Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscell cycle process

BLM FANCD2 DACT1 SETD2 MCMBP CTC1 ANXA11 BTBD18 GOLGA8B CEP152 CEP192 CEP126 CUL7 SMC5 BIRC6 GOLGA2

1.10e-0514416716GO:0022402
GeneOntologyBiologicalProcessGolgi ribbon formation

MYO18A GOLGA8B GOLGA2

5.54e-0523673GO:0090161
GeneOntologyCellularComponentprocentriole

CEP152 CEP192

3.03e-053672GO:0120098
GeneOntologyCellularComponentprocentriole replication complex

CEP152 CEP192

1.51e-046672GO:0120099
DomainGOLGA2L5

GOLGA8B GOLGA2

1.81e-0318662PF15070
DomainGolgin_A

GOLGA8B GOLGA2

1.81e-0318662IPR024858
DomainZZ

DYTN MIB2

1.81e-0318662PF00569
DomainZF_ZZ_2

DYTN MIB2

1.81e-0318662PS50135
DomainZF_ZZ_1

DYTN MIB2

1.81e-0318662PS01357
DomainZnf_ZZ

DYTN MIB2

2.02e-0319662IPR000433
DomainZnF_ZZ

DYTN MIB2

2.02e-0319662SM00291
DomainDAPIN

NLRP11 NLRP14

2.71e-0322662PS50824
DomainPYRIN

NLRP11 NLRP14

2.71e-0322662PF02758
DomainDAPIN

NLRP11 NLRP14

2.71e-0322662IPR004020
DomainPYRIN

NLRP11 NLRP14

2.71e-0322662SM01289
DomainP-loop_NTPase

BLM DNHD1 ABCC4 NLRP14 KIF26B ABCB8 MYO18A SMC5 ATAD2

2.85e-03848669IPR027417
DomainNACHT

NLRP11 NLRP14

2.97e-0323662PS50837
DomainNACHT_NTPase

NLRP11 NLRP14

2.97e-0323662IPR007111
DomainABC_membrane

ABCC4 ABCB8

3.23e-0324662PF00664
DomaintRNA-bd_arm

DSP CEP152

3.23e-0324662IPR010978
DomainABC_TM1F

ABCC4 ABCB8

4.38e-0328662PS50929
DomainABC1_TM_dom

ABCC4 ABCB8

4.38e-0328662IPR011527
Domain-

BLM DNHD1 ABCC4 NLRP14 ABCB8 MYO18A SMC5 ATAD2

4.63e-037466683.40.50.300
DomainSpectrin_repeat

SPTBN5 DSP

4.70e-0329662IPR002017
DomainSpectrin/alpha-actinin

SPTBN5 DSP

5.70e-0332662IPR018159
DomainSPEC

SPTBN5 DSP

5.70e-0332662SM00150
Pubmed

BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks.

BLM FANCD2

3.66e-06267215257300
Pubmed

FANCD2 limits BLM-dependent telomere instability in the alternative lengthening of telomeres pathway.

BLM FANCD2

3.66e-06267227427384
Pubmed

An actin-WHAMM interaction linking SETD2 and autophagy.

SETD2 WHAMM

3.66e-06267233036756
Pubmed

Distinct roles of Cep192 and Cep152 in acentriolar MTOCs and spindle formation during mouse oocyte maturation.

CEP152 CEP192

3.66e-06267228970258
Pubmed

SEDT2/METTL14-mediated m6A methylation awakening contributes to hypoxia-induced pulmonary arterial hypertension in mice.

SETD2 METTL14

3.66e-06267233658391
Pubmed

Desmoplakin is involved in organization of an adhesion complex in peripheral nerve regeneration after injury.

MNX1 DSP

3.66e-06267225496840
Pubmed

Leucine-rich repeat-containing protein 59 mediates nuclear import of cancerous inhibitor of PP2A in prostate cancer cells.

CEP152 CEP192 SMC5

3.76e-061667325833693
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MYCL DACT1 CTC1 CDK13 CSAD ANXA11 OBSCN LAMC3 MIB2 CEP192 BIRC6

7.99e-061105671135748872
Pubmed

Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152.

CEP152 CEP192

1.10e-05367224277814
Pubmed

Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication.

CEP152 CEP192

1.10e-05367223641073
Pubmed

STIL binding to Polo-box 3 of PLK4 regulates centriole duplication.

CEP152 CEP192

2.19e-05467226188084
Pubmed

Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.

CEP152 CEP192

2.19e-05467224997597
Pubmed

FANCD2-controlled chromatin access of the Fanconi-associated nuclease FAN1 is crucial for the recovery of stalled replication forks.

BLM FANCD2

2.19e-05467225135477
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

CEP152 CEP192 CUL7 BIRC6 SNRPD2 FUBP3 RASAL2

2.44e-0544667724255178
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

BLM FANCD2 MCMBP DSP CCDC18 CEP192 CUL7 BIRC6 SNRPD2 C19orf25

3.11e-051049671027880917
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

SPTBN5 DNHD1 SETD2 MYO18A EPX

3.14e-0518767526460568
Pubmed

The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route.

SPTBN5 GOLGA8B GOLGA2

3.26e-053267323704327
Pubmed

A Japanese-specific allele in the GALNT11 gene.

ABCC4 CEP152

3.64e-05567220547088
Pubmed

Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.

DSP ABCB8 OBSCN MYO18A DLST RYR2

4.35e-0533167629199018
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SETD2 CDK13 SOCS5 CEP152 CUL7 PRORP BIRC6

4.60e-0549367715368895
Pubmed

Hepatitis C virus infection protein network.

SETD2 GOLGA2 RASAL2

7.43e-054267318985028
Pubmed

Rbx2 regulates neuronal migration through different cullin 5-RING ligase adaptors.

SOCS5 GOLGA8B GOLGA2

7.43e-054267324210661
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

FANCD2 DNHD1 MCMBP DSP DLST LAMC3 SNRPA1 ATAD2 SNRPD2 FUBP3 RASAL2

8.19e-051425671130948266
Pubmed

BCAS2 regulates oocyte meiotic prophase I by participating in mRNA alternative splicing.

FANCD2 GOLGA8B GOLGA2

8.55e-054467338085152
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

BLM CDK13 MYO18A DLST CUL7 SMC5 BIRC6 SNRPD2

1.04e-0475967835915203
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

BLM FANCD2 SETD2 DSP CDK13 MYO18A ATAD2 ARHGEF6

1.19e-0477467815302935
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

BLM SETD2 MCMBP DSP CEP192 CUL7 GOLGA2

1.38e-0458867738580884
Pubmed

Stimulatory effect of splicing factors on transcriptional elongation.

SNRPA1 SNRPD2

1.63e-041067211780068
Pubmed

Arrhythmogenic Right Ventricular Cardiomyopathy Overview

DSP RYR2

1.63e-041067220301310
Pubmed

Fance deficiency inhibits primordial germ cell proliferation associated with transcription-replication conflicts accumulate and DNA repair defects.

BLM FANCD2

1.63e-041067237563658
Pubmed

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA.

DSP SNRPA1 SNRPD2

1.95e-045867321642987
Pubmed

The leucine zipper putative tumor suppressor 2 protein LZTS2 regulates kidney development.

LZTS3 LZTS1

1.99e-041167221949185
Pubmed

Cardiac disease and arrhythmogenesis: Mechanistic insights from mouse models.

DSP RYR2

1.99e-041167227766308
Pubmed

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M.

BLM FANCD2

2.38e-041267216116422
Pubmed

A novel ubiquitin ligase is deficient in Fanconi anemia.

BLM FANCD2

2.38e-041267212973351
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

BLM FANCD2 SETD2 CTC1 ANXA11 SMC5

2.41e-0445367629656893
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

BLM FANCD2 DSP DLST ATAD2 SNRPD2 FUBP3

2.59e-0465267731180492
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

BLM DSP ANXA11 CUL7 ATAD2 BIRC6 FUBP3

2.61e-0465367722586326
Pubmed

Single-cell RNA-Seq reveals a highly coordinated transcriptional program in mouse germ cells during primordial follicle formation.

NLRP14 GOLGA8B GOLGA2

2.62e-046467334174788
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

FANCD2 DSP ITM2C SNRPA1 BIRC6 SNRPD2 GOLGA2

2.71e-0465767736180527
Pubmed

Ftm is a novel basal body protein of cilia involved in Shh signalling.

MNX1 PITX2

2.81e-041367217553904
Pubmed

GM130 regulates pulmonary surfactant protein secretion in alveolar type II cells.

GOLGA8B GOLGA2

2.81e-041367233740186
Pubmed

Loss of GM130 does not impair oocyte meiosis and embryo development in mice.

GOLGA8B GOLGA2

2.81e-041367232873390
Pubmed

GM130, a cis-Golgi protein, regulates meiotic spindle assembly and asymmetric division in mouse oocyte.

GOLGA8B GOLGA2

2.81e-041367221552007
Pubmed

GOLGA2 loss causes fibrosis with autophagy in the mouse lung and liver.

GOLGA8B GOLGA2

2.81e-041367229128360
Pubmed

Globozoospermia and lack of acrosome formation in GM130-deficient mice.

GOLGA8B GOLGA2

2.81e-041367228055014
Pubmed

Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice.

GOLGA8B GOLGA2

2.81e-041367228028212
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

LZTS3 DSP MYO18A DLST ITM2C MIB2 SNRPA1 BIRC6 RYR2

3.26e-04113967936417873
Pubmed

GM130 and p115 play a key role in the organisation of the early secretory pathway during skeletal muscle differentiation.

GOLGA8B GOLGA2

3.28e-041467230630895
Pubmed

Golgb1 regulates protein glycosylation and is crucial for mammalian palate development.

GOLGA8B GOLGA2

3.28e-041467227226319
Pubmed

The genetics of NOD-like receptors in Crohn's disease.

NLRP11 NLRP14

3.28e-041467220403135
Pubmed

NALPs: a novel protein family involved in inflammation.

NLRP11 NLRP14

3.28e-041467212563287
Pubmed

Cdk1 protects against oxygen-glucose deprivation and reperfusion-induced Golgi fragmentation and apoptosis through mediating GM130 phosphorylation.

GOLGA8B GOLGA2

3.28e-041467237831422
Pubmed

Oligoasthenoteratospermia and sperm tail bending in PPP4C-deficient mice.

GOLGA8B GOLGA2

3.28e-041467233543287
Pubmed

CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion.

CEP152 CEP192

3.28e-041467232060285
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

LZTS3 KIF26B CROCC2 DLST PRORP SNRPD2 RASAL2

3.61e-0468967736543142
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

BLM CTC1 CEP152 CEP192 SMC5 SNRPA1 SNRPD2 GOLGA2 C19orf25

3.61e-04115567920360068
Pubmed

The a3 isoform of V-ATPase regulates insulin secretion from pancreatic beta-cells.

GOLGA8B GOLGA2

3.78e-041567217046993
Pubmed

GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules.

GOLGA8B GOLGA2

3.78e-041567226165940
Pubmed

Mouse oocytes within germ cell cysts and primordial follicles contain a Balbiani body.

GOLGA8B GOLGA2

3.78e-041567217189423
Pubmed

Calumin, a novel Ca2+-binding transmembrane protein on the endoplasmic reticulum.

GOLGA8B GOLGA2

3.78e-041567217204322
Pubmed

RhoA-mediated FMNL1 regulates GM130 for actin assembly and phosphorylates MAPK for spindle formation in mouse oocyte meiosis.

GOLGA8B GOLGA2

3.78e-041567226083584
Pubmed

Demonstration of the expression and the enzymatic activity of N-acetylglucosaminyltransferase IX in the mouse brain.

GOLGA8B GOLGA2

3.78e-041567216413118
Pubmed

WDR38, a novel equatorial segment protein, interacts with the GTPase protein RAB19 and Golgi protein GM130 to play roles in acrosome biogenesis.

GOLGA8B GOLGA2

3.78e-041567237635409
Pubmed

Golgi disruption and early embryonic lethality in mice lacking USO1.

GOLGA8B GOLGA2

3.78e-041567223185636
Pubmed

Golga5 is dispensable for mouse embryonic development and postnatal survival.

GOLGA8B GOLGA2

3.78e-041567228509431
Pubmed

The protein interaction landscape of the human CMGC kinase group.

FANCD2 SETD2 LZTS3 CDK13 PRKG2 CUL7 GOLGA2

3.80e-0469567723602568
Pubmed

A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.

BLM FANCD2 ALDH3B1 SNRPD2

4.12e-0418067424104479
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

BLM MCMBP CDK13 SNRPA1 GOLGA2 ARHGEF6

4.20e-0450367616964243
Pubmed

Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair.

FANCD2 SNRPA1

4.31e-041667231980815
Pubmed

LIM kinase 2 is widely expressed in all tissues.

GOLGA8B GOLGA2

4.31e-041667216399995
Pubmed

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development.

MNX1 PITX2

4.31e-041667215843409
Pubmed

Molecular characterization of mitocalcin, a novel mitochondrial Ca2+-binding protein with EF-hand and coiled-coil domains.

GOLGA8B GOLGA2

4.31e-041667216336229
Pubmed

SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-calcium exchange activity that regulates human epidermal melanogenesis.

GOLGA8B GOLGA2

4.31e-041667218166528
Pubmed

Molecular motor KIF1C is not essential for mouse survival and motor-dependent retrograde Golgi apparatus-to-endoplasmic reticulum transport.

GOLGA8B GOLGA2

4.31e-041667211784862
Pubmed

SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis.

FANCD2 SMC5

4.31e-041667233200984
Pubmed

p125/Sec23-interacting protein (Sec23ip) is required for spermiogenesis.

GOLGA8B GOLGA2

4.31e-041667221640725
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

DSP MYO18A DLST SNRPA1 SNRPD2 FUBP3 GOLGA2

4.35e-0471167733022573
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

DSP CEP152 CEP192 RASAL2

4.48e-0418467432908313
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

BLM SETD2 DSP ANXA11 SMC5 SNRPA1 SNRPD2 FUBP3

4.86e-0495467836373674
Pubmed

Phospholipase D2 localizes to the plasma membrane and regulates angiotensin II receptor endocytosis.

GOLGA8B GOLGA2

4.88e-041767214718562
Pubmed

The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A.

GOLGA8B GOLGA2

4.88e-041767227655914
Pubmed

Vesicle budding from endoplasmic reticulum is involved in calsequestrin routing to sarcoplasmic reticulum of skeletal muscles.

GOLGA8B GOLGA2

4.88e-041767214728599
Pubmed

Dynamics and function of CXCR4 in formation of the granule cell layer during hippocampal development.

GOLGA8B GOLGA2

4.88e-041767228717168
Pubmed

A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly.

GOLGA8B GOLGA2

4.88e-041767220004763
Pubmed

Increased β-catenin activity in the anterior neural plate induces ectopic mid-hindbrain characteristics.

ABCC4 WFDC1

4.88e-041767222102609
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

LZTS1 CROCC2 DLST SNRPA1 SNRPD2 FUBP3 SPINK5

5.17e-0473267734732716
Pubmed

Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis.

GOLGA8B GOLGA2

5.48e-041867221147753
Pubmed

p115 Interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation.

GOLGA8B GOLGA2

5.48e-041867215800058
Pubmed

N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration.

GOLGA8B GOLGA2

5.48e-041867224227724
Pubmed

Altered GLUT4 trafficking in adipocytes in the absence of the GTPase Arfrp1.

GOLGA8B GOLGA2

5.48e-041867220230794
Pubmed

Flightless, secreted through a late endosome/lysosome pathway, binds LPS and dampens cytokine secretion.

GOLGA8B GOLGA2

5.48e-041867222718342
Pubmed

Protein kinase LKB1 regulates polarized dendrite formation of adult hippocampal newborn neurons.

GOLGA8B GOLGA2

5.48e-041867224367100
Pubmed

Scrib:Rac1 interactions are required for the morphogenesis of the ventricular myocardium.

DSP ARHGEF6

5.48e-041867225139745
Pubmed

Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2.

GOLGA8B GOLGA2

5.48e-041867220943658
Pubmed

Yip1B isoform is localized at ER-Golgi intermediate and cis-Golgi compartments and is not required for maintenance of the Golgi structure in skeletal muscle.

GOLGA8B GOLGA2

5.48e-041867225208654
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

BLM FANCD2 SPTBN5 CDK13 DLST CUL7 PRORP BIRC6 FUBP3 C19orf25

5.58e-041496671032877691
Pubmed

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

CIAO3 SOCS5 ADAMTSL3 FUBP3

5.90e-0419867420881960
Pubmed

SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells.

GOLGA8B GOLGA2

6.12e-041967223444373
Pubmed

Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brain.

GOLGA8B GOLGA2

6.12e-041967212646573
InteractionKRT18 interactions

FANCD2 DSP CCDC18 CEP152 CEP192 CUL7 SMC5 BIRC6 GOLGA2 METTL14

1.17e-064196710int:KRT18
InteractionTNRC6C interactions

DSP CCDC18 DLST MIB2 CEP192 FUBP3

6.55e-06138676int:TNRC6C
InteractionPRKDC interactions

FANCD2 DSP MYO18A DLST LAMC3 CUL7 SMC5 SNRPA1 SNRPD2 ARHGEF6 METTL14

1.68e-056956711int:PRKDC
InteractionKRT19 interactions

FANCD2 DSP CCDC18 CEP152 CEP192 BIRC6 DGCR6L

4.14e-05282677int:KRT19
InteractionICE1 interactions

FANCD2 SMC5 SNRPA1 GOLGA2

4.42e-0559674int:ICE1
InteractionLZTS2 interactions

LZTS3 CTC1 DSP LZTS1 MYO18A CEP152 CEP192 BIRC6 DGCR6L

4.75e-05512679int:LZTS2
InteractionPRPF3 interactions

FANCD2 LZTS1 CDK13 SMC5 SNRPA1 SNRPD2 GOLGA2

5.05e-05291677int:PRPF3
InteractionCEP128 interactions

LZTS3 DSP CCDC18 CEP152 MIB2 CEP192 RASAL2

5.74e-05297677int:CEP128
InteractionPNN interactions

FANCD2 DLST CUL7 SMC5 SNRPA1 BIRC6 SNRPD2

6.38e-05302677int:PNN
InteractionRYR3 interactions

DSP RYR2 METTL14

6.76e-0524673int:RYR3
InteractionANXA2 interactions

FANCD2 DSP ANXA11 MYO18A DLST CUL7 SMC5 METTL14

7.29e-05419678int:ANXA2
InteractionFAM184A interactions

CCDC18 CEP192 CUL7 GOLGA2

9.68e-0572674int:FAM184A
InteractionRIF1 interactions

BLM FANCD2 CTC1 CEP126 CUL7 SMC5

1.02e-04225676int:RIF1
InteractionVPS37C interactions

FANCD2 ZDHHC23 RIBC1 GOLGA2 ARHGEF6

1.06e-04141675int:VPS37C
InteractionTHRAP3 interactions

FANCD2 DLST CEP126 CUL7 SMC5 SNRPA1 SNRPD2 METTL14

1.07e-04443678int:THRAP3
InteractionDDX46 interactions

MYO18A CUL7 SMC5 SNRPA1 SNRPD2 METTL14

1.08e-04227676int:DDX46
InteractionPRPF19 interactions

FANCD2 CCDC18 DLST CEP192 CUL7 SMC5 SNRPA1 SNRPD2

1.20e-04450678int:PRPF19
InteractionXRCC2 interactions

BLM FANCD2 WFDC1

1.21e-0429673int:XRCC2
InteractionDEUP1 interactions

CEP152 CEP192 DGCR6L GOLGA2

1.26e-0477674int:DEUP1
InteractionRRBP1 interactions

FANCD2 MNX1 DSP DLST CUL7 SMC5 BIRC6

1.36e-04341677int:RRBP1
InteractionEEF1G interactions

FANCD2 LZTS1 DLST CUL7 SMC5 SNRPA1 SNRPD2 METTL14

1.45e-04463678int:EEF1G
InteractionNUMA1 interactions

FANCD2 MCMBP RIBC1 DLST CUL7 SMC5 ATAD2 BIRC6

1.59e-04469678int:NUMA1
InteractionARL16 interactions

BLM CEP192 BIRC6 GOLGA2

1.68e-0483674int:ARL16
InteractionKAT5 interactions

FANCD2 MYCL LZTS1 PITX2 CEP126 SNRPD2 GOLGA2

1.83e-04358677int:KAT5
InteractionMISP interactions

FANCD2 ZDHHC23 MYO18A RIBC1 GOLGA2

2.16e-04164675int:MISP
InteractionPUF60 interactions

FANCD2 MYO18A CUL7 SMC5 SNRPA1 SNRPD2 METTL14

2.21e-04369677int:PUF60
Cytoband7q36

MNX1 ABCB8

7.19e-04276727q36
CytobandEnsembl 112 genes in cytogenetic band chr7q36

MNX1 ABCB8 ZNF786

1.66e-03159673chr7q36
Cytoband15q25.2

WHAMM ADAMTSL3

1.82e-034367215q25.2
Cytoband9q34.11

FUBP3 GOLGA2

2.76e-03536729q34.11
GeneFamilyLeucine zipper tumor suppressor family

LZTS3 LZTS1

3.46e-0544421314
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DYTN MIB2

8.64e-041844291
GeneFamilyNLR family

NLRP11 NLRP14

1.68e-0325442666
GeneFamilyPyrin domain containing|Pyrin and HIN domain family

NLRP11 NLRP14

1.68e-0325442994
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000

BLM FANCD2 ABCC4 ZDHHC23 CCDC18 CEP192 PRORP ATAD2

9.81e-06333678gudmap_dev gonad_e13.5_M_GermCell_Oct_k1_1000
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#4_top-relative-expression-ranked_500

BLM FANCD2 ZDHHC23 CCDC18 CEP192

1.68e-05101675gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k4_500
ToppCellnormal_Lung-Fibroblasts-Pericytes|normal_Lung / Location, Cell class and cell subclass

CD248 LZTS1 OBSCN WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

3.13e-10181678f74941e49950027360d71ea3b205fc20c6929766
ToppCellBronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CD248 LZTS1 OBSCN WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

6.90e-1020067812326cc6f0af24bacba9493dc79e7c7347db2f41
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

DACT1 CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

6.90e-102006788c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellBronchial-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CD248 LZTS1 OBSCN WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

6.90e-10200678362706445edb33b313684efe50b1f44f5f816e67
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_only / Treatment groups by lineage, cell group, cell type

ABCC4 CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

6.90e-1020067869edc375d85689300d1dbc1217fedc40063ecdcb
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

CD248 LZTS1 OBSCN WFDC1 LAMC3 ADAMTSL3 RYR2

1.45e-08189677d7ed96add29f219183c802895fbff519b627f635
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LZTS1 OBSCN WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

1.56e-081916771626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LZTS1 OBSCN WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

1.56e-08191677716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LZTS1 KIF26B OBSCN WFDC1 LAMC3 ADAMTSL3 RYR2

1.74e-081946772d66091097e106c7bee22e5281f50724700bdf8d
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

LZTS1 OBSCN WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

2.14e-082006770c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

2.14e-082006774e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DACT1 CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

2.14e-08200677cf883ba5dbe6350b93142d625a52b25ff2a8bb63
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DACT1 CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

2.14e-08200677b22cae282591d8dead9869c2adbb9632615f50f7
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LZTS1 OBSCN WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

2.14e-08200677522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellcritical-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

BLM MYCL MCMBP CCDC18 CEP152 SMC5 ATAD2

2.14e-08200677f39db4250ce220a3eb58edee3f7fc3671701d46f
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

2.14e-08200677786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LZTS1 OBSCN WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

2.14e-0820067794f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCelldistal-mesenchymal-Pericyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 LZTS1 OBSCN WFDC1 LAMC3 ITM2C ADAMTSL3

2.14e-08200677867935701fac71a3fe01578362da0676f959736c
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte|Control_saline / Treatment groups by lineage, cell group, cell type

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

2.14e-08200677cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

2.14e-08200677bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD248 LZTS1 WFDC1 LAMC3 ADAMTSL3 RYR2

1.37e-07157676bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCellnormal_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

LZTS1 OBSCN WFDC1 LAMC3 ITM2C RASAL2

2.20e-07170676d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

LZTS1 OBSCN WFDC1 LAMC3 ADAMTSL3 RYR2

2.27e-07171676080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

MNX1 LZTS1 WFDC1 LAMC3 ADAMTSL3 RYR2

2.35e-07172676858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCellAdult-Mesenchymal-pericyte_cell-D175|Adult / Lineage, Cell type, age group and donor

LZTS1 OBSCN WFDC1 LAMC3 ADAMTSL3 RYR2

2.43e-07173676fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LZTS1 OBSCN WFDC1 LAMC3 ADAMTSL3 RYR2

2.88e-07178676185b44700f06ec58b3c09c80520502166c965fd6
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD248 LZTS1 WFDC1 LAMC3 ADAMTSL3 RYR2

3.39e-071836768a799807fbf24456a9811e0c64068187940a2f71
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

LZTS1 OBSCN WFDC1 LAMC3 ADAMTSL3 RYR2

3.39e-07183676fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD248 LZTS1 WFDC1 LAMC3 ADAMTSL3 RYR2

3.50e-07184676689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellCOPD-Stromal-Pericyte|COPD / Disease state, Lineage and Cell class

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

3.50e-07184676a56264a22dfc2d3672b20134ab7c3c7c23da5ae1
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

3.50e-07184676102b6f621a5b551e622f97b12d787c080b052a72
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 CD248 LZTS1 LAMC3 ADAMTSL3 RYR2

3.50e-07184676327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

BLM FANCD2 GALNT14 CCDC18 CEP152 ATAD2

3.61e-071856769766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

LZTS1 WFDC1 LAMC3 ADAMTSL3 RASAL2 RYR2

3.61e-071856764905adaeeffd353e089578e5ea614437dbe794e6
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LZTS1 OBSCN WFDC1 LAMC3 ADAMTSL3 RYR2

3.73e-07186676888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellCOPD-Stromal-Pericyte|World / Disease state, Lineage and Cell class

LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

3.73e-071866768adfd2d1fda4e8aecc95192ea627bf7ed5214b8d
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

LZTS1 OBSCN WFDC1 LAMC3 ADAMTSL3 RYR2

3.85e-0718767662759efb660179402fb574ce5701c89a2e17bcfe
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD248 OBSCN WFDC1 LAMC3 ITM2C ADAMTSL3

3.85e-071876768ee3bf885897efd634c3a0567637142a9f55e693
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CD248 LZTS1 OBSCN LAMC3 ADAMTSL3 RYR2

3.85e-07187676a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CD248 LZTS1 OBSCN WFDC1 LAMC3 ADAMTSL3

3.97e-07188676ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

LZTS1 OBSCN WFDC1 LAMC3 ADAMTSL3 RYR2

3.97e-07188676ee151792c7ac9afe820f1a281c6dab383799f358
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LZTS1 OBSCN WFDC1 LAMC3 ADAMTSL3 RYR2

4.22e-071906764eb92aef1ee868f4537483d19014d947b7684612
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LZTS1 OBSCN WFDC1 LAMC3 ADAMTSL3 RYR2

4.22e-071906767be4341e2909101d756f14031c21e705eb45e69a
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

BLM FANCD2 CCDC18 CEP152 CEP192 ATAD2

4.22e-07190676d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

4.77e-071946768f19e553f18c313c2a2ff9453884b9484b255d71
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

4.77e-0719467667fbb81b7d20cb63be27b2a2beea5b5689f8e08c
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

4.77e-07194676f95935153bd2c4c3c7b2b729da6f7e98b45fed79
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.06e-07196676c373465e34e2dd581247962d59e0477aae877079
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.06e-071966769d18381d7aaa063094a5df769a04c73350471525
ToppCellIPF-Stromal-Pericyte|IPF / Disease state, Lineage and Cell class

LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

5.06e-071966768b6ff47ce5291d223f5e639fc45cd9267f418256
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.06e-071966768b5337ccf74de90e8b89a02ac00671af1de2cfff
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.06e-07196676a52cb512c6173be92aa9c4d96e2abbc32f45478d
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.06e-07196676afddacc0fb8b9c73dad5333137deb471a6ebdc06
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LZTS1 OBSCN WFDC1 LAMC3 ADAMTSL3 RYR2

5.22e-07197676f66945f9007d59d4208849c7fd727f8519713fbc
ToppCellParenchymal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LZTS1 OBSCN WFDC1 LAMC3 ADAMTSL3 RYR2

5.22e-0719767641dd312f46a2b983c8d864adeb6970c0ca4a8048
ToppCelldistal-2-mesenchymal-Vascular_Smooth_Muscle|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DACT1 LZTS1 WFDC1 ITM2C ADAMTSL3 RYR2

5.37e-07198676ce05ede69c167b2294630709bb0c223483a6ef75
ToppCellBronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LZTS1 OBSCN LAMC3 ADAMTSL3 RASAL2 RYR2

5.54e-07199676929f809579368201331d9099d8904b6e3c41797b
ToppCelldistal-mesenchymal-Pericyte-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.54e-07199676e72ac7a00405cde06293d7adac7dc40eb0cf87ba
ToppCellBronchial-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LZTS1 OBSCN LAMC3 ADAMTSL3 RASAL2 RYR2

5.54e-07199676854628ce91068093c14bd4d45ba38c41469f3549
ToppCellmedial-mesenchymal-Pericyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-07200676bbda454260016be92b539e220ecf7bcbbc6139e4
ToppCellproximal-3-mesenchymal-Pericyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-0720067698cbd0f4994e645f70c0bc5ebc1c3a3b28c6b67f
ToppCelldistal-3-mesenchymal-Pericyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-07200676911db29f254bb697610e720ba78816e2c7f57933
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-07200676b5b5a32925f225610fe25a021a742d6397162863
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-07200676d2fcd3bd7c3223875f027eeb48ff621192a5f242
ToppCellmedial-mesenchymal-Pericyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-07200676f36d7cb6345daccebf76997f998e35d959b59452
ToppCelldistal-2-mesenchymal|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-0720067665a50f03b0027ccefb51b8f77afa283d4a3b3567
ToppCelldistal-mesenchymal-Pericyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-07200676fe31287cfb51d45643bdedbaa5efc03ed87263c6
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

5.70e-072006768158f4eaeff945a6788c8e732b7a1b0d78052a06
ToppCellBiopsy_Other_PF-Mesenchymal-Smooth_Muscle_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-0720067655ac281901309e30978da1f7489386e54489721e
ToppCellmedial-2-mesenchymal-Pericyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-072006769820fb4f6efcdfc6de937ef2302a98b48426baa3
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3 RYR2

5.70e-07200676600d56257b1b0cda8ed2fd0db92c6551711f7d6d
ToppCellParenchymal-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-07200676f9bc22ff17bb1c751e6b05bca3f403836f33459a
ToppCelldistal-1-mesenchymal-Pericyte|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-07200676ff205afda57b9267016f0c937445da1b0266af9b
ToppCellproximal-mesenchymal-Pericyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-0720067603119a979bc912a98e6fc87addcbc25d8ecf2fb0
ToppCellParenchymal-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-072006760a7640db28c708003d5da2d19eb651f6fedfd710
ToppCelldistal-2-mesenchymal-Pericyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-072006764ee0b2f56c2652435fa78bf6b3c90cea28df74e0
ToppCellLPS_IL1RA-Mesenchymal_myocytic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DACT1 CD248 LZTS1 WFDC1 ITM2C ADAMTSL3

5.70e-0720067677631c471cc5d453a749784f838cfa6408caf09b
ToppCellproximal-mesenchymal-Pericyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 LZTS1 WFDC1 LAMC3 ITM2C ADAMTSL3

5.70e-07200676a81fde3d40b8efb3be535aeb2a44cfbdeb17bc8b
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Nxph2_Sla|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FANCD2 SPTBN5 ABCC4 ZDHHC23 OBSCN

1.81e-061346756d97fa07f55ae20c17b9d5262e893957cccc6dba
ToppCellE16.5-samps-Mesenchymal-Pericyte|E16.5-samps / Age Group, Lineage, Cell class and subclass

DACT1 PRORP ADAMTSL3 ZNF786 ARHGEF6

2.95e-06148675e697a7fb037873c9b11703d1bf836a69fc276e23
ToppCellE16.5-samps-Mesenchymal-Pericyte-pericyte_A|E16.5-samps / Age Group, Lineage, Cell class and subclass

DACT1 PRORP ADAMTSL3 ZNF786 ARHGEF6

2.95e-06148675c87fe2373418ec0cfe37279003d1c4df4c0d0aac
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPTBN5 ABCC4 ANXA11 PRKG2 ALDH3B1

2.95e-06148675d5cace5605bff2bb8248fadb51f2dad7539930ba
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LZTS1 WFDC1 LAMC3 ADAMTSL3 RYR2

3.82e-061566756365b69ede98bc866e996bc52736b00401aacf6f
ToppCellCOVID-CD8-CD8_2|COVID / Condition, Cell_class and T cell subcluster

CD248 LZTS1 ITM2C SNRPD2 RYR2

4.45e-06161675307dcc17475413cd9eb70c27bc447f938ee5723d
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FANCD2 SPTBN5 ZDHHC23 LZTS1 OBSCN

4.59e-0616267558da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DACT1 CD248 LZTS1 WFDC1 RYR2

5.32e-06167675e228b8373ffd4436e6b944e26d0fadf3ac289b21
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DACT1 CD248 LZTS1 WFDC1 RYR2

5.32e-061676757cb1b11e8e24a10115e46ffbb74889e672a7a026
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DACT1 CD248 LZTS1 WFDC1 RYR2

5.32e-06167675bb53a478b5d821d6d82c15bc4ed075b67682457c
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Col27a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FANCD2 SPTBN5 GALNT14 ABCC4 ANXA11

5.97e-06171675d07e2c5f7d7f12c68860d4161d76372de174f1d8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BLM FANCD2 BTBD18 CEP152 ATAD2

5.97e-06171675c2dbc439af28d4fabb24d57685b75b2e588819b0
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP CDK13 PITX2 MYO18A PRKG2

6.32e-06173675e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCellfacs-Large_Intestine-Proximal-3m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP CDK13 PITX2 MYO18A PRKG2

6.32e-0617367599532bb768ee35fed939a377acb5215d3f8904bd
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LZTS1 OBSCN WFDC1 LAMC3 ADAMTSL3

7.45e-06179675dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DACT1 LZTS3 CD248 CUL7 ADAMTSL3

7.66e-06180675c4068fe47408cfd899131a85fa4b7e5908926f94
ToppCell21-Trachea-Epithelial-Multiciliated_precursor|Trachea / Age, Tissue, Lineage and Cell class

MYCL ZDHHC23 RIBC1 CEP152 CEP126

8.08e-061826756e35892fa959ee31591850ded8f1088195ddeb01
ToppCelltumor_Lung-Fibroblasts-Pericytes|tumor_Lung / Location, Cell class and cell subclass

CD248 LZTS1 WFDC1 LAMC3 ADAMTSL3

8.30e-06183675a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BLM FANCD2 CCDC18 CEP152 ATAD2

8.75e-0618567530e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

LZTS1 OBSCN LAMC3 ADAMTSL3 RYR2

9.21e-0618767586250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BLM FANCD2 CCDC18 CEP152 ATAD2

9.21e-061876759351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

CD248 LZTS1 LAMC3 ITM2C ADAMTSL3

9.70e-061896759c407b17d7945e81e1ae6c18452f5d20fb09d563
DiseaseAcute monocytic leukemia

BLM FANCD2 CTC1

2.68e-0526663C0023465
DiseaseMiller Dieker syndrome

BLM FANCD2 CTC1

3.75e-0529663C0265219
Diseasearrhythmogenic right ventricular cardiomyopathy (is_implicated_in)

DSP RYR2

2.19e-0410662DOID:0050431 (is_implicated_in)
Diseaseleukemia

BLM FANCD2 SETD2

2.58e-0455663C0023418
DiseaseHypertrophic Cardiomyopathy

DSP OBSCN RYR2

2.87e-0457663C0007194
DiseaseMYELODYSPLASTIC SYNDROME

BLM FANCD2 CTC1

4.62e-0467663C3463824
DiseaseLeukemia, Myelocytic, Acute

BLM FANCD2 SETD2 CTC1

6.20e-04173664C0023467
Diseasemyeloperoxidase (MPO)-DNA complex measurement

KIF26B EPX

1.11e-0322662EFO_0011039
DiseaseBrain Diseases

CTC1 LAMC3

1.43e-0325662C0006111
DiseaseEncephalopathies

CTC1 LAMC3

1.67e-0327662C0085584
Diseaseintellectual disability (is_implicated_in)

CDK13 ARHGEF6

2.06e-0330662DOID:1059 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
PKRRAACNLQRLLEN

CEP152

1411

O94986
GQCQDLRKRKQLELQ

ARHGEF6

416

Q15052
CLGSRSNKQRQQILL

ANXA11

226

P50995
LNNLNKLNSALCNRR

BIRC6

766

Q9NR09
CLLRLRNKLRGVQRN

CTC1

211

Q2NKJ3
INQKQFQRLRALLGC

ALDH3B1

286

P43353
GLQRQARQCQLQRPL

CD248

86

Q9HCU0
NRAINRCLPLNFRKD

ATAD2

381

Q6PL18
LRNIVRAQGKLCQLR

DNHD1

3816

Q96M86
RDIKCSNILLNNRGQ

CDK13

836

Q14004
SQQILRQNRGRKACD

RPS19BP1

91

Q86WX3
CSGKLQQVARRAQRA

LZTS3

371

O60299
RNQRLEKALQQLARG

LZTS1

556

Q9Y250
LCRKIIGRRNRNQEA

NLRP11

81

P59045
RRLLQNGKLFCTREN

SPINK5

636

Q9NQ38
RQKLRRQLLAQQLGA

METTL14

11

Q9HCE5
SQAQSNLLGKCRRPR

MNX1

231

P50219
NCNARLVELKRQALR

KIF26B

131

Q2KJY2
QQNKRQLERRLGDLQ

MYO18A

1401

Q92614
RCNNKRRPLLGASNQ

EPX

151

P11678
DGQNLEKRRNLLNCL

CUL7

1556

Q14999
QAKRLLGQIVDRCRN

FUBP3

136

Q96I24
ENLRRTVQPNKDNCR

RASAL2

151

Q9UJF2
LRKCQNARDNLNRIK

LRRC18

211

Q8N456
QARLRGQLKEQRVRC

GOLGA2

751

Q08379
LCRQNPTERLGNLKN

PRKG2

686

Q13237
RRRINKRGAKNCNAI

ITM2C

236

Q9NQX7
KGNIRQRQKCLESQR

GALNT14

421

Q96FL9
LIRNKARNRQNCALL

OBSCN

5846

Q5VST9
QRQLVCLARAILRKN

ABCC4

1181

O15439
RQRIAQRLKEAQNTC

DLST

231

P36957
VKAPQGRRLNRECLQ

BTBD18

131

B2RXH4
CGNELLQQRNIRRKL

BLM

396

P54132
NCLRRRDAGLLNQLQ

DACT1

116

Q9NYF0
LREKLNKLRQQNACL

CCDC18

116

Q5T9S5
RGQLEAQRLEVQQCR

CROCC2

466

H7BZ55
RRGLQQACGRLEQRQ

CROCC2

686

H7BZ55
LQGRCRKKEAARRQQ

DYTN

296

A2CJ06
ERQILLQQQKICRNR

CEP126

56

Q9P2H0
QRRRAEENALQQKAC

DSP

1266

P15924
QGQQRRVCRDLPLKN

BCE1

16

O60756
ELIRKLQQRGCRAGN

DGCR6L

181

Q9BY27
RSQGESQKQILERCR

CSAD

61

Q9Y600
RLLIRGQDQDCFQLQ

CEP192

1801

Q8TEP8
NQCISLLNRGQKERL

GOLGA8B

321

A8MQT2
LLAALIRGNRKNCAQ

RYR2

536

Q92736
LQQAGNVLRQRCELL

C19orf25

76

Q9UFG5
RVLRNKIRSGCIQEQ

FANCD2

401

Q9BXW9
LRRTRLQQQKCVNGN

MCMBP

626

Q9BTE3
EGRCDVNVRNRKLQS

MIB2

656

Q96AX9
LRKLSRQCQEQIARA

ABCB8

316

Q9NUT2
QVLINCRNNKKLLGR

SNRPD2

41

P62316
LCLQSRRQKQRQISG

SOCS5

331

O75159
LKTLLVNNNRICRIG

SNRPA1

66

P09661
LRRQCQQLESKRGRI

WHAMM

461

Q8TF30
RKRERNQQAELCKNG

PITX2

141

Q99697
RCGIRNQQRLFSLKT

PRORP

36

O15091
EVKIICQRRSQLNNR

SPTBN5

2331

Q9NRC6
CRLQAQDLRQEGQQL

SPTBN5

3366

Q9NRC6
RNIQNLVQRLKRGRC

CIAO3

371

Q9H6Q4
NRGQCVKQRRQADGR

WFDC1

176

Q9HC57
AGRQRCERQREQKAN

RIBC1

226

Q8N443
QLRCRQQQLQKRIAY

MYCL

346

P12524
RENRRNNGLSGKCLQ

SETD2

946

Q9BYW2
QQALRQKTGRRLLCG

ZDHHC23

386

Q8IYP9
AKCGRNFRQRGQLLR

ZNF786

456

Q8N393
KRARQVCNLGAEQTL

SMC5

821

Q8IY18
GVGIQRRKQVCQRLA

ADAMTSL3

836

P82987
REQLQRLNKGARCAQ

LAMC3

1091

Q9Y6N6
QAQLRRLCQVAAKGI

NLRP14

421

Q86W24