Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainSAA

SAA1 SAA2 SAA4

3.99e-0641883PS00992
DomainSAA

SAA1 SAA2 SAA4

3.99e-0641883SM00197
DomainSAA

SAA1 SAA2 SAA4

3.99e-0641883PF00277
DomainSerum_amyloid_A

SAA1 SAA2 SAA4

9.89e-0651883IPR000096
Domain-

EML6 DCAF5 MAPK8IP3 SEMA6D EML5 TECPR2 SEC13 BRWD1 COPA DTL TEP1 SCAP WDR82

3.42e-05333188132.130.10.10
DomainWD40/YVTN_repeat-like_dom

EML6 DCAF5 MAPK8IP3 SEMA6D EML5 TECPR2 SEC13 BRWD1 COPA DTL TEP1 SCAP WDR82

3.64e-0533518813IPR015943
DomainWD40_repeat_dom

EML6 DCAF5 MAPK8IP3 EML5 TECPR2 SEC13 BRWD1 COPA DTL TEP1 SCAP WDR82

4.95e-0529718812IPR017986
DomainWD40

EML6 DCAF5 EML5 TECPR2 SEC13 BRWD1 COPA DTL TEP1 SCAP WDR82

8.90e-0526818811SM00320
DomainARHGEF5_35

ARHGEF5 ARHGEF35

1.01e-0421882PF15441
DomainARHGEF5/35_N

ARHGEF5 ARHGEF35

1.01e-0421882IPR029212
DomainWD40_repeat

EML6 DCAF5 EML5 TECPR2 SEC13 BRWD1 COPA DTL TEP1 SCAP WDR82

1.01e-0427218811IPR001680
DomainWD_REPEATS_1

EML6 DCAF5 EML5 TECPR2 SEC13 BRWD1 COPA DTL TEP1 SCAP WDR82

1.23e-0427818811PS00678
DomainWD_REPEATS_2

EML6 DCAF5 EML5 TECPR2 SEC13 BRWD1 COPA DTL TEP1 SCAP WDR82

1.27e-0427918811PS50082
DomainWD_REPEATS_REGION

EML6 DCAF5 EML5 TECPR2 SEC13 BRWD1 COPA DTL TEP1 SCAP WDR82

1.27e-0427918811PS50294
DomainWD40_repeat_CS

EML6 EML5 BRWD1 COPA DTL TEP1 SCAP WDR82

2.61e-041641888IPR019775
DomainWD40

EML6 DCAF5 EML5 SEC13 BRWD1 COPA DTL TEP1 SCAP WDR82

3.04e-0425918810PF00400
DomainZF_PHD_2

KMT2B ASH1L DIDO1 MLLT10 UHRF1 ASXL2

3.97e-04951886PS50016
DomainZF_PHD_1

KMT2B ASH1L DIDO1 MLLT10 UHRF1 ASXL2

4.20e-04961886PS01359
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TANC2 USP34 GBF1 KMT2B FHIP1B ZZEF1 TNFRSF21 MAPK8IP3 PIK3C2B AHNAK OSBPL5 CAMSAP1 ARHGAP21 NOTCH1 RHBDF1 PUF60 MIB2 MLLT10 TEP1 HDAC7 KCNH3 SH3PXD2B CELSR1 SCAP TLN1 EIF4G1 AHNAK2

3.05e-1011052012735748872
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

SERBP1 GBF1 SRPRA TMEM214 PEX11B TMCO4 AHNAK OSBPL8 CAMSAP1 PUF60 POR SH3PXD2B TLN1 EIF4G1 TMEM209 ZW10 PBXIP1 VPS13B AHNAK2

1.04e-095682011937774976
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TANC2 TNK1 GBF1 CEP350 PIK3C2B NFATC3 AHNAK OSBPL8 MAP3K9 CAMSAP1 ARHGAP21 DOP1B NEDD4L ARHGEF5 DTL RAB11FIP1 HDAC7 SH3PXD2B FAM171A2 EIF4G1 ANKRD17 PPP1R12C AHNAK2

1.31e-098612012336931259
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

GBF1 SPATA31E1 APOBR PICALM ZNF469 NFKBIL1 KDR CAMSAP1 NYAP1 NOTCH1 NEDD4L ARHGEF5 TEX14 MLLT10 TLN1

3.70e-084302011535044719
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

SERBP1 GBF1 TNRC6B SRPRA CEP350 AHNAK NUFIP2 CAMSAP1 NOP2 COPA EGLN1 SH3PXD2B TLN1 EIF4G1 ANKRD17 WDR82 EIF3D IK AHNAK2

5.12e-087242011936232890
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

USP34 SERBP1 AHNAK NUFIP2 POP1 OSBPL8 NOP2 SEC13 CHERP COPA PUF60 NUP88 DIDO1 TLN1 EIF4G1 ANKRD17 EIF3D IK

5.63e-086532011822586326
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

SRPRA TMEM214 PEX11B MAGED2 NUFIP2 OSBPL8 COPA INTS7 DYNC2H1 DTL NUP88 DNAH2 POR SCAP FAM171A2 TLN1 EIF4G1 TMEM209 MTR ANKRD17 ZW10

1.53e-079422012131073040
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SERBP1 ERCC6 KMT2B RPP40 TNRC6B SRPRA TMEM214 NUFIP2 POP1 OSBPL8 RAC1 SEC13 SAMD1 RHBDF1 INTS7 DIDO1 MSL1 RAB11FIP1 CELSR1 TLN1 EIF4G1 ANKRD17 WDR82 EIF3D IK PBXIP1 PPP1R12C

1.72e-0714972012731527615
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

SERBP1 GAPDH TNRC6B SRPRA TMEM214 MAGED2 AHNAK NUFIP2 OSBPL8 CAMSAP1 ARHGAP21 NOTCH1 COPA EGLN1 TLN1 EIF4G1 ANKRD17 HDGF

1.86e-077082011839231216
Pubmed

The human serum amyloid A protein (SAA) superfamily gene cluster: mapping to chromosome 11p15.1 by physical and genetic linkage analysis.

SAA1 SAA2 SAA4

1.90e-07320138188252
Pubmed

Expression of SAA1, SAA2 and SAA4 genes in human primary monocytes and monocyte-derived macrophages.

SAA1 SAA2 SAA4

1.90e-073201331100086
Pubmed

Characterization of human serum amyloid A protein isoforms separated by two-dimensional electrophoresis by liquid chromatography/electrospray ionization tandem mass spectrometry.

SAA1 SAA2 SAA4

1.90e-07320138783012
Pubmed

Widespread expression of serum amyloid A in histologically normal human tissues. Predominant localization to the epithelium.

SAA1 SAA2 SAA4

1.90e-07320139815279
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

SERBP1 GBF1 GAPDH SELENOH TNRC6B SRPRA CEP350 MAGED2 AHNAK NUFIP2 POP1 OSBPL8 NOP2 RAC1 SEC13 NEDD4L COPA PUF60 DIDO1 MSL1 TLN1 EIF4G1 UHRF1 ANKRD17 WDR82

4.21e-0713712012536244648
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

KMT2B SRPRA TMEM214 PEX11B PRDM11 NFIX AHNAK NFKBIL1 POP1 NOP2 SAMD1 CHERP COPA INTS7 NUP88 DIDO1 MSL1 TMEM209 UHRF1 INTS4 WDR82 ASXL2 IK L3MBTL3

5.41e-0712942012430804502
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

SERBP1 GAPDH TNRC6B PICALM AHNAK NUFIP2 CAMSAP1 NOP2 ARHGAP21 CHERP PUF60 EGLN1 DUT NUP88 DIDO1 NUDCD3 TLN1 ANKRD17 EIF3D AHNAK2

5.77e-079342012033916271
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TNRC6B FHIP1B DCAF5 SEMA6D NUFIP2 NAV3 ARHGAP21 DOP1B NEDD4L TLN1 PPIP5K1 ASXL2 VPS13B

8.29e-074072011312693553
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

USP34 GBF1 HECW1 TNRC6B PASK OSBPL8 DOP1B THSD7A SCAP TLN1

8.47e-072252011012168954
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TANC2 HECW1 TNRC6B PICALM MAPK8IP3 MAGED2 NFATC3 NUFIP2 CAMSAP1 NOP2 ARHGAP21 RAC1 NEDD4L DIDO1 GRIK3 SH3PXD2B FAM171A2 EIF4G1 ANKRD17 UNC13A

9.24e-079632012028671696
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

USP34 SERBP1 GAPDH PDHB TNRC6B SRPRA DCAF5 MAGED2 NUFIP2 POP1 OSBPL8 NOP2 CHERP COPA EIF4G1 UHRF1 ANKRD17 WDR82 EIF3D UTP14C

1.05e-069712012033306668
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

SERBP1 ADARB1 AHNAK POP1 KDR CAMSAP1 NOP2 PPIP5K1 VPS13B UTP14C

1.21e-062342011036243803
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

USP34 SERBP1 GBF1 GAPDH PDHB RPP40 ZZEF1 MAGED2 AHNAK POP1 SEC13 COPA PUF60 DUT NUP88 NUDCD3 TLN1 EIF4G1 PNMA2 MTR ZFYVE19 EIF3D ZW10 AHNAK2 HDGF

1.24e-0614552012522863883
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

SERBP1 GAPDH INSRR MAGED2 AHNAK DIDO1 LAMC2 TLN1 EIF4G1 MMRN2 PBXIP1 AHNAK2

1.42e-063602011233111431
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

USP34 ASH1L DCAF5 EML5 POP1 MAP3K9 ARHGAP21 BRWD1 OGFRL1 RHBDF1 DTL DIDO1 ZNF101 SLC6A2 SH3PXD2B SCAP ANKRD17 ASXL2 IK VPS13B UTP14C

1.47e-0610842012111544199
Pubmed

Mapping of the mouse serum amyloid A gene cluster by long-range polymerase chain reaction.

SAA1 SAA2 SAA4

1.89e-06520138824159
Pubmed

Structure of the mouse Saa4 gene and its linkage to the serum amyloid A gene family.

SAA1 SAA2 SAA4

1.89e-06520138661036
Pubmed

Maternal siRNA silencing of placental SAA2 mitigates preterm birth following intrauterine inflammation.

SAA1 SAA2 SAA4

1.89e-065201336211368
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

SERBP1 DACT2 TMEM214 NUFIP2 NOP2 ARHGAP21 SEC13 CHERP COPA INTS7 DYNC2H1 NUP88 DNAH2 DIDO1 RAB11FIP1 SCAP EIF4G1

2.12e-067542011735906200
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TANC2 USP34 ERCC6 ASH1L TNRC6B SOWAHC ZZEF1 DCAF5 PASK ZNF469 HMCN2 EML5 NFKBIL1 TSR3 BRWD1 SAMD1 RAB11FIP1 TEP1 PNMA2 MTR ANKRD17

2.32e-0611162012131753913
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PDHB SRPRA CEP350 AHNAK NUFIP2 UNG NOTCH1 PDPR COPA POR TNS2 NUDCD3 RAB11FIP1 FAM171A2 PNMA2 INTS4 WDR82 IK L3MBTL3 PPP1R12C

3.37e-0610492012027880917
Pubmed

Regulation of amyloid A gene expression in cultured cells.

GAPDH SAA1 SAA2

3.76e-06620133221863
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

EML6 AHNAK CAMSAP1 NOP2 COPA LAMC2 MSL1 SH3PXD2B TLN1 EIF4G1 AHNAK2

4.17e-063322011137433992
Pubmed

Defining the membrane proteome of NK cells.

SERBP1 GBF1 GAPDH PEX11B APOBR PICALM CEP350 CLCN3 MAGED2 AHNAK NUFIP2 OSBPL5 OSBPL8 SCP2 CHERP COPA POR EIF4G1 ANKRD17 EIF3D ZW10

4.69e-0611682012119946888
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

SRPRA TMEM214 PICALM POP1 OSBPL5 SAMD1 INTS7 DIDO1 UHRF1 EIF3D IK ZW10

5.40e-064102011226949251
Pubmed

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

ERCC6 HECW1 PEX11B POP1 OSBPL8 SAMD1 DIDO1 INTS4 ASXL2 L3MBTL3

6.16e-062812011024163370
Pubmed

Serum Amyloid A-Mediated Inflammasome Activation of Microglial Cells in Cerebral Ischemia.

SAA1 SAA2 AGER

1.04e-058201331611307
Pubmed

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.

SERBP1 SRPRA TMEM214 NUFIP2 OSBPL5 OSBPL8 NOTCH1 POR TLN1 TMEM209 PBXIP1

1.31e-053752011132788342
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

SERBP1 CEP350 AHNAK POP1 NOP2 SEC13 CHERP COPA DTL NUP88 MSL1 CRY2 TLN1 EIF4G1 WDR82 ASXL2 EIF3D ZW10 VPS13B PPP1R12C

1.38e-0511552012020360068
Pubmed

A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic protein 1 in lymphopoiesis and innate immunity.

SAA1 SAA2 CD69

1.56e-059201319015308
Pubmed

Characterization of high affinity binding between laminin and the acute-phase protein, serum amyloid A.

SAA1 SAA2 SAA4

1.56e-05920138995276
Pubmed

The gene encoding the mouse serum amyloid A protein, apo-SAA5, maps to proximal chromosome 7.

SAA1 SAA2 SAA4

1.56e-05920137607707
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

GBF1 GAPDH PDHB PEX11B FCGBP MAGED2 AHNAK SCP2 NOP2 RAC1 PDPR COPA PUF60 NUDCD3 SH3PXD2B TLN1 EIF4G1 ZFYVE19 ANKRD17 EIF3D AHNAK2 HDGF

1.56e-0513672012232687490
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

USP34 PDHB ASH1L ADARB1 DCAF5 MAPK8IP3 CEP350 NAV3 OSBPL8 ARHGAP21 DOP1B BRWD1 EGLN2 COPA ZNF343 ADAMTS8 MSTO1 EIF4G1 PNMA2 EIF3D PBXIP1

1.97e-0512852012135914814
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

PDHB SELENOH SRPRA TMEM214 PEX11B ZZEF1 MAGED2 OSBPL8 SCP2 NOP2 SEC13 PDPR COPA EGLN1 DTL POR NUDCD3 TMEM209 MTR FUNDC2 ZW10 VPS13B AHNAK2

2.03e-0514962012332877691
Pubmed

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.

ERCC6 PDHB SELENOH MAGED2 POP1 RAC1 SEC13 PUF60 TLN1 EIF4G1 UHRF1

2.54e-054032011135253629
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

SERBP1 GAPDH RPP40 TNRC6B SRPRA AHNAK POP1 OSBPL8 NOP2 SEC13 NEDD4L COPA INTS7 PUF60 DUT DIDO1 TLN1 EIF4G1 EIF3D IK AHNAK2 HDGF

2.63e-0514152012228515276
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

TANC2 SELENOH SRPRA MAGED2 AHNAK SCP2 ARHGAP21 RAC1 RAC3 SEC13 COPA PUF60 ARHGEF5 DUT TLN1 WDR82 EIF3D

2.65e-059162011732203420
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

USP34 TNRC6B SRPRA CEP350 NUFIP2 OSBPL8 CAMSAP1 CHERP EGLN1 DTL NUDCD3 SCAP TMEM209 MTR FUNDC2

2.66e-057332011534672954
Pubmed

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.

TNK1 PIK3C2B ARHGAP21 NEDD4L ARHGEF5 HDAC7

2.94e-05102201615778465
Pubmed

Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus.

TMTC2 NFKBIL1 LTB

3.03e-0511201320662065
Pubmed

TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas.

SERBP1 GAPDH TMEM214 SEC13 PUF60 NUP88 TMEM209

3.09e-05152201728192407
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TNRC6B MAPK8IP3 TNS2 NUDCD3 TLN1 UNC13A

3.28e-05104201610470851
Pubmed

Polymorphisms in the SAA1/2 gene are associated with carotid intima media thickness in healthy Han Chinese subjects: the Cardiovascular Risk Survey.

SAA1 SAA2

3.32e-052201221103356
Pubmed

The rate and significance of type 1/type 2 serum amyloid A protein gene polymorphisms in patients with ankylosing spondylitis and amyloidosis.

SAA1 SAA2

3.32e-052201226300108
Pubmed

DNA sequence evidence for polymorphic forms of human serum amyloid A (SAA).

SAA1 SAA2

3.32e-05220123800865
Pubmed

Activation of AMP-activated protein kinase stimulates the nuclear localization of glyceraldehyde 3-phosphate dehydrogenase in human diploid fibroblasts.

GAPDH PRKAB1

3.32e-052201220177150
Pubmed

Multiple developmental roles of Ahnak are suggested by localization to sites of placentation and neural plate fusion in the mouse conceptus.

AHNAK KDR

3.32e-052201214516657
Pubmed

INTRACELLULAR TRANSPORT. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts.

OSBPL5 OSBPL8

3.32e-052201226206935
Pubmed

Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells.

SAA1 SAA2

3.32e-052201226937641
Pubmed

Rac-deficient cerebellar granule neurons die before they migrate to the internal granule layer.

RAC1 RAC3

3.32e-052201236050459
Pubmed

Rac1 and Rac3 have opposite functions in Schwann cells during developmental myelination.

RAC1 RAC3

3.32e-052201233812927
Pubmed

Identification of a Protein Network Driving Neuritogenesis of MGE-Derived GABAergic Interneurons.

RAC1 RAC3

3.32e-052201228066185
Pubmed

Influence of Serum Amyloid A (SAA1) and SAA2 gene polymorphisms on renal amyloidosis, and on SAA/C-reactive protein values in patients with familial mediterranean fever in the Turkish population.

SAA1 SAA2

3.32e-052201215170927
Pubmed

Acute-phase, but not constitutive serum amyloid A (SAA) is chemotactic for cultured human aortic smooth muscle cells.

SAA1 SAA2

3.32e-052201212557751
Pubmed

Serum amyloid alpha 1-2 are not required for liver inflammation in the 4T1 murine breast cancer model.

SAA1 SAA2

3.32e-052201236817472
Pubmed

Association of genetic variation in serum amyloid-A with cardiovascular disease and interactions with IL6, IL1RN, IL1beta and TNF genes in the Cardiovascular Health Study.

SAA1 SAA2

3.32e-052201219729864
Pubmed

CALM/AF10-positive leukemias show upregulation of genes involved in chromatin assembly and DNA repair processes and of genes adjacent to the breakpoint at 10p12.

PICALM MLLT10

3.32e-052201222064352
Pubmed

No evidence for a role of adipose tissue-derived serum amyloid a in the development of insulin resistance or obesity-related inflammation in hSAA1(+/-) transgenic mice.

SAA1 SAA2

3.32e-052201223967285
Pubmed

Diversity and complexity of the mouse Saa1 and Saa2 genes.

SAA1 SAA2

3.32e-052201224521869
Pubmed

Distinct modes of endocytotic presynaptic membrane and protein uptake at the calyx of Held terminal of rats and mice.

SYT2 UNC13A

3.32e-052201227154627
Pubmed

Heterogeneity of human serum amyloid A protein. Five different variants from one individual demonstrated by cDNA sequence analysis.

SAA1 SAA2

3.32e-05220121971508
Pubmed

Serum amyloid A induces calcium mobilization and chemotaxis of human monocytes by activating a pertussis toxin-sensitive signaling pathway.

SAA1 SAA2

3.32e-05220127561109
Pubmed

Dispensable role of Rac1 and Rac3 after cochlear hair cell specification.

RAC1 RAC3

3.32e-052201237204479
Pubmed

Cellular oxygen sensing: Importins and exportins are mediators of intracellular localisation of prolyl-4-hydroxylases PHD1 and PHD2.

EGLN2 EGLN1

3.32e-052201219631610
Pubmed

Rac1 and Rac3 GTPases differently influence the morphological maturation of dendritic spines in hippocampal neurons.

RAC1 RAC3

3.32e-052201231369617
Pubmed

Human serum amyloid A. Three hepatic mRNAs and the corresponding proteins in one person.

SAA1 SAA2

3.32e-05220123183061
Pubmed

Transcriptional regulation of ependymal cell maturation within the postnatal brain.

NFIX FOXJ1

3.32e-052201229452604
Pubmed

Complete primary structures of two major murine serum amyloid A proteins deduced from cDNA sequences.

SAA1 SAA2

3.32e-05220123857624
Pubmed

E3 ubiquitin-protein ligase 2 inhibits cell proliferation, migration, and invasion of non-small cell lung cancer through ubiquitination of Notch1.

NOTCH1 MIB2

3.32e-052201234971948
Pubmed

Oxysterol-binding protein related-proteins (ORPs) 5 and 8 regulate calcium signaling at specific cell compartments.

OSBPL5 OSBPL8

3.32e-052201229748134
Pubmed

The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.

AHNAK AHNAK2

3.32e-052201215007166
Pubmed

Serum amyloid A protein induces production of matrix metalloproteinases by human synovial fibroblasts.

SAA1 SAA2

3.32e-05220129605178
Pubmed

ORP5/ORP8 localize to endoplasmic reticulum-mitochondria contacts and are involved in mitochondrial function.

OSBPL5 OSBPL8

3.32e-052201227113756
Pubmed

1,2,4-Triazolo-[1,5-a]pyridine HIF Prolylhydroxylase Domain-1 (PHD-1) Inhibitors With a Novel Monodentate Binding Interaction.

EGLN2 EGLN1

3.32e-052201228594552
Pubmed

Inhibition of Rac1 GTPase downregulates vascular endothelial growth factor receptor-2 expression by suppressing Sp1-dependent DNA binding in human endothelial cells.

KDR RAC1

3.32e-052201219469899
Pubmed

Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunity.

SAA1 SAA2

3.32e-052201232572240
Pubmed

Notch Downregulation and Extramedullary Erythrocytosis in Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2-Deficient Mice.

NOTCH1 EGLN1

3.32e-052201227821476
Pubmed

Endothelial prolyl hydroxylase 2 is necessary for angiotensin II-mediated renal fibrosis and injury.

EGLN2 EGLN1

3.32e-052201232715763
Pubmed

The clathrin-binding domain of CALM-AF10 alters the phenotype of myeloid neoplasms in mice.

PICALM MLLT10

3.32e-052201221706055
Pubmed

Effect of serum amyloid A on selected in vitro functions of isolated human neutrophils.

SAA1 SAA2

3.32e-05220129823935
Pubmed

AA amyloidosis-resistant CE/J mice have Saa1 and Saa2 genes that encode an identical SAA isoform.

SAA1 SAA2

3.32e-052201224228751
Pubmed

The frequencies of the serum amyloid A2 alleles in healthy (Turkish, Azerbaijan and Kazakh) populations.

SAA1 SAA2

3.32e-052201216152805
Pubmed

Differential glucocorticoid enhancement of the cytokine-driven transcriptional activation of the human acute phase serum amyloid A genes, SAA1 and SAA2.

SAA1 SAA2

3.32e-052201212077270
Pubmed

Regulation of the human acute phase serum amyloid A genes by tumour necrosis factor-alpha, interleukin-6 and glucocorticoids in hepatic and epithelial cell lines.

SAA1 SAA2

3.32e-052201214871291
Pubmed

Isolation and purification of two major serum amyloid A isotypes SAA1 and SAA2 from the acute phase plasma of mice.

SAA1 SAA2

3.32e-05220129518179
Pubmed

Targeting VEGF-A/VEGFR2 Y949 Signaling-Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension.

KDR RAC1

3.32e-052201236384284
Pubmed

Rac1 and Rac3 GTPases regulate the development of hilar mossy cells by affecting the migration of their precursors to the hilus.

RAC1 RAC3

3.32e-052201221949760
Pubmed

Phosphoinositide 3-Kinase C2beta regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms.

PIK3C2B RAC1

3.32e-052201216775008
Pubmed

Alternative splicing in wild-type AF10 and CALM cDNAs and in AF10-CALM and CALM-AF10 fusion cDNAs produced by the t(10;11)(p13-14;q14-q21) suggests a potential role for truncated AF10 polypeptides.

PICALM MLLT10

3.32e-05220129737689
Pubmed

Structural prerequisites for serum amyloid A fibril formation.

SAA1 SAA2

3.32e-05220128376413
InteractionYWHAG interactions

TANC2 TNK1 SERBP1 GBF1 GAPDH CEP350 PIK3C2B NFATC3 NUFIP2 OSBPL8 MAP3K9 KDR CAMSAP1 ARHGAP21 RAC1 RAC3 NEDD4L PUF60 ARHGEF5 DTL SH2D3C TNS2 RAB11FIP1 HDAC7 FAM171A2 EIF4G1 ANKRD17 PPIP5K1 PPP1R12C AHNAK2

4.44e-06124819730int:YWHAG
InteractionSFN interactions

TANC2 TNK1 SERBP1 GBF1 CEP350 PIK3C2B NFATC3 CAMSAP1 ARHGAP21 NEDD4L ARHGEF5 DTL TEX14 RAB11FIP1 HDAC7 FAM171A2 EIF4G1 ZFYVE19 ANKRD17 PPP1R12C AHNAK2

4.51e-0669219721int:SFN
InteractionTOP3B interactions

TANC2 USP34 GBF1 KMT2B TNRC6B FHIP1B ZZEF1 TNFRSF21 MAPK8IP3 PIK3C2B AHNAK NUFIP2 OSBPL5 CAMSAP1 TSR3 NOP2 ARHGAP21 NOTCH1 RHBDF1 PUF60 MIB2 MLLT10 TEP1 HDAC7 KCNH3 SH3PXD2B CELSR1 SCAP TLN1 EIF4G1 PNMA2 ANKRD17 AHNAK2

5.97e-06147019733int:TOP3B
InteractionH3C1 interactions

ERCC6 KMT2B GAPDH ASH1L ZZEF1 AHNAK POP1 NAV3 UNG CAMSAP1 NOP2 RAC1 CHERP DYNC2H1 EGLN1 DNAH2 DIDO1 MSL1 EIF4G1 UHRF1 IK L3MBTL3 HDGF

2.56e-0590119723int:H3C1
InteractionYWHAH interactions

TANC2 TNK1 SERBP1 GBF1 CEP350 PIK3C2B NFATC3 AHNAK OSBPL5 OSBPL8 MAP3K9 CAMSAP1 ARHGAP21 DOP1B NEDD4L ARHGEF5 DTL TNS2 RAB11FIP1 HDAC7 SH3PXD2B FAM171A2 EIF4G1 ANKRD17 PPP1R12C AHNAK2

2.84e-05110219726int:YWHAH
Cytoband11p15.1-p14

SAA2 SAA4

5.71e-053201211p15.1-p14
GeneFamilyWD repeat domain containing

EML6 DCAF5 EML5 SEC13 BRWD1 COPA DTL TEP1 SCAP WDR82

9.86e-0626212010362
GeneFamilyWD repeat domain containing|DDB1 and CUL4 associated factors

DCAF5 BRWD1 DTL

2.16e-04181203498
GeneFamilyPHD finger proteins

KMT2B ASH1L DIDO1 MLLT10 UHRF1

3.32e-0490120588
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

HECW1 NEDD4L RAB11FIP1

1.74e-03361203823
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

USP34 GAPDH ASH1L TNRC6B SRPRA APOBR ADARB1 PICALM DCAF5 ARID5A CEP350 NFATC3 AHNAK NUFIP2 OSBPL8 NOTCH1 BRWD1 SH2D3C TLN1 MTR CD69 WDR82 LTB ASXL2 IK FYB1 PBXIP1 VPS13B

9.07e-06149219928M40023
CoexpressionGSE3920_UNTREATED_VS_IFNG_TREATED_FIBROBLAST_DN

FHIP1B ADARB1 SAA2 EML5 SCP2 NEDD4L RAB11FIP1 LTB PBXIP1

9.76e-061791999M6689
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAPDH NFIX NOTCH1 FOXJ1 THSD7A GRIK3 CELSR1 TLN1 PBXIP1 PPP1R12C

1.37e-0818620110bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCellPBMC-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

PEX11B APOBR ZNF469 COPA DIDO1 PRKAB1 ANKRD17 WDR82 AHNAK2

2.82e-07196201909d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPP40 ARID5A POP1 ADGRE4P DUT UHRF1 LTB AHNAK2

1.19e-06172201876c06a968d3333441eed103abef1e636a1c3e7a1
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SAA1 SAA2 SAA4 FCGBP EHF KDR NEDD4L CELSR1

1.47e-0617720180f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SAA1 SAA2 SAA4 FCGBP EHF KDR NEDD4L CELSR1

1.47e-061772018779ba86f53650772755b52460be03f18bb204e55
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

FZD4 PIK3C2B KDR SH2D3C HDAC7 USHBP1 MMRN2 UHRF1

1.60e-061792018d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TANC2 PASK PRDM11 AGER OSBPL5 RAC3 SAMD1 TEP1

1.74e-061812018f6629fa71bb94405f523f63a9264cacf6d15c5f4
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAPDH NFIX NOTCH1 FOXJ1 THSD7A GRIK3 CELSR1 PBXIP1

2.40e-061892018965e0e388251e7318f8b463816dc96ccb4658677
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCH1 FZD4 AHNAK KDR SH2D3C RAB11FIP1 USHBP1 MMRN2

2.70e-0619220189ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCH1 FZD4 AHNAK KDR SH2D3C RAB11FIP1 USHBP1 MMRN2

2.70e-061922018a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GCH1 FZD4 AHNAK KDR SH2D3C RAB11FIP1 USHBP1 MMRN2

2.70e-06192201866defad13bd8e79319741e43ddb056841710b1d7
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-2_Progenitor|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PDHB DACT2 AGER EHF SCP2 RAC3 FOXJ1 LAMC2

3.39e-061982018f006d68e6c51923be7772eea118546a5762e8a5e
ToppCellInfluenza-Influenza_Severe-Lymphocyte-T/NK-CD4+_T_naive|Influenza_Severe / Disease, condition lineage and cell class

ARID5A PASK FCGBP UNG ARHGEF5 NUDCD3 CD69 LTB

3.66e-0620020180382f8fc27d18003761725e714beb6b3f3150057
ToppCellSigmoid-(1)_T_cell-(18)_cycling_gd_T|Sigmoid / shred on region, Cell_type, and subtype

GBF1 APOBR DCAF5 SAMD1 FMO5 RPH3AL DTL UHRF1

3.66e-0620020186e367abd1a4b87e20eb9095b8337723163e8bbae
ToppCellSigmoid-T_cell-cycling_gd_T|Sigmoid / Region, Cell class and subclass

GBF1 APOBR DCAF5 SAMD1 FMO5 RPH3AL DTL UHRF1

3.66e-0620020189769185abae084ffac36420c749625e679b70ca8
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

USP34 ASH1L KDR NOTCH1 BRWD1 DTL HDAC7 USHBP1

3.66e-062002018dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

INSRR DACT2 EML5 MAP3K9 GRIK3 SYT2 TEX14

5.25e-0614920176e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SEMA6D PIK3C2B KDR NOTCH1 SH2D3C HDAC7 USHBP1

1.45e-051742017b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RPP40 MAPK8IP3 PIK3C2B TECPR2 MAP3K9 DIDO1 PPIP5K1

1.74e-0517920175be883d7d0be3180bb9844e4a757f0dd247294e4
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHGA PIK3C2B AHNAK KDR HDAC7 DMRT2 USHBP1

1.80e-051802017dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LACTBL1 PASK DTL DUT KCNH3 UHRF1 CD69

1.80e-05180201787347af8f28cf7c486c19f3f98c0afb022c323b5
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHGA PIK3C2B AHNAK KDR HDAC7 DMRT2 USHBP1

1.80e-051802017423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAV3 KDR LAMC2 SYPL2 MMRN2 CD69 LTB

2.07e-05184201797e97de52daaff8840f4ee76a94ba5e3f79de7ce
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMTC2 CEP350 PIK3C2B AHNAK KDR USHBP1 MMRN2

2.22e-0518620170ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-6|TCGA-Lung / Sample_Type by Project: Shred V9

HMCN2 ADGRE4P SH2D3C PKD2L1 ADAMTS8 USHBP1

2.33e-051262016b49b15ba1458488f98d54e87100257a12ee34076
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

IGFN1 HMCN2 SH2D3C HDAC7 USHBP1 MMRN2 CD69

2.38e-051882017c90669b51e1902fe7726555290c91c92a911df83
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EML6 TMTC2 ITPK1 EHF RPH3AL THSD7A MTR

2.46e-051892017fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3C2B NAV3 KDR SH2D3C FAM171A2 USHBP1 MMRN2

2.46e-05189201730dc1725d43a60017fb12d706f1f85a33de4947e
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|343B / Donor, Lineage, Cell class and subclass (all cells)

SAA1 SAA2 SAA4 FCGBP EHF STRA6 NEDD4L

2.46e-051892017a8246acf31f02c85421268245afb651aa8788f14
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SAA1 SAA2 SAA4 FCGBP EHF STRA6 NEDD4L

2.46e-051892017b06471b1bebb990d5146bddfb8002401c6b099a0
ToppCellfacs-Heart-RA-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3C2B NAV3 KDR SH2D3C FAM171A2 USHBP1 MMRN2

2.46e-0518920171be5067c1e45af7d09c1fd6955952cb9e031a3a0
ToppCellfacs-Heart-RV-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 PIK3C2B KDR NOTCH1 SH2D3C USHBP1 MMRN2

2.55e-05190201789d1d686cc683206534e2157554d7d0df5d53497
ToppCellfacs-Heart-RV-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 PIK3C2B KDR NOTCH1 SH2D3C USHBP1 MMRN2

2.55e-05190201765ba6c4f4a2905c0bf4ff99518ae49e3dfd5e640
ToppCellfacs-Heart-RV-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD4 PIK3C2B KDR NOTCH1 SH2D3C USHBP1 MMRN2

2.63e-05191201784ebb9f8e975acc88aa600c08a8aa791256948a6
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SAA1 SAA2 SAA4 FCGBP NFIX EHF KDR

2.72e-051922017c227ab1914191e839fc39c9adc2080026d4b04fc
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SAA1 SAA2 SAA4 FCGBP NFIX EHF KDR

2.72e-051922017bf187a57a559ab732bb815892af45ca922966ac6
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SAA1 SAA2 SAA4 FCGBP NFIX EHF KDR

2.72e-051922017f573b2d205bd4d053a548af3fe3ff9de7be0cd2b
ToppCellT/NK_cells-Regulatory_T_cell|T/NK_cells / Lineage and Cell class

GAPDH PASK AHNAK CD69 LTB FYB1 PBXIP1

2.91e-05194201722843d03366ead435a0cb35092d6f734c225024c
ToppCell15-Airway-Epithelial|Airway / Age, Tissue, Lineage and Cell class

EHF FOXJ1 NEDD4L RGL3 LAMC2 RAB11FIP1 CELSR1

3.01e-051952017cd0af7e260e4f0c5a9ecdfa93619f37b2a9308a5
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 CHGA PICALM SEMA6D NAV3 TLN1 PRKAB1

3.01e-051952017a1478021a3ed0e779716393124ca2a7770c433b7
ToppCellfacs-Heart-RA-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3C2B KDR NOTCH1 SH2D3C HDAC7 USHBP1 MMRN2

3.01e-05195201730c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FZD4 PIK3C2B KDR NOTCH1 THSD7A USHBP1 MMRN2

3.11e-051962017ae46d4b00be92e64e46252dcc156161b171eded4
ToppCellcellseq2|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SAA1 SAA2 SAA4 FCGBP EHF IGLC1 GALNT4

3.11e-051962017d9e1b8386817a668eca90288b6d0e20be4138bf8
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TNFRSF21 NOP2 MIB2 TEP1 ZNF764 ZNF669

3.29e-0513420160e3f37ef041b751ed45060b5ce39385a2731370b
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FZD4 PIK3C2B KDR NOTCH1 THSD7A USHBP1 MMRN2

3.42e-051992017b15304d3d3f6c254969b54a61bee3d9f368840b2
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FZD4 KDR NOTCH1 THSD7A HDAC7 USHBP1 MMRN2

3.42e-051992017f0bf75bfae7b288ecb6801be458b03ebd0108ea7
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-2_Progenitor-Progenitor_AT1-AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PDHB DACT2 AGER RAC3 FOXJ1 LAMC2 PRKAB1

3.42e-051992017329c381404d4972871142dd7f7ee78fbcc365aa1
ToppCellBiopsy_IPF-Endothelial-Endothelial_cells|Biopsy_IPF / Sample group, Lineage and Cell type

FZD4 KDR THSD7A SH2D3C TNS2 USHBP1 MMRN2

3.53e-05200201739b4faad5700b3108f851f0df7fea3d298514465
ToppCellBiopsy_IPF-Endothelial|Biopsy_IPF / Sample group, Lineage and Cell type

FZD4 KDR THSD7A SH2D3C TNS2 USHBP1 MMRN2

3.53e-0520020177ccd3b617838b39da814278dc0e12384013401ce
ToppCellBac-SEP-Lymphocyte-T_NK-CD8_Naive|Bac-SEP / Disease, Lineage and Cell Type

TNK1 PASK HMCN2 ZNF101 MMRN2 LTB

4.93e-051442016fdcf84e8b5fdc0730f243919f9cc30492e24dd75
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAA1 SAA2 FCGBP AHNAK DOP1B TNS2

5.74e-051482016f58804d24fe524b42b5090c8658050ea4b14793e
ToppCellE16.5-samps|World / Age Group, Lineage, Cell class and subclass

SERBP1 SELENOH MAGED2 DTL DUT UHRF1

5.96e-051492016e94d075f68c1c70c89fab50b1b765b5dda650d09
ToppCellCOVID-19_Severe-B_cell|World / disease group, cell group and cell class

CALR3 HCG22 SAA2 PIK3C2B CD69 MAEL

5.96e-0514920169a9fcbf7e8a6811958f3fd2d36315e19ab2b1127
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

VSX1 APOBR AGER ENOSF1 MAEL UNC13A

6.90e-0515320164eb9c2d7e4b95d44198fc87dc115a08ef0153e26
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

VSX1 APOBR AGER ENOSF1 MAEL UNC13A

6.90e-05153201626b5b45c117d155b028d298a0b93e16d343dca97
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

VSX1 APOBR AGER ENOSF1 MAEL UNC13A

6.90e-0515320160f12e38f2cbf69a520764289b0aa4dedc645f714
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|390C / Donor, Lineage, Cell class and subclass (all cells)

PASK CD69 LTB CSKMT FYB1 PBXIP1

8.24e-051582016ad0e2371c0bc6e53d22518aa3a401cddcde3759f
ToppCellPosterior_cortex|World / BrainAtlas - Mouse McCarroll V32

IGFN1 HECW1 NFIX DTL LAMC2 KCNH3

8.54e-05159201618e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GCH1 STRA6 RPH3AL RAB11FIP1 USHBP1 MMRN2

8.84e-05160201604714d0b9bad4c11fa193ed168e2d84a4df39e2e
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 EML6 SEMA6D EHF ADGRE4P RAC3

8.84e-0516020160544bc465af208da448858d6e174ff56f2e08a46
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHGA SAA2 SAA4 STRA6 PMEL UNC13A

9.79e-0516320161eec7f5e5fed05fa21d3f81db588f10605f08ea7
ToppCellSevere-Lymphoid-NK-CCR7+_T|Severe / Condition, Lineage, Cell class and cell subclass

PRDM11 IGHV3-7 ZNF343 KCNH3 LTB PBXIP1

9.79e-0516320168f0d8c124f1569a5a6bc1db7581989f24d63cca3
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GCH1 AHNAK KDR RAB11FIP1 USHBP1 MMRN2

1.01e-0416420166a41a159134e605b80d5e731f9ed5bc803bb531b
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GCH1 AHNAK KDR RAB11FIP1 USHBP1 MMRN2

1.01e-041642016ec68954fc09b6850273b5e59caa6b09d02151097
ToppCell343B-Lymphocytic-ILC|343B / Donor, Lineage, Cell class and subclass (all cells)

ADARB1 ZNF101 CD69 WDR82 CSKMT L3MBTL3

1.08e-041662016a54377c703efff42d2cc1a8fdb610facc58053dd
ToppCell356C-Epithelial_cells-Epithelial-D_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

ARID5A AGER NEDD4L ARHGEF5 LAMC2 UTP14C

1.08e-0416620162e4cb4056e6b0c43290a5588ff525f5f05b8beee
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GCH1 AHNAK KDR RAB11FIP1 USHBP1 MMRN2

1.08e-04166201627af6c906cff1d40d134f0386db7708869691121
ToppCell356C-Epithelial_cells-Epithelial-D_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

ARID5A AGER NEDD4L ARHGEF5 LAMC2 UTP14C

1.08e-041662016eb8d972326a734549675307e411fc795af66da70
ToppCell368C-Myeloid-Dendritic-pDC|368C / Donor, Lineage, Cell class and subclass (all cells)

GBF1 MYOM1 ZNF469 RAC3 DOP1B CHERP

1.12e-0416720161e2fc1637769405a61f4c7e44945712a1888a299
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FZD4 PASK AHNAK OSBPL8 ANKRD17 LTB

1.12e-041672016ced6ed9b412739c6ced622523347c10295edbf53
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNK1 PASK AHNAK INTS7 MTR PPIP5K1

1.15e-0416820162e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCellfacs-Heart-LV-24m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV3 KDR SH2D3C ODF4 USHBP1 MMRN2

1.19e-04169201639d627763abd57e53edb1169832b47cfb3e8c274
ToppCellfacs-Heart-LV-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV3 KDR SH2D3C ODF4 USHBP1 MMRN2

1.19e-0416920166a31a940a8474fb087d8fe7193a6974a72e0a014
ToppCellfacs-Heart-LV-24m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV3 KDR SH2D3C ODF4 USHBP1 MMRN2

1.19e-041692016b85927a256790402e9fc12ebcadd83e4e2afd2ce
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Uncommitted_AE_cell|E16.5-samps / Age Group, Lineage, Cell class and subclass

DACT2 FCGBP AGER MAP3K9 LAMC2 CELSR1

1.23e-0417020165a64e05c263df915085988d881808221e2c0f2e2
ToppCellnormal-na-Lymphocytic_T-T4_em-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

AHNAK OSBPL8 CD69 LTB FYB1 PBXIP1

1.27e-04171201661318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCellfacs-GAT-Fat-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARID5A CELSR1 CD69 MAEL LTB FYB1

1.31e-041722016a9f0ccaca0d83bfec79e3251e346a165c34c242b
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR179 PASK EML5 KDR HDAC7 MMRN2

1.36e-04173201666488d01e03264fb193285470901c9c4182fbae8
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SAA1 SAA2 SAA4 FOXJ1 DYNC2H1 DNAH2

1.36e-041732016c3762655caa79ac4879876f470d32578a3c93b01
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACT2 AGER RAC3 LAMC2 RAB11FIP1 CELSR1

1.40e-041742016d0e3d15731de6c19c232e3aa492c39d8151cf4ed
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOBR ADGRE4P RAC3 OGFRL1 TEP1 FYB1

1.40e-041742016b487c5c46f074a69b9526a2c72daf218f66aa44b
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOBR ADGRE4P RAC3 OGFRL1 TEP1 FYB1

1.40e-0417420163533a47885af453d97739e5576e989d93d31be32
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PASK MMRN2 CD69 LTB FYB1 PBXIP1

1.44e-041752016f456d8d958b71f7a942b718605712593d9de1bfd
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM214 PRDM11 FCGBP NEDD4L RGL3 LAMC2

1.44e-041752016dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCellfacs-Heart-LV|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHGA NAV3 KDR USHBP1 MMRN2 CD69

1.49e-041762016483e36d9bb7268bf179e69a65e1a0be099035162
ToppCellfacs-Skin-nan-18m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOBR SEMA6D RGL3 CD69 LTB FYB1

1.54e-0417720166e45e1a5a894ca2e4ebc5cdb17fdf79e9e188185
ToppCellfacs-Skin-nan-18m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOBR SEMA6D RGL3 CD69 LTB FYB1

1.54e-04177201617065d37fd41f04f67282bee00365daa185e8355
ToppCellfacs-Skin-nan-18m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOBR SEMA6D RGL3 CD69 LTB FYB1

1.54e-0417720169ff3a77c5c62c8a950c46ca22cd7bde425b84c9a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC2 TMCO4 RPH3AL THSD7A NEDD4L DMRT2

1.54e-041772016f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 UNG DTL DUT SH3PXD2B UHRF1

1.58e-041782016de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADARB1 KDR SH2D3C HDAC7 USHBP1 MMRN2

1.58e-041782016ba2f0585626988b511046630bc16be5c5fec3fb2
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|390C / Donor, Lineage, Cell class and subclass (all cells)

CHGA SAA1 SAA2 SAA4 EHF GRIK3

1.58e-041782016fce60ce6b662f1bdaa3b4da43800c6c22fe89533
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|390C / Donor, Lineage, Cell class and subclass (all cells)

CHGA SAA1 SAA2 SAA4 EHF GRIK3

1.58e-041782016b19c906e067b07eadfd68934d9330b447e24c708
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-Activated_CD4_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARID5A PASK CD69 LTB FYB1 PBXIP1

1.63e-04179201602218c048e4dec0c0a3d63d2abb4feb4c3e82697
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SAA1 SAA2 SAA4 FOXJ1 DYNC2H1 DNAH2

1.68e-04180201692fb01b91261b3103454924cde56add337b41844
ToppCellP15-Endothelial-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SELENOH PASK DTL DUT UHRF1 HDGF

1.73e-0418120160c5bc1660b8fc1e905ab4230202862de5be46ebd
ToppCellILEUM-non-inflamed-(3)_DC1|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

APOBR EHF NFKBIL1 NOTCH1 SYT2 SLC6A2

1.73e-041812016c9f53720249c8569598cc859e43e35c5f3f8475a
ToppCellP15-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SELENOH PASK DTL DUT UHRF1 HDGF

1.73e-041812016f83565f09dd971c5cad2704a4a86bca0accd955e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 EML6 TMTC2 EHF THSD7A MTR

1.84e-041832016b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GBF1 ERCC6 MAP3K9 ZNF101 RAB11FIP1 ZNF764

1.84e-041832016a492b3827d2c368d33a7a5118748beaf4d7f6797
DrugHelveticoside [630-64-8]; Down 200; 7.4uM; HL60; HT_HG-U133A

RPP40 PEX11B TNFRSF21 CLCN3 MAGED2 PIK3C2B POP1 CAMSAP1 TSR3 ZW10

4.67e-06186194102192_DN
DrugAlbendazole [54965-21-8]; Down 200; 15uM; HL60; HG-U133A

KMT2B TNFRSF21 PIK3C2B TSR3 NOTCH1 ENOSF1 ZNF764 EIF4G1 CD69 WDR82

6.78e-06194194101547_DN
DrugPicotamide monohydrate [80530-63-8]; Down 200; 10.2uM; PC3; HT_HG-U133A

KMT2B PICALM MAPK8IP3 CEP350 CLCN3 BRWD1 DIDO1 MLLT10 HDAC7 PBXIP1

7.76e-06197194102070_DN
DrugMifepristone [84371-65-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A

VSX1 APOBR PRDM11 TECPR2 AHNAK DYNC2H1 GPR37 LAMC2 ADAMTS8 SYT2

8.11e-06198194103185_UP
DrugTiclopidine hydrochloride [53885-35-1]; Down 200; 13.4uM; PC3; HT_HG-U133A

KMT2B MAPK8IP3 NAV3 BRWD1 NEDD4L COPA NUDCD3 MLLT10 TMEM209 PBXIP1

8.11e-06198194104074_DN
DrugThr-Met

SAA1 SAA2 SAA4 MTR

1.12e-05171944CID006427022
Diseasechromogranin-A measurement

CHGA ITPK1

1.27e-0431932EFO_0022021
Diseaseautosomal dominant intellectual developmental disorder 48 (implicated_via_orthology)

RAC1 RAC3

1.27e-0431932DOID:0080235 (implicated_via_orthology)
DiseaseDystonia, Limb

KMT2B GCH1 SCP2

1.75e-04171933C0751093
DiseaseDystonia, Diurnal

KMT2B GCH1 SCP2

1.75e-04171933C0393610
DiseaseDystonia, Paroxysmal

KMT2B GCH1 SCP2

2.09e-04181933C0393588
DiseasePolyarthritis

COPA CD69

4.20e-0451932C0162323
DiseaseCraniofacial Abnormalities

ERCC6 VSX1 FZD4 STRA6 NOTCH1 SH3PXD2B

5.84e-041561936C0376634
Diseaseserum amyloid A protein measurement

SAA1 SAA2

6.27e-0461932EFO_0004728
Diseasechronic obstructive pulmonary disease, CC16 measurement

AHNAK EHF

6.27e-0461932EFO_0000341, EFO_0005080
DiseaseAbnormal muscle tone

MAPK8IP3 RAC3

6.27e-0461932C0852413
DiseaseArthritis

COPA CD69

6.27e-0461932C0003864
DiseasePolysyndactyly

FZD4 NEDD4L

8.75e-0471932C0265553
DiseaseR-6-hydroxywarfarin measurement

SOWAHC SEMA6D SELENOO DNAH2 MTR

9.38e-041141935EFO_0803327
DiseaseSyndactyly

FZD4 NEDD4L

1.16e-0381932C0039075
Diseasehypertension (is_implicated_in)

GCH1 CHGA KDR SLC6A2 MTR

1.22e-031211935DOID:10763 (is_implicated_in)
Diseasehemangiopericytoma (is_marker_for)

KDR NOTCH1

1.49e-0391932DOID:264 (is_marker_for)
Diseasecysteine measurement

NAV3 GRIK3

1.49e-0391932EFO_0021000
DiseaseLeukoencephalopathy

SCP2 MTR

2.25e-03111932C0270612
DiseaseMicrophthalmos

ERCC6 STRA6

2.25e-03111932C0026010
Diseaseinsulin sensitivity measurement, response to polyunsaturated fatty acid supplementation

TNRC6B RPH3AL

2.25e-03111932EFO_0004471, EFO_0009131
DiseaseDystonia

ERCC6 KMT2B GCH1 SCP2

2.48e-03861934C0013421
DiseaseCleft palate, isolated

FZD4 NEDD4L MTR

2.62e-03421933C1837218
Diseaseretinopathy of prematurity (biomarker_via_orthology)

KDR NOTCH1

2.69e-03121932DOID:13025 (biomarker_via_orthology)
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

PDHB AHNAK NAV3 KDR MLLT10

2.95e-031481935C0279702
Diseasetuberculosis

NALCN POP1 NAV3 THSD7A DYNC2H1 VPS13B

3.07e-032161936MONDO_0018076
Diseasekynurenic acid measurement

SEMA6D THSD7A

3.17e-03131932EFO_0010506
DiseaseConnective Tissue Diseases

ZNF469 NOTCH1

3.17e-03131932C0009782
Diseaselate-onset Alzheimers disease

PICALM TMCO4 CCDC112 AHNAK SELENOO RHBDF1 FAM171A2

3.22e-032921937EFO_1001870
Diseasedystonia (is_implicated_in)

KMT2B GCH1

3.68e-03141932DOID:543 (is_implicated_in)
DiseaseChildhood Ataxia with Central Nervous System Hypomyelinization

SCP2 MTR

3.68e-03141932C1858991
DiseaseAlzheimer disease, APOE carrier status

NOTCH1 THSD7A GRIK3 L3MBTL3

3.97e-03981934EFO_0007659, MONDO_0004975
Diseasehepcidin:transferrin saturation ratio

PDHB EML6

4.23e-03151932EFO_0007902
DiseaseAdenoid Cystic Carcinoma

INSRR NOTCH1 DTL UHRF1

4.27e-031001934C0010606
Diseasepulmonary fibrosis (biomarker_via_orthology)

GCH1 AGER NOTCH1

4.31e-03501933DOID:3770 (biomarker_via_orthology)
Diseasepreeclampsia, hypertension, pregnancy-induced

RGL3 TNS2

4.81e-03161932EFO_0000668, MONDO_0024664
Diseasebehavioural inhibitory control measurement

PRDM11 STRA6

4.81e-03161932EFO_0008467
Diseaseglucose metabolism measurement, age-related hearing impairment

ZNF469 NAV3 THSD7A

4.81e-03521933EFO_0005782, EFO_0009367
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

INSRR AGER ADAMTS8 MTR

5.07e-031051934DOID:9352 (implicated_via_orthology)
DiseasePrecursor T-Cell Lymphoblastic Leukemia-Lymphoma

PICALM NOTCH1 MLLT10

5.08e-03531933C1961099
Diseaseresponse to cisplatin, platinum measurement

SPATA31E1 ADARB1 INTS7

5.08e-03531933EFO_0010154, GO_0072718
DiseaseEye Abnormalities

VSX1 SH3PXD2B

5.43e-03171932C0015393
DiseaseAcute myeloid leukemia

PICALM MLLT10

5.43e-03171932cv:C0023467
DiseaseLEUKEMIA, ACUTE MYELOID

PICALM MLLT10

5.43e-03171932601626
Diseaseestradiol measurement

EHF ARHGAP21 IGHV3-7 CELSR1

5.98e-031101934EFO_0004697
Diseaseprostate carcinoma

TANC2 TNRC6B TMTC2 ITPK1 CEP350 PIK3C2B EHF OSBPL5 OGFRL1 SH3PXD2B INTS4 L3MBTL3 PBXIP1

6.02e-0389119313EFO_0001663
Diseaseserum amyloid A-1 protein measurement

SAA1 SAA2

6.08e-03181932EFO_0008282
DiseaseUterine leiomyoma, estrogen-receptor positive breast cancer

TNRC6B MLLT10

6.08e-03181932EFO_1000649, HP_0000131
Diseasebehavior or behavioral disorder measurement, personality trait

BRWD1 INTS7

6.08e-03181932EFO_0004365, EFO_0004782
Diseaseserum IgG measurement

PDHB UNC13A

6.08e-03181932EFO_0004565

Protein segments in the cluster

PeptideGeneStartEntry
AARNVPVGFGESWKK

UNG

86

P13051
NGVVKIPDAKGDDAW

UNC13A

836

Q9UPW8
IDGGQVGRAWDPEKL

USHBP1

576

Q8N6Y0
SRKQVKPGEGWGRSS

nan

31

Q6ZRP5
GKEGLSVKEPQLVWG

ARID5A

376

Q03989
GWGIRTKEPLKAGQF

ASH1L

2156

Q9NR48
GWEERTKKIGPTGSG

CCDC112

411

Q8NEF3
AAPWAGSEKAAKRGP

ASCL5

16

Q7RTU5
DNFGKATWGETKGPE

CALR3

326

Q96L12
KTKRVGASEGNPQWG

BAALC-AS2

11

P0C853
EKWGPEVSDNGGLTL

ADAMTS8

276

Q9UP79
AKEPESWDGGRLGAV

ARHGEF5

376

Q12774
VDIWVSGVKPGFGKQ

ADGRE4P

116

Q86SQ3
AKEPESWDGGRLGAV

ARHGEF35

376

A5YM69
KGSGGEWKGPQVSSA

AHNAK

5591

Q09666
DGVGAEEKWDPARGA

CELSR1

2831

Q9NYQ6
EKPGGDKLSTVGWAS

DTL

396

Q9NZJ0
TVASPKRGQKREEGW

ANKRD17

1706

O75179
DGQPRGAAIAWPEKK

CAMSAP1

451

Q5T5Y3
FHRTSGGEGIWKLKP

ERCC6

1476

Q03468
VPAKPATWEGKQSDG

ASXL2

206

Q76L83
IDESWKGGGPAASLQ

ZFYVE19

266

Q96K21
GRTEAWKVLSPQGGG

AGER

56

Q15109
VDGKPVNLGLWDTAG

RAC3

46

P60763
VDGKPVNLGLWDTAG

RAC1

46

P63000
GEFSSGRKWGDDAPK

INTS4

346

Q96HW7
KDANGIVWKTGPRTT

INTS7

911

Q9NVH2
QRPGKERKSGEAGWG

ODF4

21

Q2M2E3
SAWGGSKGPLDQLEK

SERPIND1

16

P05546
TKNRGGPDRWKETGG

KCNH3

136

Q9ULD8
WKDGVGTLPGSDLKF

L3MBTL3

21

Q96JM7
AGREEHWVGLKKEPG

CD69

136

Q07108
PNEGADGQWKKGFVL

SERBP1

311

Q8NC51
NGVPGSWPEGAKKVR

FHIP1B

636

Q8N612
GLKVVSPWNSEDAKG

PDHB

171

P11177
IWGPPRKEQSEGSKA

OGFRL1

311

Q5TC84
LWAGAAVAKPQAKGQ

PASK

586

Q96RG2
GWPNDVDAGPASLKK

NFIX

311

Q14938
EGWAAPDALLGQVKA

NOTCH1

1636

P46531
PWKAEADAGGTAKLP

ITPK1

371

Q13572
NVGVWASGEGKKVDI

HOGA1

21

Q86XE5
WRAAQGKDPGPSEKQ

MAEL

61

Q96JY0
ADIGPWAKARIQAGA

MAGED2

521

Q9UNF1
SGWRPNEDDAGNGVK

MAPK8IP3

716

Q9UPT6
TNWLRAKEPAGENGG

POR

491

P16435
LKKGWDAEGSPFRGQ

NUDCD3

331

Q8IVD9
RKVEKPGWEAAGPEA

GPR179

1356

Q6PRD1
GKGLEWVANIKQDGS

IGHV3-7

61

P01780
RTPGVWKAEAEDTGK

MMRN2

36

Q9H8L6
PRGWEIKTDQQGKSF

HECW1

1021

Q76N89
SWSKDGVVLQGRGPQ

HMCN2

1196

Q8NDA2
SPARKNGGEWDVEKV

DOP1B

721

Q9Y3R5
TSDGQLRWIGPEKGV

ENOSF1

96

Q7L5Y1
SSDGVWRVKSIPNGK

MSTO1

126

Q9BUK6
WQGGILSGGFEKNPK

PDPR

296

Q8NCN5
DAGGKWKTVSSGLPE

NAV3

956

Q8IVL0
LDKGTWDAVARGGLP

CSKMT

161

A8MUP2
TVGGPWGQSQEKEKG

FYB1

321

O15117
PNKRKGFSEGLWEIE

HDGF

76

P51858
ANSKEGVGLWDIRKP

DCAF5

206

Q96JK2
NGWTGKQKSPDGVHR

KMT2B

1156

Q9UMN6
EGKAVAGAWEKGPRL

LBHD2

21

A0A0U1RRK4
SAIPSEVQGKGGVWK

PNMA2

76

Q9UL42
KNKDGETPGQILGWG

NFKBIL1

131

Q9UBC1
STVGAAGWKGELPKA

DUT

71

P33316
AKEPTPWAGDKGGAA

MSL1

146

Q68DK7
KAGLGAWVEKPTEQD

ADARB1

721

P78563
GWAAPGSAEAQKAEK

RGL3

176

Q3MIN7
KSSDGTWARPVGKVG

PIK3C2B

1491

O00750
TWARPVGKVGGEVKL

PIK3C2B

1496

O00750
GEKDAKVPGTWRDGV

HCG22

26

E2RYF7
DPKSGLWVRNGTGVI

FAM171A2

256

A8MVW0
VGDEAGDKKSPWQRR

FAM171A2

801

A8MVW0
WAVKGPKGEAVGSIT

OSBPL8

221

Q9BZF1
EGLSSPGGWLEAEKK

METTL21C

16

Q5VZV1
GWKAGPEGTSQEIPK

POP1

86

Q99575
QQPGKVTGEDRLGWG

POP1

601

Q99575
KRGNGWVKPGKGSET

FZD4

521

Q9ULV1
GSGGKSQITWDNPKE

DYNC2H1

656

Q8NCM8
AWKADGSPVKAGVET

IGLC1

41

P0CG04
RWKGARGQEPSETLG

GPR37

121

O15354
VLWTGNFGKKNGSDP

LACTBL1

51

A8MY62
WGRETPAKGSEGEQG

DACT2

341

Q5SW24
SVQALKPGASWDLKG

DMRT2

366

Q9Y5R5
KPGASWDLKGARVQD

DMRT2

371

Q9Y5R5
WTPGLGAGEKLVQAA

CCDC175

6

P0C221
GIQDPIKGGDVRDKW

CHERP

866

Q8IWX8
RNPEALAKWAEGKTG

CRY2

341

Q49AN0
DLKAVGGKPAGWQVG

FCGBP

2221

Q9Y6R7
DDLKAVGGKPAGWQV

FCGBP

3421

Q9Y6R7
ADDLKAVGGKPAGWQ

FCGBP

4621

Q9Y6R7
NWKDAGLKNGVPAVG

COPA

986

P53621
KPPADSRALGEWGKA

GALNT4

66

Q8N4A0
DKNPGLIKWEDRSEG

EHF

221

Q9NZC4
QGPGKWDGARKAILT

FMO5

476

P49326
QPFSKGDRLGKVADW

EIF3D

31

O15371
GAVKVAWKADGSPVN

IGLC6

36

P0CF74
GGTQSKGPWEELAKG

CEP350

1046

Q5VT06
SGEKPPAGSEQDGWK

DIDO1

1621

Q9BTC0
KDEPGKGGFWRIDPQ

FOXJ1

186

Q92949
KPQAGEWGQKSRDEE

BRWD1

1151

Q9NSI6
IRGDKITWIEGKEPG

EGLN1

251

Q9GZT9
LVDDGGWNTVPISKG

EIF4G1

1046

Q04637
DGIPGKVAWEASSKN

INSRR

816

P14616
LLGDTVEKIAWQKGG

FPGS

231

Q05932
WLVVGKDDVDNSKPG

GBF1

1346

Q92538
DGWKAVQRNGSPAKL

LAMC2

216

Q13753
SDLGPGTWFKDGVKL

IGFN1

481

Q86VF2
GKERPSKEGGAVKLW

EML5

1621

Q05BV3
ERPTKEGGAVKLWDQ

EML6

1616

Q6ZMW3
SWKGTKPIDLGNGQT

FAH

366

P16930
APKRKWAEDGGDAPS

EGLN2

116

Q96KS0
GNRVDPLSEEGWKQK

HDAC7

861

Q8WUI4
GLEKVGVWSPADGLN

GRIK3

401

Q13003
ARKAPGKGLEWVSGV

IGHV3-16

56

A0A0C4DH30
IQKVGGPSSKWEAVG

DNAH2

1571

Q9P225
GKSGLAPRVDQEKWA

PEX11B

106

O96011
GERGPQSAKERVKEW

SAMD1

366

Q6SPF0
DAAQRGPGGVWAAKL

SAA4

61

P35542
QESWERLSDGGKAGP

SCAP

831

Q12770
GRTWGPGTLGQKELA

MAP3K9

596

P80192
GIFQGAKVVRGPDWE

MIB2

156

Q96AX9
QSVWAVKGPKGESVG

OSBPL5

196

Q9H0X9
LPKRWGKNSEFEGGK

NUP88

136

Q99567
AWNGSAEGPGKVERE

NYAP1

656

Q6ZVC0
PVSWEKNEHGFRKGG

RPP40

321

O75818
RDRKGDKPWKESGGS

RPH3AL

231

Q9UNE2
DKPWKESGGSVEAPR

RPH3AL

236

Q9UNE2
WRKLFGQESGPSAEK

FUNDC2

66

Q9BWH2
GGDNKVTLWKESVDG

SEC13

281

P55735
GQPIEEWRDLQGGEK

SYT2

251

Q8N9I0
WGKGLTDVKGATRPS

SYPL2

171

Q5VXT5
GDAQPRETWGKKIDF

SLC6A2

51

P23975
WKEPAEGGGLSSDRQ

RAB11FIP1

366

Q6WKZ4
VVTPDGHGKNRAKWG

TRIM42

696

Q8IWZ5
RGQNPKTWALTAGKE

TEX14

121

Q8IWB6
RKVGKEWRGPAEGEE

PPP1R12C

626

Q9BZL4
DAAKRGPGGAWAAEV

SAA2

61

P0DJI9
PVGWGVRKKGTETED

TNFRSF21

151

O75509
VVAAGDKWKPPQGTD

PUF60

26

Q9UHX1
KAVGIRTKPGWDEKG

TMCO4

516

Q5TGY1
WKAVRLGNCEPDNGK

THSD7A

576

Q9UPZ6
RSEDEQRWGKGPGQD

UPF3A

381

Q9H1J1
KTVDGPSGKLWRDGR

GAPDH

186

P04406
RPEAKSAQPADGWKG

GCH1

41

P30793
EGDWKVPQGVSKEPG

PRDM11

396

Q9NQV5
GGKKVIQTDEWRNGP

MTR

656

Q99707
ERGWRKQKEGAAAPQ

RHBDF1

321

Q96CC6
ENIPKGLDQEGWTRG

PPP1R32

351

Q7Z5V6
ATGERWELQLKGAGP

SELENOO

166

Q9BVL4
SSKELGSGGNIKPWQ

TANC2

201

Q9HCD6
PRKGGTRWEDVLQKG

SPATA31E1

1276

Q6ZUB1
TRWEDVLQKGKPGAD

SPATA31E1

1281

Q6ZUB1
DSELAKPGEKEGWRN

NLRP7

111

Q8WX94
EGWVGGKAKDPGRKA

SOWAHC

446

Q53LP3
DVNAAGIWEPKKGDV

THAP6

46

Q8TBB0
RGVNLDPLGKWSKTG

NOP2

331

P46087
WRGGQVSLKVSNDGP

PMEL

61

P40967
FKVKDGPGGKEATWV

SCP2

461

P22307
GPGGKEATWVVDVKN

SCP2

466

P22307
DGKTEAPRGAWKILG

STRA6

136

Q9BX79
DAAKRGPGGVWAAEA

SAA1

61

P0DJI8
QARPTVFRWTGGGKE

PRKAB1

76

Q9Y478
KESPGLWGASILKAG

AHNAK2

5426

Q8IVF2
PHKDGALKRTDNGGW

MLLT10

86

P55197
ALEGVLGQGWDSKEK

APOBR

781

Q0VD83
VDREKGLSAEPGWQA

CHGA

211

P10645
KTWAELIIGQAEGPG

CLCN3

191

P51790
DVNWSQPGEKKLTGG

PICALM

561

Q13492
KPGSEDKLAGLWGSD

VSX1

281

Q9NZR4
ENAEGQERGGGSKPW

ZNF343

166

Q6P1L6
GRPLFVAGGQWKDTS

nan

251

Q6ZTK2
GEWGGVGLKPSAKKR

UTP14C

631

Q5TAP6
WNGESGIKVAVLDGK

WDR82

266

Q6UXN9
GKQIKSIDAGPVDAW

WDR61

96

Q9GZS3
CDGSPKSQGVKRGWL

nan

106

Q6ZSN1
LPKGTKSWEEAVAAG

TEP1

1441

Q99973
SEQKGNRVDGSKPIW

NUFIP2

266

Q7Z417
RKKNWGGQEDREPAG

PBXIP1

501

Q96AQ6
AAGKVGDDPAVWQLK

TLN1

2101

Q9Y490
PWGTGKIGENREKAA

SH3PXD2B

826

A1X283
LSDKVPQDGGGWRSA

STYXL2

361

Q5VZP5
SGIKVNPAKAWGNLG

TMTC2

486

Q8N394
PDGSSAELWTGIKKG

SELENOH

86

Q8IZQ5
WEVVKKGRRPGVGAG

TMEM214

11

Q6NUQ4
PQGSWKVGTLFHGKR

TLE7

146

A0A1W2PR48
KGQDGRPQWEVEGKI

NFATC3

636

Q12968
GKKAPRVWELGGCAN

SRPRA

241

P08240
WFRTGIISKKPQGDD

TECPR2

1006

O15040
QGNKKGPLGRWDFDT

IK

471

Q13123
SPEGQELQKLGSGAW

PKD2L1

6

Q9P0L9
GGDFKGRKWDTDLPT

TMEM209

431

Q96SK2
DPWGQEGEAKKDSPG

ZNF469

3226

Q96JG9
GAEAKDWRSGKPVRV

UHRF1

521

Q96T88
ECGGEWRETPRKQKQ

ZNF101

131

Q8IZC7
PGSIDGDRKKANLWD

TNK1

466

Q13470
TSPKWKDGGNGEVVT

VPS13B

3051

Q7Z7G8
GPEGGLRKLDVETWQ

ZZEF1

1071

O43149
KELSENGAPEGDWGK

SH2D3C

526

Q8N5H7
VPDGNRISWDSKKGF

KDR

171

P35968
WPGKSRKAAGDHAKG

USP34

1561

Q70CQ2
GIPKGVRWEVQSGES

SEMA6D

641

Q8NFY4
DKGKRVGGSIRPWKQ

ARHGAP21

946

Q5T5U3
REAGEGWASEAGKPL

TNS2

711

Q63HR2
LKWGGELTPAGRVQA

PPIP5K1

521

Q6PFW1
GSDELKIGEWSGPNQ

TNRC6B

516

Q9UPQ9
RPEGKSDKGTEGWES

TNRC6B

641

Q9UPQ9
GRGAEARAPAEVWKG

TSR3

291

Q9UJK0
SGEEGWLKPAVARLG

ZNF669

11

Q96BR6
GIGGNKPALISWVEE

ZNF764

66

Q96H86
EIGDRWADGKGPLAA

ZW10

736

O43264
DGKAGTWNVELAPKR

ZSCAN23

186

Q3MJ62
PLKGQGLGWETTKEQ

LTB

96

Q06643
DAADAGKPQRKFGQW

NALCN

1656

Q8IZF0
IDGVPGKWREANVKA

MYOM1

976

P52179
GLPSGWEERKDAKGR

NEDD4L

386

Q96PU5