAD2 SCRN1 DDX55 CTTNBP2NL FRMD4B DDX46 GTF3C2 CHD5 KDM2B ANKRD17 FAM149B1 MTREX LCOR GARRE1	2.86e-07	529	166	14	14621295
Pubmed	Human transcription factor protein interaction networks.	ARHGAP32 TCF3 CCDC174 KCMF1 PABPC4 UTP14A PSMD4 CHD3 TRRAP PABPC1 KIAA1671 GTF3C2 PABPC3 CHD5 SVIL SYNE2 KDM2B ANKRD17 ATXN10 CAPRIN1 GARRE1 DYNC1H1 PTCD3	3.56e-07	1429	166	23	35140242
Pubmed	PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family.	CDK17 CDK18 MAPK3	4.26e-07	4	166	3	1437147
Pubmed	Early thymocyte development is regulated by modulation of E2A protein activity.	RAG1 TCF3 PRKDC	4.26e-07	4	166	3	11560990
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	HSP90B1 REPS1 MAP1B ERCC6L UTP14A PSMD4 CHD3 CHD4 PABPC1 KIAA1671 USP8 DDX46 ANKRD17 PLCG1 PRKDC CKAP2 UTRN HERC5	5.95e-07	934	166	18	33916271
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	TFEB CDK17 ZSWIM8 TCF3 ERCC6L CCDC174 KCMF1 PABPC4 UTP14A WDR55 FYCO1 PABPC1 FRMD4B CEP350 BTBD7 PEX5 LIMCH1 MTREX IK	6.15e-07	1038	166	19	26673895
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	GBF1 REPS1 RBM45 PABPC4 TRPM2 WDR55 CHD3 CHD4 DDX55 CWC25 PABPC1 CEP350 DDX46 PHF3 SVIL ANKRD17 LIMCH1 ATXN10 MTREX CAPRIN1 DYNC1H1 PTCD3	6.90e-07	1371	166	22	36244648
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	HSP90B1 PABPC4 CHD3 CHD4 DDX55 TRRAP PABPC1 URB1 DDX46 GTF3C2 PHF3 ANKRD17 ATXN10 PRKDC MTREX IK CAPRIN1	7.17e-07	847	166	17	35850772
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	CDK17 NPR1 ERCC6L SYNE1 PPP1R12B PABPC4 PABPC1 CTTNBP2NL PPP1R2 CEP350 STRN URB1 DDX46 GTF3C2 SVIL PRKDC CAPRIN1 DYNC1H1 VPS13B PTCD3	7.23e-07	1155	166	20	20360068
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PHYKPL TCF3 KCNH8 MAP1B INPP5A TRPM2 CHD3 FRYL ZSWIM6 NXN TRRAP DENND2B KIAA1671 PLEKHH1 ANKRD17 LIMCH1 PLCG1 OLFM2 CKAP2 UTRN LCOR VPS13B GOLGA4	7.24e-07	1489	166	23	28611215
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	HSP90B1 SYNE1 PPP1R12B PABPC4 UTP14A CHD4 DDX55 PABPC1 DENND2B DDX46 CHD5 SVIL LIMCH1 PRKDC IK CAPRIN1 DYNC1H1 HERC5	7.48e-07	949	166	18	36574265
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	MAP1B PABPC4 UTP14A CHD3 CHD4 DDX55 TRRAP URB1 DDX46 GTF3C2 PHF3 PRKDC CKAP2 MTREX IK HERC5	8.19e-07	759	166	16	35915203
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	HSP90B1 MAP1B CHD4 TRRAP PABPC1 USP8 PABPC3 PLCG1 PRKDC CAPRIN1 DYNC1H1	9.11e-07	344	166	11	30333137
Pubmed	HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage.	PABPC4 PABPC1 PABPC3	1.06e-06	5	166	3	19956697
Pubmed	MKRN3-mediated ubiquitination of Poly(A)-binding proteins modulates the stability and translation of GNRH1 mRNA in mammalian puberty.	PABPC4 PABPC1 PABPC3	1.06e-06	5	166	3	33744966
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	HSP90B1 GBF1 SYNE1 PABPC4 UTP14A PSMD4 CHD4 DDX55 PABPC1 URB1 GTF3C2 VPS33B ATXN10 PLCG1 PRKDC MTREX IK DNAH5 CAPRIN1 DYNC1H1 GOLGA4 PTCD3	1.30e-06	1425	166	22	30948266
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CDK17 MAP9 ARHGAP32 HSP90B1 CTTNBP2 MAP1B SYNE1 PPP1R12B PABPC4 SCRN1 CHD3 PABPC1 STRN ATP8A1 PABPC3 SVIL LIMCH1 MAPK3 UTRN CAPRIN1 DYNC1H1 PTCD3	1.40e-06	1431	166	22	37142655
Pubmed	The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein.	PABPC4 PABPC1 PABPC3	2.11e-06	6	166	3	10358005
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	HSP90B1 MAP1B UTP14A PSMD4 CHD4 TRRAP PABPC1 URB1 FBXO22 GTF3C2 VPS33B ANKRD17 PLCG1 PRKDC MTREX IK UTRN CAPRIN1 DYNC1H1 GOLGA4 PTCD3	2.13e-06	1353	166	21	29467282
Pubmed	Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy.	MAP1B ATP8A1 PLCG1 MAPK3 DYNC1H1	2.18e-06	44	166	5	38351062
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	HSP90B1 REPS1 PPP1R12B KCMF1 PABPC4 UTP14A PSMD4 CHD4 PABPC1 PPP1R2 PHF3 SVIL KDM2B ANKRD17 LIMCH1 PRKDC MTREX IK CAPRIN1 DYNC1H1	2.33e-06	1247	166	20	27684187
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	ARHGAP32 HSP90B1 MAP1B PABPC4 E2F7 PSMD4 FRYL PABPC1 PRKDC MTREX IK CAPRIN1 PTCD3	2.73e-06	551	166	13	34728620
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	PDXDC1 HSP90B1 SYNE1 PEX3 UTP14A PSMD4 DDX55 KIAA1671 STRN MIGA2 GTF3C2 HIBCH VPS33B SYNE2 VPS13A PEX5 FUNDC2 ATXN10 CKAP2 CAPRIN1 VPS13B PTCD3	2.87e-06	1496	166	22	32877691
Pubmed	CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.	MAP1B KCMF1 PSMD4 CEP350 FBXO22 MTREX CAPRIN1 DYNC1H1	2.87e-06	182	166	8	31067453
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	CDK17 CDK18 HSP90B1 PABPC4 E2F7 PSMD4 CHD3 CHD4 PABPC1 DDX46 PABPC3 CHD5 PRKDC MAPK3 MTREX CAPRIN1 ATP4A DYNC1H1 PTCD3	2.88e-06	1153	166	19	29845934
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	PDXDC1 CDK17 GBF1 ERCC6L PABPC4 E2F7 PSMD4 FRYL NXN TRRAP PABPC1 PPP1R2 USP8 STRN NAA25 ATXN10 MTREX CAPRIN1 DYNC1H1 PTCD3	3.61e-06	1284	166	20	17353931
Pubmed	Chromosomal localization of three human poly(A)-binding protein genes and four related pseudogenes.	PABPC4 PABPC1 PABPC3	3.69e-06	7	166	3	10543404
Pubmed	NMD abnormalities during brain development in the Fmr1-knockout mouse model of fragile X syndrome.	MAP1B PABPC1 PABPC3	3.69e-06	7	166	3	34784943
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ARHGAP32 CTTNBP2 SYNE1 FYCO1 CHD4 PABPC1 STRN PABPC3 SVIL SYNE2 PEX5 ANKRD17 LIMCH1 MAPK3 CAPRIN1 DYNC1H1 GOLGA4	4.03e-06	963	166	17	28671696
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	CDK17 GBF1 FRYL PABPC1 USP8 SVIL PRKDC CKAP2 DYNC1H1	4.14e-06	255	166	9	15324660
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	HSP90B1 MAP1B UTP14A LAMB3 CHD3 TRRAP ATXN10 IK UTRN CAPRIN1 PTCD3	4.92e-06	410	166	11	26949251
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	HSP90B1 REPS1 MAP1B PABPC4 PSMD4 CHD4 KIAA1671 URB1 DDX46 COG1 COMMD8 SYNE2 IFI44L LIMCH1 PRKDC MTREX CAPRIN1 GARRE1 DYNC1H1 HERC5 PTCD3	5.59e-06	1440	166	21	30833792
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TFEB GBF1 REPS1 PPRC1 LAMB3 FYCO1 FRYL TRRAP SH2B2 FOCAD URB1 KLHL25 BTBD7 CHD5 PLCG1 PRKDC TTC38 DYNC1H1	6.25e-06	1105	166	18	35748872
Pubmed	BioID-based proteomic analysis of the Bid interactome identifies novel proteins involved in cell-cycle-dependent apoptotic priming.	CHD3 PABPC3 CHD5 LIMCH1 DYNC1H1	6.69e-06	55	166	5	33067418
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	HSP90B1 PABPC4 UTP14A PABPC1 SVIL MTREX IK CAPRIN1 PTCD3	7.39e-06	274	166	9	34244482
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	HSP90B1 PABPC4 UTP14A LAMB3 DDX55 PABPC1 KIAA1671 PHF3 CHD5 SVIL ANKRD17 PRKDC CKAP2 MTREX IK CAPRIN1 ATP4A DYNC1H1 PTCD3	9.82e-06	1257	166	19	36526897
Pubmed	Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.	HSP90B1 MAP1B UTP14A CHD3 CHD4 DDX46 PRKDC	1.07e-05	156	166	7	37108203
Pubmed	Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts.	PABPC4 PABPC1 MTREX	1.25e-05	10	166	3	27871484
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ARHGAP32 ERCC6L PRICKLE1 STK31 TRDN CEP350 PLEKHH1 USP8 SYNE2 VPS13A KDM2B ANKRD17 IRAK3	1.31e-05	638	166	13	31182584
Pubmed	Defining the membrane proteome of NK cells.	HGF HSP90B1 GBF1 ERCC6L PEX3 FYCO1 CHD4 DDX55 PABPC1 CEP350 ATP8A1 CHD5 ANKRD17 ATXN10 PRKDC CAPRIN1 FMNL1 DYNC1H1	1.32e-05	1168	166	18	19946888
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	GBF1 SYNE1 SCRN1 URB1 PHF3 RHOBTB2 CHD5 SYNE2	1.36e-05	225	166	8	12168954
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	MAP1B UTP14A CHD4 DDX55 CEP350 GTF3C2 ANKRD17 LIMCH1 PRKDC IK HERC5 PTCD3	1.38e-05	547	166	12	37267103
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	REPS1 MAP1B ERCC6L TRRAP KIAA1671 DDX46 GTF3C2 PHF3 KDM2B PRKDC IK DYNC1H1	1.43e-05	549	166	12	38280479
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	PDXDC1 HSP90B1 MAP1B PABPC4 LAMB3 PSMD4 PABPC1 PABPC3 LIMCH1 ATXN10 PRKDC DYNC1H1 PTCD3	1.52e-05	647	166	13	26618866
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	GBF1 MAP1B ERCC6L UTP14A PABPC1 AEBP2 GARRE1 DYNC1H1	1.70e-05	232	166	8	25515538
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	MAP9 TCF3 PPP1R12B PEX3 PABPC4 FYCO1 PABPC1 CEP350 URB1 COMMD8 FUNDC2 LIMCH1 MAPK3 MTREX	1.71e-05	754	166	14	33060197
Pubmed	ERRgamma regulates cardiac, gastric, and renal potassium homeostasis.	KLK6 KLK1 ATP4A	1.71e-05	11	166	3	19965931
Pubmed	Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.	MAP9 MAP1B PPP1R12B SVIL LIMCH1	1.77e-05	67	166	5	29254152
Pubmed	Molecular analysis of a major antigenic region of the 240-kD protein of Mi-2 autoantigen.	CHD3 CHD4	2.26e-05	2	166	2	7560064
Pubmed	Cardiac apoptosis in severe relapsing fever borreliosis.	RAG1 PRKDC	2.26e-05	2	166	2	16239571
Pubmed	Recombinase-activating gene 1-associated expression of the myelin basic protein 1-11-specific transgenic T-cell receptor in H-2b mice.	RAG1 PRKDC	2.26e-05	2	166	2	18752298
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	2.26e-05	2	166	2	11792814
Pubmed	During the early prediabetic period in NOD mice, the pathogenic CD8(+) T-cell population comprises multiple antigenic specificities.	RAG1 PRKDC	2.26e-05	2	166	2	12498815
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	2.26e-05	2	166	2	24931616
Pubmed	The major dermatomyositis-specific Mi-2 autoantigen is a presumed helicase involved in transcriptional activation.	CHD3 CHD4	2.26e-05	2	166	2	7575689
Pubmed	The promoter of the Poly(A) binding protein 2 (Pabp2) retroposon is derived from the 5'-untranslated region of the Pabp1 progenitor gene.	PABPC1 PABPC3	2.26e-05	2	166	2	10534404
Pubmed	TRPM2 Is Not Required for T-Cell Activation and Differentiation.	RAG1 TRPM2	2.26e-05	2	166	2	35095852
Pubmed	Novel antibody reagents for characterization of drug- and tumor microenvironment-induced changes in epithelial-mesenchymal transition and cancer stem cells.	HGF PRKDC	2.26e-05	2	166	2	29928062
Pubmed	Substrate specificity of human kallikreins 1 and 6 determined by phage display.	KLK6 KLK1	2.26e-05	2	166	2	18359858
Pubmed	Nucleotide sequence of a mouse testis poly(A) binding protein cDNA.	PABPC1 PABPC3	2.26e-05	2	166	2	1630930
Pubmed	An intrinsic BM hematopoietic niche occupancy defect of HSC in scid mice facilitates exogenous HSC engraftment.	RAG1 PRKDC	2.26e-05	2	166	2	22147896
Pubmed	Myotendinous junction defects and reduced force transmission in mice that lack alpha7 integrin and utrophin.	ITGA7 UTRN	2.26e-05	2	166	2	19729483
Pubmed	Developmental expression of poly(A) binding protein mRNAs during spermatogenesis in the mouse.	PABPC1 PABPC3	2.26e-05	2	166	2	7893484
Pubmed	DNA-dependent protein kinase promotes DNA end processing by MRN and CtIP.	RBBP8 PRKDC	2.26e-05	2	166	2	31934630
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	2.26e-05	2	166	2	22768332
Pubmed	Characterization of two cytoplasmic poly(A)-binding proteins, PABPC1 and PABPC2, in mouse spermatogenic cells.	PABPC1 PABPC3	2.26e-05	2	166	2	19020299
Pubmed	Potential role of PCTAIRE-2, PCTAIRE-3 and P-Histone H4 in amyloid precursor protein-dependent Alzheimer pathology.	CDK17 CDK18	2.26e-05	2	166	2	26885753
Pubmed	Development of functional B cells in a line of SCID mice with transgenes coding for anti-double-stranded DNA antibody.	RAG1 PRKDC	2.26e-05	2	166	2	16393973
Pubmed	Functional compensation for the loss of testis-specific poly(A)-binding protein, PABPC2, during mouse spermatogenesis.	PABPC1 PABPC3	2.26e-05	2	166	2	26971890
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	2.26e-05	2	166	2	17267447
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	2.26e-05	2	166	2	24718612
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	2.26e-05	2	166	2	24586179
Pubmed	Levels of free PABP are limited by newly polyadenylated mRNA in early Spisula embryogenesis.	PABPC1 PABPC3	2.26e-05	2	166	2	10954604
Pubmed	Novel γ-sarcoglycan interactors in murine muscle membranes.	SGCG SVIL	2.26e-05	2	166	2	35065666
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	2.26e-05	2	166	2	17761684
Pubmed	The mouse gene encoding the testis-specific isoform of Poly(A) binding protein (Pabp2) is an expressed retroposon: intimations that gene expression in spermatogenic cells facilitates the creation of new genes.	PABPC1 PABPC3	2.26e-05	2	166	2	9732454
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	2.26e-05	2	166	2	31578382
Pubmed	Novel role of the Ras cascade in memory B cell response.	RAG1 PRKDC	2.26e-05	2	166	2	16111632
Pubmed	The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte.	RAG1 MAPK3	2.26e-05	2	166	2	8706129
Pubmed	PRICKLE1 × FOCAD Interaction Revealed by Genome-Wide vQTL Analysis of Human Facial Traits.	PRICKLE1 FOCAD	2.26e-05	2	166	2	34434215
Pubmed	The catalytic subunit of DNA-protein kinase (DNA-PKcs) is not required for Ig class-switch recombination.	RAG1 PRKDC	2.26e-05	2	166	2	17296939
Pubmed	Reduced switching in SCID B cells is associated with altered somatic mutation of recombined S regions.	RAG1 PRKDC	2.26e-05	2	166	2	14662857
Pubmed	Expression of a bcl-2 transgene reduces proliferation and slows turnover of developing B lymphocytes in vivo.	RAG1 PRKDC	2.26e-05	2	166	2	9278319
Pubmed	Effect of different Ig transgenes on B cell differentiation in scid mice.	RAG1 PRKDC	2.26e-05	2	166	2	9088976
Interaction	ATOH1 interactions	TCF3 MAP1B TRRAP CEP350 PRKDC MAPK3 UTRN DYNC1H1	2.60e-07	80	162	8	int:ATOH1
Interaction	GOLGA1 interactions	PDXDC1 GBF1 ERCC6L CEP350 KIAA1671 STRN FBXO22 COG1 PEX5 ATXN10 GOLGA4	2.79e-07	183	162	11	int:GOLGA1
Interaction	SIRT7 interactions	ZSWIM8 MAP1B PABPC4 UTP14A FRYL CHD4 TRRAP PABPC1 URB1 DDX46 PHF3 SYNE2 ANKRD17 PRKDC MTREX IK UTRN CAPRIN1 DYNC1H1 HERC5 PTCD3	5.83e-07	744	162	21	int:SIRT7
Interaction	YWHAG interactions	TFEB CDK17 CDK18 HGF ARHGAP32 GBF1 ERCC6L PABPC4 FRYL TRRAP PABPC1 DENND2B CEP350 KIAA1671 USP8 MTMR4 PHF3 SVIL SYNE2 ANKRD17 PRKDC CKAP2 MAPK3 MTREX UTRN GARRE1 EDRF1 DYNC1H1	7.15e-07	1248	162	28	int:YWHAG
Interaction	SFN interactions	ARHGAP32 HSP90B1 TCF3 GBF1 MAP1B ERCC6L FRYL PABPC1 DENND2B PPP1R2 CEP350 KIAA1671 USP8 MTMR4 PHF3 SVIL ANKRD17 MTREX GARRE1	3.14e-06	692	162	19	int:SFN
Interaction	HSP90AB1 interactions	CDK18 HSP90B1 GBF1 MAP1B RBM45 RBBP8 PSMD4 CHD3 TRDN CTTNBP2NL KIAA1671 USP8 DDX46 RHOBTB2 MYO3B SVIL VPS13A PLCG1 PRKDC MAPK3 MAPK13 EDRF1	9.20e-06	960	162	22	int:HSP90AB1
Interaction	MB interactions	CCDC174 PSMD4 CHD3 CHD4	1.42e-05	19	162	4	int:MB
Interaction	PIP interactions	TCF3 REPS1 RBBP8 CHD3 CHD4 CTTNBP2NL CEP350 VPS33B AEBP2	1.62e-05	181	162	9	int:PIP
Interaction	LUC7L2 interactions	PABPC4 CHD3 CHD4 PABPC1 NAA25 DDX46 FBXO22 PABPC3 SVIL IK DYNC1H1 PTCD3	2.96e-05	353	162	12	int:LUC7L2
Interaction	NPM1 interactions	TCF3 RBM44 MAP1B RBM45 PABPC4 UTP14A WDR55 PSMD4 CHD3 CHD4 DDX55 TRRAP TRDN PABPC1 ADGB URB1 SYNE2 LIMCH1 PLCG1 PRKDC UTRN FMNL1 HERC5 PTCD3	3.33e-05	1201	162	24	int:NPM1
Interaction	DNAJC7 interactions	PABPC4 TRRAP FBXO22 GTF3C2 SVIL VPS13A FUNDC2 ATXN10 PRKDC LCOR EDRF1 VPS13B HERC5	4.11e-05	425	162	13	int:DNAJC7
Interaction	PAPOLB interactions	TCF3 PABPC1 TTC38	5.87e-05	10	162	3	int:PAPOLB
Interaction	ADGB interactions	TRRAP ADGB IK	5.87e-05	10	162	3	int:ADGB
Interaction	CTNNB1 interactions	ARHGAP32 HSP90B1 TCF3 PPP1R12B PABPC4 UTP14A PSMD4 CHD4 TRRAP PABPC1 KIAA1671 USP8 GLIS2 SVIL SYNE2 LIMCH1 PRKDC UTRN CAPRIN1 DYNC1H1 HERC5	6.11e-05	1009	162	21	int:CTNNB1
Interaction	PPP2CB interactions	CDK17 CDK18 CTTNBP2 SERTAD2 CTTNBP2NL CEP350 STRN IK GOLGA4 HERC5	6.23e-05	267	162	10	int:PPP2CB
Interaction	IFI16 interactions	HSP90B1 MAP1B SYNE1 PABPC4 UTP14A E2F7 CHD4 DDX55 PABPC1 URB1 GTF3C2 SVIL ATXN10 MAPK3 MTREX CAPRIN1 HERC5	6.46e-05	714	162	17	int:IFI16
Interaction	YWHAB interactions	TFEB CDK17 CDK18 ARHGAP32 GBF1 PABPC4 FRYL TRRAP DENND2B CEP350 KIAA1671 USP8 SLC8A3 MTMR4 VPS33B PHF3 SVIL ANKRD17 MTREX GARRE1 DYNC1H1	6.55e-05	1014	162	21	int:YWHAB
Interaction	ITGB3 interactions	HSP90B1 MAP1B TRRAP USP8 PRKDC MAPK3 CAPRIN1 DYNC1H1	7.13e-05	170	162	8	int:ITGB3
Interaction	YWHAH interactions	TFEB CDK17 CDK18 ARHGAP32 GBF1 ERCC6L FRYL DENND2B CEP350 KIAA1671 USP8 MTMR4 PHF3 SVIL SYNE2 ANKRD17 LIMCH1 MTREX UTRN GARRE1 EDRF1 GOLGA4	7.43e-05	1102	162	22	int:YWHAH
Interaction	PSMD3 interactions	MAP1B ZFAND2B PEX3 KCMF1 PSMD4 CCDC92 TRRAP PABPC1 STRN VPS33B DYNC1H1 GOLGA4	7.73e-05	390	162	12	int:PSMD3
Interaction	JPH3 interactions	CACNA1D MAP9 CWC25 DDX46 SVIL	7.93e-05	55	162	5	int:JPH3
Interaction	MEX3B interactions	PABPC4 NXN PABPC1 KIAA1671 ANKRD17 CAPRIN1 GARRE1 EDRF1 PTCD3	7.99e-05	222	162	9	int:MEX3B
Interaction	CIT interactions	RAG1 ARHGAP32 HSP90B1 SYNE1 PABPC4 UTP14A PCDHA6 CHD3 CHD4 TRRAP PABPC1 KIAA1671 URB1 MTMR4 DDX46 FBXO22 GTF3C2 PABPC3 SVIL SYNE2 PRKDC MTREX IK CAPRIN1 DYNC1H1 GOLGA4	9.31e-05	1450	162	26	int:CIT
Interaction	PPIA interactions	PDXDC1 CACNA1D REPS1 MAP1B CCDC174 PABPC4 PSMD4 TRRAP CTTNBP2NL PPP1R2 STRN DDX46 COMMD8 PHF3 PABPC3 RHOBTB2 IK CAPRIN1 GOLGA4	9.80e-05	888	162	19	int:PPIA
Interaction	EZH1 interactions	MAP9 CWC25 DDX46 AEBP2 IK LCOR	9.91e-05	92	162	6	int:EZH1
Interaction	USP36 interactions	UTP14A WDR55 PSMD4 CHD3 CHD4 DDX55 CEP350 URB1 GTF3C2 ATXN10 PRKDC MTREX CAPRIN1 DYNC1H1 HERC5	1.02e-04	599	162	15	int:USP36
Interaction	TAL1 interactions	TCF3 CHD3 CHD4 TRRAP MAPK3 DYNC1H1	1.05e-04	93	162	6	int:TAL1
Interaction	IVNS1ABP interactions	HSP90B1 TCF3 GBF1 PRICKLE1 PABPC4 CHD3 TRRAP SYNE2	1.06e-04	180	162	8	int:IVNS1ABP
Interaction	DNAH10 interactions	HSP90B1 DDX46 CHD5 DNAH5	1.07e-04	31	162	4	int:DNAH10
Interaction	PRC1 interactions	HSP90B1 GBF1 ATP8A2 SYNE1 PABPC4 CHD4 TRRAP PABPC1 KIAA1671 URB1 DDX46 PABPC3 CHD5 TM7SF2 ATXN10 PRKDC CKAP2 IK CAPRIN1 DYNC1H1	1.10e-04	973	162	20	int:PRC1
Interaction	STK38 interactions	TCF3 GBF1 MAP1B TRRAP RHOBTB2 PRKDC DYNC1H1 HERC5	1.15e-04	182	162	8	int:STK38
Interaction	HSF1 interactions	HSP90B1 REPS1 PABPC4 CHD3 CHD4 TRRAP PABPC1 GTF3C2 HIBCH COG1 SYNE2 KDM2B LIMCH1 PRKDC MAPK3	1.22e-04	609	162	15	int:HSF1
Interaction	USP7 interactions	ANKRD31 TCF3 ERCC6L RBM45 MYO7B SYNE1 TOGARAM2 PSMD4 STK31 TRRAP PABPC1 PPP1R2 KLHL5 FBXO22 STXBP6 SVIL FUNDC2 IRAK3 MTREX DNAH5 UTRN LCOR DYNC1H1 VPS13B	1.34e-04	1313	162	24	int:USP7
Interaction	DDX23 interactions	MAP1B SYNE1 UTP14A CHD3 CHD4 DDX55 CWC25 TRRAP URB1 DDX46 FBXO22 PHF3 IK	1.40e-04	480	162	13	int:DDX23
Interaction	PRMT1 interactions	ARHGAP32 HSP90B1 GBF1 MAP1B RBM45 PABPC4 E2F7 SCRN1 PSMD4 FRYL PABPC1 NFATC2IP PRKDC MTREX IK IGSF21 CAPRIN1 GOLGA4 PTCD3	1.76e-04	929	162	19	int:PRMT1
Interaction	PAN3 interactions	PABPC4 PABPC1 PABPC3 SVIL GARRE1	1.77e-04	65	162	5	int:PAN3
Interaction	SQSTM1 interactions	ARHGAP32 GBF1 MAP1B ERCC6L RBM45 PABPC4 PSMD4 FRYL PABPC1 CEP350 KIAA1671 USP8 MTMR4 SERPINE2 COMMD8 PEX5 ATXN10 MAPK3 IK MAPK13 UTRN EDRF1 DYNC1H1	1.84e-04	1257	162	23	int:SQSTM1
Interaction	STRIP2 interactions	CTTNBP2 PRICKLE1 CTTNBP2NL STRN SYNE2	2.19e-04	68	162	5	int:STRIP2
Interaction	SGK3 interactions	MAP1B CHD3 CHD4 DYNC1H1 PTCD3	2.34e-04	69	162	5	int:SGK3
Interaction	U2AF2 interactions	HSP90B1 MAP1B ARHGAP36 PABPC4 LAMB3 CHD3 CHD4 PABPC1 DDX46 GLIS2 PRKDC IK CAPRIN1 DYNC1H1 GOLGA4	2.52e-04	651	162	15	int:U2AF2
Interaction	SMG7 interactions	ZSWIM8 PABPC1 MTMR4 VPS33B CHD5 KDM2B ANKRD17 CAPRIN1 GARRE1 PTCD3	2.66e-04	319	162	10	int:SMG7
Interaction	POU5F1 interactions	TFEB KCMF1 CHD3 CHD4 TRRAP GTF3C2 PHF3 CHD5 KDM2B ANKRD17 ATXN10 PRKDC DYNC1H1 PTCD3	2.73e-04	584	162	14	int:POU5F1
Interaction	DOT1L interactions	HSP90B1 RBM45 PABPC4 CHD3 CHD4 DDX55 TRRAP PABPC1 URB1 DDX46 GTF3C2 PHF3 ATXN10 PRKDC MTREX IK CAPRIN1	2.79e-04	807	162	17	int:DOT1L
Interaction	BMI1 interactions	SYNE1 PABPC4 CHD3 CHD4 RYR3 PHF3 PABPC3 KDM2B PLCG1 PRKDC MTREX IK CAPRIN1 DYNC1H1 PTCD3	2.87e-04	659	162	15	int:BMI1
Interaction	TOP3B interactions	TFEB HSP90B1 GBF1 REPS1 PPRC1 KCMF1 LAMB3 FYCO1 FRYL TRRAP PABPC1 SH2B2 FOCAD URB1 FBXO22 KLHL25 BTBD7 CHD5 SVIL ANKRD17 PLCG1 PRKDC CAPRIN1 TTC38 DYNC1H1	2.91e-04	1470	162	25	int:TOP3B
Cytoband	Ensembl 112 genes in cytogenetic band chr6q24	REPS1 PEX3 ADGB UTRN	1.95e-04	78	167	4	chr6q24
GeneFamily	Zinc fingers SWIM-type\|Mitogen-activated protein kinase kinase kinases	ZSWIM8 ZSWIM5 ZSWIM6	1.84e-05	9	111	3	90
GeneFamily	PHD finger proteins\|NuRD complex	CHD3 CHD4 CHD5	4.76e-05	12	111	3	1305
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE2	2.22e-04	4	111	2	1252
GeneFamily	PHD finger proteins	CHD3 CHD4 PHF3 CHD5 KDM2B	2.31e-04	90	111	5	88
GeneFamily	Protein phosphatase catalytic subunits\|STRIPAK complex	CTTNBP2 CTTNBP2NL STRN	2.38e-04	20	111	3	1371
GeneFamily	RNA binding motif containing	RBM44 RBM45 PPRC1 PABPC4 PABPC1 PABPC3	2.02e-03	213	111	6	725
GeneFamily	Mitogen-activated protein kinases	MAPK3 MAPK13	2.79e-03	13	111	2	651
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	MYO7B FRMD4B PLEKHH1	3.58e-03	50	111	3	1293
GeneFamily	ATPase phospholipid transporting	ATP8A2 ATP8A1	3.72e-03	15	111	2	1210
GeneFamily	Kallikreins	KLK6 KLK1	4.24e-03	16	111	2	616
GeneFamily	AAA ATPases\|Peroxins	PEX3 PEX5	4.24e-03	16	111	2	957
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	KCMF1 UTRN	5.36e-03	18	111	2	91
Coexpression	PARENT_MTOR_SIGNALING_UP	CDK18 GBF1 GALT SYNE1 TRPM2 LAMB3 CHD4 ITGA7 DENND2B CEP350 PHF3 SVIL SYNE2 PEX5 PLCG1 TTC38	7.66e-07	567	167	16	M16909
Coexpression	GSE16385_IL4_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP	CACNA1D ARHGAP32 INPP5A MATK FRMD4B BTBD7 PRKDC MTREX VPS13B	4.53e-06	194	167	9	M8017
Coexpression	GSE27896_HDAC6_KO_VS_WT_TREG_UP	PPRC1 STRN COG1 KDM2B PLCG1 UTRN GARRE1 GOLGA4	1.80e-05	176	167	8	M8248
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	PPRC1 SERTAD2 FRYL CEP350 STRN PHF3 VPS13A IFI44L EDRF1 VPS13B	2.41e-05	300	167	10	M8702
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	TFEB MAP1B PRICKLE1 SYNE1 PPP1R12B FYCO1 CHD3 CHD4 ITGA7 FRMD4B FOCAD KLHL5 STRN MTMR4 ATP8A1 MIGA2 GLIS2 SVIL PEX5 GOLGA4	2.55e-05	1102	167	20	M2369
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	TFEB MAP1B PRICKLE1 SYNE1 PPP1R12B FYCO1 CHD3 CHD4 ITGA7 FRMD4B FOCAD KLHL5 STRN MTMR4 ATP8A1 MIGA2 GLIS2 SVIL PEX5 GOLGA4	3.37e-05	1124	167	20	MM1070
Coexpression	MITSIADES_RESPONSE_TO_APLIDIN_DN	ERCC6L CHD4 TRRAP MTMR4 DDX46 ATP8A1 NFATC2IP PRKDC CKAP2	3.42e-05	250	167	9	M11318
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	CDK17 GBF1 MAP1B PEX3 FRYL TRRAP DENND2B CEP350 GTF3C2 PHF3 SYNE2 VPS13A ANKRD17 MTREX GARRE1 VPS13B GOLGA4	3.55e-05	856	167	17	M4500
Coexpression	BILD_SRC_ONCOGENIC_SIGNATURE	RAG1 PRICKLE1 TRRAP FRMD4B VPS13B	3.75e-05	59	167	5	M116
Coexpression	GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP	ZSWIM8 ARHGAP32 SCRN1 FOCAD IFI44L ATXN10 CKAP2 CAPRIN1	4.33e-05	199	167	8	M3474
Coexpression	GSE6875_TCONV_VS_FOXP3_KO_TREG_DN	HSP90B1 SYNE1 PEX3 ATP8A1 PLCG1 PRKDC UTRN PTCD3	4.49e-05	200	167	8	M6802
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	CDK17 MAP1B PEX3 FRYL TRRAP CEP350 PHF3 VPS13A ANKRD17 LIMCH1 MTREX GOLGA4	4.73e-05	466	167	12	M13522
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	PHYKPL REPS1 MAP1B CHD4 FRMD4B PLEKHH1 KLHL5 STXBP6 COG1 COMMD8 SYNE2 AEBP2 CKAP2 EDRF1 DYNC1H1 GOLGA4	1.25e-05	595	161	16	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	MAP9 FRYL CEP350 USP8 STRN PRKDC UTRN CAPRIN1 DYNC1H1 VPS13B	3.29e-09	193	167	10	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 MCF2L2 FRYL NFATC2IP SYNE2 VPS13A IFI44L PLCG1 UTRN VPS13B	3.29e-09	193	167	10	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CDK17 SYNE1 FRYL PHF3 SYNE2 VPS13A IFI44L UTRN VPS13B GOLGA4	4.42e-09	199	167	10	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	MAP1B PPP1R12B SCRN1 CEP350 KLHL5 PHF3 SYNE2 LIMCH1 UTRN GOLGA4	4.42e-09	199	167	10	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	Macroglial-Oligodendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CDK18 KLK6 KCNH8 FRYL FRMD4B GREB1L PLEKHH1 ATP8A1 LIMCH1	6.91e-08	200	167	9	4dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCell	Macroglial-Oligodendrocytes-OPALIN--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CDK18 KLK6 KCNH8 FRYL FRMD4B GREB1L PLEKHH1 ATP8A1 LIMCH1	6.91e-08	200	167	9	26b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FRYL CEP350 PHF3 SYNE2 IFI44L UTRN DYNC1H1 GOLGA4 HERC5	6.91e-08	200	167	9	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Macroglial-Oligodendrocytes-OPALIN---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CDK18 KLK6 KCNH8 FRYL FRMD4B GREB1L PLEKHH1 ATP8A1 LIMCH1	6.91e-08	200	167	9	1314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCell	Macroglial-Oligodendrocytes-OPALIN-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CDK18 KLK6 KCNH8 FRYL FRMD4B GREB1L PLEKHH1 ATP8A1 LIMCH1	6.91e-08	200	167	9	8b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	HSP90B1 CHD4 PHF3 SYNE2 IFI44L UTRN DYNC1H1 GOLGA4 HERC5	6.91e-08	200	167	9	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Macroglial-Oligodendrocytes-OPALIN----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CDK18 KLK6 KCNH8 FRYL FRMD4B GREB1L PLEKHH1 ATP8A1 LIMCH1	6.91e-08	200	167	9	272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCell	Macroglial-Oligodendrocytes-OPALIN\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CDK18 KLK6 KCNH8 FRYL FRMD4B GREB1L PLEKHH1 ATP8A1 LIMCH1	6.91e-08	200	167	9	5f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 MCF2L2 CHD3 FRYL SYNE2 VPS13A UTRN GOLGA4	8.18e-07	197	167	8	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	BAL-Severe-cDC_10\|Severe / Compartment, Disease Groups and Clusters	SERTAD2 CHD3 CEP350 NAA25 MTMR4 ATP8A1 KDM2B LIMCH1	8.83e-07	199	167	8	54bdadd04abaf8caa948b0177c037bc089ca07e6
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	SCRN1 CEP350 KLHL5 DDX46 PHF3 SYNE2 DNAH5 GOLGA4	8.83e-07	199	167	8	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / Treatment groups by lineage, cell group, cell type	CTTNBP2 MAP1B PI16 TRDN FRMD4B SERPINE2 SYNE2 GARRE1	9.17e-07	200	167	8	b17eb1587ca86c3d40515128a00a8d8fd787fccf
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	SYNE1 TOGARAM2 ATP8A1 SYNE2 IFI44L PLCG1 GOLGA4	2.09e-06	156	167	7	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	Control-Myeloid-MoAM1,_IL1R2\|Myeloid / Condition, Lineage and Cell class	HGF PRICKLE1 SYNE1 TRPM2 IFI44L IGSF21 HERC5	3.29e-06	167	167	7	6e5140527437193f441ca96893b9a00d346614f3
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-skeletal_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGCG LRTM1 TOGARAM2 TRDN LRRC14B SLC8A3 CLCN1	4.31e-06	174	167	7	4a6e04b4f12b87c15fa1409989cbe32c43736369
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TFEB CDK18 KLK6 KCNH8 PI16 FRMD4B PLEKHH1	5.59e-06	181	167	7	a8e9ea73c24109a5d4d28bc0577cc869ad932a4d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TFEB CDK18 KLK6 KCNH8 PI16 FRMD4B PLEKHH1	6.01e-06	183	167	7	93213124e55d1b673dd345188caf8b5bd31d99fe
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TFEB CDK18 KLK6 KCNH8 PI16 FRMD4B PLEKHH1	6.92e-06	187	167	7	f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	CDK17 FRYL CTTNBP2NL KIAA1671 ATP8A1 SYNE2 UTRN	6.92e-06	187	167	7	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TFEB CDK18 KLK6 KCNH8 PI16 FRMD4B PLEKHH1	7.17e-06	188	167	7	14072d0b82df55711d5356b2209f4f0bdd90dc27
ToppCell	Epithelial-Epithelial-D_(Ciliated)\|Epithelial / shred on cell class and cell subclass (v4)	MAP9 MAP1B SYNE1 TOGARAM2 ADGB CFAP206 DNAH5	7.17e-06	188	167	7	8f30535a32968a81a304315a49c0d90a77d36948
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TFEB CDK18 KLK6 KCNH8 PI16 FRMD4B PLEKHH1	7.42e-06	189	167	7	70eea8c94fa56bb15bee8065de47acea156794e9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CDK17 PI16 NXN RYR3 KIAA1671 SERPINE2 UTRN	7.95e-06	191	167	7	b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 KCNH8 LAMB3 GREB1L ATP8A1 MYO3B DNAH5	7.95e-06	191	167	7	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 RBBP8 SYNE1 STRN SVIL SYNE2 DNAH5	8.80e-06	194	167	7	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 KCNH8 LAMB3 GREB1L ATP8A1 MYO3B DNAH5	8.80e-06	194	167	7	6b286992d4bb56013c0ea5a7601d3476d806175a
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 KCNH8 LAMB3 GREB1L ATP8A1 MYO3B DNAH5	8.80e-06	194	167	7	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CDK17 NXN CTTNBP2NL FRMD4B SERPINE2 LIMCH1 GARRE1	9.09e-06	195	167	7	d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D MAP1B FRYL CHD4 VPS13A DYNC1H1 GOLGA4	9.09e-06	195	167	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	COVID-19-Heart-EC_1\|Heart / Disease (COVID-19 only), tissue and cell type	CDK17 SYNE1 FRYL KLHL5 SYNE2 IFI44L UTRN	9.09e-06	195	167	7	50a193475db1bb1e05b8590225a553688c372c14
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D MAP1B FRYL CHD4 VPS13A DYNC1H1 GOLGA4	9.09e-06	195	167	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-PFC\|World / Primary Cells by Cluster	CTTNBP2 ATP8A2 FRMD4B SERPINE2 SYNE2 LIMCH1 DYNC1H1	9.72e-06	197	167	7	2c3b0072f8e1e09c77a85c6fc3133d1796932fb2
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-PFC-29\|World / Primary Cells by Cluster	CTTNBP2 ATP8A2 FRMD4B SERPINE2 SYNE2 LIMCH1 DYNC1H1	9.72e-06	197	167	7	c5bc0e7eb85642b270efc2ba92b13a736af22052
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	SYNE1 LAMB3 SYNE2 IFI44L PLCG1 UTRN TTC38	1.00e-05	198	167	7	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDK18 KLK6 MAP1B PI16 PLEKHH1 STXBP6 LIMCH1	1.04e-05	199	167	7	5d2e85e40b6b52b1809e680b952913d77215b3d0
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDK18 KLK6 MAP1B PI16 PLEKHH1 STXBP6 LIMCH1	1.04e-05	199	167	7	9dd4b17fb8c70ab9e126b23b72600463f3db832d
ToppCell	mild-MAIT\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 PHF3 SYNE2 AEBP2 IFI44L UTRN GOLGA4	1.04e-05	199	167	7	cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 PPP1R12B ZSWIM6 FOCAD LIMCH1 UTRN VPS13B	1.04e-05	199	167	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDK18 KLK6 MAP1B PI16 PLEKHH1 STXBP6 LIMCH1	1.04e-05	199	167	7	6fb5f931e6217142de38c1fffc011e63bda4772b
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDK18 KLK6 MAP1B PI16 PLEKHH1 STXBP6 LIMCH1	1.04e-05	199	167	7	1bb5797e8e0552bf9b44bf4c958d1aa6dbe6c756
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD8+_T_activated\|COVID-19_Severe / Disease, condition lineage and cell class	MATK SYNE1 KIAA1671 SYNE2 IFI44L UTRN TTC38	1.07e-05	200	167	7	b7f80b2db07119069fbf3d245cf1ad79e8648bab
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Artery\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CTTNBP2 PI16 TRDN FRMD4B SERPINE2 SYNE2 GARRE1	1.07e-05	200	167	7	77ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCell	Control_saline-Endothelial-Endothelial-Artery\|Control_saline / Treatment groups by lineage, cell group, cell type	CTTNBP2 MAP1B PI16 TRDN SERPINE2 SYNE2 GARRE1	1.07e-05	200	167	7	65b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Artery\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CTTNBP2 MAP1B PI16 TRDN FRMD4B SERPINE2 GARRE1	1.07e-05	200	167	7	ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	SYNE1 KIAA1671 SYNE2 IFI44L PLCG1 UTRN TTC38	1.07e-05	200	167	7	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Artery\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CTTNBP2 PI16 TRDN FRMD4B SERPINE2 SYNE2 GARRE1	1.07e-05	200	167	7	b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1D HGF MAP1B PRICKLE1 SYNE1 SERPINE2 MYO3B	1.07e-05	200	167	7	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT2_Precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	KCNH8 LAMB3 ATP8A1 MAPK13 DNAH5 ATP4A	2.64e-05	155	167	6	9cad73d0b8ead289e1073d1a2e00bbeb1228308c
ToppCell	Control-Myeloid-MoAM1,_IL1R2\|Control / Condition, Lineage and Cell class	HGF PRICKLE1 TRPM2 IFI44L IGSF21 HERC5	4.02e-05	167	167	6	ab6029ba037b6a499da8758864c44e174cde5587
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 SYNE1 TRPM2 SVIL MAPK3 MAPK13	4.29e-05	169	167	6	2341eddfedaad8cee779c37bb87f7def058588ca
ToppCell	facs-Marrow-Granulocytes-18m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 SYNE1 TRPM2 SVIL MAPK3 MAPK13	4.29e-05	169	167	6	94871936ccfc73b56d425373b989b87c059d4493
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 ABCA13 SYNE1 TRPM2 SVIL MAPK13	4.58e-05	171	167	6	ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCell	facs-Marrow-Granulocytes\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 ABCA13 SYNE1 SVIL MAPK3 MAPK13	4.58e-05	171	167	6	1701dedf0c18751db6c9fee3d93fff150ed0e17f
ToppCell	NS-critical-d_0-4-Lymphoid-B_cell\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GALT SCRN1 URB1 RHOBTB2 FAM149B1 LCOR	4.58e-05	171	167	6	bd1ebd9037a740ad8c01c460d778b0973d8b56df
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 ABCA13 SYNE1 TRPM2 SVIL MAPK13	4.58e-05	171	167	6	97ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 ABCA13 SYNE1 NXN SERPINE2 MAPK13	5.55e-05	177	167	6	b41e975e8368e2618b015be095efe8c0e001c78b
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI16 ABCA13 SYNE1 NXN SERPINE2 MAPK13	5.55e-05	177	167	6	15d1de38e4f1a0d4a786d83ee92240f44bdff006
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERCC6L ABCA13 FOXN4 E2F7 CEP350 LRRC14B	5.91e-05	179	167	6	d15182c668d7c37be8214cad9f1fe35d1409c9a1
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERCC6L ABCA13 FOXN4 E2F7 CEP350 LRRC14B	5.91e-05	179	167	6	e22a275a7c0ed19113c833a75d6c49fcc19aa13a
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	CFAP47 ABCA13 TOGARAM2 ADGB CFAP206 DNAH5	6.48e-05	182	167	6	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	MYO7B ABCA13 FRMD4B SERPINE2 SYNE2 VPS13A	6.88e-05	184	167	6	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TFEB CDK18 KLK6 KCNH8 FRMD4B PLEKHH1	6.88e-05	184	167	6	f6d6b3ddada66dae28d3306415bf4efe0934208a
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD4 CEP350 USP8 PHF3 UTRN GOLGA4	6.88e-05	184	167	6	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	CFAP47 ABCA13 TOGARAM2 ADGB CFAP206 DNAH5	7.09e-05	185	167	6	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 KLK6 KCNH8 PI16 FRMD4B PLEKHH1	7.09e-05	185	167	6	b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MATK ITGA7 TRRAP KDM2B PLCG1 GARRE1	7.30e-05	186	167	6	76cbc3610aedf8c19c17ad5faf6ef5e8980b6af5
ToppCell	COVID-19_Severe-Lymphoid_T/NK-CD8+_T_activated\|COVID-19_Severe / Disease group, lineage and cell class	MATK SYNE1 KIAA1671 SYNE2 IFI44L TTC38	7.52e-05	187	167	6	4c4c4406e16a15dedcd50bbcc2059d722a2e3d2c
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MATK SYNE1 SYNE2 IFI44L UTRN TTC38	7.52e-05	187	167	6	0bca79cea4886b66350c56c61859bd71e1e7a85c
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 KLK6 KCNH8 PI16 FRMD4B PLEKHH1	7.52e-05	187	167	6	b71d0cd91bc98e020757c1d071a13ad48d718bcf
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NPR1 MAP1B NXN KIAA1671 MAPK3 UTRN	7.52e-05	187	167	6	66ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	SGCG PPP1R12B ITGA7 TRDN GREB1L SVIL	7.75e-05	188	167	6	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	COPD-Lymphoid-NK\|COPD / Disease state, Lineage and Cell class	CDK17 MATK SYNE1 ATP8A1 SYNE2 TTC38	7.75e-05	188	167	6	c9a227c8e71b69929d43e9afb8306a95c8163778
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NPR1 CTTNBP2 PRICKLE1 SYNE1 NXN STXBP6	7.75e-05	188	167	6	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	COPD-Endothelial-VE_Capillary_A\|Endothelial / Disease state, Lineage and Cell class	INPP5A SYNE1 DENND2B KLHL5 STXBP6 KLK1	7.75e-05	188	167	6	1aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B CHD4 PABPC1 SERPINE2 SYNE2 AEBP2	7.75e-05	188	167	6	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 KLK6 KCNH8 PI16 FRMD4B PLEKHH1	7.75e-05	188	167	6	b04fd6a724c117eb9a979c29b91f90113feb7a5c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NPR1 CTTNBP2 PRICKLE1 SYNE1 NXN STXBP6	7.75e-05	188	167	6	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TFEB CDK18 KLK6 KCNH8 FRMD4B PLEKHH1	7.98e-05	189	167	6	b60c8a29d3169c4830fe63b01db90c57660fc239
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM2 SLC8A3 STXBP6 IRAK3 IGSF21 FMNL1	7.98e-05	189	167	6	7ccea2df93bb4b37417bbc8f6c85a61ece95211a
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	CDK17 FRMD4B KIAA1671 HIBCH IRAK3 GARRE1	7.98e-05	189	167	6	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	Neuroendocrine-neuroendo-2-Calca\|World / Class top	MAP1B SGCG SERPINE2 OLFM2 KLK1 FMNL1	7.98e-05	189	167	6	6baa9a74560121cc008bb8fa9b2b7a335b3aeee0
ToppCell	COVID-19_Mild-Treg\|COVID-19_Mild / Disease condition and Cell class	PI16 MCF2L2 CTTNBP2NL FRMD4B PDP1 HERC5	7.98e-05	189	167	6	f0fceb5f87ca260bfe038c0db3487a6d2e1b0a6e
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MATK SYNE1 KIAA1671 SYNE2 IFI44L TTC38	8.21e-05	190	167	6	b9182c84e44aa31684b5388cf3ef4fd1b9e51de4
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MATK SYNE1 KIAA1671 SYNE2 IFI44L TTC38	8.21e-05	190	167	6	88c092a5e78ccaddf406f8fff74376bb761b9790
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CDK17 HGF MAP1B SYNE1 DENND2B URB1	8.21e-05	190	167	6	1121eb607a984c59fbffe7220837fc178745aa55
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPR1 CTTNBP2 ABCA13 SYNE1 SYNE2 UTRN	8.21e-05	190	167	6	b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	MATK SYNE1 KIAA1671 SYNE2 IFI44L TTC38	8.21e-05	190	167	6	4b42a16902d7d1494f953cc88af1e761e76bdf2c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CDK17 HGF MAP1B SYNE1 DENND2B URB1	8.21e-05	190	167	6	048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CTTNBP2 MAP1B PI16 TRDN KIAA1671 SERPINE2	8.21e-05	190	167	6	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAP1B CHD4 KLHL5 AEBP2 UTRN GOLGA4	8.21e-05	190	167	6	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPR1 CTTNBP2 ABCA13 SYNE1 SYNE2 UTRN	8.21e-05	190	167	6	a5db902ad112a0c0a0a7f1a2e38718bb3bd11412
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MATK SYNE1 KIAA1671 SYNE2 IFI44L TTC38	8.21e-05	190	167	6	9501f0995f3d52be90c02b1aa0c7d184bd788c16
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CDK18 KLK6 KCNH8 PI16 FRMD4B PLEKHH1	8.21e-05	190	167	6	396b7225c2430db3dc55a3d0db70239b71987229
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	SGCG PPP1R12B TRDN GREB1L SVIL LIMCH1	8.45e-05	191	167	6	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	GBF1 FRYL URB1 ATP8A1 PRKDC EDRF1	8.45e-05	191	167	6	9454f642c3621370fa23640b631301346b300950
ToppCell	RA-09._Endothelium_I\|World / Chamber and Cluster_Paper	CDK17 SYNE1 CTTNBP2NL KIAA1671 SYNE2 GARRE1	8.45e-05	191	167	6	c8a0c2af119bc34a8f694a7d30642f28002c84b9
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SYNE1 CEP350 PHF3 SYNE2 UTRN DYNC1H1 GOLGA4	3.04e-07	49	100	7	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Computational	Neighborhood of SS18	PDXDC1 RBBP8 CHD3 FRYL NFATC2IP	2.68e-04	62	100	5	MORF_SS18
Computational	Neighborhood of RAP1A	RBBP8 PEX3 CHD3 FRYL CEP350 DDX46 UTRN	3.20e-04	140	100	7	MORF_RAP1A
Computational	Neighborhood of ERBB2IP	FRYL CEP350 MTMR4 GARRE1 VPS13B	3.35e-04	65	100	5	GCM_ERBB2IP
Drug	Chlorphensin carbamate [886-74-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A	TFEB CDK17 CDK18 TCF3 MATK RHOBTB2 VPS13A ATXN10 EDRF1 HERC5	2.02e-06	198	166	10	2279_DN
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	TFEB MAP1B ITGA7 NXN FRMD4B SERPINE2 PDP1 RHOBTB2 LIMCH1	6.59e-06	178	166	9	6454_UP
Drug	Sparteine (-) [90-39-1]; Down 200; 17uM; MCF7; HT_HG-U133A	CACNA1D UTP14A STRN PHF3 BTBD7 ATXN10 TTC38 EDRF1 VPS13B	1.07e-05	189	166	9	2790_DN
Drug	Carbarsone [121-59-5]; Down 200; 15.4uM; MCF7; HT_HG-U133A	CDK17 ZSWIM8 TCF3 UTP14A STRN PHF3 BTBD7 LIMCH1 MAPK13	1.21e-05	192	166	9	4110_DN
Drug	Naringin hydrate [11032-30-7]; Down 200; 6.6uM; MCF7; HT_HG-U133A	CDK17 SGCG BTBD7 SVIL CNGB3 LIMCH1 UTRN TTC38 VPS13B	1.37e-05	195	166	9	3286_DN
Drug	Hymecromone [90-33-5]; Up 200; 22.8uM; MCF7; HT_HG-U133A	HTR1F SYNE1 PEX3 CEP350 KLHL25 CLCN1 CHD5 LIMCH1 KLK1	1.43e-05	196	166	9	3383_UP
Drug	Pramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A	MATK UTP14A FRMD4B FBXO22 KLHL25 BTBD7 CNGB3 PLCG1 EDRF1	1.49e-05	197	166	9	3894_DN
Drug	Naloxone hydrochloride [357-08-4]; Down 200; 11uM; MCF7; HT_HG-U133A	CDK17 TCF3 UTP14A PCDHA6 DENND2B URB1 KLHL25 PHF3 BTBD7	1.55e-05	198	166	9	5243_DN
Disease	Cohen syndrome (implicated_via_orthology)	VPS13A VPS13B	9.18e-05	3	164	2	DOID:0111590 (implicated_via_orthology)
Disease	severe combined immunodeficiency (implicated_via_orthology)	RAG1 PRKDC	9.18e-05	3	164	2	DOID:627 (implicated_via_orthology)
Disease	Colorectal Carcinoma	TCF3 MAP1B ABCA13 SYNE1 MCF2L2 LAMB3 ISLR NXN CHD5 VPS13A OLFM2 IGSF21 EDRF1	1.60e-04	702	164	13	C0009402
Disease	FEV/FEC ratio	CACNA1D CTTNBP2 PABPC4 UTP14A SERTAD2 MEI1 DENND2B CTTNBP2NL USP8 KLHL25 GLIS2 SVIL SYNE2 AEBP2 ATXN10 MAPK3 DNAH5 PTCD3	1.74e-04	1228	164	18	EFO_0004713
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	1.83e-04	4	164	2	cv:CN293514
Disease	arthrogryposis multiplex congenita (is_implicated_in)	SYNE1 VPS33B	1.83e-04	4	164	2	DOID:0080954 (is_implicated_in)
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	3.04e-04	5	164	2	C1450051
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	3.04e-04	5	164	2	C0410190
Disease	lissencephaly (implicated_via_orthology)	CDK17 CDK18 DYNC1H1	4.47e-04	27	164	3	DOID:0050453 (implicated_via_orthology)
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	4.54e-04	6	164	2	cv:C0410189
Disease	quality of life during menstruation measurement, breast pressure measurement	MAP1B ANKRD17	4.54e-04	6	164	2	EFO_0009366, EFO_0009393
Disease	Congenital muscular dystrophy (disorder)	ITGA7 SYNE2	4.54e-04	6	164	2	C0699743
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	4.54e-04	6	164	2	C0410189
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	6.33e-04	7	164	2	C0751337
Disease	autosomal dominant nonsyndromic deafness (is_implicated_in)	MAP1B GREB1L	1.63e-03	11	164	2	DOID:0050564 (is_implicated_in)
Disease	PEROXISOME BIOGENESIS DISORDER 1A (ZELLWEGER)	PEX3 PEX5	1.63e-03	11	164	2	C4721541
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 SYNE2	1.95e-03	12	164	2	DOID:11726 (implicated_via_orthology)
Disease	Infantile Refsum Disease (disorder)	PEX3 PEX5	2.30e-03	13	164	2	C0282527
Disease	Nephronophthisis	GLIS2 ATXN10	2.30e-03	13	164	2	C0687120
Disease	triacylglycerol 46:2 measurement	GTF3C2 MYO3B	2.67e-03	14	164	2	EFO_0010402
Disease	Peroxisome biogenesis disorders	PEX3 PEX5	3.07e-03	15	164	2	C1832200
Disease	response to peritoneal dialysis, peritoneal solute transfer rate	SERTAD2 KDM2B	3.07e-03	15	164	2	EFO_0600089, EFO_0600090
Disease	Adrenoleukodystrophy, Neonatal	PEX3 PEX5	3.07e-03	15	164	2	C0282525
Disease	fatty acid measurement	PDXDC1 ANKRD31 ATP8A2 TPTE2 PABPC4 GREB1L NAA25 MYO3B	3.15e-03	436	164	8	EFO_0005110
Disease	Zellweger Syndrome	PEX3 PEX5	3.50e-03	16	164	2	C0043459
Disease	Intellectual Disability	GALT MAP1B ATP8A2 SYNE1 CHD3 TRRAP RHOBTB2 DYNC1H1	3.66e-03	447	164	8	C3714756
Disease	Tourette syndrome, schizophrenia	CCDC92 PHF3	4.43e-03	18	164	2	EFO_0004895, MONDO_0005090
Disease	sphingomyelin measurement	PDXDC1 PPP1R12B PABPC4 FRMD4B SYNE2 DYNC1H1	4.73e-03	278	164	6	EFO_0010118
Disease	Cleft palate, cleft lip	MAP1B ABCA13 NAA25 PDP1 LIMCH1 VPS13B	4.81e-03	279	164	6	EFO_0003959, HP_0000175
Disease	peripheral neuropathy, response to docetaxel trihydrate	ATP8A2 TRPM2	4.93e-03	19	164	2	EFO_0003100, GO_1902519
Disease	inferior parietal cortex volume measurement	PRICKLE1 DENND2B	4.93e-03	19	164	2	EFO_0010307
Disease	triglyceride measurement, body mass index	PDXDC1 CCDC92	4.93e-03	19	164	2	EFO_0004340, EFO_0004530
Disease	Squamous cell carcinoma	HGF INPP5A PRKDC MAPK3	5.15e-03	124	164	4	C0007137
Disease	Severe Combined Immunodeficiency	RAG1 PRKDC	5.46e-03	20	164	2	C0085110
Disease	CCL5 measurement	SYNE1 ATXN10 UTRN	5.48e-03	64	164	3	EFO_0005117

Protein segments in the cluster

Peptide	Gene	Start	Entry
SLDPKMSLTGARELL	PI16	336	Q6UXB8
SDPLMALQRDFETLK	CTTNBP2NL	51	Q9P2B4
TDMADLEELSRLSPL	AEBP2	6	Q6ZN18
SLLDMASKIREDPLF	CWC25	126	Q9NXE8
VMDKPLDLSDRFSAI	RBBP8	486	Q99708
ELLSDMKADVTRLPS	CHD5	1866	Q8TDI0
LTSEELLNRMPSKIL	HTR1F	11	P30939
TSPRLIRKALEFMDL	ADGB	1526	Q8N7X0
EDVSKRLSLPMDIRL	CDK18	91	Q07002
LLDLMIAKITSDEPL	ATXN10	246	Q9UBB4
DLRDLATSMDSIVKL	ABCA13	2511	Q86UQ4
SSPDAFRTLMLLALE	NPR1	246	P16066
DLENPMLETASKLLL	ANKRD17	141	O75179
MDDEDTLLPRKLQAA	DENND2B	981	P78524
KLVDPERDMSLRLNE	CAPRIN1	191	Q14444
VLARMDKAVFPSLDD	GKN3P	81	P0CG01
MAADQRPKADTLALR	PHYKPL	1	Q8IUZ5
PATSDIKDVDSLMRI	ATP8A1	201	Q9Y2Q0
MALILLKEDSLDATR	ATP8A2	726	Q9NTI2
TAILEKAANDPLMRA	CFAP206	241	Q8IYR0
EVIARPASLSNDKLM	CKAP2	321	Q8WWK9
SPLIAEREAMKSSEL	RAG1	676	P15918
ALDFSAMLPKIAVRD	RBM44	406	Q6ZP01
RLKVMLADSPREESN	RBM45	456	Q8IUH3
ELKDRMTELLPLSSV	OLFM2	121	O95897
SARIKMEEDALLSDP	ARHGAP36	461	Q6ZRI8
KLAMLEEDLLALKSP	HIBCH	221	Q6NVY1
MLLASILTPSVEADK	PCDHGB7	786	Q9Y5F8
MLESPESLRSKVDEA	PABPC1	596	P11940
LAELVPRLFRMASKD	PCDHA6	56	Q9UN73
ELVSDFDRKELMNPL	ANKRD31	241	Q8N7Z5
FDRKELMNPLSDSLS	ANKRD31	246	Q8N7Z5
RTSMETALALEKLFP	FBXO22	126	Q8NEZ5
ELLHMLESPESLRSK	PABPC4	601	Q13310
PRSELLNELMDSAKV	PTCD3	606	Q96EY7
LESMPSVRLLLLKDN	LRTM1	166	Q9HBL6
REREALSADPKLSLM	MATK	106	P42679
KELEAERSLMSSPED	MAP1B	821	P46821
DRIAESLDMPKASLL	MAGEE2	166	Q8TD90
LIMDDDRTVDPLLSK	MAP9	321	Q49MG5
LMLLRLTEPADTITD	KLK1	121	P06870
RPLSMDLTARFENKE	KIAA1671	281	Q9BY89
ADASPSLNREEVMKL	EDRF1	1141	Q3B7T1
KILEREDARLMFTSP	GOLGA4	2211	Q13439
ARASLERLVKEMAPL	FYCO1	441	Q9BQS8
SDLELDPMKDILILS	IFI44L	406	Q53G44
ADLLPKLKSMALADR	DDX55	401	Q8NHQ9
LLKMDSNELTFIPRD	ISLR	126	O14498
TAELPRSMLSTEDLL	MCF2L2	226	Q86YR7
ILMSPSAKELVLRSE	INPP5A	351	Q14642
LLMADQDSPLDLTVR	LCOR	56	Q96JN0
IKLLNETRDMLESPD	PEX3	261	P56589
SRAPQTFKMDDLLAE	PEX5	76	P50542
MDASLEKIADPTLAE	PDXDC1	1	Q6P996
MDASLEKIADPTLAE	PDXDC2P	1	Q6P474
MAEPLEKLLSRSLQR	FRYL	36	O94915
RASPQAADLLEKMLE	MAPK13	276	O15264
PLLASIARELSKMAQ	LRRC14B	266	A6NHZ5
PADSMLLDLERTLML	MIGA2	256	Q7L4E1
TRDMIDNLLSPDLID	SERPINE2	161	P07093
SKALDLLDRMLTFNP	MAPK3	301	P27361
ISMEDLNKRLSLPAD	CDK17	136	Q00537
LMKLARPAVLDDFVS	HGF	581	P14210
AATRAKLRPSMDEVL	IRAK3	426	Q9Y616
MHSLDEPLDLKLSIT	GLIS2	1	Q9BZE0
LALSSDKIAALRMPL	COMMD8	126	Q9NX08
PKNVARMLALALAES	ARHGAP32	1036	A7KAX9
SSLRPLLNKDMSSEE	GREB1L	1266	Q9C091
LPASEIAKLLASDDM	KLHL5	361	Q96PQ7
DHERLSKMLSLPEEL	PDP1	496	Q9P0J1
ATEAMAPDILARKLA	PPP1R2	91	P41236
SLDRLPKTRSMDDLL	MTMR4	601	Q9NYA4
MLESPESLRSKVDEA	PABPC3	591	Q9H361
EKMLALTLAKADSPR	MEI1	991	Q5TIA1
LALLMKEAELRGSPS	TM7SF2	206	O76062
LLDQMPSLEDLKELS	HERC5	796	Q9UII4
DLKPEQSVRDSMDSL	PRICKLE1	526	Q96MT3
RMLRLSLNIDPDAKV	HSP90B1	741	P14625
KIPSARSLDEIAMDL	FRMD4B	366	Q9Y2L6
PFRSLLHRDLDDTKM	IGSF21	211	Q96ID5
RMSAELTVLDEPLKF	IGSF22	316	Q8N9C0
LKDAQMRDLLSPPTD	KDM2B	1186	Q8NHM5
SSEALLMADERTKLI	KLHL25	251	Q9H0H3
NLKMLISAASPDIRD	E2F7	86	Q96AV8
MATAATSPALKRLDL	COG1	1	Q8WTW3
FDVDTLSKSELRMLL	CTTNBP2	31	Q8WZ74
AESRKLLLREPVDAM	CCDC92	226	Q53HC0
LLSDMKADVTRLPAT	CHD3	1871	Q12873
ELTPAERDDLASIMK	GALT	266	P07902
LKEDPATMSLLQRSL	GARRE1	456	O15063
HSDRLLELKSPTELM	CEP350	2451	Q5VT06
ARPEARTLQKDMADL	BTBD7	121	Q9P203
LRANSPTMDKLLADS	FMNL1	946	O95466
MKDFPLNDLLSATEL	DYNC1H1	336	Q14204
DLLSEAIPESLKNML	GBF1	1661	Q92538
FLLTRLNDPKMSETE	KCMF1	291	Q9P0J7
DLTMHPLKALEDLSE	KLF18	81	A0A0U1RQI7
KLVALRLEMSSLPDL	LAMB3	766	Q13751
ISPANEKTLLSEDMR	CCDC174	196	Q6PII3
LRKDSASRLVPEVML	ITGA7	341	Q13683
AMEALARRILSKPIE	DDX46	566	Q7L014
LSDMKADVTRLPATI	CHD4	1861	Q14839
SADPELALALRVSME	PSMD4	211	P55036
KDMLLAFPNDRAATI	CFAP47	581	Q6ZTR5
LSRLGPSLRDKDLEM	PPRC1	66	Q5VV67
LKDMDPSELVEALRT	ATP4A	681	P20648
IMLSSAALAAEDPIR	CACNA1D	896	Q01668
MESPKEALSAQSRDL	FOCAD	1761	Q5VW36
PIKDLDDIRIAMAAL	DNAH5	1246	Q8TE73
SLDHIKELLMETRSP	ERCC6L	386	Q2NKX8
KELLMETRSPLAELG	ERCC6L	391	Q2NKX8
ALDIKSADPEVMLLT	ERCC6L	1226	Q2NKX8
LLAQMRKDTDDIESP	LIMCH1	156	Q9UPQ0
PRNLSLMDKLLDLDD	FAM149B1	366	Q96BN6
LDLDDKLLMRPGSST	FAM149B1	376	Q96BN6
DPLRVSSRDKLTEMA	FUNDC2	26	Q9BWH2
SMANPEELDKLISDR	FOXN4	296	Q96NZ1
RTELEMLSDKSLSLP	UTRN	2141	P46939
DMLANLRDVDELPSL	STRN	356	O43815
PSLSKKDLDLMLLDD	TFEB	426	P19484
SLMPKLIDLEDSADV	REPS1	366	Q96D71
RPDMQLESDLKLDRL	SVIL	1256	O95425
LKFSSMAPDLDRLNE	SYNE1	7401	Q8NF91
NLTDVSPDLDIRLKM	SYNE2	836	Q8WXH0
ALESFAKMIPLLRES	TOGARAM2	826	Q6ZUX3
AAPLLTILDMSARAK	NXN	391	Q6DKJ4
SPDLDDMKLIILANR	RHOBTB2	566	Q9BYZ6
LEVSLSRDSPLKTLM	NFATC2IP	361	Q8NCF5
PFARAKDLSVLMDRL	URB1	1331	O60287
LSLTTKMDAEHPELR	SCRN1	191	Q12765
DLRLESPTRSLSMDA	SGCG	191	Q13326
RMLDESDLLKTLPTT	CNGB3	491	Q9NQW8
LRAAQEMARKLSELP	CLCN1	671	P35523
LLTMSLERDLLDAEP	STK31	721	Q9BXU1
LERDLLDAEPMKELS	STK31	726	Q9BXU1
RALALPDKVLLEDAM	PRR22	276	Q8IZ63
AISKEIFAPLDERML	STXBP6	6	Q8NFX7
MSTDKAPLRQLLDAT	ZSWIM5	1101	Q9P217
KPRLLSSLDDAMSLF	VPS13A	551	Q96RL7
ITEDLSLADLMPRVK	MTREX	86	P42285
RMAPVGTDKELSDLL	TCF3	6	P15923
PQESRADDSKLMDSL	SERTAD2	211	Q14140
LKSPDADSDQLFRMV	RYR3	3281	Q15413
DAMVDLLDLDPLKRS	TRPM2	1156	O94759
IRMSPEELASKELAA	PHF3	1011	Q92576
KTMDLPFLEASTLRA	PLCG1	226	P19174
AMEPELADTSALKAA	SH2B2	96	O14492
PVEKASLRAMSLEEA	UTP14A	206	Q9BVJ6
LTNEDFRKLLMTPRA	IK	31	Q13123
RDLLPSSAMIKDLSQ	nan	381	Q6ZUG5
DDFMLVIRSIPDKSS	PLEKHH1	1281	Q9ULM0
DSPLETKMAVLALLA	PRKDC	1636	P78527
PDLAEMSLDDSSLAL	ZSWIM8	616	A7E2V4
NVARSLLMERDALKP	TTC38	436	Q5R3I4
SDPLKLVRDAMEETT	TRDN	86	Q13061
MSLDKAPLRQLLDAT	ZSWIM6	1131	Q9HCJ5
IADMALDPAKKLLLT	WDR55	171	Q9H6Y2
NESRKPESLLAPDLM	VPS13B	911	Q7Z7G8
LSRLEQPDLSSEMSK	GTF3C2	76	Q8WUA4
AALVSPISKSMLERL	TPTE2	31	Q6XPS3
ALQRALEMSLAETKP	ZFAND2B	201	Q8WV99
LDPEKQADMLDSLRI	TRRAP	1816	Q9Y4A5
FSPTLMLTDEEKARI	USP8	451	P40818
ELPDFSMLKRLARDQ	VPS33B	11	Q9H267
LKCPMDLLARDAPDT	ZP4	126	Q12836
DIMLLRLARPAKLSE	KLK6	106	Q92876
LLKDFPDELRSDITM	KCNH8	526	Q96L42
SLMALADFDEPKRST	MYMK	81	A6NI61
LLLSPDVTDRKLTME	SLC8A3	631	P57103
SLAAVKILDPVSDMD	MYO3B	51	Q8WXR4
LKPMSIISLLDEESR	MYO7B	501	Q6PIF6
LAESIKSMNLRPEED	NAA25	631	Q14CX7
SDLAEEPAMKDLLLE	PPP1R12B	161	O60237