Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH2 DNAH7 DNAH1 SPTBN5

3.14e-04371774GO:0045505
GeneOntologyMolecularFunctionATP-dependent activity

IPO8 TOR2A MYO10 SMCHD1 DNAH2 RNF213 IDE ATP9A DDX55 DNAH7 ABCA7 DNAH1 DDX53 DDX43 ATP2B4

3.88e-0461417715GO:0140657
GeneOntologyMolecularFunctionanandamide 8,9 epoxidase activity

CYP2D7 CYP2D6

4.63e-0441772GO:0062187
GeneOntologyMolecularFunctionanandamide 11,12 epoxidase activity

CYP2D7 CYP2D6

4.63e-0441772GO:0062188
GeneOntologyMolecularFunctionsteroid 21-monooxygenase activity

CYP2D7 CYP2D6

4.63e-0441772GO:0004509
GeneOntologyMolecularFunctionprogesterone 21-hydroxylase activity

CYP2D7 CYP2D6

4.63e-0441772GO:0106309
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH2 DNAH7 DNAH1

5.07e-04181773GO:0008569
GeneOntologyMolecularFunctionATP hydrolysis activity

TOR2A SMCHD1 DNAH2 RNF213 IDE ATP9A DDX55 DNAH7 ABCA7 DDX53 DDX43 ATP2B4

5.89e-0444117712GO:0016887
GeneOntologyMolecularFunctionsmall GTPase binding

GAPVD1 IPO8 IPO4 RIN1 LLGL1 XPO5 RIMS4 DAAM2 PKN1 SORL1

6.05e-0432117710GO:0031267
GeneOntologyMolecularFunction[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity

PPM1M PDP2

7.68e-0451772GO:0004741
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

PCDH11Y CDH23 CNTN6 CELSR1 FAT2 HMCN2 NECTIN2 ROBO2 ROBO3 CDH2

4.40e-0618717410GO:0007156
GeneOntologyCellularComponentinner dynein arm

DNAH2 DNAH7 DNAH1

6.63e-05101753GO:0036156
DomainFN3_dom

PAPPA2 IL13RA1 TSPOAP1 OBSCN CNTN6 IGDCC4 ROBO2 FLRT2 ROBO3 TNXB SORL1

4.84e-0620917611IPR003961
DomainEGF-like_CS

FBLN7 MATN3 LAMA3 VWDE CELSR1 FAT2 HMCN2 NCAN LRP6 ADAM17 TNXB SORL1

7.13e-0626117612IPR013032
DomainFN3

PAPPA2 TSPOAP1 OBSCN CNTN6 IGDCC4 ROBO2 FLRT2 ROBO3 TNXB SORL1

1.04e-0518517610SM00060
DomainFN3

IL13RA1 TSPOAP1 OBSCN CNTN6 IGDCC4 ROBO2 FLRT2 ROBO3 TNXB SORL1

1.97e-0519917610PS50853
Domainfn3

TSPOAP1 OBSCN CNTN6 IGDCC4 ROBO2 FLRT2 ROBO3 TNXB SORL1

2.35e-051621769PF00041
DomainEGF-like_dom

FBLN7 MATN3 LAMA3 VWDE CELSR1 FAT2 HMCN2 NCAN LRP6 TNXB SORL1

2.51e-0524917611IPR000742
DomainEGF_2

FBLN7 MATN3 LAMA3 VWDE CELSR1 FAT2 HMCN2 NCAN LRP6 TNXB SORL1

4.43e-0526517611PS01186
DomainPH

PHLDB3 CNKSR1 CDC42BPA PLEKHG4 MYO10 TBC1D2B OBSCN SPTBN5 SBF1 AGAP3

6.49e-0522917610PF00169
DomainEGF

FBLN7 MATN3 LAMA3 VWDE CELSR1 FAT2 NCAN LRP6 TNXB SORL1

8.05e-0523517610SM00181
DomainEGF_3

FBLN7 MATN3 VWDE CELSR1 FAT2 HMCN2 NCAN LRP6 TNXB SORL1

8.05e-0523517610PS50026
DomainEGF

FBLN7 MATN3 CELSR1 FAT2 NCAN LRP6 TNXB

1.93e-041261767PF00008
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH7 DNAH1

2.77e-04141763IPR024317
DomainDynein_HC_stalk

DNAH2 DNAH7 DNAH1

2.77e-04141763IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH7 DNAH1

2.77e-04141763IPR013602
DomainDHC_N2

DNAH2 DNAH7 DNAH1

2.77e-04141763PF08393
DomainMT

DNAH2 DNAH7 DNAH1

2.77e-04141763PF12777
DomainAAA_8

DNAH2 DNAH7 DNAH1

2.77e-04141763PF12780
DomainPH

PHLDB3 CNKSR1 CDC42BPA PLEKHG4 MYO10 TBC1D2B OBSCN SPTBN5 SBF1 AGAP3

3.15e-0427817610SM00233
DomainPH_DOMAIN

PHLDB3 CNKSR1 CDC42BPA PLEKHG4 MYO10 TBC1D2B OBSCN SPTBN5 SBF1 AGAP3

3.24e-0427917610PS50003
DomainPH_domain

PHLDB3 CNKSR1 CDC42BPA PLEKHG4 MYO10 TBC1D2B OBSCN SPTBN5 SBF1 AGAP3

3.33e-0428017610IPR001849
DomainDHC_fam

DNAH2 DNAH7 DNAH1

3.44e-04151763IPR026983
DomainDynein_heavy

DNAH2 DNAH7 DNAH1

3.44e-04151763PF03028
DomainDynein_heavy_dom

DNAH2 DNAH7 DNAH1

3.44e-04151763IPR004273
Domain-

PHLDB3 CNKSR1 CDC42BPA PLEKHG4 MYO10 TBC1D2B OBSCN SPTBN5 PTPN4 SBF1 ENAH AGAP3

3.46e-04391176122.30.29.30
DomainIg-like_fold

PAPPA2 IL13RA1 TSPOAP1 OBSCN CNTN6 IGDCC4 IGSF10 TGM1 HMCN2 NCAN NECTIN2 ROBO2 FLRT2 FGFR4 ROBO3 TNXB SORL1

3.79e-0470617617IPR013783
DomainIBN_N

IPO8 IPO4 XPO5

4.21e-04161763SM00913
DomainIg_I-set

OBSCN CNTN6 IGDCC4 IGSF10 HMCN2 ROBO2 FGFR4 ROBO3

4.49e-041901768IPR013098
DomainI-set

OBSCN CNTN6 IGDCC4 IGSF10 HMCN2 ROBO2 FGFR4 ROBO3

4.49e-041901768PF07679
DomainImportin-beta_N

IPO8 IPO4 XPO5

5.08e-04171763IPR001494
DomainCH

CFAP47 SPTB SPTBN5 MAPRE1 UTRN

5.18e-04701765PF00307
DomainLys_sp_deMease-like_dom

KDM5C KDM5D

5.23e-0441762IPR013637
DomainPLU-1

KDM5C KDM5D

5.23e-0441762PF08429
Domain-

PAPPA2 IL13RA1 TSPOAP1 OBSCN CNTN6 IGDCC4 IGSF10 TGM1 NCAN NECTIN2 ROBO2 FLRT2 FGFR4 ROBO3 TNXB SORL1

5.51e-04663176162.60.40.10
Domain-

CFAP47 SPTB SPTBN5 MAPRE1 UTRN

5.53e-047117651.10.418.10
DomainCH

CFAP47 SPTB SPTBN5 MAPRE1 UTRN

6.28e-04731765PS50021
DomainCH-domain

CFAP47 SPTB SPTBN5 MAPRE1 UTRN

7.11e-04751765IPR001715
DomainEGF_1

FBLN7 LAMA3 VWDE CELSR1 FAT2 HMCN2 NCAN LRP6 TNXB

7.19e-042551769PS00022
DomainPH_dom-like

PHLDB3 CNKSR1 CDC42BPA PLEKHG4 MYO10 TBC1D2B OBSCN SPTBN5 PTPN4 SBF1 ENAH AGAP3

7.39e-0442617612IPR011993
Domainzf-C5HC2

KDM5C KDM5D

8.67e-0451762PF02928
DomainZnf_C5HC2

KDM5C KDM5D

8.67e-0451762IPR004198
DomainEGF_CA

FBLN7 MATN3 CELSR1 FAT2 HMCN2 NCAN

1.05e-031221766SM00179
DomainVWFA

MATN3 COL22A1 ITIH1 ITIH4 HMCN2

1.07e-03821765PS50234
DomainEGF-like_Ca-bd_dom

FBLN7 MATN3 CELSR1 FAT2 HMCN2 NCAN

1.15e-031241766IPR001881
DomainVWA

MATN3 COL22A1 ITIH1 ITIH4 HMCN2

1.19e-03841765SM00327
DomainSpectrin

SPTB SPTBN5 UTRN

1.27e-03231763PF00435
DomainACTININ_2

SPTB SPTBN5 UTRN

1.27e-03231763PS00020
DomainACTININ_1

SPTB SPTBN5 UTRN

1.27e-03231763PS00019
DomainActinin_actin-bd_CS

SPTB SPTBN5 UTRN

1.27e-03231763IPR001589
DomainITI_HC_C

ITIH1 ITIH4

1.29e-0361762IPR010600
DomainITI_HC_C

ITIH1 ITIH4

1.29e-0361762PF06668
DomainIGc2

OBSCN CNTN6 IGDCC4 IGSF10 HMCN2 ROBO2 FGFR4 ROBO3

1.77e-032351768SM00408
DomainIg_sub2

OBSCN CNTN6 IGDCC4 IGSF10 HMCN2 ROBO2 FGFR4 ROBO3

1.77e-032351768IPR003598
DomainVWA

MATN3 COL22A1 ITIH1 ITIH4

1.91e-03561764PF00092
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

COG2 IL13RA1 NR2C2 PLEKHG4 SMCHD1 RDH14 RNF213 APOB TTYH3 SLC30A1 MAPRE1 FANCG INTS5 AGO3 XPO5 NECTIN2 RBM5 RHBDD3 PKN1 ADAM17 ATP2B4 BAG6 CEP170B

6.19e-0910611782333845483
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

GPHN PHLDB3 GAPVD1 IPO8 OFD1 RPAP3 CDH23 IPO4 CBS HDAC7 CDR2L MAPRE1 RIN1 NEK1 DZANK1 GLB1 XPO5 NECTIN2 ENAH C3 SNRPD1 BBS12 EXOC4 SORL1 AGAP3

1.89e-0813211782527173435
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

LRRC57 CDC42BPA IPO8 NELFA RFFL TTYH3 ADD3 TMCO4 STK10 RIN1 LLGL1 XPO5 ERI3 NECTIN2 ADAM17 CDH2 UTRN ATP2B4

3.67e-087191781835337019
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PHLDB3 CDC42BPA OFD1 MYO10 OBSCN PFAS SMG5 TTYH3 REV3L ABCA7 HDAC7 CDR2L STK10 CELSR1 INTS5 SBF1 PCNX1 PKN1 SNAPC4 CEP170B AGAP3

2.67e-0711051782135748872
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

PHLDB3 SLC30A1 ADD3 STK10 LLGL1 GLB1 SBF1 NECTIN2 ROBO2 CDH2 UTRN ATP2B4 EXOC4

3.03e-074211781336976175
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

GPHN CNKSR1 NELFA KDM5C IPO4 SF1 STK10 RIN1 ENAH GMEB1 PKN1 BAG6 EXOC4 AGAP3

3.67e-075031781416964243
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

LRRC57 CDC42BPA SLC30A1 ADD3 STK10 LLGL1 NECTIN2 DAAM2 FLRT2 UTRN ATP2B4 AGAP3

6.37e-073771781238117590
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MBLAC2 CDC42BPA ACTR3C SPTB PCDH11Y OBSCN LAMA3 RNF213 TTYH3 IDE DNAH1 TMCO4 STK10 PTPN4 ERI3 NECTIN2 ENAH RBM5 PKN1 ARHGEF37 UTRN CEP170B EXOC4 AGAP3

6.94e-0714891782428611215
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CDC42BPA OFD1 RPAP3 PPM1M RNF213 PFAS IDE SLC30A1 PTPN4 SBF1 SUN2 NECTIN2 ENAH LRP6 PDP2 MAPK1 SNRPD1 UTRN ATP2B4

2.08e-0610491781927880917
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

GAPVD1 CDC42BPA RNF213 APOB IPO4 SLC30A1 DNAH7 ADD3 MAPRE1 BRCA1 NECTIN2 RBM5 RHBDD3 PKN1 FLRT2 AGAP3

2.79e-067771781635844135
Pubmed

Structure and mapping of the mouse matrilin-3 gene (Matn3), a member of a gene family containing a U12-type AT-AC intron.

MATN3 APOB ADAM17

4.54e-067178310656920
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

GAPVD1 DNAH2 RDH14 IPO4 ATP9A INTS5 GLB1 XPO5 NECTIN2 LRP6 RHBDD3 MAPK1 SLC30A9 HEATR5B ATP2B4 BAG6 EXOC4

7.73e-069421781731073040
Pubmed

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.

CYP2D6 APOB GABBR2 CBS IKBKE NECTIN2 PTCH2 ADAM17 FGFR4 CDH2

8.84e-063311781020634891
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

GPHN GAPVD1 CDC42BPA OFD1 DNAH7 HDAC7 CDR2L NEK1 SBF1 IKBKE TET1 NECTIN2 UTRN CEP170B EXOC4 AGAP3

1.01e-058611781636931259
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

GPHN IPO4 GABBR2 TMEM132B ITIH1 ITIH4 DZANK1 CCDC124 AGO3 SBF1 NCAN ENAH PKN1 MAPK1 CDH2 ATP2B4 CEP170B

1.03e-059631781728671696
Pubmed

Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.

PAPPA2 GABRG2 PEG3 LAMA3 C3 FLRT2

1.18e-0598178619834535
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

GAPVD1 OFD1 PFAS ADD3 NEK1 CCDC124 UTRN CEP170B

1.32e-05209178836779422
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

OBSCN RNF213 DDX55 IGDCC4 AGO3 ROBO2

1.40e-05101178610997877
Pubmed

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.

PPM1M DPP3 ITIH1 ITIH4 DNAH1 RIN1

1.48e-05102178621926972
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

ATP9A GABBR2 ITIH1 ADD3 DZANK1 LLGL1 SBF1 NCAN CDH2 CEP170B AGAP3

1.49e-054301781132581705
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

GAPVD1 CDC42BPA KDM5C SMCHD1 TBC1D2B SMG5 DDX55 INTS5 SBF1 TET1 ROBO2 PCNX1

2.00e-055291781214621295
Pubmed

Dlg-1 Interacts With and Regulates the Activities of Fibroblast Growth Factor Receptors and EphA2 in the Mouse Lens.

FGFR4 MAPK1 CDH2

2.11e-0511178326906157
Pubmed

Glycinergic and GABAergic synaptic transmission are differentially affected by gephyrin in spinal neurons.

GPHN GABRG2

2.60e-052178215963957
Pubmed

Essential role of obscurin kinase-1 in cardiomyocyte coupling via N-cadherin phosphorylation.

OBSCN CDH2

2.60e-052178238127465
Pubmed

Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism?

CYP2D7 CYP2D6

2.60e-052178211207030
Pubmed

Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.

KDM5C KDM5D

2.60e-052178232081420
Pubmed

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism.

CYP2D7 CYP2D6

2.60e-05217823123997
Pubmed

ERK2 Phosphorylates PFAS to Mediate Posttranslational Control of De Novo Purine Synthesis.

PFAS MAPK1

2.60e-052178232485148
Pubmed

Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells.

MAP3K1 STK10

2.60e-052178211903060
Pubmed

A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.

KDM5C KDM5D

2.60e-05217827524912
Pubmed

Molecular and structural bases of interaction between extracellular domains of nectin-2 and N-cadherin.

NECTIN2 CDH2

2.60e-052178230183103
Pubmed

Lysine demethylase 5C epigenetically reduces transcription of ITIH1 that results in augmented progression of liver hepatocellular carcinoma.

KDM5C ITIH1

2.60e-052178235080113
Pubmed

The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection.

CYP2D7 CYP2D6

2.60e-052178219594327
Pubmed

Coding-noncoding gene expression in intrahepatic cholangiocarcinoma.

CYP2D7 CYP2D6

2.60e-052178226297049
Pubmed

Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

KDM5C KDM5D

2.60e-05217829060413
Pubmed

Novel progressive acrodysostosis-like skeletal dysplasia, cerebellar atrophy, and ichthyosis.

FBLN7 PPM1M

2.60e-052178232783359
Pubmed

A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine.

CYP2D7 CYP2D6

2.60e-052178215051713
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5C KDM5D

2.60e-052178210441747
Pubmed

Molecular evolution of the CYP2D subfamily in primates: purifying selection on substrate recognition sites without the frequent or long-tract gene conversion.

CYP2D7 CYP2D6

2.60e-052178225808902
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5C KDM5D

2.60e-052178216416087
Pubmed

Reactive oxygen species and p38 mitogen-activated protein kinase mediate tumor necrosis factor α-converting enzyme (TACE/ADAM-17) activation in primary human monocytes.

ADAM17 MAPK1

2.60e-052178221865167
Pubmed

The FGFR4-388arg Variant Promotes Lung Cancer Progression by N-Cadherin Induction.

FGFR4 CDH2

2.60e-052178229402970
Pubmed

Characterization of Cyp2d22, a novel cytochrome P450 expressed in mouse mammary cells.

CYP2D7 CYP2D6

2.60e-052178211032406
Pubmed

Myosin X regulates neuronal radial migration through interacting with N-cadherin.

MYO10 CDH2

2.60e-052178226347613
Pubmed

Shared cell adhesion molecule (CAM) homology domains point to CAMs signalling via FGF receptors.

FGFR4 CDH2

2.60e-05217829168198
Pubmed

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.

PHLDB3 GAPVD1 MBLAC2 RPAP3 RDH14 TTYH3 IDE CBS PTPN4 GLB1 SBF1 XPO5 MAPK1 UTRN BAG6 EXOC4

2.62e-059311781627432908
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

CDC42BPA DEPDC4 IPO8 TSPOAP1 SMCHD1 PARP3 RNF213 ATP9A DPH5 UTRN TNXB ATP2B4

3.03e-055521781210737800
Pubmed

Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.

KDM5C PCDH11Y KDM5D

3.63e-0513178314660691
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

GPHN GAPVD1 IPO8 SMCHD1 BSPRY PFAS IDE IPO4 PTPN4 SBF1 XPO5 C3 MAPK1 UTRN BAG6 SORL1

4.48e-059741781628675297
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

RNF213 CCDC124 AGO3 ENAH UTRN

4.57e-0576178527542412
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH2 DNAH7 DNAH1

4.60e-051417839373155
Pubmed

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.

IPO8 RNF213 IPO4 GSDME XPO5 SNRPD1 EXOC4

4.66e-05183178723956138
Pubmed

LZTR1 is a regulator of RAS ubiquitination and signaling.

SLC30A1 ADD3 LLGL1 SBF1 NECTIN2 ATP2B4

5.12e-05127178630442766
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

LRRC57 TOR2A CHDH SPTB NDST2 OBSCN CNTN6 ADD3 SUN2 NCAN NECTIN2 RBM5 ADAM17 ROBO3 SNRPD1 CDH2 UTRN CEP170B

5.65e-0512151781815146197
Pubmed

Genetic susceptibility to distinct bladder cancer subphenotypes.

CYP2D6 CALCR PARP3 APOB SLC30A1 CBS ABCA7 TGM1 BRCA1 LRP6

6.80e-054211781019692168
Pubmed

Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme.

MYO10 MAPK1 CDH2

7.03e-0516178320439720
Pubmed

Human inter-alpha-trypsin inhibitor heavy chain H3 gene. Genomic organization, promoter analysis, and gene linkage.

ITIH1 ITIH4

7.79e-05317829756925
Pubmed

Quantitative trait loci analysis for the differences in susceptibility to atherosclerosis and diabetes between inbred mouse strains C57BL/6J and C57BLKS/J.

APOB ADAM17

7.79e-053178210393218
Pubmed

Constitutive androstane receptor activation decreases plasma apolipoprotein B-containing lipoproteins and atherosclerosis in low-density lipoprotein receptor-deficient mice.

APOB NR1I3

7.79e-053178221778422
Pubmed

Alternative splicing of the Robo3 axon guidance receptor governs the midline switch from attraction to repulsion.

ROBO2 ROBO3

7.79e-053178218466743
Pubmed

Imaging of Rab5 activity identifies essential regulators for phagosome maturation.

GAPVD1 MAPRE1

7.79e-053178218385674
Pubmed

Mutation in EGFP domain of LDL receptor-related protein 6 impairs cellular LDL clearance.

APOB LRP6

7.79e-053178218948618
Pubmed

Induced proliferation of human MRC-5 cells by nitrogen oxides via direct and indirect activation of MEKK1, JNK, and p38 signals.

MAP3K1 MAPK1

7.79e-053178212079429
Pubmed

Contribution to Alzheimer's disease risk of rare variants in TREM2, SORL1, and ABCA7 in 1779 cases and 1273 controls.

ABCA7 SORL1

7.79e-053178228789839
Pubmed

The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene.

CYP2D7 CYP2D6

7.79e-05317822574001
Pubmed

Impaired tamoxifen metabolism reduces survival in familial breast cancer patients.

CYP2D6 BRCA1

7.79e-053178218794105
Pubmed

Gamma-irradiation-induced DNA damage checkpoint activation involves feedback regulation between extracellular signal-regulated kinase 1/2 and BRCA1.

BRCA1 MAPK1

7.79e-053178218593910
Pubmed

Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo.

CALCR MAPK1

7.79e-053178214970190
Pubmed

Identification of a mouse male-specific transplantation antigen, H-Y.

KDM5C KDM5D

7.79e-05317827544442
Pubmed

Active ERK1/2 protein interacts with the phosphorylated nuclear constitutive active/androstane receptor (CAR; NR1I3), repressing dephosphorylation and sequestering CAR in the cytoplasm.

MAPK1 NR1I3

7.79e-053178221873423
Pubmed

Peptide-based mediated disruption of N-cadherin-LRP5/6 interaction promotes Wnt signaling and bone formation.

LRP6 CDH2

7.79e-053178222576936
Pubmed

Identification of the primary gene defect at the cytochrome P450 CYP2D locus.

CYP2D7 CYP2D6

7.79e-05317821978251
Pubmed

Robo family of proteins exhibit differential expression in mouse spinal cord and Robo-Slit interaction is required for midline crossing in vertebrate spinal cord.

ROBO2 ROBO3

7.79e-053178215768400
Pubmed

Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system.

GPHN ENAH

7.79e-053178212967995
Pubmed

Rig-1 a new member of Robo family genes exhibits distinct pattern of expression during mouse development.

ROBO2 ROBO3

7.79e-053178214678835
Pubmed

FGFR1 and FGFR4 oncogenicity depends on n-cadherin and their co-expression may predict FGFR-targeted therapy efficacy.

FGFR4 CDH2

7.79e-053178232114392
Pubmed

Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux.

PCDH11Y ROBO2

7.79e-053178217357069
Pubmed

Comparative assignments of the genes of the inter-alpha-inhibitor family in human and mouse: ITIH4 is close to ITIH1 and ITIH3, on HSA 3 and MMU 14.

ITIH1 ITIH4

7.79e-05317829126497
Pubmed

Recently reported familial hypercholesterolemia-related mutations from cases in the Middle East and North Africa region.

APOB SORL1

7.79e-053178230694837
Pubmed

N-cadherin restrains PTH activation of Lrp6/β-catenin signaling and osteoanabolic action.

LRP6 CDH2

7.79e-053178225088803
Pubmed

Livin promotes the progression and metastasis of breast cancer through the regulation of epithelial‑mesenchymal transition via the p38/GSK3β pathway.

BIRC7 MAPK1

7.79e-053178229039608
Pubmed

Extracellular signal-regulated kinase is an endogenous signal retaining the nuclear constitutive active/androstane receptor (CAR) in the cytoplasm of mouse primary hepatocytes.

MAPK1 NR1I3

7.79e-053178217314319
Pubmed

Association between mitogen-activated protein kinase kinase kinase 1 rs889312 polymorphism and breast cancer risk: evidence from 59,977 subjects.

MAP3K1 BRCA1

7.79e-053178220809358
Pubmed

NIMA-related kinase 1 (NEK1) regulates meiosis I spindle assembly by altering the balance between α-Adducin and Myosin X.

MYO10 NEK1

7.79e-053178228982183
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

NR2C2 CDC42BPA IPO8 OFD1 RPAP3 BAG1 PFAS IPO4 SLC30A1 ADD3 MAPRE1 LLGL1 GLB1 SBF1 SUN2 NECTIN2 SLC30A9 ATP2B4 BAG6 EXOC4

8.17e-0514871782033957083
Pubmed

Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.

APOB ITIH1 ITIH4 C3

9.96e-0547178414760718
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CFAP47 GAPVD1 OBSCN DNAH2 RNF213 SYNC REV3L PARP14 TMEM132B SF1 TMCO4 IGSF10 UTRN

1.16e-047361781329676528
Pubmed

TRIM65 regulates microRNA activity by ubiquitination of TNRC6.

PFAS IDE CCDC124 AGO3 GLB1 PRR14L MAPK1 BAG6 SORL1

1.17e-04364178924778252
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

TBC1D2B OBSCN RNF213 SPTBN5 RIN1 PKN1 AGAP3

1.24e-04214178722199357
Pubmed

PTEN identified as important risk factor of chronic obstructive pulmonary disease.

CYP2D6 CALCR APOB SLC30A1 CBS ABCA7 TGM1 BRCA1 LRP6

1.43e-04374178919625176
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

GPHN GABRG2 ACTR3C SPTB ATP9A ADD3 RIN1 TGM1 DZANK1 SBF1 NCAN MAPK1 SNRPD1 CDH2 UTRN ATP2B4 CEP170B EXOC4 AGAP3

1.47e-0414311781937142655
Pubmed

Evidence for the existence of two Robo3 isoforms with divergent biochemical properties.

ROBO2 ROBO3

1.55e-044178216226035
Pubmed

Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence.

MAP3K1 MAPK1

1.55e-044178211971971
Pubmed

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

KDM5C KDM5D

1.55e-044178217320160
Pubmed

ADAM17/EGFR axis promotes transglutaminase-dependent skin barrier formation through phospholipase C γ1 and protein kinase C pathways.

TGM1 ADAM17

1.55e-044178228004780
Pubmed

Hetero-oligomerization between GABAA and GABAB receptors regulates GABAB receptor trafficking.

GABRG2 GABBR2

1.55e-044178214966130
Pubmed

A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.

KDM5C KDM5D

1.55e-04417827951230
Pubmed

Interactions of drebrin and gephyrin with profilin.

GPHN ENAH

1.55e-04417829473484
Pubmed

Multiple roles for slits in the control of cell migration in the rostral migratory stream.

ROBO2 ROBO3

1.55e-044178214960623
Pubmed

MEK-ERK inhibition corrects the defect in VLDL assembly in HepG2 cells: potential role of ERK in VLDL-ApoB100 particle assembly.

APOB MAPK1

1.55e-044178217038630
Cytoband2p24-p23

MATN3 APOB

1.49e-05217822p24-p23
Cytoband3p21.1

CHDH ITIH1 ITIH4 DNAH1

2.18e-054217843p21.1
CytobandEnsembl 112 genes in cytogenetic band chr3p21

CHDH PARP3 PPM1M ITIH1 ITIH4 DNAH1 RBM5

2.50e-043161787chr3p21
GeneFamilyFibronectin type III domain containing

TSPOAP1 OBSCN CNTN6 IGDCC4 ROBO2 FLRT2 ROBO3 TNXB SORL1

1.69e-061601259555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

OBSCN CNTN6 IGDCC4 IGSF10 HMCN2 ROBO2 FGFR4 ROBO3

1.62e-051611258593
GeneFamilyDyneins, axonemal

DNAH2 DNAH7 DNAH1

2.04e-04171253536
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PHLDB3 CNKSR1 PLEKHG4 MYO10 SPTB SBF1 AGAP3

5.77e-042061257682
GeneFamilyBCL2 associated athanogene family

BAG1 BAG6

6.98e-04612521139
GeneFamilyEF-hand domain containing|Spectrins

SPTB SPTBN5

9.73e-04712521113
GeneFamilyFibulins

FBLN7 HMCN2

1.29e-0381252556
GeneFamilyCytochrome P450 family 2

CYP2D7 CYP2D6 CYP2W1

1.80e-033512531001
GeneFamilyVPS9 domain containing

GAPVD1 RIN1

2.06e-03101252928
GeneFamilyDEAD-box helicases

DDX55 DDX53 DDX43

3.04e-03421253499
CoexpressionDEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN

TSPOAP1 MYO10 KDM5C BAG1 TBC1D2B PFAS GLB1 BRCA1 SBF1 ADAM17 SORL1

3.18e-0627617811M3063
CoexpressionGSE24574_NAIVE_VS_TCONV_CD4_TCELL_UP

CYP2D6 APOB ITIH4 ADD3 SUN2 PCNX1 CDH2 UTRN SORL1

9.71e-062001789M8328
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SMCHD1 KDM5D SF1 N4BP2L2 PCNX1 UTRN EXOC4

4.10e-061621787b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ZFAT TSPOAP1 BSPRY PEG3 CYP2W1 ZSCAN32 CELSR1

9.78e-061851787636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYO10 MATN3 TBC1D2B OBSCN DAAM2 FGFR4 UTRN

1.01e-051861787888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCRG1 TTYH3 CBS IGDCC4 CELSR1 NCAN KCNN3

1.20e-051911787fd345837bfc40d85256b9a7e4fd3343bcbfe0ae5
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

TSPOAP1 RNF213 STK10 PTPN4 PCNX1 UTRN ATP2B4

1.38e-0519517879990440bda7fac5d00ef80444fab07459be625e1
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_4|COVID-19_Mild / Disease condition and Cell class

SMCHD1 RNF213 TTYH3 PARP14 MAP3K1 NECTIN2 ADAM17

1.42e-0519617873729d1444c65cad640377894decc64129bc3fd5b
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TSPOAP1 RNF213 STK10 PTPN4 PCNX1 UTRN ATP2B4

1.42e-051961787418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TSPOAP1 RNF213 STK10 PTPN4 PCNX1 UTRN ATP2B4

1.42e-051961787581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TSPOAP1 RNF213 STK10 PTPN4 PCNX1 UTRN ATP2B4

1.42e-0519617876beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TSPOAP1 RNF213 STK10 PTPN4 PCNX1 UTRN ATP2B4

1.42e-051961787c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCellhealthy_donor-Lymphocytic-ILC-NK_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

TSPOAP1 RNF213 STK10 PTPN4 UTRN ATP2B4 SORL1

1.52e-051981787d7053a898e04478c577381085f615edaad3cdc5b
ToppCellhealthy_donor-Lymphocytic-ILC|healthy_donor / Disease condition, Lineage, Cell class and subclass

TSPOAP1 RNF213 STK10 PTPN4 UTRN ATP2B4 SORL1

1.52e-051981787aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCellCOVID_non-vent-Lymphocytic-ILC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TSPOAP1 RNF213 STK10 PTPN4 UTRN ATP2B4 SORL1

1.57e-051991787df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCellCOVID_non-vent-Lymphocytic-ILC-NK_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TSPOAP1 RNF213 STK10 PTPN4 UTRN ATP2B4 SORL1

1.57e-051991787ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

REV3L GABBR2 IGDCC4 IGSF10 LRP6 C3 TNXB

1.57e-0519917878b86c69aaf60feff53aa782559cfece7342a23de
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Macroglial-Astrocyte|GW26 / Sample Type, Dataset, Time_group, and Cell type.

MYO10 CHDH SCRG1 TMEM132B CBS ADD3 ATP2B4

1.62e-052001787158ba898312c73bcb54c675a4860874a1dd58662
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SMCHD1 RNF213 SF1 RBM5 N4BP2L2 PCNX1

2.81e-05147178694998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PEG3 IGDCC4 TET1 GMEB1 CDH2 TNXB

4.51e-051601786778faada072e3abfa76a9a06fd4885fb63de7902
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOB CBS ITIH1 ITIH4 C3 NR1I3

4.67e-051611786274838cebdc7af1db32d309dfe42ef7ccd3c190b
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOB CBS ITIH1 ITIH4 C3 NR1I3

5.00e-05163178603d9fa615d9d02ef98e20f28a10aaa6894dd4960
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOB CBS ITIH1 ITIH4 C3 NR1I3

5.00e-0516317861c4de36cf8cdaabb981cda5c7ce7e5ae7b4280e3
ToppCelldroplet-Liver-Hepatocytes-18m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOB CBS ITIH1 ITIH4 C3 NR1I3

5.00e-0516317867e82c1b7849eca895732df2da74ac6430bd9ba7a
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

OBSCN TGM1 LLGL1 PRR14L SNAPC4 HEATR5B

5.92e-0516817868697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Myeloid-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBLAC2 ZFAT CDH23 FANCG SBF1 SORL1

6.32e-051701786f3d5678669dcaed1836014cea543758b7ccc6b46
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-mLTo|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGDCC4 SPTBN5 PTCH2 C3 FLRT2 FOXL1

6.32e-0517017867653f1205d4e62abe7e31b1d76f9bbd665e45667
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SMCHD1 RNF213 APOB N4BP2L2 PCNX1 UTRN

6.53e-0517117862e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TSPOAP1 SMCHD1 ADD3 PTPN4 PLIN1 UTRN

6.53e-051711786e1fe07652c10c37191d1471ddaea500f74269e0c
ToppCellfacs-Marrow-T_cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCRG1 ITIH1 GSDME C3 FOXL1 SORL1

6.96e-0517317860f9784b30c81a4a4940e0623cec60d596e9985d2
ToppCellfacs-Marrow-T_cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCRG1 ITIH1 GSDME C3 FOXL1 SORL1

6.96e-05173178660f79e0698a7cf7516690fb20f1b82ee46547699
ToppCellIIH-CD8-naive_CD4|IIH / Condition, Cell_class and T cell subcluster

FBLN7 ACTR3C OBSCN ZSCAN32 PDP2 FLRT2

6.96e-0517317864f2843371d18af766c1892529ce286f56c956fde
ToppCellCOVID-19_Mild-Neu_3|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

DDX55 GMEB1 RHBDD3 PKN1 PRR14L UTRN

7.66e-0517617862049767fd591045cfcf5b1071d80798e52843f27
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

BSPRY FER1L6 GRHL1 CELSR1 FAT2 PLIN1

7.66e-0517617868d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCellEpithelial-basal_cell|World / Lineage, Cell type, age group and donor

VWDE CNTN6 CYP2W1 GRHL1 CELSR1 FAT2

8.40e-051791786d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

LAMA3 ABCA7 CNTN6 TGM1 ALPP AGAP3

9.78e-051841786cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MATN3 LAMA3 ABCA7 CNTN6 TGM1 ALPP

9.78e-051841786ca940a4f4970285ed284d5517d142abab0682044
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

LAMA3 ABCA7 CNTN6 TGM1 ALPP AGAP3

9.78e-051841786bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

GAPVD1 SMCHD1 RNF213 SLC30A1 PDP2 EXOC4

1.01e-041851786a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

GAPVD1 SMCHD1 RNF213 SLC30A1 PDP2 EXOC4

1.04e-0418617868571956890fc9894d766ba294a28e376b4aba428
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)-|368C / Donor, Lineage, Cell class and subclass (all cells)

BSPRY PARP3 LAMA3 TGM1 C7orf25 DAAM2

1.10e-041881786c74771584b3ba9561a99a54bf55a9203ddf8eff8
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)|368C / Donor, Lineage, Cell class and subclass (all cells)

BSPRY PARP3 LAMA3 TGM1 C7orf25 DAAM2

1.10e-0418817869155b9a92496e75646778c025b02947e9e9ec73a
ToppCellNon-neuronal-Non-dividing-Radial_Glia-oRG/Astrocyte-7|World / Primary Cells by Cluster

MYO10 SCRG1 TMEM132B ADD3 NCAN DAAM2

1.17e-0419017868f1c490dd8e5f80382f5294fd1aa8cba4c3c647f
ToppCellNon-neuronal-Non-dividing-Radial_Glia-oRG/Astrocyte|World / Primary Cells by Cluster

MYO10 SCRG1 TMEM132B ADD3 NCAN DAAM2

1.17e-0419017867dbfd543398c63cbe1e68b54bcb5e2291f521935
ToppCellLAM-Epithelial-AT1|Epithelial / Condition, Lineage and Cell class

MATN3 LAMA3 PARP14 ABCA7 CNTN6 ALPP

1.20e-0419117863457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGM1 GSDME UBQLN3 C3 ROBO3 TNXB

1.20e-041911786b7713aba839e7a1f548b7b9d8893067bcc6d7ee7
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IGDCC4 IGSF10 HMCN2 PTCH2 FLRT2 TNXB

1.23e-0419217868d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCRG1 TTYH3 CBS IGDCC4 CELSR1 NCAN

1.23e-041921786261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SMCHD1 RNF213 SF1 N4BP2L2 PCNX1 SORL1

1.23e-04192178647646d7e4990be85072987f92bf18d52f8da752e
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

SMCHD1 RNF213 APOB KDM5D N4BP2L2

1.26e-04121178519333a660800b583fa27b495c1f7828e6636a257
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BAG1 CYP2W1 TGM1 FAT2 GSDME TMPRSS11D

1.27e-0419317867c34abdcb8839b9fb25457a79af6c5e7b9714b21
ToppCellfacs-Skin-Telogen-3m-Epithelial|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL13RA1 PEG3 MAP3K1 MAPRE1 MAPK1 UTRN

1.31e-0419417864d7fc4d0a55abb3b645116d13a983bbedc55f70c
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IGDCC4 IGSF10 HMCN2 PTCH2 DAAM2 FLRT2

1.31e-041941786439d3f17c1f4736122b330e98add9292c7036a8e
ToppCellfacs-Skin-Telogen-3m|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL13RA1 PEG3 MAP3K1 MAPRE1 MAPK1 UTRN

1.31e-041941786ba10fc5929649bb994c3f1d2ce6ca3167fa9b11b
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

CNKSR1 CDC42BPA LAMA3 PARP14 CELSR1 CEP170B

1.31e-04194178688db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

CNKSR1 CDC42BPA LAMA3 PARP14 CELSR1 CEP170B

1.31e-041941786a71728202493d4858342ea2756ea281cd0d99a3a
ToppCellfacs-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2C2 HDAC7 SF1 MAP3K1 SUN2 NR1I3

1.31e-04194178666c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCellfacs-Skin-Telogen|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL13RA1 PEG3 MAP3K1 MAPRE1 MAPK1 UTRN

1.31e-041941786bafecab8d48fc94ffd93f0d054b5f32c04b6b3f6
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO10 PEG3 KDM5D REV3L ROBO2 CDH2

1.34e-0419517867796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellcritical-Lymphoid-CTL|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TBC1D2B RNF213 PTPN4 SUN2 N4BP2L2 ATP2B4

1.38e-041961786c861f017aa9050282aa81c5a445bae399df00e4f
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MATN3 LAMA3 ABCA7 CNTN6 UTRN ALPP

1.38e-0419617866731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MATN3 LAMA3 ABCA7 CNTN6 UTRN ALPP

1.38e-041961786eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MATN3 LAMA3 ABCA7 CNTN6 UTRN ALPP

1.38e-0419617866856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MYO10 COL22A1 IGDCC4 ROBO2 FLRT2 CDH2

1.38e-041961786d5ed41fa111750e6b363c04cccc40a47dd774852
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

RNF213 ADD3 STK10 PTPN4 UTRN ATP2B4

1.42e-041971786836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 DNAH2 DNAH7 DZANK1 CROCC2 KCNN3

1.42e-04197178674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellAT1_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

MATN3 LAMA3 ABCA7 CNTN6 CDR2L TGM1

1.42e-04197178680d81be244c94c435accb643449b4ce6a3462c7f
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial|6_mon / Sample Type, Dataset, Time_group, and Cell type.

MYO10 SCRG1 ADD3 NCAN KCNN3 SORL1

1.42e-041971786965d5a3f8c9b12cb8a8d3429702ae29ebd8c6122
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial-Astroglia|6_mon / Sample Type, Dataset, Time_group, and Cell type.

MYO10 SCRG1 ADD3 NCAN KCNN3 SORL1

1.42e-0419717863f088eb29197bc575400d6dafd8083e69e4a149f
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IPO8 TTYH3 ATP9A GMEB1 ARHGEF37 BAG6

1.42e-041971786789c97ca9d1e28df3353140046047f11fbccc1d0
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MYO10 ADD3 IGSF10 ENAH ROBO2 FGFR4

1.42e-0419717860034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellBiopsy_IPF-Epithelial-AT1|Biopsy_IPF / Sample group, Lineage and Cell type

MATN3 LAMA3 ABCA7 CNTN6 TGM1 ALPP

1.46e-04198178675bdecbe111fededf6082b11de18b84ca308ef6d
ToppCellsystemic_lupus_erythematosus-treated|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SMCHD1 RNF213 ADD3 PTPN4 SUN2 N4BP2L2

1.46e-0419817868165ff735095c52994fb5057d89be93cc378b7da
ToppCellsystemic_lupus_erythematosus-flare|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SMCHD1 RNF213 ADD3 PTPN4 SUN2 N4BP2L2

1.46e-0419817864c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCellTracheal-10x5prime-Stromal-Chondrocytic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PAPPA2 GABRG2 FBLN7 MATN3 SCRG1 DAAM2

1.46e-041981786c72ef2ddcbb6dacbed4c6200d89e17d57314dcdc
ToppCellTracheal-10x5prime-Stromal-Chondrocytic-Chondrocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PAPPA2 GABRG2 FBLN7 MATN3 SCRG1 DAAM2

1.46e-04198178655f013e9e6587d9ece59751fa131b1d22d6cceea
ToppCell367C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SCRG1 ADD3 IGSF10 C3 ROBO3 TNXB

1.50e-0419917862aed8f4a225a3762a5e7ce99aacad9b2a37d61f1
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Radial_glial-oRG/Astroglia|6_mon / Sample Type, Dataset, Time_group, and Cell type.

MYO10 SCRG1 TMEM132B ADD3 NCAN KCNN3

1.50e-0419917860b96fad1be02f0fe7a608207770cc56a6b6b291e
ToppCell367C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SCRG1 ADD3 IGSF10 C3 ROBO3 TNXB

1.50e-041991786c40ca26345753a2197bd9389d7323f7491c1e11d
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TET1 DAAM2 DDX43 FLRT2 ZNF853 TNXB

1.50e-041991786a13f4b8a039304e685464cc8879659824cad5a3e
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ZFAT DNAH2 DNAH7 DNAH1 CELSR1 C3

1.50e-04199178660919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCellLPS_anti-TNF-Epithelial_airway|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ZFAT DNAH2 DNAH7 DNAH1 CELSR1 C3

1.50e-0419917866aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCellBronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SPTB LAMA3 ITIH4 DAAM2 GPAT2 FOXL1

1.50e-04199178678a9b26215874a46a910a4b93a51fcac1a597618
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PAPPA2 SCRG1 ADD3 IGSF10 C3 TNXB

1.54e-0420017860b2614b8513693dd508c9003699049efd9abac52
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

RPAP3 PFAS BRCA1 SUN2 PDP2 PKN1

1.54e-042001786691b3edf7d8449556e8bf611662eb85772959f0f
ToppCellBiopsy_Other_PF-Mesenchymal-Fibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

PAPPA2 SCRG1 IGSF10 HMCN2 C3 TNXB

1.54e-0420017869996b6887cf2b1936e10a1aa396f09fd8da5f4c4
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Macroglial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

CHDH RNF213 SCRG1 COL22A1 CBS ATP2B4

1.54e-0420017863a954d9d542e52c9b181f0850a09b1bff0a0c82d
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMCHD1 RNF213 PARP14 SF1 N4BP2L2 UTRN

1.54e-04200178612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-2,_SCARA5|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PAPPA2 SCRG1 ADD3 IGSF10 C3 TNXB

1.54e-0420017868d2ceb2080c67b20f452eeca605aa27a58033c04
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

RPAP3 PFAS BRCA1 SUN2 PDP2 PKN1

1.54e-04200178636a110aa91a791fdf1142e7869e8aa0d342402d0
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL22A1 IGDCC4 ENAH ROBO2 DAAM2 CDH2

1.54e-0420017863c898e81444b001835c3f1bbc68183078701b135
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells-Neuroepithelial_cell|GW08 / Sample Type, Dataset, Time_group, and Cell type.

RPAP3 PFAS BRCA1 SUN2 PDP2 PKN1

1.54e-0420017864e077aa7faddcebdfc54667f8b3990704441005b
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL22A1 IGDCC4 ENAH ROBO2 DAAM2 CDH2

1.54e-0420017863eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

RPAP3 PFAS BRCA1 SUN2 PDP2 PKN1

1.54e-042001786d17ba4239e1fd702a3d757687110f0f2c6f91ef7
ToppCellParenchyma_COVID-19-Stromal-TX-Fibroblasts-2,_SCARA5|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PAPPA2 SCRG1 ADD3 IGSF10 C3 TNXB

1.54e-042001786c338a08c1605527ab9aaf62ea151a19e8469dc6d
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FBLN7 BSPRY DNAH1 IKBKE ALPP

1.70e-0412917852f30b4897343586c9b49a1d2bec3007ec737085c
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-9|TCGA-Brain / Sample_Type by Project: Shred V9

DNAH7 ADD3 AGO3 KCNN3 DAAM2

2.03e-0413417852647453f44b0e0a8f27ef9bba750e99eb40efc8b
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

SMCHD1 RNF213 CYP2W1 PCNX1 UTRN

2.10e-041351785ae2d3a42e567b5bade304c0caa497eb725be3565
DiseaseFamilial vesicoureteral reflux

ROBO2 TNXB

1.06e-0431762cv:C4706552
DiseaseFamilial vesicoureteral reflux

ROBO2 TNXB

1.06e-0431762C4706552
DiseaseVesicoureteral reflux

ROBO2 TNXB

1.06e-0431762cv:C0042580
DiseaseVesico-Ureteral Reflux

ROBO2 TNXB

2.11e-0441762C0042580
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5C KDM5D

2.11e-0441762DOID:0060809 (implicated_via_orthology)
Diseasesolanidine measurement

CYP2D7 CYP2D6

2.11e-0441762EFO_0800966
DiseaseFamilial Alzheimer Disease (FAD)

CYP2D6 IDE ABCA7 NECTIN2 SORL1

3.40e-041001765C0276496
Diseasevesicoureteral reflux (is_implicated_in)

ROBO2 TNXB

3.50e-0451762DOID:9620 (is_implicated_in)
DiseaseAlzheimer's Disease

CYP2D6 IDE ABCA7 NECTIN2 SORL1

3.56e-041011765C0002395
DiseaseAlzheimer disease

ABCA7 ITIH1 CDR2L NECTIN2 KCNN3 PCNX1 ADAM17 TNXB EXOC4 SORL1

7.03e-0448517610MONDO_0004975
Diseasemyoclonic-atonic epilepsy (implicated_via_orthology)

ROBO2 ROBO3

7.28e-0471762DOID:0060475 (implicated_via_orthology)
Diseasemean corpuscular hemoglobin concentration

DR1 ZFAT SPTB PFAS SMG5 SLC30A1 ABCA7 HDAC7 IGDCC4 FANCG NCAN NECTIN2 N4BP2L2 ARHGEF37 ZNF853 ATP2B4

9.96e-04110517616EFO_0004528
Diseasevital capacity

PAPPA2 ZFAT IPO8 RDH14 APOB ATP9A MAP3K1 CROCC2 LRP6 FLRT2 FGFR4 SNAPC4 ZNF853 CDH2 UTRN TNXB AGAP3

1.21e-03123617617EFO_0004312
DiseaseMental deterioration

NECTIN2 SORL1

1.24e-0391762C0234985
DiseaseLiver Diseases, Parasitic

PEG3 ROBO2

1.24e-0391762C0023897
DiseaseMild cognitive disorder

NECTIN2 SORL1

1.24e-0391762C1270972
Diseaselung non-small cell carcinoma (is_implicated_in)

MAP3K1 BRCA1 XPO5 FGFR4 BAG6

1.51e-031391765DOID:3908 (is_implicated_in)
DiseaseFanconi anemia (is_implicated_in)

FANCG BRCA1

1.54e-03101762DOID:13636 (is_implicated_in)
Diseasecerebral cavernous malformation (implicated_via_orthology)

CDC42BPA RNF213

1.88e-03111762DOID:0060669 (implicated_via_orthology)
Diseaseage-related macular degeneration

NECTIN2 KCNN3 C3 TNXB

2.01e-03891764EFO_0001365
Diseaseautism spectrum disorder (implicated_via_orthology)

KDM5C NDST2 KDM5D RIMS4 MAPK1

2.23e-031521765DOID:0060041 (implicated_via_orthology)
DiseaseMouth Diseases

FANCG BRCA1

2.24e-03121762C0026636
Diseasehepatocellular carcinoma (is_marker_for)

KDM5C PFAS ITIH4 MAP3K1 TET1 ENAH FGFR4

2.28e-033011767DOID:684 (is_marker_for)
Diseaseimmunoglobulin isotype switching measurement

LAMA3 ITIH1 ATP2B4

2.31e-03441763EFO_0010128
DiseaseBipolar Disorder

BAG1 CBS ITIH1 ITIH4 CNTN6 ADD3 NCAN KCNN3 MAPK1

2.36e-034771769C0005586
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

MAP3K1 BRCA1 FGFR4

2.46e-03451763DOID:3748 (is_implicated_in)
DiseaseSchizophrenia

GABRG2 CYP2D6 BAG1 IDE CBS ITIH1 BRCA1 NCAN TET1 KCNN3 DAAM2 MAPK1 TNXB

2.56e-0388317613C0036341
Diseaseamyotrophic lateral sclerosis (biomarker_via_orthology)

ITIH4 C3

2.64e-03131762DOID:332 (biomarker_via_orthology)
DiseaseAcute Confusional Senile Dementia

CYP2D6 IDE ABCA7 NECTIN2

2.96e-03991764C0546126
DiseaseAlzheimer's Disease, Focal Onset

CYP2D6 IDE ABCA7 NECTIN2

2.96e-03991764C0750900
DiseaseAlzheimer Disease, Early Onset

CYP2D6 IDE ABCA7 NECTIN2

2.96e-03991764C0750901
DiseasePresenile dementia

CYP2D6 IDE ABCA7 NECTIN2

2.96e-03991764C0011265
DiseaseAlzheimer Disease, Late Onset

CYP2D6 IDE ABCA7 NECTIN2

2.96e-03991764C0494463
Diseasedystonia (is_implicated_in)

TSPOAP1 NUP54

3.07e-03141762DOID:543 (is_implicated_in)
DiseaseImpaired cognition

NECTIN2 SORL1

3.07e-03141762C0338656
Diseaseamenorrhea, response to antineoplastic agent

CALCR APOB

3.53e-03151762EFO_0010269, GO_0097327
Diseasephospholipids in IDL measurement

APOB CYP2W1 NECTIN2

3.72e-03521763EFO_0022164
Diseasetriglycerides to total lipids in very large VLDL percentage

APOB CYP2W1 NECTIN2

3.93e-03531763EFO_0022340
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5C KDM5D

4.02e-03161762DOID:0050888 (implicated_via_orthology)
Diseasefocal segmental glomerulosclerosis

IPO4 FGFR4

4.02e-03161762EFO_0004236
Diseasesickle cell anemia (is_implicated_in)

APOB C3

4.02e-03161762DOID:10923 (is_implicated_in)
DiseaseCiliopathies

OFD1 CDH23 NEK1 BBS12

4.32e-031101764C4277690
Diseasesmoking behavior

GAPVD1 CDC42BPA REV3L TMEM132B ITIH4 EXOC4 SORL1

4.52e-033411767EFO_0004318
Diseasefree cholesterol to total lipids in large HDL percentage

APOB CYP2W1 NECTIN2

4.59e-03561763EFO_0022279
Diseaseinterleukin-6 measurement

ENAH KCNN3 MAPK1 ATP2B4

4.61e-031121764EFO_0004810
Diseasecholesterol in IDL measurement

APOB CYP2W1 NECTIN2

5.06e-03581763EFO_0021899
Diseasealpha synuclein measurement

COG2 ENAH

5.08e-03181762EFO_0009323
Diseasebreast cancer (is_marker_for)

KDM5C BAG1 MAP3K1 BRCA1 MAPK1

5.15e-031851765DOID:1612 (is_marker_for)
Diseasecolon cancer (is_marker_for)

KDM5C BRCA1 FGFR4

5.31e-03591763DOID:219 (is_marker_for)
Diseasefree cholesterol to total lipids in very large VLDL percentage

APOB CYP2W1 NECTIN2

5.31e-03591763EFO_0022289
Diseasetotal lipids in IDL

APOB CYP2W1 NECTIN2

5.56e-03601763EFO_0022161
Diseasefree cholesterol in IDL measurement

APOB CYP2W1 NECTIN2

5.83e-03611763EFO_0022181

Protein segments in the cluster

PeptideGeneStartEntry
DVPLGQQLLRAVVED

AGAP3

746

Q96P47
VDGQPSLQQVLERVD

ERI3

211

O43414
VEELQAQVEQLRGLE

CDR2L

126

Q86X02
RPLEQENERLQTLVG

CDR2L

186

Q86X02
VQVQPGVDIIRTNLE

BAG6

826

P46379
GEESAEIIPLNIIEQ

CALCR

456

P30988
EQEERIQLQKVLGPS

ADD3

271

Q9UEY8
IRSRLQQLPQGDLDV

ARHGEF37

56

A1IGU5
ISNPLAQEIGEERIE

DEPDC4

191

Q8N2C3
TINLRNPVLQQVLEG

GSDME

136

O60443
NPVLQQVLEGRNEVL

GSDME

141

O60443
QEQELTVALGQPVRL

FGFR4

41

P22455
VLLDGVQNPRAEDLV

C3

306

P01024
PDVQGRVQEELDRVL

CYP2W1

316

Q8TAV3
VDGQILGQLRPLTEE

BIRC7

51

Q96CA5
QDLAQVVEEVIGVPQ

BAG1

171

Q99933
EPRLQQLGLLEEEQL

CD209

6

Q9NNX6
VQVPEDVGLNTAVLR

CELSR1

466

Q9NYQ6
PLQLENGQTVERTVA

AGO3

296

Q9H9G7
PLEASGEQVRLQRQI

CEP170B

376

Q9Y4F5
NQPVRIVLIEGDLTE

BBS12

351

Q6ZW61
LVGIRVLDINDNDPV

CDH23

1836

Q9H251
VGLPVDLQELRVDEN

FLRT2

176

O43155
SIIRNGQLIQLPVAE

ATP2B4

191

P23634
VGPEQDRLLQDVGLV

ABCA7

916

Q8IZY2
AVVDPQTRVLGVENL

CHDH

526

Q8NE62
VLPNGVLQILDVQES

IGDCC4

191

Q8TDY8
PEQQETVLDGNLIIR

ITIH4

226

Q14624
VNIQQPLIREDGTVL

NR2C2

246

P49116
VILGEPEKEQRVQQL

TSPOAP1

326

O95153
QPQVGTLEERNDVVE

OFD1

701

O75665
CVPRLNEGDQVVLIN

PTPN4

556

P29074
EELEVRILVQARPGQ

GPHN

441

Q9NQX3
QDTELELDGQQVVVP

PARP3

481

Q9Y6F1
GQVLVLELSDVPVEQ

LLGL1

536

Q15334
NQIRSIPDSVGELQV

LRRC57

141

Q8N9N7
VQNQRIRGEEPAVTE

DPH5

201

Q9H2P9
RPGVTQRDEIDQLQE

NR1I3

276

Q14994
SQPEDQRERLLQGVQ

PHLDB3

206

Q6NSJ2
QQIVLQDERGVDPDL

DAAM2

406

Q86T65
LILVQNLEGPQTLEV

FBLN7

396

Q53RD9
ENIIGINDIIRAPTI

MAPK1

81

P28482
ELGLVEQDIIEIPQL

PADI6

576

Q6TGC4
LNQEEVESLNRPITG

nan

441

O00370
AIIVTDGRPQDQVNE

MATN3

191

O15232
IVPLENGEVVVSLIN

LAMA3

221

Q16787
EVLDGLNPIQTDVER

LAMA3

2301

Q16787
VPTVGDVRQDNLEID

NEK1

1066

Q96PY6
EEQNPNVQDILGELR

NELFA

111

Q9H3P2
EELLRGVQQRLIQAP

GMEB1

281

Q9Y692
RGIEILNQVQESLPE

ITIH1

376

P19827
QNDVVVVRGSLVELP

HMCN2

3421

Q8NDA2
QQLLREREVGIPPEQ

ACTR3C

76

Q9C0K3
IVLLEGITPNIQLED

KIAA1109

2836

Q2LD37
IQEVQPEEVLVISLG

GAPVD1

506

Q14C86
QLVPILANILEVEQA

IKBKE

276

Q14164
LLERGQQLGVEVPEA

KDM5D

891

Q9BY66
PQGVLERNNVITLNI

GLB1

451

P16278
TQEVENLVRAGLRNP

DDX55

206

Q8NHQ9
RVQIVDPSQILEGIN

PCNX1

2246

Q96RV3
TVPGVELLRVQAIDQ

FAT2

1461

Q9NYQ8
RNLIEAETEGQPLQL

KCNN3

196

Q9UGI6
PLIGSLIQERQEIIA

FAM214A

361

Q32MH5
RGEEILTPLNVQQAV

MYO10

381

Q9HD67
QQVTLLVAGPEVEEQ

PDZD3

291

Q86UT5
RIVLEDSNILQPVGL

LRP6

1136

O75581
LIVQPNTRLEGSDVQ

DPP3

671

Q9NY33
QVGDLIIVEKNQRVP

ATP9A

156

O75110
ERVLETQEQQGPRLE

FANCG

101

O15287
LGIPEEELLRQQQEL

DR1

111

Q01658
KPGQTEIQVNLRELE

NUDT13

281

Q86X67
QQLIPELVRNGDEEN

RBM5

596

P52756
PQVVLRIQGLNVEAA

PEG3

1381

Q9GZU2
IEVPLNERICLQVGS

IL13RA1

86

P78552
QTPVDQLLQDGLQLR

SBF1

971

O95248
DGDLPEQENVLQRVL

PLIN1

11

O60240
VQDIIVNPDALGVLR

PRSS41

131

Q7RTY9
EGQLPQVVEELRDLQ

OBSCN

5256

Q5VST9
QVVEELRDLQVAPGT

OBSCN

5261

Q5VST9
RVQLDTIQGELNAPT

NUP54

411

Q7Z3B4
RLQLSLGIIPVEEEN

ALPP

16

P05187
VQQGDLARLPVDVVV

PARP14

806

Q460N5
EEKQNIPGEIERILN

KCNA10

471

Q16322
EGLNPIVSEEQIRLQ

PAPPA2

536

Q9BXP8
QLSPEQINEVLRAGE

PDP2

76

Q9P2J9
DQELLQITPQGTRDE

BRCA1

201

P38398
QLLGQVVAEERPDLE

DNAH1

3356

Q9P2D7
GENVTVENQPRLLLE

EXOC4

326

Q96A65
VTQRLNGEIQALELP

APOB

2446

P04114
QVLPNGTLSIQRVEI

IGSF10

1701

Q6WRI0
GEEQNRVQLLALLVP

HEATR5B

1966

Q9P2D3
EQPLISAGENRVQVL

GRHL1

101

Q9NZI5
PAQLGVVLDLQVQEL

BSPRY

351

Q5W0U4
GVENLEIRDIQTINP

CARD6

361

Q9BX69
QPLLGLDTVIQRLED

CROCC2

16

H7BZ55
GPELLQVTRVDRENI

C7orf25

216

Q9BPX7
VQQEIDDVIGQVRRP

CYP2D6

331

P10635
QDQLLGIVVAQERPD

DNAH7

3111

Q8WXX0
VPEGDVTVILNNLLE

GABRG2

61

P18507
VQAVIEQLLVSGQPL

GPAT2

271

Q6NUI2
AQELQEGQRCVVILP

CBS

361

P35520
ERLNPEERIQIENGT

CNTN6

356

Q9UQ52
QTLPIEERENIDIQG

COL22A1

386

Q8NFW1
RPELQQVTVDGLEVL

FKTN

216

O75072
NEGENDPVLQRIVDI

MAPRE1

231

Q15691
QAVQPTLILQDGDVI

MBLAC2

141

Q68D91
GVLPAVELAIEQIRN

GABBR2

76

O75899
AIQDAPEQRVTLNGI

FOXL1

61

Q12952
VDIIIATPGRLNDLQ

DDX53

346

Q86TM3
LETRPNQEGIDVRQE

IDE

226

P14735
VQNGPSQEELEIQRR

ENAH

131

Q8N8S7
NQLSVPLGQLREEVL

COG2

86

Q14746
ELQVGPQEQELRQLL

HDAC7

56

Q8WUI4
AIPVLVQRGADIDQQ

DZANK1

656

Q9NVP4
QGPQITRNLLEIEDI

DNAH2

416

Q9P225
PRIVDEEAIVILQGQ

CFAP47

211

Q6ZTR5
LTGREDLQPVQIQSL

IPO4

531

Q8TEX9
VPLEENVNRRVLEEG

CCDC124

126

Q96CT7
VDIIIATPGRLNDLQ

DDX43

366

Q9NXZ2
DINGNQVENPIDIVI

CDH2

241

P19022
GRADVIADIQTIPIQ

PRR14L

696

Q5THK1
TIREEIPENVLIGNL

PCDH11Y

61

Q9BZA8
QIRDNIVEGIIRSPD

IPO8

91

O15397
PQLQVENGEDIIIIQ

MAP3K1

1206

Q13233
EARQLVGENIDPVVT

FER1L6

91

Q2WGJ9
VLLREPALQEVQQVH

SYNC

201

Q9H7C4
RIPRADELNQTGQIL

UTRN

741

P46939
LQNLIEGSEPILEER

UTRN

1611

P46939
NLQLSLPREAEGVIV

SORL1

1656

Q92673
QLVQDLLTQVRAGPE

RIN1

381

Q13671
VINGRDLQNPIIVQL

SMCHD1

1271

A6NHR9
GLQPVLLQDRRVENV

TMCO4

481

Q5TGY1
NIRLQAELEEGENPV

SMG5

396

Q9UPR3
IGLQERNGQLEVDII

RIMS4

121

Q9H426
NVVISVPLNLVREGD

TMEM132B

281

Q14DG7
EPGEVGQLLQQTEVL

PLEKHG4

366

Q58EX7
LAELEQERPGVVLQQ

PLEKHG4

576

Q58EX7
LLVLGQQPVISQEDR

RFFL

131

Q8WZ73
IQTARQEGENILTPE

PTCH2

116

Q9Y6C5
QVVRGIEDEQDLVPL

NCAN

141

O14594
ALIVQVDSEEQLPGR

SPATA31E1

1101

Q6ZUB1
LAAPGVQQQLELERE

PKN1

26

Q16512
QEEPRLDVLINNAGI

RDH14

131

Q9HBH5
LPEGVADLTQIDVNV

SCRG1

41

O75711
EGLTREILREQPDNI

SPA17

21

Q15506
PGLEDVVQEVQQVLS

INTS5

116

Q6P9B9
IELIPNDQLVAVISG

CDC42BPA

1271

Q5VT25
LQECGPTQVQLRDVL

SPTBN5

1006

Q9NRC6
QDTQVLPDIETLIGV

TET1

161

Q8NFU7
GIQIEQIRILKSPQE

ADAM17

276

P78536
TDSRLQIQPGDEVVQ

CNKSR1

231

Q969H4
PVRVQQEIDDVIGQV

CYP2D7

346

A0A087X1C5
LEPSERRLQVLQEGV

RHBDD3

186

Q9Y3P4
VPELRQGQVRIISND

TMPRSS11D

321

O60235
LAQLGLEPRDEVVQA

TOR2A

276

Q5JU69
LQVIERQGPRALTEE

RNF213

3231

Q63HN8
DGDRVSNIVVQPIVN

VWDE

386

Q8N2E2
GDRLDPTAVNILQQI

ZFAT

1121

Q9P243
PTAVNILQQIIELGA

ZFAT

1126

Q9P243
LVEDVQRAPGQQVLD

ZSCAN32

111

Q9NX65
AEEVGLLPQQIQAVR

SUN2

436

Q9UH99
PQHVAVILNQEIREL

REV3L

3061

O60673
IIEETGNLIQTIDVP

RPAP3

436

Q9H6T3
RQLEAVVEGLVATQP

PPM1M

146

Q96MI6
GLVLEVQEPDLAQVL

PFAS

951

O15067
QGLAEVAVRLQEPIV

ROBO3

666

Q96MS0
VEVLTLNQEVAGPRN

ZNF274

111

Q96GC6
TQGEQLEVPERLLVV

SPSB2

156

Q99619
DRGLTEPQIQVVCRQ

STK10

126

O94804
PRLGEELQVTTVTQN

TNXB

1776

P22105
LNREEIPVNDGIELL

XPO5

521

Q9HAV4
QLLIVDGQELRTNPA

NDST2

771

P52849
EPVQLETLSIRGNNI

SNRPD1

51

P62314
RDPRATIQEQGTLQI

ROBO2

461

Q9HCK4
TPRVEDVLQRGQQLV

SPTB

1531

P11277
ELQEGAAPLEQEIIR

ZNF862

766

O60290
ETRPGQRELQLQQLE

ZNF853

81

P0CG23
PVDLGSEQELEQQRQ

ZNF853

326

P0CG23
QQEVQLELTPVELGA

ZNF853

381

P0CG23
LELTPVELGAQQQEV

ZNF853

386

P0CG23
TEALLGRSIQPEQVQ

SLC30A9

446

Q6PML9
GRSIQPEQVQRLTEL

SLC30A9

451

Q6PML9
PAVVQTQADGLREQL

SNAPC4

766

Q5SXM2
DRITLELLIGNNPEV

TGM1

161

P22735
DTVEVQVNGNLVREP

SLC30A1

216

Q9Y6M5
DPLLRVQEVLNGTEV

TTYH3

341

Q9C0H2
EDQGPTREVIAQLLE

TBC1D2B

556

Q9UPU7
QIEQGLQVLATEAPR

UBQLN3

526

Q9H347
QIRNILKQGIETPED

SF1

221

Q15637
EVIDIRGPIRDTLQN

UBXN11

346

Q5T124
LGVEVPEAQQLQRQV

KDM5C

911

P41229
IDQGRSPVIIDNTNI

N4BP2L2

466

Q92802
LLETGAQDVRVQVLP

NECTIN2

26

Q92692