Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

EPS8 KIFBP DCDC1 CENPF TUBGCP4 MAST2 IQGAP1 MAGI2 CCDC66 BMP10 SYNE2 DIAPH2 DIAPH3 DMD ANK2 DBNL NUMA1 PPARG PTPRT OPHN1 ARL8B P4HB NISCH SNTG1 KIF4B CEP295 TRAPPC14 DCP1A

3.84e-06109919728GO:0008092
DomainARM-type_fold

NBEAL1 LYST XPO6 DIAPH2 MMS19 DIAPH3 UBR4 VEPH1 CSE1L PKP3 MROH2B HEATR9

2.54e-0433919612IPR016024
DomainAmyloid_glyco_E2_domain

APLP1 APLP2

3.26e-0431962IPR024329
DomainA4_EXTRA

APLP1 APLP2

3.26e-0431962PS00319
DomainAmyloid_glyco_heparin-bd

APLP1 APLP2

3.26e-0431962IPR015849
DomainA4_INTRA

APLP1 APLP2

3.26e-0431962PS00320
Domain-

APLP1 APLP2

3.26e-04319623.90.570.10
DomainSox_C

SOX18 SOX7

3.26e-0431962IPR021934
DomainDrf_DAD

DIAPH2 DIAPH3

3.26e-0431962PF06345
DomainAPP_N

APLP1 APLP2

3.26e-0431962PF02177
DomainSox7/17/18_central

SOX18 SOX7

3.26e-0431962IPR033392
DomainAPP_Cu_bd

APLP1 APLP2

3.26e-0431962PF12924
DomainAPP_E2

APLP1 APLP2

3.26e-0431962PF12925
DomainAPP_amyloid

APLP1 APLP2

3.26e-0431962PF10515
DomainDrf_DAD

DIAPH2 DIAPH3

3.26e-0431962IPR010465
DomainAmyloid_glyco

APLP1 APLP2

3.26e-0431962IPR008155
DomainAmyloid_glyco_extra

APLP1 APLP2

3.26e-0431962IPR008154
Domain-

APLP1 APLP2

3.26e-04319623.30.1490.140
DomainSox17_18_mid

SOX18 SOX7

3.26e-0431962PF12067
DomainAPP_amyloid_C

APLP1 APLP2

3.26e-0431962IPR019543
DomainAmyloid_glyco_extracell_CS

APLP1 APLP2

3.26e-0431962IPR019744
DomainAmyloid_glyco_intracell_CS

APLP1 APLP2

3.26e-0431962IPR019745
DomainSOX_C

SOX18 SOX7

3.26e-0431962PS51516
DomainAmyloid_glyco_Cu-bd

APLP1 APLP2

3.26e-0431962IPR011178
DomainA4_EXTRA

APLP1 APLP2

3.26e-0431962SM00006
DomainMyb_DNA-binding

TTF1 TADA2A TERF2 MTA1

4.77e-04351964PF00249
Domain-

AKR1E2 GCLM AKR1B15

5.76e-041619633.20.20.100
DomainPH_dom-like

EPS8 NBEAL1 LYST GAB2 PLEKHH1 JAK2 PRKD2 VEPH1 TNS2 OPHN1 SNTG1 FRMPD3 DCP1A

5.85e-0442619613IPR011993
DomainLeu-rich_rpt

NLRP11 MFHAS1 TLR7 DCN LRIT3 SLITRK2 NOD1 NXF1 CPN2 NISCH

6.02e-0427119610IPR001611
Domain-

GTF2IRD2 GTF2IRD2B

6.48e-04419623.90.1460.10
DomainGTF2I

GTF2IRD2 GTF2IRD2B

6.48e-0441962PS51139
DomainGTF2I

GTF2IRD2 GTF2IRD2B

6.48e-0441962PF02946
DomainGTF2I

GTF2IRD2 GTF2IRD2B

6.48e-0441962IPR004212
DomainMYB_LIKE

TTF1 TADA2A TERF2 MTA1

6.57e-04381964PS50090
DomainNADP_OxRdtase_dom

AKR1E2 GCLM AKR1B15

6.94e-04171963IPR023210
DomainAldo_ket_red

AKR1E2 GCLM AKR1B15

6.94e-04171963PF00248
DomainLRR

MFHAS1 TLR7 DCN LRIT3 SLITRK2 NXF1 CPN2 NISCH

1.31e-032011968PS51450
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

ABCC3 LPCAT1 SQLE UTP14A RBM26 RPS18 NOD1 DBF4 TADA2A DIAPH3 EXOC3L2 MTO1 NXF1 UBR4 RALGAPB APLP2 PPHLN1 UFL1 USP16 TRMT2A SLC12A4 P4HB TRIM56 RBM5 LSS NDUFAF6 MAML2 MAPK6 R3HDM1 ABHD11

1.83e-1013272013032694731
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

INTU CENPF UTP14A ZBTB41 LYST DNTTIP2 IQGAP1 SYNE2 GTF2IRD2 DIAPH3 DMD HSPA6 BAHCC1 SLC25A18 ANK2 PCDHGB7 UBR4 DBNL NUMA1 TERF2 GTF2IRD2B SLC12A4 ARL8B P4HB TNN ANKRD30A RBM5 CEP295 MAPK6 ATP2A3

1.29e-0914422013035575683
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

INTU FAM91A1 TENM2 PLEKHH1 ZCCHC14 MAGI2 SEMA6D ZNF644 FRAS1 ANKFY1 RALGAPB NISCH R3HDM1 CEP170B

1.27e-074072011412693553
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

EPS8 CLK4 UTP14A RBM26 FAM91A1 TTF1 IQGAP1 TMEM266 HSPA6 NXF1 PIGK DBNL RALGAPB NTPCR APLP2 PPHLN1 UFL1 TERF2 CASK MTA1 P4HB TRIM56 BRD9 HELZ2 RBM5 DDX20 CEP170B

1.72e-0714972012731527615
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

INTU KIFBP NBPF12 PLEKHH1 ZNF644 ANKFY1 RALGAPB

2.40e-06103201710574462
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

KIFBP UTP14A RBM26 HRNR TTF1 ZNF644 CCDC15 MMS19 PRPF39 UBR4 UFL1 DEPDC1 PPARG MTA1 TRMT2A ARL8B NISCH DCP1A

2.84e-068572011825609649
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CENPF UTP14A TTF1 DNTTIP2 IQGAP1 SYNE2 NXF1 SEC23B UBR4 NUMA1 RBM28 CSE1L P4HB HELZ2 DDX20

6.90e-066532011522586326
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

NBPF12 HRNR SYNE2 ANGPTL3 UBR4 NBPF1 ANKRD30A SNTG1

7.12e-06170201823314748
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

LPCAT1 UTP14A RBM26 FAM91A1 RPS18 DNTTIP2 IQGAP1 GCLM SYNE2 DIAPH3 METAP2 HSPA6 SEC23B UBR4 NTPCR NUMA1 UFL1 DNAJC17 CSE1L P4HB PKP3 UBA6 DDX20

8.41e-0614152012328515276
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

EPS8 LPCAT1 TATDN2 ZNF280B DCN SOWAHC POMP DBF4 TADA2A TRAPPC11 NUMA1 PPHLN1 RBM5 DDX20 DCP1A

9.34e-066702011522990118
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

GGA2 UTP14A RBM26 FAM91A1 RPS18 SOWAHC STAT2 GAB2 NEK4 DBF4 DIAPH3 DMD METAP2 SEC23B PRKD2 PKP3 LSS R3HDM1 DCP1A

1.06e-0510382011926673895
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TATDN2 FAM91A1 IQGAP1 XPO6 DBF4 ZNF644 RALGAPB NUMA1 UFL1 TERF2 USP16 MTA1 PKP3 HELZ2 DDX20 DCP1A

1.26e-057742011615302935
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

RBM12B UTP14A RBM26 RPS18 DNTTIP2 RARS2 MTO1 NXF1 NTPCR PPHLN1 RBM28 P4HB TRIM56 HELZ2 RBM5 R3HDM1

2.09e-058072011622681889
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

TET2 KIFBP SOWAHC SOX7 SYNE2 NXF1 BAHCC1 ZFPM2 BRD9 LSS DDX20

2.27e-053982011135016035
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ABCC3 LPCAT1 DCN PLEKHH1 NEK4 SYNE2 TRAPPC11 FAT4 ANKFY1 PIGK UBR4 NTPCR CEP295 DNAH11

2.33e-056382011431182584
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ABCC3 MFHAS1 MAST2 LYST JAK2 ZCCHC14 XPO6 DIAPH2 BAHCC1 PRKD2 NDST1 FRAS1 UBR4 NBPF1 SLC12A4 NISCH HELZ2 ATP2A3 CEP170B

2.51e-0511052011935748872
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

INTU LPCAT1 DCDC1 MAST2 SOWAHC DNTTIP2 RARS2 MMS19 TADA2A MTO1 BAHCC1 PRKD2 NTPCR MTA1 TRMT2A TRIM56 BRD9 CEP295 CEP170B

2.87e-0511162011931753913
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

INTU KIFBP SDCCAG8 TUBGCP4 GAB2 IQGAP1 NEK4 POMP XPO6 NTPCR APLP2 EXOC5 CSE1L ARL8B P4HB NISCH TRIM56 TTC21B PDE5A DDX20 DCP1A

2.94e-0513212012127173435
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

LPCAT1 SQLE RPS18 TUBGCP4 RARS2 MMS19 PIGK UBR4 APLP2 EXOC5 CSE1L P4HB RBM5 DDX20

3.20e-056572011436180527
Pubmed

Protein kinase D2 contributes to either IL-2 promoter regulation or induction of cell death upon TCR stimulation depending on its activity in Jurkat cells.

PRKD2 IL2

3.32e-052201217077180
Pubmed

Clonal analysis of TET2 and JAK2 mutations suggests that TET2 can be a late event in the progression of myeloproliferative neoplasms.

TET2 JAK2

3.32e-052201220061559
Pubmed

Structural aspects and physiological consequences of APP/APLP trans-dimerization.

APLP1 APLP2

3.32e-052201221952790
Pubmed

Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal.

TET2 JAK2

3.32e-052201229991556
Pubmed

Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms.

TET2 JAK2

3.32e-052201225281607
Pubmed

Detailed mapping, mutation analysis, and intragenic polymorphism identification in candidate Noonan syndrome genes MYL2, DCN, EPS8, and RPL6.

EPS8 DCN

3.32e-052201211185075
Pubmed

Sildenafil reduces respiratory muscle weakness and fibrosis in the mdx mouse model of Duchenne muscular dystrophy.

DMD PDE5A

3.32e-052201222653783
Pubmed

[Relationship between TET2 Gene SNP rs3733609 C/T and JAK2V617F Allele Burden in Patients with Myeloproliferative Neoplasms].

TET2 JAK2

3.32e-052201231607314
Pubmed

Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling.

STAT2 UBR4

3.32e-052201223555265
Pubmed

Mutation rates in the dystrophin gene: a hotspot of mutation at a CpG dinucleotide.

F9 DMD

3.32e-052201215643612
Pubmed

Mutations of JAK2 and TET2, but not CBL are detectable in a high portion of patients with refractory anemia with ring sideroblasts and thrombocytosis.

TET2 JAK2

3.32e-052201219903679
Pubmed

The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation.

APLP1 APLP2

3.32e-052201214970212
Pubmed

Ankyrin-B is required for intracellular sorting of structurally diverse Ca2+ homeostasis proteins.

ANK2 ATP2A3

3.32e-052201210579720
Pubmed

Amyloid-precursor Like Proteins APLP1 and APLP2 Are Dispensable for Normal Development of the Neonatal Respiratory Network.

APLP1 APLP2

3.32e-052201228690498
Pubmed

TET-mediated hydroxymethylcytosine at the Pparγ locus is required for initiation of adipogenic differentiation.

TET2 PPARG

3.32e-052201228100914
Pubmed

7-ketocholesteryl-9-carboxynonanoate enhances ATP binding cassette transporter A1 expression mediated by PPARγ in THP-1 macrophages.

ABCA1 PPARG

3.32e-052201224814410
Pubmed

CDEBP, a site-specific DNA-binding protein of the 'APP-like' family, is required during the early development of the mouse.

APLP1 APLP2

3.32e-05220127539437
Pubmed

The role of the JAK2 GGCC haplotype and the TET2 gene in familial myeloproliferative neoplasms.

TET2 JAK2

3.32e-052201221173100
Pubmed

Mutation in TET2 in myeloid cancers.

TET2 JAK2

3.32e-052201219474426
Pubmed

A novel compound 4010B-30 upregulates apolipoprotein A-I gene expression through activation of PPARγ in HepG2 cells.

ABCA1 PPARG

3.32e-052201225734982
Pubmed

Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.

GTF2IRD2 GTF2IRD2B

3.32e-052201215388857
Pubmed

Chromosomal abnormalities in transformed Ph-negative myeloproliferative neoplasms are associated to the transformation subtype and independent of JAK2 and the TET2 mutations.

TET2 JAK2

3.32e-052201220629097
Pubmed

Effect of mutation order on myeloproliferative neoplasms.

TET2 JAK2

3.32e-052201225671252
Pubmed

Extent of hematopoietic involvement by TET2 mutations in JAK2V⁶¹⁷F polycythemia vera.

TET2 JAK2

3.32e-052201221273266
Pubmed

Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells.

LPCAT1 SFTPC

3.32e-052201216864775
Pubmed

Accumulation of the amyloid precursor-like protein APLP2 and reduction of APLP1 in retinoic acid-differentiated human neuroblastoma cells upon curcumin-induced neurite retraction.

APLP1 APLP2

3.32e-052201214597230
Pubmed

Redox-regulated peptide transfer from the transporter associated with antigen processing to major histocompatibility complex class I molecules by protein disulfide isomerase.

NXF1 P4HB

3.32e-052201221299467
Pubmed

Quercetin increases macrophage cholesterol efflux to inhibit foam cell formation through activating PPARγ-ABCA1 pathway.

ABCA1 PPARG

3.32e-052201226617799
Pubmed

MTA1 promotes viability and motility in nasopharyngeal carcinoma by modulating IQGAP1 expression.

IQGAP1 MTA1

3.32e-052201229125886
Pubmed

The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1.

HSPA6 HSPA7

3.32e-05220121346391
Pubmed

Downregulation of Jumonji-C domain-containing protein 5 inhibits proliferation by silibinin in the oral cancer PDTX model.

MTA1 KDM8

3.32e-052201232678829
Pubmed

Functions of the APP gene family in the nervous system: insights from mouse models.

APLP1 APLP2

3.32e-052201221931985
Pubmed

The amyloid beta-protein precursor and its mammalian homologues. Evidence for a zinc-modulated heparin-binding superfamily.

APLP1 APLP2

3.32e-05220127929392
Pubmed

Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans.

JAK2 PTPRT

3.32e-052201231844068
Pubmed

Significance of JAK2 and TET2 mutations in myelodysplastic syndromes.

TET2 JAK2

3.32e-052201220171768
Pubmed

Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription.

APLP1 APLP2

3.32e-052201212228233
Pubmed

Genetic variants of SDCCAG8 and MAGI2 in mitosis-related pathway genes are independent predictors of cutaneous melanoma-specific survival.

SDCCAG8 MAGI2

3.32e-052201234375487
Pubmed

Optimizing detection of RET and PPARg rearrangements in thyroid neoplastic cells using a home-brew tetracolor probe.

RET PPARG

3.32e-052201224510380
Pubmed

ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms.

TET2 ABCA1

3.32e-052201232160545
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TET2 KDM5B CENPF ZNF644 TADA2A DIAPH3 HSPA6 NXF1 ANKFY1 UBR4 DCP1A

3.54e-054182011134709266
Pubmed

Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling.

EPS8 ITGB2 TNS2

4.03e-0512201312606711
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TET2 KDM5B MAST2 LYST GAB2 NEK4 ZCCHC14 FSIP2 SYNE2 SEC23B DBNL RALGAPB TRAPPC14 R3HDM1 CEP170B DCP1A

4.53e-058612011636931259
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

RARS2 HSPA7 NXF1 NDST1 EXOC5 CSE1L TRMT2A P4HB ATP2A3

4.59e-05285201932838362
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

NBPF12 RPS18 HRNR NEK4 HSPA6 FAT4 FRAS1 ANKFY1 NBPF1 P4HB TTC21B ATP2A3

4.90e-055132011225798074
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KIFBP CENPF TENM2 IQGAP1 MAGI2 SYNE2 DIAPH2 ANKFY1 ANK2 UBR4 NUMA1 CASK NISCH UBA6 KIF4B FRMPD3 CEP170B

4.93e-059632011728671696
Pubmed

The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn.

RET CCK EMX1

5.21e-0513201328041852
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

KIFBP CENPF RPS18 IQGAP1 PRPF39 NXF1 SEC23B PRKD2 TRAPPC11 PIGK UBR4 NTPCR NUMA1 ATP2A3

6.71e-057042011429955894
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

CENPF HRNR PLEKHH1 DMD SEC23B ANKFY1 UBR4 TNS2 LSS

7.53e-05304201932235678
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

RBM26 TTF1 FSIP2 SYNE2 DNAH9 DBNL

8.38e-05123201626912792
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

KIFBP CENPF UTP14A RBM26 RPS18 MAST2 DNTTIP2 IQGAP1 NXF1 PRKD2 ANKFY1 UBR4 DBNL NUMA1 APLP2 UFL1 CSE1L P4HB UBA6 RBM5 DDX20

8.65e-0514252012130948266
Pubmed

Human transcription factor protein interaction networks.

TET2 UTP14A HRNR STAT2 ZNF644 SYNE2 TADA2A NXF1 SEC23B UBR4 NUMA1 RBM28 PPARG ZFPM2 MTA1 CSE1L P4HB TTC31 BRD9 R3HDM1 DCP1A

8.99e-0514292012135140242
Pubmed

FABP4 activates the JAK2/STAT2 pathway via Rap1a in the homocysteine-induced macrophage inflammatory response in ApoE-/- mice atherosclerosis.

STAT2 JAK2

9.93e-053201234725437
Pubmed

Association of torsades de pointes with novel and known single nucleotide polymorphisms in long QT syndrome genes.

KCNQ1 ANK2

9.93e-053201217161064
Pubmed

Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function.

ITGB2 IL2

9.93e-053201219234188
Pubmed

Protein tyrosine phosphatase receptor type γ is a JAK phosphatase and negatively regulates leukocyte integrin activation.

ITGB2 JAK2

9.93e-053201225624455
Pubmed

Ankyrin B and Ankyrin B variants differentially modulate intracellular and surface Cav2.1 levels.

ANK2 EMX1

9.93e-053201231477143
Pubmed

Increased IRF9-STAT2 Signaling Leads to Adaptive Resistance toward Targeted Therapy in Melanoma by Restraining GSDME-Dependent Pyroptosis.

STAT2 GSDME

9.93e-053201235148998
Pubmed

Semaphorin 6D reverse signaling controls macrophage lipid metabolism and anti-inflammatory polarization.

SEMA6D PPARG

9.93e-053201229777213
Pubmed

Tumor formation via loss of a molecular motor protein.

ABCC3 KIF4B

9.93e-053201216890532
Pubmed

Epigenetic disruption of miR-130a promotes prostate cancer by targeting SEC23B and DEPDC1.

SEC23B DEPDC1

9.93e-053201227984115
Pubmed

Gene silencing analyses against amyloid precursor protein (APP) gene family by RNA interference.

APLP1 APLP2

9.93e-053201216889988
Pubmed

Interaction between Calpain 5, Peroxisome proliferator-activated receptor-gamma and Peroxisome proliferator-activated receptor-delta genes: a polygenic approach to obesity.

CAPN5 PPARG

9.93e-053201218657264
Pubmed

Association of variants in PPARγ², IGF2BP2, and KCNQ1 with a susceptibility to gestational diabetes mellitus in a Korean population.

KCNQ1 PPARG

9.93e-053201223364967
Pubmed

Identifying C1QB, ITGAM, and ITGB2 as potential diagnostic candidate genes for diabetic nephropathy using bioinformatics analysis.

ITGB2 KCNQ1

9.93e-053201237250717
Pubmed

Complement receptor 3 influences toll-like receptor 7/8-dependent inflammation: implications for autoimmune diseases characterized by antibody reactivity to ribonucleoproteins.

TLR7 ITGB2

9.93e-053201223386618
Pubmed

A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects.

LRIT3 GRK1

9.93e-053201226427409
Pubmed

Amyloid precursor proteins are constituents of the presynaptic active zone.

APLP1 APLP2

9.93e-053201223815291
Pubmed

APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival.

APLP1 APLP2

9.93e-053201232891188
Pubmed

Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.

GTF2IRD2 GTF2IRD2B

9.93e-053201215100712
Pubmed

JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation.

ITGB2 JAK2

9.93e-053201230024857
Pubmed

APLP2 regulates neuronal stem cell differentiation during cortical development.

APLP1 APLP2

9.93e-053201223345401
Pubmed

[The Expression of Genes Encoding ABCA1 and ABCG1 Transporters and PPARγ, LXRβ, and RORα Transcriptional Factors in Subcutaneous and Visceral Adipose Tissue in Women with Metabolic Syndrome].

ABCA1 PPARG

9.93e-053201233566026
Pubmed

Cell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval development.

EPS8 CASK

9.93e-053201216688213
Pubmed

Role of Toll-like receptors in the pathogenesis of dystrophin-deficient skeletal and heart muscle.

TLR7 DMD

9.93e-053201224368419
Pubmed

MetAP2 inhibition reduces food intake and body weight in a ciliopathy mouse model of obesity.

METAP2 TTC21B

9.93e-053201231877115
Pubmed

JAK2/STAT2/STAT3 are required for myogenic differentiation.

STAT2 JAK2

9.93e-053201218835816
Pubmed

Essential and nonredundant roles for Diaphanous formins in cortical microtubule capture and directed cell migration.

DIAPH2 DIAPH3

9.93e-053201224403606
Pubmed

Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members.

APLP1 APLP2

9.93e-053201211050115
Pubmed

Survey of 548 oncogenic fusion transcripts in thyroid tumors supports the importance of the already established thyroid fusions genes.

RET PPARG

9.93e-053201222961909
Pubmed

Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure.

TET2 JAK2

9.93e-053201234210413
Pubmed

Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma.

PPARG HELZ2

9.93e-053201216239304
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

TTF1 TADA2A TERF2 MTA1

6.38e-04531344532
GeneFamilyAdenosine deaminase family

ADA2 AMPD3

8.02e-04613421302
GeneFamilyPDZ domain containing

INTU MAST2 MAGI2 CASK SNTG1 FRMPD3

9.49e-0415213461220
GeneFamilyExportins

XPO6 CSE1L

1.12e-0371342547
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEAL1 LYST

1.90e-03913421230
CoexpressionGSE17721_0.5H_VS_24H_CPG_BMDC_DN

ABCC3 ABCA1 ME1 LYST JAK2 GCLM AMPD3 RNF135 RBM28 AKR1B15

3.57e-0620020110M4129
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

LPCAT1 SWT1 CENPF RBM26 TLR7 SOWAHC TTF1 DNTTIP2 CCDC66 XPO6 DBF4 ZNF644 SYNE2 DIAPH2 DMD PRPF39 ANK2 VEPH1 PPHLN1 UFL1 DEPDC1 USP16 EXOC5 CSE1L UBA6 LSS CEP295 MAPK6 TRAPPC14 R3HDM1

2.24e-06125719930facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

INTU LPCAT1 SWT1 CENPF SQLE ZBTB41 MAST2 SOWAHC GAB2 CCDC66 ZNF644 SYNE2 TRAPPC11 ANKFY1 NUMA1 OPHN1 BRD9 RBM5 LSS TRAPPC14 R3HDM1

1.48e-0578019921Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

LPCAT1 SWT1 CENPF RBM26 TLR7 SOWAHC TTF1 DNTTIP2 CCDC66 XPO6 DBF4 ZNF644 SYNE2 DIAPH2 DMD PRPF39 ANK2 VEPH1 PPHLN1 UFL1 DEPDC1 USP16 EXOC5 CSE1L UBA6 LSS CEP295 MAPK6 TRAPPC14 R3HDM1 ATP2A3

1.56e-05145919931facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#1_top-relative-expression-ranked_1000

LPCAT1 RBM26 GSDME NDST1 APLP1 CASK NISCH RBM5

2.25e-051241998gudmap_developingGonad_e16.5_epididymis_1000_k1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

LPCAT1 SWT1 CENPF UTP14A ZBTB41 MAST2 SOWAHC NEK4 CCDC66 DBF4 SYNE2 CCDC15 DMD TRAPPC11 NUMA1 APLP1 RFX4 BRD9 RBM5 CEP295 TRAPPC14

3.74e-0583119921Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
ToppCell10x5'v1-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SOX18 SOX7 CA4 GPR4 FAT4 NAALAD2 TNS2 PPARG TNN

2.58e-071942019e141beafc9252e5d8c949252bfab53e127c881dc
ToppCell10x5'v1-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SOX18 SOX7 CA4 GPR4 FAT4 NAALAD2 TNS2 PPARG TNN

2.58e-071942019953578102ffc7b612ee8fce45e414750800fef5d
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RBM12B TTF1 GCLM ZSWIM4 RET HEATR9 DDX20 DCP1A

1.41e-06176201891ad2c34144f72283ca112fd3b3784f2f6259f65
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC1 MFHAS1 EVC MAGI2 SYNE2 DIAPH3 FRAS1 DNAH11

2.13e-061862018f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 RBM26 TENM2 ANK2 APLP1 NISCH PDE5A ATP2A3

2.31e-061882018a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellfacs-BAT-Fat-3m-Endothelial-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX18 SOX7 ITPRIPL1 CA4 GPR4 TNS2 APLP2 PPARG

2.81e-061932018e340064cd146deac03f2d0fd43e2e218bb6057c9
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SQLE SEC23B ANK2 UBR4 APLP1 NISCH ATP2A3 CEP170B

2.81e-061932018fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCellfacs-BAT-Fat-3m-Endothelial-endothelial_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX18 SOX7 ITPRIPL1 CA4 GPR4 TNS2 APLP2 PPARG

2.81e-061932018a211b386fd0fb9da9937361d29d90925a72c9715
ToppCellfacs-BAT-Fat-3m-Endothelial|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX18 SOX7 ITPRIPL1 CA4 GPR4 TNS2 APLP2 PPARG

2.81e-0619320183086c33f4d6fab66966818737f95ae4d6b2615b0
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INTU DCDC1 SYNE2 DMD DNAH9 WDR49 PTPRT DNAH11

3.27e-06197201874a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCelldroplet-Heart-nan-18m-Hematologic-erythrocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LVRN GCLM DIAPH3 DCAF12 VEPH1 TRIM10

7.78e-061042016060f0baca239ab89c18be40c1aa31931f4791b62
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZCCHC14 FSIP2 HSPA6 BAHCC1 NDST1 DHRS12 TRAPPC14

1.02e-051652017242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZCCHC14 FSIP2 HSPA6 BAHCC1 NDST1 DHRS12 TRAPPC14

1.02e-051652017436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LVRN TENM2 TMEM266 FRAS1 ZFPM2 SNTG1 LSS

1.11e-0516720171adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LVRN TENM2 TMEM266 FRAS1 ZFPM2 SNTG1 LSS

1.11e-051672017743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ABCA1 DCN TADA2A ANKFY1 PPARG MAML2 CEP170B

1.20e-051692017665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ABCA1 DCN TADA2A ANKFY1 PPARG MAML2 CEP170B

1.20e-0516920176614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 TERF2 USP16 PTPRT SNTG1 PDE5A ATP2A3

1.45e-051742017f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DCN DMD FAT4 UBL4B ZFPM2 PDE5A MAML2

1.50e-0517520171799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LPCAT1 CENPF ME1 DBF4 DIAPH3 SFTPC DEPDC1

1.61e-0517720173081ce5fc66a1bb833719d6c0e0a6fc7115eeb91
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-1|TCGA-Liver / Sample_Type by Project: Shred V9

FAXC IQGAP1 ZSWIM4 FRAS1 VEPH1 PDE5A MAML2

1.67e-05178201751c59dabf2d7aef1b1964f6f766d5ec07ef90f5a
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INTU CENPF SOWAHC ME1 DBF4 DIAPH3 DEPDC1

1.80e-05180201743fd5c498a87bb078d101298b472656f3294686a
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TENM2 MAGI2 SEMA6D SH3RF2 DIAPH2 CCK R3HDM1

1.86e-05181201757994ff4ecffb15653aee00644d9f887f5e3461d
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPF RPS18 DCN DBF4 SYNE2 DIAPH3 CEP295

2.22e-05186201715ab6666748a641226e42e6ca6eeaf186a501c95
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPF RPS18 DCN DBF4 SYNE2 DIAPH3 CEP295

2.22e-0518620174ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC1 EVC MAGI2 SYNE2 DIAPH3 MAML2 DNAH11

2.46e-051892017904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellMS-CD8-antiviral_CD4|MS / Condition, Cell_class and T cell subcluster

KIFBP GCLM ITPRIPL1 TERF2 MTA1 DDX20 MAML2

2.55e-0519020178c831c4560b8e70f92b4c15644fea39f7f7afcf2
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-immature_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SOX18 SOX7 SH3RF2 GPR4 PPARG ZFPM2 TNN

2.72e-0519220175af3b2b38495e925497c48f605d618bbf970965d
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-1|TCGA-Endometrium / Sample_Type by Project: Shred V9

KIFBP TUBGCP4 DIAPH3 FRAS1 GDE1 MAPK6 R3HDM1

2.81e-051932017c2673d86f7d7b849788036032a93a6d136a70040
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SQLE SEC23B ANK2 UBR4 NISCH ATP2A3 CEP170B

2.81e-051932017471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 DCDC1 MFHAS1 EVC SYNE2 DIAPH3 MAML2

2.91e-051942017e577d9e88390b36b5a09b97fe1026089892275a3
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC23B ANK2 UBR4 APLP1 NISCH ATP2A3 CEP170B

2.91e-0519420170b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell10x5'v1-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SOX18 CA4 GPR4 NAALAD2 TNS2 PPARG TNN

3.01e-05195201722a481927147ec4ae9d59e6af7c87df0e9cb51e4
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

EPS8 DCN GAB2 DIAPH2 ZFPM2 OPHN1 MAML2

3.01e-0519520176a02ebbeb3199447ddce64d92d8809436e040eba
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 IQGAP1 APLP1 RET NISCH PDE5A ATP2A3

3.01e-0519520173e519cffa6144a62b06124642a14c9ff39b76554
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DCN MAGI2 FAT4 NAALAD2 ZFPM2 PDE5A MAML2

3.11e-051962017dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI2 DIAPH2 DMD VEPH1 OPHN1 CASK MAML2

3.11e-051962017ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RPS18 DCN MAGI2 NAALAD2 ZFPM2 PDE5A MAML2

3.11e-05196201722538376a95fe3afe8639a216a5497087aa94110
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial-Astrocyte|GW19 / Sample Type, Dataset, Time_group, and Cell type.

LPCAT1 ME1 SLITRK2 SLC25A18 VEPH1 SLC12A4 HES5

3.31e-051982017bfad1c51cf884ff7ce89f8278820800582541dc7
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DCDC1 CENPF DNAH9 WDR49 DEPDC1 CCK DNAH11

3.31e-051982017f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

LPCAT1 ME1 SLITRK2 SLC25A18 VEPH1 SLC12A4 HES5

3.31e-0519820176372e65242236c497d9b3be147092897c1609d22
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NBEAL1 ME1 SH3RF2 SYNE2 FRAS1 VEPH1 PKP3

3.31e-051982017b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

GAB2 MAGI2 DIAPH2 DMD OPHN1 CASK MAML2

3.31e-0519820171996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellCOVID-19_Convalescent-PLT_3|World / Disease Group and Platelet Clusters

GTF2IRD2 PYGM DMD DHRS12 LSS QTRT1

3.73e-051372016bb54bb81b450462ad521b57e1a07a80ce1678e67
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SOX18 TRIM6 SOX7 KCNQ1 PKP3 HELZ2

4.93e-0514420161c118b22c2ff3a526a5207d6c9d772636ee065fd
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

INTU CENPF WDR49 NAALAD2 CEP295 DNAH11

7.96e-051572016410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPF AKR1E2 DBF4 DIAPH3 DEPDC1 ULK3

8.24e-051582016ee8ce3cd202807df692b28bb1a81827d49d73862
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

TENM2 DMD DNAH9 PTPRT ZFPM2 SNTG1

8.54e-0515920165335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM2 MAGI2 SLITRK2 TMEM266 ZFP28 ZFPM2

8.54e-051592016fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM2 MAGI2 SLITRK2 TMEM266 ZFP28 ZFPM2

8.54e-051592016aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TENM2 MAGI2 SLITRK2 TMEM266 ZFP28 ZFPM2

8.54e-0515920168bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK|Entopeduncular / BrainAtlas - Mouse McCarroll V32

SOX18 TRIM6 SOX7 KCNQ1 ITPRIPL1 GPR4

8.84e-05160201604714d0b9bad4c11fa193ed168e2d84a4df39e2e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCN TENM2 MAGI2 SLITRK2 TMEM266 WDR49

1.15e-041682016fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

POU6F2 DCDC1 EVC MAGI2 SYNE2 FRAS1

1.15e-041682016a086c306be430adf0632ba53e98cd8014d2de330
ToppCelldroplet-Heart-nan-18m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LVRN TRIM6 SOX7 CA4 ZFP28 KDM8

1.15e-0416820162201ae834b53cbdc085f8f02607fa5b5bd911268
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INTU DCDC1 DNAH9 WDR49 PTPRT DNAH11

1.19e-04169201614aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCN DNAH9 FRAS1 VEPH1 PTPRT DNAH11

1.19e-04169201612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MAGEA12 PAPOLB EVC DCN CA4 GPR4

1.27e-041712016a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SDCCAG8 TRAPPC11 PCDHGB7 OPHN1 TRAPPC14 HES5

1.27e-0417120169be3554626408bb897d1f1c43b3ab4a92651f2e2
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SDCCAG8 TRAPPC11 PCDHGB7 OPHN1 TRAPPC14 HES5

1.27e-0417120166a2f88c2a62cb2f69797804e24eb1137a3e148de
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Thalamus / BrainAtlas - Mouse McCarroll V32

SOX18 SOX7 FKBP6 PKP3 HELZ2

1.36e-0410920154e4a884b8979f4ff8b232c1581ea78884dda29ed
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CENPF DBF4 SYNE2 DIAPH3 DEPDC1 HEATR9

1.40e-041742016b43fb0fbb492c1be6e791a1c4d6c4e5956955ee4
ToppCellTCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue-Breast_normal_tissue|TCGA-Breast / Sample_Type by Project: Shred V9

LVRN DMD ITPRIPL1 CA4 NAALAD2 PPARG

1.40e-0417420160f3ec0d0d4344e10c9b48adc9174123f6402dc51
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CENPF DBF4 SYNE2 DIAPH3 DEPDC1 HEATR9

1.40e-04174201694575a605c725de83f66a6cf7df9d7bb360ffc56
ToppCellTCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue-Breast_normal_tissue-3|TCGA-Breast / Sample_Type by Project: Shred V9

LVRN DMD ITPRIPL1 CA4 NAALAD2 PPARG

1.40e-0417420167f8f5fafae08676d2b90cab9802c3c9320f1370e
ToppCellTCGA-Breast-Solid_Tissue_Normal|TCGA-Breast / Sample_Type by Project: Shred V9

LVRN DMD ITPRIPL1 CA4 NAALAD2 PPARG

1.40e-041742016e2f240d60bffbe8e6d60f0bb405b231bd3c96875
ToppCellBAL-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CENPF DBF4 SYNE2 DIAPH3 DEPDC1 HEATR9

1.40e-04174201640c81ab36d7931e271e20d7d56fed32463c75f41
ToppCellTCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue|TCGA-Breast / Sample_Type by Project: Shred V9

LVRN DMD ITPRIPL1 CA4 NAALAD2 PPARG

1.40e-0417420161aadbf2642b6d1320ceabd92e6ff59e11f16c315
ToppCellClub-club-15|World / Class top

CENPF CCDC66 DBF4 DIAPH3 BRD9 KDM8

1.44e-041752016ca9d012f520f697c7450ec6958a015e20538a6a8
ToppCellCOVID-19_Mild-Neu_3|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

NBEAL1 SQLE ANKFY1 RBM28 CASK FRMPD3

1.49e-0417620162049767fd591045cfcf5b1071d80798e52843f27
ToppCellwk_20-22-Hematologic-Meg-ery-Cycling_definitive_erythroblast|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CENPF GCLM CA4 DCAF12 DEPDC1 TRIM10

1.49e-04176201698814f0a67411b2f7b25dc489b2aadb77f45a853
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCDC1 SH3RF2 DIAPH2 CA4 ZFPM2 R3HDM1

1.49e-041762016c7be4eaa5eb76ad9389fb9d15ad0934e88d267d1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EVC MAGI2 DIAPH3 PTPRT MAML2 DNAH11

1.49e-041762016327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CENPF SOX18 SOX7 DIAPH3 EXOC3L2 DEPDC1

1.58e-041782016ea10117026021c959ffc871fc377cdb3e161d264
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

INTU EVC MAGI2 PTPRT OPHN1 DNAH11

1.58e-041782016c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NKX2-3 SOX18 SOX7 CA4 PPARG TRIM10

1.58e-041782016a3f95f0002f408b5b6c57e28b297b5b2737e919c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

POU6F2 TENM2 MAGI2 TMEM266 WDR49 ZFPM2

1.63e-0417920167394e77e665bf16d3733df91bb12907be460ab44
ToppCellfacs-Marrow-T_cells-18m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INTU KIFBP PRPF39 LSS NDUFAF6 ABHD11

1.73e-041812016064057ab36c6d92c36572b73142b42d201709d7b
ToppCellfacs-Thymus-Epithelium-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX18 TRIM6 SOX7 CA4 GPR4 APLP2

1.73e-041812016bce56e12ab93693c9c04fa6aad8f2e1dff0c4d45
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

POU6F2 TENM2 MAGI2 TMEM266 WDR49 ZFPM2

1.84e-041832016848fc6dd129150897ee339343e83c645b6e779eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TET2 DCN TENM2 MAGI2 TMEM266 WDR49

1.84e-041832016eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LVRN EPS8 SEMA6D FAT4 CCK HELZ2

1.84e-0418320166e6128c5be5e0a2db6d84eecbf4dddd02d0216f8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCN TENM2 MAGI2 TMEM266 WDR49 ZFPM2

1.84e-0418320167c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX18 ME1 PLEKHH1 DMD FAT4 RET

1.84e-041832016351d575339038bd4a66f408da518c567444208e8
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

STAT2 ZNF644 SYNE2 PRKD2 TRIM56 HELZ2

1.84e-0418320168f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

INTU CENPF SOWAHC DBF4 DIAPH3 DEPDC1

1.84e-041832016e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLITRK2 DMD DNAH9 FAT4 FRAS1 DNAH11

1.89e-0418420162cbed6462fea2622871bb7e49b0df3d984239281
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

POU6F2 TENM2 TMEM266 RET PTPRT SNTG1

1.89e-041842016658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCDC1 SH3RF2 DIAPH2 CA4 ZFPM2 R3HDM1

1.89e-04184201634e316ad8e7b8667cd8ad61397281802a252744f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLITRK2 DMD DNAH9 FAT4 FRAS1 DNAH11

1.89e-0418420162b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellnormal_Lung-Endothelial_cells-Tumor_ECs|normal_Lung / Location, Cell class and cell subclass

NKX2-3 SOX18 SOX7 EXOC3L2 GPR4 KIF4B

1.89e-0418420167ee98acda030366ac6cf3890a6d93fd0426712ed
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLITRK2 DMD DNAH9 FAT4 FRAS1 DNAH11

1.89e-041842016ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX18 SOX7 ITPRIPL1 CA4 GPR4 PPARG

1.95e-0418520164cfef50aeed5b3000ce5e864a41c13740b8267b1
ToppCelldroplet-Heart-nan-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NKX2-3 SOX18 CA4 GPR4 APLP2 PPARG

1.95e-041852016a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX18 SOX7 ITPRIPL1 CA4 GPR4 PPARG

1.95e-041852016c3105978d971da7d0fad1a717ee29afee5ed6357
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCN TENM2 MAGI2 TMEM266 WDR49 ZFPM2

1.95e-041852016b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX18 SOX7 ITPRIPL1 CA4 GPR4 PPARG

1.95e-04185201609256c6f42f59b7eb89160b2ea706172a5b743be
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

POU6F2 HERC2P3 TMEM266 RET PTPRT SNTG1

1.95e-0418520165a0340c25196453f19e424d346efbf66d2c53ac3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNQ1 FRAS1 OPHN1 SNTG1 EMX1 ABHD11

2.01e-041862016d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNQ1 FRAS1 VEPH1 OPHN1 SNTG1 EMX1

2.01e-04186201608632045d499e61dd96ff29a5a9a208afe58dc58
Diseaseuric acid measurement

TET2 INTU ABCA1 DCDC1 SWT1 TENM2 PLEKHH1 TMEM266 KCNQ1 PYGM EXOC3L2 PRKD2 FAT4 FRAS1 NAALAD2 PPARG NDUFAF6

6.68e-0761019417EFO_0004761
Diseasecongenital diaphragmatic hernia (implicated_via_orthology)

SOX7 NDST1 ZFPM2

5.89e-05121943DOID:3827 (implicated_via_orthology)
DiseaseBrain Tumor, Primary

ITGB2 IQGAP1 IL2 HES5

6.38e-05331944C0750974
DiseasePrimary malignant neoplasm of brain

ITGB2 IQGAP1 IL2 HES5

6.38e-05331944C0750979
DiseaseRecurrent Brain Neoplasm

ITGB2 IQGAP1 IL2 HES5

6.38e-05331944C0750977
DiseaseBenign neoplasm of brain, unspecified

ITGB2 IQGAP1 IL2 HES5

6.38e-05331944C0496899
DiseaseNeoplasms, Intracranial

ITGB2 IQGAP1 IL2 HES5

6.38e-05331944C1527390
DiseaseMalignant neoplasm of brain

ITGB2 IQGAP1 IL2 HES5

1.12e-04381944C0153633
DiseaseBrain Neoplasms

ITGB2 IQGAP1 IL2 HES5

1.24e-04391944C0006118
Diseaseamyloid-like protein 2 measurement

APLP2 ZFPM2

1.28e-0431942EFO_0801380
DiseaseN-palmitoyl-sphinganine (d18:0/16:0) measurement

SYNE2 DCAF12

1.28e-0431942EFO_0800428
Diseaseadenosine deaminase measurement

ADA2 TADA2A

1.28e-0431942EFO_0010761
Diseaseautosomal dominant auditory neuropathy 1 (implicated_via_orthology)

DIAPH2 DIAPH3

1.28e-0431942DOID:0060690 (implicated_via_orthology)
Diseaseintellectual disability (implicated_via_orthology)

KDM5B ZNF280B NDST1 ANK2 UBR4

1.39e-04751945DOID:1059 (implicated_via_orthology)
Diseaseprotein S100-A11 measurement

ADA2 TADA2A

2.56e-0441942EFO_0801958
Diseasevalerate measurement

KCNQ1 SEC23B

2.56e-0441942EFO_0021112
Diseaseprimary biliary cholangitis (implicated_via_orthology)

JAK2 PDE5A

2.56e-0441942DOID:12236 (implicated_via_orthology)
DiseaseMyelofibrosis

TET2 JAK2

2.56e-0441942C0026987
Diseaselymphocyte count

TET2 NKX2-3 ITGB2 LYST GAB2 IQGAP1 CCDC66 XPO6 ZNF644 GTF2IRD2 TADA2A EXOC3L2 HSPA6 DCAF12 FRAS1 PCDHGB7 PTPRT ZFPM2 GTF2IRD2B PKP3 NDUFAF6 IL2

2.69e-04146419422EFO_0004587
Diseaseinterleukin-17 receptor A measurement

ADA2 TADA2A

4.24e-0451942EFO_0801718
Diseaseplasminogen activator inhibitor 1 measurement

UBR4 PPARG ZFPM2 TRIM56

4.43e-04541944EFO_0004792
Diseaseparathyroid hormone-related protein measurement

ADA2 TADA2A

6.34e-0461942EFO_0020622
Diseaseclubfoot (implicated_via_orthology)

FRAS1 RET

6.34e-0461942DOID:11836 (implicated_via_orthology)
Diseasearylsulfatase B measurement

ADA2 TADA2A

6.34e-0461942EFO_0008030
DiseasePrimary Myelofibrosis

TET2 JAK2

6.34e-0461942C0001815
DiseaseCystic kidney

SDCCAG8 FAT4

6.34e-0461942C0022679
Diseasesevere acute respiratory syndrome, COVID-19

ABCC3 RBM26 LYST TENM2 MAGI2 DIAPH2 DMD ZFPM2 CASK MAML2

7.99e-0444719410EFO_0000694, MONDO_0100096
Diseaselong QT syndrome (is_implicated_in)

KCNQ1 ANK2

8.84e-0471942DOID:2843 (is_implicated_in)
DiseaseAlzheimer's disease 1 (implicated_via_orthology)

APLP1 APLP2

8.84e-0471942DOID:0080348 (implicated_via_orthology)
DiseaseMicrocephaly

KIFBP CENPF CASK LSS

1.00e-03671944C0025958
Diseaseresponse to ketamine

EVC XPO6 TMEM266 MROH2B

1.12e-03691944EFO_0009748
DiseaseUnilateral agenesis of kidney

FRAS1 RET

1.17e-0381942C0266294
Diseasepantothenate measurement

ABCA1 TENM2

1.17e-0381942EFO_0021034
Diseasecolorectal carcinoma (biomarker_via_orthology)

JAK2 IL2

1.17e-0381942DOID:0080199 (biomarker_via_orthology)
DiseasePolycythemia Vera

TET2 JAK2

1.17e-0381942C0032463
Diseasefatty liver disease (biomarker_via_orthology)

ABCC3 ABCA1 PPARG

1.32e-03331943DOID:9452 (biomarker_via_orthology)
Diseasenephronophthisis (implicated_via_orthology)

SDCCAG8 TTC21B

1.50e-0391942DOID:12712 (implicated_via_orthology)
Diseasecognitive disorder (is_implicated_in)

DMD PPARG

1.50e-0391942DOID:1561 (is_implicated_in)
Diseaselow tension glaucoma

ABCA1 ZFPM2

1.50e-0391942EFO_1001022
Diseasebehavioural disinhibition measurement

SEMA6D DNAH9 ZFPM2 DNAH11

1.53e-03751944EFO_0006946
Diseaseinterstitial lung disease (is_implicated_in)

SFTPC IL2

1.87e-03101942DOID:3082 (is_implicated_in)
Diseasebeta-defensin 1 measurement

LVRN CPN2

1.87e-03101942EFO_0801415
Diseasetemporomandibular joint disorder

DMD BAHCC1

1.87e-03101942EFO_0005279
Diseaseallergic rhinitis (biomarker_via_orthology)

ITGB2 IL2

1.87e-03101942DOID:4481 (biomarker_via_orthology)
DiseaseS-7-hydroxywarfarin to S-warfarin ratio measurement

KIFBP LPCAT1 MAGI2 PTPRT

2.03e-03811944EFO_0803334
Diseaseanti-SARS-CoV-2 IgG measurement, response to COVID-19 vaccine

ADA2 TADA2A

2.27e-03111942EFO_0803358, EFO_0803362
Diseaseinterleukin 17 receptor A measurement

ADA2 TADA2A

2.27e-03111942EFO_0008175
DiseaseCystic Kidney Diseases

SDCCAG8 FAT4

2.27e-03111942C1691228
DiseaseAnorectal Malformations

INTU JAK2 CASK

2.48e-03411943C3495676
Diseasehigh grade glioma (is_implicated_in)

KDM5B DCN IL2

2.66e-03421943DOID:3070 (is_implicated_in)
DiseaseTumoral calcinosis

ITGB2 JAK2 DMD

2.66e-03421943C0263628
DiseaseCalcinosis

ITGB2 JAK2 DMD

2.66e-03421943C0006663
DiseaseMicrocalcification

ITGB2 JAK2 DMD

2.66e-03421943C0521174
DiseaseThrombocythemia, Essential

TET2 JAK2

2.72e-03121942C0040028
DiseaseNeurobehavioral Manifestations

MAGI2 CCK

2.72e-03121942C0525041
DiseaseCongenital pontocerebellar hypoplasia

RARS2 CASK

3.20e-03131942C0266468
Diseaseautism spectrum disorder (implicated_via_orthology)

KDM5B ZNF280B SH3RF2 NDST1 CASK

3.39e-031521945DOID:0060041 (implicated_via_orthology)
DiseaseAcute Promyelocytic Leukemia

TET2 ITGB2 NUMA1

3.45e-03461943C0023487
Diseaseperiodontitis

ABCA1 UTP14A TENM2 DMD PTPRT ZFPM2

3.68e-032231946EFO_0000649
DiseaseMalformations of Cortical Development

KIFBP NDST1

3.72e-03141942C1955869
Diseasetetralogy of Fallot (implicated_via_orthology)

BMP10 ZFPM2

3.72e-03141942DOID:6419 (implicated_via_orthology)
Diseaseatrial fibrillation (is_implicated_in)

KCNQ1 ANK2

3.72e-03141942DOID:0060224 (is_implicated_in)
DiseaseCortical Dysplasia

KIFBP NDST1

3.72e-03141942C0431380
DiseaseCrohn Disease

NKX2-3 JAK2 PPARG

4.37e-03501943C0010346
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5B OPHN1

4.86e-03161942DOID:0050888 (implicated_via_orthology)
DiseaseRomano-Ward Syndrome

KCNQ1 ANK2

4.86e-03161942C0035828
Diseaseresponse to methotrexate

POU6F2 COMMD9

4.86e-03161942GO_0031427
Diseaseerythritol measurement

MAST2 DCP1A

5.48e-03171942EFO_0021171
Diseaselow affinity immunoglobulin gamma Fc region receptor II-a measurement

HSPA6 HSPA7

5.48e-03171942EFO_0021969
DiseaseNight blindness, congenital stationary

LRIT3 GRK1

5.48e-03171942C0339535
Diseasetrauma exposure measurement

TET2 POU6F2 TENM2 GSDME KCNQ1

5.70e-031721945EFO_0010703
DiseaseHOMA-B

ABCA1 DIAPH3 ZFPM2

5.71e-03551943EFO_0004469
DiseaseCiliopathies

SDCCAG8 EVC TTC21B DNAH11

6.08e-031101944C4277690
Diseasemelanoma

GAB2 FAT4 UBR4 RET PPARG IL2

6.13e-032481946C0025202
DiseaseAnorexia

CCK IL2

6.14e-03181942C0003123
DiseaseAlzheimer's disease (implicated_via_orthology)

ANK2 APLP1 APLP2

6.31e-03571943DOID:10652 (implicated_via_orthology)
Diseasecreatinine measurement

TET2 INTU DCDC1 CENPF SDCCAG8 EVC MAST2 GAB2 TMEM266 KCNQ1 DCAF12 PRKD2 SLC47A2 ULK3

6.32e-0399519414EFO_0004518
Diseaseurate measurement

ABCA1 DCDC1 MFHAS1 CLK4 TMEM266 KCNQ1 PYGM PRKD2 PPARG PTPRT ULK3 NISCH NDUFAF6

6.51e-0389519413EFO_0004531

Protein segments in the cluster

PeptideGeneStartEntry
LDPAKRISINQALQH

PRPF4B

986

Q13523
LVDKENINNTPKHFR

TTF1

106

Q15361
AVFHLQQLLERKPDN

TTC21B

971

Q7Z4L5
KDNIHFKPINTNLDR

ZNF280B

241

Q86YH2
VANLLFQELQPHFNK

EXOC3L2

171

Q2M3D2
AAQFQRKPEDQHLDL

BAHCC1

941

Q9P281
LAQNLLAQLPEELFH

CPN2

176

P22792
NESTPIQQLLEHFLR

BRD9

136

Q9H8M2
QHLDKILAFPQRQES

ABHD11

241

Q8NFV4
KQATLLLERNFHPFA

GSDME

286

O60443
QFDIQLLTHNDPKEL

GCLM

206

P48507
ITVKDLNDNSPHFLQ

FAT4

881

Q6V0I7
AFNHPLNLTKQQLSE

ABCA1

1631

O95477
NLPKADRQALNEHFQ

APLP1

341

P51693
NEVLHQPLSEAQRKS

ANKRD30A

1246

Q9BXX3
QEIPRDANHKLVFIS

DNAH11

116

Q96DT5
RKQTSRLDPHFLNNK

BTBD11

906

A6QL63
TPFLQLNEIRNVKHD

ANGPTL3

226

Q9Y5C1
FLGQVHLKADPDNLQ

CAPN5

591

O15484
KTQHLQELFSRIPFN

DDX20

296

Q9UHI6
KLVEPQISELNHRFA

DMD

1751

P11532
LPRNEIFFSNILHNI

LVRN

456

Q6Q4G3
EDPANQFLRLKRHVN

C3orf85

26

A0A1B0GTC6
KRDPQELLHNQQAFV

CEP170B

391

Q9Y4F5
KNLQNLDPSHRISDR

CCK

81

P06307
LERDIKKFPQAENQH

DIAPH2

926

O60879
NLIKHLPDQEQLNSL

DIAPH3

756

Q9NSV4
HNLVEPVNKDLEFQL

DCP1A

76

Q9NPI6
EDDIRQNFTQLPLHK

DBF4

441

Q9UBU7
PAHKSRIVENLQSFN

ATP2A3

681

Q93084
FKATINPQDHRELHL

AMPD3

501

Q01432
KELATLQRQSPEHNL

IQGAP1

431

P46940
RKVLQILQFQPDAAH

NBEAL1

1241

Q6ZS30
IDLHEFLVNTLKNNP

R3HDM1

151

Q15032
LEDLRQLDNFKHPQR

RBM12B

531

Q8IXT5
PELNNISKLNEHFSR

RBM26

541

Q5T8P6
EHALKALRLINNNPE

RBM28

551

Q9NW13
VALHDLPENLRNIKF

RFX4

296

Q33E94
PTQFEERHLKFLQQL

JAK2

841

O60674
HNASDLLIKPLENFR

OPHN1

106

O60890
QALLHNKIRSPQSFF

ABCC3

1046

O15438
VNDHAPQFRKDEINL

PCDHGB7

126

Q9Y5F8
KAQLHLDQVLTSPFN

ANK2

2161

Q01484
NLPKAERQTLIQHFQ

APLP2

421

Q06481
ASRNELHNLLDKPQL

ARL8B

106

Q9NVJ2
HATNNLQIIPDFSLK

ANKFY1

571

Q9P2R3
LEKNEFITLAHVNPQ

PAPOLB

406

Q9NRJ5
SKDAIILHQFARPNN

FAXC

96

Q5TGI0
IHLPETVEQLRKFNA

CASK

286

O14936
VDLENHFLQNKVDPN

DCDC1

651

M0R2J8
PFVHELRLSALQKAQ

LPCAT1

31

Q8NF37
QKHFNRQIPAAASLI

KCNQ1

361

P51787
KHRFLLLDRNQPEVT

FRAS1

3756

Q86XX4
NPHLNKDLAFTLEER

ME1

21

P48163
HPRKLLTQDLVQENY

MAGEA12

241

P43365
LPRTKHLLNVINENF

METAP2

396

P50579
FENPVLEAKRKLQQH

MAGI2

376

Q86UL8
LDVDHNQLTAFPRQL

MFHAS1

186

Q9Y4C4
QAANILLPSNTHKDR

NLRP11

431

P59045
NKHPAGQQLDEFLQL

MMS19

766

Q96T76
ESINFSILNKHIPDN

MTO1

246

Q9Y2Z2
FLRHNKDLVAQTAQP

FAM91A1

451

Q658Y4
LIATKEENRHLFLPQ

ZFPM2

951

Q8WW38
HQLFDQIPELKQDIS

KDM8

276

Q8N371
QKQSPLDIHLDSFVR

FSIP2

4296

Q5CZC0
KHTRLNVVAFLNELP

NXF1

456

Q9UBU9
ANVLHRDLKPANLFI

MAPK6

146

Q16659
FELIRKNQFNLEDPH

PDE5A

736

O76074
ANTPHLRELHLDNNK

DCN

266

P07585
EQEAQLLSQLKHPNI

NEK4

51

P51957
FDIFHPSLQQKNTLL

NDUFAF6

306

Q330K2
FLDHENANKILNRPK

F9

31

P00740
LLENEFHQILKNPND

HRNR

36

Q86YZ3
LQKAHEFLRLSQVPD

LSS

411

P48449
FPQQKDLDQVQLHLE

VEPH1

666

Q14D04
PKQEFLLNLHSEENI

DEPDC1

461

Q5TB30
LLNLHSEENIQKPFS

DEPDC1

466

Q5TB30
HFPKRLALDLDNNNL

NOD1

701

Q9Y239
KALFDTQNELRAHIP

NDST1

336

P52848
FKHDPTSANLLQLVR

PRKD2

96

Q9BZL6
VFNVTKENRNHLLPD

NTPCR

166

Q9BSD7
SNHPEDLQAANRLIK

GGA2

201

Q9UJY4
TFAAELHRLKQQPLF

TUBGCP4

306

Q9UGJ1
LLKDLLNRVEDFQQH

KDM5B

861

Q9UGL1
LHNNKITSVPNEALR

LRIT3

136

Q3SXY7
TKENLLDFIKHNQLP

P4HB

221

P07237
RSLNQHLQALLTPDK

NBPF1

121

Q3BBV0
LHPQLAEKKQQFRNL

NBPF1

566

Q3BBV0
LAQHLVQKLSPENDN

NBPF1

696

Q3BBV0
FPNKDALVRHQQLSD

RBM5

656

P52756
HRTDLFQRDPKNVLI

PIGK

286

Q92643
LHNLLRFLASDKPQE

GPR4

301

P46093
RFKEHVQNNLPRDLL

PRPF39

246

Q86UA1
AALNPHNTVFDAKRL

HSPA7

61

P48741
KAPHFLRLQNVEVNV

PTPRT

191

O14522
NLFFQRALQPAKLHS

INTU

436

Q9ULD6
HPLELSEKNFQLNQD

POMP

46

Q9Y244
AEKIAPQDQINRHLS

MAML2

781

Q8IZL2
LVRAQKEQPFNHDIN

FKBP6

276

O75344
QLAHKLAENNIQPIF

ITGB2

306

P05107
NKLSSRVFLDHNALP

ITGB2

361

P05107
PKAHSQAVEEFQNLL

ITPRIPL1

526

Q6GPH6
AILALFPENFHQNLK

COMMD9

81

Q9P000
ANLDKNILHSFVQLR

EXOC5

681

O00471
FEQIRKLNPAANHRL

GDE1

131

Q9NZC3
NLAQSKNFHLRPRDL

IL2

91

P60568
KNFHLRPRDLISNIN

IL2

96

P60568
QNKHNPLLIVFSDDQ

BMP10

246

O95393
PIQLHREQILAFSQK

CA4

241

P22748
SPHLLDQLKAQNQEL

CENPF

276

P49454
NPQEFVHLAKRLVSD

GLT1D1

291

Q96MS3
AAQQLPSLLKEREFH

DCAF12

71

Q5T6F0
VFPIDLAKTRLQNQH

SLC25A18

26

Q9H1K4
EQNHKFLLLQDKQPL

FRMPD3

231

Q5JV73
QFKANHAELILANPS

SQLE

316

Q14534
LLEHPFSAVKQELQR

CCDC66

316

A2RUB6
QNIFLHIVDLSDPKQ

DHRS12

91

A0PJE2
SNQVLKLVSDLRNHP

ADA2

411

Q9NZK5
NPRAAELFHQLSQAL

DNAJC17

46

Q9NVM6
ILSPAHAAQERKQIF

LYST

2751

Q99698
QDLTSKLLHQNPLER

MAST2

756

Q6P0Q8
LLQVASRQKHLPNDT

KIF4B

996

Q2VIQ3
PSQLLRLERAFEKNH

EMX1

201

Q04741
SKNELENFPLNTIQH

EPS8

121

Q12929
LSQQKRFLAQFPVHQ

EVC

856

P57679
APQQVQRHLSKLFDN

DNAH9

1621

Q9NYC9
AALNPHNTVFDAKRL

HSPA6

61

P17066
KENSFLPFQIDHIRQ

CLK4

251

Q9HAZ1
HKLNPSQNVAVREAL

HELZ2

2151

Q9BYK8
LFQQFLQSAEKHLPA

GRK1

71

Q15835
NNLAHFPTLKLASRN

GTF2IRD2

801

Q86UP8
NNLAHFPTLKLVSRN

GTF2IRD2B

801

Q6EKJ0
VNTHKLRLSPNEEAF

CEP295

6

Q9C0D2
PFSVKDILNLEQQHQ

NKX2-3

11

Q8TAU0
LEKSIQFALRQNLHE

PPHLN1

326

Q8NEY8
LQKQLTQPETHFGRE

DBNL

286

Q9UJU6
RDPDSHIVKKINNLN

KIFBP

496

Q96EK5
IPSLEALNRKVHNFQ

SFTPC

131

P11686
PSHQAKREIRFLELQ

NUMA1

171

Q14980
NDHSKKPLRIINLNF

GAB2

51

Q9UQC2
EEKLQSNPLQHLFEV

RARS2

191

Q5T160
AAQQPHLRKNTLLQD

RNF135

66

Q8IUD6
KRLAVQNPDLHNAEL

SOX7

61

Q9BT81
EIFKLELQNVPRHAS

TRMT2A

71

Q8IZ69
QDPESLLLQHNLRKF

STAT2

76

P52630
IAAHQRPDKQNLFAI

QTRT1

186

Q9BXR0
VPEQHKVFERQLQLA

TATDN2

606

Q93075
LNTQHILLLFRQDPD

SLC47A2

131

Q86VL8
DRLHQQEKENPDSFL

SYNE2

5521

Q8WXH0
QEKENPDSFLNHVLA

SYNE2

5526

Q8WXH0
KHFINNPLFASTLLN

TADA2A

116

O75478
LAQHLVQKLSPENDN

NBPF12

696

Q5TAG4
LLQDGNQEPFKVRLH

SNTG1

16

Q9NSN8
PELQQSHAVNQLKDL

SDCCAG8

66

Q86SQ7
PQALEILNAHFEKNT

POU6F2

616

P78424
ELQLKLNHPESSQLF

PPARG

446

P37231
LNHPESSQLFAKLLQ

PPARG

451

P37231
HLNNNKLEILREDTF

SLITRK2

116

Q9H156
ILELRNKEFKHSNNP

TENM2

1271

Q9NT68
LVNFANKHQLPVNID

SOWAHC

321

Q53LP3
FSHQDKLRQILSQPA

HERC2P3

1046

Q9BVR0
AHNPLTDKQIDQFLV

MTA1

201

Q13330
AIPAVHFINDSLKNQ

SWT1

446

Q5T5J6
LNRNLEKPVKTNFHE

MROH2B

406

Q7Z745
LLLEQEFARHQPNSK

HES5

41

Q5TA89
DNFRELVHIKPDQSN

SLC12A4

1001

Q9UP95
ENFKHLLQAPLDDAQ

SEC23B

681

Q15437
NFNHFQIERLLNKPG

AKR1B15

161

C9JRZ8
NFNHEQLERLLNKPG

AKR1E2

171

Q96JD6
DQNFLSRDQHVLPKD

CCDC15

476

Q0P6D6
DQNFLSRDQHVLPKD

CCDC15

506

Q0P6D6
RDLHVLSNDQNILPK

CCDC15

611

Q0P6D6
QAVPRLVKLFNHANQ

PKP3

361

Q9Y446
HLQARSLSEINKPNF

DNTTIP2

246

Q5QJE6
IEKSNLNRQFLFRPH

UBA6

501

A0AVT1
KFDLNEPLHLSFLQN

UBA6

746

A0AVT1
NLAVDFRQQLHPAQK

ZFP28

236

Q8NHY6
FVNHILPDLKSANVN

CSE1L

461

P55060
NTPLDAIAQFRKHID

TRAPPC11

286

Q7Z392
FKNLNLNAALHPDEI

USP16

576

Q9Y5T5
VHINPNSLFDIQVKR

PYGM

556

P11217
FRHNIRLQTPQKDCE

TNN

86

Q9UQP3
PLNALEEHNFLFQLR

TRAPPC14

306

Q8WVR3
VKLLNNENVAPFHSE

ZBTB41

171

Q5SVQ8
HIENCLFLPKRDTNL

WDR49

521

Q8IV35
FNLLRRKTHNEPFLA

HEATR9

371

A2RTY3
LLTPQHLNVIKADFN

NISCH

911

Q9Y2I1
RTPLEQEIFNLLHKN

UTP14A

181

Q9BVJ6
PEKFQHILRVLNTNI

RPS18

6

P62269
KHLQNLFVPRQEQGS

RALGAPB

121

Q86X10
KSFNLSPLHNLQNLE

TLR7

386

Q9NYK1
PAKAQHLLQQVLDRF

PLEKHH1

1161

Q9ULM0
DLLSEFNVLKQVNHP

RET

771

P07949
PQKASQHQVLFLLSD

ZNF644

166

Q9H582
HFEPQDAKAVLQLLR

UBL4B

101

Q8N7F7
PAFSFHQKQVLRQEL

ZCCHC14

6

Q8WYQ9
PKLLLSEDHQRAQFS

TRIM10

321

Q9UDY6
FVEPNLTARHLLEKN

SH3RF2

246

Q8TEC5
KRLAQQNPDLHNAVL

SOX18

101

P35713
QSFLQPDIHLFKQNL

XPO6

986

Q96QU8
RNTLNDLLKHLNDPN

SEMA6D

876

Q8NFY4
HRPQLENLLCKVNEA

UBR4

3756

Q5T4S7
NVIPKQDLLHRCFQE

TET2

871

Q6N021
IVPQNHSLLENDLKN

nan

131

Q499Y3
IREKNLAHPVIQNFS

TERF2

241

Q15554
FNLSEKRHDLTRLNP

TNS2

176

Q63HR2
PELEHRVSLFNQKNQ

TMEM266

476

Q2M3C6
QIIAFLNSKIPEDQH

UFL1

711

O94874
NPHTANLNLVLAKNR

TRIM6

306

Q9C030
KNCHLLRLSFEEQQP

TRIM56

361

Q9BRZ2
QFLHERNISHLDLKP

ULK3

126

Q6PHR2
VLFTQALKLNPQDHR

TTC31

326

Q49AM3
QNIHSPALLFKLAQD

ZSWIM4

636

Q9H7M6
FHKRLIQVDLNNPIA

NAALAD2

636

Q9Y3Q0