Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentcollagen-containing extracellular matrix

ADAMTS10 PODNL1 IL16 LMAN1 ADAMTS4 LAMA1 LAMA4 HRG USH2A ADAMTSL4

5.95e-065306610GO:0062023
GeneOntologyCellularComponentextracellular matrix

ADAMTS10 PODNL1 IL16 FCGBP LMAN1 ADAMTS4 LAMA1 LAMA4 HRG USH2A ADAMTSL4

5.98e-066566611GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

ADAMTS10 PODNL1 IL16 FCGBP LMAN1 ADAMTS4 LAMA1 LAMA4 HRG USH2A ADAMTSL4

6.15e-066586611GO:0030312
DomainEGF_LAM_2

CELSR1 STAB2 LAMA1 LAMA4 USH2A

6.29e-0830665PS50027
DomainEGF_LAM_1

CELSR1 STAB2 LAMA1 LAMA4 USH2A

6.29e-0830665PS01248
DomainEGF_Lam

CELSR1 STAB2 LAMA1 LAMA4 USH2A

1.41e-0735665SM00180
DomainLaminin_EGF

CELSR1 STAB2 LAMA1 LAMA4 USH2A

2.17e-0738665IPR002049
DomainTF_fork_head_CS_2

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

5.79e-0746665IPR030456
DomainTF_fork_head_CS_1

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

6.46e-0747665IPR018122
DomainFH

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

7.99e-0749665SM00339
DomainFORK_HEAD_1

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

7.99e-0749665PS00657
DomainFORK_HEAD_2

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

7.99e-0749665PS00658
DomainFork_head_dom

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

7.99e-0749665IPR001766
DomainFORK_HEAD_3

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

7.99e-0749665PS50039
DomainForkhead

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

7.99e-0749665PF00250
DomainLaminin_EGF

CELSR1 LAMA1 LAMA4 USH2A

6.86e-0635664PF00053
DomainLAM_G_DOMAIN

CELSR1 LAMA1 LAMA4 USH2A

9.59e-0638664PS50025
DomainLaminin_G_2

CELSR1 LAMA1 LAMA4 USH2A

1.18e-0540664PF02210
DomainLamG

CELSR1 LAMA1 LAMA4 USH2A

1.74e-0544664SM00282
Domain-

CELSR1 LMAN1 LAMA1 LAMA4 USH2A

2.14e-05956652.60.120.200
DomainLaminin_G

CELSR1 LAMA1 LAMA4 USH2A

5.23e-0558664IPR001791
DomainADAM_spacer1

ADAMTS10 ADAMTS4 ADAMTSL4

7.10e-0523663IPR010294
DomainADAM_spacer1

ADAMTS10 ADAMTS4 ADAMTSL4

7.10e-0523663PF05986
Domain-

FOXD4L4 FOXD4L3 FOXD4L6 CDC6 FOXD4L5 FOXD4

1.20e-042186661.10.10.10
DomainLaminin_aI

LAMA1 LAMA4

1.22e-045662IPR009254
DomainLaminin_I

LAMA1 LAMA4

1.22e-045662PF06008
DomainLaminin_II

LAMA1 LAMA4

1.22e-045662PF06009
DomainLaminin_domII

LAMA1 LAMA4

1.22e-045662IPR010307
DomainEGF

CELSR1 STAB2 FCGBP LAMA1 LAMA4 NOTCH3

1.80e-04235666SM00181
DomainWHTH_DNA-bd_dom

FOXD4L4 FOXD4L3 FOXD4L6 CDC6 FOXD4L5 FOXD4

2.11e-04242666IPR011991
DomainGrowth_fac_rcpt_

EPHB3 CELSR1 STAB2 LAMA1 NOTCH3

2.26e-04156665IPR009030
DomainEGF-like_dom

CELSR1 STAB2 FCGBP LAMA1 LAMA4 NOTCH3

2.46e-04249666IPR000742
DomainEGF_1

CELSR1 STAB2 LAMA1 LAMA4 USH2A NOTCH3

2.80e-04255666PS00022
DomainTIL

FCGBP MUC19

7.93e-0412662PF01826
DomainC8

FCGBP MUC19

7.93e-0412662PF08742
DomainUnchr_dom_Cys-rich

FCGBP MUC19

9.36e-0413662IPR014853
DomainC8

FCGBP MUC19

9.36e-0413662SM00832
DomainConA-like_dom

CELSR1 LMAN1 LAMA1 LAMA4 USH2A

1.06e-03219665IPR013320
DomainPLAC

ADAMTS10 ADAMTSL4

1.09e-0314662PF08686
DomainTIL_dom

FCGBP MUC19

1.09e-0314662IPR002919
DomainVWD

FCGBP MUC19

1.43e-0316662SM00216
DomainVWF_type-D

FCGBP MUC19

1.43e-0316662IPR001846
DomainLaminin_N

LAMA1 USH2A

1.43e-0316662IPR008211
DomainLAMININ_NTER

LAMA1 USH2A

1.43e-0316662PS51117
DomainVWFD

FCGBP MUC19

1.43e-0316662PS51233
DomainLaminin_N

LAMA1 USH2A

1.43e-0316662PF00055
DomainVWD

FCGBP MUC19

1.43e-0316662PF00094
DomainLamNT

LAMA1 USH2A

1.43e-0316662SM00136
DomainTSP_1

ADAMTS10 ADAMTS4 ADAMTSL4

1.44e-0363663PF00090
DomainTSP1

ADAMTS10 ADAMTS4 ADAMTSL4

1.57e-0365663SM00209
DomainTSP1_rpt

ADAMTS10 ADAMTS4 ADAMTSL4

1.57e-0365663IPR000884
DomainTSP1

ADAMTS10 ADAMTS4 ADAMTSL4

1.57e-0365663PS50092
DomainVWC_out

FCGBP MUC19

2.02e-0319662SM00215
DomainPLAC

ADAMTS10 ADAMTSL4

2.02e-0319662PS50900
DomainPLAC

ADAMTS10 ADAMTSL4

2.02e-0319662IPR010909
DomainEGF-like_CS

CELSR1 STAB2 LAMA1 LAMA4 NOTCH3

2.29e-03261665IPR013032
Domainfn3

EPHB3 IL12RB1 SPEG USH2A

2.59e-03162664PF00041
DomainPeptidase_M12B_ADAM-TS

ADAMTS10 ADAMTS4

3.23e-0324662IPR013273
DomainIg-like_fold

EPHB3 IL12RB1 NFATC1 IGHA1 SPEG SIRPB2 USH2A ADGRA2

3.33e-03706668IPR013783
DomainFN3

EPHB3 IL12RB1 SPEG USH2A

4.16e-03185664SM00060
DomainHRM

CELSR1 ADGRA2

4.38e-0328662PF02793
DomainFN3

EPHB3 IL12RB1 SPEG USH2A

5.39e-03199664PS50853
DomainFN3_dom

EPHB3 IL12RB1 SPEG USH2A

6.39e-03209664IPR003961
DomainGPS

CELSR1 ADGRA2

6.41e-0334662SM00303
DomainGPS

CELSR1 ADGRA2

6.79e-0335662PF01825
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS10 ADAMTS4 ADAMTSL4 NOTCH3

4.83e-0568424M27303
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS10 ADAMTS4 ADAMTSL4

2.09e-0439423M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS10 ADAMTS4 ADAMTSL4

2.09e-0439423MM15165
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS10 ADAMTS4 MUC19 ADAMTSL4

3.02e-04109424MM15164
Pubmed

Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

1.59e-13669527092474
Pubmed

The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

1.48e-1286958530406
Pubmed

An amphioxus winged helix/forkhead gene, AmphiFoxD: insights into vertebrate neural crest evolution.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

3.32e-12969512412011
Pubmed

A genetic study of the suppressors of the Engrailed-1 cerebellar phenotype.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

3.37e-111369516884697
Pubmed

Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

3.37e-11136957957066
Pubmed

FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines.

FOXD4L4 FOXD4L6 FOXD4L5 FOXD4

7.08e-11569412234674
Pubmed

Six members of the mouse forkhead gene family are developmentally regulated.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

7.84e-11156957689224
Pubmed

Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

7.84e-111569522045912
Pubmed

Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

1.14e-10166958861101
Pubmed

Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

1.14e-101669510208738
Pubmed

Functional equivalency between Otx2 and Otx1 in development of the rostral head.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

3.02e-10196959895322
Pubmed

Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

4.02e-102069512812790
Pubmed

Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

5.26e-10216959449667
Pubmed

Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

6.80e-102269517389379
Pubmed

Otx2 is required to respond to signals from anterior neural ridge for forebrain specification.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

1.09e-092469511820816
Pubmed

A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

1.09e-092469529992973
Pubmed

Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

1.69e-092669515857913
Pubmed

Molecular profiling of synovial joints: use of microarray analysis to identify factors that direct the development of the knee and elbow.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

3.03e-092969522972626
Pubmed

Genome-scale study of transcription factor expression in the branching mouse lung.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

2.33e-076769522711520
Pubmed

Gene content and function of the ancestral chromosome fusion site in human chromosome 2q13-2q14.1 and paralogous regions.

FOXD4L4 FOXD4L3 FOXD4

1.22e-061169312421752
Pubmed

Diverse fates of paralogs following segmental duplication of telomeric genes.

FOXD4L4 FOXD4L3 FOXD4

1.12e-052269315233989
Pubmed

Structural and functional analysis of the recombinant G domain of the laminin alpha4 chain and its proteolytic processing in tissues.

LAMA1 LAMA4

1.16e-05369210934193
Pubmed

Laminin isoform-specific promotion of adhesion and migration of human bone marrow progenitor cells.

LAMA1 LAMA4

1.16e-05369212393739
Pubmed

Novel Role of Prereplication Complex Component Cell Division Cycle 6 in Retinal Neovascularization.

NFATC1 CDC6

1.16e-05369235236105
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

FOXD4L4 TCF7L2 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

1.42e-0526369620932939
Pubmed

A threshold level of NFATc1 activity facilitates thymocyte differentiation and opposes notch-driven leukaemia development.

NFATC1 NOTCH3

2.32e-05469227312418
Pubmed

IL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages.

IL12RB1 IL16

2.32e-05469219100623
Pubmed

Laminin alpha 1, alpha 2, alpha 4 and beta 1 chain mRNA expression in mouse embryonic, neonatal, and adult hearts.

LAMA1 LAMA4

2.32e-0546929201115
Pubmed

Interactions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families.

ADAMTS10 ADAMTSL4

3.86e-05569229758265
Pubmed

Differential expression of five laminin alpha (1-5) chains in developing and adult mouse kidney.

LAMA1 LAMA4

3.86e-0556929415429
Pubmed

TRIB2 inhibits Wnt/β-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, β-TrCP, COP1 and Smurf1, in liver cancer cells.

TCF7L2 TRIB2

3.86e-05569225311538
Pubmed

Differential expression of laminin alpha chains during murine tooth development.

LAMA1 LAMA4

3.86e-0556929389447
Pubmed

HIV-protein-mediated alterations in T cell interactions with the extracellular matrix proteins and endothelium.

LAMA1 LAMA4

5.79e-0566929597096
Pubmed

A census of human transcription factors: function, expression and evolution.

FOXD4L4 TCF7L2 NFATC1 FOXD4L3 BHLHA9 ZNF398 RERE TOE1 FOXD4

7.55e-0590869919274049
Pubmed

Laminin isoforms in fetal and adult human adrenal cortex.

LAMA1 LAMA4

8.09e-05769214557481
Pubmed

Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.

LAMA1 LAMA4

1.08e-0486929852162
Pubmed

Expression of laminin alpha1, alpha2, alpha4, and alpha5 chains, fibronectin, and tenascin-C in skeletal muscle of dystrophic 129ReJ dy/dy mice.

LAMA1 LAMA4

1.38e-0496929882526
Pubmed

Characterization of a 190-kilobase pair domain of human type I hair keratin genes.

KRT38 KRT37

1.38e-0496929756910
Pubmed

Human hair keratins.

KRT38 KRT37

1.38e-0496927686952
Pubmed

Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.

LAMA1 LAMA4

1.73e-04106929034910
Pubmed

ADAMTS: a novel family of extracellular matrix proteases.

ADAMTS10 ADAMTS4

1.73e-041069211167130
Pubmed

The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.

KRT38 KRT37

1.73e-041069210391933
Pubmed

Integrin-laminin interactions controlling neurite outgrowth from adult DRG neurons in vitro.

LAMA1 LAMA4

1.73e-041069218590826
Pubmed

Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.

LAMA1 LAMA4

1.73e-041069211784026
Pubmed

Primary cellular meningeal defects cause neocortical dysplasia and dyslamination.

LAMA1 LAMA4

1.73e-041069220976766
Pubmed

Regulation of radial glial survival by signals from the meninges.

LAMA1 LAMA4

2.11e-041169219535581
Pubmed

Expression of Tcf/Lef and sFrp and localization of beta-catenin in the developing mouse lung.

TCF7L2 SFRP4

2.11e-041169211731265
Pubmed

Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung.

LAMA1 LAMA4

2.11e-041169212051813
Pubmed

Regional differences in the expression of laminin isoforms during mouse neural tube development.

LAMA1 LAMA4

2.11e-041169221524702
Pubmed

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.

TCF7L2 LAMA1

2.11e-041169222693455
Pubmed

Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.

LAMA1 LAMA4

2.11e-041169223472759
Pubmed

Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.

TCF7L2 SACS

2.11e-041169223300278
Pubmed

New genetic associations detected in a host response study to hepatitis B vaccine.

IL12RB1 IL16 FCGBP LMAN1 NFATC1 HRG ANKLE1 CR1

2.24e-0482469820237496
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

LMAN1 LAMA4 HRG ADAMTSL4

2.49e-0415369425037231
Pubmed

The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain.

KRT38 KRT37

2.53e-041269215617563
Pubmed

Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis.

LAMA1 LAMA4

2.53e-041269211381080
Pubmed

Wnt signalling induces maturation of Paneth cells in intestinal crypts.

EPHB3 TCF7L2

2.53e-041269215778706
Pubmed

Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.

LAMA1 LAMA4

2.53e-041269216750824
Pubmed

Expression of laminin receptors in schwann cell differentiation: evidence for distinct roles.

LAMA1 LAMA4

2.53e-041269212843252
Pubmed

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.

LAMA1 LAMA4

2.53e-04126929396756
Pubmed

RERE deficiency leads to decreased expression of GATA4 and the development of ventricular septal defects.

NFATC1 RERE

2.53e-041269230061196
Pubmed

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.

ADAMTS10 ADAMTS4

2.53e-041269225770910
Pubmed

The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.

LAMA1 LAMA4

2.98e-041369236350252
Pubmed

Fukutin-related protein alters the deposition of laminin in the eye and brain.

LAMA1 LAMA4

2.98e-041369221900571
Pubmed

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.

LNX2 IGHA1 TROAP LAMA4 CDC6

3.41e-0430269530561431
Pubmed

Defining brain wiring patterns and mechanisms through gene trapping in mice.

LAMA1 NOTCH3

3.48e-041469211242070
Pubmed

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.

LAMA1 LAMA4

3.48e-04146929151674
Pubmed

Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

3.62e-0430669518973680
Pubmed

Basement membrane composition in the early mouse embryo day 7.

LAMA1 LAMA4

4.01e-041569215895400
Pubmed

Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.

LAMA1 LAMA4

4.01e-041569210625553
Pubmed

Laminin alpha5 chain is required for intestinal smooth muscle development.

LAMA1 LAMA4

4.01e-041569212921739
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

LMAN1 LAMA1 LAMA4 HRG

4.15e-0417569428071719
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS10 ADAMTS4 ADAMTSL4

4.56e-047569320637190
Pubmed

Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.

LAMA1 LAMA4

4.57e-041669217601529
Pubmed

ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.

ADAMTS4 LAMA1

4.57e-041669230579834
Pubmed

Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.

LAMA1 LAMA4

4.57e-041669217948866
Pubmed

Laminin α1 is essential for mouse cerebellar development.

LAMA1 LAMA4

5.18e-041769221983115
Pubmed

Beta1-integrins are critical for cerebellar granule cell precursor proliferation.

LAMA1 LAMA4

5.18e-041769215056720
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

LAMA1 LAMA4 ADAMTSL4

5.31e-047969318757743
Pubmed

Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.

LAMA1 LAMA4

5.81e-041869211311202
Pubmed

Functional genomics analysis identifies loss of HNF1B function as a cause of Mayer-Rokitansky-Küster-Hauser syndrome.

LAMA1 LAMA4

5.81e-041869236282544
Pubmed

Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.

LAMA1 LAMA4

7.20e-042069222911573
Pubmed

Ephrin-B2 governs morphogenesis of endolymphatic sac and duct epithelia in the mouse inner ear.

EPHB3 NOTCH3

7.95e-042169224583262
Pubmed

Hereditary Ataxia Overview

SACS LAMA1 SLC9A6

8.27e-049269320301317
Pubmed

Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.

LAMA1 LAMA4

8.73e-042269228334989
Pubmed

A proteomic analysis of human bile.

FCGBP IGHA1

8.73e-042269215084671
Pubmed

FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation.

LMAN1 MUC19

8.73e-042269237838739
Pubmed

Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.

LAMA1 LAMA4

8.73e-042269235245678
Pubmed

Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade.

NFATC1 NOTCH3

9.55e-042369231789590
Pubmed

Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis.

LAMA1 LAMA4

1.13e-032569219373938
Pubmed

A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells.

SACS ZNF619 USH2A

1.21e-0310569323284306
Pubmed

Developmental origins for semilunar valve stenosis identified in mice harboring congenital heart disease-associated GATA4 mutation.

TCF7L2 NFATC1

1.22e-032669231138536
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

LAMA1 LAMA4

1.22e-032669224742657
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

LAMA1 NOTCH3

1.22e-032669234189436
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SPEG DISP2 RERE SLC23A2 SLC9A6

1.30e-0340769512693553
Pubmed

Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis.

TCF7L2 NFATC1

1.32e-032769223824573
Pubmed

GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.

STAB2 LAMA4

1.42e-032869228218627
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CELSR1 NFATC1 SPEG SNX8 ZNF398 DISP2 ANKLE1 ADGRA2

1.52e-03110569835748872
Pubmed

Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.

ADAMTS4 NOTCH3

1.63e-033069219054571
Pubmed

pRb-mediated control of epithelial cell proliferation and Indian hedgehog expression in mouse intestinal development.

TCF7L2 NOTCH3

1.63e-033069217257418
Cytoband9q21.11

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5

1.24e-07306949q21.11
Cytoband17q12-q21

KRTAP3-1 KRTAP4-16 KRT38 KRT37

1.63e-073269417q12-q21
CytobandEnsembl 112 genes in cytogenetic band chr17q21

KRTAP3-1 CDC6 KRTAP4-16 KRT38 KRT37 KCNH4

8.03e-05473696chr17q21
Cytoband3q21

EPHB3 LINC01565

6.01e-04246923q21
GeneFamilyLaminin subunits

LAMA1 LAMA4

3.94e-0412452626
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS10 ADAMTS4

1.01e-031945250
GeneFamilyKeratins, type I

KRT38 KRT37

2.20e-0328452608
GeneFamilyFibronectin type III domain containing

EPHB3 IL12RB1 USH2A

7.35e-03160453555
CoexpressionMEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3

FOXD4L4 CELSR1 FOXD4L3 LAMA1 CACNA1I FOXD4L6 FOXD4L5 FOXD4

3.55e-06357678MM828
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K27ME3

FOXD4L4 CELSR1 FOXD4L3 FOXD4L6 NOTCH3 FOXD4L5 FOXD4

7.76e-06282677MM822
CoexpressionMORI_MATURE_B_LYMPHOCYTE_UP

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

7.78e-06106675MM595
CoexpressionNABA_MATRISOME

ADAMTS10 PODNL1 IL16 SFRP4 LMAN1 ADAMTS4 LAMA1 MUC19 LAMA4 HRG USH2A ADAMTSL4

9.97e-0610266712M5889
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3

FOXD4L4 FOXD4L3 LAMA1 FOXD4L6 FOXD4L5 FOXD4

1.97e-05217676MM861
CoexpressionNABA_MATRISOME

ADAMTS10 PODNL1 IL16 SFRP4 LMAN1 ADAMTS4 LAMA1 MUC19 LAMA4 HRG ADAMTSL4

4.60e-0510086711MM17056
CoexpressionKRAS.600_UP.V1_DN

EPHB3 PODNL1 FCGBP CIITA CACNA1I KRT38

7.98e-05279676M2880
ToppCellfacs-Skin-Anagen-3m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS10 PODNL1 IL12RB1 IL16 NEURL3 SACS CLNK

1.14e-081776977853430fb0d1a18d835e8956777e0616c5d7d412
ToppCellfacs-Skin-Anagen-3m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS10 PODNL1 IL12RB1 IL16 NEURL3 SACS CLNK

1.14e-08177697395f005f019aabb18738d3a10a04c37f216deda3
ToppCellfacs-Skin-Anagen-3m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS10 PODNL1 IL12RB1 IL16 NEURL3 SACS CLNK

1.14e-081776979a5bf67a801826d094f679dd2189b62296c9694f
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TROAP SIRPB2 CDC6 CR1 ADAMTSL4 TOE1 WDR62

2.38e-08197697d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-T_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODNL1 IL12RB1 KRBA1 CELSR1 ADAMTS4 CLNK

3.32e-07177696baf78a8dad55f124f56585f88b10b58c0269680f
ToppCellLPS-IL1RA-Endothelial-Mes-Like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SACS SPEG OTUD7A ZNF619 NOTCH3

3.09e-0614569590ca38c02325c5c637c32efdef634b54cc3cd105
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PODNL1 IL12RB1 STAB2 CDC6 CLNK

6.15e-0616769553e32d6687a07f486141df9f4ab998af4c03a507
ToppCellfacs-Heart-LV-3m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODNL1 IL16 STAB2 INAVA CLNK

6.71e-061706952491f3849e34b0ccd06015fa59d15e3d7963c76d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TROAP DISP2 CDC6 NOTCH3 WDR62

6.90e-06171695b0373ed8283ee1792b6a490bff93906546978593
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TROAP DISP2 CDC6 NOTCH3 WDR62

6.90e-06171695b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

AFF2 SPEG LAMA4 ADGRA2 NOTCH3

7.10e-06172695858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTS10 AFF2 ADAMTS4 SPEG NOTCH3

7.31e-061736955416b092321c7d9b63f0418c60f2402a138355bf
ToppCellwk_15-18-Hematologic-Myeloid-aDC_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4

8.16e-06177695ccf5dc54780d6039a4d062dee88440c011ddc0a3
ToppCellwk_20-22-Hematologic-Myeloid-aDC_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FOXD4L4 NEURL3 FOXD4L3 FOXD4L6 FOXD4

8.39e-06178695fd2bdb4796e86c8cff2d25f0c730ffea21db8787
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-NK_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODNL1 IL12RB1 CELSR1 STAB2 CLNK

8.62e-061796956f657c7a227f860934d0dfec9b97d35fd2cedfd2
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FOXD4L4 NEURL3 FOXD4L3 FOXD4L5 FOXD4

8.85e-0618069532d871738a24071b70084a7e80148a516110c78b
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FOXD4L4 NEURL3 FOXD4L3 FOXD4L5 FOXD4

8.85e-06180695067ca8a15228c7f3b3bc7aecbc9b1611ca05e176
ToppCellwk_08-11-Hematologic-Myeloid-DC1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

IL12RB1 IL16 CIITA KLHDC7B CLNK

1.06e-051876952907cc0b8789c5e1468917caa21fa0feb025305e
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS10 FCGBP NEURL3 INAVA NOTCH3

1.24e-051936958ede7038a222c7e7ecaf7e86520823cf606cbee7
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS10 FCGBP NEURL3 INAVA NOTCH3

1.24e-051936950e7d7adfaa7191e34038fcda6677561ae13934eb
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B_plasma-Plasmablasts|lymph-node_spleen / Manually curated celltypes from each tissue

LMAN1 IGHA1 TROAP CDC6 WDR62

1.30e-051956951390728b9a514db534e8bc6dcf72cf51a1065780
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SACS SPEG LAMA4 ADGRA2 NOTCH3

1.37e-05197695bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS10 ADAMTS4 SPEG ADGRA2 NOTCH3

1.40e-051986957dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CIITA IGHA1 SNX8 CLNK CR1

1.40e-05198695824461cf44098440ba8bc0df96735423ac65bda1
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_cell-B_mature|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CIITA IGHA1 SNX8 CLNK CR1

1.40e-05198695863765ccc0205dc28864dae85af339c283194c96
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 SPEG LAMA4 ADGRA2 NOTCH3

1.44e-0519969520f760d92c351a1dac4cc0a424c443ea03a179fe
ToppCellmetastatic_Brain-Fibroblasts|metastatic_Brain / Location, Cell class and cell subclass

SFRP4 ADAMTS4 LAMA4 ADGRA2 NOTCH3

1.44e-0519969563eb2106bb6e2e33d020628583536c8d96662c84
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 SPEG LAMA4 ADGRA2 NOTCH3

1.44e-051996957c272a1aa7f3e931ad5d20809719d85b3bce4cb0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Stem_cells|GW10 / Sample Type, Dataset, Time_group, and Cell type.

CELSR1 TCF7L2 TROAP CDC6 WDR62

1.47e-052006954c22a1f35ff496fa6af2ab171f2936785272bc06
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-OPC_related-OPC|GW26 / Sample Type, Dataset, Time_group, and Cell type.

TCF7L2 TRIB2 TROAP LAMA4 INAVA

1.47e-0520069502594c1edbc9f2cf831639cd83363abd2551cb94
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 SACS SPEG LAMA4 NOTCH3

1.47e-05200695a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-OPC_related|GW26 / Sample Type, Dataset, Time_group, and Cell type.

TCF7L2 TRIB2 TROAP LAMA4 INAVA

1.47e-0520069546521d83b917b0357601db8783c8da6b73730d60
ToppCellParenchyma_COVID-19-Stromal-TX-Smooth_muscle-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

AFF2 ADAMTS4 LAMA4 ADGRA2 NOTCH3

1.47e-0520069578e9a40153d7ba5d9ea6393a37d26fc5c0220867
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

AFF2 ADAMTS4 LAMA4 ADGRA2 NOTCH3

1.47e-05200695c46e06b4f22d3456e67bc62a9ac198e8041965ad
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AFF2 ADAMTS4 LAMA4 ADGRA2 NOTCH3

1.47e-0520069543b76e382b38b9856c07557a75e5b1ce0cee1d9e
ToppCellParenchymal-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AFF2 ADAMTS4 LAMA4 ADGRA2 NOTCH3

1.47e-05200695f9bc22ff17bb1c751e6b05bca3f403836f33459a
ToppCellParenchymal-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AFF2 ADAMTS4 LAMA4 ADGRA2 NOTCH3

1.47e-052006950a7640db28c708003d5da2d19eb651f6fedfd710
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Stem_cells-Neuroepithelial_cell|GW10 / Sample Type, Dataset, Time_group, and Cell type.

CELSR1 TCF7L2 TROAP CDC6 WDR62

1.47e-052006950632b8d3a1be437f146bc86aae9646303e37a0bd
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P1|Hippocampus / BrainAtlas - Mouse McCarroll V32

PODNL1 IL12RB1 ADAMTS4 INAVA

2.68e-05111694bb59f1909645fd512f0ea806e5593d4a1c6e25d9
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Ccnb1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TROAP ANKLE1 INAVA WDR62

4.83e-05129694ff74d159034a09f7b174da18bfb9a26936252b4c
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SFRP4 SPEG ZNF398 TOE1

5.93e-05136694a2063abe2d7c3277bfbe1514c8c66363cf04b248
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PODNL1 IL12RB1 STAB2 CLNK

6.82e-05141694d3ce2218bfa9750795d920e1ef162ea44efb2e66
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-3|TCGA-Stomach / Sample_Type by Project: Shred V9

ADAMTS10 PODNL1 STAB2 ADGRA2

8.23e-05148694c95a732163050cfb5d604c2a4c9eb1afa9f19a95
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PODNL1 IL12RB1 STAB2 CLNK

8.90e-051516941525422afadff68a1525ced6d5db45fdea450678
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PODNL1 IL12RB1 STAB2 CLNK

9.60e-05154694d0a1ff02a7e91f6923aa85b65094f78e357e377d
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PODNL1 IL12RB1 CACNA1I CLNK

9.84e-05155694efe69145910c5e049d0ed30699c26ef963e0a285
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TROAP ANKLE1 CDC6 WDR62

1.14e-041616940dd1401b4c990d49fccb702a9f9867590a58e203
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TROAP ANKLE1 CDC6 WDR62

1.14e-04161694b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TROAP ANKLE1 CDC6 WDR62

1.14e-04161694efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TROAP ANKLE1 CDC6 WDR62

1.14e-0416169428d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTS10 AFF2 ADAMTS4 SPEG

1.19e-041636948f24cef152f5965727bbeee116bd26c75cbba82a
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PODNL1 IL12RB1 STAB2 CLNK

1.19e-04163694476e94e1d132eaaecb9e376bd32748a75ad22081
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL12RB1 CIITA SACS CLNK

1.25e-041656940c80abf13409767825ef8a507b498afafa7e89c5
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PODNL1 IL12RB1 TROAP CLNK

1.25e-0416569426c750f10f6401752e2e63d91dc844c81b29d735
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL12RB1 CIITA SACS CLNK

1.25e-04165694cced77f2d74b07010307d7f4788b8cf3fdaeb91a
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTS10 AFF2 SPEG NOTCH3

1.25e-041656948a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS10 ADAMTS4 ADGRA2 NOTCH3

1.31e-04167694e228b8373ffd4436e6b944e26d0fadf3ac289b21
ToppCellAdult-Epithelial-lung_goblet_cell-D122|Adult / Lineage, Cell type, age group and donor

ADAMTS10 CELSR1 FCGBP INAVA

1.31e-041676946efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS10 ADAMTS4 ADGRA2 NOTCH3

1.31e-041676947cb1b11e8e24a10115e46ffbb74889e672a7a026
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS10 ADAMTS4 ADGRA2 NOTCH3

1.31e-04167694bb53a478b5d821d6d82c15bc4ed075b67682457c
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PODNL1 IL12RB1 STAB2 CLNK

1.31e-0416769484551ee71f9d8d03d514711fc7ca4422c810140b
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP|Hippocampus / BrainAtlas - Mouse McCarroll V32

LAMA1 HRG ADGRA2 ADAMTSL4

1.34e-0416869426aa96b2b547d11941cb803995ea3d302ee0518c
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD4L4 FOXD4L3 FOXD4L6 FOXD4

1.34e-041686946dd58fd981750da49afd53796f244e1803cce97f
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PODNL1 IL12RB1 IL16 CELSR1

1.34e-041686946c758eb120faf06ff72d157b495e399191c79ec9
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF2 ADAMTS4 ADAMTSL4 NOTCH3

1.37e-041696942d23b4cee060f8adddc430c1c10d4e25205b4af6
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF2 ADAMTS4 ADAMTSL4 NOTCH3

1.37e-04169694ecaf08e8e0b54d1c97a02bc1f65409fd43d68227
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF2 ADAMTS4 ADAMTSL4 NOTCH3

1.37e-04169694ad6af6609acf158cb79e45ee7ca9af332be3c40c
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IL12RB1 TCF7L2 ADAMTS4 INAVA

1.37e-0416969450cc0f5a022b95986949db63208a627cef9f4a69
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFF2 LAMA4 CDC6 NOTCH3

1.47e-0417269403a0aff6b7971093a4347b5ed12546d78374c56f
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

IL12RB1 STAB2 LAMA4 ADGRA2

1.47e-04172694c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCell5'-Adult-Distal_Rectal-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KRBA1 CIITA IGHA1 SNX8

1.50e-04173694b335ca2a247156eba821943b2b9fc9922230b409
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODNL1 STAB2 NEURL3 KCTD18

1.50e-041736946e92983d9f8a2a37f23e60a0d5bb1738217897bc
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SACS TROAP CDC6 WDR62

1.50e-0417369420889aa85e36ad3bafdb91b91e43964493c949f9
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Alox5+_Lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODNL1 STAB2 NEURL3 KCTD18

1.50e-041736944c788c1dad1da495b3b5c10f95e779848dfe85dc
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SACS TROAP CDC6 WDR62

1.50e-0417369446e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCellmetastatic_Lymph_Node-Endothelial_cells-Lymphatic_ECs|metastatic_Lymph_Node / Location, Cell class and cell subclass

STAB2 ADAMTS4 LAMA4 ADGRA2

1.54e-04174694d551bc29afef071adf4c9bb80345352ec33441d8
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PODNL1 IL12RB1 IL16 CELSR1

1.54e-041746947c8cc5c2872fc7bcca7ebddaf5a6f20e617a2674
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

TROAP INAVA CDC6 WDR62

1.57e-04175694fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

TROAP INAVA CDC6 WDR62

1.57e-0417569436c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIITA MUC19 CACNA1I USH2A

1.60e-04176694c6484334187f64cd00cd35e77d8ae436556b4260
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-cDC1|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL16 CIITA SIRPB2 CLNK

1.60e-0417669487f90834c7278516beff7814b78f7c75732d9bf0
ToppCellfacs-MAT-Fat-3m-Lymphocytic-T_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODNL1 STAB2 NEURL3 SACS

1.60e-0417669471b3309ddadd035a1224fca4fc5946dc4c0283fe
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

ADAMTS4 LAMA4 ADGRA2 NOTCH3

1.60e-041766942015539c58aa0bb118e111ffedd63dd9fe863bb1
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-2|TCGA-Colorectal / Sample_Type by Project: Shred V9

TRIB2 NFATC1 CIITA KLHDC7B

1.60e-041766941870860a9ebe7a655c4ea8898427e1097ee23113
ToppCell10x3'2.3-week_12-13-Lymphocytic_T-T_NK-NK_T_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

IL12RB1 IL16 TRIB2 INAVA

1.64e-04177694e1ba7e17af2c54d3c78cdf85882168c5b896e453
ToppCellmetastatic_Lymph_Node-Endothelial_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

STAB2 ADAMTS4 LAMA4 ADGRA2

1.64e-0417769471bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCell10x5'-Liver-Lymphocytic_B_plasma-Plasmablasts|Liver / Manually curated celltypes from each tissue

LMAN1 IGHA1 TROAP CDC6

1.64e-041776941d88ae316d65ca5fdc736c9da93885b6b40c32bb
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB3 FCGBP ANKLE1 ZNF619

1.64e-04177694e1e45956887371b1c18f1eb479dd930031497520
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AFF2 ADAMTS4 ADGRA2 NOTCH3

1.64e-04177694452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCellNS-moderate-d_0-4-Lymphoid-NKT-proliferating|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADAMTS4 TROAP CDC6 WDR62

1.64e-04177694174c54acfe19e2bb31418d69e228032ba724cbb6
ToppCell3'-Adult-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS10 IL16 KRBA1 TRIB2

1.64e-04177694bb496fbec7cacc52847abe2b2714249c47879763
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7L2 TROAP SPEG KCNH4

1.68e-04178694de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

ADAMTS10 SFRP4 ADAMTS4 ADGRA2

1.68e-04178694142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCelldroplet-Tongue-nan-24m-Myeloid-basal_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODNL1 IL12RB1 IL16 NEURL3

1.68e-041786949423e209de94d26e96117581c95dc069850225d3
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS4 TROAP ADGRA2 WDR62

1.75e-0418069440d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCellnormal_Lung-Myeloid_cells-CD207+CD1a+_LCs|normal_Lung / Location, Cell class and cell subclass

FCGBP TROAP CLNK WDR62

1.79e-04181694b55dbcfae8c92d322071906831489830a22239b9
ToppCellEndothelial-B-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

STAB2 NFATC1 LAMA4 ADGRA2

1.79e-041816944fe0215d08f03d4e24749d70fce01b7aa22906fd
ToppCellfacs-GAT-Fat-3m-Lymphocytic-T_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODNL1 IL12RB1 NEURL3 CLNK

1.82e-04182694751bd3e3b49de961523e98197688a05c998c121a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADAMTS4 LAMA4 ADGRA2 NOTCH3

1.82e-04182694fc4a5bf784705efe7965ce43ac23c2a8e602e90a
ToppCellIPF-Myeloid-DC_Langerhans|World / Disease state, Lineage and Cell class

FCGBP CIITA SNX8 CLNK

1.82e-041826940e8cfbd8ea196f27a227dbb4d2eb93bc48d27922
DrugPhenacetin [62-44-2]; Up 200; 22.4uM; MCF7; HT_HG-U133A

TCF7L2 TRIB2 STAB2 LMAN1 INPP4A LAMA4 CACNA1I

1.54e-061896872832_UP
Drugindomethacin, USP; Up 200; 20uM; MCF7; HG-U133A

IL12RB1 TCF7L2 HRG CACNA1I RERE ADGRA2 NOTCH3

1.77e-06193687262_UP
DrugSpectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A

PODNL1 IL12RB1 STAB2 LAMA4 CACNA1I ADGRA2 SLC23A2

1.89e-061956873327_UP
DrugDibucaine [85-79-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A

PODNL1 IL16 NFATC1 INPP4A CACNA1I ADGRA2 NOTCH3

1.96e-061966874149_UP
Drugchlorpropamide; Up 200; 100uM; MCF7; HG-U133A

AFF2 CIITA LAMA4 CACNA1I CR1 SLC23A2 ADAMTSL4

2.02e-06197687141_UP
DrugBretylium tosylate [61-75-6]; Down 200; 9.6uM; MCF7; HT_HG-U133A

EPHB3 TCF7L2 STAB2 INPP4A SPEG RERE

2.72e-051976863394_DN
DrugFlavoxate hydrochloride [3717-88-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A

EPHB3 PODNL1 TCF7L2 TRIB2 INPP4A WDR62

2.72e-051976867405_UP
DrugHydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; HL60; HG-U133A

PODNL1 TRIB2 LMAN1 AFF2 CIITA CR1

2.88e-051996861436_UP
DrugNoscapine [128-62-1]; Up 200; 9.6uM; MCF7; HT_HG-U133A

IL12RB1 IL16 LMAN1 SPEG CACNA1I ADGRA2

2.97e-052006867204_UP
Diseaseadverse effect, response to xenobiotic stimulus

STAB2 FAM86C1P LAMA1

2.64e-0459623EFO_0009658, GO_0009410
DiseaseImpaired cognition

CR1 NOTCH3

3.89e-0414622C0338656
DiseaseTourette syndrome, schizophrenia

CACNA1I RERE

6.50e-0418622EFO_0004895, MONDO_0005090
DiseaseColorectal Carcinoma

TCF7L2 SFRP4 NFATC1 SACS LAMA1 SNX8 KCNH4

6.62e-04702627C0009402
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

TCF7L2 AFF2 ADAMTS4

1.42e-03105623DOID:9352 (implicated_via_orthology)
Diseaseeosinophil measurement

LINC01565 ZNF398 METTL17

1.54e-03108623EFO_0803540
Diseaseeyelid sagging measurement

EPHB3 SFRP4

2.07e-0332622EFO_0009360
Diseaseblood pressure, chronic obstructive pulmonary disease

LINC00322 RERE

2.07e-0332622EFO_0000341, EFO_0004325

Protein segments in the cluster

PeptideGeneStartEntry
PPRTPTPGASDCHCL

ANKLE1

306

Q8NAG6
SNCSHLPRPPALQPC

ADAMTSL4

951

Q6UY14
RACCPPASPAAPHAP

ADGRA2

1081

Q96PE1
LHSTCGPAPAEPCSL

CIITA

511

P33076
PSAPRCASCPPHAPL

BHLHA9

171

Q7RTU4
CASCPPHAPLARPSA

BHLHA9

176

Q7RTU4
TICLLPPCISPAPPH

AFF2

876

P51816
ATLCSLPSCPPFIPL

EFL1

596

Q7Z2Z2
RTLLCHCGPFLTPPS

LINC01565

101

O15544
ALAAPTTLPACRCPP

CELSR1

146

Q9NYQ6
LQLHDGPCCSRPPPA

DISP2

1196

A7MBM2
SACPQPRPPVLEACH

ADAMTS10

926

Q9H324
PCPSTMPSTACHPHL

INPP4A

596

Q96PE3
PPVLPASSLQPPCHC

KRBA1

781

A5PL33
CPLPVLPRIPSSDCH

LNP1

51

A1A4G5
PPPLLPMSCSSCQHA

HRG

316

P04196
ATPAPFPCCSPHLVL

FOXD4L4

291

Q8WXT5
ATPAPFPCCSPHLVL

FOXD4L3

291

Q6VB84
SLCLPPTSHTACPLP

KRT37

66

O76014
PLPSATQRCASCSPP

FAM86C1P

121

Q9NVL1
PLGRPSLCLPPTCHT

KRT38

61

O76015
SLCLPPTCHTACPLP

KRT38

66

O76015
PLLQPLDTPCGHTFC

LNX2

56

Q8N448
CLPSTCPHEISLLQP

KRTAP3-1

31

Q9BYR8
CLASLPPAPVCHGPL

MUC19

8151

Q7Z5P9
PPSLCSHLSPPLCRS

IL16

306

Q14005
LPLPTAHSTLPAPCH

NFATC1

56

O95644
LCLPPSHPCAHEPCS

NOTCH3

691

Q9UM47
CLSPCASRPPPSLQD

KCNH4

936

Q9UQ05
CPELPPFPSCLSTVH

LMAN1

466

P49257
CLPCPPNSRTTSPAA

EPHB3

301

P54753
STCPHPLCCASPPLP

KRTAP4-16

151

G5E9R7
PLEVPPNRCHCSPLV

OTUD7A

346

Q8TE49
LATPAPFPCCSPHLV

FOXD4

286

Q12950
TVPRAPPSPCLPCHV

PODNL1

491

Q6PEZ8
RTPLCATAPCLPSPT

KCTD18

381

Q6PI47
DSRHCPQLPPPCAAL

ADAMTS4

456

O75173
PSCSRVCQPPPDVLH

CR1

291

P17927
PSCSRVCQPPPDVLH

CR1

741

P17927
PSCSRVCQPPPEILH

CR1

1191

P17927
PAPRCELSVPAACPH

CR1

1836

P17927
CLAGCFLPVPSSPHT

LINC00322

81

Q6ZN03
ASCPSPAPLTTPAVC

FCGBP

3166

Q9Y6R7
PIPATLASDPASCPC

CACNA1I

541

Q9P0X4
PTPSPSCCHPRLSLH

IGHA1

116

P01876
DDNLCNTPHLPPCSP

CDC6

61

Q99741
HLCPPLPTPCASSAI

IL12RB1

576

P42701
AASLPLPAPAPLHCT

KLHDC7B

521

Q96G42
PCIPCSLEGHPLVLP

SACS

2096

Q9NZJ4
SCFPATKPPLPHAAC

INAVA

436

Q3KP66
APCPHELPCPQLTNL

METTL17

331

Q9H7H0
PCPCPLPHLANFAES

LAMA4

131

Q16363
FHVACPPDSALPCTP

USH2A

4866

O75445
THSGPPLTTTLPACC

SLC9A6

551

Q92581
SCLFAGPHSTLTPPC

SNX8

441

Q9Y5X2
ATPAPFPCCSPHLVL

FOXD4L5

291

Q5VV16
ATPAPFPCCSPHLVL

FOXD4L6

291

Q3SYB3
LCACPHSPPASFSPT

LAMA1

1451

P25391
PGLPSCSTVHCFIPP

PRR32

236

B1ATL7
RSPTPALCDPPACSL

RERE

141

Q9P2R6
CQPPASCSPHENILP

CLNK

271

Q7Z7G1
SAPTCLAHLPPCFLL

SIRPB2

6

Q5JXA9
WSTCPPHPLPSCLTA

PP632

6

Q6XCG6
PHPLPSCLTACCSPA

PP632

11

Q6XCG6
ATLLCLPAACPAPHI

SPEG

2601

Q15772
CARLSCAPPPPIHAI

SLC23A2

401

Q9UGH3
PSPPETPNLSHCVSC

TRIB2

46

Q92519
PLITNSSCQCPHILP

SFRP4

236

Q6FHJ7
TPPTCPHCARTFTHP

ZNF398

396

Q8TD17
HSECFLNPCLSLPPI

TCF7L2

441

Q9NQB0
SQHPLCASPPICSLQ

TROAP

676

Q12815
CASPPICSLQSLRPP

TROAP

681

Q12815
VLPAVCTPPCSAHAT

STAB2

2046

Q8WWQ8
ACVSVPSLPPFLCPD

NEURL3

86

Q96EH8
PPPCLTSLASCVPAS

WDR62

1166

O43379
PCAILSPLPPQHTCS

ZNF619

481

Q8N2I2
CLPPATHRPHPTSIC

TOE1

286

Q96GM8