Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbeta-2 adrenergic receptor binding

PDE4D NEDD4 PRKAR2A

2.65e-05101233GO:0031698
GeneOntologyBiologicalProcessnegative regulation of extrinsic apoptotic signaling pathway

DAB2 BCL2L1 SCG2 FGA FGB ARHGEF2 FCMR

5.45e-061131247GO:2001237
GeneOntologyCellularComponentperinuclear region of cytoplasm

PDE4D DAB2 HIP1R NDRG2 KIF20B RYR3 NEDD4 TG FAT1 SYNJ1 AIFM1 OSBPL3 PRKAR2A STH DOCK6 RAB29 MTMR9

5.10e-0593412717GO:0048471
GeneOntologyCellularComponentcentrosome

CCDC14 PDE4D USP9X CEP290 CHD4 BCL2L1 LCK KMT2E FIGN KIF20B AKAP9 PRKAR2A AJUBA PCM1

2.48e-0477012714GO:0005813
MousePhenoabnormal brain size

ANKFY1 TCF20 CASP9 ARID1A CSMD3 KIF20B TG AIFM1 RNF10 ARHGEF2 ADIPOR2 PCM1

1.62e-0537510112MP:0000771
DomainBAF250/Osa

ARID1A ARID1B

4.44e-0521252IPR021906
DomainBAF250_C

ARID1A ARID1B

4.44e-0521252IPR033388
DomainBAF250_C

ARID1A ARID1B

4.44e-0521252PF12031
DomainDHR-1_domain

DOCK4 DOCK11 DOCK6

4.64e-05111253IPR027007
DomainDHR_2

DOCK4 DOCK11 DOCK6

4.64e-05111253PS51651
DomainDHR_1

DOCK4 DOCK11 DOCK6

4.64e-05111253PS51650
DomainDHR-2

DOCK4 DOCK11 DOCK6

4.64e-05111253PF06920
DomainDOCK

DOCK4 DOCK11 DOCK6

4.64e-05111253IPR026791
DomainDOCK_C

DOCK4 DOCK11 DOCK6

4.64e-05111253IPR010703
DomainDOCK-C2

DOCK4 DOCK11 DOCK6

4.64e-05111253PF14429
DomainDHR-2

DOCK4 DOCK11 DOCK6

4.64e-05111253IPR027357
DomainLAM_G_DOMAIN

FAT4 FAT3 FAT1 CELSR2

1.18e-04381254PS50025
DomainFib_alpha

FGA FGB

1.33e-0431252SM01212
DomainFib_alpha

FGA FGB

1.33e-0431252PF08702
DomainFibrinogen_a/b/g_coil_dom

FGA FGB

1.33e-0431252IPR012290
DomainLaminin_G_2

FAT4 FAT3 FAT1 CELSR2

1.45e-04401254PF02210
DomainLamG

FAT4 FAT3 FAT1 CELSR2

2.11e-04441254SM00282
DomainFibrinogen_CS

TNN FGA FGB

2.62e-04191253IPR020837
Domain-

FAT4 FAT3 LGALS8 FAT1 CELSR2

4.44e-049512552.60.120.200
DomainFibrinogen_a/b/g_C_2

TNN FGA FGB

5.34e-04241253IPR014715
Domain-

TNN FGA FGB

5.34e-042412534.10.530.10
DomainASX_HYDROXYL

FAT4 FAT3 FAT1 CELSR2 C1S

5.62e-041001255PS00010
DomainLaminin_G

FAT4 FAT3 FAT1 CELSR2

6.14e-04581254IPR001791
DomainDUF3398

DOCK11 DOCK6

6.55e-0461252PF11878
DomainDOCK_C/D_N

DOCK11 DOCK6

6.55e-0461252IPR021816
DomainTNFR

TNFRSF11A CELSR2 TNFRSF19

6.80e-04261253SM00208
DomainEGF-type_Asp/Asn_hydroxyl_site

FAT4 FAT3 FAT1 CELSR2 C1S

7.32e-041061255IPR000152
DomainFibrinogen_C

TNN FGA FGB

7.61e-04271253PF00147
DomainCadherin_CS

FAT4 PCDHGC5 FAT3 FAT1 CELSR2

8.31e-041091255IPR020894
DomainFBG

TNN FGA FGB

9.42e-04291253SM00186
DomainCADHERIN_1

FAT4 PCDHGC5 FAT3 FAT1 CELSR2

9.77e-041131255PS00232
DomainCadherin

FAT4 PCDHGC5 FAT3 FAT1 CELSR2

9.77e-041131255PF00028
DomainCADHERIN_2

FAT4 PCDHGC5 FAT3 FAT1 CELSR2

1.02e-031141255PS50268
Domain-

FAT4 PCDHGC5 FAT3 FAT1 CELSR2

1.02e-0311412552.60.40.60
Domain-

TNN FGA FGB

1.04e-033012533.90.215.10
DomainFibrinogen_a/b/g_C_1

TNN FGA FGB

1.04e-03301253IPR014716
DomainCA

FAT4 PCDHGC5 FAT3 FAT1 CELSR2

1.06e-031151255SM00112
DomainCadherin-like

FAT4 PCDHGC5 FAT3 FAT1 CELSR2

1.10e-031161255IPR015919
DomainCadherin

FAT4 PCDHGC5 FAT3 FAT1 CELSR2

1.19e-031181255IPR002126
DomainFIBRINOGEN_C_1

TNN FGA FGB

1.26e-03321253PS00514
DomainFibrinogen_a/b/g_C_dom

TNN FGA FGB

1.26e-03321253IPR002181
DomainFIBRINOGEN_C_2

TNN FGA FGB

1.26e-03321253PS51406
DomainEGF_CA

FAT4 FAT3 FAT1 CELSR2 C1S

1.38e-031221255SM00179
DomainTNFR/NGFR_Cys_rich_reg

TNFRSF11A CELSR2 TNFRSF19

1.38e-03331253IPR001368
DomainEGF-like_Ca-bd_dom

FAT4 FAT3 FAT1 CELSR2 C1S

1.48e-031241255IPR001881
DomainDUF1220

NBPF4 NBPF6

1.55e-0391252SM01148
DomainEGF_1

FAT4 FAT3 ITGB7 FAT1 CELSR2 TNN C1S

1.66e-032551257PS00022
DomainEGF-like_CS

FAT4 FAT3 ITGB7 FAT1 CELSR2 TNN C1S

1.89e-032611257IPR013032
DomainIPPc

INPP5E SYNJ1

1.93e-03101252IPR000300
DomainIPPc

INPP5E SYNJ1

1.93e-03101252SM00128
DomainEGF_2

FAT4 FAT3 ITGB7 FAT1 CELSR2 TNN C1S

2.06e-032651257PS01186
DomainDUF1220

NBPF4 NBPF6

2.35e-03111252PF06758
DomainNBPF_dom

NBPF4 NBPF6

2.35e-03111252IPR010630
DomainNBPF

NBPF4 NBPF6

2.35e-03111252PS51316
DomainEGF_CA

FAT4 FAT3 FAT1 C1S

2.66e-03861254PF07645
DomainTTL

TTLL2 TTLL13

3.30e-03131252PS51221
DomainTTL/TTLL_fam

TTLL2 TTLL13

3.30e-03131252IPR004344
DomainTTL

TTLL2 TTLL13

3.30e-03131252PF03133
DomainConA-like_dom

FAT4 FAT3 RYR3 LGALS8 FAT1 CELSR2

3.58e-032191256IPR013320
DomainEGF_Ca-bd_CS

FAT4 FAT3 FAT1 C1S

4.10e-03971254IPR018097
DomainCUB

CSMD3 C1S CSMD1

4.31e-03491253PF00431
Domain-

ARID1A ARID1B

4.41e-031512521.10.150.60
DomainBRIGHT

ARID1A ARID1B

4.41e-03151252SM00501
DomainARID_dom

ARID1A ARID1B

4.41e-03151252IPR001606
DomainARID

ARID1A ARID1B

4.41e-03151252PS51011
DomainARID

ARID1A ARID1B

4.41e-03151252PF01388
DomainEGF_CA

FAT4 FAT3 FAT1 C1S

4.41e-03991254PS01187
DomainCUB

CSMD3 C1S CSMD1

4.56e-03501253SM00042
DomainEGF_3

FAT4 FAT3 FAT1 CELSR2 TNN C1S

5.04e-032351256PS50026
Domain-

CSMD3 C1S CSMD1

5.09e-035212532.60.120.290
DomainSushi

CSMD3 C1S CSMD1

5.09e-03521253PF00084
DomainCUB

CSMD3 C1S CSMD1

5.37e-03531253PS01180
DomainCCP

CSMD3 C1S CSMD1

5.66e-03541253SM00032
DomainSUSHI

CSMD3 C1S CSMD1

6.27e-03561253PS50923
DomainSushi_SCR_CCP_dom

CSMD3 C1S CSMD1

6.58e-03571253IPR000436
DomainCUB_dom

CSMD3 C1S CSMD1

6.58e-03571253IPR000859
DomainEGF-like_dom

FAT4 FAT3 FAT1 CELSR2 TNN C1S

6.64e-032491256IPR000742
PathwayREACTOME_RHO_GTPASE_CYCLE

DOCK4 ANKFY1 DOCK11 USP9X NCF1 ARHGEF18 LCK FAM13A NISCH KCTD3 ARHGEF2 DOCK6

3.47e-054509212M27078
PathwayREACTOME_RHO_GTPASE_CYCLE

DOCK4 ANKFY1 DOCK11 USP9X NCF1 ARHGEF18 LCK FAM13A NISCH ARHGEF2 DOCK6

1.31e-044399211MM15595
PathwayREACTOME_RAC1_GTPASE_CYCLE

DOCK4 DOCK11 NCF1 ARHGEF18 FAM13A NISCH DOCK6

1.45e-04175927MM15599
PathwayREACTOME_RAC1_GTPASE_CYCLE

DOCK4 DOCK11 NCF1 ARHGEF18 FAM13A NISCH DOCK6

1.98e-04184927M41809
PathwayREACTOME_IRAK4_DEFICIENCY_TLR2_4

TLR2 FGA FGB

2.04e-0418923M27464
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ANKFY1 TCF20 DOCK11 USP9X KIF21A ARHGEF18 CHD4 NEDD4 SART1 AKAP9 CELSR2 SYNJ1 OSBPL3 NISCH PRKAR2A ARHGEF2 PCM1

9.94e-089631281728671696
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DOCK4 TCF20 DOCK11 INPP5E LCK LYST NEDD4 AKAP9 FAM13A SYNJ1 OSBPL3 RNF10 USP54 ARHGEF2 DOCK6 PCM1

1.22e-078611281636931259
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

FLG PCDHGC5 KIF21A DDX42 SRP72 CAT CHD4 ARID1A LYST SART1 ZNF608 TNN MYH15 OTUD3 ZNF350 UQCRC2 ARHGEF2 FUBP3 CCDC158 FCMR

3.31e-0714421282035575683
Pubmed

SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.

ANKFY1 MARS1 USP9X SRP72 CAT PFKL SART1 AARS2 AIFM1 FGA FGB UQCRC2 FUBP3

4.16e-076071281339147351
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

ATP5IF1 DOCK11 USP9X ARID1A ARID1B AKAP9 USP54 ARHGEF2 DOCK6 FUBP3 PCM1

8.65e-074461281124255178
Pubmed

Deubiquitylase USP9X maintains centriolar satellite integrity by stabilizing pericentriolar material 1 protein.

USP9X CEP290 PCM1

9.66e-076128330584065
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ZSWIM8 SYNM USP9X KIF21A CEP290 CHD4 ARID1A BRWD3 RYR3 NEUROD2 SYNJ1 SCG2 NISCH RNF10 C1S ZNF350 USP54 PCM1

1.19e-0612851281835914814
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

TCF20 MARS1 USP9X CEP290 DDX42 CAT CHD4 PFKL SART1 RPAP1 AARS2 AIFM1 UQCRC2 ARHGEF2 FUBP3 PCM1

1.21e-0610241281624711643
Pubmed

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.

PDE4D INPP5E ARHGEF18 PFKL ARID1A PRKAR2A ARHGEF2

1.29e-06147128716959763
Pubmed

Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity.

FAT4 FAT3 FAT1

1.69e-067128322510986
Pubmed

Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.

FAT4 FAT3 FAT1

1.69e-067128316059920
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

CCDC14 DOCK4 FLG CEP290 KIF20B FAT1 AKAP9 AARS2 SYNJ1 OSBPL3 RNF10 FGB PRKAR2A

1.70e-066891281336543142
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ANKFY1 NDRG2 CRACD ARID1B AARS2 ZNF608

2.36e-06103128610574462
Pubmed

Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis.

CEP290 AKAP9 PCM1

2.69e-068128324648492
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

CCDC14 ZSWIM8 FAT4 ATP5IF1 DAB2 PFKL AIFM1 SCG2 USP54 AJUBA FUBP3 PDZD4

2.75e-066081281216713569
Pubmed

Genome-wide association study of sensory disturbances in the inferior alveolar nerve after bilateral sagittal split ramus osteotomy.

STK32B ARID1B CLEC12B

4.02e-069128323834954
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ZSWIM8 TCF20 USP9X DDX42 SRP72 CHD4 ARID1A LARP4 SART1 UQCRC2 FUBP3 PCM1

5.68e-066531281222586326
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

DOCK11 USP9X CHD4 ARID1A LARP4 ARID1B AIFM1 NISCH USP54 ARHGEF2

5.70e-064401281034244565
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DOCK4 ATP5IF1 ANKFY1 DOCK11 DDX42 ARHGEF18 CAT FAM13A NISCH PRKAR2A ARHGEF2 AJUBA DOCK6 FUBP3

7.57e-069161281432203420
Pubmed

Vti1b promotes TRPV1 sensitization during inflammatory pain.

DOCK11 DAB2 CAT AIFM1 OSBPL3 FGA

7.93e-06127128630335684
Pubmed

CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity.

CHD4 FGA FGB

1.05e-0512128327140400
Pubmed

Isoform-specific targeting of PKA to multivesicular bodies.

AKAP9 AIFM1 PRKAR2A

1.05e-0512128321502359
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

FLG TCEAL7 TCF20 ZC3H8 DDX42 SRP72 CHD4 ARID1A PCED1B SART1 ARID1B KCTD3 UQCRC2 ARHGEF2 DOCK6

1.12e-0510821281538697112
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

FLG SRP72 CHD4 SART1 FANCG AIFM1 KCTD3 UQCRC2 FUBP3 PCM1

1.15e-054771281031300519
Pubmed

Fibrinogen genotypes (alpha and beta) are associated with plasma fibrinogen levels in Chinese.

FGA FGB

1.34e-052128211546832
Pubmed

Fibrinogen and fibrin: scaffold proteins in hemostasis.

FGA FGB

1.34e-052128217414213
Pubmed

De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1.

CASP9 BCL2L1

1.34e-052128211801602
Pubmed

Congenital afibrinogenemia: Identification and characterization of two novel homozygous fibrinogen Aα and Bβ chain mutations in two Tunisian families.

FGA FGB

1.34e-052128227164460
Pubmed

Fibrinogen Houston: a dysfibrinogen exhibiting defective fibrin monomer aggregation and alpha-chain cross-linkages.

FGA FGB

1.34e-05212826165239
Pubmed

Detection of caspase-9 activation in the cell death of the Bcl-x-deficient mouse embryo nervous system by cleavage sites-directed antisera.

CASP9 BCL2L1

1.34e-052128210960682
Pubmed

Dissecting the role of SWI/SNF component ARID1B in steady-state hematopoiesis.

ARID1A ARID1B

1.34e-052128237611161
Pubmed

Subunits of ARID1 serve as novel biomarkers for the sensitivity to immune checkpoint inhibitors and prognosis of advanced non-small cell lung cancer.

ARID1A ARID1B

1.34e-052128232791957
Pubmed

Fibrinogen alpha and beta gene polymorphisms in pediatric stroke--case-control and family based study.

FGA FGB

1.34e-052128225555432
Pubmed

Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers.

ARID1A ARID1B

1.34e-052128228967863
Pubmed

Binding of Human Fibrinogen to MRP Enhances Streptococcus suis Survival in Host Blood in a αXβ2 Integrin-dependent Manner.

FGA FGB

1.34e-052128227231021
Pubmed

Fibrinogen polymorphisms are not associated with the risk of myocardial infarction.

FGA FGB

1.34e-052128211054085
Pubmed

Increased level of fibrinogen chains in the proteome of blood platelets in secondary progressive multiple sclerosis patients.

FGA FGB

1.34e-052128230838756
Pubmed

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes.

FAT4 ARID1A

1.34e-052128222484628
Pubmed

Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptive redistribution of BAF complexes.

ARID1A ARID1B

1.34e-052128234386776
Pubmed

Fibrinopeptide A release is necessary for effective B:b interactions in polymerisation of variant fibrinogens with impaired A:a interactions.

FGA FGB

1.34e-052128223238100
Pubmed

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.

ARID1A ARID1B

1.34e-052128223202128
Pubmed

ARID1 proteins: from transcriptional and post-translational regulation to carcinogenesis and potential therapeutics.

ARID1A ARID1B

1.34e-052128233890484
Pubmed

Variation of plasma D-dimer following surgery: implications for prediction of postoperative venous thromboembolism.

FGA FGB

1.34e-052128211833854
Pubmed

ARID1B is a specific vulnerability in ARID1A-mutant cancers.

ARID1A ARID1B

1.34e-052128224562383
Pubmed

[Nine polymorphisms of fibrinogen gene and their association with plasma fibrinogen levels in Hainan Han population].

FGA FGB

1.34e-052128216086292
Pubmed

Identification of a novel mutation in congenital afibrinogenemia in Iranian patients.

FGA FGB

1.34e-052128233901106
Pubmed

Streptococcus gordonii FSS2 Challisin affects fibrin clot formation by digestion of the αC region and cleavage of the N -terminal region of the Bβ chains of fibrinogen.

FGA FGB

1.34e-052128222552295
Pubmed

Genetic variation in fibrinogen; its relationship to fibrinogen levels and the risk of myocardial infarction and ischemic stroke.

FGA FGB

1.34e-052128219143925
Pubmed

The Staphylococcus aureus ArlRS two-component system is a novel regulator of agglutination and pathogenesis.

FGA FGB

1.34e-052128224367264
Pubmed

ARID1B as a Potential Therapeutic Target for ARID1A-Mutant Ovarian Clear Cell Carcinoma.

ARID1A ARID1B

1.34e-052128229890703
Pubmed

[Negative association of FGA gene 128C/G polymorphism with cerebral infarction and its effect on plasma fibrinogen in Hunan Hans].

FGA FGB

1.34e-052128220533267
Pubmed

A mitogenic action for fibrinogen mediated through intercellular adhesion molecule-1.

FGA FGB

1.34e-05212829182580
Pubmed

The endocytic adaptor protein Disabled-2 is required for cellular uptake of fibrinogen.

DAB2 FGA

1.34e-052128222705885
Pubmed

SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability.

ARID1A ARID1B

1.34e-052128224788099
Pubmed

Fibrinogen genes modify the fibrinogen response to ambient particulate matter.

FGA FGB

1.34e-052128219136375
Pubmed

Establishment and characterization of VOA1066 cells: An undifferentiated endometrial carcinoma cell line.

ARID1A ARID1B

1.34e-052128233052929
Pubmed

Fibrinogen biosynthesis. Assembly, intracellular degradation, and association with lipid synthesis and secretion.

FGA FGB

1.34e-052128211460506
Pubmed

An association between fibrinogen gene polymorphisms and diabetic peripheral neuropathy in young patients with type 1 diabetes.

FGA FGB

1.34e-052128234061326
Pubmed

Interaction Between Platelet and Fibrinogen on Clot Strength in Healthy Patients.

FGA FGB

1.34e-052128236933991
Pubmed

Nucleotide sequences of the three genes coding for human fibrinogen.

FGA FGB

1.34e-05212822102623
Pubmed

Cloning of fibrinogen genes and their cDNA.

FGA FGB

1.34e-05212826575700
Pubmed

Genetic associations between fibrinogen and cognitive performance in three Scottish cohorts.

FGA FGB

1.34e-052128221258858
Pubmed

Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas.

ARID1A ARID1B

1.34e-052128227562491
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

MARS1 INPP5E KIF21A SRP72 CHD4 BCL2L1 PFKL ARID1A ISY1 SART1 AKAP9 RNF6 ZNF608 AIFM1 PRKAR2A ARHGEF2

1.46e-0512471281627684187
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

DDX42 ARHGEF18 SRP72 PFKL SART1 RPAP1 FGA FGB ARHGEF2

1.51e-05390128917643375
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZSWIM8 FAT3 CHD4 ARID1A BRWD3 ISY1 SART1 FAT1 ARID1B ZNF608 OSBPL3 FGB USP54 CSMD1 PCM1

1.61e-0511161281531753913
Pubmed

Transcriptional programs in transient embryonic zones of the cerebral cortex defined by high-resolution mRNA sequencing.

NDRG2 NEDD4 ZNF608

1.72e-0514128321873192
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK4 DOCK11 DOCK6

1.72e-0514128312432077
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

DOCK11 MARS1 USP9X SRP72 CAT CHD4 LCK PRKAR2A DOCK6

1.80e-05399128937536630
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FAT4 DOCK11 KIF21A CEP290 PFKL CHRNB4 NEUROD2 RPAP1 AIFM1 FUBP3 ADIPOR2 MTMR9

1.87e-057361281229676528
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK4 ANKFY1 TCF20 CSMD3 NEDD4 CRACD AKAP9 RPAP1 NISCH

2.11e-05407128912693553
Pubmed

CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.

FLG SYNM MARS1 CAT LARP4 AIFM1 UQCRC2 ARHGEF2 FUBP3

2.60e-05418128935338135
Pubmed

Defining the membrane proteome of NK cells.

MARS1 USP9X CEP290 DDX42 CAT CHD4 PFKL LARP4 ITGB7 LGALS8 OSBPL3 NISCH PRKAR2A FUBP3 PCM1

2.72e-0511681281519946888
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

ATP5IF1 SYNM SRP72 CAT LARP4 AKAP9 RPAP1 AARS2 AIFM1 OSBPL3 NISCH FGA PRKAR2A UQCRC2 ARHGEF2 RAB29 FUBP3

3.62e-0514961281732877691
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ANKFY1 TCF20 MARS1 KIF21A HIP1R CAT CHD4 PFKL ARID1A LARP4 KIF20B SART1 AIFM1 UQCRC2 ARHGEF2 FUBP3

3.91e-0513531281629467282
Pubmed

Quantitative Serum Proteomic Study Reveals that Fibrinogen-Related Proteins May Participate in the Pathophysiological Process of Simple Febrile Convulsion.

FGA FGB

4.02e-053128232126779
Pubmed

Genetic and environmental determinants of fibrin structure and function: relevance to clinical disease.

FGA FGB

4.02e-053128215217804
Pubmed

Identification of two new members of the CSMD gene family.

CSMD3 CSMD1

4.02e-053128212906867
Pubmed

Genetic variation in the fibrinogen gamma gene increases the risk for deep venous thrombosis by reducing plasma fibrinogen gamma' levels.

FGA FGB

4.02e-053128216144795
Pubmed

Combined identification of ARID1A, CSMD1, and SENP3 as effective prognostic biomarkers for hepatocellular carcinoma.

ARID1A CSMD1

4.02e-053128233558447
Pubmed

A non-apoptotic role for caspase-9 in muscle differentiation.

CASP9 BCL2L1

4.02e-053128218957517
Pubmed

Ring finger protein 6 promotes breast cancer cell proliferation by stabilizing estrogen receptor alpha.

BCL2L1 RNF6

4.02e-053128228223545
Pubmed

Potential role of entactin in hemostasis. Specific interaction of entactin with fibrinogen A alpha and B beta chains.

FGA FGB

4.02e-05312821680863
Pubmed

Dynamics of expression of ARID1A and ARID1B subunits in mouse embryos and in cells during the cell cycle.

ARID1A ARID1B

4.02e-053128221647563
Pubmed

Ryanodine receptors are targeted by anti-apoptotic Bcl-XL involving its BH4 domain and Lys87 from its BH3 domain.

BCL2L1 RYR3

4.02e-053128225872771
Pubmed

Association study between variants in the fibrinogen gene cluster, fibrinogen levels and hypertension: results from the MONICA/KORA study.

FGA FGB

4.02e-053128219190816
Pubmed

Identification and characterization of novel mutations in Chinese patients with congenital fibrinogen disorders.

FGA FGB

4.02e-053128232877852
Pubmed

Two-peaked synchronization in day/night expression rhythms of the fibrinogen gene cluster in the mouse liver.

FGA FGB

4.02e-053128212750384
Pubmed

Patched dependence receptor triggers apoptosis through ubiquitination of caspase-9.

CASP9 NEDD4

4.02e-053128222679284
Pubmed

The role of betagamma and alphagamma complexes in the assembly of human fibrinogen.

FGA FGB

4.02e-05312828910396
Pubmed

The downregulation of Mcl-1 via USP9X inhibition sensitizes solid tumors to Bcl-xl inhibition.

USP9X BCL2L1

4.02e-053128223171055
Pubmed

Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes.

FAT3 FAT1

4.02e-053128215744052
Pubmed

Clinical and biological features of 3 cases of hypofibrinogenemia associated with three different mutations (gamma Ala341Thr, Bbeta Tyr326Cys and Aalpha Asp496Asn).

FGA FGB

4.02e-053128217849064
Pubmed

Fibrinogen gene variation and ischemic stroke.

FGA FGB

4.02e-053128218331453
Pubmed

Fibrinogen, COPD and mortality in a nationally representative U.S. cohort.

FGA FGB

4.02e-053128222489912
Pubmed

Fibrinogen and fibrin.

FGA FGB

4.02e-05312826383194
Pubmed

[Polymorphic variants of genes encoding interleukin-6 and fibrinogen, the risk of ischemic stroke and fibrinogen levels].

FGA FGB

4.02e-053128222642105
Pubmed

PKA and PDE4D3 anchoring to AKAP9 provides distinct regulation of cAMP signals at the centrosome.

PDE4D AKAP9

4.02e-053128222908311
Pubmed

The X-linked deubiquitinase USP9X is an integral component of centrosome.

USP9X PCM1

4.02e-053128228620049
Pubmed

Modification of the interleukin-6 response to air pollution by interleukin-6 and fibrinogen polymorphisms.

FGA FGB

4.02e-053128219750100
InteractionDCANP1 interactions

FAT4 FAT3 FAT1 CELSR2

5.42e-06191274int:DCANP1
InteractionKIAA1328 interactions

CCDC14 CEP290 CARD9 PCM1 MTMR9

6.48e-06421275int:KIAA1328
InteractionLOC254896 interactions

FAT4 FAT3 FAT1 CELSR2 NISCH

7.30e-06431275int:LOC254896
InteractionYWHAZ interactions

PDE4D DOCK11 INPP5E HIP1R ARHGEF18 CAT PFKL LCK ARID1A LYST NEDD4 CRACD AKAP9 FAM13A OSBPL3 NISCH PRKAR2A UQCRC2 USP54 ARHGEF2 AJUBA ADIPOR2 PCM1

7.56e-06131912723int:YWHAZ
InteractionC2CD4B interactions

ZSWIM8 FAT4 FAT3 FAT1 CELSR2

8.19e-06441275int:C2CD4B
InteractionCEP135 interactions

CCDC14 ATP5IF1 SYNM CEP290 SRP72 KIF20B AKAP9 CARD9 USP54 PCM1

8.89e-0627212710int:CEP135
InteractionFBXO10 interactions

PRRG1 FAT3 LARP4 CELSR2 AJUBA

9.17e-06451275int:FBXO10
InteractionCARD16 interactions

FAT4 FAT3 HERC4

2.00e-0591273int:CARD16
InteractionSIRT6 interactions

FAT4 DOCK11 USP9X FAT3 CHD4 ARID1A LARP4 FAT1 ARID1B CELSR2 AIFM1 NISCH USP54 ARHGEF2

4.27e-0562812714int:SIRT6
InteractionTIAM1 interactions

ATP5IF1 INPP5E USP9X DDX42 RYR3 NEUROD2 KCTD3 ZNF350

4.76e-052051278int:TIAM1
InteractionCCDC8 interactions

MARS1 USP9X CEP290 CAT CHD4 PFKL LCK SART1 RPAP1 AARS2 AIFM1 UQCRC2 ARHGEF2 PCM1

6.83e-0565612714int:CCDC8
InteractionKRT19 interactions

CCDC14 SYNM CEP290 CHD4 FANCG AKAP9 CARD9 USP54 PCM1

7.60e-052821279int:KRT19
GeneFamilyCadherin related

FAT4 FAT3 FAT1

8.78e-051794324
GeneFamilyFibrinogen C domain containing

TNN FGA FGB

2.88e-0425943554
CoexpressionGSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_DN

CCDC14 DOCK11 ARID1A ARID1B CELSR2 ZNF608 ST8SIA4 HERC4

5.81e-062001268M8088
CoexpressionWAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_DN

DOCK4 DOCK11 DAB2 LGALS8 NISCH

2.39e-05711265M707
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA1

DOCK4 FAT4 PDE4D ZC3H8 FAT3 KIF21A STK32B CSMD3 ZNF25 AKAP9 SCG2 CSMD1

2.59e-0558412612M39068
CoexpressionGSE20727_CTRL_VS_H2O2_TREATED_DC_DN

DOCK11 HIP1R CHD4 LYST ARHGEF2 HERC4 FCMR

4.68e-051961267M9243
CoexpressionGSE3982_NEUTROPHIL_VS_BCELL_DN

LCK LARP4 RPAP1 FGA UQCRC2 RAB29 HERC4

4.99e-051981267M5521
CoexpressionGSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_DN

ARHGEF18 NDRG2 FAT1 ARID1B RPAP1 CELSR2 AJUBA

5.15e-051991267M7319
CoexpressionGSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_DN

MARS1 SRP72 TNFRSF11A SYNJ1 NISCH ARHGEF2 ST8SIA4

5.15e-051991267M7651
CoexpressionGSE41867_DAY8_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN

ZSWIM8 ANKFY1 HIP1R ATP10A ISY1 SART1 ST6GALNAC4

5.32e-052001267M9484
CoexpressionGSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

DOCK11 NCF1 ARHGEF18 KMT2E ITGB7 LGALS8 ST8SIA4

5.32e-052001267M9136
CoexpressionCAIRO_HEPATOBLASTOMA_CLASSES_DN

ZSWIM8 FAT4 CAT LCK ATP10A C1S ADIPOR2

7.90e-052131267M12176
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FAT3 SALL4 FIGN CSMD3 RYR3 FAT1 MYH15 CSMD1

3.30e-0918412892cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FAT3 SALL4 FIGN CSMD3 RYR3 FAT1 MYH15 CSMD1

3.30e-091841289ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 FAT3 SALL4 FIGN CSMD3 RYR3 FAT1 MYH15 CSMD1

3.30e-0918412892b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell11.5-Airway-Immune-Hematopoietic,_T_Cells|Airway / Age, Tissue, Lineage and Cell class

NCF1 TNFRSF11A LCK ATP10A ITGB7 PCED1B CARD9 CLNK

9.13e-0819312887c14bc481ed38378b9e6a85f768a1e526c5997e6
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP9X KIF21A CHD4 AKAP9 SYNJ1 SCG2 NISCH PCM1

9.89e-0819512883e519cffa6144a62b06124642a14c9ff39b76554
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC3_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TNFRSF11A LCK ATP10A ITGB7 TG OSBPL3 CLNK

1.06e-0618412873e9d75af578297950e469f23fb2d28393a2feef8
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP9X KIF21A CHD4 AKAP9 SCG2 NISCH PCM1

1.57e-0619512877796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

KIF21A CAT AKAP9 FAM13A CSAD USP54 CLNK

1.68e-0619712871485933986921ff45669d9b7501c8d17050b3e97
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KIF21A CAT FAT1 AKAP9 FAM13A USP54 CLNK

1.73e-061981287285f729140b1df029c24f6ca1d2438470ac51794
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

KIF21A FAT1 AKAP9 FAM13A CSAD USP54 CLNK

1.85e-062001287e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-T_reg|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK11 LCK TG PCED1B ST8SIA4 CLNK FCMR

1.85e-06200128768589705dbc84482b6c0a1a27dd552492c4e8c3d
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

BICDL2 GARNL3 CSMD3 KCTD3 FGA MUC5AC

4.12e-061461286bb7bf20245d93c8812920dd0debbf1ed00add378
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells-T-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF18 LCK ATP10A ITGB7 PCED1B FCMR

1.02e-051711286539ea88acc6f948efdeae8b69e5c5ffaee29f1d9
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF18 LCK ATP10A ITGB7 PCED1B FCMR

1.05e-0517212860fc692be845d4225ff8b63bf9195724fc8510c2c
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells-T-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF18 LCK ATP10A ITGB7 PCED1B FCMR

1.20e-0517612869d4a4dfeebb5a8a0f3ab18c37c8ddc2cd2158575
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECM2 ZNF25 NDRG2 LYST NEDD4 PCM1

1.20e-051761286749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF18 LCK ATP10A ITGB7 PCED1B FCMR

1.20e-051761286bb41e9478373726eb460af764de0277b2d09928e
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF18 LCK ATP10A ITGB7 PCED1B FCMR

1.20e-051761286ea27e18407b8a13e8212830da859efeb8f158690
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF18 LCK ATP10A ITGB7 PCED1B FCMR

1.20e-051761286bfbab3c5b738b3b0b1540f2059d0245fbd8c0031
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BICDL2 GARNL3 NCF1 CELSR2 TLR2 CCDC158

1.20e-0517612865e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-pDC_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

GARNL3 NDRG2 ITGB7 FBXO4 CLNK RAB29

1.28e-051781286dff7a59e53a7329212689ca234931ed4a1b67eee
ToppCellLPS_only-Lymphocytic_NKT-T_cells-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF18 LCK ATP10A ITGB7 PCED1B FCMR

1.37e-051801286dcef253f2e97e4436b1b04e8a06a53ff6e64522c
ToppCellLPS_only-Lymphocytic_NKT-T_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF18 LCK ATP10A ITGB7 PCED1B FCMR

1.41e-051811286a4347ae554e6dcf03c7001a2b69332b377c7c034
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NCF1 DAB2 ATP10A CRACD TLR2 ADIPOR2

1.55e-05184128615ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NCF1 DAB2 ATP10A CRACD TLR2 ADIPOR2

1.55e-051841286bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASP9 CAT FIGN OSBPL3 TNFRSF19 AJUBA

1.69e-0518712869aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

PDE4D GARNL3 FAT3 ATP10A RYR3 PCED1B

1.75e-05188128634e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

PDE4D KMT2E ARID1B AKAP9 TNFRSF19 PCM1

1.97e-051921286916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

PDE4D KMT2E ARID1B AKAP9 TNFRSF19 PCM1

2.03e-051931286e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECM2 NDRG2 NEDD4 AKAP9 C1S PCM1

2.15e-0519512865c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellhealthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

SYNM KIF21A LCK ITGB7 RAB29 PDZD4

2.21e-051961286af00c31612e4fe068e5fccae05368edba46bbd20
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE4D KIF21A LCK KIF20B PCED1B FCMR

2.21e-051961286c9fb81a0578db6d278b8582d7b3add6c407e6dcf
ToppCellControl_saline-Epithelial_alveolar-AT_2-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

BICDL2 KIF21A FAT1 AKAP9 CSAD USP54

2.27e-05197128644a59dfb889577b3160a5b13ada1276771a00241
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK11 NCF1 PCED1B OSBPL3 CLNK FCMR

2.34e-051981286824461cf44098440ba8bc0df96735423ac65bda1
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

KIF21A CEP290 SALL4 OSBPL3 CSAD USP54

2.47e-0520012862dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellParenchyma_Control_(B.)-Immune-TX-MoAM-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

SIGLEC8 DAB2 TNFRSF11A TLR2 FES ST8SIA4

2.47e-052001286670ef1e68be0d2c6ea20ab4dea1d051a3cc89799
ToppCellLPS-IL1RA-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BICDL2 INPP5E SALL4 ODAD4 AJUBA

3.32e-0512712856b24630978eb0772b4cd3bf59e5bc4390be47619
ToppCelldroplet-Liver-hepatocytes-3m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAT NDRG2 FGA FGB C1S

6.66e-05147128500619115b9a1ec2b967c2992043b41974ece63c4
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCF1 ARHGEF18 WDR27 ITGB7 FES

7.10e-0514912855a5e9660f7d9b527f50a92d94d4c0c8aedb82c0b
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCF1 LYST ITGB7 BRWD3 CCDC158

7.10e-05149128548fca6ae33d7722c024b43ce04f4dbce7b6b424b
ToppCellfacs-Lung-3m-Hematologic-Lymphocytic_NK_ILC|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF18 LCK ITGB7 OSBPL3 CLNK

7.33e-0515012851f83e3be3f94aefe991a3ccd292c2d11ddef858e
ToppCellfacs-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF18 LCK ITGB7 OSBPL3 CLNK

7.33e-051501285cd666db614bc1b43d71e8eb7bf38cae4d580be80
ToppCellfacs-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF18 LCK ITGB7 OSBPL3 CLNK

7.33e-051501285f6ed3e7b36014d1e429b255b0027d89865e1ac07
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Trm_Tgd|Liver / Manually curated celltypes from each tissue

ECM2 PCED1B CSAD CLNK DOCK6

8.30e-051541285c6308074468235c88ef4ea43ab155d9f86cbf261
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

ECM2 STK32B ATP10A TNN CSMD1

8.30e-051541285511923b27469ea20f8bd82a9ec27119a6e884644
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAT3 NCF1 ATP10A LYST OSBPL3

9.09e-0515712858c42af7aa1f1b6f4fe2f8d00a8b4a800f121e804
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAT3 NCF1 ATP10A LYST OSBPL3

9.09e-051571285ee1be3c756b72fceac6b4ccb416dd4bd031a2193
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAT3 NCF1 ATP10A LYST OSBPL3

9.09e-051571285008f938a338f43c3251dcac574f1b4f689926c71
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE4D STK32B CSMD3 C1S OTUD3

9.37e-0515812856d2709b387945c015faa223c20d22b52a4082140
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLG TCEAL7 FAT3 SCG2 TNFRSF19

9.37e-051581285e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 RYR3 C1S MYH15 ABCC12

9.94e-051601285c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF18 LCK ITGB7 OSBPL3 CLNK

9.94e-051601285e4516b093003275084fc327d1597394a436754eb
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LCK ITGB7 TG FGB CLNK

9.94e-0516012856b0faaa371650563f585722f5b2fb319e124ec38
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 RYR3 C1S MYH15 ABCC12

9.94e-05160128525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF18 LCK ITGB7 OSBPL3 CLNK

9.94e-0516012850a507e3d59d7f744d0201a531ea84fa97a68aedb
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TNFRSF11A NISCH FES ST8SIA4

1.01e-04841284013cf97d08d0adb3697cf2a146ff5ca13c676f64
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KIF21A CEP290 LCK KIF20B PCED1B

1.02e-041611285d72c572613f8eff3251cb7b1e9dcc76d193b2f21
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAT NDRG2 FGA FGB C1S

1.02e-041611285274838cebdc7af1db32d309dfe42ef7ccd3c190b
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-TRGV2_gdT|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LCK ATP10A ITGB7 FES CLNK

1.08e-041631285004765e016c5658ee4a8bda4899804303064727b
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE4D LCK BRWD3 PCED1B PDZD4

1.08e-0416312854af92b211d12c5b88b65bb746242cd702b545bd0
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE4D LCK BRWD3 PCED1B PDZD4

1.08e-041631285d24774e0aa612322c22fdb3b314aef275fa01d68
ToppCelldroplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCDHGC5 NCF1 FES ST8SIA4 PDZD4

1.12e-041641285cfe07a1ebed8aecb08d0476db71fe314998d54aa
ToppCelldroplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCDHGC5 NCF1 FES ST8SIA4 PDZD4

1.12e-0416412856d331e74efecb4733d87653f86cd67247be05025
ToppCellCOPD-Myeloid-DC_Langerhans|Myeloid / Disease state, Lineage and Cell class

NDRG2 TTLL2 SCG2 ST8SIA4 CLNK

1.12e-041641285a07c6e13c07a90bc37db0915eb14931eb8309a1e
ToppCellMild-Lymphoid-NK-CD8_T|Mild / Condition, Lineage, Cell class and cell subclass

KIF21A LCK KMT2E ITGB7 CLNK

1.15e-0416512859b0b037383e3e7cf7cfbc65b8d4c4721be3210f8
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB7 CHRNB4 TG TNFRSF19 FCMR

1.15e-04165128536415924d05373e9dd3665be599f4f3f40bf0497
ToppCellfacs-Kidney-nan-3m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 LCK ITGB7 RYR3 PCED1B

1.15e-041651285ba041deb0d9c187f251493ccd4794b5f09abd5aa
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB7 CHRNB4 TG TNFRSF19 FCMR

1.15e-04165128556310fddd3d8e4afdfde066d26cee9747e5b8c6a
ToppCellcontrol-Epithelial-Ionocyte|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DOCK4 FAT3 SCG2 CLNK DOCK6

1.15e-0416512855cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

CHD4 KMT2E ARID1A ARID1B ZNF608

1.18e-04166128532d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 NCF1 CARD9 TLR2 FES

1.18e-04166128582fa07632f7e586698fbf37381715b40f9f6ae3a
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 NCF1 CARD9 TLR2 FES

1.18e-0416612850d03926452414f232c77fd15d5f48d148f9fca3b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LCK KMT2E CSMD3 NDRG2 SART1

1.21e-0416712853b717d33aaf1ef0869cc4bca8432ba8008875cc5
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRRG1 FAT4 ABCB6 WDR27 C1S

1.21e-041671285b742558ca92985db0a67c88f530bc375f3d3bb98
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC14 FAT3 HIP1R ZNF608 CSMD1

1.25e-0416812858072d0496b7b730c4601009eaa69ec5366d26d73
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCK ITGB7 TG OSBPL3 CLNK

1.25e-0416812851254c66f0cd53ef3b913933c0b0648d091da07e9
ToppCellfacs-Spleen-nan-3m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCL2L1 LCK ATP10A OSBPL3 CLNK

1.25e-04168128574dc46738f1d0a448df6c9b8288b515d92697792
ToppCellfacs-Skin-Skin_Anagen-18m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCF1 LCK ITGB7 ST8SIA4 CLNK

1.28e-041691285630d921aa8fb5681d06a4e09b833855c374be484
ToppCellfacs-Skin-Skin_Anagen-18m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCF1 LCK ITGB7 ST8SIA4 CLNK

1.28e-041691285468284d4a3a0557aed04eadb1aba2317babc6904
ToppCellfacs-Skin-Skin_Anagen-18m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCF1 LCK ITGB7 ST8SIA4 CLNK

1.28e-0416912856f765e142d127545e622fe24b5287cd6e9706ccc
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAT4 PDE4D STK32B DAB2 C1S

1.28e-041691285c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF18 LCK OSBPL3 USP54 FCMR

1.28e-041691285d721dbb317a88113b4f76688111908d00f23e899
ToppCellBL-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FAT4 GARNL3 FIGN SCG2 CLNK

1.32e-041701285b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium|TCGA-Endometrium / Sample_Type by Project: Shred V9

TCEAL7 GARNL3 SYNM ECM2 RYR3

1.32e-041701285cdc19013da7c41d1ed8400a6a643e4c684ff9912
ToppCellTCGA-Endometrium-Solid_Tissue_Normal|TCGA-Endometrium / Sample_Type by Project: Shred V9

TCEAL7 GARNL3 SYNM ECM2 RYR3

1.32e-0417012850bde0a40440c7fdf7ba89cac8831d4014e7a4807
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE4D DOCK11 ARHGEF18 LCK KIF20B

1.32e-0417012853ad9f950b87ee98f025ab9b4a8ed551e6a9b4764
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue|TCGA-Endometrium / Sample_Type by Project: Shred V9

TCEAL7 GARNL3 SYNM ECM2 RYR3

1.32e-041701285516b38c4ecf6b0b04c5d4f80c510dcc00b328c6f
ToppCellmetastatic_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

DOCK4 BICDL2 GARNL3 NCF1 AARS2

1.39e-041721285c3822ff7329c3ac38c68c5c38cd67c390682e2a6
ToppCellcontrol-Myeloid-Mast_cell|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DOCK11 SIGLEC8 NCF1 SCG2 CLNK

1.39e-041721285c1c99e6732234a6649a79610e99390db0c8f19b0
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCF1 ITGB7 NEDD4 AARS2 PDZD4

1.43e-0417312853612772632ddf11eb48579cae9a8ccab6b3f1f52
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCF1 ITGB7 NEDD4 AARS2 PDZD4

1.43e-0417312854dc261ebcdb9bdcfca1451da1bd254f0dc5de203
ToppCellInt-URO-Lymphocyte-T_NK-NK_CD56bright|Int-URO / Disease, Lineage and Cell Type

FAT3 SALL4 TNFRSF11A LCK CCDC158

1.47e-04174128593c7acd5941a5f235ec4c57461f78ee2871e7336
ToppCellfacs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NCF1 TNFRSF11A ITGB7 FES CLNK

1.47e-0417412856688424fc4e40c3c4a89669a2bc79369a726f1e6
ToppCellNS-control-d_0-4-Myeloid-Mast_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DOCK11 SIGLEC8 NCF1 SCG2 CLNK

1.47e-0417412852d1f5c17b1551f32f49618ec1bf68eafbfd02ace
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT3 TNFRSF11A SCG2 ST8SIA4 HERC4

1.51e-0417512851ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSMD3 SCG2 MYH15 CSMD1 FCMR

1.51e-041751285887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LCK ATP10A ITGB7 FES CLNK

1.55e-041761285dbc4f64cd39b229f2355ca1d0215cc7f6a767dce
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NCF1 ITGB7 ST8SIA4 CLNK TTLL13

1.55e-0417612855f8c1f917fba49f3b1c0d88b946eca242b668fde
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NCF1 DAB2 CRACD TLR2 ADIPOR2

1.55e-041761285e74ad0db3b05897edcfabeb11008ede2b9eeb638
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-SELL+_CD4_T|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LCK ATP10A ITGB7 CLNK FCMR

1.59e-0417712857d73643beb007032e757f2611121c4f3027aecf5
DrugHesperidin [520-26-3]; Up 200; 6.6uM; MCF7; HT_HG-U133A

CASP9 BCL2L1 LYST AKAP9 RPAP1 RNF6 ST6GALNAC4 HERC4 PCM1

1.53e-0619512795313_UP
DrugAmitrole

ABCB6 CASP9 CAT TG MUC5AC

4.05e-06431275ctd:D000640
Drug2-amino-4,5-diphenylthiazole

SYNM CAT MUC5AC

5.84e-0671273CID000073222
Drug1-methyl-2-nitro-1-nitrosoguanidine

SYNM CASP9 CAT CHD4 ITGB7 LGALS8 TG AIFM1 FES

7.79e-062381279CID000006261
DrugThymol

CASP9 CAT BCL2L1 AIFM1

1.25e-05261274ctd:D013943
DrugChlorpropamide [94-20-2]; Down 200; 14.4uM; HL60; HG-U133A

PRRG1 LYST LGALS8 RPAP1 CARD9 CSAD FES PRKAR2A

1.69e-0520012781594_DN
DrugZithromac

BCL2L1 LYST CSAD FGA FGB MUC5AC

1.96e-05991276CID000002269
Drugtetraglyme

FGA FGB C1S

1.98e-05101273CID000008925
DiseaseSquamous cell carcinoma of esophagus

FAT4 FAT3 SALL4 FAT1 RNF6 AJUBA

3.59e-06951276C0279626
DiseaseHereditary factor I deficiency disease

FGA FGB

5.50e-0531272cv:C0019250
DiseaseFamilial dysfibrinogenemia

FGA FGB

5.50e-0531272cv:C0272350
DiseaseCongenital afibrinogenemia

FGA FGB

5.50e-0531272cv:C2584774
DiseaseAFIBRINOGENEMIA, CONGENITAL

FGA FGB

5.50e-0531272202400
Diseasecongenital afibrinogenemia (is_implicated_in)

FGA FGB

5.50e-0531272DOID:2236 (is_implicated_in)
DiseaseHashimoto Disease

TG C1S

5.50e-0531272C0677607
DiseaseDYSFIBRINOGENEMIA, CONGENITAL

FGA FGB

5.50e-0531272616004
Diseasekeratoconjunctivitis (is_marker_for)

TLR2 MUC5AC

5.50e-0531272DOID:9368 (is_marker_for)
DiseaseDysfibrinogenemia, Congenital

FGA FGB

5.50e-0531272C0272350
Diseasesunburn

FLG PDE4D CEP290 ARID1B FAM13A

6.10e-05961275EFO_0003958
Diseasebacterial pneumonia (implicated_via_orthology)

CAT TLR2

1.10e-0441272DOID:874 (implicated_via_orthology)
Diseaseacne (is_marker_for)

CAT TLR2

1.10e-0441272DOID:6543 (is_marker_for)
DiseaseAfibrinogenemia

FGA FGB

1.10e-0441272C0001733
DiseaseCongenital hypofibrinogenemia

FGA FGB

1.10e-0441272C2584774
DiseaseFibrinogen Deficiency

FGA FGB

1.82e-0451272C4316812
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

ARID1A ARID1B

1.82e-0451272C3281201
Diseaselung non-small cell carcinoma (is_implicated_in)

CASP9 ARID1A CHRNB4 FAT1 ARID1B

3.46e-041391275DOID:3908 (is_implicated_in)
Diseasecatalase measurement

CAT CELSR2

3.81e-0471272EFO_0008071
Diseasestomach cancer (is_marker_for)

CASP9 BCL2L1 TNFRSF11A ARID1A DOCK6

3.82e-041421275DOID:10534 (is_marker_for)
Diseaseresponse to radiation

ATP10A ITGB7 BRWD3 CSMD1

5.77e-04881274GO_0009314
Diseasepancreatitis (biomarker_via_orthology)

TLR2 FGA FGB

6.35e-04391273DOID:4989 (biomarker_via_orthology)
DiseaseRetinal Pigment Epithelial Detachment

CASP9 AIFM1

6.49e-0491272C0339546
Diseasepost-operative sensory disturbance

STK32B CLEC12B

6.49e-0491272EFO_0005324
Diseasecutaneous leishmaniasis (is_marker_for)

CAT TLR2

8.09e-04101272DOID:9111 (is_marker_for)
DiseaseCarotid Circulation Transient Ischemic Attack

CASP9 NDRG2

8.09e-04101272C0751019
DiseaseTransient Ischemic Attack

CASP9 NDRG2

8.09e-04101272C0007787
Diseaseneuroblastoma (is_implicated_in)

ARID1A ARID1B

8.09e-04101272DOID:769 (is_implicated_in)
DiseaseCrescendo Transient Ischemic Attacks

CASP9 NDRG2

8.09e-04101272C0751021
DiseaseTransient Ischemic Attack, Vertebrobasilar Circulation

CASP9 NDRG2

8.09e-04101272C0751020
DiseaseBrain Stem Ischemia, Transient

CASP9 NDRG2

8.09e-04101272C0751022
Diseasevitamin B6 measurement

ZNF608 OSBPL3

8.09e-04101272EFO_0004621
DiseasePosterior Circulation Transient Ischemic Attack

CASP9 NDRG2

8.09e-04101272C0472381
DiseaseTransient Ischemic Attack, Anterior Circulation

CASP9 NDRG2

8.09e-04101272C1527335
DiseaseTransient Cerebral Ischemia

CASP9 NDRG2

8.09e-04101272C0917805
Diseasedry eye syndrome (is_marker_for)

TLR2 MUC5AC

8.09e-04101272DOID:10140 (is_marker_for)
Diseasechronic obstructive pulmonary disease, chronic bronchitis

FAM13A CSMD1

8.09e-04101272EFO_0000341, EFO_0006505
DiseaseMalignant Head and Neck Neoplasm

BCL2L1 FANCG FAT1

9.06e-04441273C0278996
DiseaseColorectal Carcinoma

ABCB6 ARID1A CSMD3 FANCG FAT1 AKAP9 RPAP1 TLR2 UQCRC2 ST8SIA4

9.40e-0470212710C0009402
DiseaseAutistic Disorder

DOCK4 CAT CHD4 KMT2E CSMD3 ATP10A

9.58e-042611276C0004352
DiseaseRetinal Detachment

CASP9 AIFM1

9.86e-04111272C0035305
Diseasehepatocellular carcinoma (is_implicated_in)

CAT ARID1A RYR3 TLR2 FES

1.14e-031811275DOID:684 (is_implicated_in)
DiseasePulmonary Thromboembolisms

CAT FGA

1.18e-03121272C0524702
DiseasePulmonary Embolism

CAT FGA

1.18e-03121272C0034065
Diseasepulmonary embolism (biomarker_via_orthology)

FGA FGB

1.18e-03121272DOID:9477 (biomarker_via_orthology)
Diseaselung adenocarcinoma (is_implicated_in)

CHD4 CHRNB4 FES

1.24e-03491273DOID:3910 (is_implicated_in)
DiseaseStreptozotocin Diabetes

NCF1 CAT BCL2L1 AIFM1

1.24e-031081274C0038433
DiseaseDiabetes Mellitus, Experimental

NCF1 CAT BCL2L1 AIFM1

1.24e-031081274C0011853
DiseaseAlloxan Diabetes

NCF1 CAT BCL2L1 AIFM1

1.24e-031081274C0002152
Diseasecognitive function measurement

ANKFY1 PDE4D TCF20 STK32B KMT2E FIGN CSMD3 RYR3 ARID1B ZNF608 TTLL2 RNF10 MYH15 CLNK AJUBA

1.31e-03143412715EFO_0008354
DiseaseCholestasis

SRP72 CAT TLR2 FGA

1.33e-031101274C0008370
Diseaselung disease (implicated_via_orthology)

CAT TLR2

1.39e-03131272DOID:850 (implicated_via_orthology)
Diseasecataract (biomarker_via_orthology)

CASP9 CAT

1.39e-03131272DOID:83 (biomarker_via_orthology)
DiseaseCoffin-Siris syndrome

ARID1A ARID1B

1.39e-03131272C0265338
Diseasegastric ulcer (implicated_via_orthology)

BCL2L1 MUC5AC

1.62e-03141272DOID:10808 (implicated_via_orthology)
DiseaseAlzheimer disease, visuospatial impairment

AARS2 CSMD1

1.62e-03141272EFO_0009752, MONDO_0004975
Diseaseperipheral arterial disease

CSMD3 CHRNB4 CELSR2

1.65e-03541273EFO_0004265
DiseasePolydactyly

INPP5E USP9X CEP290 SALL4

1.67e-031171274C0152427
Diseasetriacylglycerol 52:2 measurement

TG CARD9 CSMD1

1.73e-03551273EFO_0010414
Diseasephospholipids in medium HDL measurement

ARID1A CELSR2 DOCK6

1.73e-03551273EFO_0022295
DiseaseIschemic stroke, tissue plasminogen activator measurement

FGA FGB

1.86e-03151272EFO_0004791, HP_0002140
DiseaseGraves' disease (is_marker_for)

CAT TG

1.86e-03151272DOID:12361 (is_marker_for)
Diseasecolorectal cancer (is_implicated_in)

CASP9 CHD4 FAT1 TLR2

1.89e-031211274DOID:9256 (is_implicated_in)
Diseasetotal lipids in medium HDL measurement

ARID1A CELSR2 DOCK6

2.02e-03581273EFO_0022310
DiseaseIschemic stroke, plasminogen activator inhibitor 1 measurement

FGA FGB

2.12e-03161272EFO_0004792, HP_0002140
Diseaseangina pectoris

FIGN BRWD3 CELSR2 FES

2.12e-031251274EFO_0003913
Diseasecholesterol in medium HDL measurement

ARID1A CELSR2 DOCK6

2.12e-03591273EFO_0021903
Diseasephospholipids in HDL measurement

ARID1A CELSR2 DOCK6

2.34e-03611273EFO_0022293
Diseaseotitis media (biomarker_via_orthology)

CAT MUC5AC

2.40e-03171272DOID:10754 (biomarker_via_orthology)
Diseasefactor XI measurement, Ischemic stroke

FGA FGB

2.40e-03171272EFO_0004694, HP_0002140
Diseasetuberculosis

KIF21A FIGN NEDD4 PCED1B CSMD1

2.48e-032161275MONDO_0018076
Diseasecarcinoma (implicated_via_orthology)

FAT4 SALL4 LCK

2.68e-03641273DOID:305 (implicated_via_orthology)
Diseaseinterstitial lung disease

FAM13A CSMD1 MUC5AC

3.05e-03671273EFO_0004244
Diseasejoint damage measurement

TG CARD9 CSMD1

3.18e-03681273EFO_0005413
DiseaseFamilial aplasia of the vermis

INPP5E CEP290

3.32e-03201272cv:C0431399
DiseaseLupus Erythematosus, Systemic

NCF1 CAT C1S

3.60e-03711273C0024141
Diseasevitiligo (is_implicated_in)

CAT TLR2

3.66e-03211272DOID:12306 (is_implicated_in)
Diseasegastric ulcer (biomarker_via_orthology)

CAT MUC5AC

3.66e-03211272DOID:10808 (biomarker_via_orthology)
Diseasedilated cardiomyopathy (biomarker_via_orthology)

CASP9 BCL2L1

4.01e-03221272DOID:12930 (biomarker_via_orthology)
Diseaselymphocyte count, response to vaccine

TEKT3 OSBPL3

4.01e-03221272EFO_0004587, EFO_0004645
Diseaseotitis media (implicated_via_orthology)

SALL4 NISCH

4.01e-03221272DOID:10754 (implicated_via_orthology)
Diseaselung disease (is_implicated_in)

CAT TLR2

4.01e-03221272DOID:850 (is_implicated_in)
Diseaserespiratory symptom measurement, COVID-19

BRWD3 FAT1 CSMD1

4.04e-03741273EFO_0007939, MONDO_0100096
Diseaseneuritic plaque measurement

KIF21A RYR3 ZNF608 MYH15 ARHGEF2 CSMD1

4.09e-033491276EFO_0006798

Protein segments in the cluster

PeptideGeneStartEntry
SSGRFRQDVQEALEG

CHRNB4

416

P30926
DNSSRFSLNGGANIE

AKAP9

3631

Q99996
GDLLVQQFSGENGER

ARHGEF18

531

Q6ZSZ5
ENGRRAGSDFRVGAN

CSMD1

356

Q96PZ7
INARRFGDNFQLGSS

CSMD3

841

Q7Z407
SGEVRRFNTANDDNV

CAT

426

P04040
SDFGGFRVNAELQAR

AIFM1

416

O95831
EQGSLDAERNQRGSF

AJUBA

66

Q96IF1
RADSDSSQRDRNGNQ

ARHGEF2

716

Q92974
RHNEGDDQQGSRYSV

FBXO4

261

Q9UKT5
GNTNQEFRIDSVTGA

FAT4

2196

Q6V0I7
ADNIRYGRVTAGNDE

ABCB6

681

Q9NP58
GNNAAAESRKGQERF

BCL2L1

196

Q07817
NQGRRTVLYNDDSDN

BRWD3

1751

Q6RI45
DRSDKLGRVQEFNSG

ARID1B

1871

Q8NFD5
FAERLQRNESGLDSG

CELSR2

2036

Q9HCU4
QRNESGLDSGRSQQL

CELSR2

2041

Q9HCU4
SASRQTRNEEQSGDG

FLG

566

P20930
SRQTRNEEQSGDGSR

FLG

1541

P20930
SRQTRNDEQSGDGSR

FLG

3486

P20930
RQGEEDRENTTGSDN

CARD9

516

Q9H257
TSRDEQDFRNGLAAL

CCDC14

921

Q49A88
FSRTEQLADGQAGRG

ATP10A

1456

O60312
DDALEGSASNTQGRQ

NBPF4

571

Q96M43
QLDGTRRGDNDSHQG

ADIPOR2

26

Q86V24
ANYRGGEIREQNGDS

UQCRC2

251

P22695
RDQIDRFSKENGFTG

RAB29

136

O14966
RSNSVGIQDAFNDGS

ARID1A

1181

O14497
EFGANVNAQDAEGRT

ANKFY1

791

Q9P2R3
RTQNGVSEREQNGFS

DAB2

376

P98082
PSDSRNNLDRNSFEG

FAT1

4261

Q14517
ISNTNRGNGFDRSAE

FIGN

356

Q5HY92
VFNAGSDERANSRDE

MAGEB5

6

Q9BZ81
GNEGKVDNLSRDSNR

NEDD4

491

P46934
FRGSQEDLEARNGTS

INPP5E

96

Q9NRR6
SDADRFQVDLQNGSS

LGALS8

41

O00214
ASQFGTFLGNNESER

MTMR9

431

Q96QG7
QNAGLGEFRIRDLND

ISY1

61

Q9ULR0
FNQRGTRLASSGDDL

DCAF8L2

236

P0C7V8
GANDGRNGESRKEAF

DDX42

876

Q86XP3
QGVNDNEEGFFSARG

FGB

31

P02675
DLDQRSIGSDSQGRA

PCM1

111

Q15154
LFNVRDRDSGRNGEV

PCDHGC5

371

Q9Y5F6
SGGNSALDVNRNESL

PDZD4

381

Q76G19
RFDEATQLRGGSFEN

PFKL

366

P17858
SFQGLRRFDVDNGTS

PDE4D

146

Q08499
GQLRARGELNFEQDE

PCED1B

46

Q96HM7
FDGQRAAENRQGTLT

NCF1

81

P14598
RNKFGQLGLNDENDR

HERC4

216

Q5GLZ8
DQADFRGVRGDFNSR

FUBP3

236

Q96I24
QNEGERLRETGNINT

KIF20B

391

Q96Q89
SGFGRTVNDNLIDGN

KMT2E

1131

Q8IZD2
GSFSLSVRDFDQNQG

LCK

161

P06239
GINGGDFDTFQNLRD

MUC5AC

1596

P98088
RASLAQGFTEDQAQD

FANCG

81

O15287
FQDGRNDVQESSLRD

FAM13A

141

O94988
TGDAQAFEREVGRQS

ITGB7

236

P26010
AFEREVGRQSVSGNL

ITGB7

241

P26010
RIFGNQGLNEGRTEN

OTUD3

306

Q5T2D3
SSQEQGELQGRLAER

HIP1R

591

O75146
GDGRQNLFSFDSEVQ

DOCK11

331

Q5JSL3
RRLFSLATGGQNEEE

DOCK4

716

Q8N1I0
RQVFEQDASGDERSG

DOCK6

151

Q96HP0
ERRGFSEGGRQNFDV

C4orf3

16

Q8WVX3
AQQSAGGRDTRFLRN

CEP290

101

O15078
EDIQRAGSGSRRDQA

CASP9

41

P55211
RREQQGRSGDFQGAD

CRACD

461

Q6ZU35
NGNFALRITATDGEN

FAT3

646

Q8TDW7
NLRGSGDGRNVYQEV

FAT3

4211

Q8TDW7
DTEEGRLCGQRSSNN

C1S

76

P09871
QLGEQRSEQQDSGRE

BICDL2

131

A1A5D9
AQGDQGLERRIDQAF

CSAD

371

Q9Y600
LNDRNEFSGDSSEQR

ECM2

171

O94769
NREGFDFGVRQNGER

LYST

3306

Q99698
EILRGDFSSANNRDN

FGA

111

P02671
STLQVEQNGDYGRGR

LARP4

431

Q71RC2
DNQTRSVGQYDNRGS

PRKAR2A

191

P13861
ARTERDQFSQESGNL

CCDC158

361

Q5M9N0
QARGFGSDQSENVDR

ATP5IF1

21

Q9UII2
TRNFEALNARGGGNQ

CHD4

991

Q14839
TGREAVENVNFRSLG

RSC1A1

436

Q92681
FNLQRQGSRENGSVE

SALL4

741

Q9UJQ4
ADSRNGLNSTEGEAR

KCTD3

146

Q9Y597
AGRFRVENGSSDENA

GARNL3

61

Q5VVW2
SGDNLAEENSRDENR

OSBPL3

416

Q9H4L5
NFGEVFSGRLRADNT

FES

571

P07332
RTGQRAQENYEGSEE

USP9X

2531

Q93008
RDADSRNDQAVGVSF

SYNM

1491

O15061
RAGTRFNVRGTNDDG

SYNJ1

211

O43426
SYNNRRDLNFERGGD

NDRG2

236

Q9UN36
DDALEGSASNTQGRQ

NBPF6

571

Q5VWK0
NRENQSILFTGESGA

MYH15

186

Q9Y2K3
SGELEQRLSGEFSRQ

ODAD4

616

Q96NG3
LQNGQNGERATRLFE

SCG2

326

P13521
QSGGSELRQREGQRF

RNF6

261

Q9Y252
RDEGEFTCRAQNAQG

SIGLEC8

321

Q9NYZ4
QRAFGGFRNESDREK

ST8SIA4

196

Q92187
DTTQNLGERVNDIGF

TEKT3

141

Q9BXF9
SEVNRYGQNGDFTRA

SRP72

16

O76094
TENGENFSVGERQLL

ABCC12

1251

Q96J65
RTNFYAEQGGQASDR

AARS2

561

Q5JTZ9
QASDRGYLVRAGQED

AARS2

571

Q5JTZ9
RNQQFALGTGLRGDE

CLNK

366

Q7Z7G1
TFQDSAGARNNRDGN

CLEC12B

11

Q2HXU8
GEFERQQTEGNFRQR

TCEAL7

26

Q9BRU2
FQDETGKNRRQSGSF

ST6GALNAC4

196

Q9H4F1
LQGDNRSYSQEGSRE

TEX13D

591

A0A0J9YY54
REDQRFALQGLEQGA

TNN

1021

Q9UQP3
IQGDNLFSGSRDNGI

KIF21A

1551

Q7Z4S6
ADDQAFVFEGNRGQR

RYR3

1116

Q15413
FNGGRRDEVAEAQRA

RNF10

111

Q8N5U6
QRALDYGSQSGREGQ

FCMR

236

O60667
SFADGQPAERRASND

NISCH

1026

Q9Y2I1
YLNGLRNEGREASNA

TTLL2

416

Q9BWV7
EESSRNGAEQGRQLS

STH

81

Q8IWL8
KLEERGANQDSRNGS

STIMATE

226

Q86TL2
QVISRAQAGEFGDRL

RPAP1

416

Q9BWH6
SSEDQGERVRQLSGQ

TCF20

526

Q9UGU0
LGDQTQDGDFGSRLR

SART1

426

O43290
ASGDNRGFAQDRNLV

ZNF350

496

Q9GZX5
ANGFFEEIRQGNIER

PRRG1

21

O14668
LANGSADEFQRGDQL

ZSWIM8

126

A7E2V4
RYQESQAGNSRNGEL

ZNF25

91

P17030
SGDCRQQEFRDRSGN

TNFRSF19

31

Q9NS68
NEGLANGLSESQESR

ZNF608

861

Q9ULD9
RRQQGQGSQLLDTDS

STK32B

371

Q9NY57
AGRNRTVEVFDLNAG

WDR27

676

A2RRH5
GVGNFRASDNDRVID

TLR2

291

O60603
QALQNSLGGEDSDAR

TG

2541

P01266
ENDQIESLRQRFGGG

MARS1

806

P56192
QEETLARRDSFAGNG

TNFRSF11A

571

Q9Y6Q6
LDELQNQGRSDGFER

USP54

781

Q70EL1
NQGRSDGFERSLQEA

USP54

786

Q70EL1
ARDQNQGESAGEKSR

TTLL13

536

A6NNM8
SNALLRNSGSQEEDG

ZC3H8

156

Q8N5P1
NSRNFLTEQGADGAG

NEUROD2

211

Q15784