Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesspositive regulation of Wnt protein secretion

TMEM132A PTPN23

3.17e-054482GO:0061357
GeneOntologyBiologicalProcessregulation of Wnt protein secretion

TMEM132A PTPN23

5.28e-055482GO:0061356
GeneOntologyBiologicalProcessWnt protein secretion

TMEM132A PTPN23

7.91e-056482GO:0061355
DomainDUF3454

NOTCH1 NOTCH3

1.86e-053472PF11936
DomainDUF3454_notch

NOTCH1 NOTCH3

1.86e-053472IPR024600
DomainDUF3454

NOTCH1 NOTCH3

1.86e-053472SM01334
DomainNotch

NOTCH1 NOTCH3

3.71e-054472IPR008297
DomainNODP

NOTCH1 NOTCH3

3.71e-054472PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH3

3.71e-054472IPR011656
DomainNotch_NOD_dom

NOTCH1 NOTCH3

3.71e-054472IPR010660
DomainNOD

NOTCH1 NOTCH3

3.71e-054472PF06816
DomainNOD

NOTCH1 NOTCH3

3.71e-054472SM01338
DomainNODP

NOTCH1 NOTCH3

3.71e-054472SM01339
DomainEGF_1

UMODL1 ADAM33 USH2A SSPOP NOTCH1 NOTCH3

4.10e-05255476PS00022
Domainfn3

PTPRD UMODL1 OBSCN ROBO2 USH2A

5.27e-05162475PF00041
DomainLNR

NOTCH1 NOTCH3

6.17e-055472PS50258
DomainFN3

PTPRD UMODL1 OBSCN ROBO2 USH2A

9.89e-05185475SM00060
DomainNotch_dom

NOTCH1 NOTCH3

1.29e-047472IPR000800
DomainNotch

NOTCH1 NOTCH3

1.29e-047472PF00066
DomainNL

NOTCH1 NOTCH3

1.29e-047472SM00004
DomainFN3

PTPRD UMODL1 OBSCN ROBO2 USH2A

1.39e-04199475PS50853
DomainFN3_dom

PTPRD UMODL1 OBSCN ROBO2 USH2A

1.75e-04209475IPR003961
DomainEGF_3

UMODL1 ADAM33 SSPOP NOTCH1 NOTCH3

3.01e-04235475PS50026
DomainEGF_extracell

ADAM33 NOTCH1 NOTCH3

4.62e-0460473IPR013111
DomainEGF_2

ADAM33 NOTCH1 NOTCH3

4.62e-0460473PF07974
DomainEGF_2

UMODL1 ADAM33 SSPOP NOTCH1 NOTCH3

5.22e-04265475PS01186
DomainEMI

UMODL1 SSPOP

8.23e-0417472PS51041
DomainEGF_CA

UMODL1 NOTCH1 NOTCH3

1.32e-0386473PF07645
DomainPentatricopeptide_repeat

DENND4B GNAS

1.52e-0323472IPR002885
DomainEGF_Ca-bd_CS

UMODL1 NOTCH1 NOTCH3

1.87e-0397473IPR018097
DomainEGF_CA

UMODL1 NOTCH1 NOTCH3

1.98e-0399473PS01187
DomainASX_HYDROXYL

UMODL1 NOTCH1 NOTCH3

2.04e-03100473PS00010
DomainhEGF

NOTCH1 NOTCH3

2.25e-0328472PF12661
DomainEGF-type_Asp/Asn_hydroxyl_site

UMODL1 NOTCH1 NOTCH3

2.40e-03106473IPR000152
DomainEGF

UMODL1 ADAM33 NOTCH1 NOTCH3

2.85e-03235474SM00181
DomainEGF-like_dom

UMODL1 ADAM33 NOTCH1 NOTCH3

3.51e-03249474IPR000742
DomainEGF_CA

UMODL1 NOTCH1 NOTCH3

3.58e-03122473SM00179
DomainPTPc

PTPRD PTPN23

3.70e-0336472SM00194
DomainEGF-like_Ca-bd_dom

UMODL1 NOTCH1 NOTCH3

3.74e-03124473IPR001881
DomainEGF-like_CS

UMODL1 ADAM33 NOTCH1 NOTCH3

4.15e-03261474IPR013032
DomainTYR_PHOSPHATASE_PTP

PTPRD PTPN23

4.33e-0339472PS50055
DomainPTPase_domain

PTPRD PTPN23

4.77e-0341472IPR000242
DomainY_phosphatase

PTPRD PTPN23

4.77e-0341472PF00102
DomainGrowth_fac_rcpt_

UMODL1 NOTCH1 NOTCH3

7.08e-03156473IPR009030
DomainIg-like_fold

PTPRD UMODL1 OBSCN KIR3DL3 ROBO2 USH2A

8.20e-03706476IPR013783
DomainPTPc_motif

PTPRD PTPN23

9.68e-0359472SM00404
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH1 NOTCH3

5.96e-055352M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH3

5.96e-055352MM14733
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH1 NOTCH3

8.93e-056352M27068
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH3

1.25e-047352MM14734
PathwayWP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES

EPN3 REPS1 DNM3 ARHGAP27 FCHO1 SLC27A4

3.13e-04381356M48063
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH1 NOTCH3

3.25e-0411352M47865
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH1 NOTCH3

3.89e-0412352M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH1 NOTCH3

3.89e-0412352M47533
PathwayPID_NOTCH_PATHWAY

SSPOP NOTCH1 NOTCH3

4.14e-0459353M17
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH3

4.59e-0413352M47423
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH1 NOTCH3

4.59e-0413352M47534
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

SSPOP NOTCH1 NOTCH3

6.29e-0468353M27303
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH3

8.94e-0418352M614
Pubmed

Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity.

NOTCH1 NOTCH3 SLC27A4

2.19e-07949318507503
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

KIAA1671 ABLIM1 TBKBP1 OBSCN MYRIP PARD3B CACNA1H GNAS SSPOP TET3 JMJD1C NOTCH3

7.68e-071489491228611215
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

KIAA1671 ABLIM1 TMEM131 JMJD1C RNF43 PRRC2B

1.88e-0626349634702444
Pubmed

Notch1 and Notch3 coordinate for pericyte-induced stabilization of vasculature.

NOTCH1 NOTCH3

1.94e-06249234878922
Pubmed

Individual common variants exert weak effects on the risk for autism spectrum disorders.

TAF1C PARD3B

1.94e-06249222843504
Pubmed

The Expression of Notch 1 and Notch 3 in Gallbladder Cancer and Their Clinicopathological Significance.

NOTCH1 NOTCH3

1.94e-06249226634853
Pubmed

A protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 interacts with Notch1 and Notch3.

NOTCH1 NOTCH3

1.94e-06249221191019
Pubmed

Notch3 and IL-1beta exert opposing effects on a vascular smooth muscle cell inflammatory pathway in which NF-kappaB drives crosstalk.

NOTCH1 NOTCH3

1.94e-06249217881497
Pubmed

The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia.

NOTCH1 NOTCH3

1.94e-06249229023469
Pubmed

Nuclear Notch3 expression is associated with tumor recurrence in patients with stage II and III colorectal cancer.

NOTCH1 NOTCH3

1.94e-06249224728738
Pubmed

Distinct roles for Notch1 and Notch3 in human adipose-derived stem/stromal cell adipogenesis.

NOTCH1 NOTCH3

1.94e-06249233021719
Pubmed

Combined deficiency of Notch1 and Notch3 causes pericyte dysfunction, models CADASIL, and results in arteriovenous malformations.

NOTCH1 NOTCH3

1.94e-06249226563570
Pubmed

Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation.

NOTCH1 NOTCH3

1.94e-06249214595837
Pubmed

Nonoverlapping functions for Notch1 and Notch3 during murine steady-state thymic lymphopoiesis.

NOTCH1 NOTCH3

1.94e-06249221768299
Pubmed

Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway.

NOTCH1 NOTCH3

1.94e-06249225700162
Pubmed

Evidence of Notch pathway activation in the ectatic ducts of chronic pancreatitis.

NOTCH1 NOTCH3

1.94e-06249218069660
Pubmed

Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors.

NOTCH1 NOTCH3

1.94e-06249216507912
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPN3 TBKBP1 REPS1 MROH6 TMEM132A OBSCN CACNA1H RNF43 NOTCH1 PRRC2B

2.68e-061105491035748872
Pubmed

Notch-mediated CBF-1/RBP-J{kappa}-dependent regulation of human vascular smooth muscle cell phenotype in vitro.

NOTCH1 NOTCH3

5.83e-06349215987768
Pubmed

Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.

NOTCH1 NOTCH3

5.83e-0634927615640
Pubmed

Notch receptor expression in human brain arteriovenous malformations.

NOTCH1 NOTCH3

5.83e-06349225846406
Pubmed

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium.

NOTCH1 NOTCH3

5.83e-0634927918097
Pubmed

Complementary and combinatorial patterns of Notch gene family expression during early mouse development.

NOTCH1 NOTCH3

5.83e-0634928645602
Pubmed

Notch/CXCR4 Partnership in Acute Lymphoblastic Leukemia Progression.

NOTCH1 NOTCH3

5.83e-06349231346528
Pubmed

PD-L1 and Notch as novel biomarkers in pancreatic sarcomatoid carcinoma: a pilot study.

NOTCH1 NOTCH3

5.83e-06349234846251
Pubmed

Expression of Notch1 to -4 and their ligands in renal cell carcinoma: a tissue microarray study.

NOTCH1 NOTCH3

5.83e-06349221471519
Pubmed

Smooth muscle Notch1 mediates neointimal formation after vascular injury.

NOTCH1 NOTCH3

5.83e-06349219433762
Pubmed

Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis.

NOTCH1 NOTCH3

5.83e-06349227697639
Pubmed

NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network.

NOTCH1 NOTCH3

5.83e-06349220801121
Pubmed

Notch signaling regulates platelet-derived growth factor receptor-beta expression in vascular smooth muscle cells.

NOTCH1 NOTCH3

5.83e-06349218483410
Pubmed

KCTD10 regulates brown adipose tissue thermogenesis and metabolic function via Notch signaling.

NOTCH1 NOTCH3

5.83e-06349234854382
Pubmed

Overlapping but distinct roles for NOTCH receptors in human cardiovascular disease.

NOTCH1 NOTCH3

5.83e-06349229767458
Pubmed

The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation.

NOTCH1 NOTCH3

5.83e-0634927698746
Pubmed

Hepatitis B virus X protein and hypoxia‑inducible factor-1α stimulate Notch gene expression in liver cancer cells.

NOTCH1 NOTCH3

5.83e-06349227840976
Pubmed

Class II phosphatidylinositol 3-kinase-C2α is essential for Notch signaling by regulating the endocytosis of γ-secretase in endothelial cells.

NOTCH1 NOTCH3

5.83e-06349233664344
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH1 NOTCH3

1.16e-05449228061457
Pubmed

Hepatitis C virus NS3 protein can activate the Notch-signaling pathway through binding to a transcription factor, SRCAP.

NOTCH1 NOTCH3

1.16e-05449221673954
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH1 NOTCH3

1.16e-05449224145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH1 NOTCH3

1.16e-05449220069356
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH1 NOTCH3

1.16e-05449219404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH1 NOTCH3

1.16e-05449228669409
Pubmed

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.

NOTCH1 NOTCH3

1.16e-05449210551863
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH1 NOTCH3

1.16e-05449211466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH1 NOTCH3

1.16e-05449224151014
Pubmed

Activation of Notch signaling in human tongue carcinoma.

NOTCH1 NOTCH3

1.16e-05449220819128
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH1 NOTCH3

1.16e-05449211401408
Pubmed

Novel MIR143-NOTCH fusions in benign and malignant glomus tumors.

NOTCH1 NOTCH3

1.16e-05449223999936
Pubmed

Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma.

NOTCH1 NOTCH3

1.16e-05449229170450
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH1 NOTCH3

1.16e-05449210194420
Pubmed

NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells.

NOTCH1 NOTCH3

1.16e-05449218156632
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH1 NOTCH3

1.16e-0544928898100
Pubmed

Notch signalling is linked to epidermal cell differentiation level in basal cell carcinoma, psoriasis and wound healing.

NOTCH1 NOTCH3

1.16e-05449211978185
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH1 NOTCH3

1.16e-05449211459941
Pubmed

p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro.

NOTCH1 NOTCH3

1.16e-05449212391150
Pubmed

Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.

NOTCH1 NOTCH3

1.16e-05449220829372
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH1 NOTCH3

1.16e-05449218184405
Pubmed

CDKN1C/P57 is regulated by the Notch target gene Hes1 and induces senescence in human hepatocellular carcinoma.

NOTCH1 NOTCH3

1.16e-05449222705236
Pubmed

Detection of Notch signaling molecules in cemento-ossifying fibroma of the jaws.

NOTCH1 NOTCH3

1.16e-05449220040020
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH1 NOTCH3

1.16e-05449215917835
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH1 NOTCH3

1.16e-05449223444212
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH1 NOTCH3

1.16e-05449217920003
Pubmed

Analysis of HeyL expression in wild-type and Notch pathway mutant mouse embryos.

NOTCH1 NOTCH3

1.16e-05449211044625
Pubmed

Notch signaling in bulge stem cells is not required for selection of hair follicle fate.

NOTCH1 NOTCH3

1.94e-05549219211676
Pubmed

A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons.

NOTCH1 NOTCH3

1.94e-05549227040987
Pubmed

Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors.

NOTCH1 NOTCH3

1.94e-05549211006133
Pubmed

Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.

NOTCH1 NOTCH3

1.94e-05549221124806
Pubmed

Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells.

NOTCH1 NOTCH3

1.94e-05549215879553
Pubmed

Functional diversity of notch family genes in fetal lung development.

NOTCH1 NOTCH3

1.94e-05549215064243
Pubmed

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.

NOTCH1 NOTCH3

1.94e-05549221562564
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

NOTCH1 NOTCH3

1.94e-05549223675950
Pubmed

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

NOTCH1 NOTCH3

1.94e-05549211101851
Pubmed

Notch expression in developing olfactory neuroepithelium.

NOTCH1 NOTCH3

1.94e-05549215076712
Pubmed

Notch3 drives development and progression of cholangiocarcinoma.

NOTCH1 NOTCH3

1.94e-05549227791012
Pubmed

Chimeric analysis of Notch2 function: a role for Notch2 in the development of the roof plate of the mouse brain.

NOTCH1 NOTCH3

1.94e-05549212242712
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH1 NOTCH3

1.94e-05549215882997
Pubmed

Deficiency of Notch signaling in pericytes results in arteriovenous malformations.

NOTCH1 NOTCH3

1.94e-05549233148887
Pubmed

Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.

NOTCH1 NOTCH3

1.94e-05549220554499
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

ROBO2 ADAM33 ECM1 SSPOP NOTCH1 HCLS1 PRRC2B

2.19e-0560849716713569
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ABLIM1 DENND4B DNM3 CACNA1H TET3 PRRC2B

2.26e-0540749612693553
Pubmed

RBP-L, a transcription factor related to RBP-Jkappa.

NOTCH1 NOTCH3

2.91e-0564929111338
Pubmed

Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.

NOTCH1 NOTCH3

2.91e-05649220870902
Pubmed

The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis.

NOTCH1 NOTCH3

2.91e-05649226062937
Pubmed

A study on Notch signaling in human breast cancer.

NOTCH1 NOTCH3

2.91e-05649217822320
Pubmed

The origin of the ankyrin repeat region in Notch intracellular domains is critical for regulation of HES promoter activity.

NOTCH1 NOTCH3

2.91e-05649211404076
Pubmed

ALDH maintains the stemness of lung adenoma stem cells by suppressing the Notch/CDK2/CCNE pathway.

NOTCH1 NOTCH3

2.91e-05649224671051
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

NOTCH1 NOTCH3

2.91e-05649212244553
Pubmed

Profiling immunohistochemical expression of NOTCH1-3, JAGGED1, cMET, and phospho-MAPK in 100 carcinomas of unknown primary.

NOTCH1 NOTCH3

2.91e-05649222526456
Pubmed

Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes.

NOTCH1 NOTCH3

2.91e-05649231249304
Pubmed

Loss of notch activity in the developing central nervous system leads to increased cell death.

NOTCH1 NOTCH3

2.91e-05649216508303
Pubmed

Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.

NOTCH1 NOTCH3

2.91e-05649219503073
Pubmed

Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment.

NOTCH1 NOTCH3

2.91e-05649219573812
Pubmed

Expression of Deltex1 during mouse embryogenesis: comparison with Notch1, 2 and 3 expression.

NOTCH1 NOTCH3

2.91e-05649211731257
Pubmed

Aberrant expression of Notch signaling molecules in patients with immune thrombocytopenic purpura.

NOTCH1 NOTCH3

2.91e-05649219603167
Pubmed

Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3.

NOTCH1 NOTCH3

2.91e-0564927835890
Pubmed

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.

NOTCH1 NOTCH3

2.91e-05649218299578
Pubmed

Trisomy 12 chronic lymphocytic leukemia cells exhibit upregulation of integrin signaling that is modulated by NOTCH1 mutations.

ITGAL NOTCH1

2.91e-05649224829201
Pubmed

Mouse Serrate-1 (Jagged-1): expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4.

NOTCH1 NOTCH3

2.91e-0564929108364
Pubmed

Delta-notch signaling in odontogenesis: correlation with cytodifferentiation and evidence for feedback regulation.

NOTCH1 NOTCH3

2.91e-0564929882480
Pubmed

Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.

NOTCH1 NOTCH3

2.91e-05649215019995
Pubmed

Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

NOTCH1 NOTCH3

2.91e-05649222615412
GeneFamilyFibronectin type III domain containing

PTPRD OBSCN ROBO2 USH2A

2.50e-04160354555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

PTPRD OBSCN ROBO2

3.68e-03161353593
ToppCell(01)_Cycling_Basal_(homeostasis)-(1)_24hpi|(01)_Cycling_Basal_(homeostasis) / shred by cell type and Timepoint

TRIM16 TBKBP1 ROBO2 USH2A

1.14e-06714946aa56b0daaeb5e0ae30619f9c6945c8e42899b27
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

TRIM16 MAP1A MROH6 ECM1 FCHO1

1.88e-06186495701eea0016d69f0f9d29b613948f91239096e6c7
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

TBKBP1 DNM3 DRC1 ECM1

1.57e-05137494b553958e7e6dcd887d860e34d3983cbb85cefaa6
ToppCellfacs-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 DENND4B ITGAL HCLS1

2.88e-05160494bc4a93dc5f37829799c37877e751ff3bc122e4ab
ToppCellHealthy_Control-Myeloid-Mast|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PROX2 OBSCN MYRIP DNM3

4.09e-05175494ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCellHealthy_Control-Myeloid-Mast-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PROX2 OBSCN MYRIP DNM3

4.09e-05175494eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_26.46.91|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1A ADAM33 ECM1 NOTCH3

4.18e-0517649429b71369503719c74888cd356ceb6724cfdcabd9
ToppCelldroplet-Skin-nan-18m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ITGAL SSPOP HCLS1

4.37e-0517849412d5c6be6cfbf733e3cb02780606b3725eda7d2b
ToppCelldroplet-Skin-nan-18m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ITGAL SSPOP HCLS1

4.37e-05178494e0769ad06f92423a3cb6c78a61da3ba5bd9b4eae
ToppCelldroplet-Skin-nan-18m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ITGAL SSPOP HCLS1

4.37e-0517849411c2ce093b7538518c8d4497dc5b0b4da22bf1a8
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ROBO2 PARD3B ECM1 NOTCH3

4.46e-0517949498c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTPRD OBSCN CACNA1H NOTCH3

4.46e-05179494dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

UMODL1 ARHGAP27 FCHO1 HCLS1

4.66e-0518149451e4d6bfdbf414d8e30aee2e6f7492f4f7f54373
ToppCellnormal_Lung-Fibroblasts-Pericytes|normal_Lung / Location, Cell class and cell subclass

OBSCN CACNA1H ECM1 NOTCH3

4.66e-05181494f74941e49950027360d71ea3b205fc20c6929766
ToppCellwk_08-11-Hematologic-Myeloid-pre-pDC/DC5|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

UMODL1 ITGAL FCHO1 HCLS1

4.76e-05182494fec8a2d6d4099722b8e1bb41222108ed74268fcf
ToppCellPericytes-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MAP1A ADAM33 CACNA1H NOTCH3

4.86e-051834944617b18da8d699a44e4c47980197b1e7eb951470
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRD OBSCN USH2A SSPOP

4.97e-051844942cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRD OBSCN USH2A SSPOP

4.97e-05184494ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRD OBSCN USH2A SSPOP

4.97e-051844942b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRD OBSCN CACNA1H NOTCH3

5.29e-0518749486250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO2 ADAM33 CACNA1H NOTCH3

5.51e-05189494127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO2 ADAM33 CACNA1H NOTCH3

5.51e-051894942cfb4d12f75678d1619f4743838a0e954bd57761
ToppCell(4)_Endothelial_cells-(40)_EC-arterial|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

TRIM16 ABLIM1 MYRIP DNM3

5.63e-05190494ff774faf3f12759d11e50ed7d189288bb79e22e1
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

OBSCN CACNA1H ECM1 NOTCH3

5.74e-051914941626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

OBSCN CACNA1H ECM1 NOTCH3

5.74e-05191494716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCellP28-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MAP1A ADAM33 ECM1 NOTCH3

5.86e-0519249487c7780cf72f4c204f2a5f6655309d47a23c08ae
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTPRD ROBO2 ADAM33 ECM1

5.86e-05192494b9e4585bea280ca0ae159f0c6a2bf7b88a15a6e6
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

DRC1 PARD3B NOTCH1 NOTCH3

6.47e-0519749461749ccafeb938c310cff1de5ff924a1c794325a
ToppCelldistal-mesenchymal-Vascular_Smooth_Muscle-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAM33 CACNA1H ECM1 NOTCH3

6.47e-05197494da653dc7d216e202f390e5ab0245f243e3ed213b
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

DRC1 PARD3B NOTCH1 NOTCH3

6.47e-051974949d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCelldistal-2-mesenchymal-Vascular_Smooth_Muscle|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAM33 CACNA1H ECM1 NOTCH3

6.60e-05198494ce05ede69c167b2294630709bb0c223483a6ef75
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

ABLIM1 PTPRD DNM3 ROBO2

6.73e-051994941b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

ABLIM1 PTPRD DNM3 ROBO2

6.73e-051994944bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellTransverse-T_cell-Tfh|T_cell / Region, Cell class and subclass

OBSCN ARHGAP27 TET3 NOTCH1

6.73e-0519949433ffea12b8228e0b5bd8942531c3b21d24224725
ToppCelldistal-mesenchymal-Pericyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

OBSCN CACNA1H ECM1 NOTCH3

6.86e-05200494867935701fac71a3fe01578362da0676f959736c
ToppCellCOVID-19_Mild-Neu_3|World / 5 Neutrophil clusters in COVID-19 patients

MAP1A OBSCN ROBO2

3.27e-041224932aa9cfadab70312882ae679e3788fc7ab996c0f3
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MAP1A DNM3 ECM1

3.35e-04123493064e272ee307af0b3f85bb8bafe7f0195ddc3d52
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAP1A DNM3 ECM1

3.35e-04123493977d91f95c63996cbc1eb9280e12bb55c8b452c8
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Slco2a1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TRIM16 CACNA1H NDUFA3

4.21e-041334939d7a08170d38ae9b2ff10a0fa505aeb3aae2824d
ToppCellLPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TAF1C MYRIP ITGAL

4.21e-041334932ec3490cbf60152c3cece95eb566d749c9666517
ToppCellPND01-03-samps-Myeloid-Granulocyte|PND01-03-samps / Age Group, Lineage, Cell class and subclass

RASGRP4 ITGAL HCLS1

5.87e-041494937bdb396de8a1ef27ab0c2aaf1452576f4b0b5561
ToppCellPND01-03-samps-Myeloid-Granulocyte-neutrophil__Lgals3-negative|PND01-03-samps / Age Group, Lineage, Cell class and subclass

RASGRP4 ITGAL HCLS1

5.87e-0414949350f53018e525b3d252caa8bed9e075b1bb1086dd
ToppCelldroplet-Limb_Muscle-nan-18m-Myeloid-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGAL HCLS1 SLC27A4

5.98e-04150493a003cbaf25a1b5ad4d361dcf162afe0c4b8b78f8
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TMEM132A OBSCN B4GALNT3

5.98e-041504939d5bbdca19da60e1a2121ef64ec8e1375a5dbf6d
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

TMEM132A OBSCN B4GALNT3

6.33e-04153493b37a1ecad389d2848b8ca4d287823e8048207420
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-capillary_endothelial_Hpgd-CA4_high|E18.5-samps / Age Group, Lineage, Cell class and subclass

TRIM16 DRC1 ECM1

6.46e-04154493212c340a096a3a9669d1aebd61c045cf1402a868
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ITGAL HCLS1

6.70e-04156493c841faa1695ff577b0774f531adf1343d05dce9e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ITGAL HCLS1

6.70e-0415649321baf8c6e62bb7fd1530c2c100f73c0cecee092e
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ITGAL FCHO1

6.95e-04158493b0508a600994090c6aafd8d779437190a33ad821
ToppCellAdult-Mesenchymal-myofibroblast_cell-D122|Adult / Lineage, Cell type, age group and donor

TMEM132A ROBO2 ECM1

6.95e-04158493410fa08c9d880d27e80ec939fa5ba5a41dcb31ab
ToppCellfacs-Lung-EPCAM-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ITGAL FCHO1

6.95e-04158493a816cc095452308d06f87b77467e2a8c6361fd2a
ToppCellfacs-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DENND4B ITGAL HCLS1

6.95e-04158493121d63b8e2e37107467b170e5b2c798a7dbf6325
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD ROBO2 SSPOP

7.08e-04159493fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD ROBO2 SSPOP

7.08e-04159493aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRD ROBO2 SSPOP

7.08e-041594938bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABLIM1 MYRIP FCHO1

7.21e-0416049333050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Myeloid-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ITGAL HCLS1

7.48e-041624934c6e0cadd0ff50b0f50e0cfdc9027210e72674b9
ToppCellfacs-Lung-EPCAM-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ITGAL HCLS1

7.48e-04162493484ea4ac40de672dcbd2583a52cb7f385c918814
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ITGAL HCLS1

7.48e-04162493bba144ac5332bab9eba2ccf599703c781a7f88f1
ToppCelldroplet-Lung-nan-18m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNM3 DRC1 CACNA1H

7.61e-041634935efecdd8a069a822bc9d35b407092925a865e629
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

TAF1C DNM3 TET3

7.61e-041634939f5facfa1864eb63e2f8022ad7379d9252b7a254
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

OBSCN DRC1 ITGAL

7.61e-04163493218b9ba099cb27aa91c6b73bf89b44895f5dddc3
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tfh|GI_large-bowel / Manually curated celltypes from each tissue

UMODL1 DNM3 CACNA1H

7.61e-041634934104d3b9748b39cb0744c9be76db21bdda566a0d
ToppCelldroplet-Fat-Gat-18m-Myeloid-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ITGAL HCLS1

7.61e-041634933d12a8ca97005308403a3ab136af483ab25f9b0e
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNM3 DRC1 CACNA1H

7.61e-041634930d94a427f86e62aba12c397c6d7b8cd297f3a0e5
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ITGAL HCLS1

7.75e-0416449315d52666e5150e7c34b1f641a937fb2d5e8aaf8a
ToppCellfacs-Lung-EPCAM-24m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ITGAL HCLS1

7.75e-04164493d622f0d8d8bad48dfdf160ec63c545df192637a9
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM16 RASGRP4 SLC27A4

7.88e-04165493b671c6a950e70f64776c2104baccb3dc2bb6a1ba
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1A ADAM33 ECM1

7.88e-04165493f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAM33 CACNA1H NOTCH3

7.88e-041654938a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABLIM1 FCHO1 ATG16L2

8.02e-041664936a948aefd283a2572da37b59dbc142b6e686b024
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABLIM1 FCHO1 ATG16L2

8.02e-041664938d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCellfacs-Lung-3m-Hematologic-myeloid|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 ITGAL HCLS1

8.02e-041664937bf7c2854cf7d85b3ae07256bbe86ae9184d6b57
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RASGRP4 ITGAL ECM1

8.16e-041674931cd9e2af85c6c5b9e1d88991c87ac6980b387243
ToppCelldroplet-Lung-3m-Hematologic-myeloid|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 ITGAL HCLS1

8.16e-041674936f6f654d10cff83203415685f7707409626990ab
ToppCelldroplet-Kidney-nan-24m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ITGAL HCLS1

8.16e-041674932ee1660be117e20f24557522345572d11cbee813
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H ITGAL CCDC9

8.31e-0416849341da200bbff5c663c39f67c38d6d5f43b0ad9494
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNM3 CACNA1H FCHO1

8.31e-04168493ce9fae8b295c668b0959d5007a8bcd401d80e258
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H ITGAL CCDC9

8.31e-04168493a77259c13508f19186d7b0f80b34dc6d89497ab5
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1H ITGAL SSPOP

8.31e-04168493bc7d5f0e5d222922eaf1c8e8c87aab189209d6b6
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBKBP1 GJA10 NOTCH1

8.31e-0416849306dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PROX2 KIR3DL3 HCLS1

8.31e-04168493b4b73f3fc9f4c3d87ca0a63ff8b2842141ccd0e6
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBKBP1 GJA10 NOTCH1

8.31e-041684931002f058a340763e3d8de0bd1f0547a903526ec6
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPN3 ABLIM1 DRC1

8.45e-041694931de3ae36d3b60e961bfd9f7bdc37867b82a0417f
ToppCellnormal_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

OBSCN ECM1 NOTCH3

8.59e-04170493d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PROX2 ITGAL HCLS1

8.59e-0417049328fb192b21cdc5a77ba4f276694cff852eb2304b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPN3 RASGRP4 DRC1

8.59e-04170493be2a34c70665d8d11332b1a70eda03d77cb7f7dd
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABLIM1 SSPOP FCHO1

8.59e-04170493aff226a84e397ab58204325aa9d8b396a881986e
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASGRP4 ABLIM1 SMTNL1

8.59e-0417049355fe16d98ea284d05fb899888e4569c685644c7b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PROX2 ITGAL HCLS1

8.59e-04170493239cb4b801b2d71a6facb386f2684c0851504151
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABLIM1 SSPOP FCHO1

8.59e-041704936af16e6f276aec6389ece99505ba13c7edc4c4fa
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN ITGAL SLC27A4

8.74e-04171493355a27ea88410a84210f7e4298c7c4f90cf2f8a9
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABLIM1 TAF1C FCHO1

8.74e-041714932e7cc311005958af52f39ca6c310c85b43a85aaf
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

OBSCN CACNA1H NOTCH3

8.74e-04171493080003f698f867935c2bfc55d241d3650f45a0ab
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNM3 CACNA1H FCHO1

8.74e-04171493584a095ddcbf78aa29527f84b46b5ad3e2edbaa9
ToppCelldroplet-Liver-LIVER_NPC-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABLIM1 DNM3 CACNA1H

8.74e-0417149320ac3de9c164b409b70a30a8b6544ea491ef7c0e
ToppCellfacs-Lung-18m-Hematologic-myeloid|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 ITGAL HCLS1

8.74e-041714934ad28ecfde3d529a09b80be908c446bd5274518e
ToppCelldroplet-Liver-Npc-18m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGAL FCHO1 HCLS1

8.74e-04171493e9c42ce444d42cbb4f97e81393756531bfe61637
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABLIM1 TAF1C FCHO1

8.74e-041714934b599f953c8e5b947b2c8bbbf7fe6f9dc388e336
ToppCelldroplet-Limb_Muscle-nan-18m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGAL FCHO1 RNF43

8.74e-041714934198e7fef1aaee3d85722094f3e444655d393e9e
DiseaseLiver Diseases, Parasitic

ROBO2 GNAS RNF43

3.59e-079493C0023897
DiseaseIntrahepatic Cholangiocarcinoma

ROBO2 GNAS RNF43

8.50e-0624493C0345905
DiseaseExtrahepatic Cholangiocarcinoma

ROBO2 GNAS RNF43

8.50e-0624493C3805278
Diseasebrain cancer (implicated_via_orthology)

PROX2 NOTCH1 NOTCH3

1.09e-0526493DOID:1319 (implicated_via_orthology)
DiseaseCholangiocarcinoma

ROBO2 GNAS RNF43

1.09e-0526493C0206698
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH1 NOTCH3

5.64e-057492DOID:299 (implicated_via_orthology)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH1 NOTCH3

5.64e-057492DOID:3620 (implicated_via_orthology)
Diseasesusceptibility to shingles measurement

TBKBP1 MYRIP ROBO2

3.35e-0481493EFO_0008401
Diseasecholangiocarcinoma (is_implicated_in)

GNAS RNF43

6.11e-0422492DOID:4947 (is_implicated_in)
DiseaseCarcinoma, Pancreatic Ductal

NOTCH1 NOTCH3

7.28e-0424492C0887833
Diseaseimmature platelet count

DNM3 GNAS JMJD1C

7.36e-04106493EFO_0803544
Diseaseresponse to norepinephrine-dopamine reuptake inhibitor

ABLIM1 ROBO2

8.56e-0426492EFO_0007870
Diseaseimmature platelet fraction

DNM3 GNAS JMJD1C

9.09e-04114493EFO_0009187
DiseaseAutistic Disorder

TAF1C ROBO2 CACNA1H JMJD1C

9.27e-04261494C0004352
Diseasecolorectal cancer (implicated_via_orthology)

NOTCH1 NOTCH3

1.14e-0330492DOID:9256 (implicated_via_orthology)
Diseasemigraine disorder, glucose measurement

CACNA1H JMJD1C

1.22e-0331492EFO_0004468, MONDO_0005277
Diseaseintestinal cancer (implicated_via_orthology)

NOTCH1 NOTCH3

1.30e-0332492DOID:10155 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
EPPSWPSPTEDPTGH

UMODL1

641

Q5DID0
PSAQHSWSPEPSVVP

GNAS

71

P84996
PNSVTPTTHQGPWEE

ATG16L2

61

Q8NAA4
PDPSETPKIETDHWP

ABLIM1

556

O14639
EPSQDSPHSDKWPPG

B4GALNT3

521

Q6L9W6
PHWENSPSPLPSVTG

GJA10

461

Q969M2
AGPPTTDPWALNSPH

EPN3

381

Q9H201
TGQPWPLDPENSHEP

ADAM33

771

Q9BZ11
HFPTWPELGLPDSPS

PTPN23

1351

Q9H3S7
SHAAPGPSPDSWVPR

FCHO1

481

O14526
PNDGWAESEVPPSPT

PARD3B

646

Q8TEW8
EHPFLTPSPESPDQW

NOTCH1

2506

P46531
PAPESHTPAPFSWGT

MAP1A

1866

P78559
PQSPPEWEDSLSPLH

MAGEC1

711

O60732
EVDSPGETPSWAPQP

KIAA1671

1741

Q9BY89
PSPWLHQPTPVTSAD

JMJD1C

901

Q15652
STPAPPPVDDSWIQH

DNM3

751

Q9UQ16
PHAWSDPSDPLPVSV

KIR3DL3

301

Q8N743
SPHPSWETDTVPCPV

RASGRP4

646

Q8TDF6
TPSPESPEHWASPSP

NOTCH3

2246

Q9UM47
PAPEGPHQVPQSSWE

MROH6

91

A6NGR9
EETPPSPWVIHPNDV

DRC1

611

Q96MC2
ESSVILSWSPPPHGE

OBSCN

526

Q5VST9
PSSSPTDPEWFGDEH

PROX2

46

Q3B8N5
SPPSGHQPVSDWGEE

CCDC9

491

Q9Y3X0
DGPSHSQAPSPWLTP

DENND4B

1326

O75064
PAPFGDQSHPEPESW

ECM1

131

Q16610
WQPTAEPHGPEASPV

CACNA1H

2111

O95180
FTAWPDHGVPEHPTP

PTPRD

1516

P23468
AHSAPQPLWTDEAPP

USH2A

4141

O75445
HSPPPPQENWVSFAD

REPS1

221

Q96D71
ETEHWPPGQESPTSP

SSPOP

2306

A2VEC9
PDSATDPTSPQPHNW

TMEM132A

881

Q24JP5
EAWPPVGTPPSSESE

HCLS1

301

P14317
DTSSPHSPEWPPADA

TAF1C

771

Q15572
PLPSPVWETHTDAGT

ARHGAP27

246

Q6ZUM4
EPHPPGEGPSEWSSD

RNF43

736

Q68DV7
PQPPSEGPITHQWSV

ITGAL

976

P20701
GVIPSSPEEWPESPT

SMTNL1

266

A8MU46
SPEEWPESPTGEGHN

SMTNL1

271

A8MU46
GSDLGHWVTTPPDIP

SLC25A46

36

Q96AG3
WEPGAVPPSTEHLDP

SLC27A4

206

Q6P1M0
PPEWDSVPVHKPGSS

TMEM131

1561

Q92545
PEWTPEPRSSSSQHP

PRRC2B

916

Q5JSZ5
ISVSWDPPPPDHQNG

ROBO2

756

Q9HCK4
WPVVPPEEHSSFAPD

TET3

406

O43151
VPSHPQDPQGPSLEW

NDUFA3

66

O95167
TNTTPWEHPYPDLPS

TRIM16

396

O95361
SEEDEWAVPTSPPSP

TBKBP1

521

A7MCY6
VEEEPGWPHPQSCST

MYRIP

256

Q8NFW9