Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionNotch binding

JAG2 DLL1 JAG1

8.74e-0627303GO:0005112
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN8A

1.96e-0414302GO:0031402
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN1A SCN8A

6.93e-0426302GO:0005248
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN8A

6.93e-0426302GO:0031420
GeneOntologyMolecularFunctioncalcium ion binding

JAG2 LRP2 DLL1 NRXN1 JAG1 SLIT1

7.50e-04749306GO:0005509
GeneOntologyMolecularFunctionmolecular function activator activity

JAG2 ALS2 LTF PSAP DLL1 CXCL17 JAG1

1.95e-031233307GO:0140677
GeneOntologyMolecularFunctionlipopolysaccharide binding

LTF ADGRB1

2.36e-0348302GO:0001530
GeneOntologyMolecularFunctionsodium channel activity

SCN1A SCN8A

2.76e-0352302GO:0005272
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

KCNMA1 JAG2 LRP2 PSAP SCN1A SCN8A

8.43e-07238296GO:0050954
GeneOntologyBiologicalProcesswalking behavior

KCNMA1 PSAP SCN1A SCN8A

1.45e-0660294GO:0090659
GeneOntologyBiologicalProcessinner ear auditory receptor cell differentiation

KCNMA1 JAG2 DLL1 JAG1

2.27e-0667294GO:0042491
GeneOntologyBiologicalProcesslocomotory behavior

KCNMA1 ALS2 PSAP GRM1 SCN1A SCN8A

2.35e-06284296GO:0007626
GeneOntologyBiologicalProcesshair cell differentiation

KCNMA1 JAG2 DLL1 JAG1

4.18e-0678294GO:0035315
GeneOntologyBiologicalProcessnegative regulation of response to external stimulus

CYLD FXR1 LTF FGG NRXN1 CXCL17 SLIT1

5.21e-06509297GO:0032102
GeneOntologyBiologicalProcesssensory perception of sound

KCNMA1 JAG2 LRP2 PSAP SCN8A

7.63e-06198295GO:0007605
GeneOntologyBiologicalProcessinner ear receptor cell differentiation

KCNMA1 JAG2 DLL1 JAG1

9.57e-0696294GO:0060113
GeneOntologyBiologicalProcessmechanoreceptor differentiation

KCNMA1 JAG2 DLL1 JAG1

1.31e-05104294GO:0042490
GeneOntologyBiologicalProcesscerebellar cortex formation

PSAP DLL1 NRXN1

1.45e-0534293GO:0021697
GeneOntologyBiologicalProcessbehavior

KCNMA1 ALS2 FXR1 PSAP GRM1 NRXN1 SCN1A SCN8A

2.24e-05891298GO:0007610
GeneOntologyBiologicalProcessinner ear development

KCNMA1 JAG2 PSAP DLL1 JAG1

2.49e-05253295GO:0048839
GeneOntologyBiologicalProcessinner ear receptor cell fate commitment

JAG2 DLL1

2.85e-056292GO:0060120
GeneOntologyBiologicalProcesspulmonary artery morphogenesis

LRP2 JAG1

2.85e-056292GO:0061156
GeneOntologyBiologicalProcessauditory receptor cell fate commitment

JAG2 DLL1

2.85e-056292GO:0009912
GeneOntologyBiologicalProcessinhibition of neuroepithelial cell differentiation

DLL1 JAG1

2.85e-056292GO:0002085
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

ALS2 FXR1 GRM1 NRXN1

3.36e-05132294GO:0035249
GeneOntologyBiologicalProcesscerebellar cortex morphogenesis

PSAP DLL1 NRXN1

4.14e-0548293GO:0021696
GeneOntologyBiologicalProcessepidermal cell differentiation

KCNMA1 JAG2 PSAP DLL1 JAG1

4.33e-05284295GO:0009913
GeneOntologyBiologicalProcessear development

KCNMA1 JAG2 PSAP DLL1 JAG1

4.40e-05285295GO:0043583
GeneOntologyBiologicalProcesscell fate determination

JAG2 DLL1 JAG1

4.68e-0550293GO:0001709
GeneOntologyBiologicalProcessadult walking behavior

KCNMA1 SCN1A SCN8A

4.68e-0550293GO:0007628
GeneOntologyBiologicalProcesspositive regulation of Notch signaling pathway

JAG2 DLL1 JAG1

5.58e-0553293GO:0045747
GeneOntologyBiologicalProcesscerebellum morphogenesis

PSAP DLL1 NRXN1

8.10e-0560293GO:0021587
GeneOntologyBiologicalProcessloop of Henle development

DLL1 JAG1

8.53e-0510292GO:0072070
GeneOntologyBiologicalProcessheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

SCARF1 NRXN1 TENM3

9.38e-0563293GO:0007157
GeneOntologyBiologicalProcessneuronal action potential

KCNMA1 SCN1A SCN8A

9.38e-0563293GO:0019228
GeneOntologyBiologicalProcesshindbrain morphogenesis

PSAP DLL1 NRXN1

9.83e-0564293GO:0021575
GeneOntologyBiologicalProcessmicturition

KCNMA1 PSAP

1.04e-0411292GO:0060073
GeneOntologyBiologicalProcessregulation of membrane potential

KCNMA1 LTF GRM1 NRXN1 SCN1A SCN8A

1.08e-04559296GO:0042391
GeneOntologyBiologicalProcessanatomical structure maturation

SCARF1 KCNMA1 LTF FGG NRXN1

1.22e-04354295GO:0071695
GeneOntologyBiologicalProcesscerebellar cortex development

PSAP DLL1 NRXN1

1.34e-0471293GO:0021695
GeneOntologyBiologicalProcessnegative regulation of multicellular organismal process

KCNMA1 CYLD FXR1 LTF FGG DLL1 ADCY7 SLIT1 ADGRB1

1.38e-041488299GO:0051241
GeneOntologyBiologicalProcessneuromuscular process controlling balance

KCNMA1 PSAP NRXN1

1.51e-0474293GO:0050885
GeneOntologyBiologicalProcessneuron maturation

SCARF1 KCNMA1 NRXN1

1.51e-0474293GO:0042551
GeneOntologyBiologicalProcessadult behavior

KCNMA1 NRXN1 SCN1A SCN8A

1.78e-04203294GO:0030534
GeneOntologyBiologicalProcessregulation of nervous system development

LRP2 FXR1 DLL1 NRXN1 SLIT1 ADGRB1

1.98e-04625296GO:0051960
GeneOntologyBiologicalProcessregulation of timing of cell differentiation

DLL1 JAG1

1.98e-0415292GO:0048505
GeneOntologyBiologicalProcessaxon development

SCARF1 LRP2 ALS2 NRXN1 SLIT1 ADGRB1

2.29e-04642296GO:0061564
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

PSAP GRM1 ADCY7

2.36e-0486293GO:0007193
GeneOntologyBiologicalProcessregulation of development, heterochronic

DLL1 JAG1

2.56e-0417292GO:0040034
GeneOntologyBiologicalProcessneuromuscular process

KCNMA1 PSAP NRXN1 SCN1A

2.64e-04225294GO:0050905
GeneOntologyBiologicalProcessregulation of synaptic transmission, glutamatergic

FXR1 GRM1 NRXN1

2.88e-0492293GO:0051966
GeneOntologyBiologicalProcessmuscle organ development

LRP2 FXR1 DLL1 SCN8A ADGRB1

3.22e-04436295GO:0007517
GeneOntologyBiologicalProcessdevelopmental maturation

SCARF1 KCNMA1 LTF FGG NRXN1

3.32e-04439295GO:0021700
GeneOntologyBiologicalProcessregulation of response to external stimulus

SCARF1 CYLD FXR1 LTF FGG NRXN1 CXCL17 SLIT1

3.45e-041316298GO:0032101
GeneOntologyBiologicalProcessnegative regulation of cytokine production

CYLD FXR1 LTF DLL1 ADCY7

3.50e-04444295GO:0001818
GeneOntologyBiologicalProcessregulation of cytokine production

CYLD OAS2 FXR1 LTF DLL1 CXCL17 ADCY7

4.00e-041010297GO:0001817
GeneOntologyBiologicalProcessepidermis development

KCNMA1 JAG2 PSAP DLL1 JAG1

4.16e-04461295GO:0008544
GeneOntologyBiologicalProcesssensory organ development

KCNMA1 JAG2 PSAP DLL1 TENM3 JAG1

4.55e-04730296GO:0007423
GeneOntologyBiologicalProcesscirculatory system process

KCNMA1 LRP2 FGG DLL1 SCN1A SCN8A

4.65e-04733296GO:0003013
GeneOntologyBiologicalProcesscell maturation

SCARF1 KCNMA1 FGG NRXN1

5.05e-04267294GO:0048469
GeneOntologyBiologicalProcesstransmission of nerve impulse

KCNMA1 SCN1A SCN8A

5.14e-04112293GO:0019226
GeneOntologyBiologicalProcesslysosomal protein catabolic process

LRP2 PSAP

5.17e-0424292GO:1905146
GeneOntologyBiologicalProcessepithelial cell development

KCNMA1 PSAP DLL1 JAG1

5.20e-04269294GO:0002064
GeneOntologyBiologicalProcessregulation of Notch signaling pathway

JAG2 DLL1 JAG1

5.41e-04114293GO:0008593
GeneOntologyBiologicalProcesscerebellar Purkinje cell layer morphogenesis

PSAP DLL1

5.61e-0425292GO:0021692
GeneOntologyBiologicalProcessadult locomotory behavior

KCNMA1 SCN1A SCN8A

5.69e-04116293GO:0008344
GeneOntologyBiologicalProcesssensory perception

KCNMA1 JAG2 LRP2 PSAP GRM1 SCN1A SCN8A

5.72e-041072297GO:0007600
GeneOntologyBiologicalProcesscytokine production

CYLD OAS2 FXR1 LTF DLL1 CXCL17 ADCY7

6.35e-041091297GO:0001816
GeneOntologyBiologicalProcessregulation of cell development

LRP2 CYLD FXR1 LTF DLL1 JAG1 SLIT1

6.49e-041095297GO:0060284
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

PSAP GRM1 ADCY7 ADGRB1

6.54e-04286294GO:0007188
GeneOntologyBiologicalProcessneuron development

SCARF1 KCNMA1 LRP2 ALS2 NRXN1 TENM3 SLIT1 ADGRB1

7.01e-041463298GO:0048666
GeneOntologyBiologicalProcessprotein catabolic process in the vacuole

LRP2 PSAP

7.05e-0428292GO:0007039
GeneOntologyBiologicalProcessregulation of MAPK cascade

CYLD FGG PSAP GRM1 NRXN1 CXCL17

8.14e-04815296GO:0043408
GeneOntologyBiologicalProcessblood vessel morphogenesis

LRP2 DLL1 NRXN1 CXCL17 JAG1 ADGRB1

8.24e-04817296GO:0048514
GeneOntologyBiologicalProcesscell differentiation in hindbrain

PSAP NRXN1

9.22e-0432292GO:0021533
GeneOntologyBiologicalProcesscerebellum development

PSAP DLL1 NRXN1

9.63e-04139293GO:0021549
GeneOntologyBiologicalProcessaxonogenesis

LRP2 ALS2 NRXN1 SLIT1 ADGRB1

1.05e-03566295GO:0007409
GeneOntologyBiologicalProcessmuscle structure development

LRP2 FXR1 DLL1 JAG1 SCN8A ADGRB1

1.06e-03858296GO:0061061
GeneOntologyBiologicalProcessbrain development

LRP2 FXR1 PSAP DLL1 NRXN1 SLIT1

1.07e-03859296GO:0007420
GeneOntologyBiologicalProcesspositive regulation of MAPK cascade

FGG PSAP GRM1 NRXN1 CXCL17

1.09e-03571295GO:0043410
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN1A SCN8A

1.17e-0336292GO:0086010
GeneOntologyBiologicalProcesscell fate commitment

JAG2 CYLD DLL1 JAG1

1.22e-03338294GO:0045165
GeneOntologyBiologicalProcessexcretion

KCNMA1 PSAP

1.23e-0337292GO:0007588
GeneOntologyBiologicalProcessmetencephalon development

PSAP DLL1 NRXN1

1.27e-03153293GO:0022037
GeneOntologyBiologicalProcesspositive regulation of protein localization

LRP2 CYLD SEC16B FGG NRXN1

1.28e-03591295GO:1903829
GeneOntologyBiologicalProcesscerebellar Purkinje cell layer development

PSAP DLL1

1.37e-0339292GO:0021680
GeneOntologyBiologicalProcessresponse to calcium ion

KCNMA1 FGG NRXN1

1.47e-03161293GO:0051592
GeneOntologyBiologicalProcesshead development

LRP2 FXR1 PSAP DLL1 NRXN1 SLIT1

1.52e-03919296GO:0060322
GeneOntologyBiologicalProcessanimal organ morphogenesis

JAG2 LRP2 LTF DLL1 TENM3 JAG1 SLIT1

1.55e-031269297GO:0009887
GeneOntologyBiologicalProcesscolumnar/cuboidal epithelial cell differentiation

KCNMA1 DLL1 JAG1

1.55e-03164293GO:0002065
GeneOntologyBiologicalProcessregulation of cell adhesion

JAG2 CYLD FGG DLL1 TENM3 JAG1

1.58e-03927296GO:0030155
GeneOntologyBiologicalProcesssynaptic membrane adhesion

NRXN1 TENM3

1.59e-0342292GO:0099560
GeneOntologyBiologicalProcessblood vessel development

LRP2 DLL1 NRXN1 CXCL17 JAG1 ADGRB1

1.60e-03929296GO:0001568
GeneOntologyBiologicalProcessMAPK cascade

CYLD FGG PSAP GRM1 NRXN1 CXCL17

1.61e-03930296GO:0000165
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

KCNMA1 ALS2 FXR1 GRM1 NRXN1 ADGRB1

1.62e-03931296GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

KCNMA1 ALS2 FXR1 GRM1 NRXN1 ADGRB1

1.62e-03931296GO:0007268
GeneOntologyCellularComponentpresynaptic membrane

KCNMA1 GRM1 NRXN1 TENM3 SCN1A SCN8A

2.33e-06277306GO:0042734
GeneOntologyCellularComponentaxon

KCNMA1 LRP2 ALS2 FXR1 GRM1 NRXN1 TENM3 SCN1A SCN8A

2.84e-06891309GO:0030424
GeneOntologyCellularComponentpresynaptic active zone membrane

KCNMA1 NRXN1 TENM3 SCN8A

4.57e-0678304GO:0048787
GeneOntologyCellularComponentglutamatergic synapse

KCNMA1 ALS2 FXR1 GRM1 NRXN1 TENM3 SCN8A ADGRB1

1.43e-05817308GO:0098978
GeneOntologyCellularComponentsynaptic membrane

KCNMA1 GRM1 NRXN1 TENM3 SCN1A SCN8A ADGRB1

1.47e-05583307GO:0097060
GeneOntologyCellularComponentsomatodendritic compartment

KCNMA1 LRP2 ALS2 FXR1 GRM1 NRXN1 SCN1A SCN8A ADGRB1

3.76e-051228309GO:0036477
GeneOntologyCellularComponentpresynaptic active zone

KCNMA1 NRXN1 TENM3 SCN8A

4.74e-05141304GO:0048786
GeneOntologyCellularComponentdendrite

KCNMA1 LRP2 ALS2 FXR1 GRM1 SCN8A ADGRB1

1.70e-04858307GO:0030425
GeneOntologyCellularComponentdendritic tree

KCNMA1 LRP2 ALS2 FXR1 GRM1 SCN8A ADGRB1

1.73e-04860307GO:0097447
GeneOntologyCellularComponentpresynapse

KCNMA1 FXR1 GRM1 NRXN1 TENM3 SCN1A SCN8A

2.08e-04886307GO:0098793
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN8A

2.67e-0417302GO:0001518
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN8A

3.72e-0420302GO:0033268
GeneOntologyCellularComponentdendritic spine

ALS2 FXR1 GRM1 ADGRB1

3.79e-04242304GO:0043197
GeneOntologyCellularComponentneuron spine

ALS2 FXR1 GRM1 ADGRB1

4.09e-04247304GO:0044309
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN8A

7.89e-0429302GO:0043194
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN8A

7.89e-0429302GO:0034706
GeneOntologyCellularComponentneuron to neuron synapse

ALS2 GRM1 NRXN1 SCN8A ADGRB1

8.17e-04523305GO:0098984
GeneOntologyCellularComponentneuronal cell body

KCNMA1 ALS2 GRM1 NRXN1 SCN1A SCN8A

1.04e-03835306GO:0043025
GeneOntologyCellularComponentcell-cell junction

DLL1 NRXN1 SCN1A JAG1 ADGRB1

1.41e-03591305GO:0005911
GeneOntologyCellularComponentcell body

KCNMA1 ALS2 GRM1 NRXN1 SCN1A SCN8A

1.80e-03929306GO:0044297
GeneOntologyCellularComponentperinuclear region of cytoplasm

KCNMA1 JAG2 CYLD OAS2 FXR1 ADGRB1

1.85e-03934306GO:0048471
GeneOntologyCellularComponentaxonal growth cone

LRP2 NRXN1

1.90e-0345302GO:0044295
GeneOntologyCellularComponentendocytic vesicle

SCARF1 LRP2 LTF NRXN1

2.11e-03384304GO:0030139
GeneOntologyCellularComponentpostsynaptic membrane

KCNMA1 GRM1 SCN8A ADGRB1

2.55e-03405304GO:0045211
GeneOntologyCellularComponentpostsynapse

KCNMA1 ALS2 FXR1 GRM1 SCN8A ADGRB1

2.85e-031018306GO:0098794
GeneOntologyCellularComponentdistal axon

KCNMA1 LRP2 ALS2 NRXN1

3.30e-03435304GO:0150034
GeneOntologyCellularComponentpostsynaptic density

ALS2 GRM1 SCN8A ADGRB1

3.76e-03451304GO:0014069
GeneOntologyCellularComponentcell surface

KCNMA1 LRP2 LTF FGG LY75 NRXN1

4.40e-031111306GO:0009986
GeneOntologyCellularComponentcation channel complex

KCNMA1 SCN1A SCN8A

4.55e-03235303GO:0034703
GeneOntologyCellularComponentasymmetric synapse

ALS2 GRM1 SCN8A ADGRB1

4.58e-03477304GO:0032279
GeneOntologyCellularComponentapical plasma membrane

KCNMA1 LRP2 DLL1 JAG1

4.93e-03487304GO:0016324
GeneOntologyCellularComponentgrowth cone

LRP2 ALS2 NRXN1

5.11e-03245303GO:0030426
GeneOntologyCellularComponentpostsynaptic specialization

ALS2 GRM1 SCN8A ADGRB1

5.53e-03503304GO:0099572
GeneOntologyCellularComponentsite of polarized growth

LRP2 ALS2 NRXN1

5.59e-03253303GO:0030427
GeneOntologyCellularComponentexternal side of plasma membrane

KCNMA1 LRP2 FGG LY75

6.17e-03519304GO:0009897
GeneOntologyCellularComponentmyofibril

FXR1 SCN1A SCN8A

6.89e-03273303GO:0030016
GeneOntologyCellularComponentmain axon

SCN1A SCN8A

7.22e-0389302GO:0044304
GeneOntologyCellularComponentside of membrane

KCNMA1 LRP2 CYLD FGG LY75

7.58e-03875305GO:0098552
GeneOntologyCellularComponentcontractile muscle fiber

FXR1 SCN1A SCN8A

8.13e-03290303GO:0043292
GeneOntologyCellularComponentapical part of cell

KCNMA1 LRP2 DLL1 JAG1

9.73e-03592304GO:0045177
GeneOntologyCellularComponentexcitatory synapse

NRXN1 SCN8A

1.03e-02107302GO:0060076
GeneOntologyCellularComponentanchoring junction

DLL1 NRXN1 SCN1A JAG1 ADGRB1

1.18e-02976305GO:0070161
HumanPhenoBilateral tonic-clonic seizure with focal onset

KCNMA1 PSAP SCN1A SCN8A

1.21e-0552154HP:0007334
HumanPhenoEEG with spike-wave complexes (>3.5 Hz)

KCNMA1 SCN1A

4.84e-054152HP:0010849
MousePhenoabnormal ventral spinal root morphology

ALS2 PSAP SCN8A

6.83e-0619283MP:0003993
MousePhenopremature death

KCNMA1 CYLD FXR1 PSAP GRM1 DLL1 TENM3 SCN1A JAG1 SCN8A

2.07e-0510512810MP:0002083
MousePhenoabnormal head movements

PSAP SCN1A JAG1 SCN8A

4.97e-05103284MP:0000436
MousePhenoabnormal spinal nerve morphology

ALS2 PSAP DLL1 SCN8A

5.77e-05107284MP:0001077
MousePhenotremors

KCNMA1 PSAP GRM1 NRXN1 SCN1A SCN8A

5.85e-05353286MP:0000745
MousePhenostereotypic behavior

KCNMA1 PSAP SCN1A JAG1 SCN8A

5.92e-05214285MP:0001408
MousePhenoabnormal organ of Corti supporting cell morphology

KCNMA1 JAG2 PSAP

9.02e-0544283MP:0004300
MousePhenoabnormal cochlear labyrinth morphology

KCNMA1 JAG2 LRP2 PSAP JAG1

9.22e-05235285MP:0004426
MousePhenoabnormal scala media morphology

KCNMA1 JAG2 LRP2 PSAP JAG1

9.22e-05235285MP:0003169
MousePhenoimpaired balance

PSAP GRM1 JAG1 SCN8A

9.31e-05121284MP:0001525
MousePhenoabnormal cochlear inner hair cell morphology

KCNMA1 JAG2 PSAP JAG1

1.02e-04124284MP:0004393
MousePhenoabnormal cochlea morphology

KCNMA1 JAG2 LRP2 PSAP JAG1

1.19e-04248285MP:0000031
MousePhenoabnormal action potential

KCNMA1 ALS2 SCN1A SCN8A

1.34e-04133284MP:0005402
MousePhenoabnormal skin vasculature morphology

FXR1 DLL1

1.38e-049282MP:0014273
MousePhenoabnormal membranous labyrinth morphology

KCNMA1 JAG2 LRP2 PSAP JAG1

1.54e-04262285MP:0000035
MousePhenoataxia

KCNMA1 PSAP GRM1 SCN1A SCN8A

1.65e-04266285MP:0001393
MousePhenodecreased cerebellar granule cell number

PSAP SCN8A

1.72e-0410282MP:0008924
MousePhenoabnormal stationary movement

PSAP SCN1A JAG1 SCN8A

1.97e-04147284MP:0001388
MousePhenoabnormal cochlear IHC afferent innervation pattern

KCNMA1 PSAP

2.10e-0411282MP:0004746
MousePhenoabnormal Deiters cell morphology

KCNMA1 PSAP

2.10e-0411282MP:0004302
MousePhenoimpaired limb coordination

PSAP GRM1 SCN8A

2.17e-0459283MP:0001524
MousePhenoabnormal motor coordination/balance

KCNMA1 LRP2 ALS2 PSAP GRM1 SCN1A JAG1 SCN8A

2.27e-04873288MP:0001516
MousePhenoabnormal enzyme/coenzyme activity

LRP2 CYLD PSAP DSEL DLL1

2.35e-04287285MP:0005584
MousePhenoabnormal neuron number

JAG2 ALS2 PSAP DLL1 JAG1 SCN8A

2.38e-04456286MP:0008946
MousePhenoabnormal cochlear outer hair cell morphology

KCNMA1 JAG2 PSAP JAG1

2.67e-04159284MP:0004399
MousePhenoimpaired ability to fire action potentials

KCNMA1 SCN1A

2.98e-0413282MP:0002578
MousePhenoabnormal inner ear morphology

KCNMA1 JAG2 LRP2 PSAP JAG1

3.02e-04303285MP:0000026
MousePhenoimpaired coordination

KCNMA1 LRP2 ALS2 PSAP GRM1 SCN8A

3.07e-04478286MP:0001405
MousePhenodecreased Purkinje cell number

ALS2 PSAP SCN8A

3.16e-0467283MP:0000880
MousePhenoshort stride length

KCNMA1 FXR1 PSAP

3.45e-0469283MP:0001407
MousePhenoabnormal Purkinje cell number

ALS2 PSAP SCN8A

3.45e-0469283MP:0000878
MousePhenoincreased cochlear inner hair cell number

JAG2 JAG1

3.47e-0414282MP:0004395
MousePhenoincreased neuron number

JAG2 DLL1 JAG1

3.91e-0472283MP:0008947
MousePhenoabnormal nervous system electrophysiology

KCNMA1 ALS2 GRM1 SCN1A SCN8A

4.41e-04329285MP:0002272
MousePhenoabnormal gait

KCNMA1 FXR1 PSAP GRM1 SCN1A SCN8A

4.82e-04520286MP:0001406
MousePhenoabnormal innervation

KCNMA1 ALS2 PSAP TENM3

5.56e-04193284MP:0002184
MousePhenoabnormal stride length

KCNMA1 FXR1 PSAP

5.73e-0482283MP:0012690
MousePhenoabnormal cochlear hair cell morphology

KCNMA1 JAG2 PSAP JAG1

6.60e-04202284MP:0002622
MousePhenoabnormal somatic nervous system morphology

KCNMA1 JAG2 ALS2 PSAP DLL1 TENM3 JAG1 SCN8A

6.72e-041025288MP:0002752
MousePhenoabnormal hippocampus granule cell layer

PSAP SCN1A

7.19e-0420282MP:0008285
MousePhenoincreased cochlear hair cell number

JAG2 JAG1

7.19e-0420282MP:0004407
MousePhenoabnormal cochlear sensory epithelium morphology

KCNMA1 JAG2 PSAP JAG1

7.24e-04207284MP:0003308
MousePhenoabnormal organ of Corti morphology

KCNMA1 JAG2 PSAP JAG1

7.50e-04209284MP:0000042
MousePhenoaxon degeneration

ALS2 PSAP SCN8A

7.77e-0491283MP:0005405
MousePhenohunched posture

CYLD GRM1 SCN8A

7.77e-0491283MP:0001505
MousePhenoabnormal sensory neuron innervation pattern

KCNMA1 PSAP TENM3

8.02e-0492283MP:0000968
MousePhenoabnormal hippocampus layer morphology

PSAP SCN1A ADGRB1

8.02e-0492283MP:0000813
MousePhenoabnormal hair cell morphology

KCNMA1 JAG2 PSAP JAG1

8.19e-04214284MP:0000045
MousePhenoabnormal cochlear sensory neuron innervation pattern

KCNMA1 PSAP

8.72e-0422282MP:0014489
MousePhenohead shaking

PSAP JAG1

8.72e-0422282MP:0002730
MousePhenomuscular atrophy

ALS2 PSAP SCN8A

9.08e-0496283MP:0002269
MousePhenoimpaired hearing

KCNMA1 LRP2 PSAP SCN8A

9.55e-04223284MP:0006325
MousePhenodecreased locomotor activity

ALS2 PSAP GRM1 DLL1 TXNDC11 SLIT1 SCN8A

9.93e-04829287MP:0001402
MousePhenoabnormal respiration

JAG2 LRP2 CYLD NRXN1 SCN1A SCN8A

1.01e-03598286MP:0001943
MousePhenoabnormal spike wave discharge

SCN1A SCN8A

1.04e-0324282MP:0008840
MousePhenoabnormal habituation

PSAP SCN1A

1.04e-0324282MP:0011617
MousePhenoabnormal respiratory function

JAG2 CYLD NRXN1 SCN1A SCN8A

1.06e-03399285MP:0002327
MousePhenoabnormal mechanoreceptor morphology

KCNMA1 JAG2 PSAP JAG1

1.09e-03231284MP:0000972
MousePhenotonic seizures

PSAP SCN1A

1.13e-0325282MP:0002826
MousePhenoabnormal synaptic depression

KCNMA1 GRM1 ADGRB1

1.24e-03107283MP:0002915
MousePhenoabnormal posture

CYLD GRM1 SCN1A SCN8A

1.31e-03243284MP:0001504
MousePhenoabnormal nonassociative learning

PSAP SCN1A

1.32e-0327282MP:0011616
MousePhenoabnormal nephron morphology

SCARF1 KCNMA1 LRP2 PSAP GRM1

1.41e-03426285MP:0003881
MousePhenokinked tail

JAG2 LRP2 CYLD

1.49e-03114283MP:0000585
MousePhenoabnormal respiratory system physiology

JAG2 LRP2 CYLD PSAP NRXN1 SCN1A SCN8A

1.57e-03897287MP:0002133
MousePhenocircling

KCNMA1 SCN1A JAG1

1.61e-03117283MP:0001394
MousePhenoabnormal cochlear inner hair cell number

JAG2 JAG1

1.63e-0330282MP:0004394
MousePhenoparaparesis

PSAP SCN8A

1.85e-0332282MP:0009434
MousePhenoprogressive muscle weakness

PSAP SCN8A

2.09e-0334282MP:0000748
MousePhenoabnormal ear morphology

KCNMA1 JAG2 LRP2 PSAP JAG1

2.18e-03470285MP:0002102
MousePhenohead tossing

JAG1 SCN8A

2.21e-0335282MP:0005307
MousePhenoabsence seizures

SCN1A SCN8A

2.21e-0335282MP:0003216
MousePhenoabnormal sensory neuron morphology

KCNMA1 JAG2 PSAP TENM3 JAG1

2.24e-03473285MP:0000965
MousePhenoabnormal somatic sensory system morphology

KCNMA1 JAG2 PSAP DLL1 TENM3 JAG1

2.29e-03702286MP:0000959
MousePhenohindlimb paresis

PSAP SCN8A

2.47e-0337282MP:0031204
MousePhenoabnormal urinary bladder physiology

KCNMA1 PSAP

2.47e-0337282MP:0010386
MousePhenosensorineural hearing loss

KCNMA1 PSAP

2.47e-0337282MP:0004740
MousePhenodecreased neuronal precursor cell number

DLL1 JAG1

2.47e-0337282MP:0004981
MousePhenoabnormal susceptibility to hearing loss

KCNMA1 LRP2

2.60e-0338282MP:0006334
MousePhenosensorineural hearing impairment

KCNMA1 PSAP

2.60e-0338282MP:0006329
MousePhenolethality during fetal growth through weaning, complete penetrance

JAG2 LRP2 CYLD FXR1 DLL1 ADCY7 SCN1A SCN8A

2.69e-031269288MP:0011111
MousePhenoabnormal locomotor coordination

KCNMA1 FXR1 PSAP GRM1 SCN1A SCN8A

2.71e-03726286MP:0003312
MousePhenoabnormal cerebellar cortex morphology

LRP2 ALS2 PSAP SCN8A

2.83e-03300284MP:0004097
MousePhenoabnormal cochlear hair cell physiology

KCNMA1 PSAP

2.88e-0340282MP:0004432
MousePhenononconvulsive seizures

SCN1A SCN8A

2.88e-0340282MP:0000948
MousePhenoabnormal breathing pattern

JAG2 NRXN1 SCN1A SCN8A

2.94e-03303284MP:0001951
MousePhenoincreased sensory neuron number

JAG2 JAG1

3.02e-0341282MP:0006006
MousePhenoincreased urine protein level

SCARF1 LRP2 GRM1

3.20e-03149283MP:0002962
MousePhenoincreased anxiety-related response

ALS2 SCN1A TXNDC11 SCN8A

3.23e-03311284MP:0001363
MousePhenoreduced long-term depression

GRM1 ADGRB1

3.32e-0343282MP:0001475
MousePhenohypoactivity

ALS2 PSAP GRM1 DLL1 TXNDC11 SLIT1 SCN8A

3.34e-031023287MP:0031392
MousePhenoconvulsive seizures

PSAP SCN1A SCN8A

3.45e-03153283MP:0000947
MousePhenoabnormal cerebellar granule cell morphology

PSAP SCN8A

3.63e-0345282MP:0004098
MousePhenoincreased skin tumor incidence

CYLD GRM1

3.63e-0345282MP:0010300
MousePhenoabnormal nest building behavior

NRXN1 SCN1A

3.63e-0345282MP:0001447
DomainEGF_3

SCARF1 JAG2 LRP2 DLL1 NRXN1 TENM3 JAG1 SLIT1

2.57e-09235308PS50026
DomainEGF

SCARF1 JAG2 LRP2 DLL1 NRXN1 TENM3 JAG1 SLIT1

2.57e-09235308SM00181
DomainEGF-like_dom

SCARF1 JAG2 LRP2 DLL1 NRXN1 TENM3 JAG1 SLIT1

4.05e-09249308IPR000742
DomainEGF_1

SCARF1 JAG2 LRP2 DLL1 NRXN1 TENM3 JAG1 SLIT1

4.88e-09255308PS00022
DomainEGF-like_CS

SCARF1 JAG2 LRP2 DLL1 NRXN1 TENM3 JAG1 SLIT1

5.86e-09261308IPR013032
DomainEGF_2

SCARF1 JAG2 LRP2 DLL1 NRXN1 TENM3 JAG1 SLIT1

6.60e-09265308PS01186
DomainDSL

JAG2 DLL1 JAG1

1.49e-084303PF01414
DomainDSL

JAG2 DLL1 JAG1

1.49e-084303SM00051
DomainEGF-type_Asp/Asn_hydroxyl_site

JAG2 LRP2 DLL1 NRXN1 JAG1 SLIT1

1.54e-08106306IPR000152
DomainDSL

JAG2 DLL1 JAG1

3.73e-085303IPR001774
DomainDSL

JAG2 DLL1 JAG1

3.73e-085303PS51051
DomainNotch_ligand_N

JAG2 DLL1 JAG1

3.73e-085303IPR011651
DomainMNNL

JAG2 DLL1 JAG1

3.73e-085303PF07657
DomainEGF_extracell

SCARF1 JAG2 LRP2 TENM3 JAG1

3.87e-0860305IPR013111
DomainEGF_2

SCARF1 JAG2 LRP2 TENM3 JAG1

3.87e-0860305PF07974
DomainEGF

JAG2 LRP2 DLL1 NRXN1 JAG1 SLIT1

4.35e-08126306PF00008
DomainhEGF

JAG2 DLL1 JAG1 SLIT1

1.08e-0728304PF12661
DomainGrowth_fac_rcpt_

SCARF1 JAG2 LRP2 DLL1 JAG1 SLIT1

1.55e-07156306IPR009030
DomainEGF_Ca-bd_CS

JAG2 LRP2 DLL1 JAG1 SLIT1

4.38e-0797305IPR018097
DomainEGF_CA

JAG2 LRP2 DLL1 JAG1 SLIT1

4.85e-0799305PS01187
DomainASX_HYDROXYL

JAG2 LRP2 DLL1 NRXN1 JAG1

5.10e-07100305PS00010
DomainEGF_CA

JAG2 LRP2 DLL1 JAG1 SLIT1

1.37e-06122305SM00179
DomainEGF-like_Ca-bd_dom

JAG2 LRP2 DLL1 JAG1 SLIT1

1.48e-06124305IPR001881
DomainJagged/Serrate

JAG2 JAG1

2.49e-062302IPR026219
DomainNa_trans_cytopl

SCN1A SCN8A

3.73e-056302PF11933
DomainNa_trans_cytopl

SCN1A SCN8A

3.73e-056302IPR024583
DomainNa_channel_asu

SCN1A SCN8A

1.11e-0410302IPR001696
DomainNa_trans_assoc

SCN1A SCN8A

1.11e-0410302IPR010526
DomainNa_trans_assoc

SCN1A SCN8A

1.11e-0410302PF06512
DomainEGF_CA

JAG2 LRP2 JAG1

3.50e-0486303PF07645
DomainVWC_out

JAG2 JAG1

4.19e-0419302SM00215
DomainIon_trans_dom

KCNMA1 SCN1A SCN8A

7.97e-04114303IPR005821
DomainIon_trans

KCNMA1 SCN1A SCN8A

7.97e-04114303PF00520
DomainLAM_G_DOMAIN

NRXN1 SLIT1

1.69e-0338302PS50025
DomainVWC

JAG2 JAG1

1.69e-0338302SM00214
Domain-

LRP2 TENM3

1.78e-03393022.120.10.30
DomainLaminin_G_2

NRXN1 SLIT1

1.87e-0340302PF02210
DomainVWF_dom

JAG2 JAG1

2.06e-0342302IPR001007
DomainLamG

NRXN1 SLIT1

2.26e-0344302SM00282
Domain6-blade_b-propeller_TolB-like

LRP2 TENM3

2.47e-0346302IPR011042
DomainChannel_four-helix_dom

SCN1A SCN8A

3.77e-0357302IPR027359
Domain-

SCN1A SCN8A

3.77e-03573021.20.120.350
DomainLaminin_G

NRXN1 SLIT1

3.90e-0358302IPR001791
PathwayREACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT

JAG2 DLL1 JAG1

2.18e-077273M27199
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION

JAG2 DLL1 JAG1

5.22e-079273M47866
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

JAG2 DLL1 JAG1

1.77e-0613273M47423
PathwayREACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER

JAG2 DLL1 JAG1

2.81e-0615273M27202
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

JAG2 DLL1 JAG1

3.45e-0616273M47424
PathwayWP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION

JAG2 DLL1 JAG1

4.19e-0617273M39389
PathwayREACTOME_SIGNALING_BY_NOTCH3

JAG2 DLL1 JAG1

5.95e-0619273MM15594
PathwayREACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

JAG2 DLL1 JAG1

9.42e-0622273M27210
PathwayREACTOME_NOTCH3_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

JAG2 DLL1 JAG1

1.40e-0525273M27879
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

JAG2 DLL1 JAG1

1.78e-0527273M39545
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

JAG2 DLL1 JAG1

2.72e-0531273M592
PathwayREACTOME_SIGNALING_BY_NOTCH2

JAG2 DLL1 JAG1

3.29e-0533273M604
PathwayREACTOME_SIGNALING_BY_NOTCH

JAG2 DLL1 JAG1

5.47e-0539273MM14604
PathwayWP_NOTCH_SIGNALING_WP268

JAG2 DLL1 JAG1

8.43e-0545273M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

JAG2 DLL1 JAG1

9.00e-0546273MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

JAG2 DLL1 JAG1

9.61e-0547273M7946
PathwayREACTOME_SIGNALING_BY_NOTCH3

JAG2 DLL1 JAG1

1.09e-0449273M618
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

JAG2 DLL1 JAG1

1.80e-0458273M29616
PathwayPID_NOTCH_PATHWAY

JAG2 DLL1 JAG1

1.90e-0459273M17
PathwayWP_NOTCH_SIGNALING_WP61

JAG2 DLL1 JAG1

2.09e-0461273M39540
PathwayREACTOME_NEPHRON_DEVELOPMENT

DLL1 JAG1

2.72e-0413272M48245
PathwayREACTOME_SIGNALING_BY_NOTCH1

JAG2 DLL1 JAG1

3.71e-0474273M616
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

JAG2 DLL1 JAG1

5.02e-0482273MM15922
PathwayWP_DRAVET_SYNDROME

SCN1A SCN8A

1.29e-0328272M45519
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

JAG2 DLL1 JAG1

1.44e-03118273M39852
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN1A SCN8A

1.59e-0331272M877
PathwayREACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

JAG2 FXR1 FGG DLL1 JAG1

1.68e-03464275M27547
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN1A SCN8A

1.69e-0332272M27455
PathwayREACTOME_NEUREXINS_AND_NEUROLIGINS

GRM1 NRXN1

1.69e-0332272MM15326
PathwayWP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV

GRM1 NRXN1

1.80e-0333272M39875
Pubmed

Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels.

JAG2 GRM1 DLL1 JAG1 SLIT1

5.17e-122030529961574
Pubmed

Stromal expression of Jagged 1 promotes colony formation by fetal hematopoietic progenitor cells.

JAG2 DLL1 JAG1

5.79e-1033039716576
Pubmed

Notch ligands transduce different magnitudes of signaling critical for determination of T-cell fate.

JAG2 DLL1 JAG1

2.32e-09430320602435
Pubmed

Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor.

JAG2 DLL1 JAG1

2.32e-0943039315665
Pubmed

The Notch signalling pathway in hair growth.

JAG2 DLL1 JAG1

2.32e-0943039858728
Pubmed

Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors.

JAG2 DLL1 JAG1

5.78e-09530311006133
Pubmed

Notch-3 and Notch-4 signaling rescue from apoptosis human B-ALL cells in contact with human bone marrow-derived mesenchymal stromal cells.

JAG2 DLL1 JAG1

5.78e-09530321602525
Pubmed

The extracellular matrix protein MAGP-2 interacts with Jagged1 and induces its shedding from the cell surface.

JAG2 DLL1 JAG1

5.78e-09530315788413
Pubmed

Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain.

JAG2 DLL1 JAG1

5.78e-09530312175503
Pubmed

Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2.

JAG2 DLL1 JAG1

1.16e-08630310958687
Pubmed

Human ligands of the Notch receptor.

JAG2 DLL1 JAG1

2.02e-08730310079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

JAG2 DLL1 JAG1

2.02e-08730312846471
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

JAG2 DLL1 JAG1

3.23e-0883039858718
Pubmed

Notch/Delta expression in the developing mouse lung.

JAG2 DLL1 JAG1

3.23e-08830311044610
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

JAG2 DLL1 JAG1

4.85e-08930311118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

JAG2 DLL1 JAG1

4.85e-08930316245338
Pubmed

Notch signaling is essential for vascular morphogenesis in mice.

JAG2 DLL1 JAG1

4.85e-08930310837027
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

JAG2 DLL1 JAG1

6.92e-081030323665443
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

JAG2 DLL1 JAG1

9.51e-081130310878608
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

JAG2 DLL1 JAG1

9.51e-081130312866128
Pubmed

Dll3 is expressed in developing hair cells in the mammalian cochlea.

JAG2 DLL1 JAG1

1.27e-071230317823936
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

JAG2 DLL1 JAG1

1.27e-071230315465494
Pubmed

Jagged1 is Essential for Radial Glial Maintenance in the Cortical Proliferative Zone.

JAG2 DLL1 JAG1

1.65e-071330331202705
Pubmed

Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation.

JAG2 DLL1 JAG1

1.65e-071330311171333
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

JAG2 DLL1 JAG1

1.65e-071330311578869
Pubmed

Mash1 and Ngn1 control distinct steps of determination and differentiation in the olfactory sensory neuron lineage.

JAG2 DLL1 JAG1

1.65e-071330311934853
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

JAG2 DLL1 JAG1

2.09e-071430314757642
Pubmed

Notch1 is required for neuronal and glial differentiation in the cerebellum.

JAG2 DLL1 JAG1

2.09e-071430311807030
Pubmed

BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling.

JAG2 DLL1 JAG1

2.62e-071530316324690
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

JAG2 DLL1 JAG1

2.62e-071530312971992
Pubmed

Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth.

JAG2 DLL1 JAG1

2.62e-071530312167404
Pubmed

COUP-TFI controls Notch regulation of hair cell and support cell differentiation.

JAG2 DLL1 JAG1

2.62e-071530316914494
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

JAG2 DLL1 JAG1

3.22e-071630312617809
Pubmed

Notch gene expression during pancreatic organogenesis.

JAG2 DLL1 JAG1

3.22e-071630310842072
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

JAG2 DLL1 JAG1

3.22e-071630317273555
Pubmed

Synergistic, context-dependent, and hierarchical functions of epithelial components in thymic microenvironments.

JAG2 DLL1 JAG1

3.22e-071630322464328
Pubmed

Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice.

JAG2 DLL1 JAG1

3.22e-071630332161758
Pubmed

The role of Pax2 in mouse inner ear development.

JAG2 DLL1 JAG1

3.91e-071730315242798
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

JAG2 DLL1 JAG1

3.91e-071730318694942
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

JAG2 DLL1 JAG1

3.91e-071730315821257
Pubmed

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.

JAG2 DLL1 JAG1

4.68e-071830318093989
Pubmed

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

JAG2 DLL1 JAG1

4.68e-071830315689374
Pubmed

Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches.

JAG2 DLL1 JAG1

5.56e-071930318505817
Pubmed

Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.

JAG2 DLL1 JAG1

5.56e-071930316518823
Pubmed

Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves.

DLL1 JAG1 SLIT1

5.56e-071930325691540
Pubmed

Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas.

JAG2 DLL1 JAG1

6.54e-072030319501159
Pubmed

Cellular analysis of growth suppression induced by the Notch ligands, Delta-1 and Jagged-1 in two myeloid leukemia cell lines.

DLL1 JAG1

7.19e-07230215254769
Pubmed

In vitro effects of stromal cells expressing different levels of Jagged-1 and Delta-1 on the growth of primitive and intermediate CD34(+) cell subsets from human cord blood.

DLL1 JAG1

7.19e-07230221911304
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

7.19e-07230237901435
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

7.19e-07230226410685
Pubmed

NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma.

JAG2 JAG1

7.19e-07230224708907
Pubmed

Specific Jagged-1 signal from bone marrow microenvironment is required for endothelial progenitor cell development for neovascularization.

DLL1 JAG1

7.19e-07230218591437
Pubmed

The non-transmembrane form of Delta1, but not of Jagged1, induces normal migratory behavior accompanied by fibroblast growth factor receptor 1-dependent transformation.

DLL1 JAG1

7.19e-07230214769803
Pubmed

Jag1/2 maintain esophageal homeostasis and suppress foregut tumorigenesis by restricting the basal progenitor cell pool.

JAG2 JAG1

7.19e-07230238750026
Pubmed

[Murine and human hematopoietic progenitor cultures grown on stromal layers expressing Notch ligands].

DLL1 JAG1

7.19e-07230228537242
Pubmed

Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors.

DLL1 JAG1

7.19e-07230215486060
Pubmed

Human umbilical cord epithelial cells express Notch ligands Delta1 and Jagged1.

DLL1 JAG1

7.19e-07230219150223
Pubmed

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.

SCN1A SCN8A

7.19e-07230233411788
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

7.19e-07230231943325
Pubmed

Notch signaling in T cells is essential for allergic airway inflammation, but expression of the Notch ligands Jagged 1 and Jagged 2 on dendritic cells is dispensable.

JAG2 JAG1

7.19e-07230228111308
Pubmed

Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear.

DLL1 JAG1

7.19e-07230210473135
Pubmed

Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fibroblasts with distinct phenotypes.

DLL1 JAG1

7.19e-07230218688026
Pubmed

Immunohistological localization of Notch receptors and their ligands Delta and Jagged in synovial tissues of rheumatoid arthritis.

DLL1 JAG1

7.19e-07230216307184
Pubmed

Determinant roles of dendritic cell-expressed Notch Delta-like and Jagged ligands on anti-tumor T cell immunity.

JAG2 DLL1

7.19e-07230230940183
Pubmed

Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction.

JAG2 JAG1

7.19e-07230211549580
Pubmed

The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments.

DLL1 JAG1

7.19e-07230212826675
Pubmed

Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.

SCN1A SCN8A

7.19e-07230237665666
Pubmed

The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.

SCN1A SCN8A

7.19e-07230217881658
Pubmed

Mesenchymal cells are required for functional development of thymic epithelial cells.

JAG2 DLL1 JAG1

7.62e-072130317625108
Pubmed

Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation.

JAG2 DLL1 JAG1

7.62e-072130331631837
Pubmed

The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain.

JAG2 DLL1 JAG1

7.62e-072130319686682
Pubmed

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

JAG2 DLL1 JAG1

7.62e-072130328656980
Pubmed

FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development.

JAG2 DLL1 JAG1

7.62e-072130314651921
Pubmed

Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme.

JAG2 DLL1 JAG1

8.82e-072230321750033
Pubmed

Notch signalling regulates epibranchial placode patterning and segregation.

JAG2 DLL1 JAG1

1.01e-062330331988190
Pubmed

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.

JAG2 DLL1 JAG1

1.01e-062330314701881
Pubmed

Acheate-scute like 1 (Ascl1) is required for normal delta-like (Dll) gene expression and notch signaling during retinal development.

JAG2 DLL1 JAG1

1.01e-062330319191219
Pubmed

Hepatocyte nuclear factor 1β controls nephron tubular development.

JAG2 DLL1 JAG1

1.01e-062330323362349
Pubmed

PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division.

JAG2 DLL1 JAG1

1.01e-062330331504280
Pubmed

Hemodynamic force is required for vascular smooth muscle cell recruitment to blood vessels during mouse embryonic development.

JAG2 DLL1 JAG1

1.16e-062430330796970
Pubmed

Notch signaling controls liver development by regulating biliary differentiation.

JAG2 DLL1 JAG1

1.49e-062630319369401
Pubmed

Gene expression is dynamically regulated in retinal progenitor cells prior to and during overt cellular differentiation.

JAG2 DLL1 JAG1

1.67e-062730324148613
Pubmed

EGFL7 is expressed in bone microenvironment and promotes angiogenesis via ERK, STAT3, and integrin signaling cascades.

JAG2 LTF DLL1

2.08e-062930324909139
Pubmed

Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms.

JAG2 LTF DLL1

2.08e-062930324971735
Pubmed

Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.

JAG2 DLL1 JAG1

2.08e-062930325535917
Pubmed

Notch signaling drives multiple myeloma induced osteoclastogenesis.

JAG2 JAG1

2.16e-06330225257302
Pubmed

Notch ligands, Delta-1 and Delta-4 suppress the self-renewal capacity and long-term growth of two myeloblastic leukemia cell lines.

DLL1 JAG1

2.16e-06330212684674
Pubmed

Reducing Jagged 1 and 2 levels prevents cerebral arteriovenous malformations in matrix Gla protein deficiency.

JAG2 JAG1

2.16e-06330224191040
Pubmed

Activation of Notch signal pathway is associated with a poorer prognosis in acute myeloid leukemia.

DLL1 JAG1

2.16e-06330220812035
Pubmed

Both Notch1 and its ligands in B cells promote antibody production.

DLL1 JAG1

2.16e-06330228863329
Pubmed

Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development.

DLL1 JAG1

2.16e-0633028923452
Pubmed

A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling.

DLL1 JAG1

2.16e-06330212482954
Pubmed

Cancer stem cell and embryonic development-associated molecules contribute to prognostic significance in ovarian cancer.

DLL1 JAG1

2.16e-06330222080880
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN8A

2.16e-06330232845893
Pubmed

Notch signaling regulates arterial vasoreactivity through opposing functions of Jagged1 and Dll4 in the vessel wall.

DLL1 JAG1

2.16e-06330230168730
Pubmed

Jagged-1 Signaling in the Bone Marrow Microenvironment Promotes Endothelial Progenitor Cell Expansion and Commitment of CD133+ Human Cord Blood Cells for Postnatal Vasculogenesis.

DLL1 JAG1

2.16e-06330227846321
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN8A

2.16e-06330228518218
Pubmed

Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.

SCN1A SCN8A

2.16e-06330224704313
Pubmed

Transmission of survival signals through Delta-like 1 on activated CD4+ T cells.

DLL1 JAG1

2.16e-06330227659682
Pubmed

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions.

JAG2 DLL1

2.16e-06330221372153
InteractionLGALS1 interactions

KCNMA1 JAG2 LRP2 CYLD TENM3 JAG1

8.13e-06332306int:LGALS1
InteractionCLU interactions

LRP2 FXR1 LTF TENM3 TXNDC11

2.83e-05245305int:CLU
InteractionTHBS1 interactions

LRP2 CYLD FGG JAG1

3.63e-05127304int:THBS1
InteractionSCN4B interactions

SCN1A SCN8A

5.96e-058302int:SCN4B
InteractionMFAP5 interactions

JAG2 DLL1 JAG1

6.26e-0552303int:MFAP5
InteractionMAGI1 interactions

KCNMA1 LRP2 DLL1 ADGRB1

6.42e-05147304int:MAGI1
InteractionGPRASP1 interactions

LRP2 FXR1 GRM1

1.34e-0467303int:GPRASP1
InteractionMFAP2 interactions

JAG2 JAG1

1.40e-0412302int:MFAP2
InteractionATN1 interactions

JAG2 LRP2 FXR1 SLIT1

1.63e-04187304int:ATN1
Cytoband16q12.1

CYLD ADCY7

2.29e-043430216q12.1
Cytoband3p21.31

LTF TCAIM

1.96e-031003023p21.31
CytobandEnsembl 112 genes in cytogenetic band chr16q12

CYLD ADCY7

2.08e-03103302chr16q12
CytobandEnsembl 112 genes in cytogenetic band chr2q24

LY75 SCN1A

3.14e-03127302chr2q24
CytobandEnsembl 112 genes in cytogenetic band chr10q22

KCNMA1 PSAP

8.17e-03208302chr10q22
CytobandEnsembl 112 genes in cytogenetic band chr3p21

LTF TCAIM

1.81e-02316302chr3p21
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN8A

3.36e-0591821203
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SCARF1 LY75

3.24e-04271821253
GeneFamilyEndogenous ligands

FGG PSAP

2.28e-02237182542
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 DLL1 JAG1

7.50e-0716303M2207
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 DLL1 JAG1

7.50e-0716303MM1296
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

KCNMA1 GRM1 ADCY7 SLIT1 SCN8A ADGRB1

8.89e-06438306M1954
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

KCNMA1 GRM1 ADCY7 SLIT1 SCN8A ADGRB1

9.13e-06440306MM832
CoexpressionHALLMARK_WNT_BETA_CATENIN_SIGNALING

JAG2 DLL1 JAG1

1.51e-0542303M5895
CoexpressionGSE13887_RESTING_VS_NO_TREATED_CD4_TCELL_UP

SCARF1 JAG2 SEC16B FGG

1.86e-05139304M485
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

KCNMA1 JAG2 CYLD GRM1 NRXN1 SCN1A SCN8A ADGRB1

2.50e-051106308M39071
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2A

LRP2 PSAP NRXN1 SCN1A JAG1 SLIT1

5.22e-05600306M39055
CoexpressionXIE_TRASTUZUMAB_CARDIOTOXICITY_MMU_MIR_3095_3P_GENES

SEC16B AHCYL2 ADCY7

6.17e-0567303MM17499
CoexpressionGSE30083_SP1_VS_SP4_THYMOCYTE_DN

OAS2 ALS2 LY75 ADCY7

7.72e-05200304M5030
CoexpressionSASAKI_TARGETS_OF_TP73_AND_TP63

JAG2 JAG1

8.30e-0512302M17374
CoexpressionCAIRO_LIVER_DEVELOPMENT_DN

CYLD LTF FGG PSAP

1.22e-04225304M6175
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBGABA

KCNMA1 JAG2 NRXN1 SCN1A SCN8A ADGRB1

1.25e-04703306M39070
CoexpressionCAIRO_LIVER_DEVELOPMENT_DN

CYLD LTF FGG PSAP

1.53e-04239304MM1274
ToppCellAT2_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

LRP2 AHCYL2 LTF FGG CXCL17 SCN1A

3.55e-09197306fd7bdfa6bf5966ebc11fdd13915769429540ddbf
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 OAS2 LTF DLL1

1.54e-0718730503de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCellBiopsy_Other_PF-Epithelial-AT2|Biopsy_Other_PF / Sample group, Lineage and Cell type

LRP2 AHCYL2 FGG CXCL17 SCN1A

2.10e-071993059a65acfe9bf500db72142469cf17bf0973540001
ToppCellBiopsy_IPF-Epithelial-AT2|Biopsy_IPF / Sample group, Lineage and Cell type

LRP2 AHCYL2 FGG CXCL17 SCN1A

2.10e-07199305c841d475703d3489161fb7904526bd7563d5fb0f
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRP2 AHCYL2 FGG CXCL17 SCN1A

2.15e-07200305b535323e18d9fb0dde1e0026df142c831e48c29f
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

LRP2 AHCYL2 FGG CXCL17 SCN1A

2.15e-07200305cf1991853e10c562edae9a0d71a209f35b07db80
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRP2 AHCYL2 FGG CXCL17 SCN1A

2.15e-072003057618ae284625c5c121bcc00eb9f07e5b1e3adf23
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRP2 AHCYL2 FGG CXCL17 SCN1A

2.15e-07200305eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

LRP2 AHCYL2 FGG CXCL17 SCN1A

2.15e-0720030523b319bf7e5ae03e5baa777c951da9bfc97cca8c
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

LRP2 AHCYL2 FGG CXCL17 SCN1A

2.15e-07200305acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

LRP2 AHCYL2 FGG CXCL17 SCN1A

2.15e-07200305ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SEC16B LTF NRXN1 JAG1

4.03e-061613043e5a125a25d55bf27652f456239b00b315d54d91
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

KCNMA1 GRM1 ZNF786 SCN1A

4.65e-061673049efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

KCNMA1 GRM1 ZNF786 SCN1A

4.65e-06167304904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like|GI_small-bowel / Manually curated celltypes from each tissue

SCARF1 FGG DLL1 JAG1

4.77e-06168304d02eba7ece17edcdd47fd6b784c93910ce61090f
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP2 AHCYL2 FGG CXCL17

6.98e-061853047460387f48f33674330bd53b759681b264228f5a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 GRM1 SCN1A SCN8A

7.28e-061873047b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC16B PSAP NRXN1 TENM3

7.43e-06188304a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 GRM1 SCN1A SCN8A

7.43e-061883041efbc99bcd6542e5d9fa91edb7c4295167914786
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRM1 SCN1A SCN8A ADGRB1

8.24e-06193304be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRM1 SCN1A SCN8A ADGRB1

8.24e-061933040c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRM1 SCN1A SCN8A ADGRB1

8.24e-061933048689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 LTF DLL1

8.41e-06194304efd5efed060edb7f24d59600981bb60ec28ac2ef
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP2 AHCYL2 CXCL17 SCN1A

8.58e-06195304d9694db6bf239636d1335016878c98f6ee2eb0eb
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP2 AHCYL2 CXCL17 SCN1A

8.58e-061953046617abca0009ad3d8731f515f91ab275f9ea4c40
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP2 AHCYL2 CXCL17 SCN1A

8.58e-06195304fc0ae145a2118df7cbbc9ac4ca9dc12d26c087c4
ToppCell(7)_Epithelial-B_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

LRP2 FGG CXCL17 SCN1A

8.76e-06196304345d4cc062b43bca9d506fbf23363469a9ba496f
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNMA1 NRXN1 SCN1A SCN8A

9.12e-06198304c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KCNMA1 NRXN1 SLIT1 SCN8A

9.12e-061983048f25e8dff42bad8e779ca618bdb1cb1610667962
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KCNMA1 NRXN1 SLIT1 SCN8A

9.12e-06198304e3e0aa3ef20b2370f5b133048510677aaa562dfa
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNMA1 NRXN1 SCN1A SCN8A

9.12e-061983046d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNMA1 NRXN1 SCN1A SCN8A

9.12e-061983048ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNMA1 NRXN1 SCN1A SCN8A

9.12e-061983044ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRP2 FGG CXCL17 SCN1A

9.30e-06199304a38a981cffa61c8444a980916de7414e689a1b63
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_alveolar-AT2|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LRP2 AHCYL2 CXCL17 SCN1A

9.30e-06199304fa5ddba3ac1ebe712cd4cdc3f20339f7c715d039
ToppCelldistal-Epithelial-Signaling_Alveolar_Epithelial_Type_2-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AHCYL2 FGG CXCL17 SCN1A

9.49e-06200304f47bb79202a59404e4916993a1f59cffcf710320
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LRP2 AHCYL2 FGG CXCL17

9.49e-0620030495b9cc2d6f18d8c3ece933e5537c16e1b7137b34
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRP2 FGG CXCL17 SCN1A

9.49e-0620030423088edc62bf7d4db890937bfd7925dc316fcc76
ToppCelldistal-Epithelial-Signaling_Alveolar_Epithelial_Type_2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

AHCYL2 FGG CXCL17 SCN1A

9.49e-06200304b0e5c8b425f47833cdc00b5aa3734c8c980f0967
ToppCellParenchymal-NucSeq-Stromal-Schwann|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEC16B GRM1 NRXN1

9.67e-051333038819fd897b97812355e1709fcc42754522d5fb27
ToppCellParenchymal-NucSeq-Stromal-Schwann-Schwann_nonmyelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEC16B GRM1 NRXN1

9.67e-05133303b4e68a9a223e5188f1a00c7dc9bb2d675cde1d40
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP2 GRM1 NRXN1

1.10e-04139303a1945b07f177cde40e7eea03a19236ce76165857
ToppCellControl-Fibroblasts-Mesothelial_FB|Control / group, cell type (main and fine annotations)

LTF NRXN1 TENM3

1.10e-04139303e769beb031b262dd92c9605b07dbf3c29fb82520
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OAS2 ALS2 LTF

1.25e-04145303ab0e254a8d01021619853a6c175f620ccef217d8
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OAS2 ALS2 LTF

1.25e-041453032beb4ea3838796c580076ab7769de877a3a0552c
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

GRM1 NRXN1 SCN1A

1.27e-04146303c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell10x5'-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3|bone_marrow / Manually curated celltypes from each tissue

LRP2 DLL1 JAG1

1.52e-0415530383430a64c2cb5ad29caa3dacba76c28dd204ac40
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 TENM3 SLIT1

1.61e-04158303e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 TENM3 SLIT1

1.61e-04158303d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FGG CXCL17 SCN1A

1.80e-04164303b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FGG CXCL17 SCN1A

1.80e-041643033aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCellClub-club-12|World / Class top

OAS2 LTF CXCL17

1.83e-041653039b7a31cbdcd2f96b8bd08a4cd4141b92bd5e9062
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

DSEL DLL1 JAG1

1.86e-04166303773673a5d0430640439845b264740bfbbdad0cb2
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SEC16B LTF NRXN1

1.93e-041683036501495b7ad252af330b18011696c43031541018
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

FGG CXCL17 SCN1A

1.93e-04168303e20e1936573fdde78426d7a4eb45c458d5c4dbb4
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

FGG CXCL17 SCN1A

1.93e-0416830316b517e3159ad6e6d25fd48f7d5f46e77b2b318d
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AHCYL2 LTF CXCL17

1.96e-04169303a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCell10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

SCARF1 DLL1 JAG1

2.00e-0417030397df5ffb328196c46568975d2d97722bcc753bf5
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor-MUC5AC+ASCL1+_intermediate_|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

DLL1 CXCL17 ADCY7

2.00e-04170303d6e244725b21592c6056b9c443aac090f1eae836
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JAG2 DLL1 JAG1

2.00e-0417030355fe16d98ea284d05fb899888e4569c685644c7b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRM1 TENM3 SLIT1

2.14e-04174303bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GRM1 TENM3 JAG1

2.14e-04174303778e0317c0c63fa4efd74114feb760975b819d92
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNMA1 DLL1 SCN8A

2.17e-04175303019ea30ac55748463d7917abf3d3f0e804189bfd
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FGG DLL1 TENM3

2.21e-0417630327e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCell(03)_Secretory|World / shred by cell type and Timepoint

AHCYL2 LTF CXCL17

2.21e-04176303cb7b1945788196ca79007f0768b6576ec885a0e5
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KCNMA1 LTF CXCL17

2.25e-04177303a4c001a8e44142babf9f24dfe6f7b73a70b11b16
ToppCellwk_15-18-Epithelial-PNS-Schwann_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NRXN1 SCN1A SCN8A

2.25e-041773035357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L5_RORB_LINC01202|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC16B GRM1 SLIT1

2.25e-04177303b6476a91abd06b8271b4d0ad7431d24b44022b47
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRM1 TENM3 SLIT1

2.25e-04177303f30d757ee8db7e10d547498dab6560473c6ed7c0
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 LTF DSEL

2.25e-041773033a85aa2bf3f2fdbea57d22d68e022cb3f6c2eb65
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KCNMA1 LTF CXCL17

2.25e-04177303363e07b0f347f3716d530a28ead854b98e27d37c
ToppCellCOPD-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

KCNMA1 JAG2 JAG1

2.29e-04178303441d1dba720141891b11f404744c59834d80e6c5
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LTF NRXN1 CXCL17

2.29e-04178303fb8f8d95f6b08378fb42c4076ee040276faa296f
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LTF NRXN1 CXCL17

2.29e-04178303b89c4d015b44bf538aa39969ef8778877c8023f1
ToppCell390C-Epithelial_cells-Epithelial-B_(AT2)|390C / Donor, Lineage, Cell class and subclass (all cells)

LRP2 FGG CXCL17

2.32e-04179303466da2bc3bfc534ffe111c8c28ece7a3cfa08051
ToppCell390C-Epithelial_cells-Epithelial-B_(AT2)-|390C / Donor, Lineage, Cell class and subclass (all cells)

LRP2 FGG CXCL17

2.32e-04179303f4bdebb77d39e63160fbf3a85a340ce4d52b7cfd
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRM1 TENM3 SLIT1

2.32e-04179303747a32460b257fffca30527b56a74720eb9c12e4
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRM1 TENM3 SLIT1

2.32e-041793031ac79c82c52fa95bb4e170ab20fec0f648db2134
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 LTF

2.32e-04179303040a7e916baaf81f44339dc721ab2afcd2c22388
ToppCell10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-ILC_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

DLL1 JAG1 SCN8A

2.36e-0418030327672ac6a02172a31851f18decb9acffa8f5a703
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

LRP2 AHCYL2 SCN1A

2.36e-04180303198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 GRM1 SCN1A

2.36e-04180303d76349ecef7c5878bf215e946f032264161eb61b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 GRM1 SCN1A

2.36e-041803033d54cc767e25d91ed2203d8a03e5bf5e15f21699
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 JAG2 OAS2

2.36e-041803037d4cb0ab9f96088cbc5db3096d884a1e5ce4cb5d
ToppCellwk_15-18-Hematologic-Myeloid-APOE+_Mac2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KCNMA1 OAS2 FGG

2.36e-04180303c630a121aedd09a51ea18cc6e8552eb979e5b555
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRM1 TENM3 SLIT1

2.40e-041813039de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
ToppCellBasal|World / shred by cell class for mouse tongue

JAG2 DLL1 SLIT1

2.48e-04183303c6729a207526ff4aa48176207b9353176f631fea
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

LRP2 FGG CXCL17

2.48e-041833038e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 GRM1 NRXN1

2.52e-04184303ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 GRM1 NRXN1

2.52e-041843032cbed6462fea2622871bb7e49b0df3d984239281
ToppCellSerous|World / shred by cell class for bronchial biopsy

KCNMA1 LTF CXCL17

2.52e-0418430309d0d1525c11dd326efd942684c03f79d992cf3b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 GRM1 NRXN1

2.52e-041843032b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

FGG CXCL17 SCN1A

2.52e-041843030ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-neuroendocrine_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRXN1 SCN8A ADGRB1

2.52e-04184303e0e5a553fb8c0947679634396d20c2ca8455b932
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

LRP2 CXCL17 SCN1A

2.52e-04184303369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-neuroendocrine_cell-neuroendocrine|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NRXN1 SCN8A ADGRB1

2.52e-04184303c3b848e1438a84b3fac8a4e40f3db478cc84d970
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRM1 SCN1A SCN8A

2.52e-041843037d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

FGG CXCL17 SCN1A

2.52e-041843032a8338e94937686a148b5433515700ca0f674058
ToppCelldroplet-Limb_Muscle-nan-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN1 ZNF786 ADGRB1

2.52e-04184303a7399a72f065d68800e3e0b2031d9894e0cc0ba4
ToppCellPBMC-Mild-cDC_9|Mild / Compartment, Disease Groups and Clusters

OAS2 PSAP SCN8A

2.52e-041843032e0c9a2c40c892a2d435eafb31f1f838de9baf15
Diseasetemporal arteritis (is_marker_for)

DLL1 JAG1

1.95e-057292DOID:13375 (is_marker_for)
DiseaseCOVID-19, mortality

KCNMA1 LRP2 FXR1 TENM3

2.26e-05170294EFO_0004352, MONDO_0100096
Diseaseplasma renin activity measurement

TENM3 TXNDC11

3.34e-059292EFO_0006828
DiseasePetit mal status

KCNMA1 GRM1 SCN8A

3.92e-0567293C0270823
DiseaseGrand Mal Status Epilepticus

KCNMA1 GRM1 SCN8A

3.92e-0567293C0311335
DiseaseStatus Epilepticus, Subclinical

KCNMA1 GRM1 SCN8A

3.92e-0567293C0751522
DiseaseSimple Partial Status Epilepticus

KCNMA1 GRM1 SCN8A

3.92e-0567293C0751524
DiseaseNon-Convulsive Status Epilepticus

KCNMA1 GRM1 SCN8A

3.92e-0567293C0751523
DiseaseComplex Partial Status Epilepticus

KCNMA1 GRM1 SCN8A

3.92e-0567293C0393734
DiseaseStatus Epilepticus

KCNMA1 GRM1 SCN8A

4.10e-0568293C0038220
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN8A

4.18e-0510292DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN8A

4.18e-0510292DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN8A

6.12e-0512292DOID:0060170 (implicated_via_orthology)
Diseasedilated cardiomyopathy (implicated_via_orthology)

JAG2 DLL1 JAG1

6.66e-0580293DOID:12930 (implicated_via_orthology)
DiseaseIntellectual Disability

LRP2 DLL1 NRXN1 SCN1A SCN8A

6.86e-05447295C3714756
DiseaseEpilepsy, Cryptogenic

GRM1 SCN1A SCN8A

7.17e-0582293C0086237
DiseaseAwakening Epilepsy

GRM1 SCN1A SCN8A

7.17e-0582293C0751111
DiseaseAura

GRM1 SCN1A SCN8A

7.17e-0582293C0236018
DiseaseMetabolic Bone Disorder

KCNMA1 LRP2

8.43e-0514292C0005944
DiseaseOsteopenia

KCNMA1 LRP2

9.72e-0515292C0029453
DiseaseMental Depression

OAS2 GRM1 NRXN1 ADCY7

1.08e-04254294C0011570
Diseasebipolar disorder, sex interaction measurement

SLIT1 ADGRB1

1.41e-0418292EFO_0008343, MONDO_0004985
DiseaseEpilepsy

GRM1 SCN1A SCN8A

1.67e-04109293C0014544
DiseaseDepressive disorder

OAS2 GRM1 NRXN1 ADCY7

1.76e-04289294C0011581
DiseaseSchizophrenia

JAG2 LRP2 GRM1 NRXN1 ADCY7 JAG1

1.86e-04883296C0036341
DiseaseCarcinoma, Pancreatic Ductal

JAG2 JAG1

2.54e-0424292C0887833
DiseaseMental Retardation, Psychosocial

NRXN1 SCN1A SCN8A

3.42e-04139293C0025363
DiseaseProfound Mental Retardation

NRXN1 SCN1A SCN8A

3.42e-04139293C0020796
DiseaseMental deficiency

NRXN1 SCN1A SCN8A

3.42e-04139293C0917816
Diseaseautism spectrum disorder (implicated_via_orthology)

FXR1 NRXN1 SCN1A

4.44e-04152293DOID:0060041 (implicated_via_orthology)
DiseaseCraniofacial Abnormalities

JAG2 LRP2 NRXN1

4.79e-04156293C0376634
Diseaseepilepsy (implicated_via_orthology)

KCNMA1 SCN1A SCN8A

5.44e-04163293DOID:1826 (implicated_via_orthology)
DiseaseDiaphragmatic Hernia

KCNMA1 LRP2

7.47e-0441292C0019284
Diseaseresponse to xenobiotic stimulus

NRXN1 TENM3 SCN1A

7.49e-04182293GO_0009410
Diseasewaist circumference

SEC16B GRM1 NRXN1 SLIT1

7.85e-04429294EFO_0004342

Protein segments in the cluster

PeptideGeneStartEntry
CEGPGQGEVWKAWDN

ALS2

1306

Q96Q42
LQQCPVDGKWQAWAS

ADGRB1

516

O14514
LSPCWQWDCCGQGLG

ADCY7

761

P51828
NIPSWNWKEGDDAIC

KCNMA1

536

Q12791
ANDQEPCGWWLAKVR

FXR1

71

P51114
WQCNCETNWGGLLCD

JAG2

291

Q9Y219
KPQWECRENSGNLWA

C9orf131

411

Q5VYM1
WGICLKPENGCEDNW

LY75

206

O60449
NNEKCIPIWWKCDGQ

LRP2

3521

P98164
AEGQWTRFPKWNACC

NRXN1

36

Q9ULB1
DPTNNVSGDKICWQW

OAS2

296

P29728
NCAEQDGSGWWMNKC

FGG

351

P02679
PWQCNCQEGWGGLFC

DLL1

271

O00548
RWLQEGGQECECKDW

CXCL17

41

Q6UXB2
DWDWRHGCIPCQNME

CYLD

846

Q9NQC7
TCKACDLGWWPNADL

GRM1

561

Q13255
CNKPWEGQLGECAQW

DSEL

511

Q8IZU8
CNEPWQCLCETNWGG

JAG1

276

P78504
WGNQIWICPGCNKPD

TAF3

861

Q5VWG9
GDLCIPWNWKNGEAI

TCAIM

481

Q8N3R3
WCIDRCVNVEGWQPN

AHCYL2

291

Q96HN2
WCAVGEQELRKCNQW

LTF

366

P02788
RPGWWGPECQQQCEC

SCARF1

211

Q14162
CCQINVEEGRGKQWW

SCN1A

1191

P35498
CCQVNIEEGLGKSWW

SCN8A

1171

Q9UQD0
DQNGWHCVCQPGWRG

TENM3

756

Q9P273
GTEKCIWGPSYWCQN

PSAP

491

P07602
PQAATCCGEKQWGDW

SEC16B

511

Q96JE7
VAINCWWNQGKCRKQ

TXNDC11

161

Q6PKC3
QHPWPVCGESCWENN

ZNF786

186

Q8N393
NPFNCNCQLAWLGGW

SLIT1

671

O75093
CSWNREEPGEQWNKI

nan

16

Q8N9L7