| Pubmed | Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease. | HIVEP2 OXR1 MYCBP2 PDGFRB IFT81 PSMD2 SMARCAD1 DNAAF9 CMYA5 JAK1 CRYL1 CS PAK2 CHD6 TNKS2 PC SLX4 KPNB1 | 5.10e-07 | 1285 | 121 | 18 | 35914814 |
| Pubmed | Defining the membrane proteome of NK cells. | CDK9 MYCBP2 PDGFRB ESYT1 PSMD2 HEATR1 ARPC3 ARF4 ACSL3 NBAS KSR1 GYS1 TNK2 HEATR5B DHX34 KPNB1 | 3.10e-06 | 1168 | 121 | 16 | 19946888 |
| Pubmed | Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis. | MYCBP2 ESYT1 PSMD2 ARPC3 ZNF169 ARF4 NBAS RTKN2 CS KMT2A PC SEC23A KPNB1 | 5.04e-06 | 807 | 121 | 13 | 30575818 |
| Pubmed | A central chaperone-like role for 14-3-3 proteins in human cells. | CDK9 HIVEP2 MYCBP2 MAP4 ESYT1 ARF4 KSR1 MAST4 AASS KMT2A CRYBG3 PC GARRE1 | 1.01e-05 | 861 | 121 | 13 | 36931259 |
| Pubmed | Mouse placenta fetal macrophages arise from endothelial cells outside the placenta. | PDGFRB PCDH12 EMCN | 1.15e-05 | 13 | 121 | 3 | 36473461 |
| Pubmed | A kinase-independent activity of Cdk9 modulates glucocorticoid receptor-mediated gene induction. | CDK9 NR3C1 | 1.20e-05 | 2 | 121 | 2 | 24559102 |
| Pubmed | Associations of glucocorticoid receptor and corticosteroid-binding globulin gene polymorphisms on fat mass and fat mass distribution in prepubertal obese children. | NR3C1 SERPINA6 | 1.20e-05 | 2 | 121 | 2 | 22576823 |
| Pubmed | Rethinking the Citric Acid Cycle: Connecting Pyruvate Carboxylase and Citrate Synthase to the Flow of Energy and Material. | CS PC | 1.20e-05 | 2 | 121 | 2 | 33435350 |
| Pubmed | The glucocorticoid receptor is essential for maintaining basal and dexamethasone-induced repression of the murine corticosteroid-binding globulin gene. | NR3C1 SERPINA6 | 1.20e-05 | 2 | 121 | 2 | 10509797 |
| Pubmed | Corticosteroid binding globulin gene polymorphism influences cortisol driven fat distribution in obese women. | NR3C1 SERPINA6 | 1.20e-05 | 2 | 121 | 2 | 16222046 |
| Pubmed | BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression. | MAP4 ESYT1 PSMD2 HEATR1 SLC2A1 ITIH4 ARF4 CS GYS1 PAK2 KMT2A CHD6 PC PYCR3 KIF22 KPNB1 | 1.40e-05 | 1318 | 121 | 16 | 30463901 |
| Pubmed | Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. | PCDH12 SLC2A1 GYS1 | 3.23e-05 | 18 | 121 | 3 | 31917811 |
| Pubmed | The mouse juvenile spermatogonial depletion (jsd) phenotype is due to a mutation in the X-derived retrogene, mUtp14b. | ACSL3 UTP14C | 3.59e-05 | 3 | 121 | 2 | 15289605 |
| Pubmed | The Lipoxin A4 receptor is coupled to SHP-2 activation: implications for regulation of receptor tyrosine kinases. | PDGFRB FPR2 | 3.59e-05 | 3 | 121 | 2 | 17403678 |
| Pubmed | Genetic interaction between central pair apparatus genes CFAP221, CFAP54, and SPEF2 in mouse models of primary ciliary dyskinesia. | CFAP54 CFAP221 | 3.59e-05 | 3 | 121 | 2 | 32704025 |
| Pubmed | DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans. | NBAS DHX34 | 3.59e-05 | 3 | 121 | 2 | 23828042 |
| Pubmed | Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury. | PADI4 FPR2 | 3.59e-05 | 3 | 121 | 2 | 29415887 |
| Pubmed | YXXL motifs in SH2-Bbeta are phosphorylated by JAK2, JAK1, and platelet-derived growth factor receptor and are required for membrane ruffling. | PDGFRB JAK1 | 3.59e-05 | 3 | 121 | 2 | 12551917 |
| Pubmed | JAK1/STAT3 activation directly inhibits IL-12 production in dendritic cells by preventing CDK9/P-TEFb recruitment to the p35 promoter. | CDK9 JAK1 | 3.59e-05 | 3 | 121 | 2 | 25931145 |
| Pubmed | Neddylation modification of the U3 snoRNA-binding protein RRP9 by Smurf1 promotes tumorigenesis. | PSMD2 ARF4 CS GYS1 KPNB1 | 5.76e-05 | 117 | 121 | 5 | 34662580 |
| Pubmed | Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism. | CCDC125 CDK9 RASGRP4 PSMD2 SPAG7 HEATR1 COLEC10 GCSH ACSL3 NBAS RTKN2 CS PAK2 KMT2A PC | 5.98e-05 | 1327 | 121 | 15 | 32694731 |
| Pubmed | Human brain-specific L-proline transporter: molecular cloning, functional expression, and chromosomal localization of the gene in human and mouse genomes. | PDGFRB NR3C1 | 7.17e-05 | 4 | 121 | 2 | 7651355 |
| Pubmed | VEGFR3 modulates brain microvessel branching in a mouse model of 22q11.2 deletion syndrome. | PDGFRB SLC2A1 | 7.17e-05 | 4 | 121 | 2 | 36216515 |
| Pubmed | Response Element Composition Governs Correlations between Binding Site Affinity and Transcription in Glucocorticoid Receptor Feed-forward Loops. | NR3C1 AASS | 7.17e-05 | 4 | 121 | 2 | 26088140 |
| Pubmed | Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins. | PDGFRB JAK1 | 7.17e-05 | 4 | 121 | 2 | 8657151 |
| Pubmed | UTP14c is a recently acquired retrogene associated with spermatogenesis and fertility in man. | ACSL3 UTP14C | 7.17e-05 | 4 | 121 | 2 | 16354793 |
| Pubmed | PDGFR-β-activated ACK1-AKT signaling promotes glioma tumorigenesis. | PDGFRB TNK2 | 7.17e-05 | 4 | 121 | 2 | 25257795 |
| Pubmed | The super elongation complex (SEC) family in transcriptional control. | CDK9 KMT2A | 7.17e-05 | 4 | 121 | 2 | 22895430 |
| Pubmed | A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export. | ESYT1 PSMD2 SLC2A1 ARF4 ACSL3 CS PC SEC23A | 7.21e-05 | 392 | 121 | 8 | 33144569 |
| Pubmed | Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function. | MYCBP2 MAP4 ESYT1 PSMD2 SMARCAD1 HEATR1 ELP3 SLC2A1 ARF4 ACSL3 CS DHX34 PYCR3 SEC23A KPNB1 | 7.43e-05 | 1353 | 121 | 15 | 29467282 |
| Pubmed | Spatial and chronological localization of septoclasts in the mouse Meckel's cartilage. | PDGFRB EMCN | 1.19e-04 | 5 | 121 | 2 | 35195769 |
| Pubmed | Protocadherin 12 (VE-cadherin 2) is expressed in endothelial, trophoblast, and mesangial cells. | PDGFRB PCDH12 | 1.19e-04 | 5 | 121 | 2 | 15541725 |
| Pubmed | DAXX, FLASH, and FAF-1 modulate mineralocorticoid and glucocorticoid receptor-mediated transcription in hippocampal cells--toward a basis for the opposite actions elicited by two nuclear receptors? | CASP8AP2 NR3C1 | 1.19e-04 | 5 | 121 | 2 | 14978255 |
| Pubmed | Rad5 and Its Human Homologs, HLTF and SHPRH, Are Novel Interactors of Mismatch Repair. | SMARCAD1 SHPRH | 1.19e-04 | 5 | 121 | 2 | 35784486 |
| Pubmed | Novel interactors and a role for supervillin in early cytokinesis. | PCNX3 KMT2A KIF22 | 1.26e-04 | 28 | 121 | 3 | 20309963 |
| Pubmed | Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation. | MAP4 PDGFRB ESYT1 PSMD2 SMARCAD1 HEATR1 CMYA5 SLC2A1 ARF4 ACSL3 CS PC SEC23A MGAM2 KPNB1 | 1.32e-04 | 1425 | 121 | 15 | 30948266 |
| Pubmed | Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. | CASP8AP2 MYCBP2 TOGARAM1 RHOBTB2 SETBP1 CHD6 | 1.42e-04 | 225 | 121 | 6 | 12168954 |
| Pubmed | Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. | CS GYS1 PC | 1.56e-04 | 30 | 121 | 3 | 31693883 |
| Pubmed | WNT5a-ROR Signaling Is Essential for Alveologenesis. | PDGFRB RTKN2 EMCN | 1.72e-04 | 31 | 121 | 3 | 32046118 |
| Pubmed | Recruitment of MLL1 complex is essential for SETBP1 to induce myeloid transformation. | SETBP1 KMT2A | 1.78e-04 | 6 | 121 | 2 | 35036869 |
| Pubmed | Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid. | PDGFRB SLC2A1 | 1.78e-04 | 6 | 121 | 2 | 24828044 |
| Pubmed | Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes. | CDK9 KMT2A | 1.78e-04 | 6 | 121 | 2 | 21896721 |
| Pubmed | An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. | CENPB MYCBP2 ESYT1 IFT81 STYXL2 HEATR1 ARPC3 ACSL3 KSR1 CS GYS1 RTL9 KPNB1 LARGE1 | 2.08e-04 | 1321 | 121 | 14 | 27173435 |
| Pubmed | Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex. | MAP4 PSMD2 ARF4 GYS1 KPNB1 | 2.23e-04 | 156 | 121 | 5 | 22952844 |
| Pubmed | Adhesion G protein-coupled receptor Gpr126/Adgrg6 is essential for placental development. | PCDH12 SLC2A1 EMCN | 2.27e-04 | 34 | 121 | 3 | 34767447 |
| Pubmed | Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor. | GRIK3 SLC2A1 | 2.49e-04 | 7 | 121 | 2 | 8921405 |
| Pubmed | Genetic variation in the hypothalamic-pituitary-adrenal stress axis influences susceptibility to musculoskeletal pain: results from the EPIFUND study. | NR3C1 SERPINA6 | 2.49e-04 | 7 | 121 | 2 | 19723618 |
| Pubmed | SKIP interacts with c-Myc and Menin to promote HIV-1 Tat transactivation. | CDK9 KMT2A | 2.49e-04 | 7 | 121 | 2 | 19818711 |
| Pubmed | Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling. | PDGFRB TNK2 | 2.49e-04 | 7 | 121 | 2 | 19815557 |
| Pubmed | Mfsd2a is critical for the formation and function of the blood-brain barrier. | PDGFRB SLC2A1 | 2.49e-04 | 7 | 121 | 2 | 24828040 |
| Pubmed | SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage. | CDK9 MYH7B ESYT1 PSMD2 NR3C1 ARF4 ACSL3 HEATR5B PYCR3 SEC23A KPNB1 | 2.56e-04 | 878 | 121 | 11 | 37223481 |
| Pubmed | Glucose metabolism induced by Bmp signaling is essential for murine skeletal development. | SLC2A1 EMCN | 3.32e-04 | 8 | 121 | 2 | 30446646 |
| Pubmed | Glomerular mesangial cell recruitment and function require the co-receptor neuropilin-1. | PDGFRB EMCN | 3.32e-04 | 8 | 121 | 2 | 28835419 |
| Pubmed | Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer. | CDK9 NRBF2 ARF4 KPNB1 | 3.48e-04 | 95 | 121 | 4 | 35896951 |
| Pubmed | Activation of Stat5 by platelet-derived growth factor (PDGF) is dependent on phosphorylation sites in PDGF beta-receptor juxtamembrane and kinase insert domains. | PDGFRB JAK1 | 4.25e-04 | 9 | 121 | 2 | 9484840 |
| Pubmed | Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. | ESYT1 VPS8 FARP2 RHOBTB2 | 4.39e-04 | 101 | 121 | 4 | 9872452 |
| Pubmed | Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. | MYCBP2 MAP4 PSMD2 HEATR1 TASOR2 ACSL3 KMT2A SEC23A KPNB1 | 4.80e-04 | 653 | 121 | 9 | 22586326 |
| Pubmed | A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription. | CDK9 KMT2A | 5.30e-04 | 10 | 121 | 2 | 20153263 |
| Pubmed | Foxc1 is required by pericytes during fetal brain angiogenesis. | PDGFRB SLC2A1 | 5.30e-04 | 10 | 121 | 2 | 23862012 |
| Pubmed | Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124. | PDGFRB SLC2A1 | 5.30e-04 | 10 | 121 | 2 | 21071672 |
| Pubmed | CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesis. | CDK9 KMT2A | 5.30e-04 | 10 | 121 | 2 | 22094252 |
| Pubmed | Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta. | NR3C1 KPNB1 | 5.30e-04 | 10 | 121 | 2 | 19581287 |
| Pubmed | Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study. | NR3C1 SERPINA6 | 5.30e-04 | 10 | 121 | 2 | 20403506 |
| Pubmed | A high-throughput approach for measuring temporal changes in the interactome. | CDK9 OXR1 MAP4 PSMD2 SMARCAD1 NR3C1 CMYA5 ELP3 ARPC3 CS PAK2 PYCR3 SEC23A KPNB1 | 5.49e-04 | 1455 | 121 | 14 | 22863883 |
| Pubmed | Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling. | CENPB MYCBP2 ESYT1 PSMD2 SMARCAD1 GCSH SLC2A1 ARF4 JAK1 ACSL3 GYS1 KIF22 KPNB1 | 5.99e-04 | 1297 | 121 | 13 | 33545068 |
| Pubmed | Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. | MAP4 ESYT1 PSMD2 ARF4 KPNB1 | 6.18e-04 | 195 | 121 | 5 | 17110338 |
| Pubmed | Monocytes re-enter the bone marrow during fasting and alter the host response to infection. | NR3C1 SLC2A1 | 6.47e-04 | 11 | 121 | 2 | 36827982 |
| Pubmed | Rasd1 interacts with Ear2 (Nr2f6) to regulate renin transcription. | CENPB RASD1 | 6.47e-04 | 11 | 121 | 2 | 21247419 |
| Pubmed | A concerted metabolic shift in early forebrain alters the CSF proteome and depends on MYC downregulation for mitochondrial maturation. | SLC2A1 CS | 6.47e-04 | 11 | 121 | 2 | 31575649 |
| Pubmed | Nuclear receptor coactivator p160 proteins enhance the HIV-1 long terminal repeat promoter by bridging promoter-bound factors and the Tat-P-TEFb complex. | CDK9 NR3C1 | 6.47e-04 | 11 | 121 | 2 | 11704662 |
| Pubmed | Mesenchymal cell replacement corrects thymic hypoplasia in murine models of 22q11.2 deletion syndrome. | PDGFRB EMCN | 6.47e-04 | 11 | 121 | 2 | 36136514 |
| Pubmed | Death receptors DR6 and TROY regulate brain vascular development. | PDGFRB SLC2A1 | 6.47e-04 | 11 | 121 | 2 | 22340501 |
| Pubmed | Genetics of rheumatoid arthritis contributes to biology and drug discovery. | PADI4 GRHL2 WDFY4 RTKN2 | 6.48e-04 | 112 | 121 | 4 | 24390342 |
| Pubmed | Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics. | MAP4 ESYT1 SLC2A1 JAK1 ACSL3 GYS1 SEC23A | 7.11e-04 | 422 | 121 | 7 | 27342126 |
| Pubmed | Hepatocyte growth factor-regulated tyrosine kinase substrate is essential for endothelial cell polarity and cerebrovascular stability. | PDGFRB EMCN | 7.74e-04 | 12 | 121 | 2 | 32044971 |
| Pubmed | Glucocorticoid regulates mesenchymal cell differentiation required for perinatal lung morphogenesis and function. | NR3C1 EMCN | 7.74e-04 | 12 | 121 | 2 | 32460513 |
| Pubmed | Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway. | SLC2A1 EMCN | 7.74e-04 | 12 | 121 | 2 | 17418408 |
| Pubmed | Mass spectrometry-based proteomic analysis of FSCN1-interacting proteins in laryngeal squamous cell carcinoma cells. | ELP3 ARPC3 ARF4 PAK2 | 8.39e-04 | 120 | 121 | 4 | 31298480 |
| Pubmed | Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. | CENPB ESYT1 IFT81 SMARCAD1 HEATR1 NR3C1 ELP3 CASZ1 FOXB1 KIF22 | 8.48e-04 | 857 | 121 | 10 | 25609649 |
| Pubmed | HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways. | ESYT1 PSMD2 SMARCAD1 HEATR1 ARF4 ACSL3 PYCR3 KPNB1 | 8.94e-04 | 571 | 121 | 8 | 37167062 |
| Pubmed | Transcriptional and posttranscriptional regulation of HIV-1 gene expression. | CDK9 KPNB1 | 9.13e-04 | 13 | 121 | 2 | 22355797 |
| Pubmed | A hypomorphic allele of Tsc2 highlights the role of TSC1/TSC2 in signaling to AKT and models mild human TSC2 alleles. | PDGFRB EMCN | 9.13e-04 | 13 | 121 | 2 | 19357198 |
| Pubmed | Identification and sequencing the juvenile spermatogonial depletion critical interval on mouse chromosome 1 reveals the presence of eight candidate genes. | ACSL3 UTP14C | 9.13e-04 | 13 | 121 | 2 | 11700028 |
| Pubmed | miR-126 regulates glycogen trophoblast proliferation and DNA methylation in the murine placenta. | PCDH12 EMCN | 9.13e-04 | 13 | 121 | 2 | 30771304 |
| Pubmed | Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics. | CDK9 PSMD2 ELP3 ACSL3 CS GYS1 HEATR5B KPNB1 | 9.14e-04 | 573 | 121 | 8 | 28330616 |
| Pubmed | Identifying biological pathways that underlie primordial short stature using network analysis. | MYCBP2 MAP4 PSMD2 HEATR1 ARPC3 ACSL3 CS HEATR5B SEC23A KIF22 KPNB1 | 9.18e-04 | 1024 | 121 | 11 | 24711643 |
| Pubmed | Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers. | CDK9 KCTD9 CABP5 ARF4 ACSL3 PAK2 PCSK7 KMT2A SEC23A | 1.06e-03 | 730 | 121 | 9 | 34857952 |
| Pubmed | A multipoint genetic linkage map of mouse chromosome 18. | PDGFRB NR3C1 | 1.06e-03 | 14 | 121 | 2 | 1354640 |
| Pubmed | Protein kinase PKR is required for platelet-derived growth factor signaling of c-fos gene expression via Erks and Stat3. | PDGFRB JAK1 | 1.06e-03 | 14 | 121 | 2 | 11350938 |
| Pubmed | Angiopoietin-1 Is Required for Vortex Vein and Choriocapillaris Development in Mice. | PDGFRB EMCN | 1.06e-03 | 14 | 121 | 2 | 36172864 |
| Pubmed | MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia. | CDK9 KMT2A | 1.06e-03 | 14 | 121 | 2 | 20854876 |
| Pubmed | Overexpression of thioredoxin-1 reduces oxidative stress in the placenta of transgenic mice and promotes fetal growth via glucose metabolism. | NR3C1 SLC2A1 | 1.06e-03 | 14 | 121 | 2 | 18450962 |
| Pubmed | Mapping of the genes for four members of the transmembrane 4 superfamily: mouse Cd9, Cd63, Cd81, and Cd82. | PDGFRB NR3C1 | 1.06e-03 | 14 | 121 | 2 | 7590978 |
| Pubmed | A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis. | PDGFRB SLC2A1 | 1.22e-03 | 15 | 121 | 2 | 28535372 |
| Pubmed | Parvins Are Required for Endothelial Cell-Cell Junctions and Cell Polarity During Embryonic Blood Vessel Formation. | SLC2A1 EMCN | 1.22e-03 | 15 | 121 | 2 | 29567677 |
| Pubmed | Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis. | PDGFRB EMCN | 1.22e-03 | 15 | 121 | 2 | 37023750 |
| Pubmed | At Term, XmO and XpO Mouse Placentas Show Differences in Glucose Metabolism in the Trophectoderm-Derived Outer Zone. | SLC2A1 EMCN | 1.22e-03 | 15 | 121 | 2 | 28680878 |
| Pubmed | CDK7/GRP78 signaling axis contributes to tumor growth and metastasis in osteosarcoma. | IFT81 SMARCAD1 ARPC3 PC PYCR3 KIF22 KPNB1 | 1.29e-03 | 468 | 121 | 7 | 36042349 |
| Pubmed | Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells. | TASOR2 ARF4 RTL9 PRDM12 KMT2A CHD6 KPNB1 | 1.31e-03 | 469 | 121 | 7 | 27634302 |
| Pubmed | HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis. | CDK9 CASP8AP2 PSMD2 HEATR1 ITIH4 ACSL3 CS SHPRH CHD6 | 1.32e-03 | 754 | 121 | 9 | 35906200 |
| Cytoband | 4q24 | SLC9B1 MTTP EMCN | 1.01e-04 | 34 | 121 | 3 | 4q24 |
| Cytoband | Ensembl 112 genes in cytogenetic band chr3q27 | EEF1AKMT4-ECE2 VPS8 HTR3E PSMD2 | 3.81e-04 | 128 | 121 | 4 | chr3q27 |
| Drug | diclofenac sodium; Down 200; 10uM; MCF7; HG-U133A | TCEA2 MAP4 PCSK7 KMT2A TNK2 PYCR3 LRRC23 KPNB1 LARGE1 | 8.86e-07 | 195 | 119 | 9 | 333_DN |
| Disease | Intellectual Disability | HIVEP2 OXR1 PDGFRB PEX6 PCDH12 SLC2A1 AASS RHOBTB2 SETBP1 CNDP1 LARGE1 | 1.48e-06 | 447 | 115 | 11 | C3714756 |
| Disease | Burkitt Lymphoma | SALL3 KMT2A PC | 3.75e-04 | 36 | 115 | 3 | C0006413 |
| Disease | Leukemia, Myelocytic, Acute | TCEA2 JAK1 SETBP1 KMT2A SLX4 | 5.97e-04 | 173 | 115 | 5 | C0023467 |
| Disease | Prostatic Neoplasms | SMARCAD1 NR3C1 TLR6 CASZ1 JAK1 CRYL1 RASD1 KMT2A CHD6 | 7.03e-04 | 616 | 115 | 9 | C0033578 |
| Disease | Malignant neoplasm of prostate | SMARCAD1 NR3C1 TLR6 CASZ1 JAK1 CRYL1 RASD1 KMT2A CHD6 | 7.03e-04 | 616 | 115 | 9 | C0376358 |
| Disease | Varicose veins | TCEA2 PSMD2 CMYA5 CASZ1 KMT2A | 9.75e-04 | 193 | 115 | 5 | HP_0002619 |
| Disease | African Burkitt's lymphoma | SALL3 PC | 1.53e-03 | 15 | 115 | 2 | C0343640 |
| Disease | Burkitt Leukemia | SALL3 PC | 1.53e-03 | 15 | 115 | 2 | C4721444 |
| Disease | very low density lipoprotein cholesterol measurement, lipid measurement | NRBF2 MTTP PCSK7 TNKS2 KPNB1 | 1.74e-03 | 220 | 115 | 5 | EFO_0004529, EFO_0008317 |
| Disease | Global developmental delay | OXR1 SLC2A1 NBAS RHOBTB2 | 1.85e-03 | 133 | 115 | 4 | C0557874 |
| Disease | triglyceride measurement, very low density lipoprotein cholesterol measurement | TCEA2 NRBF2 MTTP PCSK7 TNKS2 | 1.88e-03 | 224 | 115 | 5 | EFO_0004530, EFO_0008317 |
| Disease | very low density lipoprotein cholesterol measurement, phospholipid measurement | NRBF2 MTTP PCSK7 TNKS2 KPNB1 | 2.07e-03 | 229 | 115 | 5 | EFO_0004639, EFO_0008317 |
| Disease | Profound Mental Retardation | PEX6 SLC2A1 SETBP1 CNDP1 | 2.18e-03 | 139 | 115 | 4 | C0020796 |
| Disease | Mental Retardation, Psychosocial | PEX6 SLC2A1 SETBP1 CNDP1 | 2.18e-03 | 139 | 115 | 4 | C0025363 |
| Disease | Mental deficiency | PEX6 SLC2A1 SETBP1 CNDP1 | 2.18e-03 | 139 | 115 | 4 | C0917816 |
| Disease | Myeloid Leukemia | SETBP1 KMT2A | 2.21e-03 | 18 | 115 | 2 | C0023470 |
| Disease | Leukemia, Monocytic, Chronic | SETBP1 KMT2A | 2.21e-03 | 18 | 115 | 2 | C0023466 |
| Disease | response to ketamine | NR3C1 TNKS2 LARGE1 | 2.51e-03 | 69 | 115 | 3 | EFO_0009748 |
| Disease | basophil count, eosinophil count | RASGRP4 PSMD2 FARP2 JAK1 PAK2 | 2.58e-03 | 241 | 115 | 5 | EFO_0004842, EFO_0005090 |
| Disease | Paroxysmal atrial fibrillation | NR3C1 CASZ1 SLC9B1 PAK2 | 3.30e-03 | 156 | 115 | 4 | C0235480 |
| Disease | familial atrial fibrillation | NR3C1 CASZ1 SLC9B1 PAK2 | 3.30e-03 | 156 | 115 | 4 | C3468561 |
| Disease | Persistent atrial fibrillation | NR3C1 CASZ1 SLC9B1 PAK2 | 3.30e-03 | 156 | 115 | 4 | C2585653 |
| Disease | hypertrophic cardiomyopathy (is_implicated_in) | MYH7B CS | 3.31e-03 | 22 | 115 | 2 | DOID:11984 (is_implicated_in) |
| Disease | Atrial Fibrillation | NR3C1 CASZ1 SLC9B1 PAK2 | 3.61e-03 | 160 | 115 | 4 | C0004238 |
