Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of postsynaptic actin cytoskeleton	POTEF POTEE POTEI POTEJ	3.96e-07	11	120	4	GO:0098973
GeneOntologyMolecularFunction	calcium ion binding	FAT4 DSC3 FSTL5 IDS PKD1L3 TBC1D8B ITIH4 TBC1D9 FAT1 CELSR1 CDH20 PCDH11X DCHS1 EML1 CDH5 PCDHGA8 NOTCH3	2.46e-06	749	120	17	GO:0005509
GeneOntologyMolecularFunction	structural constituent of postsynapse	POTEF POTEE POTEI POTEJ	3.92e-05	32	120	4	GO:0099186
GeneOntologyMolecularFunction	structural constituent of synapse	POTEF POTEE POTEI POTEJ	1.16e-04	42	120	4	GO:0098918
GeneOntologyMolecularFunction	cytoskeleton-nuclear membrane anchor activity	SUN2 SYNE2	3.54e-04	5	120	2	GO:0140444
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	ARHGAP32 GAPVD1 GBF1 MYO9B RAPGEF1 TBC1D8B TBC1D9 PLEKHG1 FBXO8 VAV3	9.78e-04	507	120	10	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	ARHGAP32 GAPVD1 GBF1 MYO9B RAPGEF1 TBC1D8B TBC1D9 PLEKHG1 FBXO8 VAV3	9.78e-04	507	120	10	GO:0030695
GeneOntologyMolecularFunction	ATP-dependent peptidase activity	LONP2 LONP1	9.79e-04	8	120	2	GO:0004176
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	FAT4 DSC3 FAT1 CELSR1 CDH20 PCDH11X DCHS1 CDH5 PCDHGA8	1.61e-06	187	121	9	GO:0007156
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	FAT4 DSC3 FAT1 CELSR1 TENM4 CDH20 PCDH11X DCHS1 CDH5 PCDHGA8	1.61e-05	313	121	10	GO:0098742
GeneOntologyBiologicalProcess	postsynaptic actin cytoskeleton organization	POTEF POTEE POTEI POTEJ	3.14e-05	31	121	4	GO:0098974
GeneOntologyBiologicalProcess	nuclear migration along microfilament	SUN2 SYNE2	3.41e-05	2	121	2	GO:0031022
GeneOntologyBiologicalProcess	postsynaptic cytoskeleton organization	POTEF POTEE POTEI POTEJ	5.13e-05	35	121	4	GO:0099188
GeneOntologyBiologicalProcess	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration	SUN2 SYNE2	1.02e-04	3	121	2	GO:0021817
GeneOntologyBiologicalProcess	cell-cell adhesion	FAT4 DSC3 PDPK1 CLEC7A RAPGEF1 FAT1 CELSR1 CD5 TENM4 CDH20 EGFR PCDH11X DCHS1 LRP5 PRKCD CDH5 PCDHGA8	1.83e-04	1077	121	17	GO:0098609
GeneOntologyBiologicalProcess	condensed mesenchymal cell proliferation	FAT4 DCHS1	2.03e-04	4	121	2	GO:0072137
GeneOntologyBiologicalProcess	cell morphogenesis	KIF13B ARHGAP32 MYO9B POTEF CNMD EDNRA B4GALT5 POTEE FAT1 CDH20 NSMF EGFR SEMA5B TTL POTEI POTEJ CDH5 NOTCH3	2.06e-04	1194	121	18	GO:0000902
GeneOntologyBiologicalProcess	positive regulation of cell migration	ARHGAP32 MYLK PDPK1 CLEC7A EDNRA FAT1 NSMF EGFR SEMA5B SUN2 SYNE2 CDH5 LRRC15	2.12e-04	691	121	13	GO:0030335
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	KIF13B ARHGAP32 MYO9B POTEF EDNRA B4GALT5 POTEE NSMF EGFR SEMA5B TTL POTEI POTEJ NOTCH3	3.20e-04	819	121	14	GO:0120039
GeneOntologyBiologicalProcess	positive regulation of cell motility	ARHGAP32 MYLK PDPK1 CLEC7A EDNRA FAT1 NSMF EGFR SEMA5B SUN2 SYNE2 CDH5 LRRC15	3.37e-04	725	121	13	GO:2000147
GeneOntologyBiologicalProcess	modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration	SUN2 SYNE2	3.37e-04	5	121	2	GO:0021815
GeneOntologyBiologicalProcess	nuclear migration along microtubule	SUN2 SYNE2	3.37e-04	5	121	2	GO:0030473
GeneOntologyBiologicalProcess	cellular response to abiotic stimulus	MYLK WRN PKD1L3 EDNRA DDIAS NSMF EGFR KCNE1 PRKCD	3.44e-04	371	121	9	GO:0071214
GeneOntologyBiologicalProcess	cellular response to environmental stimulus	MYLK WRN PKD1L3 EDNRA DDIAS NSMF EGFR KCNE1 PRKCD	3.44e-04	371	121	9	GO:0104004
GeneOntologyBiologicalProcess	cell projection morphogenesis	KIF13B ARHGAP32 MYO9B POTEF EDNRA B4GALT5 POTEE NSMF EGFR SEMA5B TTL POTEI POTEJ NOTCH3	3.49e-04	826	121	14	GO:0048858
GeneOntologyBiologicalProcess	ARF protein signal transduction	GBF1 MYO9B FBXO8	3.64e-04	24	121	3	GO:0032011
GeneOntologyBiologicalProcess	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	RAPGEF1 PRKCD VAV3	4.12e-04	25	121	3	GO:0002433
GeneOntologyBiologicalProcess	Fc-gamma receptor signaling pathway involved in phagocytosis	RAPGEF1 PRKCD VAV3	4.12e-04	25	121	3	GO:0038096
GeneOntologyBiologicalProcess	positive regulation of locomotion	ARHGAP32 MYLK PDPK1 CLEC7A EDNRA FAT1 NSMF EGFR SEMA5B SUN2 SYNE2 CDH5 LRRC15	4.19e-04	742	121	13	GO:0040017
GeneOntologyCellularComponent	NuA4 histone acetyltransferase complex	POTEF POTEE POTEI POTEJ	3.39e-05	32	121	4	GO:0035267
GeneOntologyCellularComponent	H4/H2A histone acetyltransferase complex	POTEF POTEE POTEI POTEJ	3.39e-05	32	121	4	GO:0043189
GeneOntologyCellularComponent	H4 histone acetyltransferase complex	POTEF POTEE POTEI POTEJ	1.32e-04	45	121	4	GO:1902562
Domain	ANK	POTEB3 POTEF POTEG POTED ANKRD49 POTEB2 POTEC POTEE POTEM POTEI POTEJ POTEH POTEB NOTCH3	9.21e-10	251	121	14	SM00248
Domain	ANK_REPEAT	POTEB3 POTEF POTEG POTED ANKRD49 POTEB2 POTEC POTEE POTEM POTEI POTEJ POTEH POTEB NOTCH3	1.02e-09	253	121	14	PS50088
Domain	ANK_REP_REGION	POTEB3 POTEF POTEG POTED ANKRD49 POTEB2 POTEC POTEE POTEM POTEI POTEJ POTEH POTEB NOTCH3	1.07e-09	254	121	14	PS50297
Domain	Ankyrin_rpt	POTEB3 POTEF POTEG POTED ANKRD49 POTEB2 POTEC POTEE POTEM POTEI POTEJ POTEH POTEB NOTCH3	1.61e-09	262	121	14	IPR002110
Domain	Ankyrin_rpt-contain_dom	POTEB3 POTEF POTEG ANKRD49 POTEB2 POTEC POTEE POTEM POTEI POTEJ POTEH POTEB NOTCH3	1.07e-08	254	121	13	IPR020683
Domain	Ank_2	POTEB3 POTEF POTEG ANKRD49 POTEB2 POTEC POTEE POTEM POTEI POTEJ POTEH NOTCH3	1.55e-08	215	121	12	PF12796
Domain	Ank	POTEF POTEG POTED ANKRD49 POTEC POTEE POTEM POTEI POTEJ POTEH POTEB NOTCH3	2.98e-08	228	121	12	PF00023
Domain	Cadherin_CS	FAT4 DSC3 FAT1 CELSR1 CDH20 PCDH11X DCHS1 CDH5 PCDHGA8	3.69e-08	109	121	9	IPR020894
Domain	CADHERIN_1	FAT4 DSC3 FAT1 CELSR1 CDH20 PCDH11X DCHS1 CDH5 PCDHGA8	5.05e-08	113	121	9	PS00232
Domain	Cadherin	FAT4 DSC3 FAT1 CELSR1 CDH20 PCDH11X DCHS1 CDH5 PCDHGA8	5.05e-08	113	121	9	PF00028
Domain	CADHERIN_2	FAT4 DSC3 FAT1 CELSR1 CDH20 PCDH11X DCHS1 CDH5 PCDHGA8	5.45e-08	114	121	9	PS50268
Domain	-	FAT4 DSC3 FAT1 CELSR1 CDH20 PCDH11X DCHS1 CDH5 PCDHGA8	5.45e-08	114	121	9	2.60.40.60
Domain	CA	FAT4 DSC3 FAT1 CELSR1 CDH20 PCDH11X DCHS1 CDH5 PCDHGA8	5.88e-08	115	121	9	SM00112
Domain	Cadherin-like	FAT4 DSC3 FAT1 CELSR1 CDH20 PCDH11X DCHS1 CDH5 PCDHGA8	6.35e-08	116	121	9	IPR015919
Domain	Cadherin	FAT4 DSC3 FAT1 CELSR1 CDH20 PCDH11X DCHS1 CDH5 PCDHGA8	7.36e-08	118	121	9	IPR002126
Domain	-	POTEB3 POTEF POTEG ANKRD49 POTEB2 POTEC POTEE POTEM POTEI POTEJ POTEH NOTCH3	7.50e-08	248	121	12	1.25.40.20
Domain	Actin_CS	POTEF POTEE POTEI POTEJ	2.87e-06	16	121	4	IPR004001
Domain	ACTINS_2	POTEF POTEE POTEI POTEJ	3.74e-06	17	121	4	PS00432
Domain	Actin/actin-like_CS	POTEF POTEE POTEI POTEJ	4.78e-06	18	121	4	IPR020902
Domain	ACTINS_ACT_LIKE	POTEF POTEE POTEI POTEJ	6.03e-06	19	121	4	PS01132
Domain	Pept_S16_C	LONP2 LONP1	4.16e-05	2	121	2	IPR008269
Domain	Peptidase_S16_AS	LONP2 LONP1	4.16e-05	2	121	2	IPR008268
Domain	Lon_bac/euk-typ	LONP2 LONP1	4.16e-05	2	121	2	IPR004815
Domain	Lon_Prtase	LONP2 LONP1	4.16e-05	2	121	2	IPR027065
Domain	LON_PROTEOLYTIC	LONP2 LONP1	4.16e-05	2	121	2	PS51786
Domain	Lon_C	LONP2 LONP1	4.16e-05	2	121	2	PF05362
Domain	LON_SER	LONP2 LONP1	4.16e-05	2	121	2	PS01046
Domain	Actin	POTEF POTEE POTEI POTEJ	4.61e-05	31	121	4	IPR004000
Domain	Actin	POTEF POTEE POTEI POTEJ	4.61e-05	31	121	4	PF00022
Domain	ACTIN	POTEF POTEE POTEI POTEJ	4.61e-05	31	121	4	SM00268
Domain	Cadherin_C	DSC3 CDH20 CDH5	5.50e-04	25	121	3	PF01049
Domain	Cadherin_cytoplasmic-dom	DSC3 CDH20 CDH5	5.50e-04	25	121	3	IPR000233
Domain	LON_substr_bdg	LONP2 LONP1	6.14e-04	6	121	2	PF02190
Domain	LON	LONP2 LONP1	6.14e-04	6	121	2	SM00464
Domain	LON_N	LONP2 LONP1	6.14e-04	6	121	2	PS51787
Domain	LON_substr-bd_dom	LONP2 LONP1	6.14e-04	6	121	2	IPR003111
Domain	EGF	FAT4 FAT1 CELSR1 TENM4 MUC17 LRP5 NOTCH3	8.56e-04	235	121	7	SM00181
Domain	EGF_3	FAT4 FAT1 CELSR1 TENM4 MUC17 LRP5 NOTCH3	8.56e-04	235	121	7	PS50026
Domain	Catenin_binding_dom	DSC3 CDH20 CDH5	8.57e-04	29	121	3	IPR027397
Domain	-	DSC3 CDH20 CDH5	8.57e-04	29	121	3	4.10.900.10
Domain	EGF-like_dom	FAT4 FAT1 CELSR1 TENM4 MUC17 LRP5 NOTCH3	1.20e-03	249	121	7	IPR000742
Domain	EGF-like_Ca-bd_dom	FAT4 FAT1 CELSR1 LRP5 NOTCH3	1.28e-03	124	121	5	IPR001881
Domain	EGF_1	FAT4 FAT1 CELSR1 TENM4 MUC17 LRP5 NOTCH3	1.37e-03	255	121	7	PS00022
Domain	BRICHOS	CNMD ITM2B	1.45e-03	9	121	2	SM01039
Domain	BRICHOS_dom	CNMD ITM2B	1.45e-03	9	121	2	IPR007084
Domain	BRICHOS	CNMD ITM2B	1.45e-03	9	121	2	PF04089
Domain	BRICHOS	CNMD ITM2B	1.45e-03	9	121	2	PS50869
Domain	EGF-like_CS	FAT4 FAT1 CELSR1 TENM4 MUC17 LRP5 NOTCH3	1.57e-03	261	121	7	IPR013032
Domain	EGF_2	FAT4 FAT1 CELSR1 TENM4 MUC17 LRP5 NOTCH3	1.71e-03	265	121	7	PS01186
Domain	VIT	VWA5B2 ITIH4	1.81e-03	10	121	2	PS51468
Domain	VIT	VWA5B2 ITIH4	1.81e-03	10	121	2	IPR013694
Domain	LAM_G_DOMAIN	FAT4 FAT1 CELSR1	1.90e-03	38	121	3	PS50025
Domain	Laminin_G_2	FAT4 FAT1 CELSR1	2.20e-03	40	121	3	PF02210
Domain	LamG	FAT4 FAT1 CELSR1	2.89e-03	44	121	3	SM00282
Domain	TTL	TTL TTLL1	3.10e-03	13	121	2	PS51221
Domain	TTL/TTLL_fam	TTL TTLL1	3.10e-03	13	121	2	IPR004344
Domain	TTL	TTL TTLL1	3.10e-03	13	121	2	PF03133
Domain	Growth_fac_rcpt_	FAT4 FAT1 CELSR1 EGFR NOTCH3	3.48e-03	156	121	5	IPR009030
Domain	EGF_CA	FAT4 FAT1 LRP5 NOTCH3	3.93e-03	99	121	4	PS01187
Domain	ASX_HYDROXYL	FAT4 FAT1 CELSR1 NOTCH3	4.07e-03	100	121	4	PS00010
Domain	-	GBF1 FBXO8	4.14e-03	15	121	2	1.10.1000.11
Domain	Sec7	GBF1 FBXO8	4.14e-03	15	121	2	PF01369
Domain	cAMP_dep_PK_reg_su_I/II_a/b	TEX55 SPA17	4.14e-03	15	121	2	IPR003117
Domain	Sec7_alpha_orthog	GBF1 FBXO8	4.14e-03	15	121	2	IPR023394
Domain	GRAM	TBC1D8B TBC1D9	4.71e-03	16	121	2	SM00568
Domain	SEC7	GBF1 FBXO8	4.71e-03	16	121	2	PS50190
Domain	Sec7	GBF1 FBXO8	4.71e-03	16	121	2	SM00222
Domain	Sec7_dom	GBF1 FBXO8	4.71e-03	16	121	2	IPR000904
Domain	EGF-type_Asp/Asn_hydroxyl_site	FAT4 FAT1 CELSR1 NOTCH3	5.01e-03	106	121	4	IPR000152
Domain	-	DMXL2 RBBP4 FSTL5 SEMA5B KCTD3 EML1 DYNC1I2	6.01e-03	333	121	7	2.130.10.10
Domain	C1_1	MYO9B PRKCD VAV3	6.02e-03	57	121	3	PF00130
Domain	WD40/YVTN_repeat-like_dom	DMXL2 RBBP4 FSTL5 SEMA5B KCTD3 EML1 DYNC1I2	6.20e-03	335	121	7	IPR015943
Domain	Laminin_G	FAT4 FAT1 CELSR1	6.32e-03	58	121	3	IPR001791
Pubmed	POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.	POTEB3 POTED POTEB2 POTEC POTEJ POTEH POTEB	4.64e-17	8	123	7	12475935
Pubmed	Two novel transcripts encoding two Ankyrin repeat containing proteins have preponderant expression during the mouse spermatogenesis.	POTEG POTEB2 POTEC POTEM POTEH POTEB	1.73e-15	6	123	6	17171436
Pubmed	Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths.	POTEB3 POTEG POTED POTEE POTEH POTEB	1.21e-14	7	123	6	15276201
Pubmed	The Vertebrate Genome Annotation browser 10 years on.	POTEB3 POTEF POTEG POTEB2 POTEC POTEE POTEM MUC17 POTEI POTEJ POTEH POTEB	6.84e-13	163	123	12	24316575
Pubmed	Identification of a novel actin isoform in hepatocellular carcinoma.	POTEF POTEG POTEE POTEM POTEI POTEJ	8.43e-12	15	123	6	16824795
Pubmed	Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.	POTED POTEE POTEM POTEI POTEJ	6.35e-11	9	123	5	16364570
Pubmed	Identification and characterization of TSAP, a novel gene specifically expressed in testis during spermatogenesis.	POTEC POTEM POTEH POTEB	1.49e-10	4	123	4	17342726
Pubmed	Dachsous1-Fat4 Signaling Controls Endothelial Cell Polarization During Lymphatic Valve Morphogenesis-Brief Report.	FAT4 CELSR1 DCHS1 CDH5	1.85e-08	9	123	4	28705793
Pubmed	Evolution and expression of chimeric POTE-actin genes in the human genome.	POTEF POTEE POTEJ	4.32e-08	3	123	3	17101985
Pubmed	Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.	FAT4 DSC3 CELSR1 DCHS1 NUP93 ITM2B	1.45e-07	67	123	6	21875946
Pubmed	Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.	DMXL2 POTEF POTEE POTEI POTEJ USPL1 STAG3	1.08e-06	149	123	7	22664934
Pubmed	Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.	FAT4 FAT1 DCHS1	1.50e-06	7	123	3	16059920
Pubmed	Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation.	FAT4 FAT1 DCHS1	6.98e-06	11	123	3	26114487
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	KIF13B RBBP4 MYO9B RADX ANKRD49 SGO1 POTEE ARNT POTEI POTEJ YTHDF3	8.21e-06	588	123	11	38580884
Pubmed	LE-PAS, a novel Arnt-dependent HLH-PAS protein, is expressed in limbic tissues and transactivates the CNS midline enhancer element.	ARNT NPAS4	1.24e-05	2	123	2	15363889
Pubmed	A primate-specific POTE-actin fusion protein plays a role in apoptosis.	POTEF POTEE	1.24e-05	2	123	2	19669888
Pubmed	Epidermal Growth Factor Receptor Mutation Enhances Expression of Cadherin-5 in Lung Cancer Cells.	EGFR CDH5	1.24e-05	2	123	2	27362942
Pubmed	Isolation and characterization of two growth factor-stimulated protein kinases that phosphorylate the epidermal growth factor receptor at threonine 669.	EGFR ELF3	1.24e-05	2	123	2	1651322
Pubmed	Coiled-Coil Domains of SUN Proteins as Intrinsic Dynamic Regulators.	SUN2 SYNE2	1.24e-05	2	123	2	26688217
Pubmed	Aberrant expression of epidermal growth factor receptor and its interaction with protein kinase C δ in inflammation associated neoplastic transformation of human esophageal epithelium in high risk populations.	EGFR PRKCD	1.24e-05	2	123	2	21155880
Pubmed	Giant cadherins Fat and Dachsous self-bend to organize properly spaced intercellular junctions.	FAT4 DCHS1	1.24e-05	2	123	2	25355906
Pubmed	The endothelin A receptor and epidermal growth factor receptor signaling converge on β-catenin to promote ovarian cancer metastasis.	EDNRA EGFR	1.24e-05	2	123	2	22480520
Pubmed	Linear arrays of nuclear envelope proteins harness retrograde actin flow for nuclear movement.	SUN2 SYNE2	1.24e-05	2	123	2	20724637
Pubmed	Combined targeting of endothelin A receptor and epidermal growth factor receptor in ovarian cancer shows enhanced antitumor activity.	EDNRA EGFR	1.24e-05	2	123	2	17616694
Pubmed	Selective POTE paralogs on chromosome 2 are expressed in human embryonic stem cells.	POTEE POTEJ	1.24e-05	2	123	2	18447647
Pubmed	Multiorgan failure with abnormal receptor metabolism in mice mimicking Samd9/9L syndromes.	SAMD9L EGFR	1.24e-05	2	123	2	33373325
Pubmed	Structure of the planar cell polarity cadherins Fat4 and Dachsous1.	FAT4 DCHS1	1.24e-05	2	123	2	36797229
Pubmed	Mammalian cadherins DCHS1-FAT4 affect functional cerebral architecture.	FAT4 DCHS1	1.24e-05	2	123	2	25930014
Pubmed	Desmocollin 3 mediates follicle stimulating hormone-induced ovarian epithelial cancer cell proliferation by activating the EGFR/Akt signaling pathway.	DSC3 EGFR	1.24e-05	2	123	2	26261554
Pubmed	NOTCH3 is a prognostic factor that promotes glioma cell proliferation, migration and invasion via activation of CCND1 and EGFR.	EGFR NOTCH3	3.71e-05	3	123	2	24143218
Pubmed	CD5 dynamically calibrates basal NF-κB signaling in T cells during thymic development and peripheral activation.	THEMIS CD5	3.71e-05	3	123	2	32513716
Pubmed	EGFR and SYNE2 are associated with p21 expression and SYNE2 variants predict post-operative clinical outcomes in HBV-related hepatocellular carcinoma.	EGFR SYNE2	3.71e-05	3	123	2	27502069
Pubmed	EGF receptor and PKCδ kinase activate DNA damage-induced pro-survival and pro-apoptotic signaling via biphasic activation of ERK and MSK1 kinases.	EGFR PRKCD	3.71e-05	3	123	2	30679314
Pubmed	Rab18 regulates lipolysis via Arf/GBF1 and adipose triglyceride lipase.	PNPLA2 GBF1	3.71e-05	3	123	2	31610914
Pubmed	Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim.	EGFR NOTCH3	3.71e-05	3	123	2	19881544
Pubmed	Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins.	SUN2 SYNE2	3.71e-05	3	123	2	19843581
Pubmed	Structures of NPAS4-ARNT and NPAS4-ARNT2 heterodimers reveal new dimerization modalities in the bHLH-PAS transcription factor family.	ARNT NPAS4	3.71e-05	3	123	2	36343253
Pubmed	Platelet-derived growth factor mimics phorbol diester action on epidermal growth factor receptor phosphorylation at threonine-654.	EGFR PRKCD	3.71e-05	3	123	2	2987962
Pubmed	Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells.	EGFR PRKCD	3.71e-05	3	123	2	15618223
Pubmed	Phosphorylation of PKCδ by FER tips the balance from EGFR degradation to recycling.	EGFR PRKCD	3.71e-05	3	123	2	33411917
Pubmed	Potassium channels involved in human sperm volume regulation--quantitative studies at the protein and mRNA levels.	KCNE1 KCNK5	3.71e-05	3	123	2	18157847
Pubmed	PKCδ localization at the membrane increases matrix traction force dependent on PLCγ1/EGFR signaling.	EGFR PRKCD	3.71e-05	3	123	2	24155954
Pubmed	ELF3 Is a Target That Promotes Therapeutic Efficiency in EGFR Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer Cells via Inhibiting PKCί.	EGFR ELF3	3.71e-05	3	123	2	34830169
Pubmed	Tumor-promoting phorbol diesters cause the phosphorylation of epidermal growth factor receptors in normal human fibroblasts at threonine-654.	EGFR PRKCD	3.71e-05	3	123	2	2984676
Pubmed	m6 A reader YTHDF3 triggers the progression of hepatocellular carcinoma through the YTHDF3/m6 A-EGFR/STAT3 axis and EMT.	EGFR YTHDF3	3.71e-05	3	123	2	37449789
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	PNPLA2 GBF1 RADX ANKRD49 USP19 EGFR SYNE2 EML1	4.73e-05	363	123	8	25036637
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SECISBP2L KIF13B ARHGAP32 DMXL2 GBF1 ESCO1 TBC1D9 SAMD9L SUN2	6.78e-05	493	123	9	15368895
Pubmed	The TIP60 Complex Is a Conserved Coactivator of HIF1A.	GBF1 MYO9B FAT1 ARNT NUP93	7.02e-05	120	123	5	27320910
Pubmed	Shugoshin protects centromere pairing and promotes segregation of nonexchange partner chromosomes in meiosis.	SGO1 HFM1	7.41e-05	4	123	2	31019073
Pubmed	Protein Kinase Cι Drives a NOTCH3-dependent Stem-like Phenotype in Mutant KRAS Lung Adenocarcinoma.	ELF3 NOTCH3	7.41e-05	4	123	2	26977885
Pubmed	Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1.	PDPK1 PRKCD	7.41e-05	4	123	2	9748166
Pubmed	LINC complex alterations in DMD and EDMD/CMT fibroblasts.	SUN2 SYNE2	7.41e-05	4	123	2	22555292
Pubmed	Coupling of the nucleus and cytoplasm: role of the LINC complex.	SUN2 SYNE2	7.41e-05	4	123	2	16380439
Pubmed	Phosphorylation sites of protein kinase C delta in H2O2-treated cells and its activation by tyrosine kinase in vitro.	PDPK1 PRKCD	7.41e-05	4	123	2	11381116
Pubmed	Regulation of both PDK1 and the phosphorylation of PKC-zeta and -delta by a C-terminal PRK2 fragment.	PDPK1 PRKCD	7.41e-05	4	123	2	11781095
Pubmed	Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.	SUN2 SYNE2	7.41e-05	4	123	2	20108321
Pubmed	The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal.	SUN2 SYNE2	7.41e-05	4	123	2	33686165
Pubmed	Cell-Free RNA Content in Peripheral Blood as Potential Biomarkers for Detecting Circulating Tumor Cells in Non-Small Cell Lung Carcinoma.	EGFR ELF3	7.41e-05	4	123	2	27827952
Pubmed	GAPex-5 mediates ubiquitination, trafficking, and degradation of epidermal growth factor receptor.	GAPVD1 EGFR	7.41e-05	4	123	2	17545148
Pubmed	The β-glucan receptor Dectin-1 activates the integrin Mac-1 in neutrophils via Vav protein signaling to promote Candida albicans clearance.	CLEC7A VAV3	7.41e-05	4	123	2	22177564
Pubmed	Depletion of WRN protein causes RACK1 to activate several protein kinase C isoforms.	WRN PRKCD	7.41e-05	4	123	2	19966859
Pubmed	Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool.	FAT4 FAT1 DCHS1	8.27e-05	24	123	3	26116661
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	DMXL2 PDPK1 RAPGEF1 CD5 EGFR	1.14e-04	133	123	5	15144186
Pubmed	Characterization of PDK2 activity against protein kinase B gamma.	PDPK1 PRKCD	1.23e-04	5	123	2	12162751
Pubmed	Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.	SUN2 SYNE2	1.23e-04	5	123	2	19933576
Pubmed	Interaction between the triglyceride lipase ATGL and the Arf1 activator GBF1.	PNPLA2 GBF1	1.23e-04	5	123	2	21789191
Pubmed	LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.	SUN2 SYNE2	1.23e-04	5	123	2	22632968
Pubmed	Personalized copy number and segmental duplication maps using next-generation sequencing.	POTEB3 POTEB	1.23e-04	5	123	2	19718026
Pubmed	Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly.	FAT4 FAT1	1.23e-04	5	123	2	30862798
Pubmed	Multiple cadherins are expressed in human fibroblasts.	FAT1 DCHS1	1.23e-04	5	123	2	9199196
Pubmed	PKCdelta survival signaling in cells containing an activated p21Ras protein requires PDK1.	PDPK1 PRKCD	1.23e-04	5	123	2	19146951
Pubmed	Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development.	FAT4 DCHS1	1.23e-04	5	123	2	24056717
Pubmed	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.	SUN2 SYNE2	1.23e-04	5	123	2	18396275
Pubmed	Regulation of lysophosphatidic acid-induced epidermal growth factor receptor transactivation and interleukin-8 secretion in human bronchial epithelial cells by protein kinase Cdelta, Lyn kinase, and matrix metalloproteinases.	EGFR PRKCD	1.23e-04	5	123	2	16687414
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 PNPLA2 GBF1 MYO9B RAPGEF1 REV3L TBC1D9 PLEKHG1 FAT1 CELSR1 KCNK5 LRP5 PCNX1	1.53e-04	1105	123	13	35748872
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	PCSK2 DSC3 NAALADL2 PKHD1L1 EDNRA PLEKHG1 DDIAS TENM4 CDH20 KCNK5 FYB2	1.54e-04	814	123	11	23251661
Pubmed	The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer.	SECISBP2L RAPGEF1 SYNE2	1.63e-04	30	123	3	30480076
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KIF13B MYLK POTEF SKIDA1 SGO1 TASOR2 POTEE SYNE2 TTLL1 CEP295 POTEI POTEJ USPL1 PCDHGA8 DYNC1I2	1.80e-04	1442	123	15	35575683
Pubmed	PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells.	PDPK1 ARNT	1.84e-04	6	123	2	23183047
Pubmed	Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity.	PRKCD VAV3	1.84e-04	6	123	2	27926862
Pubmed	Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.	SUN2 SYNE2	1.84e-04	6	123	2	33058875
Pubmed	Vav family proteins couple to diverse cell surface receptors.	EGFR VAV3	1.84e-04	6	123	2	10938113
Pubmed	Samp1 is a component of TAN lines and is required for nuclear movement.	SUN2 SYNE2	1.84e-04	6	123	2	22349700
Pubmed	Mammalian Fat and Dachsous cadherins regulate apical membrane organization in the embryonic cerebral cortex.	FAT4 DCHS1	1.84e-04	6	123	2	19506035
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	KIF13B RELCH ARHGAP32 DSC3 RAPGEF1 SLC7A2 FAT1 EGFR PCDH11X	1.99e-04	569	123	9	30639242
Pubmed	Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression.	ARNT NPAS4	2.58e-04	7	123	2	14701734
Pubmed	Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity.	FAT4 FAT1	2.58e-04	7	123	2	22510986
Pubmed	MAGED1 is a novel regulator of a select subset of bHLH PAS transcription factors.	ARNT NPAS4	2.58e-04	7	123	2	27472814
Pubmed	GEP100 links epidermal growth factor receptor signalling to Arf6 activation to induce breast cancer invasion.	GBF1 EGFR	2.58e-04	7	123	2	18084281
Pubmed	NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.	ARNT NPAS4	2.58e-04	7	123	2	27782878
Pubmed	Dchs1-Fat4 regulation of polarized cell behaviours during skeletal morphogenesis.	FAT4 DCHS1	2.58e-04	7	123	2	27145737
Pubmed	Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells.	GAPVD1 EGFR	3.43e-04	8	123	2	19725050
Pubmed	Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow.	FAT4 CDH5	3.43e-04	8	123	2	32182215
Pubmed	Catenin α 1 mutations cause familial exudative vitreoretinopathy by overactivating Norrin/β-catenin signaling.	LRP5 CDH5	3.43e-04	8	123	2	33497368
Pubmed	Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.	POTEF POTEE POTEI POTEJ	3.85e-04	96	123	4	23580065
Pubmed	Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.	RBBP4 MYO9B LONP1 EGFR NUP93	4.08e-04	175	123	5	37866880
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	POTEF WRN TASOR2 POTEE POTEI POTEJ	4.20e-04	271	123	6	32433965
Pubmed	ERBB3-dependent AKT and ERK pathways are essential for atrioventricular cushion development in mouse embryos.	EGFR CDH5	4.39e-04	9	123	2	34714866
Pubmed	MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment.	EGFR MAP3K2	4.39e-04	9	123	2	19289468
Pubmed	Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation.	EGFR VAV3	4.39e-04	9	123	2	11094073
Interaction	POTEG interactions	POTEF POTEG POTEC EGFR POTEH	5.73e-09	12	122	5	int:POTEG
Interaction	POTEC interactions	POTEB3 POTEF POTEG POTED POTEC	9.27e-09	13	122	5	int:POTEC
Interaction	POTED interactions	POTEB3 POTED POTEC	8.62e-07	4	122	3	int:POTED
Interaction	NXPH2 interactions	FAT4 B4GALT5 FAT1 CELSR1 LRP5	1.55e-06	33	122	5	int:NXPH2
Interaction	POTEB3 interactions	POTEB3 POTEF POTED POTEB2 POTEC	2.10e-06	35	122	5	int:POTEB3
Interaction	DCANP1 interactions	FAT4 FAT1 CELSR1 DCHS1	4.62e-06	19	122	4	int:DCANP1
Interaction	LOC254896 interactions	FAT4 POTEF FAT1 CELSR1 DCHS1	6.00e-06	43	122	5	int:LOC254896
Interaction	PFDN2 interactions	ARHGAP32 POTEF SGO1 POTEE LONP1 EGFR POTEI POTEJ DYNC1I2	1.98e-05	247	122	9	int:PFDN2
Interaction	IFNE interactions	FAT4 B4GALT5 POTEE FAT1	2.01e-05	27	122	4	int:IFNE
Interaction	POTEH interactions	POTEG POTEH	3.63e-05	2	122	2	int:POTEH
Interaction	POTEB interactions	EGFR POTEB	3.63e-05	2	122	2	int:POTEB
Interaction	RYK interactions	FAT4 DSC3 CELSR1 DCHS1 NUP93 ITM2B CDH5 LRRC15	4.53e-05	212	122	8	int:RYK
Interaction	VOPP1 interactions	GBF1 EGFR LRRC15	5.92e-05	13	122	3	int:VOPP1
Interaction	PCNX1 interactions	POTEF EGFR PCNX1	5.92e-05	13	122	3	int:PCNX1
Interaction	POTEF interactions	POTEB3 THEMIS POTEF POTEG POTEC SUN2 AKR1B10 PCNX1	7.56e-05	228	122	8	int:POTEF
Interaction	PRSS37 interactions	FAT4 FAT1 LRP5	9.34e-05	15	122	3	int:PRSS37
Interaction	XAGE1A interactions	FAT4 FAT1 CELSR1 DCHS1	1.09e-04	41	122	4	int:XAGE1A
Interaction	CFI interactions	ITIH4 POTEI DYNC1I2	1.14e-04	16	122	3	int:CFI
Cytoband	2q21.1	POTEF POTEE POTEI POTEJ	1.86e-05	58	123	4	2q21.1
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEF POTEG POTED POTEB2 POTEC POTEE POTEM POTEI POTEJ POTEH POTEB	1.47e-24	13	88	11	685
GeneFamily	Ankyrin repeat domain containing	POTEF POTEG POTED ANKRD49 POTEB2 POTEC POTEE POTEM POTEI POTEJ POTEH POTEB NOTCH3	1.58e-10	242	88	13	403
GeneFamily	Cadherin related	FAT4 FAT1 DCHS1	7.21e-05	17	88	3	24
GeneFamily	BRICHOS domain containing	CNMD ITM2B	8.25e-04	9	88	2	457
GeneFamily	CD molecules\|Type II classical cadherins	CDH20 CDH5	1.76e-03	13	88	2	1186
GeneFamily	WD repeat domain containing\|GRAM domain containing\|BEACH domain containing	TBC1D8B TBC1D9	1.76e-03	13	88	2	1146
GeneFamily	Tubulin tyrosine ligase family	TTL TTLL1	2.05e-03	14	88	2	779
Coexpression	RAO_BOUND_BY_SALL4_ISOFORM_B	POTEB3 POTEF POTEG POTEB2 POTEC TBC1D9 POTEE POTEM VAV3 POTEI POTEJ POTEH POTEB	3.49e-06	584	122	13	MM1080
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_1000	CACNA1D FAT4 REV3L B4GALT5 MEX3C SLC7A2 ZFHX4 PCDH11X PRKCD TTLL1	6.61e-06	301	117	10	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000	CACNA1D FAT4 REV3L EDNRA B4GALT5 MEX3C SLC7A2 TENM4 ZFHX4 EGFR AKR1B10 SYNE2 PCDH11X PRKCD TTLL1	2.65e-05	783	117	15	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
ToppCell	RA-08._Macrophage\|World / Chamber and Cluster_Paper	DMXL2 MYO9B CLEC7A RAPGEF1 C1orf162 KCNE1 PCNX1 VAV3	6.29e-08	193	122	8	5fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-9\|TCGA-Breast / Sample_Type by Project: Shred V9	POTEF POTEE POTEM POTEI POTEJ POTEH	1.82e-07	90	122	6	96e836c7a1df279ac812b7c3aa75e6b81b614244
ToppCell	TCGA-Brain-Primary_Tumor-Glioblastoma-Primary_GBM-11\|TCGA-Brain / Sample_Type by Project: Shred V9	POTEF POTEG POTEE POTEI POTEJ	8.37e-07	63	122	5	d7dc1356a60cb527fe668328d5375f352239d911
ToppCell	COVID-19-Heart-EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	MYLK RAPGEF1 EDNRA PLEKHG1 SYNE2 CDH5 NOTCH3	9.53e-07	190	122	7	a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	RAPGEF1 PKHD1L1 B4GALT5 PLEKHG1 SYNE2 PCDH11X VAV3	1.06e-06	193	122	7	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	RA-08._Macrophage\|RA / Chamber and Cluster_Paper	DMXL2 CLEC7A RAPGEF1 C1orf162 KCNE1 PCNX1 VAV3	1.10e-06	194	122	7	ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCell	Fetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DMXL2 MYO9B CLEC7A RAPGEF1 C1orf162 KCNE1 VAV3	1.30e-06	199	122	7	22001aa733273e784051b7f750e07d99aaf7a225
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ARHGAP32 DSC3 SLC7A2 CELSR1 EGFR SYNE2 ELF3	1.34e-06	200	122	7	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	FAT4 MYLK ADAMTSL3 SLC7A2 FAT1 ZFHX4 PCDH11X	1.34e-06	200	122	7	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	Bronchial-NucSeq-Immune_Myeloid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DMXL2 MYO9B CLEC7A RAPGEF1 C1orf162 KCNE1 VAV3	1.34e-06	200	122	7	2f5b71e55c2de0e77fdae6667eb57f333acc6cd1
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FAT4 TBC1D8B FAT1 CDH20 ITM2B CPNE7	3.94e-06	152	122	6	8ff5a178a8f3550d89a003c0858820aab3773386
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FSTL5 CDH20 EGFR SEMA5B CACNG4 CPNE7	8.01e-06	172	122	6	7e1a7700a4c2b1d100da1d6e475e73498ebb605a
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Thalamus / BrainAtlas - Mouse McCarroll V32	ARHGAP32 PLEKHG1 NSMF PRKCD CPNE7	8.27e-06	100	122	5	20675fc2ffc5ab63047d38da083b50d470f3db19
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6\|Thalamus / BrainAtlas - Mouse McCarroll V32	ARHGAP32 PLEKHG1 NSMF PRKCD CPNE7	8.27e-06	100	122	5	1de3895e16f14ff32b901b18ce14d965afaa7e76
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora\|Thalamus / BrainAtlas - Mouse McCarroll V32	ARHGAP32 PLEKHG1 NSMF PRKCD CPNE7	8.27e-06	100	122	5	ff1bdb511700a041a90034d1d30dfc25f51d6c82
ToppCell	5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWA5B2 PCSK2 DSC3 POTEE POTEI POTEJ	8.84e-06	175	122	6	182e45f5c02214d6b9f317ff5dc43af8b42de978
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSC3 EDNRA CDH20 SEMA5B STAG3 NOTCH3	9.13e-06	176	122	6	8b5c2fb7e5e551df658b1d5fc7f607a27bab00d5
ToppCell	B_cells-Naive_B_cells_\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	ARHGAP32 MYLK RGS19 C1orf162 PLEKHG1 VAV3	9.74e-06	178	122	6	71ac2eca5cf13a91f86b80690748b0788392dcfc
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	VWA5B2 PCSK2 CNMD POTEI POTEJ NPAS4	1.01e-05	179	122	6	06f92c884189197c86793191c05f65e34925c097
ToppCell	IPF-Epithelial-Mesothelial\|IPF / Disease state, Lineage and Cell class	DSC3 PKHD1L1 SLC7A2 FAT1 ZFHX4 EGFR	1.04e-05	180	122	6	1fa54bf4dba72866b2295639d991af639341bc08
ToppCell	Control-Endothelial_cells-Capillary_endothelial_cells\|Control / group, cell type (main and fine annotations)	PLEKHG1 KCTD3 PCDH11X VAV3 EML1 CDH5	1.04e-05	180	122	6	b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MYLK POTEF POTEG POTEE POTEI ITM2B	1.04e-05	180	122	6	fb3d549c2a69b2157a486786ddd775ca16699ed0
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic-platelet\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MYLK POTEF POTEG POTEE POTEI ITM2B	1.04e-05	180	122	6	beb4d777e0c5fa0a59672dbc3dbb7732498605ff
ToppCell	facs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYLK ITIH4 EDNRA FAT1 SEMA5B NOTCH3	1.07e-05	181	122	6	429df38438d5a7ff490c9ede34b69e2970c7ded2
ToppCell	facs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYLK ITIH4 EDNRA FAT1 SEMA5B NOTCH3	1.07e-05	181	122	6	395cf5aa2d89b05328ab516b8c89401020b6d830
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	VWA5B2 PCSK2 FSTL5 CACNG4 POTEI POTEJ	1.14e-05	183	122	6	8820cfed27b292bc0bc9cde4005219ed41900552
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Sc17a7.Fermt1_(Subiculum/Parasubiculum)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ACP7 THEMIS DSC3 FYB2	1.17e-05	51	122	4	f71a194642de9ce603390c5063ea62d755efd1a8
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Excitatory_Neuron.Sc17a7.Fermt1_(Subiculum/Parasubiculum)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ACP7 THEMIS DSC3 FYB2	1.17e-05	51	122	4	be47f4d9c720b8e3a5698227a2dc7629e1dc61b7
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 PKHD1L1 FAT1 TENM4 ZFHX4 PCDH11X	1.18e-05	184	122	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 PKHD1L1 FAT1 TENM4 ZFHX4 PCDH11X	1.18e-05	184	122	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 PKHD1L1 FAT1 TENM4 ZFHX4 PCDH11X	1.18e-05	184	122	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP32 MYLK ADAMTSL3 EDNRA FAT1 NOTCH3	1.18e-05	184	122	6	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	PCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	VWA5B2 PCSK2 FSTL5 CACNG4 POTEI POTEJ	1.29e-05	187	122	6	98477ba04a42a8da80a72f41a182429f46283595
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 ADAMTSL3 SLC7A2 FAT1 EGFR CPNE7	1.33e-05	188	122	6	433a25fe52914e07e7ba695881f9bcca2d9467ff
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DMXL2 RADX CLEC7A TBC1D9 PLEKHG1 SLC7A2	1.37e-05	189	122	6	98f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DMXL2 RADX CLEC7A TBC1D9 PLEKHG1 SLC7A2	1.37e-05	189	122	6	f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PKHD1L1 PLEKHG1 CDH20 SEMA5B EML1 CDH5	1.41e-05	190	122	6	656483751e4bf137e4e4bfb2a03a478a8f7fcb63
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 ADAMTSL3 SLC7A2 FAT1 EGFR CPNE7	1.41e-05	190	122	6	3b8d1e66ae68c1eee64095e75195d76d97e24026
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 ADAMTSL3 SLC7A2 FAT1 EGFR CPNE7	1.41e-05	190	122	6	56cc761e50fddfb5366391518b4d8e16589b6b42
ToppCell	droplet-Kidney-nan-21m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYLK ITIH4 EDNRA SLC7A2 NPAS4 NOTCH3	1.41e-05	190	122	6	e04f47705851563515b6a66a2634cf7a574f7bda
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 ADAMTSL3 SLC7A2 FAT1 EGFR CPNE7	1.41e-05	190	122	6	25d4b591f75c26e404a34c42f1742d580af6598d
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 ADAMTSL3 SLC7A2 FAT1 EGFR CPNE7	1.41e-05	190	122	6	dc655e4782aab274f0c9b6e36a5ce315e3a1a4b9
ToppCell	RA-09._Endothelium_I\|World / Chamber and Cluster_Paper	RAPGEF1 PKHD1L1 PLEKHG1 SYNE2 EML1 CDH5	1.45e-05	191	122	6	c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYLK EDNRA FAT1 TENM4 ZFHX4 LRRC15	1.50e-05	192	122	6	67e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FAT4 CNMD ADAMTSL3 PLEKHG1 TENM4 ZFHX4	1.50e-05	192	122	6	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	RA-09._Endothelium_I\|RA / Chamber and Cluster_Paper	RAPGEF1 PKHD1L1 PLEKHG1 SYNE2 EML1 CDH5	1.50e-05	192	122	6	8a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	SECISBP2L MYO9B TBC1D9 PLEKHG1 PRKCD VAV3	1.54e-05	193	122	6	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	RAPGEF1 PKHD1L1 B4GALT5 PLEKHG1 PCDH11X VAV3	1.54e-05	193	122	6	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYLK EDNRA FAT1 TENM4 NOTCH3 LRRC15	1.54e-05	193	122	6	5de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF13B TBC1D9 SLC7A2 FAT1 ELF3 FYB2	1.59e-05	194	122	6	4579b4a44f7c731553a284843c296866027d7c0e
ToppCell	nucseq-Mesenchymal-Myocytic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYLK ADAMTSL3 EDNRA FAT1 TENM4 NOTCH3	1.59e-05	194	122	6	2d66091097e106c7bee22e5281f50724700bdf8d
ToppCell	COPD-Myeloid-Macrophage\|World / Disease state, Lineage and Cell class	KIF13B DMXL2 CLEC7A RAPGEF1 TBC1D9 PCNX1	1.59e-05	194	122	6	7d682408e9a6239a4e47befc9376e760cc3d133a
ToppCell	normal_Pleural_Fluid-T/NK_cells-CD8_low_T\|normal_Pleural_Fluid / Location, Cell class and cell subclass	THEMIS CD5 SUN2 SYNE2 ITM2B CPNE7	1.59e-05	194	122	6	11eb317f66cbced1cedadd6daba443c4d832c49f
ToppCell	droplet-Bladder-Unstain-18m-Endothelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EDNRA SLC7A2 SEMA5B CDH5 NOTCH3 CPNE7	1.63e-05	195	122	6	fbfe4a8ae9775764108b45920eec92003b24fb2e
ToppCell	COVID-19-Myeloid-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	DMXL2 MYO9B CLEC7A RAPGEF1 KCNE1 VAV3	1.63e-05	195	122	6	c172c5599379c29123340621a36bfb1fc90c2115
ToppCell	Immune-alveolar_macrophage_(MARCO_positive)\|World / Lineage, Cell type, age group and donor	DMXL2 MYO9B CLEC7A RAPGEF1 C1orf162 KCNE1	1.63e-05	195	122	6	f92114ef995e690a3bedc62c89c5fd6773d0d9f7
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|lung / Disease (COVID-19 only), tissue and cell type	DMXL2 MYO9B CLEC7A C1orf162 KCNE1 VAV3	1.63e-05	195	122	6	148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-myeloid\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PNPLA2 DMXL2 CLEC7A B4GALT5 KCNE1 PRKCD	1.63e-05	195	122	6	b0dbaae86f5703ab62f925e0f36500274044884a
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CACNA1D FAT4 MYLK EDNRA ZFHX4 EGFR	1.63e-05	195	122	6	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	droplet-Bladder-Unstain-18m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EDNRA SLC7A2 SEMA5B CDH5 NOTCH3 CPNE7	1.63e-05	195	122	6	2a6056172c41c46acfe0242be22269ef1d07921e
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	VWA5B2 PCSK2 FSTL5 CACNG4 POTEI POTEJ	1.63e-05	195	122	6	5f33ece997f074598b4201ff74f592ee07c86a06
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SECISBP2L ARHGAP32 FAT1 CELSR1 TENM4 ELF3	1.63e-05	195	122	6	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)\|Adult / Lineage, Cell type, age group and donor	DMXL2 MYO9B CLEC7A RAPGEF1 KCNE1 VAV3	1.63e-05	195	122	6	55e25f702af19146a161861cfd15f40bbda1dc35
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF13B TBC1D9 SLC7A2 FAT1 ELF3 FYB2	1.63e-05	195	122	6	3d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NAALADL2 FAT1 ZFHX4 ELF3 VAV3 FYB2	1.68e-05	196	122	6	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	COVID-19-Myeloid-Transitioning_MDM\|COVID-19 / group, cell type (main and fine annotations)	DMXL2 MYO9B CLEC7A RAPGEF1 KCNE1 VAV3	1.68e-05	196	122	6	4929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DMXL2 MYO9B CLEC7A C1orf162 KCNE1 VAV3	1.68e-05	196	122	6	7026c1fc33425e5476063d17c79e4b79356a9e01
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DMXL2 MYO9B CLEC7A C1orf162 KCNE1 VAV3	1.73e-05	197	122	6	e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCell	Control_saline-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	SECISBP2L ARHGAP32 FAT1 CELSR1 PCDH11X ELF3	1.73e-05	197	122	6	44a59dfb889577b3160a5b13ada1276771a00241
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG\|World / Primary Cells by Cluster	CNMD SGO1 CELSR1 ZFHX4 SEMA5B NOTCH3	1.73e-05	197	122	6	61749ccafeb938c310cff1de5ff924a1c794325a
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|lung / Disease (COVID-19 only), tissue and cell type	DMXL2 MYO9B CLEC7A C1orf162 KCNE1 VAV3	1.73e-05	197	122	6	a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	EDNRA SLC7A2 TENM4 ZFHX4 EGFR NOTCH3	1.73e-05	197	122	6	5afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	EDNRA SLC7A2 TENM4 ZFHX4 EGFR NOTCH3	1.73e-05	197	122	6	1baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	THEMIS DSC3 CD5 AKR1B10 SYNE2 ELF3	1.73e-05	197	122	6	80ffafa9473f4ee7a3a792d11b5541e1c984c9f0
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SECISBP2L CELSR1 EGFR SYNE2 PCDH11X ELF3	1.73e-05	197	122	6	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	Children_(3_yrs)-Immune\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DMXL2 MYO9B CLEC7A RAPGEF1 KCNE1 VAV3	1.73e-05	197	122	6	f18807124b91310fcd84238484a80ecdba684679
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|lung / Disease (COVID-19 only), tissue and cell type	DMXL2 MYO9B CLEC7A C1orf162 KCNE1 VAV3	1.73e-05	197	122	6	3896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG-25\|World / Primary Cells by Cluster	CNMD SGO1 CELSR1 ZFHX4 SEMA5B NOTCH3	1.73e-05	197	122	6	9d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	EDNRA SLC7A2 TENM4 ZFHX4 EGFR NOTCH3	1.73e-05	197	122	6	b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSC3 EDNRA TENM4 ZFHX4 SEMA5B NOTCH3	1.73e-05	197	122	6	7c275a2ac24a9a4f83fceda93a067e754837102f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	THEMIS DSC3 CD5 AKR1B10 SYNE2 ELF3	1.73e-05	197	122	6	f3dfc22ff63e6173451a0917c5aedcde793fd170
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	KIF13B CACNA1D FAT4 MYLK NAALADL2 TENM4	1.73e-05	197	122	6	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	Fetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DMXL2 CLEC7A RAPGEF1 C1orf162 KCNE1 VAV3	1.78e-05	198	122	6	ab70bf89690410221ec7aa3149bb50ac34433f99
ToppCell	COVID-19-Myeloid\|COVID-19 / group, cell type (main and fine annotations)	DMXL2 MYO9B CLEC7A RAPGEF1 KCNE1 VAV3	1.78e-05	198	122	6	33f0a919188a67d2a876b52c61a1cec2c9747969
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD4-positive_helper_T_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	THEMIS CD5 SUN2 SYNE2 PCNX1 ITM2B	1.78e-05	198	122	6	c4d8d133e571ad3a7c5de93aa7befb67cb7a003d
ToppCell	Immune\|World / Lineage, Cell type, age group and donor	DMXL2 MYO9B CLEC7A RAPGEF1 KCNE1 VAV3	1.78e-05	198	122	6	65681b54d13c6997bd90a1c2a12314a80e964fe3
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	THEMIS CD5 SUN2 SYNE2 PCNX1 ITM2B	1.78e-05	198	122	6	db107a5511571384f26e26c6301aef9a9f2423c4
ToppCell	Adult-Immune\|Adult / Lineage, Cell type, age group and donor	DMXL2 MYO9B CLEC7A RAPGEF1 KCNE1 VAV3	1.78e-05	198	122	6	9bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLEKHG1 FAT1 CELSR1 SYNE2 ELF3 NOTCH3	1.78e-05	198	122	6	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DSC3 PLEKHG1 CELSR1 TENM4 ELF3 NOTCH3	1.78e-05	198	122	6	19d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	EDNRA SLC7A2 TENM4 ZFHX4 EGFR NOTCH3	1.83e-05	199	122	6	9b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	EDNRA SLC7A2 TENM4 ZFHX4 EGFR NOTCH3	1.83e-05	199	122	6	251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MYLK ADAMTSL3 EDNRA FAT1 SEMA5B NOTCH3	1.83e-05	199	122	6	aacd3ffa40a6e6f435aa9be5b959d88812eb69d4
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	EDNRA SLC7A2 TENM4 ZFHX4 EGFR NOTCH3	1.83e-05	199	122	6	117f4f43b6c06dda553799b1063e827bce697370
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	FAT4 SGO1 FAT1 CELSR1 ZFHX4 NOTCH3	1.83e-05	199	122	6	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	MYLK ADAMTSL3 EDNRA FAT1 SYNE2 NOTCH3	1.89e-05	200	122	6	0c648941447c738caf62f2d71e296d6cca492c8b
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FAT4 FSTL5 SLC7A2 FAT1 ZFHX4 EGFR	1.89e-05	200	122	6	d0167f96314be78b6d867bbcc6e4396071d931b8
ToppCell	Parenchyma_COVID-19-Stromal-TX-Smooth_muscle-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	MYLK ADAMTSL3 EDNRA SLC7A2 SEMA5B NOTCH3	1.89e-05	200	122	6	78e9a40153d7ba5d9ea6393a37d26fc5c0220867
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYLK SAMD9L SYNE2 EML1 ITM2B CDH5	1.89e-05	200	122	6	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYLK ADAMTSL3 EDNRA FAT1 SYNE2 NOTCH3	1.89e-05	200	122	6	522a51a284d2992d519c4669e1a48c8ebcc08c80
Disease	Colorectal Carcinoma	PCSK2 RELCH FSTL5 WRN ADAMTSL3 FAT1 ARNT EGFR AKR1B10 PCDH11X DCHS1 CDH5	1.04e-05	702	108	12	C0009402
Disease	Van Maldergem Wetzburger Verloes syndrome	FAT4 DCHS1	1.33e-05	2	108	2	C1832390
Disease	Van Maldergem syndrome	FAT4 DCHS1	1.33e-05	2	108	2	cv:C1832390
Disease	Periventricular gray matter heterotopia	FAT4 DCHS1	1.33e-05	2	108	2	C1849173
Disease	Heterotopia, Periventricular, Autosomal Recessive	FAT4 DCHS1	3.97e-05	3	108	2	C1842563
Disease	nephrotic syndrome type 20 (implicated_via_orthology)	TBC1D8B TBC1D9	7.93e-05	4	108	2	DOID:0070357 (implicated_via_orthology)
Disease	NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE	GAPVD1 TBC1D8B NUP93	1.80e-04	30	108	3	C1868672
Disease	Depression, Bipolar	CACNA1D FSTL5 TENM4 NPAS4	2.06e-04	79	108	4	C0005587
Disease	nevus count, cutaneous melanoma	RAPGEF1 TASOR2 ARNT SYNE2	3.55e-04	91	108	4	EFO_0000389, EFO_0004632
Disease	exudative vitreoretinopathy (implicated_via_orthology)	LRP5 CDH5	3.66e-04	8	108	2	DOID:0050535 (implicated_via_orthology)
Disease	Squamous cell carcinoma of esophagus	FAT4 FAT1 EGFR NOTCH3	4.18e-04	95	108	4	C0279626
Disease	Cancer of Nasopharynx	EDNRA EGFR	4.70e-04	9	108	2	C0238301
Disease	Nasopharyngeal Neoplasms	EDNRA EGFR	4.70e-04	9	108	2	C0027439
Disease	response to angiotensin-converting enzyme inhibitor, Cough	WRN NAALADL2 CACNG4	6.46e-04	46	108	3	EFO_0005325, HP_0012735
Disease	Calcium channel blocker use measurement	CACNA1D MEX3C PLEKHG1 FAT1 AKR1B10	1.14e-03	213	108	5	EFO_0009930
Disease	obesity (implicated_via_orthology)	PNPLA2 FAT4 ZFHX4 DCHS1 NOTCH3	1.19e-03	215	108	5	DOID:9970 (implicated_via_orthology)
Disease	Agents acting on the renin-angiotensin system use measurement	CACNA1D MYO9B MEX3C PLEKHG1 AKR1B10 PCNX1	1.49e-03	335	108	6	EFO_0009931
Disease	cardiovascular disease	CACNA1D MYO9B WRN MEX3C PLEKHG1 AKR1B10 PCNX1	1.49e-03	457	108	7	EFO_0000319
Disease	Polyposis, Adenomatous Intestinal	ITIH4 EGFR	1.54e-03	16	108	2	C2713442
Disease	Familial Intestinal Polyposis	ITIH4 EGFR	1.54e-03	16	108	2	C2713443
Disease	Cerebrovascular accident	EDNRA ITM2B NOTCH3	1.54e-03	62	108	3	C0038454
Disease	protein C measurement	KCNK5 MAP3K2	1.74e-03	17	108	2	EFO_0004633
Disease	Adenomatous Polyposis Coli	ITIH4 EGFR	1.74e-03	17	108	2	C0032580
Disease	acute pancreatitis	RADX TBC1D8B	1.95e-03	18	108	2	EFO_1000652
Disease	Child Behaviour Checklist assessment	PCSK2 TENM4	1.95e-03	18	108	2	EFO_0005661
Disease	cognitive function measurement	CACNA1D DMXL2 GBF1 CNMD WRN PKD1L3 ADAMTSL3 NAALADL2 PLEKHG1 TENM4 VAV3 ARMH3 CPNE7	2.25e-03	1434	108	13	EFO_0008354
Disease	Manic Disorder	CACNA1D FSTL5 TENM4	2.27e-03	71	108	3	C0024713
Disease	unipolar depression, bipolar disorder	FAT4 FSTL5 TENM4 SYNE2	2.63e-03	156	108	4	EFO_0003761, MONDO_0004985
Disease	Ovarian Failure, Premature	HFM1 STAG3	2.66e-03	21	108	2	C0085215
Disease	Nystagmus	IDS NAALADL2	2.66e-03	21	108	2	HP_0000639
Disease	Antihypertensive use measurement	CACNA1D MYO9B EDNRA PLEKHG1 PRKCD	2.96e-03	265	108	5	EFO_0009927
Disease	Manic	CACNA1D FSTL5 TENM4	2.97e-03	78	108	3	C0338831
Disease	Glioblastoma	FAT1 EGFR NOTCH3	3.08e-03	79	108	3	C0017636
Disease	nephrotic syndrome (implicated_via_orthology)	GAPVD1 FAT1	3.48e-03	24	108	2	DOID:1184 (implicated_via_orthology)
Disease	Cancer of Head	FAT1 EGFR	3.48e-03	24	108	2	C0751177
Disease	Head Neoplasms	FAT1 EGFR	3.48e-03	24	108	2	C0018675
Disease	Upper Aerodigestive Tract Neoplasms	FAT1 EGFR	3.48e-03	24	108	2	C0887900
Disease	Colorectal Neoplasms	FAT1 ARNT EGFR AKR1B10 CDH5	3.57e-03	277	108	5	C0009404

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGDQSNSYNNEEFPD	ARNT	766	P27540
NSEVEYFISNDNHLG	FAT4	3016	Q6V0I7
AENPTASHVDNEYSQ	CD5	441	P06127
VLQSSHLEDYPFNAE	AKR1B10	301	O60218
IAEDQYANAFLHDDN	ARMH3	401	Q5T2E6
AQELLDDGQQASPYH	ELF3	166	P78545
DNPERYSTNLSNHVD	EDNRA	21	P25101
FSDTQIQEHQDPNSY	DMXL2	2491	Q8TDJ6
TNDHSPVFEQSEYRE	CELSR1	346	Q9NYQ6
NDSDYPLDLNHSETF	B4GALT5	81	O43286
NEEDAYPDNVHAAAE	SLC7A2	616	P52569
DYQDAFTIETNPAHN	CDH5	301	P33151
HEDSDSALQLQDFYQ	ITIH4	441	Q14624
EDYGESHFTVNQQPF	NUP93	446	Q8N1F7
AHDPDSQENAQVTYS	PCDHGA8	476	Q9Y5G5
QQFPDTENEEYHSDE	POTEB2	421	H3BUK9
HQDDEPVNSQYFQTT	RADX	601	Q6NSI4
LHVGDFAYNLDQDNA	ACP7	166	Q6ZNF0
QLASFLEDPQYQDQH	RELCH	1046	Q9P260
NLHSPAFLQNEYEVE	FAT1	2486	Q14517
QQFPDTENEEYHSDE	POTEF	581	A5A3E0
LDINDHAPAFNQSRY	DCHS1	246	Q96JQ0
SAQAEDYSQLPGEDH	PNPLA2	281	Q96AD5
HNDVALDSVETYNPE	KLHL33	331	A6NCF5
STSFNVQDLLPDHEY	MYLK	1386	Q15746
EVLDPEQNHNFTDHY	LONP2	461	Q86WA8
EFADSDPANIVHDFN	ITM2B	136	Q9Y287
SPRDYSNFDQEFLNE	PRKCD	626	Q05655
QAAHPQDSAFSYRDA	GAPVD1	1106	Q14C86
EASALDFDVSNNHIY	LRP5	676	O75197
VASYNNNEDAPHEPD	DYNC1I2	296	Q13409
GSDDNNLNSIFYEHL	PCNX1	1546	Q96RV3
TFNPNIDEDYDHRLA	PCNX1	1741	Q96RV3
DAQDYHPLIFQDASI	KCNK5	406	O95279
TPHFQSDSEYNFENS	DDIAS	751	Q8IXT1
PDNHQEFSDYDNPIF	MAP3K2	241	Q9Y2U5
ENDHCFPDAQSAADY	NOTCH3	1596	Q9UM47
AQNISEDFVGHLYDN	FBXO8	296	Q9NRD0
LDPEQNANFLDHYLD	LONP1	611	P36776
EYLSQSHPENRNGAD	NSMF	31	Q6X4W1
IPDQENSLDFSEHFN	ANKRD49	11	Q8WVL7
IDQNDNSPVFTHNEY	PCDH11X	561	Q9BZA7
SQYDNLEDYHSLPQH	ARHGAP32	2021	A7KAX9
YLNDFTHEIPNIQTD	IKZF5	211	Q9H5V7
LPNDDAQFDASHYDS	RBBP4	86	Q09028
DLAFQPSFTEAHQYN	FSTL5	741	Q8N475
DNIHGSAYSNDNELD	HFM1	171	A2PYH4
ENQQFPDTENEEYHS	POTEB3	456	A0JP26
QQFPDTENEEYHSDE	POTEE	581	Q6S8J3
FPYDGFTDELHQLQS	NPAS4	771	Q8IUM7
GSHQISLDNPDYQQD	EGFR	1161	P00533
ENDNHPVFTEAIYNF	DSC3	236	Q14574
SYSPDQEASFLQVHD	CACNG4	291	Q9UBN1
SAVDQDDPRNGQHFY	CDH20	516	Q9HBT6
YEVSHDFAINFNPED	CPNE7	446	Q9UBL6
PDYRQNESHNFSGDI	C1RL	326	Q9NZP8
QEQHSIDDEYAPAVF	GLMP	251	Q8WWB7
AQSDSELPSYHQNDV	GBF1	1296	Q92538
LEHSNDPFNVYIESD	KCNE1	71	P15382
YTASNPEDETQHLLF	ESCO1	626	Q5FWF5
NEAVFAADFHPTDTN	EML1	371	O00423
DSDPLQDHNMYNDSQ	IDS	526	P22304
AENHSADFDPIVYAQ	C1orf162	136	Q8NEQ5
QPEYSSQEESQHADL	CEP295	2176	Q9C0D2
LPTSEDHYDDALTQQ	ERVFC1	566	P60507
DNDLLVTELYHDPSN	KCTD3	351	Q9Y597
YIPFPEDDSNSTNHN	CACNA1D	146	Q01668
ENQQFPDTENEEYHS	POTEC	456	B2RU33
DDSIHLESIYSNFQP	MUC17	4456	Q685J3
ENQQFPDTENEEYHS	POTED	456	Q86YR6
RADPFYDEQENHSLI	KIF13B	786	Q9NQT8
FQEEDSNSDYDLQQP	RSPH4A	181	Q5TD94
EPSAHTFDDAQLQIY	RGS19	171	P49795
DQPPVDNAHYTESDQ	TEX55	331	Q96M34
IENTSHLLANPADYD	SYNE2	3801	Q8WXH0
YDNHISSLPDNVFSN	LRRC15	301	Q8TF66
LTFSNLQSDDEAEYH	IGLV4-3	96	A0A075B6K6
ESRVANLHFPNQYED	SAMD9L	461	Q8IVG5
QQFPDTENEEYHSDE	POTEB	421	A0A0A6YYL3
NIEQYIHDLDSNSFE	PDPK1	411	O15530
NAEFEEPHNYEATIS	FYB2	321	Q5VWT5
LNEENDFHYNGTDVS	MEX3C	401	Q5U5Q3
DSSANEEYEPHLFTN	SKIDA1	691	Q1XH10
VTVLADNDPSAQFHY	PKD1L3	731	Q7Z443
PESQQFPDTENEEYH	POTEJ	541	P0CG39
FPDTENEEYHSDEQN	POTEJ	546	P0CG39
SNDAYNFNLEEGVHL	SGO1	331	Q5FBB7
FYPEIQAAHASDSVQ	SELENOO	291	Q9BVL4
QSHRSDPNSESLYFE	SECISBP2L	376	Q93073
QQFPDTENEEYHSDE	POTEI	581	P0CG38
HLSPNDNENDTSYVI	WRN	451	Q14191
DRFYNNHAFEEQEPP	SPA17	66	Q15506
DEDGYTQLHFDSQSN	CLEC7A	11	Q9BXN2
EDSQAFNPDNPYHQQ	CNMD	251	O75829
SYLHFADNNELDASD	PGBD2	226	Q6P3X8
HSFNLPLSQEGEFYE	THEMIS	161	Q8N1K5
FSAADNHILPNESAY	TFDP1	146	Q14186
NDDDFEPYLSSQTNQ	YTHDF3	31	Q7Z739
DHDQSFYITDDPDDN	ZFHX4	2836	Q86UP3
HDRSFEAEINYNNPL	USP19	526	O94966
HNGEVYDETSSNLPD	USPL1	141	Q5W0Q7
TYDQDGEPIQTFHFQ	SUN2	666	Q9UH99
EDSLSPEHNYNFDIN	REV3L	1636	O60673
IQHLTEQFNEDSGDY	STAG3	161	Q9UJ98
HPSQYDNISGEDLQS	RAPGEF1	481	Q13905
NLFHEDPEEESLYQA	TBC1D8B	1001	Q0IIM8
SEDPNEQELYHATAA	TBC1D9	1041	Q6ZT07
FYSTDSSDLNENQHP	VN1R1	21	Q9GZP7
EQYPELSDSANNIHF	TENM4	2746	Q6N022
YNELQSAFHLPEQDL	SEMA5B	356	Q9P283
EDYVIISHNFTQNPD	PKHD1L1	2921	Q86WI1
PHEYEENENVFNQSS	ZNF112	386	Q9UJU3
QANNSEGSDHDYLPL	VWA5B2	1046	Q8N398
AAHNDLPENSIVNYD	TASOR2	516	Q5VWN6
SQDSLQLSEDEAPYH	PLEKHG1	786	Q9ULL1
ESQQFPDTENEQYHS	POTEG	456	Q6S5H5
QFPDTENEQYHSDEQ	POTEH	496	Q6S545
ESQQFPDTENEQYHS	POTEM	456	A6NI47
LRTASEPYHVDNFQD	TTL	221	Q8NG68
LSDDQIVNHFPNHYE	TTLL1	56	O95922
LSNIRPDYADSNFHD	VAV3	501	Q9UKW4
NDLYLDDDHISNQPF	ADAMTSL3	1041	P82987
DQRAPGHSQYLDNDD	NAALADL2	26	Q58DX5
GHSQYLDNDDLQATA	NAALADL2	31	Q58DX5
YLLDEESNFPHATSQ	MYO9B	591	Q13459
DYLHPDLASNYNAEA	PCSK2	171	P16519