Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	peptide lactyltransferase (CoA-dependent) activity	CREBBP EP300	1.35e-05	2	74	2	GO:0120300
GeneOntologyMolecularFunction	histone H3K27 acetyltransferase activity	CREBBP EP300	1.35e-05	2	74	2	GO:0044017
GeneOntologyMolecularFunction	histone H3K18 acetyltransferase activity	CREBBP EP300	4.05e-05	3	74	2	GO:0043993
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF600 ZBTB38 ZNF256 ZSCAN18 ZNF202 ZNF74 ZNF736 ZSCAN25 APP ZNF763 CREBBP ZNF416 ZNF891 EP300 ZNF572 ZNF445	7.10e-05	1459	74	16	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF600 ZBTB38 ZNF256 ZSCAN18 ZNF202 ZNF74 ZNF736 ZSCAN25 APP ZNF763 ZNF416 EP300 ZNF572 ZNF445	1.66e-04	1244	74	14	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF600 ZBTB38 ZNF256 ZSCAN18 ZNF202 ZNF74 ZNF736 ZSCAN25 APP ZNF763 ZNF416 EP300 ZNF572 ZNF445	2.08e-04	1271	74	14	GO:0000987
GeneOntologyMolecularFunction	myosin light chain binding	SPATA6L CXCR4	3.74e-04	8	74	2	GO:0032027
HumanPheno	Aortic isthmus hypoplasia	CREBBP EP300	1.18e-05	2	18	2	HP:0034227
HumanPheno	Plantar crease between first and second toes	CREBBP EP300	1.18e-05	2	18	2	HP:0008107
HumanPheno	High axial triradius	CREBBP EP300	1.18e-05	2	18	2	HP:0001042
HumanPheno	Spinal cord compression	NEPRO HABP2 CREBBP EP300	1.36e-05	44	18	4	HP:0002176
HumanPheno	Humoral immunodeficiency	CREBBP EP300	3.53e-05	3	18	2	HP:0005363
HumanPheno	Prominent nasal septum	CREBBP EP300	3.53e-05	3	18	2	HP:0005322
HumanPheno	Radial deviation of thumb terminal phalanx	CREBBP EP300	3.53e-05	3	18	2	HP:0005895
HumanPheno	Laryngeal cartilage malformation	CREBBP EP300	3.53e-05	3	18	2	HP:0008752
HumanPheno	Phobia	CREBBP EP300	3.53e-05	3	18	2	HP:5200232
HumanPheno	Agoraphobia	CREBBP EP300	3.53e-05	3	18	2	HP:0000756
HumanPheno	Trichiasis	CREBBP EP300	7.05e-05	4	18	2	HP:0001128
HumanPheno	Widened distal phalanges	CREBBP EP300	7.05e-05	4	18	2	HP:0006200
HumanPheno	Visceral hemangioma	CREBBP EP300	7.05e-05	4	18	2	HP:0410266
HumanPheno	Talon cusp	CREBBP EP300	7.05e-05	4	18	2	HP:0011087
HumanPheno	Vascular ring	CREBBP EP300	7.05e-05	4	18	2	HP:0010775
HumanPheno	Hepatic hemangioma	CREBBP EP300	7.05e-05	4	18	2	HP:0031207
HumanPheno	Papillary cystadenoma of the epididymis	CREBBP EP300	1.17e-04	5	18	2	HP:0009715
HumanPheno	Supernumerary cusp	CREBBP EP300	1.17e-04	5	18	2	HP:0033777
HumanPheno	Epididymal neoplasm	CREBBP EP300	1.17e-04	5	18	2	HP:0030421
HumanPheno	Broad eyebrow	NEPRO CREBBP EP300	1.28e-04	29	18	3	HP:0011229
HumanPheno	Abnormal epididymis morphology	CCR1 CREBBP EP300	1.42e-04	30	18	3	HP:0009714
HumanPheno	Large foramen magnum	CREBBP EP300	1.75e-04	6	18	2	HP:0002700
HumanPheno	Deviated nasal septum	CREBBP EP300	2.45e-04	7	18	2	HP:0004411
HumanPheno	Pilomatrixoma	CREBBP EP300	4.18e-04	9	18	2	HP:0030434
HumanPheno	Cervical cord compression	CREBBP EP300	4.18e-04	9	18	2	HP:0002341
HumanPheno	Frontal hirsutism	CREBBP EP300	5.22e-04	10	18	2	HP:0011335
HumanPheno	Abnormal subclavian artery morphology	CREBBP EP300	6.37e-04	11	18	2	HP:0031251
HumanPheno	Dislocated radial head	BMP1 CREBBP EP300	8.21e-04	54	18	3	HP:0003083
HumanPheno	Facial grimacing	CREBBP EP300	8.99e-04	13	18	2	HP:0000273
HumanPheno	Keloids	CREBBP EP300	8.99e-04	13	18	2	HP:0010562
HumanPheno	Neoplasm of the genitourinary tract	CXCR4 HABP2 CREBBP TRIM37 EP300	9.12e-04	228	18	5	HP:0007379
HumanPheno	Abnormality of the radial head	BMP1 CREBBP EP300	9.62e-04	57	18	3	HP:0003995
HumanPheno	Parietal foramina	CREBBP EP300	1.05e-03	14	18	2	HP:0002697
HumanPheno	Duplication of phalanx of hallux	CREBBP EP300	1.05e-03	14	18	2	HP:0010066
HumanPheno	Hypoplastic aortic arch	CREBBP EP300	1.05e-03	14	18	2	HP:0012304
HumanPheno	Social and occupational deterioration	CREBBP EP300	1.21e-03	15	18	2	HP:0007086
HumanPheno	Duplication of phalanx of toe	CREBBP EP300	1.21e-03	15	18	2	HP:0010181
HumanPheno	Abnormality of the humeroradial joint	BMP1 CREBBP EP300	1.23e-03	62	18	3	HP:0100744
Domain	-	ZNF600 ZBTB38 ZNF155 ZNF256 ZBTB21 ZSCAN18 ZNF202 ZNF74 ZNF736 ZSCAN25 ZNF763 ZNF416 ZNF891 ZNF572 ZNF445	4.51e-08	679	73	15	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF600 ZBTB38 ZNF155 ZNF256 ZBTB21 ZSCAN18 ZNF202 ZNF74 ZNF736 ZSCAN25 ZNF763 ZNF416 ZNF891 ZNF572 ZNF445	6.00e-08	694	73	15	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF600 ZBTB38 ZNF155 ZNF256 ZBTB21 ZSCAN18 ZNF202 ZNF74 ZNF736 ZSCAN25 ZNF763 ZNF416 ZNF891 ZNF572 ZNF445	2.50e-07	775	73	15	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF600 ZBTB38 ZNF155 ZNF256 ZBTB21 ZSCAN18 ZNF202 ZNF74 ZNF736 ZSCAN25 ZNF763 ZNF416 ZNF891 ZNF572 ZNF445	2.59e-07	777	73	15	PS00028
Domain	Znf_C2H2-like	ZNF600 ZBTB38 ZNF155 ZNF256 ZBTB21 ZSCAN18 ZNF202 ZNF74 ZNF736 ZSCAN25 ZNF763 ZNF416 ZNF891 ZNF572 ZNF445	3.52e-07	796	73	15	IPR015880
Domain	zf-C2H2	ZNF600 ZBTB38 ZNF155 ZNF256 ZBTB21 ZNF202 ZNF74 ZNF736 ZSCAN25 ZNF763 ZNF416 ZNF891 ZNF572 ZNF445	4.00e-07	693	73	14	PF00096
Domain	Znf_C2H2	ZNF600 ZBTB38 ZNF155 ZNF256 ZBTB21 ZSCAN18 ZNF202 ZNF74 ZNF736 ZSCAN25 ZNF763 ZNF416 ZNF891 ZNF572 ZNF445	4.07e-07	805	73	15	IPR007087
Domain	ZnF_C2H2	ZNF600 ZBTB38 ZNF155 ZNF256 ZBTB21 ZSCAN18 ZNF202 ZNF74 ZNF736 ZSCAN25 ZNF763 ZNF416 ZNF891 ZNF572 ZNF445	4.26e-07	808	73	15	SM00355
Domain	KRAB	ZNF155 ZNF256 ZNF202 ZNF74 ZNF736 ZSCAN25 ZNF763 ZNF416 ZNF891 ZNF445	1.65e-06	369	73	10	SM00349
Domain	KRAB	ZNF155 ZNF256 ZNF202 ZNF74 ZNF736 ZSCAN25 ZNF763 ZNF416 ZNF891 ZNF445	1.69e-06	370	73	10	IPR001909
Domain	zf-C2H2_6	ZNF600 ZNF155 ZNF256 ZNF736 ZNF763 ZNF416 ZNF891 ZNF572 ZNF445	3.61e-06	314	73	9	PF13912
Domain	KRAB	ZNF155 ZNF256 ZNF202 ZNF74 ZNF736 ZNF763 ZNF416 ZNF891 ZNF445	1.04e-05	358	73	9	PS50805
Domain	KRAB	ZNF155 ZNF256 ZNF202 ZNF74 ZNF736 ZNF763 ZNF416 ZNF891 ZNF445	1.04e-05	358	73	9	PF01352
Domain	Nuc_rcpt_coact_CREBbp	CREBBP EP300	1.51e-05	2	73	2	IPR014744
Domain	HAT_KAT11	CREBBP EP300	1.51e-05	2	73	2	PF08214
Domain	KIX	CREBBP EP300	1.51e-05	2	73	2	PS50952
Domain	ZnF_TAZ	CREBBP EP300	1.51e-05	2	73	2	SM00551
Domain	CBP_P300_HAT	CREBBP EP300	1.51e-05	2	73	2	IPR031162
Domain	DUF902	CREBBP EP300	1.51e-05	2	73	2	PF06001
Domain	-	CREBBP EP300	1.51e-05	2	73	2	1.20.1020.10
Domain	RING_CBP-p300	CREBBP EP300	1.51e-05	2	73	2	IPR010303
Domain	-	CREBBP EP300	1.51e-05	2	73	2	1.10.1630.10
Domain	Creb_binding	CREBBP EP300	1.51e-05	2	73	2	PF09030
Domain	-	CREBBP EP300	1.51e-05	2	73	2	1.10.246.20
Domain	zf-TAZ	CREBBP EP300	1.51e-05	2	73	2	PF02135
Domain	ZF_TAZ	CREBBP EP300	1.51e-05	2	73	2	PS50134
Domain	Histone_AcTrfase_Rtt109/CBP	CREBBP EP300	1.51e-05	2	73	2	IPR013178
Domain	KAT11	CREBBP EP300	1.51e-05	2	73	2	SM01250
Domain	Znf_TAZ	CREBBP EP300	1.51e-05	2	73	2	IPR000197
Domain	KIX_dom	CREBBP EP300	1.51e-05	2	73	2	IPR003101
Domain	KIX	CREBBP EP300	1.51e-05	2	73	2	PF02172
Domain	CBP_P300_HAT	CREBBP EP300	1.51e-05	2	73	2	PS51727
Domain	SCAN	ZSCAN18 ZNF202 ZSCAN25 ZNF445	6.76e-05	56	73	4	SM00431
Domain	SCAN_BOX	ZSCAN18 ZNF202 ZSCAN25 ZNF445	7.77e-05	58	73	4	PS50804
Domain	SCAN	ZSCAN18 ZNF202 ZSCAN25 ZNF445	7.77e-05	58	73	4	PF02023
Domain	SCAN_dom	ZSCAN18 ZNF202 ZSCAN25 ZNF445	7.77e-05	58	73	4	IPR003309
Domain	Retrov_capsid_C	ZSCAN18 ZNF202 ZSCAN25 ZNF445	8.31e-05	59	73	4	IPR008916
Domain	Nuc_rcpt_coact	CREBBP EP300	2.24e-04	6	73	2	IPR009110
Domain	PKD	PKD1 SORCS3	3.12e-04	7	73	2	PF00801
Domain	PKD	PKD1 SORCS3	8.10e-04	11	73	2	PS50093
Domain	PKD_dom	PKD1 SORCS3	8.10e-04	11	73	2	IPR000601
Domain	-	PKD1 SORCS3	8.10e-04	11	73	2	2.60.40.670
Domain	Oxysterol-bd	OSBPL7 OSBPL11	9.70e-04	12	73	2	IPR000648
Domain	Oxysterol-bd_CS	OSBPL7 OSBPL11	9.70e-04	12	73	2	IPR018494
Domain	Oxysterol_BP	OSBPL7 OSBPL11	9.70e-04	12	73	2	PF01237
Domain	OSBP	OSBPL7 OSBPL11	9.70e-04	12	73	2	PS01013
Domain	Dynein_heavy_chain_D4_dom	DNAH14 DNAH11	1.33e-03	14	73	2	IPR024317
Domain	Dynein_HC_stalk	DNAH14 DNAH11	1.33e-03	14	73	2	IPR024743
Domain	MT	DNAH14 DNAH11	1.33e-03	14	73	2	PF12777
Domain	AAA_8	DNAH14 DNAH11	1.33e-03	14	73	2	PF12780
Domain	DHC_fam	DNAH14 DNAH11	1.53e-03	15	73	2	IPR026983
Domain	Dynein_heavy_dom	DNAH14 DNAH11	1.53e-03	15	73	2	IPR004273
Domain	Dynein_heavy	DNAH14 DNAH11	1.53e-03	15	73	2	PF03028
Domain	Chemokine_rcpt	CXCR4 CCR1	1.75e-03	16	73	2	IPR000355
Domain	LH2	PKD1 ALOX5	2.21e-03	18	73	2	SM00308
Domain	ZZ	CREBBP EP300	2.21e-03	18	73	2	PF00569
Domain	ZF_ZZ_2	CREBBP EP300	2.21e-03	18	73	2	PS50135
Domain	ZF_ZZ_1	CREBBP EP300	2.21e-03	18	73	2	PS01357
Domain	Znf_ZZ	CREBBP EP300	2.47e-03	19	73	2	IPR000433
Domain	ZnF_ZZ	CREBBP EP300	2.47e-03	19	73	2	SM00291
Domain	PLAT	PKD1 ALOX5	3.02e-03	21	73	2	PS50095
Domain	-	PKD1 ALOX5	3.02e-03	21	73	2	2.60.60.20
Domain	PLAT	PKD1 ALOX5	3.02e-03	21	73	2	PF01477
Domain	PLAT/LH2_dom	PKD1 ALOX5	3.02e-03	21	73	2	IPR001024
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF600 ZNF155 ZNF256 ZNF202 ZNF74 NCBP1 ZNF736 ZSCAN25 MLST8 THOC3 CREBBP ZNF416 EP300 RBX1 ZNF445	3.46e-05	1387	48	15	M734
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	1.13e-04	5	48	2	MM1575
Pathway	REACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES	CREBBP EP300	1.13e-04	5	48	2	M48020
Pathway	REACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES	CREBBP EP300	1.13e-04	5	48	2	M48023
Pathway	REACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION	CREBBP EP300	1.13e-04	5	48	2	M27228
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP EP300	1.69e-04	6	48	2	M22062
Pathway	WP_TYPE_2_PAPILLARY_RENAL_CELL_CARCINOMA	CREBBP EP300 RBX1	2.06e-04	34	48	3	M39771
Pathway	REACTOME_EVASION_BY_RSV_OF_HOST_INTERFERON_RESPONSES	CREBBP EP300 RBX1	2.25e-04	35	48	3	M48246
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP EP300	2.36e-04	7	48	2	MM1573
Pathway	REACTOME_HSF1_DEPENDENT_TRANSACTIVATION	MLST8 CREBBP EP300	2.87e-04	38	48	3	M27255
Pathway	BIOCARTA_PPARG_PATHWAY	CREBBP EP300	3.14e-04	8	48	2	M22058
Pathway	REACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES	CREBBP EP300	3.14e-04	8	48	2	M48022
Pathway	REACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION	CREBBP EP300	3.14e-04	8	48	2	M48024
Pathway	REACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES	CREBBP EP300	3.14e-04	8	48	2	M46443
Pathway	KEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY	CREBBP EP300	4.03e-04	9	48	2	M47451
Pathway	REACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION	CREBBP EP300	5.02e-04	10	48	2	M27945
Pathway	REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	CREBBP EP300 RBX1	5.75e-04	48	48	3	M611
Pathway	REACTOME_SIGNALING_BY_NOTCH3	WWP2 CREBBP EP300	6.12e-04	49	48	3	M618
Pathway	BIOCARTA_CARM1_PATHWAY	CREBBP EP300	6.12e-04	11	48	2	MM1521
Pathway	REACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES	CREBBP EP300	6.12e-04	11	48	2	M48021
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR	CREBBP EP300	6.12e-04	11	48	2	M26924
Pathway	BIOCARTA_CARM1_PATHWAY	CREBBP EP300	7.33e-04	12	48	2	M7968
Pathway	REACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS	CREBBP EP300	7.33e-04	12	48	2	M27765
Pathway	REACTOME_KEAP1_NFE2L2_PATHWAY	CREBBP MUL1 EP300 RBX1	8.48e-04	125	48	4	M45021
Pathway	REACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER	CREBBP EP300 RBX1	1.00e-03	58	48	3	M29616
Pathway	REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	CREBBP EP300	1.01e-03	14	48	2	M27808
Pathway	KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS	WWP2 PRPF19 TRIM37 RBX1	1.13e-03	135	48	4	M15247
Pathway	BIOCARTA_RELA_PATHWAY	CREBBP EP300	1.16e-03	15	48	2	MM1339
Pathway	BIOCARTA_RELA_PATHWAY	CREBBP EP300	1.16e-03	15	48	2	M10183
Pathway	BIOCARTA_PITX2_PATHWAY	CREBBP EP300	1.16e-03	15	48	2	MM1439
Pathway	REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY	CREBBP EP300	1.16e-03	15	48	2	M953
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS	CREBBP EP300	1.32e-03	16	48	2	M27121
Pathway	BIOCARTA_IL7_PATHWAY	CREBBP EP300	1.32e-03	16	48	2	M1296
Pathway	BIOCARTA_IL7_PATHWAY	CREBBP EP300	1.32e-03	16	48	2	MM1420
Pathway	BIOCARTA_PITX2_PATHWAY	CREBBP EP300	1.32e-03	16	48	2	M8516
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES	CREBBP EP300	1.32e-03	16	48	2	M27940
Pathway	PID_HIF1_TFPATHWAY	CXCR4 CREBBP EP300	1.46e-03	66	48	3	M255
Pathway	BIOCARTA_TGFB_PATHWAY	CREBBP EP300	1.49e-03	17	48	2	MM1509
Pathway	REACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA	CREBBP EP300	1.49e-03	17	48	2	M48025
Pathway	WP_UROTENSINIIMEDIATED_SIGNALING	CREBBP ALOX5 EP300	1.66e-03	69	48	3	M48052
Pathway	REACTOME_RORA_ACTIVATES_GENE_EXPRESSION	CREBBP EP300	1.68e-03	18	48	2	M26942
Pathway	KEGG_WNT_SIGNALING_PATHWAY	WNT5B CREBBP EP300 RBX1	1.71e-03	151	48	4	M19428
Pathway	KEGG_RENAL_CELL_CARCINOMA	CREBBP EP300 RBX1	1.73e-03	70	48	3	M13266
Pathway	BIOCARTA_TGFB_PATHWAY	CREBBP EP300	1.87e-03	19	48	2	M18933
Pathway	REACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES	CREBBP EP300	1.87e-03	19	48	2	M46442
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	ZNF202 NCBP1 ZNF736 ZSCAN25 MLST8 THOC3 ZNF416 EP300 RBX1 ZNF445	1.99e-03	1022	48	10	MM15436
Pathway	REACTOME_SIGNALING_BY_NOTCH1	CREBBP EP300 RBX1	2.03e-03	74	48	3	M616
Pathway	REACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	CREBBP EP300	2.07e-03	20	48	2	M27881
Pathway	REACTOME_CELLULAR_RESPONSE_TO_HYPOXIA	CREBBP EP300 RBX1	2.11e-03	75	48	3	M641
Pathway	REACTOME_KEAP1_NFE2L2_PATHWAY	MUL1 EP300 RBX1	2.27e-03	77	48	3	MM15698
Pathway	WP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX	CREBBP EP300	2.29e-03	21	48	2	M39593
Pathway	REACTOME_CD209_DC_SIGN_SIGNALING	CREBBP EP300	2.29e-03	21	48	2	M27485
Pathway	WP_EICOSANOID_SYNTHESIS	PNPLA8 ALOX5	2.51e-03	22	48	2	MM15961
Pathway	BIOCARTA_VDR_PATHWAY	CREBBP EP300	2.51e-03	22	48	2	MM1370
Pathway	BIOCARTA_NTHI_PATHWAY	CREBBP EP300	2.51e-03	22	48	2	MM1443
Pathway	REACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA	APP CREBBP EP300	2.72e-03	82	48	3	M1002
Pathway	REACTOME_SIGNALING_BY_NOTCH4	CREBBP EP300 RBX1	2.72e-03	82	48	3	M594
Pathway	BIOCARTA_NTHI_PATHWAY	CREBBP EP300	2.74e-03	23	48	2	M2821
Pathway	REACTOME_HSF1_DEPENDENT_TRANSACTIVATION	MLST8 EP300	2.74e-03	23	48	2	MM14953
Pathway	BIOCARTA_VDR_PATHWAY	CREBBP EP300	2.99e-03	24	48	2	M13404
Pathway	WP_CLEAR_CELL_RENAL_CELL_CARCINOMA_PATHWAYS	MLST8 CREBBP EP300	3.11e-03	86	48	3	M39375
Pathway	KEGG_TGF_BETA_SIGNALING_PATHWAY	CREBBP EP300 RBX1	3.11e-03	86	48	3	M2642
Pathway	REACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	CREBBP EP300	3.24e-03	25	48	2	M27880
Pubmed	Loss of p300 accelerates MDS-associated leukemogenesis.	CREBBP EP300	4.47e-06	2	74	2	27881875
Pubmed	Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.	CREBBP EP300	4.47e-06	2	74	2	34845315
Pubmed	p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.	CREBBP EP300	4.47e-06	2	74	2	19729597
Pubmed	CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.	CREBBP EP300	4.47e-06	2	74	2	39287984
Pubmed	Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.	CREBBP EP300	4.47e-06	2	74	2	20717166
Pubmed	The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.	CREBBP EP300	4.47e-06	2	74	2	25893291
Pubmed	Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.	CREBBP EP300	4.47e-06	2	74	2	11559821
Pubmed	CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.	CREBBP EP300	4.47e-06	2	74	2	32576962
Pubmed	Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.	CREBBP EP300	4.47e-06	2	74	2	19822209
Pubmed	A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.	CREBBP EP300	4.47e-06	2	74	2	24522976
Pubmed	CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.	CREBBP EP300	4.47e-06	2	74	2	21847097
Pubmed	p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.	CREBBP EP300	4.47e-06	2	74	2	34813504
Pubmed	Rubinstein-Taybi Syndrome	CREBBP EP300	4.47e-06	2	74	2	20301699
Pubmed	Potential biomarker of metformin action.	CREBBP EP300	4.47e-06	2	74	2	24639469
Pubmed	The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.	CREBBP EP300	4.47e-06	2	74	2	37816914
Pubmed	Binding of p300/CBP co-activators by polyoma large T antigen.	CREBBP EP300	4.47e-06	2	74	2	11438528
Pubmed	Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.	CREBBP EP300	4.47e-06	2	74	2	10918613
Pubmed	Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.	CREBBP EP300	4.47e-06	2	74	2	35502657
Pubmed	p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.	CREBBP EP300	4.47e-06	2	74	2	31898871
Pubmed	Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.	CREBBP EP300	4.47e-06	2	74	2	30888860
Pubmed	Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.	CREBBP EP300	4.47e-06	2	74	2	27881443
Pubmed	Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.	CREBBP EP300	4.47e-06	2	74	2	19272189
Pubmed	Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.	CREBBP EP300	4.47e-06	2	74	2	32690000
Pubmed	CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.	CREBBP EP300	4.47e-06	2	74	2	30953353
Pubmed	Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.	CREBBP EP300	4.47e-06	2	74	2	21803292
Pubmed	HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.	CREBBP EP300	4.47e-06	2	74	2	9811832
Pubmed	Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.	CREBBP EP300	4.47e-06	2	74	2	24089570
Pubmed	Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.	CREBBP EP300	4.47e-06	2	74	2	15706485
Pubmed	AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.	CREBBP EP300	4.47e-06	2	74	2	39266679
Pubmed	A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.	CREBBP EP300	4.47e-06	2	74	2	22303793
Pubmed	Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.	CREBBP EP300	4.47e-06	2	74	2	34732714
Pubmed	Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.	CREBBP EP300	4.47e-06	2	74	2	34019788
Pubmed	A tetra(ethylene glycol) derivative of benzothiazole aniline enhances Ras-mediated spinogenesis.	RASGRF1 APP	4.47e-06	2	74	2	23719799
Pubmed	Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.	CREBBP EP300	4.47e-06	2	74	2	15860545
Pubmed	Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.	CREBBP EP300	4.47e-06	2	74	2	29460469
Pubmed	Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.	CREBBP EP300	4.47e-06	2	74	2	24551300
Pubmed	Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.	CREBBP EP300	4.47e-06	2	74	2	33911074
Pubmed	The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.	CREBBP EP300	4.47e-06	2	74	2	9018065
Pubmed	Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.	CREBBP EP300	4.47e-06	2	74	2	24648406
Pubmed	CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.	CREBBP EP300	4.47e-06	2	74	2	30135524
Pubmed	Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.	CREBBP EP300	4.47e-06	2	74	2	16596650
Pubmed	The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.	CREBBP EP300	4.47e-06	2	74	2	29217654
Pubmed	Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.	CREBBP EP300	4.47e-06	2	74	2	10049825
Pubmed	CBP/p300 acetyltransferase activity in hematologic malignancies.	CREBBP EP300	4.47e-06	2	74	2	27380996
Pubmed	CREBBP and p300 lysine acetyl transferases in the DNA damage response.	CREBBP EP300	4.47e-06	2	74	2	29170789
Pubmed	Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.	CREBBP EP300	4.47e-06	2	74	2	21555743
Pubmed	CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.	CREBBP EP300	4.47e-06	2	74	2	12646247
Pubmed	Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.	CREBBP EP300	4.47e-06	2	74	2	11867645
Pubmed	Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.	CREBBP EP300	4.47e-06	2	74	2	11963968
Pubmed	Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.	CREBBP EP300	4.47e-06	2	74	2	9528808
Pubmed	Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.	CREBBP EP300	4.47e-06	2	74	2	12696060
Pubmed	CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.	CREBBP EP300	4.47e-06	2	74	2	36109165
Pubmed	Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.	CREBBP EP300	4.47e-06	2	74	2	12242694
Pubmed	CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.	CREBBP EP300	4.47e-06	2	74	2	31182547
Pubmed	Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.	CREBBP EP300	4.47e-06	2	74	2	30635043
Pubmed	Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.	CREBBP EP300	4.47e-06	2	74	2	27648933
Pubmed	Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.	CREBBP EP300	4.47e-06	2	74	2	10610021
Pubmed	Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.	CREBBP EP300	4.47e-06	2	74	2	37314181
Pubmed	Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.	CREBBP EP300	4.47e-06	2	74	2	12397173
Pubmed	CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.	CREBBP EP300	4.47e-06	2	74	2	15641773
Pubmed	Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.	CREBBP EP300	4.47e-06	2	74	2	9733868
Pubmed	Rubinstein-Taybi syndrome in Chinese population with four novel mutations.	CREBBP EP300	4.47e-06	2	74	2	33063428
Pubmed	EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.	CREBBP EP300	4.47e-06	2	74	2	34506759
Pubmed	Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.	CREBBP EP300	4.47e-06	2	74	2	22177454
Pubmed	The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB.	CREBBP EP300	1.34e-05	3	74	2	18070920
Pubmed	Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP.	CREBBP EP300	1.34e-05	3	74	2	27903646
Pubmed	Inhibition of p300/CBP by early B-cell factor.	CREBBP EP300	1.34e-05	3	74	2	12748286
Pubmed	Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.	CREBBP EP300	1.34e-05	3	74	2	24340053
Pubmed	Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response.	CREBBP EP300	1.34e-05	3	74	2	19273602
Pubmed	Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation.	CREBBP EP300	1.34e-05	3	74	2	15649887
Pubmed	DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes.	CREBBP EP300	1.34e-05	3	74	2	26951377
Pubmed	CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.	CREBBP EP300	1.34e-05	3	74	2	21789216
Pubmed	Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex.	CREBBP EP300	1.34e-05	3	74	2	12050117
Pubmed	Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.	CREBBP EP300	1.34e-05	3	74	2	16237459
Pubmed	The IFNgamma-induced STAT1-CBP/P300 association, required for a normal response to the cytokine, is disrupted in Brucella-infected macrophages.	CREBBP EP300	1.34e-05	3	74	2	19041714
Pubmed	Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP.	CREBBP EP300	1.34e-05	3	74	2	12776737
Pubmed	Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation.	CREBBP EP300	1.34e-05	3	74	2	14759370
Pubmed	Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.	CREBBP EP300	1.34e-05	3	74	2	22474372
Pubmed	Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1.	CREBBP EP300	1.34e-05	3	74	2	9488451
Pubmed	Differential roles for the coactivators CBP and p300 on TCF/beta-catenin-mediated survivin gene expression.	CREBBP EP300	1.34e-05	3	74	2	15782138
Pubmed	p300/CREB-binding protein interacts with ATR and is required for the DNA replication checkpoint.	CREBBP EP300	1.34e-05	3	74	2	17272271
Pubmed	Transcriptional activity of interferon regulatory factor (IRF)-3 depends on multiple protein-protein interactions.	CREBBP EP300	1.34e-05	3	74	2	12473110
Pubmed	Transcriptional coactivators CBP and p300 cooperatively enhance HNF-1alpha-mediated expression of the albumin gene in hepatocytes.	CREBBP EP300	1.34e-05	3	74	2	15598887
Pubmed	The acetate/ACSS2 switch regulates HIF-2 stress signaling in the tumor cell microenvironment.	CREBBP EP300	1.34e-05	3	74	2	25689462
Pubmed	Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development.	CREBBP EP300	1.34e-05	3	74	2	16428436
Pubmed	Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators.	CREBBP EP300	1.34e-05	3	74	2	11823864
Pubmed	An essential role for p300/CBP in the cellular response to hypoxia.	CREBBP EP300	1.34e-05	3	74	2	8917528
Pubmed	Histone acetyltransferase p300 is a coactivator for transcription factor REL and is C-terminally truncated in the human diffuse large B-cell lymphoma cell line RC-K8.	CREBBP EP300	1.34e-05	3	74	2	19948376
Pubmed	E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin κ locus.	CREBBP EP300	1.34e-05	3	74	2	22544934
Pubmed	The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300.	CREBBP EP300	1.34e-05	3	74	2	10487758
Pubmed	Two distinct motifs within the p53 transactivation domain bind to the Taz2 domain of p300 and are differentially affected by phosphorylation.	CREBBP EP300	1.34e-05	3	74	2	19166313
Pubmed	Overexpression and ribozyme-mediated targeting of transcriptional coactivators CREB-binding protein and p300 revealed their indispensable roles in adipocyte differentiation through the regulation of peroxisome proliferator-activated receptor gamma.	CREBBP EP300	1.34e-05	3	74	2	11884404
Pubmed	A risk signature of three autophagy-related genes for predicting lower grade glioma survival is associated with tumor immune microenvironment.	CXCR4 MUL1	1.34e-05	3	74	2	33069830
Pubmed	Kaposi's sarcoma-associated herpesvirus-encoded vIRF-3 stimulates the transcriptional activity of cellular IRF-3 and IRF-7.	CREBBP EP300	1.34e-05	3	74	2	14668346
Pubmed	E2A proteins enhance the histone acetyltransferase activity of the transcriptional co-activators CBP and p300.	CREBBP EP300	1.34e-05	3	74	2	22387215
Pubmed	CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity.	CREBBP EP300	1.34e-05	3	74	2	9858599
Pubmed	Transcriptional co-activator p300 maintains basal hepatic gluconeogenesis.	CREBBP EP300	1.34e-05	3	74	2	22815486
Pubmed	Depletion of the transcriptional coactivators CREB-binding protein or EP300 downregulates CD20 in diffuse large B-cell lymphoma cells and impairs the cytotoxic effects of anti-CD20 antibodies.	CREBBP EP300	1.34e-05	3	74	2	31669559
Pubmed	Androgen receptor negatively influences the expression of chemokine receptors (CXCR4, CCR1) and ligand-mediated migration in prostate cancer DU-145.	CXCR4 CCR1	1.34e-05	3	74	2	16969502
Pubmed	Zileuton improves memory deficits, amyloid and tau pathology in a mouse model of Alzheimer's disease with plaques and tangles.	APP ALOX5	1.34e-05	3	74	2	23951061
Interaction	OPA6 interactions	WWP2 EP300 RBX1	8.68e-07	6	72	3	int:OPA6
Interaction	UBE2E2 interactions	WWP2 SRPK1 APP MUL1 TRIM37 RBX1	1.21e-06	96	72	6	int:UBE2E2
Interaction	GSAP interactions	GSAP APP ALOX5	1.51e-06	7	72	3	int:GSAP
Interaction	LYPLA2 interactions	DCAF15 WWP2 CCR1 APP MLST8	1.53e-06	55	72	5	int:LYPLA2
Interaction	ARGFX interactions	MLST8 CREBBP EP300	3.62e-06	9	72	3	int:ARGFX
Interaction	HSF2 interactions	DCAF15 A2ML1 NCBP1 CREBBP EP300	9.28e-06	79	72	5	int:HSF2
Interaction	TP53BP2 interactions	ADAMTS12 WWP2 PRPF19 APP PLEKHN1 CREBBP EP300	2.44e-05	241	72	7	int:TP53BP2
Interaction	HOXB4 interactions	CREBBP EP300 RBX1	5.55e-05	21	72	3	int:HOXB4
Interaction	OR6B3 interactions	SRPK1 APP	7.52e-05	4	72	2	int:OR6B3
Interaction	NR6A1 interactions	CREBBP MUL1 EP300	8.39e-05	24	72	3	int:NR6A1
Interaction	UBE2D1 interactions	TTLL12 WWP2 CREBBP MUL1 TRIM37 EP300 RBX1	8.58e-05	294	72	7	int:UBE2D1
Interaction	ZSCAN20 interactions	ZSCAN18 ZNF202 ZSCAN25 ZNF445	8.60e-05	65	72	4	int:ZSCAN20
Interaction	ALX1 interactions	ZBTB38 CREBBP EP300	9.50e-05	25	72	3	int:ALX1
Interaction	GABPA interactions	A2ML1 APP IGLL5 CREBBP EP300	1.02e-04	130	72	5	int:GABPA
Interaction	ZKSCAN8 interactions	ZSCAN18 ZMYM1 ZSCAN25 APP ZNF445	1.02e-04	130	72	5	int:ZKSCAN8
Interaction	HOXB7 interactions	APP CREBBP EP300	1.07e-04	26	72	3	int:HOXB7
Interaction	MYB interactions	DCAF15 NOP16 CREBBP EP300 RBX1	1.14e-04	133	72	5	int:MYB
Interaction	ALYREF interactions	WWP2 PRPF19 SRPK1 NCBP1 THOC3 TRIM37 EP300 RBX1	1.16e-04	416	72	8	int:ALYREF
Interaction	C16orf78 interactions	SRPK1 APP	1.25e-04	5	72	2	int:C16orf78
Interaction	CSAG1 interactions	SRPK1 APP	1.25e-04	5	72	2	int:CSAG1
Interaction	OCEL1 interactions	SRPK1 APP	1.25e-04	5	72	2	int:OCEL1
Interaction	ALOX5 interactions	OSBPL11 GSAP APP ALOX5	1.43e-04	74	72	4	int:ALOX5
Interaction	HOXD4 interactions	ZSCAN18 CREBBP EP300	1.66e-04	30	72	3	int:HOXD4
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF600 ZBTB38 ZNF155 ZNF256 ZBTB21 ZSCAN18 ZNF202 ZNF74 ZNF736 ZSCAN25 ZNF763 ZNF416 ZNF891 ZNF572 ZNF445	3.89e-09	718	57	15	28
GeneFamily	Oxysterol binding proteins\|Pleckstrin homology domain containing	OSBPL7 OSBPL11	6.32e-04	12	57	2	670
GeneFamily	Dyneins, axonemal	DNAH14 DNAH11	1.29e-03	17	57	2	536
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	CREBBP EP300	1.29e-03	17	57	2	486
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	CREBBP EP300	1.45e-03	18	57	2	91
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASGRF1 OSBPL7 OSBPL11 PLEKHN1	4.04e-03	206	57	4	682
GeneFamily	Ring finger proteins	RNF214 MUL1 TRIM37 RBX1	1.10e-02	275	57	4	58
GeneFamily	Proteases, serine	TMPRSS9 PRSS41	1.69e-02	63	57	2	738
CoexpressionAtlas	Myeloid Cells, MF.Lu, CD11chi CD11b- CD103- MHCII- SiglecF+, Lung, avg-3	RNASE4 TTYH2 CCR1 PNPLA8 GSAP CAV2 APP ALOX5 DNAH11	1.18e-05	425	71	9	GSM538282_500
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TTC28 ZBTB21 OSBPL7 ZNF74 DNAH14	4.52e-06	146	74	5	1bf67a9416f52198931b912a31be4bab09fefd19
ToppCell	droplet-Heart-nan-24m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TLCD3B SPRY4 SLC28A2 CAV2 TRIM37	1.43e-05	185	74	5	11a44006950f6ccade86a85d5f06696d2036ffde
ToppCell	droplet-Heart-nan-24m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TLCD3B SPRY4 SLC28A2 CAV2 TRIM37	1.46e-05	186	74	5	8b316bfed39b91c15d5ae28d9261eb057f113796
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	ZNF155 OSBPL11 IRAG1 CREBBP EP300	1.46e-05	186	74	5	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TTYH2 PNPLA8 GSAP APP ALOX5	1.58e-05	189	74	5	b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TTYH2 PNPLA8 GSAP ALOX5 DNAH11	1.58e-05	189	74	5	f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCell	COVID_vent-Myeloid-Monocytic-Neutrophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	TRPM6 ADGRE3 SRPK1 IRAG1 ALOX5	1.79e-05	194	74	5	eb23b171e429165dd26a64377eae7fa2ce25f547
Disease	Menke-Hennekam syndrome	CREBBP EP300	5.55e-06	2	70	2	cv:C5681632
Disease	Rubinstein-Taybi syndrome (implicated_via_orthology)	CREBBP EP300	5.55e-06	2	70	2	DOID:1933 (implicated_via_orthology)
Disease	Rubinstein-Taybi syndrome	CREBBP EP300	5.55e-06	2	70	2	cv:C0035934
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	5.55e-06	2	70	2	C4551859
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	5.55e-06	2	70	2	180849
Disease	Rubinstein-Taybi syndrome due to CREBBP mutations	CREBBP EP300	5.55e-06	2	70	2	cv:C4551859
Disease	Rubinstein-Taybi syndrome (is_implicated_in)	CREBBP EP300	5.55e-06	2	70	2	DOID:1933 (is_implicated_in)
Disease	Rubinstein-Taybi Syndrome	CREBBP EP300	5.55e-06	2	70	2	C0035934
Disease	p-tau measurement, cerebrospinal fluid biomarker measurement	DDX49 TTC28	5.52e-05	5	70	2	EFO_0004763, EFO_0006794
Disease	Nephrosclerosis	CXCR4 ALOX5	3.01e-04	11	70	2	C0027719
Disease	Eczema	ZBTB38 TTC28 SPRY4 OSBPL7 GSAP	8.58e-04	310	70	5	HP_0000964
Disease	Pancreatic carcinoma	ALOX5 EP300	9.24e-04	19	70	2	C0235974
Disease	p-tau:beta-amyloid 1-42 ratio measurement	DDX49 TTC28	9.24e-04	19	70	2	EFO_0007709
Disease	grip strength measurement	ZBTB38 RASGRF1 WWP2 PKD1 ZBTB21	1.47e-03	350	70	5	EFO_0006941
Disease	Adenocarcinoma of lung (disorder)	TRPM6 CREBBP ALOX5 EP300	1.48e-03	206	70	4	C0152013
Disease	Adenoid Cystic Carcinoma	WNT5B CREBBP EP300	1.75e-03	100	70	3	C0010606
Disease	Drug-Induced Stevens Johnson Syndrome	EP300 RBX1	2.16e-03	29	70	2	C1274933
Disease	Toxic Epidermal Necrolysis	EP300 RBX1	2.16e-03	29	70	2	C0014518
Disease	Mycoplasma-Induced Stevens-Johnson Syndrome	EP300 RBX1	2.16e-03	29	70	2	C3658301
Disease	Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum	EP300 RBX1	2.16e-03	29	70	2	C3658302
Disease	Stevens-Johnson Syndrome	EP300 RBX1	2.31e-03	30	70	2	C0038325

Protein segments in the cluster

Peptide	Gene	Start	Entry
SRQIISHWKNCTRHD	EP300	396	Q09472
HKWISITEALAFFHC	CXCR4	281	P61073
THLHWHTVAKETCSE	APP	146	P05067
LCADDAKTHHWNITA	A2ML1	846	A8K2U0
VAHCASSRQIISHWK	CREBBP	406	Q92793
SSRQIISHWKNCTRH	CREBBP	411	Q92793
SQLRHRWEDTQKHCF	DNAH11	1831	Q96DT5
RHWEKHTCVTFLERT	BMP1	156	P13497
VHHAEKTLSSFCKWQ	ADAMTS12	311	P58397
NHAFHFHCISRWLKT	RBX1	76	P62877
TWRGHHTRSCLKNTE	IQCN	1146	Q9H0B3
AHVDWFTNIRHLACS	ATP23	136	Q9Y6H3
NTTCVDRFINWFSHH	NCBP1	406	Q09161
ASCRHDWHQTDSLVV	ITGB1BP2	216	Q9UKP3
ASLWHHCEHRETYQK	IRAG1	576	Q9Y6F6
DHTVRFWQAHSGICT	MLST8	21	Q9BVC4
TTHLWNDCSKIIHQR	MUL1	106	Q969V5
SRRWVLSAAHCFQKH	PRSS41	86	Q7RTY9
ICKQWTEILHFTEHS	PRPF19	461	Q9UMS4
CHIVETNWRKHNLHS	GSAP	646	A4D1B5
WVLTAAHCTDIKTRH	HABP2	356	Q14520
QWKSHRSYSCQVTHE	IGLL5	186	B9A064
FSKTQWEFTHHTCSL	CCR1	171	P32246
QVVSAHTAKHCKEFW	DNAH14	321	Q0VDD8
HTAKHCKEFWVITAS	DNAH14	326	Q0VDD8
HEDWSIIIFTNTCKT	DDX49	246	Q9Y6V7
VFCRNTCHDLKHFWE	FAM240A	16	A0A1B0GVK7
VTTHSFDKVWICSHA	CAV2	61	P51636
EVIRHDATWGHQFCS	DCAF15	456	Q66K64
ALTTKVHFECTGWHD	PKD1	2486	P98161
WVSRLQICTQHHTEA	OSBPL11	146	Q9BXB4
HFEWNKVTSCIHNVL	OSBPL7	631	Q9BZF2
HSHSCHIKTWVTLFI	MROH5	1246	Q6ZUA9
HTNIIRCKWTKSEAH	PNPLA8	51	Q9NP80
WKNIHERVCSLLTSH	SPATA6L	341	Q8N4H0
CDQDVTHHWISFSGR	SPRY4	81	Q9C004
ENHHEKLSVFCWTCK	TRIM37	96	O94972
DHLWDETLSSSHQKC	PLEKHN1	581	Q494U1
AKIWVRSSDFHVHQT	ALOX5	351	P09917
IFSRHCTKEDYQTWH	SORCS3	691	Q9UPU3
CKALRTNEWLAHHSR	SSMEM1	201	Q8WWF3
TDTSAKWRLSHCTVH	NEPRO	481	Q6NW34
ACWVHKHFTEDIQTR	SRPK1	501	Q96SB4
CSHIRHAWDHAKSVR	NOP16	36	Q9Y3C1
NVLRHWVSKHSQDFE	RASGRF1	956	Q13972
LSAHREVAQFCFTHW	SLC23A3	206	Q6PIS1
ILFACSKHHSAVSWR	SLC28A2	186	O43868
WSRDGCFLIHVNKSH	ADGRE3	316	Q9BY15
ECWKSFSNSSHLRTH	ZNF572	136	Q7Z3I7
ECWKTFSQSSTLVIH	ZNF572	416	Q7Z3I7
HCKRFNTFIHEDIWN	RNASE4	66	P34096
THVLHKECIKFWAQT	RNF214	676	Q8ND24
HKRFHTNFKVWTHCQ	ZBTB21	581	Q9ULJ3
TAQSHLDLKVWSCHT	WWP2	76	O00308
VRTWHKIFQESTVLH	TRPM6	1811	Q9BX84
TKQHHSCCITWTAVV	TTYH2	81	Q9BSA4
SECWKTFSQRHHLEV	ZSCAN25	406	Q6NSZ9
ECWKSFSNHSSLVKH	ZNF256	551	Q9Y2P7
FLAHSAKVHSVAWSC	THOC3	51	Q96J01
SRTCDYKHHWQDVLV	PLPP5	201	Q8NEB5
DRWLLSAAHCFNHTK	TMPRSS9	536	Q7Z410
FKSVQVERCHCKFHW	WNT5B	326	Q9H1J7
SIFLIDHAWTCRVEH	TTLL12	116	Q14166
ECVHFATHISWKLSA	TTC28	1541	Q96AY4
AFRWSSNCARHEKIH	ZNF445	521	P59923
KWSQCRRESSHKHTF	ZNF416	216	Q9BWM5
CWKTFHFSLALAEHQ	ZSCAN18	446	Q8TBC5
TSCKHIIDDQHWLSS	TLCD3B	61	Q71RH2
FRWSSCLLNHQRVHS	ZNF155	381	Q12901
WKAFSCHSSLIVHQR	ZNF74	506	Q16587
KKHISQSCWTVHDRT	ZMYM1	801	Q5SVZ6
IFWSHTICISSHVLE	ZBTB38	61	Q8NAP3
KSFSWCHSFQIHERT	ZNF763	291	Q0D2J5
CDKAFAWNSHLVRHT	ZNF600	391	Q6ZNG1
CGKHFRWTSDLVRHQ	ZNF202	486	O95125
ESHECDTTLWHFQRN	ZNF891	246	A8MT65
ECGKASSWFSHLIRH	ZNF736	401	B4DX44