Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3K14 acetyltransferase activity	BRPF3 KAT6A KAT6B	1.06e-05	9	102	3	GO:0036408
GeneOntologyMolecularFunction	histone H3 acetyltransferase activity	BRPF3 KAT6A KAT6B	5.63e-05	15	102	3	GO:0010484
GeneOntologyCellularComponent	MOZ/MORF histone acetyltransferase complex	BRPF3 KAT6A KAT6B	3.67e-06	7	100	3	GO:0070776
GeneOntologyCellularComponent	H3 histone acetyltransferase complex	BRPF3 KAT6A KAT6B	5.85e-06	8	100	3	GO:0070775
GeneOntologyCellularComponent	costamere	DAG1 CMYA5 AHNAK2	1.53e-04	22	100	3	GO:0043034
GeneOntologyCellularComponent	super elongation complex	AFF1 AFF4	3.36e-04	6	100	2	GO:0032783
GeneOntologyCellularComponent	ribbon synapse	AMPH PCLO DAG1	4.76e-04	32	100	3	GO:0097470
HumanPheno	Laryngomalacia	PPM1D KAT6A CHD7 ASXL3 KAT6B AFF4	8.89e-06	84	31	6	HP:0001601
HumanPheno	Highly arched eyebrow	RPGRIP1L KAT6A CHD8 CHD7 ZNF462 ASXL3 SPEN AFF4	2.21e-05	206	31	8	HP:0002553
Domain	Chromodomain-like	ARID4B CHD8 CHD7 CBX4 CBX6	6.79e-07	32	99	5	IPR016197
Domain	Chromo/shadow_dom	ARID4B CHD8 CHD7 CBX4 CBX6	7.97e-07	33	99	5	IPR000953
Domain	CHROMO	ARID4B CHD8 CHD7 CBX4 CBX6	7.97e-07	33	99	5	SM00298
Domain	Chromo_domain	CHD8 CHD7 CBX4 CBX6	7.27e-06	24	99	4	IPR023780
Domain	Chromo	CHD8 CHD7 CBX4 CBX6	1.02e-05	26	99	4	PF00385
Domain	ZF_PHD_2	BRPF3 KAT6A ASH1L CXXC1 ASXL3 KAT6B	1.13e-05	95	99	6	PS50016
Domain	ZF_PHD_1	BRPF3 KAT6A ASH1L CXXC1 ASXL3 KAT6B	1.20e-05	96	99	6	PS01359
Domain	Znf_FYVE_PHD	BRPF3 PCLO KAT6A ASH1L CXXC1 KAT6B FGD3	1.32e-05	147	99	7	IPR011011
Domain	CHROMO_1	CHD8 CHD7 CBX4 CBX6	1.38e-05	28	99	4	PS00598
Domain	CHROMO_2	CHD8 CHD7 CBX4 CBX6	1.38e-05	28	99	4	PS50013
Domain	H15	KAT6A HP1BP3 KAT6B	3.98e-05	13	99	3	SM00526
Domain	H15	KAT6A HP1BP3 KAT6B	3.98e-05	13	99	3	PS51504
Domain	PHD	BRPF3 KAT6A ASH1L CXXC1 KAT6B	4.86e-05	75	99	5	PF00628
Domain	Histone_H1/H5_H15	KAT6A HP1BP3 KAT6B	5.04e-05	14	99	3	IPR005818
Domain	Znf_PHD-finger	BRPF3 KAT6A ASH1L CXXC1 KAT6B	6.24e-05	79	99	5	IPR019787
Domain	PHD	BRPF3 KAT6A ASH1L CXXC1 KAT6B	1.10e-04	89	99	5	SM00249
Domain	Znf_PHD	BRPF3 KAT6A ASH1L CXXC1 KAT6B	1.23e-04	91	99	5	IPR001965
Domain	PDZ	PCLO CNKSR2 RGS3 SHROOM4 ARHGAP21 AHNAK2	1.53e-04	151	99	6	PS50106
Domain	PDZ	PCLO CNKSR2 RGS3 SHROOM4 ARHGAP21 AHNAK2	1.58e-04	152	99	6	IPR001478
Domain	TF_AF4/FMR2	AFF1 AFF4	1.66e-04	4	99	2	IPR007797
Domain	AF-4	AFF1 AFF4	1.66e-04	4	99	2	PF05110
Domain	-	IRS4 APBB2 CNKSR2 CIT RGS3 DEF6 PLEKHO1 ARHGAP21 FGD3	2.32e-04	391	99	9	2.30.29.30
Domain	MOZ_SAS	KAT6A KAT6B	2.75e-04	5	99	2	PF01853
Domain	HAT_MYST-type	KAT6A KAT6B	2.75e-04	5	99	2	IPR002717
Domain	CBX7_C	CBX4 CBX6	2.75e-04	5	99	2	IPR033773
Domain	CBX7_C	CBX4 CBX6	2.75e-04	5	99	2	PF17218
Domain	MYST_HAT	KAT6A KAT6B	2.75e-04	5	99	2	PS51726
Domain	-	CUX2 POU6F1 CUX1	3.85e-04	27	99	3	1.10.260.40
Domain	AT_hook	AHCTF1 ASH1L PRR12	3.85e-04	27	99	3	SM00384
Domain	AT_hook_DNA-bd_motif	AHCTF1 ASH1L PRR12	3.85e-04	27	99	3	IPR017956
Domain	BRK	CHD8 CHD7	4.11e-04	6	99	2	SM00592
Domain	BRK_domain	CHD8 CHD7	4.11e-04	6	99	2	IPR006576
Domain	BRK	CHD8 CHD7	4.11e-04	6	99	2	PF07533
Domain	PH_dom-like	IRS4 APBB2 CNKSR2 CIT RGS3 DEF6 PLEKHO1 ARHGAP21 FGD3	4.34e-04	426	99	9	IPR011993
Domain	Lambda_DNA-bd_dom	CUX2 POU6F1 CUX1	4.78e-04	29	99	3	IPR010982
Domain	CUT	CUX2 CUX1	5.74e-04	7	99	2	PS51042
Domain	CUT	CUX2 CUX1	5.74e-04	7	99	2	PF02376
Domain	CUT_dom	CUX2 CUX1	5.74e-04	7	99	2	IPR003350
Domain	CUT	CUX2 CUX1	5.74e-04	7	99	2	SM01109
Domain	PH	IRS4 CNKSR2 CIT DEF6 PLEKHO1 ARHGAP21 FGD3	6.96e-04	278	99	7	SM00233
Domain	PH_DOMAIN	IRS4 CNKSR2 CIT DEF6 PLEKHO1 ARHGAP21 FGD3	7.11e-04	279	99	7	PS50003
Domain	PH_domain	IRS4 CNKSR2 CIT DEF6 PLEKHO1 ARHGAP21 FGD3	7.26e-04	280	99	7	IPR001849
Domain	RGS	RGS3 RGS7 SNX14	8.36e-04	35	99	3	PF00615
Domain	RGS	RGS3 RGS7 SNX14	8.36e-04	35	99	3	SM00315
Domain	RGS	RGS3 RGS7 SNX14	9.08e-04	36	99	3	PS50132
Domain	PDZ	CNKSR2 RGS3 SHROOM4 ARHGAP21 AHNAK2	9.25e-04	141	99	5	PF00595
Domain	PDZ	CNKSR2 RGS3 SHROOM4 ARHGAP21 AHNAK2	1.15e-03	148	99	5	SM00228
Domain	RGS	RGS3 RGS7 SNX14	1.15e-03	39	99	3	IPR016137
Domain	Chromo_dom_subgr	CBX4 CBX6	1.22e-03	10	99	2	IPR017984
Domain	-	CNKSR2 RGS3 SHROOM4 ARHGAP21 AHNAK2	1.22e-03	150	99	5	2.30.42.10
Domain	PH	CNKSR2 CIT DEF6 PLEKHO1 ARHGAP21 FGD3	1.38e-03	229	99	6	PF00169
Domain	Linker_histone	HP1BP3 KAT6B	2.09e-03	13	99	2	PF00538
Domain	CNH	TNIK CIT	2.43e-03	14	99	2	SM00036
Domain	CNH	TNIK CIT	2.79e-03	15	99	2	PF00780
Domain	CNH	TNIK CIT	2.79e-03	15	99	2	PS50219
Domain	CNH_dom	TNIK CIT	2.79e-03	15	99	2	IPR001180
Domain	AT_hook	AHCTF1 PRR12	3.18e-03	16	99	2	PF02178
Domain	Chromodomain_CS	CBX4 CBX6	4.03e-03	18	99	2	IPR023779
Domain	Zinc_finger_PHD-type_CS	BRPF3 ASH1L CXXC1	4.97e-03	65	99	3	IPR019786
Domain	C2	RPGRIP1L PCLO RAB11FIP1 RGS3	5.21e-03	131	99	4	PF00168
Pathway	REACTOME_HATS_ACETYLATE_HISTONES	BRPF3 KAT6A MSL1 KAT6B	6.17e-05	46	66	4	MM14935
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	BRPF3 ARID4B KAT6A ASH1L MSL1 KAT6B	1.65e-04	175	66	6	MM14941
Pathway	KEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119	CBX4 CBX6 ASXL3	2.36e-04	26	66	3	M47923
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ARID4B AHCTF1 KAT6A CHD8 MSL1 CHD7 CBX4 XRCC1 HP1BP3 IWS1 ZNF512B ZNF462 UBE2O ZNF592 FAM169A SPEN CUX1 AFF4 KPNA1	1.60e-14	608	102	19	36089195
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	HAUS6 IRS4 UBR4 CHD8 CHD7 PPP6R1 BIRC6 ZNF462 PRR12 MRTFB ZNF592 ARHGAP21 CUX1	3.22e-10	418	102	13	34709266
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ZNF777 IRS4 ARID4B SEPTIN9 AHCTF1 CHD8 MSL1 CHD7 CBX4 XRCC1 HP1BP3 ZNF512B MED19 SIMC1 SPEN CUX1 AFF4	2.64e-09	954	102	17	36373674
Pubmed	Human transcription factor protein interaction networks.	IRS4 ARID4B UBR4 PPP1R13B CHD8 MSL1 CHD7 PPP6R1 XRCC1 CIT CXXC1 HP1BP3 ZNF512B ZNF462 PRR12 UBE2O ZNF592 PRKCSH SPEN CUX1	5.50e-09	1429	102	20	35140242
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	TBC1D30 AHCTF1 CHD8 MSL1 CHD7 CBX4 XRCC1 RAB11FIP1 CIT IWS1 PRR12 MED19 MRTFB ZNF592 PALM3 PAK1IP1 SPEN EDRF1 AFF4 KPNA1	1.20e-08	1497	102	20	31527615
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	TNIK CUX2 KIAA0232 CHD8 CHD7 BIRC6 ZNF462 MRTFB KAT6B	2.30e-08	225	102	9	12168954
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ZNF777 BRPF3 BIRC6 ZNF512B SHROOM4 PRR12 MRTFB	2.38e-08	103	102	7	10574462
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	HAUS6 ARID4B MSL1 CBX4 XRCC1 IWS1 ZNF512B UBE2O MED19 ZNF592 FAM169A SPEN EDRF1	5.63e-08	645	102	13	25281560
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	PPM1D UBR4 CHD8 CBX4 XRCC1 HP1BP3 MRTFB KAT6B SPEN AFF4	6.90e-08	341	102	10	32971831
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TNIK HAUS6 IRS4 SEPTIN9 AHCTF1 RTN4 PPP6R1 HP1BP3 ZNF512B UBE2O MRTFB FAM169A ARHGAP21 AFF4 AHNAK2	9.67e-08	934	102	15	33916271
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	UBR4 CHD8 MSL1 CHD7 PPP6R1 CBX4 ZNF462 SPEN CUX1	1.58e-07	282	102	9	23667531
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	TNIK SEPTIN9 AHCTF1 PCLO RTN4 UBR4 XRCC1 HP1BP3 VCAN ARHGAP21 KPNA1	2.57e-07	498	102	11	36634849
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	KAT6A ASH1L CHD8 CHD7 CBX4 CBX6 KAT6B	4.31e-07	157	102	7	30186101
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	TNIK IRS4 APBB2 DAG1 PPP1R13B RAB11FIP1 RGS7 PTPRM PRKCSH ARHGAP21	4.80e-07	421	102	10	36976175
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	CUX2 IRS4 UBR4 CNKSR2 CHD7 MRTFB XIRP2 AFF1 SPEN PLEKHO1	5.82e-07	430	102	10	35044719
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	RPGRIP1L TBC1D30 SEPTIN9 CPEB3 CIT SPEN	5.88e-07	102	102	6	10231032
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	UBR4 KAT6A CHD8 PPP6R1 BIRC6 CIT MICALL1 PRR12 ZNF592 DEF6 TMEM132A SNX11 SPEN ARHGAP21 AHNAK2	8.15e-07	1105	102	15	35748872
Pubmed	Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.	BRPF3 KAT6A KAT6B	8.50e-07	7	102	3	18794358
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TNIK SGIP1 UBR4 CHD8 CNKSR2 CHD7 PPP6R1 CIT ZNF462 UBE2O ARHGAP21 CUX1 AFF4 KPNA1	8.80e-07	963	102	14	28671696
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	HAUS6 IRS4 SEPTIN9 AHCTF1 PPP1R13B UBE2O ARHGAP21 AHNAK2	1.14e-06	263	102	8	34702444
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	BRPF3 ARID4B AHCTF1 KAT6A ASH1L CHD8 PPP6R1 CBX4 RAB11FIP1 ZNF512B ZNF592 KAT6B AFF4 KPNA1	4.87e-06	1116	102	14	31753913
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	TNIK AMPH SGIP1 SEPTIN9 PCLO RTN4 UBR4 DAG1 CNKSR2 PPP6R1 BIRC6 CIT UBE2O FAM169A	6.14e-06	1139	102	14	36417873
Pubmed	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.	BRPF3 ARID4B KAT6A KAT6B	7.16e-06	42	102	4	16387653
Pubmed	Impact of WIN site inhibitor on the WDR5 interactome.	CHD8 MSL1 CXXC1 ZNF462	7.88e-06	43	102	4	33472061
Pubmed	Cux1 and Cux2 selectively target basal and apical dendritic compartments of layer II-III cortical neurons.	CUX2 CUX1	8.52e-06	2	102	2	25059644
Pubmed	Cux-1 and Cux-2 control the development of Reelin expressing cortical interneurons.	CUX2 CUX1	8.52e-06	2	102	2	18327765
Pubmed	A unique variant of a homeobox gene related to Drosophila cut is expressed in mouse testis.	CUX2 CUX1	8.52e-06	2	102	2	8879483
Pubmed	Distinct roles of two SEC scaffold proteins, AFF1 and AFF4, in regulating RNA polymerase II transcription elongation.	AFF1 AFF4	8.52e-06	2	102	2	37528066
Pubmed	CUX2 deficiency causes facilitation of excitatory synaptic transmission onto hippocampus and increased seizure susceptibility to kainate.	CUX2 CUX1	8.52e-06	2	102	2	35581205
Pubmed	Regulation of KAT6 Acetyltransferases and Their Roles in Cell Cycle Progression, Stem Cell Maintenance, and Human Disease.	KAT6A KAT6B	8.52e-06	2	102	2	27185879
Pubmed	CHD8 interacts with CHD7, a protein which is mutated in CHARGE syndrome.	CHD8 CHD7	8.52e-06	2	102	2	20453063
Pubmed	AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter.	AFF1 AFF4	8.52e-06	2	102	2	24843025
Pubmed	Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators.	CHD8 CHD7	8.52e-06	2	102	2	24211491
Pubmed	Expression of a cut-related homeobox gene in developing and polycystic mouse kidney.	CUX2 CUX1	8.52e-06	2	102	2	8840273
Pubmed	ERα status of invasive ductal breast carcinoma as a result of regulatory interactions between lysine deacetylases KAT6A and KAT6B.	KAT6A KAT6B	8.52e-06	2	102	2	39505971
Pubmed	Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription.	AFF1 AFF4	8.52e-06	2	102	2	26007649
Pubmed	Cux1 Enables Interhemispheric Connections of Layer II/III Neurons by Regulating Kv1-Dependent Firing.	CUX2 CUX1	8.52e-06	2	102	2	26804994
Pubmed	The double PHD finger domain of MOZ/MYST3 induces α-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.	KAT6A KAT6B	8.52e-06	2	102	2	24150941
Pubmed	Interaction network of human early embryonic transcription factors.	ARID4B CHD8 CHD7 ZNF512B ZNF462 PRR12 ASXL3 SPEN	9.56e-06	351	102	8	38297188
Pubmed	Functional proteomics mapping of a human signaling pathway.	UBR4 ASH1L PPP1R13B CBX4 RGS3 ZNF512B MRTFB ZNF592 AFF1 KPNA1	9.77e-06	591	102	10	15231748
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	RPGRIP1L AHCTF1 CHD8 CHD7 BIRC6 IWS1 ZNF462 ZNF592 SPEN	1.03e-05	469	102	9	27634302
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	IRS4 RPGRIP1L PPM1D PPP1R13B PPP6R1 XRCC1 RAB11FIP1 BIRC6 IWS1 ZNF512B PTPRM PRKCSH KPNA1	1.24e-05	1049	102	13	27880917
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	ZSCAN5A MSL1 CBX4 CXXC1 ZNF512B ZNF462 UBE2O CBX6 KPNA1	1.58e-05	495	102	9	27705803
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CUX2 IRS4 PCLO UBR4 ASH1L FAM47B MSL1 CXXC1 HP1BP3 STARD9 FAM186A FAM169A SPEN ARHGAP21 CUX1	2.01e-05	1442	102	15	35575683
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	AHCTF1 CHD8 CHD7 XRCC1 MRTFB SPEN AFF4	2.09e-05	283	102	7	30585729
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	AHCTF1 CHD8 CBX4 CXXC1 HP1BP3 SPEN	2.48e-05	195	102	6	19454010
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ARID4B ZSCAN5A AHCTF1 MSL1 CHD7 CBX4 XRCC1 CXXC1 HP1BP3 IWS1 ZNF512B PRR12 SPEN CUX1	2.55e-05	1294	102	14	30804502
Pubmed	MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain.	KAT6A KAT6B	2.55e-05	3	102	2	36754959
Pubmed	Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8.	CHD8 CHD7	2.55e-05	3	102	2	30108144
Pubmed	Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin.	KAT6A KAT6B	2.55e-05	3	102	2	23063713
Pubmed	The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.	CHD8 CHD7	2.55e-05	3	102	2	28533432
Pubmed	Autism-linked CHD gene expression patterns during development predict multi-organ disease phenotypes.	CHD8 CHD7	2.55e-05	3	102	2	30277262
Pubmed	A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice.	ZNF462 MRTFB	2.55e-05	3	102	2	1592261
Pubmed	Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling.	RPGRIP1L CUX1	2.55e-05	3	102	2	21037323
Pubmed	AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23).	AFF1 AFF4	2.55e-05	3	102	2	10588740
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TNIK SEPTIN9 KIAA0232 CNKSR2 PPP6R1 STARD9 SPEN ARHGAP21	2.76e-05	407	102	8	12693553
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SEPTIN9 KIAA0232 KAT6A ASH1L APBB2 HP1BP3 ZNF462 MRTFB ZFHX2 AFF1 LTBR KAT6B CUX1 AFF4 KPNA1	2.92e-05	1489	102	15	28611215
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	ZNF777 ZSCAN5A CHD7 ZNF462 SIMC1	3.49e-05	125	102	5	32891193
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	HAUS6 IRS4 AHCTF1 PPP1R13B CHD8 UBE2O MRTFB SPEN CUX1	3.56e-05	549	102	9	38280479
Pubmed	A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.	PPM1D MSL1 CBX4 BIRC6 UBE2O ASXL3 TMEM132A AFF1	4.14e-05	431	102	8	33660365
Pubmed	Importance of a specific amino acid pairing for murine MLL leukemias driven by MLLT1/3 or AFF1/4.	AFF1 AFF4	5.09e-05	4	102	2	25282333
Pubmed	Biochemical characterization of the mammalian Cux2 protein.	CUX2 CUX1	5.09e-05	4	102	2	15656993
Pubmed	The interaction of ETV6 (TEL) and TIP60 requires a functional histone acetyltransferase domain in TIP60.	KAT6A KAT6B	5.09e-05	4	102	2	17980166
Pubmed	A Minor Subset of Super Elongation Complexes Plays a Predominant Role in Reversing HIV-1 Latency.	AFF1 AFF4	5.09e-05	4	102	2	26830226
Pubmed	SEPT9_i1 is required for the association between HIF-1α and importin-α to promote efficient nuclear translocation.	SEPTIN9 KPNA1	5.09e-05	4	102	2	24067372
Pubmed	Identification and characterization of FAM124B as a novel component of a CHD7 and CHD8 containing complex.	CHD8 CHD7	5.09e-05	4	102	2	23285124
Pubmed	Cux1 and Cux2 regulate dendritic branching, spine morphology, and synapses of the upper layer neurons of the cortex.	CUX2 CUX1	5.09e-05	4	102	2	20510857
Pubmed	Recognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ) and MOZ-related factor (MORF).	KAT6A KAT6B	5.09e-05	4	102	2	21880731
Pubmed	Intersectin 1 forms complexes with SGIP1 and Reps1 in clathrin-coated pits.	AMPH SGIP1	5.09e-05	4	102	2	20946875
Pubmed	Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice.	AFF1 AFF4	5.09e-05	4	102	2	11923441
Pubmed	Mediation of Af4 protein function in the cerebellum by Siah proteins.	AFF1 AFF4	5.09e-05	4	102	2	15459319
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	TNIK BRPF3 RTN4 DAG1 XRCC1 RGS7 SPEN	5.44e-05	329	102	7	17474147
Pubmed	Tagging genes with cassette-exchange sites.	SEPTIN9 UBR4 CHD8 BIRC6 CIT ZNF462 KAT6B	6.10e-05	335	102	7	15741177
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	SGIP1 PCLO RTN4 CPEB3 CNKSR2 CIT RGS7	7.60e-05	347	102	7	17114649
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	HAUS6 IRS4 PPP6R1 UBE2O PAK1IP1 KPNA1	8.23e-05	242	102	6	34011540
Pubmed	Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication.	KAT6A KAT6B	8.47e-05	5	102	2	17182677
Pubmed	MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2.	KAT6A KAT6B	8.47e-05	5	102	2	11965546
Pubmed	14-3-3 interacts with regulator of G protein signaling proteins and modulates their activity.	RGS3 RGS7	8.47e-05	5	102	2	10862767
Pubmed	Primary structure, neural-specific expression, and chromosomal localization of Cux-2, a second murine homeobox gene related to Drosophila cut.	CUX2 CUX1	8.47e-05	5	102	2	8798433
Pubmed	The mouse homeodomain protein Phox2 regulates Ncam promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype.	CUX2 CUX1	8.47e-05	5	102	2	7910552
Pubmed	Nuclear localization of Duplin, a beta-catenin-binding protein, is essential for its inhibitory activity on the Wnt signaling pathway.	CHD8 KPNA1	8.47e-05	5	102	2	11744694
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	UBR4 ASH1L CHD7 STARD9 ARHGAP21	9.12e-05	153	102	5	10718198
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ARID4B SEPTIN9 CHD7 IWS1 MICALL1 ZNF592 AFF1 PAK1IP1 KAT6B SPEN	9.50e-05	774	102	10	15302935
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	IRS4 ARID4B UBR4 BIRC6 HP1BP3 PAK1IP1	1.05e-04	253	102	6	29911972
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HAUS6 TBC1D30 BIRC6 ZNF462 SHROOM4 PRR12 TMEM132A FAM169A	1.05e-04	493	102	8	15368895
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	CHD7 PRR12 SPEN CUX1	1.07e-04	83	102	4	28794006
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TNIK AHCTF1 RTN4 UBR4 PPP6R1 RAB11FIP1 HP1BP3 MICALL1 ZNF512B UBE2O PRKCSH SUCO EDRF1 CUX1	1.13e-04	1487	102	14	33957083
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	IRS4 RPGRIP1L COL15A1 AHCTF1 PCLO RTN4 UBR4 BIRC6 ZNF512B FAM169A PRKCSH SUCO CUX1 AHNAK2	1.20e-04	1496	102	14	32877691
Pubmed	Expression of Cux-1 and Cux-2 in the subventricular zone and upper layers II-IV of the cerebral cortex.	CUX2 CUX1	1.27e-04	6	102	2	15452856
Pubmed	CHARGE and Kabuki syndromes: a phenotypic and molecular link.	CHD8 CHD7	1.27e-04	6	102	2	24705355
Pubmed	USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components.	CBX4 CBX6	1.27e-04	6	102	2	28839133
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	IRS4 AHCTF1 UBR4 CHD8 CHD7 BIRC6 HP1BP3 UBE2O SPEN	1.33e-04	653	102	9	22586326
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	IRS4 SEPTIN9 PCLO RTN4 UBR4 ASH1L CHD8 HP1BP3 PRKCSH AHNAK2	1.33e-04	807	102	10	30575818
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	IRS4 RPGRIP1L AHCTF1 HP1BP3 ZNF462 PRR12 STARD9 ASXL3	1.38e-04	513	102	8	25798074
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	CHD8 CHD7 ZNF512B PRR12 CUX1 AFF4	1.44e-04	268	102	6	33640491
Pubmed	[IMAGE: molecular integration of the analysis of the human genome and its expression].	AMPH CNKSR2 ZNF462	1.50e-04	35	102	3	7757816
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	BRPF3 RTN4 CHD8 MICALL1 ZNF512B UBE2O ZNF592 KAT6B	1.71e-04	529	102	8	14621295
Pubmed	The eleven-nineteen-leukemia protein ENL connects nuclear MLL fusion partners with chromatin.	AFF1 AFF4	1.77e-04	7	102	2	15856011
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	ASH1L CHD8 CBX4 XRCC1 HP1BP3 MED19 ZNF592 CBX6	1.80e-04	533	102	8	30554943
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	TNIK HAUS6 RPGRIP1L SEPTIN9 KIAA0232 PPP1R13B MICALL1 MRTFB SIMC1 ARHGAP21	2.09e-04	853	102	10	28718761
Interaction	H2BC21 interactions	BRPF3 ARID4B PPM1D AHCTF1 PCLO KAT6A FAM47B CHD8 MSL1 CHD7 CBX4 XRCC1 HP1BP3 IWS1 PRR12 MRTFB PTPRM CBX6 KAT6B KPNA1	2.59e-10	696	102	20	int:H2BC21
Interaction	H3-3A interactions	ARID4B PPM1D AHCTF1 KAT6A ASH1L CHD8 MSL1 CHD7 CBX4 XRCC1 HP1BP3 IWS1 ZNF512B ZNF592 CBX6 SPEN CUX1 AFF4 KPNA1	5.99e-09	749	102	19	int:H3-3A
Interaction	RCOR1 interactions	TNIK HAUS6 IRS4 ZSCAN5A UBR4 CHD8 CHD7 PPP6R1 BIRC6 MRTFB ZNF592 FAM169A SPEN ARHGAP21 CUX1	2.77e-08	494	102	15	int:RCOR1
Interaction	H3C3 interactions	AHCTF1 CHD8 MSL1 CHD7 CBX4 HP1BP3 IWS1 ZNF512B ZNF462 UBE2O FAM169A SPEN CUX1 AFF4 KPNA1	2.84e-08	495	102	15	int:H3C3
Interaction	H2BC8 interactions	ARID4B AHCTF1 CHD8 MSL1 CHD7 CBX4 XRCC1 CXXC1 HP1BP3 IWS1 ZNF512B UBE2O ZNF592 FAM169A SPEN CUX1	3.15e-08	576	102	16	int:H2BC8
Interaction	H3C1 interactions	ARID4B PPM1D AHCTF1 UBR4 KAT6A ASH1L CHD8 MSL1 CHD7 CBX4 XRCC1 HP1BP3 ZNF512B XIRP2 CBX6 KAT6B SPEN CUX1 AFF4	1.13e-07	901	102	19	int:H3C1
Interaction	KDM1A interactions	TNIK HAUS6 IRS4 RPGRIP1L ZSCAN5A PPM1D UBR4 CHD8 CHD7 PPP6R1 BIRC6 CIT ZNF462 PRR12 MRTFB ZNF592 ARHGAP21 CUX1	1.05e-06	941	102	18	int:KDM1A
Interaction	ZNF330 interactions	ARID4B MSL1 CHD7 XRCC1 HP1BP3 IWS1 ZNF512B UBE2O ZNF592 FAM169A CUX1 AFF4	2.66e-06	446	102	12	int:ZNF330
Interaction	PLCD3 interactions	TNIK CHD8 CXXC1 UBE2O AFF1 SPEN AFF4	2.72e-06	121	102	7	int:PLCD3
Interaction	NUP43 interactions	ARID4B AHCTF1 ASH1L CHD8 MSL1 CIT HP1BP3 IWS1 ZNF462 MRTFB ZNF592 FAM169A SPEN AHNAK2	3.17e-06	625	102	14	int:NUP43
Interaction	MEN1 interactions	PPM1D AHCTF1 UBR4 CHD8 CBX4 XRCC1 CXXC1 HP1BP3 ZNF512B ZNF462 PRR12 MRTFB ZNF592 PAK1IP1 KAT6B SPEN CUX1 AFF4	3.72e-06	1029	102	18	int:MEN1
Interaction	CBX3 interactions	BRPF3 AHCTF1 CHD8 MSL1 CHD7 XRCC1 CIT HP1BP3 ZNF512B ZNF462 UBE2O CBX6 SPEN CUX1	4.64e-06	646	102	14	int:CBX3
Interaction	CSNK2A1 interactions	CUX2 IRS4 ARID4B ZSCAN5A KAT6A CNKSR2 CBX4 XRCC1 BIRC6 CIT HP1BP3 IWS1 UBE2O ZNF592 ASXL3 PLEKHO1 KPNA1	5.79e-06	956	102	17	int:CSNK2A1
Interaction	POLR1G interactions	ARID4B UBR4 KAT6A CHD8 CHD7 XRCC1 CIT IWS1 ZNF512B ZNF592 AFF4 KPNA1	6.80e-06	489	102	12	int:POLR1G
Interaction	HMGA1 interactions	ZSCAN5A AHCTF1 PCLO KAT6A MSL1 CIT RGS3 HP1BP3 IWS1 UBE2O SPEN	8.99e-06	419	102	11	int:HMGA1
Interaction	PHF21A interactions	HAUS6 IRS4 UBR4 CHD8 CHD7 PPP6R1 BIRC6 MRTFB ZNF592 ARHGAP21	9.53e-06	343	102	10	int:PHF21A
Interaction	SMC5 interactions	ZNF777 IRS4 ARID4B SEPTIN9 AHCTF1 CHD8 MSL1 CHD7 CBX4 XRCC1 HP1BP3 ZNF512B MED19 SIMC1 SPEN CUX1 AFF4	1.04e-05	1000	102	17	int:SMC5
Interaction	PIP4K2A interactions	CHD8 RAB11FIP1 CXXC1 IWS1 UBE2O AFF1 SPEN AFF4	1.41e-05	216	102	8	int:PIP4K2A
Interaction	RPS19 interactions	ZNF777 RPGRIP1L UBR4 KAT6A ASH1L CBX4 CIT HP1BP3 UBE2O CBX6 ASXL3 PAK1IP1 KPNA1	2.04e-05	639	102	13	int:RPS19
Interaction	TLX1 interactions	ARID4B KAT6A CHD7 HP1BP3 ZNF462 PRR12 CUX1	3.05e-05	175	102	7	int:TLX1
Interaction	NAA40 interactions	TNIK HAUS6 IRS4 SEPTIN9 AHCTF1 RTN4 PPP6R1 CIT HP1BP3 ZNF512B UBE2O MRTFB FAM169A ARHGAP21 AFF4 AHNAK2	3.13e-05	978	102	16	int:NAA40
Interaction	BRPF1 interactions	BRPF3 KAT6A XRCC1 HP1BP3 KAT6B	4.74e-05	78	102	5	int:BRPF1
Interaction	CT45A5 interactions	CHD8 CXXC1 UBE2O SPEN AFF4	4.74e-05	78	102	5	int:CT45A5
Interaction	ARL16 interactions	HAUS6 AMPH RPGRIP1L BIRC6 SPEN	6.39e-05	83	102	5	int:ARL16
Interaction	CSNK2A2 interactions	BRPF3 IRS4 ARID4B ZSCAN5A KAT6A ASH1L CBX4 XRCC1 UBE2O ZNF592 SIMC1 PALM3 AHNAK2	6.76e-05	718	102	13	int:CSNK2A2
Interaction	FEV interactions	ARID4B CHD7 CXXC1 ZNF512B ZNF462 PRR12 CUX1	7.81e-05	203	102	7	int:FEV
Interaction	GBF1 interactions	HAUS6 IRS4 SEPTIN9 MFSD4A CHD8 BIRC6 MRTFB PTPRM GYPA AHNAK2	8.20e-05	442	102	10	int:GBF1
Interaction	NFKBIL1 interactions	CHD8 CHD7 CXXC1 SPEN AFF4	1.10e-04	93	102	5	int:NFKBIL1
Interaction	TERF2IP interactions	XAGE2 AHCTF1 CHD8 CHD7 XRCC1 HP1BP3 ZNF512B ZNF592 SPEN CUX1 AFF4	1.11e-04	552	102	11	int:TERF2IP
Interaction	KAT8 interactions	KAT6A MSL1 CXXC1 ZNF512B KAT6B	1.22e-04	95	102	5	int:KAT8
Interaction	SOX9 interactions	ARID4B CHD7 PRR12 SPEN CUX1	1.34e-04	97	102	5	int:SOX9
Interaction	SPAG17 interactions	CIT UBE2O PRKCSH	1.35e-04	20	102	3	int:SPAG17
Interaction	HDAC1 interactions	HAUS6 IRS4 ARID4B UBR4 CHD8 PPP6R1 BIRC6 CIT ZNF512B MRTFB ZNF592 AFF1 SPEN ARHGAP21 CUX1 KPNA1	1.36e-04	1108	102	16	int:HDAC1
Interaction	PCDHB11 interactions	DAG1 CBX4 XRCC1 CBX6	1.86e-04	56	102	4	int:PCDHB11
Interaction	SRBD1 interactions	ZNF777 KAT6A CIT CBX6 KPNA1	2.42e-04	110	102	5	int:SRBD1
Interaction	TEAD1 interactions	ARID4B CHD7 CIT ZNF462 PRR12 CUX1	2.74e-04	176	102	6	int:TEAD1
Interaction	PCDHGA5 interactions	DAG1 SNX14 CBX6 TMEM132A	2.93e-04	63	102	4	int:PCDHGA5
Interaction	AFF4 interactions	KAT6A UBE2O MED19 AFF1 AFF4	2.97e-04	115	102	5	int:AFF4
Interaction	TBXT interactions	ARID4B CHD7 PRR12 SPEN CUX1	3.09e-04	116	102	5	int:TBXT
Interaction	CAMKV interactions	TNIK ZSCAN5A AFF1 SPEN AFF4	3.35e-04	118	102	5	int:CAMKV
Interaction	CDK2AP1 interactions	ARID4B XRCC1 CIT ZNF512B KPNA1	3.35e-04	118	102	5	int:CDK2AP1
Interaction	NUP50 interactions	AHCTF1 CHD7 CIT CXXC1 ZNF512B SPEN CUX1 KPNA1	3.41e-04	341	102	8	int:NUP50
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RPGRIP1L PCLO RAB11FIP1 RGS3	7.72e-06	36	64	4	823
GeneFamily	PDZ domain containing	PCLO CNKSR2 RGS3 SHROOM4 ARHGAP21 AHNAK2	1.60e-05	152	64	6	1220
GeneFamily	PHD finger proteins	BRPF3 KAT6A ASH1L CXXC1 KAT6B	1.65e-05	90	64	5	88
GeneFamily	AF4/FMR2 family\|Super elongation complex	AFF1 AFF4	7.37e-05	4	64	2	1145
GeneFamily	Chromobox family	CBX4 CBX6	3.41e-04	8	64	2	976
GeneFamily	AF4/FMR2 family\|Super elongation complex	AFF1 AFF4	4.37e-04	9	64	2	1280
GeneFamily	CUT class homeoboxes and pseudogenes	CUX2 CUX1	4.37e-04	9	64	2	527
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	CNKSR2 DEF6 PLEKHO1 ARHGAP21 FGD3	8.08e-04	206	64	5	682
GeneFamily	Zinc fingers C2HC-type\|PHD finger proteins\|Lysine acetyltransferases	KAT6A KAT6B	1.43e-03	16	64	2	66
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	KAT6A KAT6B	1.62e-03	17	64	2	486
GeneFamily	Regulators of G-protein signaling	RGS3 RGS7	2.48e-03	21	64	2	720
GeneFamily	Sorting nexins\|PX-BAR domain containing	SNX14 SNX11	4.71e-03	29	64	2	754
Coexpression	GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_24H_DN	OGFRL1 MSL1 CBX4 DEF6 AFF1 SUCO AFF4 KPNA1	1.19e-06	200	102	8	M9925
Coexpression	NAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_DN	TNIK BRPF3 PPM1D AHCTF1 RTN4 KAT6A CHD7 CBX4 FAM169A SUCO EDRF1 AFF4	1.35e-05	680	102	12	M41089
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	KIAA0232 KAT6A CPEB3 AFF1 KAT6B SPEN SUCO EDRF1	2.32e-05	300	102	8	M8702
Coexpression	PHONG_TNF_RESPONSE_VIA_P38_COMPLETE	ARID4B PCLO CBX4 VCAN AFF1 KAT6B CUX1	2.81e-05	224	102	7	M2500
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	AMPH SEPTIN9 AHCTF1 KAT6A APBB2 RGS7 PTPRM FAM169A AFF1 KAT6B SPEN SUCO CUX1	2.81e-05	856	102	13	M4500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000	OGFRL1 PCLO MDM1 ASH1L CHD7 CIT HP1BP3 IWS1 ZNF512B ASXL3 GYPA PALM3 LTBR CFAP70 CEACAM20 AFF4 PCYT1B	3.76e-06	985	101	17	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000
CoexpressionAtlas	dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k-means-cluster#3_top-relative-expression-ranked_1000	TNIK CUX2 SGIP1 PCLO CNKSR2 CHD7 RGS7 PCYT1B	5.54e-06	202	101	8	gudmap_dev lower uro neuro_e14.5_BladdPelvicGanglion_Sox10_k3_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	OGFRL1 ARID4B MDM1 CHD7 CIT IWS1 PALM3 ARHGAP21 CUX1	1.77e-05	311	101	9	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	facebase_RNAseq_e10.5_MaxArch_2500_K3	TNIK OGFRL1 HAUS6 SGIP1 ARID4B PPM1D AHCTF1 MDM1 CNKSR2 CHD7 CIT ZNF462 UBE2O VCAN FAM169A AFF1 PLEKHO1 PCYT1B	2.30e-05	1252	101	18	facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	HAUS6 AHCTF1 PCLO RTN4 CHD7 BIRC6 CIT IWS1 MED19 FAM169A PLEKHO1	4.58e-05	532	101	11	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	OGFRL1 CUX2 IRS4 ARID4B PCLO MDM1 CHD7 CIT IWS1 FAM169A PALM3 ZFHX2 CEACAM20 ARHGAP21 CUX1	6.61e-05	989	101	15	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	OGFRL1 RPGRIP1L PPM1D MDM1 ASH1L CHD7 CIT HP1BP3 IWS1 MRTFB PALM3 CUX1 AFF4	8.32e-05	780	101	13	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#1	BRPF3 CUX2 PCLO POU6F1 ZNF462 SNX14 SNX11 SPEN	1.07e-04	306	101	8	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K1
CoexpressionAtlas	kidney_P3_CapMes_Crym_top-relative-expression-ranked_200	OGFRL1 AMPH CUX2 CNKSR2 CHD7 VCAN	1.43e-04	166	101	6	gudmap_kidney_P3_CapMes_Crym_200
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	OGFRL1 RPGRIP1L PPM1D PCLO ASH1L CHD7 CIT IWS1 MRTFB PALM3 ARHGAP21 CUX1 AFF4	1.56e-04	831	101	13	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	dev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_1000	TNIK BRPF3 SEPTIN9 DAG1 CHD7 ZNF462 MED19 VCAN SIMC1 FAM169A AFF1 SUCO ARHGAP21	1.68e-04	837	101	13	gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_1000
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5	TNIK COL15A1 SGIP1 APBB2 MFSD4A CNKSR2 STARD9 ASXL3 DEF6 PALM3 PCYT1B PCOLCE	1.72e-04	726	101	12	Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	OGFRL1 PCLO CHD8 CHD7 CIT IWS1 KAT6B CUX1	1.73e-04	328	101	8	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#2	BRPF3 PCLO KAT6A CHD7 IWS1 ZNF462	1.79e-04	173	101	6	Facebase_RNAseq_e10.5_Maxillary Arch_1000_K2
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#2_top-relative-expression-ranked_1000	PPP1R13B CHD7 MRTFB PLEKHO1	2.18e-04	62	101	4	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k2_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000	BRPF3 ARID4B PCLO MDM1 KAT6A CHD7 XRCC1 CIT IWS1 ZNF462 GYPA FAM169A PALM3 PCYT1B	2.42e-04	989	101	14	Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4	PCLO MDM1 CHD7 CIT IWS1 PALM3	3.14e-04	192	101	6	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K4
CoexpressionAtlas	dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000	CUX2 SGIP1 PCLO APBB2 CNKSR2 CHD7 RGS7	3.69e-04	278	101	7	gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k4_1000
CoexpressionAtlas	dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_500	CUX2 SGIP1 PCLO CHD7 RGS7	3.80e-04	129	101	5	gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k2_500
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	TNIK IRS4 ASH1L DAG1 CHD8 BIRC6 CIT ZNF462 STARD9 ASXL3 DCLK3 AHNAK2	4.11e-04	799	101	12	gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#5	HAUS6 PCLO CHD7 CIT IWS1 FAM169A	4.34e-04	204	101	6	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	OGFRL1 MDM1 ASH1L CIT IWS1 PALM3 AFF4	4.84e-04	291	101	7	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlas	DevelopingKidney_e15.5_Podocyte cells_emap-27915_k-means-cluster#4_top-relative-expression-ranked_1000	OGFRL1 AMPH MDM1 CHD7 ASXL3 VCAN SIMC1	5.05e-04	293	101	7	gudmap_developingKidney_e15.5_Podocyte cells_1000_k4
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ASH1L MFSD4A CHD7 BIRC6 MRTFB PTPRM PLEKHO1	3.99e-07	200	102	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D30 CIT SULT2B1 DEF6 PALM3 FGD3	3.04e-06	174	102	6	1c073177c1753e3b91ef8fd9e95230a1d13c82f3
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D30 CIT SULT2B1 DEF6 PALM3 FGD3	3.04e-06	174	102	6	5491ad5c144baf2ef9b1c58eb720c872d14feb15
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BICDL2 MFSD4A CMYA5 RAB11FIP1 ARHGAP21 AFF4	3.58e-06	179	102	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SGIP1 TBC1D30 CPEB3 MFSD4A RGS7 CFAP70	4.60e-06	187	102	6	b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	TNIK CPEB3 PPP1R13B CMYA5 TXLNB XIRP2	4.60e-06	187	102	6	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ARID4B AHCTF1 ASH1L BIRC6 SPEN SUCO	4.74e-06	188	102	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-Secretory/RAS-RAS\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BICDL2 XAGE2 MFSD4A CIT SULT2B1 PALM3	5.51e-06	193	102	6	525e0de0f25f3308daf49e7d4c8774562f1f40ad
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-Secretory/RAS\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BICDL2 XAGE2 MFSD4A CIT SULT2B1 PALM3	5.51e-06	193	102	6	2d18f39615043dfbff120a00f6540ffa93082c83
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-22\|World / Primary Cells by Cluster	CUX2 ZNF462 VCAN DCLK3 ARHGAP21 CUX1	5.51e-06	193	102	6	3b927d4b8ecb21a408424ef91a23746c21741f49
ToppCell	Club_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	BICDL2 MFSD4A ASXL3 TMEM132A PALM3	3.27e-05	159	102	5	a7bcff268b1962a561fd2848e01ae16565bce895
ToppCell	Monocytes-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	AMPH ZNF777 CPEB3 VCAN	4.38e-05	85	102	4	e73603d6f22bb56159aa5d1a2695775f038e61d8
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 CMYA5 TXLNB XIRP2 ARHGAP21	5.30e-05	176	102	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	wk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL15A1 KIAA0232 APBB2 MFSD4A CFAP70	6.22e-05	182	102	5	00a148b1e499bf16325491536d187d4dd6b70c06
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SGIP1 CPEB3 MFSD4A RGS7 CFAP70	6.38e-05	183	102	5	31ab55d5f3639f5964541d5eae23044dbda3356e
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS19 COL15A1 VCAN CFAP70 PCOLCE	6.38e-05	183	102	5	07ca2786e62eca9feecf5e54a11864a960f7641a
ToppCell	Posterior_cortex-Neuronal-Excitatory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MFSD4A CNKSR2 MRTFB SULT2B1 DCLK3	6.55e-05	184	102	5	25ccf08a8a26d7e7827b6357f33a53aaf423577d
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPH MDM1 CBX6 PALM3 CFAP70	6.55e-05	184	102	5	e7b9c69fc77040c5191ad8089697051e2589c30e
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TBC1D30 CPEB3 ZNF512B SIMC1 PALM3	6.89e-05	186	102	5	77bebf576eb9b96ecb4fefb8a82a31aaaa917fc0
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TBC1D30 CPEB3 ZNF512B SIMC1 PALM3	6.89e-05	186	102	5	13bc41c60fd628af31899a5e8b480e06cc4781be
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|368C / Donor, Lineage, Cell class and subclass (all cells)	TBC1D30 CPEB3 ZNF512B SIMC1 PALM3	7.07e-05	187	102	5	b827d9da7032bf051756ddf88352af922eb0f87b
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	TBC1D30 CPEB3 ZNF512B SIMC1 PALM3	7.07e-05	187	102	5	61c00604dda8b36a5c3eea6554e5601aa1b884f7
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	TNIK PPP1R13B CMYA5 TXLNB XIRP2	7.25e-05	188	102	5	0758b474457efa36488e0195f7357100f4b6a090
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGIP1 RAB11FIP1 RGS3 ZNF462 ZFHX2	7.43e-05	189	102	5	8e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGIP1 RAB11FIP1 RGS3 ZNF462 ZFHX2	7.43e-05	189	102	5	fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ADAMTS19 ARID4B VCAN FAM169A AFF4	8.00e-05	192	102	5	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	PRR12 SNX14 STARD9 FAM169A FGD3	8.00e-05	192	102	5	efbd52b3d2b6d3fb9ed6bc3f36aca9f4f1fcbc49
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	APBB2 MFSD4A SHROOM4 MRTFB PTPRM	8.20e-05	193	102	5	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MFSD4A SHROOM4 MRTFB PTPRM PLEKHO1	8.20e-05	193	102	5	af5108260783e69a7d67896c5bf64f862525926d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BICDL2 SEPTIN9 CMYA5 RAB11FIP1 PTPRM	8.20e-05	193	102	5	a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	ADAMTS19 ARID4B VCAN FAM169A AFF4	8.20e-05	193	102	5	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	APBB2 MFSD4A SHROOM4 MRTFB PTPRM	8.40e-05	194	102	5	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	LPS_only-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	APBB2 SHROOM4 MRTFB PTPRM PLEKHO1	8.40e-05	194	102	5	58f069efdefa0366033764446b9d6ffd4a17807e
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	APBB2 SHROOM4 MRTFB PTPRM PLEKHO1	8.40e-05	194	102	5	bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL15A1 MFSD4A RGS3 SHROOM4 PTPRM	8.61e-05	195	102	5	a432d69b0172211ee4d53675936a1dc9ce1ae1f0
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AMPH PCLO CNKSR2 RGS7 MRTFB	8.82e-05	196	102	5	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Epithelial_cells-AT1_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	APBB2 CNKSR2 RAB11FIP1 SULT2B1 PLEKHO1	8.82e-05	196	102	5	6c99d29162848161c1f166a032320f87a5d5a631
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn\|World / Primary Cells by Cluster	CUX2 ZNF462 VCAN ARHGAP21 CUX1	8.82e-05	196	102	5	9401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCell	COVID-19-Epithelial-Club,_Basal_cells\|Epithelial / Condition, Lineage and Cell class	MFSD4A CMYA5 MRTFB SULT2B1 TMEM132A	9.03e-05	197	102	5	78ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	OGFRL1 AMPH VCAN LTBR PLEKHO1	9.03e-05	197	102	5	e2c53742c7d8d1b63d93843f82330b9e20f1faa6
ToppCell	Parenchyma_Control_(B.)-Immune-TX-MoAM-4\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	CPEB3 PPP6R1 UBE2O TXLNB PLEKHO1	9.03e-05	197	102	5	dc1c55e3aacc9d60d0f111c2f20f150ca296f011
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	AMPH COL15A1 SGIP1 VCAN ABCC12	9.03e-05	197	102	5	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-myeloid_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	OGFRL1 AMPH VCAN LTBR PLEKHO1	9.03e-05	197	102	5	9838dbd1623babf8de7e9126a28fe5d3666bce42
ToppCell	PBMC\|World / Compartment, Disease Groups and Clusters	OGFRL1 SEPTIN9 RAB11FIP1 VCAN PLEKHO1	9.25e-05	198	102	5	84f5b43dad0c57556171dbc0b799735654582ecf
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AMPH PCLO CNKSR2 RGS7 MRTFB	9.25e-05	198	102	5	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	distal-Epithelial-Club-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	BICDL2 XAGE2 CIT SULT2B1 PALM3	9.25e-05	198	102	5	e56a5ffadfa4d1e34d34aec43eaf560cd80286e1
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AMPH PCLO CNKSR2 RGS7 MRTFB	9.25e-05	198	102	5	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AMPH PCLO CNKSR2 RGS7 MRTFB	9.25e-05	198	102	5	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AMPH PCLO CNKSR2 RGS7 MRTFB	9.25e-05	198	102	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-35\|World / Primary Cells by Cluster	CUX2 ARID4B RTN4 ZNF462 VCAN	9.25e-05	198	102	5	de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	APBB2 CNKSR2 RAB11FIP1 SULT2B1 PLEKHO1	9.47e-05	199	102	5	5a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCell	NS-control-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	OGFRL1 MFSD4A CMYA5 HP1BP3 MRTFB	9.47e-05	199	102	5	32bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCell	human_hepatoblastoma-Tumor_cells-T9\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	AHCTF1 CBX4 RAB11FIP1 SUCO AFF4	9.47e-05	199	102	5	e9c83555d2197b740797a9f33b64f8f7a7ba1ee2
ToppCell	distal-Epithelial-Club\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	BICDL2 XAGE2 CIT SULT2B1 PALM3	9.47e-05	199	102	5	c63ccce1285352927fd8c4f7374ec5fff8d70cec
ToppCell	control-Epithelial-Secretory\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	OGFRL1 MFSD4A CMYA5 HP1BP3 MRTFB	9.47e-05	199	102	5	262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TNIK PPP1R13B TMC3 ABCC12 CEACAM20	9.69e-05	200	102	5	7a8160e6477708f22e48c609bf8f43f3715dcb03
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	AMPH PCLO CNKSR2 RGS7 MRTFB	9.69e-05	200	102	5	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TMC3 HP1BP3 XIRP2 ABCC12	1.42e-04	115	102	4	207d464c09caf9be361daa56c83cd7da5cf9ce47
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	ARID4B TBC1D30 KIAA0232 CHD7 MRTFB KAT6B SPEN	1.81e-05	182	102	7	3887_DN
Drug	tyrphostin AG-825; Down 200; 25.2uM; MCF7; HT_HG-U133A_EA	ARID4B KIAA0232 APBB2 CHD7 KAT6B SPEN CUX1	2.01e-05	185	102	7	1114_DN
Drug	Methapyrilene hydrochloride [135-23-9]; Down 200; 13.4uM; PC3; HT_HG-U133A	TBC1D30 KAT6A APBB2 VCAN FAM169A KAT6B PLEKHO1	2.47e-05	191	102	7	6644_DN
Drug	Decamethonium bromide [541-22-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A	TNIK RPGRIP1L SEPTIN9 CPEB3 PTPRM GYPA AHNAK2	2.73e-05	194	102	7	4174_DN
Drug	Quinic acid [86-68-0]; Down 200; 19.6uM; HL60; HT_HG-U133A	COL15A1 TBC1D30 ZSCAN5A SEPTIN9 UBE2O ZNF592 VCAN	2.91e-05	196	102	7	2978_DN
Drug	Kanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; HL60; HG-U133A	TBC1D30 APBB2 CBX4 ZNF512B UBE2O SULT2B1 CUX1	3.01e-05	197	102	7	1609_UP
Drug	Thiocolchicoside [602-41-5]; Up 200; 7uM; HL60; HG-U133A	TBC1D30 MDM1 RGS3 CBX6 PAK1IP1 KAT6B CUX1	3.01e-05	197	102	7	1726_UP
Drug	Bromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; PC3; HG-U133A	SEPTIN9 ASH1L RGS3 HP1BP3 MICALL1 SULT2B1 CBX6	3.01e-05	197	102	7	1925_UP
Drug	Metformin hydrochloride [1115-70-4]; Down 200; 24.2uM; MCF7; HT_HG-U133A	TBC1D30 KAT6A APBB2 MICALL1 FAM169A PLEKHO1 AFF4	3.11e-05	198	102	7	5487_DN
Drug	Mepenzolate bromide [76-90-4]; Up 200; 9.6uM; HL60; HT_HG-U133A	RPGRIP1L SEPTIN9 PCLO UBR4 APBB2 GYPA EDRF1	3.32e-05	200	102	7	2169_UP
Disease	Intellectual Disability	CUX2 ASH1L CHD8 RGS7 ZNF462 SHROOM4 PRR12 SNX14	1.44e-04	447	100	8	C3714756
Disease	leiomyoma (is_implicated_in)	XRCC1 KAT6B	1.69e-04	6	100	2	DOID:127 (is_implicated_in)
Disease	CHARGE syndrome (implicated_via_orthology)	CHD8 CHD7	2.36e-04	7	100	2	DOID:0050834 (implicated_via_orthology)
Disease	Autistic behavior	CUX2 ZNF462	3.14e-04	8	100	2	C0856975
Disease	Facies	CHD8 AFF4	5.03e-04	10	100	2	C0282631
Disease	hematologic cancer (implicated_via_orthology)	CUX2 CUX1	8.66e-04	13	100	2	DOID:2531 (implicated_via_orthology)
Disease	fructose measurement	TNIK UBR4	8.66e-04	13	100	2	EFO_0010477
Disease	serum gamma-glutamyl transferase measurement	TNIK CUX2 SGIP1 SEPTIN9 ASH1L CIT PTPRM PALM3 AFF1 ARHGAP21	1.08e-03	914	100	10	EFO_0004532
Disease	Prostatic Neoplasms	COL15A1 KAT6A ASH1L DAG1 CHD7 XRCC1 SULT2B1 SPEN	1.19e-03	616	100	8	C0033578
Disease	Malignant neoplasm of prostate	COL15A1 KAT6A ASH1L DAG1 CHD7 XRCC1 SULT2B1 SPEN	1.19e-03	616	100	8	C0376358
Disease	Rolandic epilepsy	PTCHD3 PTPRM	1.32e-03	16	100	2	Orphanet_1945
Disease	Manic Disorder	ZNF592 STARD9 PLEKHO1	1.83e-03	71	100	3	C0024713
Disease	Malaria	GYPA LTBR	2.08e-03	20	100	2	C0024530
Disease	HbA1c measurement	TNIK CUX2 ASH1L DAG1 FAM186A GYPA PRKCSH PLEKHO1	2.12e-03	675	100	8	EFO_0004541
Disease	R-warfarin measurement	TNIK PTCHD3 RGS3 RGS7 ARHGAP21	2.12e-03	265	100	5	EFO_0803324
Disease	Manic	ZNF592 STARD9 PLEKHO1	2.39e-03	78	100	3	C0338831
Disease	Depression, Bipolar	ZNF592 STARD9 PLEKHO1	2.48e-03	79	100	3	C0005587
Disease	C-reactive protein measurement	CUX2 SGIP1 CHD7 CIT CBX6 LPA SNX11 CEACAM20 ARHGAP21 CUX1 AFF4	2.59e-03	1206	100	11	EFO_0004458
Disease	Colorectal Carcinoma	IRS4 ZSCAN5A RTN4 CNKSR2 XRCC1 SULT2B1 EDRF1 CUX1	2.69e-03	702	100	8	C0009402
Disease	unipolar depression, response to selective serotonin reuptake inhibitor	CBX4 CUX1	2.99e-03	24	100	2	EFO_0003761, EFO_0005658
Disease	alcohol consumption measurement	CUX2 SGIP1 PCLO RTN4 PPP1R13B BIRC6 CIT RGS3 MICALL1 CUX1 AFF4	3.24e-03	1242	100	11	EFO_0007878

Protein segments in the cluster

Peptide	Gene	Start	Entry
QPDSPSLPLESPEES	nan	66	Q6ZRG5
ESCSPSVELEKPPPV	ARID4B	976	Q4LE39
EAPVEIPSPSETPAK	ASH1L	1946	Q9NR48
ETPAKPSEPESTLQP	ASH1L	1956	Q9NR48
LVPPPEETAPTELSK	CHD8	66	Q9HCK8
SSVTPSPTPENEKQP	APBB2	336	Q92870
EAPETVAAEPPPIKS	BIRC6	4131	Q9NR09
PATQPTRPPTVEDKE	VCAN	1286	P13611
ITEPPSLSPDTKLEP	VCAN	2886	P13611
SDPDDTPPKLLPETV	CBX6	286	O95503
IEASKDSKPPEPSDP	CUX1	1081	P39880
QPIPKEEHPTEPSSE	CEACAM20	491	Q6UY09
SLSEQESPPEPPTLK	BRPF3	846	Q9ULD4
PTPQSPDSETEDQKP	CUX2	1256	O14529
GSENSDLDKTPPPSP	CHD7	721	Q9P2D1
SPPPFVPTLKSDDDT	CIT	371	O14578
PQPQPPSESTEKEPE	PPP1R13B	636	Q96KQ4
ISSSSPPEKEQPPRE	ASXL3	991	Q9C0F0
AIPKPTVPPSADEKS	AFF4	76	Q9UHB7
PPTEPKAEEPLAAVT	AMPH	431	P49418
PPATSSEAEQPKGEP	HP1BP3	86	Q5SSJ5
QPPEKTEESPSAPDA	PCOLCE	301	Q15113
AEDSPPSKEPSPGQE	RGS3	701	P49796
SDPLPENQSSKAPEP	ADAMTS19	901	Q8TE59
LPKPQVSDSESEEPP	IWS1	216	Q96ST2
AAVPEPSEDPTSKDP	PALM3	56	A6NDB9
APVSPNTSPGEKPED	KAT6B	1331	Q8WYB5
DQRPTPEPFPATSKE	FAM189A1	461	O60320
KEPVEETDRPSPEPS	OGFRL1	371	Q5TC84
DETSPPPEDRKEISP	RPGRIP1L	986	Q68CZ1
ETQPPEKEDASSLPP	MFSD4A	266	Q8N468
KESDLPAADPSTPIP	EDRF1	621	Q3B7T1
APSAPDLTEPKEEQP	PRKCSH	291	P14314
DLTEPKEEQPPVPSS	PRKCSH	296	P14314
KEEQPPVPSSPTEEE	PRKCSH	301	P14314
EPEPSSKPPREATLE	DCLK3	101	Q9C098
APPTEVPDRDPEKSS	DAG1	731	Q14118
ERPKTPPSNLSPIED	PCLO	1821	Q9Y6V0
ETGIPKSLSNEPPSE	PCYT1B	11	Q9Y5K3
SPSPEAELSPPAKDQ	KIAA0232	156	Q92628
PSKTQVSSLCPEPPE	FAM47B	311	Q8NA70
VASPEPEAPETPKSQ	MDM1	81	Q8TC05
PTVPEFLKTPPTADQ	MRTFB	226	Q9ULH7
PESPAKSEVQPIQPT	POU6F1	76	Q14863
ELLEPPAVPKSSSEP	MICALL1	526	Q8N3F8
PESTEKTPTADPQPS	FGD3	591	Q5JSP0
PSPCSTPPVKSLEED	PPM1D	411	O15297
PELSETSQTLPPKPF	MSL1	306	Q68DK7
EEEPESPRSSSPPIL	KAT6A	991	Q92794
TPQKEELETVAPPEP	CFAP119	256	A1A4V9
VKEPPEATATPEPLS	CXXC1	266	Q9P0U4
PSTPLSSETPKPEEN	CPEB3	36	Q8NE35
IKSQSSDTPLEGEPP	CFAP70	436	Q5T0N1
RSTPPFPEEKPLEES	CMYA5	2091	Q8N3K9
SPSDVKPLPSPDTDV	GYPA	121	P02724
KPLPSPDTDVPLSSV	GYPA	126	P02724
EPPSSLQVKPETPAS	CBX4	486	O00257
VPSTEAPSEQAPPEK	LPA	1481	P08519
TRKASSPQPSPPEEI	BICDL2	326	A1A5D9
PASTPQEDKLDPAPE	DEF6	616	Q9H4E7
ESSKPPEVDAPDKTP	FAM169A	476	Q9Y6X4
PEVDAPDKTPRIPDS	FAM169A	481	Q9Y6X4
SQTPERHKPELSPTP	HAUS6	856	Q7Z4H7
VDLPEEKLPISDSPP	AHCTF1	1501	Q8WYP5
DEKEPISITPPPSLQ	FAM186A	1041	A6NE01
EAKVEPINTPPTPSS	COL15A1	271	P39059
PKSPEPSGPLASEQD	PTCHD3	51	Q3KNS1
TPKPVPEPEKQTDHT	PTPRM	726	P28827
DPVPPETPSDSDHKK	MED19	186	A0JLT2
PSPPKAPDTNKEDDS	IRS4	756	O14654
AAVSPSKLPEDDEPP	RTN4	126	Q9NQC3
TEPEAEPESKSEPRP	RAB11FIP1	511	Q6WKZ4
PTPETKPPTEDELQQ	RGS7	246	P49802
SSPSPPPSEEKDHLE	SNX11	191	Q9Y5W9
PPSPQLSEEEEETPS	TMC3	936	Q7Z5M5
EPEPKPSLEPNTSLE	SULT2B1	326	O00204
QRKEPPDSATDPTSP	TMEM132A	876	Q24JP5
SKEPNPPIDEVISTP	KPNA1	111	P52294
KVPEVPTAPATDAAP	SEPTIN9	171	Q9UHD8
CSPSPQSETPLEKVP	SIMC1	376	Q8NDZ2
TKEPVEETQEPPESP	SHROOM4	616	Q9ULL8
TLPPRPDPTHQTSEK	STARD9	856	Q9P2P6
PEKTTSEKPPEQTPE	PRR12	1706	Q9ULL5
IDKSPPSYITQPEDP	ABCC12	416	Q96J65
AKDPPRSPPDSESEQ	PLEKHO1	336	Q53GL0
PLPKTECSTDLQPPE	AHNAK2	4821	Q8IVF2
DQAPSESPELKPLPE	AFF1	301	P51825
DSEQTPEKPPSSSAP	AFF1	436	P51825
EADTPSTPKQDSPPP	CNKSR2	691	Q8WXI2
LPPPPVDEKSERESS	XIRP2	2171	A4UGR9
DPTSENPPLPTRIEK	TNIK	641	Q9UKE5
EEKPPTKSRNPTPDQ	XAGE2	36	Q96GT9
EPEEKATPSPSPAHT	ZFHX2	1756	Q9C0A1
PQEEKQSEKPHSTPP	SPEN	2381	Q96T58
DDSPPEKATEPASPL	SNX14	301	Q9Y5W7
PTPELISKKPPDDTT	SGIP1	181	Q9BQI5
QTPSEENESPLKPPG	ZNF592	31	Q92610
ETAPDASVPPSVKPK	UBE2O	1221	Q9C0C9
TSPEPQLPKSPTDLV	ZSCAN5A	236	Q9BUG6
PEPPSAPEENKATSK	TBC1D30	846	Q9Y2I9
PSTPDTPKESPIVQL	SUCO	566	Q9UBS9
ESLPPAAEPSPVSKE	PAK1IP1	311	Q9NWT1
QPPQTTEGEKSPEPL	PPP6R1	836	Q9UPN7
SDTTCKNPLEPLPPE	LTBR	206	P36941
SEHTAPPPEEPTDKS	ZNF512B	651	Q96KM6
PPTPEETKAASPVLQ	XRCC1	451	P18887
PSPPKDDSPQLSEEL	ZNF462	1746	Q96JM2
QDSPTPVQPPEKEAS	TXLNB	36	Q8N3L3
SPEAPEKDPLTLSPT	ZNF777	131	Q9ULD5
EETISPSKEKAAPPP	UBR4	596	Q5T4S7
ESTPSEEPSPPHNSK	ARHGAP21	1496	Q5T5U3