Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphoric diester hydrolase activity	PDE3A PDE3B SMPD1 PLCH1 TDP1 PLCE1	3.78e-05	97	128	6	GO:0008081
GeneOntologyMolecularFunction	3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity	PDE3A PDE3B	4.08e-05	2	128	2	GO:0004119
GeneOntologyBiologicalProcess	protein localization to organelle	LONP2 NUP88 NUP98 PEX7 CEP192 STIL CUBN EDN1 SH3BP4 MICALL1 GLMP NDUFA13 TBC1D32 VPS13D UBE2J2 PIK3R1 TRAM1 SUN2 EHD1 LRP2 AKAP1	3.54e-06	1091	128	21	GO:0033365
GeneOntologyBiologicalProcess	endocytic hemoglobin import into cell	CUBN LRP2	3.82e-05	2	128	2	GO:0020028
GeneOntologyBiologicalProcess	intracellular transport	TPCN2 WAS LONP2 NUP88 NUP98 PEX7 EHD3 MICALL1 NDUFA13 VPS13D WDR11 PIK3R1 TRAM1 SUN2 NUP210 EHD1 LRP2 TRAPPC10 AKAP1 NUP160 DYNC1H1 DOP1A UEVLD	4.43e-05	1496	128	23	GO:0046907
GeneOntologyCellularComponent	ciliary pocket membrane	EHD3 EHD1	1.13e-04	3	129	2	GO:0020018
GeneOntologyCellularComponent	ciliary pocket	EHD3 EHD1	1.13e-04	3	129	2	GO:0020016
Domain	EHD1/EHD3	EHD3 EHD1	4.59e-05	2	127	2	IPR029951
Pathway	REACTOME_GENE_SILENCING_BY_RNA	NUP88 NUP98 TNRC6B NUP210 NUP160	1.79e-05	49	94	5	MM14837
Pathway	REACTOME_SNRNP_ASSEMBLY	NUP88 NUP98 NUP210 WDR77 NUP160	2.89e-05	54	94	5	M29594
Pathway	BIOCARTA_NO1_PATHWAY	PDE3A PDE3B FLT4 CHRNA1	3.36e-05	28	94	4	M4383
Pathway	REACTOME_SNRNP_ASSEMBLY	NUP88 NUP98 NUP210 WDR77 NUP160	4.10e-05	58	94	5	MM14736
Pathway	REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN	NUP88 NUP98 NUP210 NUP160	5.78e-05	32	94	4	M29579
Pathway	REACTOME_EXPORT_OF_VIRAL_RIBONUCLEOPROTEINS_FROM_NUCLEUS	NUP88 NUP98 NUP210 NUP160	6.54e-05	33	94	4	M27016
Pathway	REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN	NUP88 NUP98 NUP210 NUP160	7.38e-05	34	94	4	M27041
Pathway	REACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS	NUP88 NUP98 NUP210 NUP160	8.29e-05	35	94	4	M27320
Pathway	REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA	NUP88 NUP98 NUP210 NUP160	9.27e-05	36	94	4	M26974
Pathway	REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY	NUP88 NUP98 NUP210 NUP160	9.27e-05	36	94	4	M27245
Pathway	REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS	NUP88 NUP98 NUP210 NUP160	1.03e-04	37	94	4	M1029
Pathway	REACTOME_INTERACTIONS_OF_REV_WITH_HOST_CELLULAR_PROTEINS	NUP88 NUP98 NUP210 NUP160	1.03e-04	37	94	4	M27038
Pathway	REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS	NUP88 NUP98 NUP210 NUP160	1.28e-04	39	94	4	M27238
Pathway	REACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY	NUP88 NUP98 NUP210 NUP160	1.41e-04	40	94	4	MM14945
Pathway	REACTOME_NS1_MEDIATED_EFFECTS_ON_HOST_PATHWAYS	NUP88 NUP98 NUP210 NUP160	1.55e-04	41	94	4	M29574
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS	NUP88 NUP98 NUP210 NUP160	1.55e-04	41	94	4	MM15200
Pathway	REACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS	NUP88 NUP98 NUP210 NUP160	1.71e-04	42	94	4	MM15039
Pathway	REACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA	NUP88 NUP98 NUP210 NUP160	1.87e-04	43	94	4	MM14609
Pathway	REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS	NUP88 NUP98 NUP210 NUP160	1.87e-04	43	94	4	M26975
Pathway	REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS	NUP88 NUP98 NUP210 NUP160	2.05e-04	44	94	4	M109
Pathway	REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS	NUP88 NUP98 NUP210 NUP160	2.44e-04	46	94	4	M27397
Pathway	REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS	NUP88 NUP98 NUP210 NUP160	2.66e-04	47	94	4	M27395
Pathway	REACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS	NUP88 NUP98 NUP210 NUP160	2.66e-04	47	94	4	MM14939
Pathway	REACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS	NUP88 NUP98 NUP210 NUP160	3.38e-04	50	94	4	MM14610
Pathway	REACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS	NUP88 NUP98 NUP210 NUP160	3.65e-04	51	94	4	MM15151
Pathway	PID_HEDGEHOG_2PATHWAY	STIL PIK3R1 LRP2	4.03e-04	22	94	3	M211
Pathway	REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN	NUP88 NUP98 NUP210 NUP160	4.23e-04	53	94	4	M27212
Pathway	REACTOME_NUCLEAR_ENVELOPE_BREAKDOWN	NUP88 NUP98 NUP210 NUP160	4.87e-04	55	94	4	MM14917
Pathway	REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES	NUP88 NUP98 OAS3 FANCG NUP210 NUP160	5.13e-04	151	94	6	M550
Pathway	REACTOME_SLC_TRANSPORTER_DISORDERS	SLC2A9 NUP88 NUP98 NUP210 NUP160	5.17e-04	99	94	5	M27474
Pathway	REACTOME_AMPLIFICATION_OF_SIGNAL_FROM_THE_KINETOCHORES	NUP98 PPP2R5E BUB1 NUP160 DYNC1H1	5.41e-04	100	94	5	MM14561
Pathway	REACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS	NUP88 NUP98 NUP210 NUP160	5.97e-04	58	94	4	MM15149
Pathway	REACTOME_TRNA_PROCESSING_IN_THE_NUCLEUS	NUP88 NUP98 NUP210 NUP160	6.37e-04	59	94	4	M27606
Pathway	REACTOME_MITOTIC_SPINDLE_CHECKPOINT	NUP98 PPP2R5E BUB1 NUP160 DYNC1H1	8.70e-04	111	94	5	M27673
Pathway	REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS	NUP88 NUP98 NUP210 NUP160	9.20e-04	65	94	4	MM15147
Pathway	KEGG_MEDICUS_REFERENCE_NUCLEAR_EXPORT_OF_MRNA	NUP88 NUP210 NUP160	1.02e-03	30	94	3	M47752
Pathway	REACTOME_MITOTIC_SPINDLE_CHECKPOINT	NUP98 PPP2R5E BUB1 NUP160 DYNC1H1	1.10e-03	117	94	5	MM15387
Pathway	REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS	NUP88 NUP98 NUP210 NUP160	1.28e-03	71	94	4	M27394
Pathway	REACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE	NUP88 NUP98 NUP210 NUP160	1.42e-03	73	94	4	MM14948
Pathway	WP_GLYCOGEN_METABOLISM	PHKA2 PTPA PPP2R5E	1.48e-03	34	94	3	MM15985
Pathway	REACTOME_ISG15_ANTIVIRAL_MECHANISM	NUP88 NUP98 NUP210 NUP160	1.49e-03	74	94	4	M48006
Pubmed	EHD3 Protein Is Required for Tubular Recycling Endosome Stabilization, and an Asparagine-Glutamic Acid Residue Pair within Its Eps15 Homology (EH) Domain Dictates Its Selective Binding to NPF Peptides.	EHD3 MICALL1 EHD1	2.13e-07	4	132	3	27189942
Pubmed	MICAL-L1 links EHD1 to tubular recycling endosomes and regulates receptor recycling.	EHD3 MICALL1 EHD1	1.06e-06	6	132	3	19864458
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	ERBB3 PDE3B LONP2 NOL9 CEMIP2 SH3BP4 PHKA2 MOGS WDR11 TRAM1 BUB1 PLCH1 PLCE1	1.27e-06	650	132	13	38777146
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	BMS1 NUP98 MUC16 TNRC6B CEP192 CEMIP2 SH3BP4 WDR11 EHD1 OCLN AKAP1 GCN1 NUP160 DYNC1H1	1.66e-06	777	132	14	35844135
Pubmed	Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase.	NUP88 NUP98 NUP210 NUP160	2.36e-06	25	132	4	10601273
Pubmed	Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.	NUP88 NUP98 NUP210 NUP160	2.78e-06	26	132	4	12228227
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	PDE3B BMS1 CEP192 NOL9 CEMIP2 SH3BP4 MICALL1 TBC1D31 MOGS WDR11 ERAL1 PIK3R1 TRAM1 SUN2 NUP210 OCLN PLCH1 AKAP1 SNTB1	3.61e-06	1487	132	19	33957083
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	PRAMEF5 CEP192 NOL9 CUBN EHD3 LARP4B PPP2R5E TBC1D31 ERAL1 PIK3R1 LRP2 TRAPPC10 HMGXB3 TFB2M D2HGDH PRAMEF6	3.80e-06	1084	132	16	11544199
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	NUP88 LARS1 NOL9 ECM1 MYOF PTPRF ERAL1 NUP210 TFB2M AKAP1 WDR77 NUP160 DYNC1H1	6.38e-06	754	132	13	35906200
Pubmed	Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network.	ERAP1 MOGS ERAL1 SUN2 PCSK6 NUP210 GCN1 NUP160	1.31e-05	282	132	8	35007762
Pubmed	Peering through the pore: nuclear pore complex structure, assembly, and function.	NUP88 NUP98 NUP210 NUP160	1.32e-05	38	132	4	12791264
Pubmed	Novel functions for the endocytic regulatory proteins MICAL-L1 and EHD1 in mitosis.	MICALL1 EHD1	1.43e-05	2	132	2	25287187
Pubmed	Muscarinic receptors mediate phospholipase C-dependent activation of protein kinase B via Ca2+, ErbB3, and phosphoinositide 3-kinase in 1321N1 astrocytoma cells.	ERBB3 PIK3R1	1.43e-05	2	132	2	11694521
Pubmed	Expression and immunolocalisation of the endocytic receptors megalin and cubilin in the human yolk sac and placenta across gestation.	CUBN LRP2	1.43e-05	2	132	2	23978537
Pubmed	Polymorphisms in LRP2 and CUBN genes and their association with serum vitamin D levels and sleep apnea.	CUBN LRP2	1.43e-05	2	132	2	38008818
Pubmed	Megalin and cubilin in the human gallbladder epithelium.	CUBN LRP2	1.43e-05	2	132	2	18791690
Pubmed	Megalin and cubilin: multifunctional endocytic receptors.	CUBN LRP2	1.43e-05	2	132	2	11994745
Pubmed	Megalin acts in concert with cubilin to mediate endocytosis of high density lipoproteins.	CUBN LRP2	1.43e-05	2	132	2	10766831
Pubmed	A pathophysiological role of PDE3 in allergic airway inflammation.	PDE3A PDE3B	1.43e-05	2	132	2	29367458
Pubmed	Cubilin and megalin expression and their interaction in the rat intestine: effect of thyroidectomy.	CUBN LRP2	1.43e-05	2	132	2	11595644
Pubmed	Acute endotoxemia in mice induces downregulation of megalin and cubilin in the kidney.	CUBN LRP2	1.43e-05	2	132	2	22437417
Pubmed	SUMOylation of EHD3 Modulates Tubulation of the Endocytic Recycling Compartment.	EHD3 EHD1	1.43e-05	2	132	2	26226295
Pubmed	Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells.	ERBB3 PIK3R1	1.43e-05	2	132	2	20007781
Pubmed	Chemoresistant tumor cell lines display altered epidermal growth factor receptor and HER3 signaling and enhanced sensitivity to gefitinib.	ERBB3 PIK3R1	1.43e-05	2	132	2	18803287
Pubmed	Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice.	PDE3A PDE3B	1.43e-05	2	132	2	17482796
Pubmed	[Deguelin regulates cell cycle and nuclear pore complex protein Nup98 and Nup88 in U937 cells in vitro].	NUP88 NUP98	1.43e-05	2	132	2	17650673
Pubmed	Targeted disruption of PDE3B, but not PDE3A, protects murine heart from ischemia/reperfusion injury.	PDE3A PDE3B	1.43e-05	2	132	2	25877153
Pubmed	Expression and role of cubilin in the internalization of nutrients during the peri-implantation development of the rodent embryo.	CUBN LRP2	1.43e-05	2	132	2	15616221
Pubmed	Phosphodiesterase type 3A (PDE3A), but not type 3B (PDE3B), contributes to the adverse cardiac remodeling induced by pressure overload.	PDE3A PDE3B	1.43e-05	2	132	2	31051182
Pubmed	Disruption of the FG nucleoporin NUP98 causes selective changes in nuclear pore complex stoichiometry and function.	NUP88 NUP98	1.43e-05	2	132	2	11248054
Pubmed	Pde3a and Pde3b regulation of murine pulmonary artery smooth muscle cell growth and metabolism.	PDE3A PDE3B	1.43e-05	2	132	2	39435735
Pubmed	Molecular basis for the anchoring of proto-oncoprotein Nup98 to the cytoplasmic face of the nuclear pore complex.	NUP88 NUP98	1.43e-05	2	132	2	22480613
Pubmed	Role of megalin and cubilin in the metabolism of vitamin D(3).	CUBN LRP2	1.43e-05	2	132	2	21595846
Pubmed	Differential distribution of cubilin and megalin expression in the mouse embryo.	CUBN LRP2	1.43e-05	2	132	2	14983511
Pubmed	Agonist-induced association of the p21ras GTPase-activating protein with phosphatidylinositol 3-kinase.	RASA1 PIK3R1	1.43e-05	2	132	2	1336372
Pubmed	Association Analysis of the Cubilin (CUBN) and Megalin (LRP2) Genes with ESRD in African Americans.	CUBN LRP2	1.43e-05	2	132	2	27197912
Pubmed	Characterization of an epithelial approximately 460-kDa protein that facilitates endocytosis of intrinsic factor-vitamin B12 and binds receptor-associated protein.	CUBN LRP2	1.43e-05	2	132	2	9334227
Pubmed	Phosphodiesterase 3A (PDE3A) deletion suppresses proliferation of cultured murine vascular smooth muscle cells (VSMCs) via inhibition of mitogen-activated protein kinase (MAPK) signaling and alterations in critical cell cycle regulatory proteins.	PDE3A PDE3B	1.43e-05	2	132	2	21632535
Pubmed	The phosphatidylinositol 3'-kinase pathway is a dominant growth factor-activated cell survival pathway in LNCaP human prostate carcinoma cells.	ERBB3 PIK3R1	1.43e-05	2	132	2	10383151
Pubmed	Silencing megalin and cubilin genes inhibits myeloma light chain endocytosis and ameliorates toxicity in human renal proximal tubule epithelial cells.	CUBN LRP2	1.43e-05	2	132	2	18448595
Pubmed	MICAL-L1 coordinates ciliogenesis by recruiting EHD1 to the primary cilium.	MICALL1 EHD1	1.43e-05	2	132	2	31615969
Pubmed	Relationship of urinary endothelin-1 with estimated glomerular filtration rate in autosomal dominant polycystic kidney disease: a pilot cross-sectional analysis.	ENGASE EDN1	1.43e-05	2	132	2	26923419
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	ERBB3 CEMIP2 SH3BP4 EHD3 MICALL1 MYOF PTPRF EHD1 SNTB1	1.48e-05	377	132	9	38117590
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	PDE3B NUP88 LARS1 NUP98 NDUFA13 LARP4B PPP2R5E PTPRF MOGS PCSK6 NUP210 OCLN GCN1 DYNC1H1	1.48e-05	942	132	14	31073040
Pubmed	Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure.	NUP88 NUP98 NUP210 NUP160	1.63e-05	40	132	4	37516964
Pubmed	Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.	TPCN2 SLC2A9 PTPA FCGBP CSMD1	1.77e-05	84	132	5	15203218
Pubmed	The transcription factor Sox10 is a key regulator of peripheral glial development.	ERBB3 DCT SLC18A3	1.89e-05	14	132	3	11156606
Pubmed	A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.	PTGES2 NUP88 NUP98 LARP4B MOGS SUN2 PCSK6 NUP210	1.94e-05	298	132	8	32353859
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MYOF LARP4B VPS13D WDR11 SUN2 NUP210 KLHL14 PLCH1 NUP160 DOP1A	2.00e-05	493	132	10	15368895
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	SPEG LARS1 CEMIP2 WDR11 STARD9 KLHL14	2.73e-05	153	132	6	10718198
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	BMS1 TNRC6B NDUFA13 MOGS SUN2 NUP210 GCN1 WDR77 NUP160	2.75e-05	408	132	9	33766124
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	PTGES2 BMS1 NUP88 NUP98 TNRC6B LARP4B MOGS WDR11 SUN2 PCSK6 NUP210 GCN1	3.22e-05	754	132	12	33060197
Pubmed	The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.	ABCA4 ERAP1 ECM1 CEMIP2 EHD3 PPP2R5E WDR11 NUP160	3.60e-05	325	132	8	36168628
Pubmed	Defining the membrane proteome of NK cells.	KDM3A PDE3B ERAP1 LONP2 NOL9 LARP4B MOGS WDR11 PIK3R1 NUP210 EHD1 BUB1 AKAP1 GCN1 DYNC1H1	3.92e-05	1168	132	15	19946888
Pubmed	Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.	VPS13D CSMD1	4.28e-05	3	132	2	20610895
Pubmed	Searching the second hit in patients with inherited retinal dystrophies and monoallelic variants in ABCA4, USH2A and CEP290 by whole-gene targeted sequencing.	ABCA4 USH2A	4.28e-05	3	132	2	30190494
Pubmed	The Wiskott-Aldrich syndrome protein (WASP): roles in signaling and cytoskeletal organization.	WAS PIK3R1	4.28e-05	3	132	2	10358777
Pubmed	Molecular cloning and chromosomal assignment of the human homologue of the rat cGMP-inhibited phosphodiesterase 1 (PDE3A)--a gene involved in fat metabolism located at 11p 15.1.	PDE3A PDE3B	4.28e-05	3	132	2	8921398
Pubmed	Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3).	CUBN LRP2	4.28e-05	3	132	2	11717447
Pubmed	p53-dependent association between cyclin G and the B' subunit of protein phosphatase 2A.	PTPA PPP2R5E	4.28e-05	3	132	2	8887688
Pubmed	Tuberculosis risk is associated with genetic polymorphisms in the LRP2, CUBN, and VDR genes.	CUBN LRP2	4.28e-05	3	132	2	32803705
Pubmed	Cell cycle activation in lung adenocarcinoma cells by the ErbB3/phosphatidylinositol 3-kinase/Akt pathway.	ERBB3 PIK3R1	4.28e-05	3	132	2	12896906
Pubmed	Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.	EHD3 EHD1	4.28e-05	3	132	2	25686250
Pubmed	Mouse model of proximal tubule endocytic dysfunction.	CUBN LRP2	4.28e-05	3	132	2	21926402
Pubmed	Reduced proximal tubular expression of protein endocytic receptors in proteinuria is associated with urinary receptor shedding.	CUBN LRP2	4.28e-05	3	132	2	29186471
Pubmed	A naturally occurring secreted human ErbB3 receptor isoform inhibits heregulin-stimulated activation of ErbB2, ErbB3, and ErbB4.	ERBB3 PIK3R1	4.28e-05	3	132	2	11389077
Pubmed	Distinct functions of megalin and cubilin receptors in recovery of normal and nephrotic levels of filtered albumin.	CUBN LRP2	4.28e-05	3	132	2	32200668
Pubmed	Mapping of the glycoprotein 330 (Gp330) gene to mouse chromosome 2.	CHRNA1 LRP2	4.28e-05	3	132	2	8244399
Pubmed	Cubilin is an albumin binding protein important for renal tubular albumin reabsorption.	CUBN LRP2	4.28e-05	3	132	2	10811843
Pubmed	Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo.	RASA1 PIK3R1	4.28e-05	3	132	2	1314164
Pubmed	Megalin, cubilin, and Dab2 drive endocytic flux in kidney proximal tubule cells.	CUBN LRP2	4.28e-05	3	132	2	37126375
Pubmed	Regulation of Src trafficking and activation by the endocytic regulatory proteins MICAL-L1 and EHD1.	MICALL1 EHD1	4.28e-05	3	132	2	24481818
Pubmed	Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules.	CUBN LRP2	4.28e-05	3	132	2	15342463
Pubmed	Pertussis toxin promotes macrophage survival through inhibition of acid sphingomyelinase and activation of the phosphoinositide 3-kinase/protein kinase B pathway.	PIK3R1 SMPD1	4.28e-05	3	132	2	17521884
Pubmed	Differential roles of C-terminal Eps15 homology domain proteins as vesiculators and tubulators of recycling endosomes.	EHD3 EHD1	4.28e-05	3	132	2	24019528
Pubmed	Targeted disruption of cubilin reveals essential developmental roles in the structure and function of endoderm and in somite formation.	CUBN LRP2	4.28e-05	3	132	2	16787536
Pubmed	cPLA2α and EHD1 interact and regulate the vesiculation of cholesterol-rich, GPI-anchored, protein-containing endosomes.	MICALL1 EHD1	4.28e-05	3	132	2	22456504
Pubmed	Multiligand endocytosis and congenital defects: roles of cubilin, megalin and amnionless.	CUBN LRP2	4.28e-05	3	132	2	17979745
Pubmed	Knockdown of FLT4, Nup98, and Nup205 Cellular Genes Effectively Suppresses the Reproduction of Influenza Virus Strain A/WSN/1933 (H1N1) In vitro.	FLT4 NUP98	4.28e-05	3	132	2	35339191
Pubmed	Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex.	CUBN LRP2	4.28e-05	3	132	2	18400109
Pubmed	Cubilin is essential for albumin reabsorption in the renal proximal tubule.	CUBN LRP2	4.28e-05	3	132	2	20798259
Pubmed	EHD3: a protein that resides in recycling tubular and vesicular membrane structures and interacts with EHD1.	EHD3 EHD1	4.28e-05	3	132	2	12121420
Pubmed	Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats.	CUBN LRP2	4.28e-05	3	132	2	28575050
Pubmed	A two-receptor pathway for catabolism of Clara cell secretory protein in the kidney.	CUBN LRP2	4.28e-05	3	132	2	11278724
Pubmed	Cooperation of MICAL-L1, syndapin2, and phosphatidic acid in tubular recycling endosome biogenesis.	MICALL1 EHD1	4.28e-05	3	132	2	23596323
Pubmed	Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules.	CUBN LRP2	4.28e-05	3	132	2	12815097
Pubmed	Impaired endocytosis in proximal tubule from subchronic exposure to cadmium involves angiotensin II type 1 and cubilin receptors.	CUBN LRP2	4.28e-05	3	132	2	24093454
Pubmed	GM1 inhibits early signaling events mediated by PDGF receptor in cultured human glioma cells.	RASA1 PIK3R1	4.28e-05	3	132	2	10697503
Pubmed	Nup98 localizes to both nuclear and cytoplasmic sides of the nuclear pore and binds to two distinct nucleoporin subcomplexes.	NUP88 NUP98	4.28e-05	3	132	2	12589057
Pubmed	Impact of phosphodiesterases PDE3 and PDE4 on 5-hydroxytryptamine receptor4-mediated increase of cAMP in human atrial fibrillation.	PDE3A PDE3B	4.28e-05	3	132	2	32949251
Pubmed	Human parietal epithelial cells (PECs) and proteinuria in lupus nephritis: a role for ClC-5, megalin, and cubilin?	CUBN LRP2	4.28e-05	3	132	2	37594671
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	LONP2 NUP88 LARS1 PHF21A SH3BP4 EHD3 MICALL1 TBC1D32 PPP2R5E PIK3R1 BUB1 TRAPPC10 TFB2M GCN1 NUP160 DYNC1H1	4.30e-05	1321	132	16	27173435
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	BMS1 NUP98 CEP192 CEMIP2 PTPA PPP2R5E TBC1D31 PTPRF WDR11 PIK3R1 SUN2 NUP210 GCN1 SNTB1	4.78e-05	1049	132	14	27880917
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PITPNM2 PDE3B TPCN2 RASA1 TNRC6B CEP192 WDR37 SH3BP4 EHD3 UBE2J2 WDR11 NUP210 KCNN2 GREB1 CSMD1 CYP4F11 DOP1A	5.09e-05	1489	132	17	28611215
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	PTGES2 BMS1 NUP88 NUP98 TNRC6B MOGS SUN2 NUP210 NUP160	6.59e-05	457	132	9	32344865
Pubmed	Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signal.	ERBB3 CHRNA1 SLC18A3	7.81e-05	22	132	3	30870413
Pubmed	FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.	PDE3B NUP98 CEMIP2 EHD3 MOGS TRAM1 SUN2 NUP210 NUP160	7.89e-05	468	132	9	31056421
Pubmed	Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice.	PLCH1 PLCE1	8.54e-05	4	132	2	21041529
Pubmed	Interactions between EHD proteins and Rab11-FIP2: a role for EHD3 in early endosomal transport.	EHD3 EHD1	8.54e-05	4	132	2	16251358
Pubmed	C-terminal EH-domain-containing proteins: consensus for a role in endocytic trafficking, EH?	EHD3 EHD1	8.54e-05	4	132	2	16155252
Cytoband	5q13.1	PIK3R1 OCLN	1.22e-04	6	132	2	5q13.1
GeneFamily	Nucleoporins	NUP88 NUP98 NUP210 NUP160	1.86e-05	32	90	4	1051
Coexpression	SEAVEY_EPITHELIOID_HEMANGIOENDOTHELIOMA	PDE3A ABCA4 CUBN EDN1 ANKRD33 KCNN2	7.42e-06	93	131	6	M42516
Coexpression	GSE17721_LPS_VS_POLYIC_6H_BMDC_DN	KDM3A WAS MBOAT1 NUP88 PHKA2 PTPA SUN2 TRAPPC10	7.47e-06	199	131	8	M3809
Coexpression	GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_DN	DAPK1 CEP192 GPR146 LARP4B PTPA SUN2 PCSK6 DYNC1H1	7.75e-06	200	131	8	M7143
ToppCell	RSV-Healthy-0\|RSV / Virus stimulation, Condition and Cluster	PDE3B OAS3 WDR11 SUN2 EHD1 TRAPPC10 NUP160	1.13e-06	180	132	7	974044056e2f7e909cb11c6f6ca89e58bf95f7e5
ToppCell	RSV-Healthy-0\|Healthy / Virus stimulation, Condition and Cluster	PDE3B OAS3 WDR11 SUN2 EHD1 TRAPPC10 NUP160	1.13e-06	180	132	7	703a1d0f9536af94d56757eb01221878d7b7fe61
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 OTOGL LRP2 CSMD1 PLCH1 USH2A PLCE1	1.31e-06	184	132	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 OTOGL LRP2 CSMD1 PLCH1 USH2A PLCE1	1.31e-06	184	132	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 OTOGL LRP2 CSMD1 PLCH1 USH2A PLCE1	1.31e-06	184	132	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PITPNM2 FLT4 OAS3 NRROS GPR146 OCLN DYNC1H1	2.28e-06	200	132	7	89821a264e872ed53e08e9d3609d5cc5c314503e
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / Treatment groups by lineage, cell group, cell type	PITPNM2 PDE3B FLT4 OAS3 NRROS GPR146 OCLN	2.28e-06	200	132	7	b1fadb2b5e37e0f51e079d8409c2647eef68dc3b
ToppCell	10x5'-Lung-Lymphocytic_NK-NK_CD56bright_CD16-\|Lung / Manually curated celltypes from each tissue	PITPNM2 CDHR1 SPEG CEMIP2 GALNT17 PIK3R1	8.04e-06	159	132	6	595643e9433265308e5aab7f906229025701cf6a
ToppCell	BAL-Mild-cDC_4\|Mild / Compartment, Disease Groups and Clusters	MUC16 CEP192 STARD9 EHD1 TFB2M OCLN	1.58e-05	179	132	6	68511e87b12b8253de7771e5ccfc5869248b8450
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC2A9 CUBN LRP2 GREB1 CSMD1 D2HGDH	1.96e-05	186	132	6	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ERBB3 FCGBP PTPRF NUP210 LRP2 PLCH1	1.96e-05	186	132	6	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ERBB3 GALNT17 LRRN2 GREB1 CSMD1 PLCE1	2.02e-05	187	132	6	6f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 PDE3B FLT4 NRROS EHD3 GPR146	2.21e-05	190	132	6	a3c6eec6df052105ab78b7e3c78f94218d5912eb
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ERBB3 PTPRF NUP210 LRP2 OCLN PLCH1	2.34e-05	192	132	6	1aa5e4d9b32013a3f272561dcb8377f6805706df
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ERBB3 PTPRF NUP210 LRP2 OCLN PLCH1	2.41e-05	193	132	6	ab78fb1603ea6f720ba2d30148fe65dccf271fe1
ToppCell	PCW_07-8.5-Epithelial\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ERBB3 PTPRF NUP210 LRP2 OCLN PLCH1	2.48e-05	194	132	6	f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ERBB3 PTPRF NUP210 LRP2 OCLN PLCH1	2.63e-05	196	132	6	7b17d47b7758d8ccf9dbefd097aeb553791a1eed
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD56bright\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLT4 CDHR1 TBC1D31 EBI3 NUP210 RPUSD2	2.63e-05	196	132	6	bbdc92ec2e95ed7d782df0c72d94f9a9d9439bf0
ToppCell	Bronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Mucous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ERBB3 MUC16 ERN2 TAS2R10 FCGBP OTOGL	2.86e-05	199	132	6	eb2d1b7e875c5bf833e7a80b43282e12893c34e9
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PITPNM2 FLT4 OAS3 NRROS GPR146 OCLN	2.94e-05	200	132	6	bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PITPNM2 PDE3B FLT4 NRROS GPR146 OCLN	2.94e-05	200	132	6	b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PITPNM2 PDE3B FLT4 NRROS GPR146 OCLN	2.94e-05	200	132	6	a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PITPNM2 PDE3B FLT4 NRROS GPR146 OCLN	2.94e-05	200	132	6	89a6da2bdedc6b1ad0675c8753bf2b763a99af6a
ToppCell	LPS_IL1RA_TNF-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PITPNM2 PDE3B FLT4 NRROS GPR146 OCLN	2.94e-05	200	132	6	d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Gabra5)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PAPPA2 ESX1 OTOGL FCRLB	6.24e-05	72	132	4	480653f8bd0ef118cb8d541103692e3ec8a1b58d
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	RASA1 NUP88 OAS3	7.66e-05	28	132	3	456cf2e0a6ea59c279efc77a1d02e5572196cb6b
ToppCell	Striatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat-Inhibitory_Neuron.Gad1Gad2-Chat-Slc17a8.Chat_(cholinergic_interneuron)\|Striatum / BrainAtlas - Mouse McCarroll V32	CUBN ERN2 SLC18A3 WDR87	7.71e-05	76	132	4	3073a8ace46ad18bddd22ec8f3a1b59ee2fd989d
ToppCell	Striatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat-Inhibitory_Neuron.Gad1Gad2-Chat-Slc17a8.Chat_(cholinergic_interneuron)-\|Striatum / BrainAtlas - Mouse McCarroll V32	CUBN ERN2 SLC18A3 WDR87	7.71e-05	76	132	4	3f5865b9cb6648b88eb873018e513c5efb457ae5
ToppCell	Striatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Chat\|Striatum / BrainAtlas - Mouse McCarroll V32	CUBN ERN2 SLC18A3 WDR87	7.71e-05	76	132	4	041a8984b3ae4bb03ae6db8234c1333ac73098fa
ToppCell	severe_COVID-19-CD8+_T_naive\|World / disease group, cell group and cell class (v2)	PDE3B SPEG MYRFL DCT PLCE1	9.31e-05	153	132	5	422483445af49c277fc8962d76a46ffafd872422
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Nefm_(dSPN)-\|Striatum / BrainAtlas - Mouse McCarroll V32	CDHR1 VWA7 CHRNA1 KLHL14	9.42e-05	80	132	4	cb60461818f0900964d2a14c7f8462e7f37b3dff
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Nefm_(dSPN)\|Striatum / BrainAtlas - Mouse McCarroll V32	CDHR1 VWA7 CHRNA1 KLHL14	9.42e-05	80	132	4	27cc5ea77983fb0604545a0ff818eede8ba72b82
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MUC16 MSLNL LRP2 KLHL14 PLCE1	1.02e-04	156	132	5	574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCell	PND07-28-samps-Mesenchymal-Mesothelial-Mesothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MUC16 MSLNL LRP2 KLHL14 PLCE1	1.02e-04	156	132	5	605d95a900e1443d3f6aae163ef2e893d3293203
ToppCell	Striatum-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Striatum / BrainAtlas - Mouse McCarroll V32	CUBN ERN2 SLC18A3 WDR87	1.14e-04	84	132	4	9417fffe0ba79f5851920258dcd0f6c09218be13
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ERBB3 FLT4 CDHR1 DAPK1 STIL	1.18e-04	161	132	5	58381131e651744b5141b202f9d6063f55432db5
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ERBB3 DCT LRP2 CSMD1 SNTB1	1.29e-04	164	132	5	3caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PITPNM2 PDE3A EHD3 PCSK6 PLCH1	1.33e-04	165	132	5	6799a6580c667738995cceb31cbf1c7fbdc4ff84
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PITPNM2 PDE3A EHD3 PCSK6 PLCH1	1.33e-04	165	132	5	8329d780f244bc31344443b29e5a00529a016662
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231\|Adult / Lineage, Cell type, age group and donor	FLT4 GPR146 STARD9 KCNN2 MMP11	1.40e-04	167	132	5	5af9127bae05768a5164d5708a4ad37edca99324
ToppCell	Children_(3_yrs)-Immune-enucleated_erythrocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	WAS ERN2 OTOGL PCSK6 EHD1	1.44e-04	168	132	5	8f0c4dfad9f6fed9dcc31795abfe77758ceb46a1
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STIL VWA7 FANCG HMGXB3 AKAP1	1.44e-04	168	132	5	b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	SH3BP4 EHD3 MICALL1 TMEM267 PLCE1	1.48e-04	169	132	5	29db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	SH3BP4 EHD3 MICALL1 TMEM267 PLCE1	1.48e-04	169	132	5	b1611e61f635f8f9b87250e026ad30999cbee041
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUBN OTOGL LRP2 PLCH1 USH2A	1.48e-04	169	132	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	NS-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	STIL PCSK6 CFAP206 SLC38A8 PLCE1	1.52e-04	170	132	5	f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE3A ERAP1 EDN1 CEMIP2 MICALL1	1.52e-04	170	132	5	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	facs-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE3A ERAP1 EDN1 CEMIP2 MICALL1	1.52e-04	170	132	5	67d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCell	367C-Myeloid-Monocyte-CD16+_Monocyte\|Monocyte / Donor, Lineage, Cell class and subclass (all cells)	KDM3A B3GLCT ECM1 KLHL14 GCN1	1.61e-04	172	132	5	fb8ab2576b5c38db63573a3bf46b8d9d634c4999
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ERBB3 PGLYRP4 MUC16 ERN2 FCGBP	1.65e-04	173	132	5	d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUBN OTOGL LRP2 PLCH1 USH2A	1.65e-04	173	132	5	66f37c1437705734b20601656fa4aa1d92ca30be
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUBN OTOGL LRP2 PLCH1 USH2A	1.65e-04	173	132	5	649b08a409095592cccf31883be69c754411280d
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGLYRP4 BCORL1 CEMIP2 ABHD5 BUB1	1.70e-04	174	132	5	9d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCell	facs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PGLYRP4 BCORL1 CEMIP2 ABHD5 BUB1	1.70e-04	174	132	5	53cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PGLYRP4 FCGBP MOGS PLCH1 SNTB1	1.75e-04	175	132	5	dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERBB3 PIGZ NUP210 LRP2 OCLN	1.75e-04	175	132	5	6759d200a133034756de9cdf2d5daceca927aac9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC2A9 CUBN LRP2 GREB1 CSMD1	1.84e-04	177	132	5	2f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell	cellseq2-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MSC BCORL1 ECM1 STARD9 FCRLB	1.84e-04	177	132	5	68263456a3c93cd195b321b309ff59e156d732fe
ToppCell	cellseq2-Mesenchymal-Myocytic-Myocytic_1\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MSC BCORL1 ECM1 STARD9 FCRLB	1.84e-04	177	132	5	e415e448c37adc102d766235e9953dec32c021f1
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAPPA2 MUC16 ECM1 LRP2 PLCE1	1.89e-04	178	132	5	bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAPPA2 MUC16 ECM1 LRP2 PLCE1	1.89e-04	178	132	5	c413861148129be1ee94f2ceb5999840217eebe5
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STIL BUB1 CCDC180 SLC38A8 PLCE1	1.94e-04	179	132	5	d15182c668d7c37be8214cad9f1fe35d1409c9a1
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE3A ABCA4 EDN1 CEMIP2 OCLN	1.94e-04	179	132	5	a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STIL BUB1 CCDC180 SLC38A8 PLCE1	1.94e-04	179	132	5	e22a275a7c0ed19113c833a75d6c49fcc19aa13a
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FLT4 ABCA4 GPR146 PCSK6 KLHL14	1.94e-04	179	132	5	ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-BEST2+_Goblet_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDHR1 ERN2 PIGZ FCGBP PTPRF	1.94e-04	179	132	5	c833ded1f9e87be2ba2037820d92a389560b711c
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYRFL ECM1 GREB1 PLCH1 PLCE1	1.94e-04	179	132	5	d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FLT4 ABCA4 GPR146 PCSK6 KLHL14	1.94e-04	179	132	5	35fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCell	368C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ERBB3 TPCN2 CUBN SNTB1 UEVLD	1.99e-04	180	132	5	eb5a57604c7f2ad256c300085dbf5069d0ae1ad0
ToppCell	368C-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ERBB3 TPCN2 CUBN SNTB1 UEVLD	1.99e-04	180	132	5	ddba4dc3bbcfe4e4a22400be73bbc62d3ff27d3c
ToppCell	368C-Endothelial_cells-Endothelial-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	EDN1 CEMIP2 GPR146 PCSK6 KCNN2	1.99e-04	180	132	5	8ab16a0b9053bffc07b569a4f9e71749f56dde7e
ToppCell	368C-Endothelial_cells-Endothelial-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	EDN1 CEMIP2 GPR146 PCSK6 KCNN2	1.99e-04	180	132	5	394cd465b88429b70eebb2957480dffcbc51cfe7
ToppCell	facs-GAT-Fat-3m-Epithelial-epithelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDH1B LRP2 CFAP206 OCLN PLCH1	2.04e-04	181	132	5	e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCell	facs-GAT-Fat-3m-Epithelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDH1B LRP2 CFAP206 OCLN PLCH1	2.04e-04	181	132	5	11cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype\|TCGA-Lung / Sample_Type by Project: Shred V9	ERBB3 TRAM1 OCLN PLCH1 SNTB1	2.04e-04	181	132	5	c783c2ecca7ab8e07646fa92dc7d436d24939d03
ToppCell	facs-GAT-Fat-3m-Epithelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDH1B LRP2 CFAP206 OCLN PLCH1	2.04e-04	181	132	5	5ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC2A9 CUBN LRP2 GREB1 CSMD1	2.09e-04	182	132	5	e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC2A9 CUBN LRP2 GREB1 CSMD1	2.09e-04	182	132	5	4a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ENGASE MYRFL ECM1 PLCH1 PLCE1	2.09e-04	182	132	5	08aff7112c9dac0ef5540300516a604782b21169
ToppCell	Pericytes-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	VN1R2 PDE3A SPEG MYRFL OTOGL	2.09e-04	182	132	5	46c213597445b1f4f09dc367f27702d24b201daf
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC2A9 CUBN LRP2 GREB1 CSMD1	2.09e-04	182	132	5	57bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN LRP2 GREB1 CSMD1 USH2A	2.15e-04	183	132	5	d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCell	facs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l14\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TPCN2 PEX7 CUBN FCGBP PTPRF	2.15e-04	183	132	5	6e5b39c0170d62eb7fdd411dcfff51ed176573d0
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PAPPA2 MUC16 ECM1 LRP2 PLCE1	2.15e-04	183	132	5	274f274cf60daa30d6a4cd603a3af7823bfb8016
ToppCell	facs-SCAT-Fat-3m-Lymphocytic-T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE3B EHD3 SUN2 NUP210 SNTB1	2.20e-04	184	132	5	cdacb61878e0824b8416bf365d89965797208359
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	RASA1 PHKA2 FANCG TBC1D31 WDR11	2.20e-04	184	132	5	2c2125b8030af83f7a6d59a7102d4de8e0ac1988
ToppCell	Control-Epithelial_cells-Airway_goblet\|Control / group, cell type (main and fine annotations)	ERBB3 MUC16 ERN2 FCGBP PCSK6	2.20e-04	184	132	5	d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell	facs-Heart-LA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 CDHR1 EDN1 CEMIP2 OCLN	2.26e-04	185	132	5	1ecfca049c0c1110fd1b2256db7cb7abda6afb04
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSC CHRNA1 LRP2 GREB1 WDR77	2.26e-04	185	132	5	5414a66169c39d09a67b1050aad5e61f46b3749a
ToppCell	facs-Heart-LA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 CDHR1 EDN1 CEMIP2 OCLN	2.26e-04	185	132	5	b6df1412b579d40ed5df806f9c54bd1fbb9a1e15
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-Aerocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PITPNM2 FLT4 GPR146 KCNN2 OCLN	2.26e-04	185	132	5	7b3d30a54bec66ca6b0209c86448f4fff97ed75c
ToppCell	COPD-Lymphoid-B\|COPD / Disease state, Lineage and Cell class	NUP88 TNRC6B CEMIP2 EHD3 KLHL14	2.26e-04	185	132	5	925e79c35c381dd44ec5fb921dca09ce43140135
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYRFL ECM1 KLHL14 PLCH1 PLCE1	2.26e-04	185	132	5	f4ac62009c0ad3346e71b809e17727303c4df153
ToppCell	COPD-Lymphoid-B\|World / Disease state, Lineage and Cell class	NUP88 TNRC6B CEMIP2 EHD3 KLHL14	2.26e-04	185	132	5	22891ed75e25ef30dfa541cb82d85e08ce07e7d9
ToppCell	Control-Endothelial-Endothelial-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 PDE3B FLT4 EHD3 SNTB1	2.37e-04	187	132	5	ea9d34bcd3bd1f36745846309ede349773de501a
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PDE3B TNRC6B CEMIP2 PPP2R5E PIK3R1	2.37e-04	187	132	5	e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCell	Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Col25a1_(Neuron.Gad1Gad2.Col25a1)\|Thalamus / BrainAtlas - Mouse McCarroll V32	ANKRD33 TNN BUB1	2.43e-04	41	132	3	cafe7d76e4e3fb609b38a3fbd21f51709c3fd4b6
ToppCell	Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Col25a1_(Neuron.Gad1Gad2.Col25a1)--\|Thalamus / BrainAtlas - Mouse McCarroll V32	ANKRD33 TNN BUB1	2.43e-04	41	132	3	42012881e101e046d23dde9720235b5f76abc357
ToppCell	Thalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Col25a1_(Neuron.Gad1Gad2.Col25a1)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	ANKRD33 TNN BUB1	2.43e-04	41	132	3	be612f96ec898e39cae87722bffd2016765911d5
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3-Excitatory_Neuron.Slc17a7.Pvrl3-St18_(Lateral_CA3_Principal_cells)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	OAS3 FCGBP SLC38A8	2.43e-04	41	132	3	083d2aab96ba9449797f955507c4a1be51ac5c8d
Drug	geldanamycin; Down 200; 1uM; HL60; HT_HG-U133A	SLC2A9 MYOF VPS13D MOGS SUN2 TRAPPC10 RPUSD2 TFB2M AKAP1 WDR77	1.76e-07	194	130	10	1169_DN
Drug	Cyanocobalamin [68-19-9]; Down 200; 3uM; MCF7; HT_HG-U133A	WAS OAS3 ERN2 LARP4B VPS13D PIK3R1 GREB1 DOP1A	1.49e-05	192	130	8	3252_DN
Drug	Dipyridamole [58-32-2]; Down 200; 8uM; HL60; HG-U133A	RASA1 LONP2 BCORL1 PHKA2 MYOF VPS13D TMEM267 KCNN2	1.67e-05	195	130	8	2017_DN
Drug	haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A	FLT4 ERN2 PIGZ MICALL1 MYOF NUP210 EHD1 DOP1A	1.67e-05	195	130	8	5241_DN
Drug	Mafenide hydrochloride [138-37-4]; Down 200; 18uM; PC3; HT_HG-U133A	NUP98 ERN2 EHD3 MYOF PTPA NUP210 HMGXB3 AKAP1	1.80e-05	197	130	8	2124_DN
Drug	Dinoprost trometamol [38362-01-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A	ERAP1 LONP2 OAS3 VPS13D SUN2 PCSK6 SMPD1 PLCH1	1.80e-05	197	130	8	3308_DN
Drug	Cyclacillin [3485-14-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A	PGLYRP4 WAS ERAP1 SPEG ERN2 PCSK6 LRP2 SMPD1	1.86e-05	198	130	8	4358_UP
Drug	Acenocoumarol [152-72-7]; Down 200; 11.4uM; PC3; HT_HG-U133A	ERN2 ECM1 LARP4B VPS13D PIK3R1 BUB1 PLCH1 NUP160	1.86e-05	198	130	8	5878_DN
Drug	Mometasone furoate [83919-23-7]; Down 200; 7.6uM; MCF7; HT_HG-U133A	MICALL1 LARP4B PCSK6 EHD1 LRP2 SMPD1 GREB1 PLCH1	1.93e-05	199	130	8	5541_DN
Drug	Inocor (TN)	PDE3A PDE3B	3.24e-05	2	130	2	CID000656683
Drug	RS-1893	PDE3A PDE3B	3.24e-05	2	130	2	CID000128386
Drug	tautomycin	PDE3A PDE3B PHKA2 PTPA PPP2R5E AKAP1	6.03e-05	118	130	6	CID000440646
Drug	papaverine	PDE3A PDE3B EDN1 SMPD1 PLCH1 TDP1 PLCE1	6.96e-05	176	130	7	CID000004680
Drug	Digoxigenin [1672-46-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A	ENGASE PDE3B WDR37 LARP4B TBC1D31 PIK3R1 RPUSD2	7.74e-05	179	130	7	5640_DN
Drug	Methotrexate [59-05-2]; Down 200; 8.8uM; MCF7; HT_HG-U133A	PDE3B NAA60 ERN2 EHD3 EHD1 BUB1 PLCH1	8.29e-05	181	130	7	5419_DN
Drug	Fenbendazole [43210-67-9]; Up 200; 13.4uM; PC3; HT_HG-U133A	PDE3B ERAP1 EDN1 LARP4B LRRN2 SMPD1 CYP4F11	9.51e-05	185	130	7	4542_UP
Drug	SureCN4406168	PDE3A PDE3B	9.67e-05	3	130	2	CID011502028
Drug	SureCN4395097	PDE3A PDE3B	9.67e-05	3	130	2	CID011610011
Drug	SureCN4401117	PDE3A PDE3B	9.67e-05	3	130	2	CID011718172
Drug	SureCN4402206	PDE3A PDE3B	9.67e-05	3	130	2	CID011516917
Drug	WIN 62582	PDE3A PDE3B	9.67e-05	3	130	2	CID005487388
Drug	SureCN4397066	PDE3A PDE3B	9.67e-05	3	130	2	CID011538627
Drug	SureCN4401121	PDE3A PDE3B	9.67e-05	3	130	2	CID011611819
Drug	SureCN4404748	PDE3A PDE3B	9.67e-05	3	130	2	CID011502895
Drug	SureCN4411688	PDE3A PDE3B	9.67e-05	3	130	2	CID011523192
Drug	SureCN4405038	PDE3A PDE3B	9.67e-05	3	130	2	CID011546172
Drug	SureCN4405912	PDE3A PDE3B	9.67e-05	3	130	2	CID011682920
Drug	pelrinone	PDE3A PDE3B	9.67e-05	3	130	2	CID000055919
Drug	SureCN4398032	PDE3A PDE3B	9.67e-05	3	130	2	CID011532088
Drug	SureCN4406373	PDE3A PDE3B	9.67e-05	3	130	2	CID011711104
Drug	SureCN4394894	PDE3A PDE3B	9.67e-05	3	130	2	CID011711103
Drug	SureCN5995113	PDE3A PDE3B	9.67e-05	3	130	2	CID011640499
Drug	CHEMBL219123	PDE3A PDE3B	9.67e-05	3	130	2	CID016102624
Drug	germitrine	PDE3A PDE3B	9.67e-05	3	130	2	CID000011217
Drug	SureCN4411840	PDE3A PDE3B	9.67e-05	3	130	2	CID011567407
Drug	SureCN4401113	PDE3A PDE3B	9.67e-05	3	130	2	CID011544858
Drug	SureCN4405883	PDE3A PDE3B	9.67e-05	3	130	2	CID011516351
Drug	SureCN4407211	PDE3A PDE3B	9.67e-05	3	130	2	CID011553351
Drug	SureCN4401096	PDE3A PDE3B	9.67e-05	3	130	2	CID011710801
Drug	Amethopterin (R,S) [59-05-2]; Down 200; 8.8uM; MCF7; HT_HG-U133A	LONP2 NUP98 STIL PHKA2 LARP4B BUB1 GREB1	9.84e-05	186	130	7	5000_DN
Drug	Thioguanosine [85-31-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A	BCORL1 NUP98 ERN2 VPS13D TBC1D31 BUB1 TRAPPC10	1.12e-04	190	130	7	2619_DN
Drug	17-AAG; Down 200; 1uM; PC3; HT_HG-U133A	KDM3A ERAP1 BCORL1 PTPA PIK3R1 NUP210 EHD1	1.16e-04	191	130	7	1225_DN
Drug	Tetrahydrozoline hydrochloride [522-48-5]; Down 200; 16.8uM; HL60; HT_HG-U133A	FLT4 PEX7 PCSK6 RPUSD2 AKAP1 NUP160 SNTB1	1.20e-04	192	130	7	2507_DN
Drug	Carisoprodol [78-44-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A	PDE3B LONP2 BCORL1 MYOF LARP4B LRP2 KCNN2	1.24e-04	193	130	7	3251_UP
Drug	5213008; Up 200; 18uM; MCF7; HT_HG-U133A_EA	WAS BCORL1 ERN2 LARP4B BUB1 GREB1 PLCH1	1.28e-04	194	130	7	898_UP
Drug	Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A	PGLYRP4 WAS VPS13D EHD1 LRP2 GREB1 PLCH1	1.28e-04	194	130	7	3422_UP
Drug	Methoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; MCF7; HT_HG-U133A	ERN2 PHKA2 MYOF TAS2R10 PCSK6 EHD1 AKAP1	1.28e-04	194	130	7	2893_UP
Drug	Procyclidine hydrochloride [1508-76-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A	PDE3B SPEG OAS3 MICALL1 VPS13D EHD1 GREB1	1.32e-04	195	130	7	4817_UP
Drug	Tamoxifen citrate [54965-24-1]; Down 200; 7uM; HL60; HG-U133A	PDE3B RASA1 MICALL1 LARP4B PTPA PIK3R1 DOP1A	1.32e-04	195	130	7	1366_DN
Drug	radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; HL60; HT_HG-U133A	NAA60 ERN2 MYOF LARP4B PTPA MOGS RPUSD2	1.32e-04	195	130	7	1160_DN
Drug	Berberine chloride [633-65-8]; Down 200; 10.8uM; PC3; HT_HG-U133A	PEX7 WDR37 MICALL1 MOGS PIK3R1 NUP210 SMPD1	1.36e-04	196	130	7	7143_DN
Drug	Hesperetin [520-33-2]; Down 200; 13.2uM; HL60; HG-U133A	PAPPA2 MYOF VPS13D ABHD5 RPUSD2 AKAP1 WDR77	1.36e-04	196	130	7	2031_DN
Drug	Yohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; MCF7; HT_HG-U133A	PDE3B WAS ERAP1 VPS13D PCSK6 EHD1 PLCH1	1.36e-04	196	130	7	6777_DN
Drug	Mafenide hydrochloride [138-37-4]; Down 200; 18uM; MCF7; HT_HG-U133A	ERN2 LARP4B BUB1 LRP2 RPUSD2 HMGXB3 NUP160	1.36e-04	196	130	7	5499_DN
Drug	Ethamsylate [2624-44-4]; Up 200; 15.2uM; MCF7; HT_HG-U133A	BCORL1 OAS3 MYOF VPS13D SUN2 EHD1 GREB1	1.36e-04	196	130	7	7335_UP
Drug	Ganciclovir [82410-32-0]; Up 200; 15.6uM; MCF7; HT_HG-U133A	MSC ERAP1 EDN1 MYOF PCSK6 MMP11 PLCE1	1.36e-04	196	130	7	3368_UP
Drug	Mesoridazine besylate [32672-69-8]; Down 200; 7.4uM; PC3; HT_HG-U133A	ENGASE TNRC6B ERN2 MYOF NUP210 RPUSD2 DOP1A	1.36e-04	196	130	7	7256_DN
Drug	HQL-79	PTGES2 PDE3A PDE3B	1.39e-04	18	130	3	CID006540277
Drug	Sulfamethizole [144-82-1]; Down 200; 14.8uM; HL60; HT_HG-U133A	FLT4 ERN2 MICALL1 MYOF VPS13D TAS2R10 PCSK6	1.41e-04	197	130	7	2536_DN
Drug	Scopolamin-N-oxide hydrobromide [6106-81-6]; Down 200; 10uM; MCF7; HT_HG-U133A	PDE3B FLT4 WAS ERN2 MICALL1 VPS13D LRP2	1.41e-04	197	130	7	5436_DN
Drug	Alclometasone dipropionate [667634-13-2]; Down 200; 7.6uM; MCF7; HT_HG-U133A	PTGES2 ERN2 LARP4B VPS13D TBC1D31 BUB1 NUP160	1.41e-04	197	130	7	6229_DN
Drug	Leflunomide [75706-12-6]; Down 200; 14.8uM; PC3; HT_HG-U133A	WAS LONP2 OAS3 CEMIP2 VPS13D NUP210 AKAP1	1.41e-04	197	130	7	5884_DN
Drug	Rapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A	ENGASE SLC2A9 NAA60 PIK3R1 NUP210 RPUSD2 DOP1A	1.41e-04	197	130	7	1148_DN
Drug	LY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A	FLT4 NUP98 CEMIP2 TRAPPC10 HMGXB3 AKAP1 NUP160	1.41e-04	197	130	7	6935_DN
Drug	Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A	FLT4 ERAP1 BCORL1 ERN2 MYOF KCNN2 TRAPPC10	1.41e-04	197	130	7	2324_DN
Drug	Deoxycorticosterone [64-85-7]; Down 200; 12.2uM; PC3; HT_HG-U133A	FLT4 SPEG PTPRF PIK3R1 BUB1 PLCH1 AKAP1	1.41e-04	197	130	7	6758_DN
Drug	Adiphenine hydrochloride [50-42-0]; Down 200; 11.4uM; MCF7; HT_HG-U133A	WAS LONP2 TNRC6B NUP210 EHD1 SMPD1 PLCH1	1.41e-04	197	130	7	7037_DN
Drug	gentamicin	ENGASE EDN1 LRP2 SMPD1 PLCH1 SNTB1 PLCE1	1.45e-04	198	130	7	CID000003467
Drug	Ethambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; PC3; HG-U133A	PEX7 MICALL1 VPS13D NUP210 RPUSD2 TFB2M AKAP1	1.45e-04	198	130	7	1900_DN
Drug	5253409; Down 200; 17uM; MCF7; HT_HG-U133A_EA	PDE3B PEX7 TNRC6B PIK3R1 NUP210 EHD1 TRAPPC10	1.45e-04	198	130	7	961_DN
Drug	Bufexamac [2438-72-4]; Down 200; 18uM; MCF7; HT_HG-U133A	CEMIP2 EHD3 VPS13D BUB1 LRP2 HMGXB3 AKAP1	1.45e-04	198	130	7	5515_DN
Drug	Ketoprofen [22071-15-4]; Up 200; 15.8uM; MCF7; HT_HG-U133A	PAPPA2 EDN1 TAS2R10 PCSK6 LRRN2 PLCH1 AKAP1	1.45e-04	198	130	7	4751_UP
Drug	(S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; MCF7; HT_HG-U133A	PAPPA2 MSC DAPK1 DCT VPS13D LRP2 SNTB1	1.50e-04	199	130	7	6444_UP
Drug	ICI 182,780; Down 200; 1uM; PC3; HT_HG-U133A	WAS SPEG PEX7 EHD3 PHKA2 MYOF VPS13D	1.50e-04	199	130	7	1205_DN
Drug	(+/-)-blebbistatin; Down 200; 17uM; MCF7; HT_HG-U133A_EA	PDE3B BCORL1 TNRC6B PIGZ EHD1 SMPD1 PLCH1	1.50e-04	199	130	7	954_DN
Drug	Estriol [50-27-1]; Down 200; 13.8uM; PC3; HT_HG-U133A	NUP98 ECM1 VPS13D PTPRF SUN2 NUP210 AKAP1	1.50e-04	199	130	7	5866_DN
Drug	Cefmetazole sodium salt [56796-39-5]; Up 200; 8.2uM; MCF7; HT_HG-U133A	MSC SLC2A9 ERAP1 ECM1 VPS13D EHD1 GREB1	1.54e-04	200	130	7	6086_UP
Drug	Ascorbic acid [50-81-7]; Down 200; 22.4uM; HL60; HG-U133A	PAPPA2 ENGASE BCORL1 PHF21A LARP4B ERAL1 AKAP1	1.54e-04	200	130	7	1610_DN
Drug	Repaglinide [135062-02-1]; Down 200; 8.8uM; PC3; HT_HG-U133A	NUP98 OAS3 ERN2 MYOF LARP4B VPS13D NUP160	1.54e-04	200	130	7	5862_DN
Drug	AC1L1O6Q	ERBB3 PTPRF PIK3R1 PLCH1 AKAP1 PLCE1	1.61e-04	141	130	6	CID000058035
Drug	Melphalan	MBOAT1 TNRC6B EDN1 PHF21A FANCG PIK3R1 CFAP206 SNTB1	1.91e-04	276	130	8	ctd:D008558
Drug	3,5-triiodobenzoic acid	DCT PTPA	1.93e-04	4	130	2	CID000016857
Drug	R 80122	PDE3A PDE3B	1.93e-04	4	130	2	CID009571043
Drug	isomazole	PDE3A PDE3B	1.93e-04	4	130	2	CID000055689
Drug	UK-1745	PDE3A PDE3B	1.93e-04	4	130	2	CID003035852
Drug	nanterinone	PDE3A PDE3B	1.93e-04	4	130	2	CID000071305
Drug	olprinone	PDE3A PDE3B EDN1	1.93e-04	20	130	3	CID000004593
Drug	milrinone	PDE3A PDE3B SMPD1 PLCH1 TDP1 PLCE1	2.25e-04	150	130	6	CID000004197
Disease	cancer antigen 125 measurement	MUC16 MSLNL D2HGDH	8.71e-06	10	125	3	EFO_0010603
Disease	cerebellum cortex volume change measurement, age at assessment	PIK3R1 CSMD1 PLCH1	1.80e-04	26	125	3	EFO_0008007, EFO_0021497
Disease	Stomach Neoplasms	ERBB3 ECM1 PTPA FCGBP PTPRF EBI3 PLCE1	2.83e-04	297	125	7	C0038356
Disease	Malignant neoplasm of stomach	ERBB3 ECM1 PTPA FCGBP PTPRF EBI3 PLCE1	3.00e-04	300	125	7	C0024623
Disease	hypertension	PDE3A B3GLCT ERAP1 OAS3 NUP160 SNTB1 PLCE1	3.45e-04	307	125	7	EFO_0000537
Disease	asthma, allergic disease	ERBB3 NRROS SH3BP4 D2HGDH	3.61e-04	79	125	4	MONDO_0004979, MONDO_0005271
Disease	Pena-Shokeir syndrome type I	NUP88 SLC18A3	4.90e-04	8	125	2	C1276035
Disease	blood cobalt measurement	SLC2A9 MUC16 POM121L12 USH2A	9.13e-04	101	125	4	EFO_0007577
Disease	phenylacetylglutamine measurement	B3GLCT SNTB1	1.14e-03	12	125	2	EFO_0021013
Disease	triacylglycerol 52:1 measurement	SLC22A15 CSMD1	1.57e-03	14	125	2	EFO_0010413
Disease	creatinine measurement, glomerular filtration rate	WDR37 LARP4B PIK3R1 LRP2	1.57e-03	117	125	4	EFO_0004518, EFO_0005208
Disease	Hereditary Diffuse Gastric Cancer	ECM1 PTPA FCGBP PTPRF EBI3 PLCE1	1.59e-03	293	125	6	C1708349
Disease	aspartate aminotransferase measurement	ERBB3 PDE3A ABCA4 CUBN WDR11 PIK3R1 HMGXB3 CSMD1 GCN1 NUP160 PLCE1	1.64e-03	904	125	11	EFO_0004736
Disease	Proteinuria	CUBN LRP2	1.80e-03	15	125	2	HP_0000093
Disease	household income	PITPNM2 PTGES2 ERBB3 PTPRF PIK3R1 LRRN2	1.92e-03	304	125	6	EFO_0009695
Disease	prostate carcinoma, type 2 diabetes mellitus	TPCN2 TNRC6B LRRN2	2.03e-03	59	125	3	EFO_0001663, MONDO_0005148
Disease	Cardiovascular Abnormalities	WDR37 EDN1	2.05e-03	16	125	2	C0243050
Disease	Disorder of eye	B3GLCT ABCA4 CDHR1 PEX7 USH2A	2.13e-03	212	125	5	C0015397
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	KDM3A ERBB3 PHF21A CEMIP2 ABHD5 PTPRF IQCJ POM121L12 LRRN2 USH2A	2.21e-03	801	125	10	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	serum metabolite measurement	PDE3A SLC2A9 ERAP1 PHF21A SH3BP4 LARP4B MROH1 CSMD1 CCDC180 D2HGDH SNTB1	2.31e-03	945	125	11	EFO_0005653
Disease	neck circumference	ANKRD33 GALNT17	2.90e-03	19	125	2	EFO_0011043
Disease	portal hypertension (implicated_via_orthology)	EDN1 PIK3R1	2.90e-03	19	125	2	DOID:10762 (implicated_via_orthology)
Disease	response to methotrexate, neurotoxicity	MBOAT1 DCT	2.90e-03	19	125	2	EFO_0011057, GO_0031427
Disease	urinary microalbumin measurement	CUBN KCNN2	3.22e-03	20	125	2	EFO_0010967
Disease	triacylglycerol 46:1 measurement	SLC22A15 CSMD1	3.22e-03	20	125	2	EFO_0010401
Disease	anorexia nervosa	ERBB3 WDR11 LRP2	3.30e-03	70	125	3	MONDO_0005351
Disease	chronic kidney disease	ABCA4 SLC2A9 SH3BP4 LARP4B LRP2	3.32e-03	235	125	5	EFO_0003884
Disease	creatinine measurement	TPCN2 SLC2A9 MBOAT1 SPEG TNRC6B CUBN EDN1 LARP4B PIK3R1 LRP2 MMP11	3.42e-03	995	125	11	EFO_0004518
Disease	Arthrogryposis	SLC18A3 DYNC1H1	3.55e-03	21	125	2	C0003886
Disease	obesity (biomarker_via_orthology)	PDE3A PTPRF PIK3R1 EHD1	3.60e-03	147	125	4	DOID:9970 (biomarker_via_orthology)
Disease	pentachlorophenol measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022071
Disease	parathion measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022070
Disease	potassium chromate measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022072
Disease	mercuric chloride measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022068
Disease	heptachlor epoxide measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022067
Disease	methoxychlor measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022069
Disease	4,6-dinitro-o-cresol measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022053
Disease	2,4,5-trichlorophenol measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022052
Disease	azinphos methyl measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022055
Disease	aldrin measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022054
Disease	dicofol measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022060
Disease	disulfoton measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022062
Disease	dieldrin measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022061
Disease	endrin measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022064
Disease	endosulfan measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022063
Disease	heptachlor measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022066
Disease	ethion measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022065
Disease	chlorpyrifos measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022057
Disease	cadmium chloride measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022056
Disease	diazinon measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022059
Disease	dibutyl phthalate measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0022058
Disease	environmental exposure measurement	SLC2A9 MUC16 USH2A	3.72e-03	73	125	3	EFO_0008360
Disease	DDT metabolite measurement	SLC2A9 MUC16 USH2A	3.86e-03	74	125	3	EFO_0007886
Disease	triacylglycerol 48:2 measurement	SLC22A15 CSMD1	3.89e-03	22	125	2	EFO_0010405
Disease	triacylglycerol 48:3 measurement	SLC22A15 CSMD1	3.89e-03	22	125	2	EFO_0010406
Disease	triacylglycerol 58:9 measurement	PTGES2 CSMD1	3.89e-03	22	125	2	EFO_0010443
Disease	nephrosis (biomarker_via_orthology)	EDN1 LRP2	3.89e-03	22	125	2	DOID:2527 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
EPTLEASWPHLQLVY	PPP2R5E	141	Q16537
LAPVHITWAPVINSY	ESX1	386	Q8N693
REITGYLNIQSWPPH	ERBB3	391	P21860
SPLHALLREWTTYPE	DAPK1	1356	P53355
SYSPTGLPLIQLWSV	AKAP1	861	Q92667
IHPSTGLIYTQPWAS	CDHR1	521	Q96JP9
NHGIGTLSSPLYIAW	BUB1	91	O43683
GAWTILPLLPHFSVT	B3GLCT	106	Q6Y288
TWRISLPIGYGAHIQ	CSMD1	2001	Q96PZ7
PALTLHPWIYGQQYT	ABCA4	1401	P78363
WLPRLHISSYLPNDT	TBC1D32	1101	Q96NH3
GLPNTLPTAWHNLVY	SMPD1	546	P17405
TQVLPVGWSPYHQAS	BCORL1	826	Q5H9F3
MHPQWIGLITSTLPY	DOP1A	1656	Q5JWR5
VLYSLPKAHTVPTWP	ERVV-2	196	B6SEH9
LLPPSYSKTQLTEWH	CCDC180	406	Q9P1Z9
PLTWQTSHPYILADR	BMS1	246	Q14692
THILPPTIVRSYEWN	CFAP206	521	Q8IYR0
SQHYKPEWPALSGLV	ANKRD33	256	Q7Z3H0
PPTNQWYHGKLDRTI	RASA1	176	P20936
IHPYISWRLQSPGDK	IQCJ	106	Q1A5X6
EILHFYKWTSPPGVI	OCLN	51	Q16625
QYTGHITWTPPAIFK	CHRNA1	131	P02708
HIPITLYPSILTFPW	NUP210	451	Q8TEM1
LYVNGFTHWIPVPTS	MUC16	12656	Q8WXI7
PTHILYAVNASWVGL	NOL9	566	Q5SY16
HLWYLLPPTASISRA	NUP98	1431	P52948
VQVVGSNWPKPHYTL	LONP2	86	Q86WA8
SNWPKPHYTLLITGL	LONP2	91	Q86WA8
PPSEVTYQQTLLHVW	GREB1	701	Q4ZG55
HTLISPYNEIHWPAS	GREB1	826	Q4ZG55
INGGHPPWTILDYIQ	NAA60	181	Q9H7X0
PPWTILDYIQHLGSA	NAA60	186	Q9H7X0
IHPIPGNYTFTWTAR	KCNN2	226	Q9H2S1
YWVTPAGLRLTPAHA	LRRN2	456	O75325
THPYHILLSWVTPPN	LRRN2	536	O75325
YPSGSVALPSQWLLI	ERN2	346	Q76MJ5
PQTWSATHSYLDPPL	LARP4B	361	Q92615
DLLASSRHWPPVYVV	HMGXB3	1086	Q12766
APDTGYLWHVPLTFI	ERAP1	556	Q9NZ08
PRPVYTNHWAVQVLG	PCSK6	66	P29122
LHAVWYLTTQPIPGL	PDE3A	761	Q14432
LHAVWYLTTRPVPGL	PDE3B	746	Q13370
SPGQALYNIISTWPH	PGLYRP4	356	Q96LB8
SIIYSTIWSPHIPGC	PEX7	156	O00628
QAQPGPWEYHSAVLT	ERAL1	326	O75616
FHTTRWVPPLIGELY	NDUFA13	111	Q9P0J0
TQGYQHIWSLPVAPF	MYRFL	856	Q96LU7
EAIPWPGTLAIVHSY	PHF21A	541	Q96BD5
TPKSLHPWYGITPTS	MICALL1	456	Q8N3F8
HPSLVAVQSGLWPAL	GCN1	676	Q92616
YNIQWPLGIVAVHPS	LRP2	1681	P98164
LGPLATYISPHLWAQ	MSLNL	241	Q96KJ4
PYCPLWVSATHLLQG	FANCG	446	O15287
LIRSPSIPHQYWLTL	PIK3R1	226	P27986
VHIMTQPPSGEWLYL	PITPNM2	1041	Q9BZ72
SHVLWPYLLQFLTPV	MROH1	481	Q8NDA8
GQHWETTVPLLLGYL	MROH1	576	Q8NDA8
SHIQYFQWGRPVPST	POM121L12	61	Q8N7R1
QAPLSWELVRPHIYG	METTL7A	226	Q9H8H3
SWLHQSQAGPLPLSY	MOGS	546	Q13724
TIHWLPPISGVVYDR	PAPPA2	861	Q9BXP8
FPLNYSSIVGHTLWV	CUBN	1816	O60494
WRYVSSLPQPLAAHA	KLHL14	451	Q9P2G3
TIKPSILGFDTPHYW	KDM3A	931	Q9Y4C1
QLLPTSAWGTHYVVP	FCGBP	241	Q9Y6R7
LINIIGIHYNPTVWP	CYP4F11	421	Q9HBI6
PYVLNVTAVHPWGSS	EBI3	101	Q14213
SHVYIAWNLPLENPG	GALNT17	411	Q6IS24
IHWNGPAPRTTFLYL	CEMIP2	1046	Q9UHN6
ESAIWGPLHYSRPVL	MDH1B	331	Q5I0G3
STLHYVWSSLGPLAV	GLMP	66	Q8WWB7
VLTFILSALWHGVYP	MBOAT1	371	Q6ZNC8
TTDVKWHLSSLAPPY	CEP192	2301	Q8TEP8
VKGILPRSWSHYTVP	DYNC1H1	4456	Q14204
TLTLQDHAPWVPYLS	SLC2A9	401	Q9NRM0
DHAPWVPYLSIVGIL	SLC2A9	406	Q9NRM0
GPWNLPQSSYSHLTR	ECM1	191	Q16610
VGPWYHLSAQEIQPL	ENGASE	421	Q8NFI3
PISTLWYLGHLLLPS	FCRLB	56	Q6BAA4
TQFGLWTPHYLILLG	GPR146	241	Q96CH1
IIWVNTPEHVVPYGL	EDN1	71	P05305
RVYIGSFWSHPLLIP	EHD1	251	Q9H4M9
AILIALVGATPSYHW	SLC22A15	36	Q8IZD6
PSLLAALEPHVYEWT	D2HGDH	451	Q8N465
GKVPHLWGQSLYILS	PHKA2	396	P46019
TLWNHSLQPYPLLES	NRROS	71	Q86YC3
PGYLPTSLAWHPQQS	WDR77	211	Q9BQA1
YVITTPAGLIIKWSH	OTOGL	1646	Q3ZCN5
NSTAVHVYWKLPVPS	PTPRF	721	P10586
LPPQHGLELLTVYAW	OAS3	966	Q9Y6K5
TYECLIWPLLSTVHP	NUP88	486	Q99567
GTPLDPQWILEIHYS	MOXD2P	296	A6NHM9
RGVQHLYGQPWPTVT	MMP11	251	P24347
HPILNDPIYNSVAWG	RPUSD2	381	Q8IZ73
TAIYPWGHSFILILG	TAS2R10	266	Q9NYW0
SSWVLLYTAQLPPEH	USH2A	2131	O75445
WFSPVHTYPLLATRL	SNTB1	366	Q13884
WLPAFVPHVLGVYLT	SLC18A3	331	Q16572
HWSVIFSDTPYLPLL	TBC1D31	486	Q96DN5
HGPSILYPSTVWDFI	SH3BP4	456	Q9P0V3
TVWLIHGYRPVGSIP	LIPI	76	Q6XZB0
HGYRPVGSIPLWLQN	LIPI	81	Q6XZB0
HGTELIPWYVLSIQA	PLCE1	841	Q9P212
AKNYPPWQHTTLSVL	LARS1	941	Q9P2J5
PGNPDLYHVLSVIWQ	TFB2M	241	Q9H5Q4
WLVHLISPNVYRTPT	PTGES2	241	Q9H7Z7
YLHSAPWNPLSSSLQ	STARD9	1726	Q9P2P6
YLWPQGLVRESHPSL	SLC38A8	196	A6NNN8
SHGVPLPNWLINSYK	NUP160	1316	Q12769
RVYIGSFWSHPLLIP	EHD3	251	Q9NZN3
YPSRVNHLILVEPWG	ABHD5	166	Q8WTS1
WVLPILTQFTPYLGH	PRAMEF6	216	Q5VXH4
IWLSPLYPRIADGTH	TDP1	296	Q9NUW8
GIWLSGITHIYSPQV	STIL	261	Q15468
LFGIPLWYHSQSPRV	SUN2	576	Q9UH99
LWYHSQSPRVILQPD	SUN2	581	Q9UH99
VTGLPYPTISWFHNG	SPEG	1211	Q15772
LTWTPPSAQIHGYIL	TNN	991	Q9UQP3
IWGSSQLIDHPYLEP	PTPA	256	Q15257
PLPSNILEWHYVVRG	UBE2J2	36	Q8N2K1
TAYGVPLPLSIQWHW	FLT4	446	P35916
WVLPILTQFTPYLGH	PRAMEF5	216	Q5TYX0
VQLYLALPPGAEHWT	WAS	51	P42768
VLWCLLPQTGYVHPD	PIGZ	46	Q86VD9
YVITTQHWLGLLGPN	DCT	156	P40126
KWSPLILNPSYTILH	PLCH1	861	Q4KWH8
QTAHIWRYAVQLPTP	WDR37	221	Q9Y2I8
ISDPTILWRAYPHNL	TRAM1	146	Q15629
LPYLQNWSHPKSVIV	UEVLD	111	Q8IX04
SVGSVWFVLPHIYPI	TRAPPC10	761	P48553
HPPNYIVLWNADTGT	WDR11	136	Q9BZH6
PNIWSLLAAPGSITH	VWA7	31	Q9Y334
HYVLPPQLQLTSWDG	WDR87	746	Q6ZQQ6
LPFWLYVIITSSLPH	TMEM267	176	Q0VDI3
EISTLAVYRLPHPGW	TPCN2	516	Q8NHX9
GGSVRPSYWLVLHNL	TNRC6B	1641	Q9UPQ9
PSYWLVLHNLTPQID	TNRC6B	1646	Q9UPQ9
ALYPINISAAWHLGP	VN1R2	11	Q8NFZ6
YRPHVDPWVISISSL	VPS13D	71	Q5THJ4
GYVHPVNLTWPFVVS	MSC	171	O60682
YLPWAHTKPVVTLTS	MYOF	631	Q9NZM1