Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cysteine-type exopeptidase activity	SCRN3 SCRN1 SCRN2	1.56e-05	10	103	3	GO:0070004
GeneOntologyMolecularFunction	dipeptidase activity	SCRN3 SCRN1 SCRN2	1.03e-04	18	103	3	GO:0016805
GeneOntologyMolecularFunction	alkylglycerophosphoethanolamine phosphodiesterase activity	ENPP2 GNB1	2.61e-04	5	103	2	GO:0047391
GeneOntologyMolecularFunction	metalloendopeptidase activity	ADAMTS3 ADAMTS1 ADAM23 ADAM8 ADAMTS14	3.95e-04	120	103	5	GO:0004222
GeneOntologyMolecularFunction	peptidase activity	RELN SCRN3 ADAMTS3 ADAMTS1 ADAM23 SCRN1 ADAM8 SCRN2 USP32 ADAMTS14 USP47	5.56e-04	654	103	11	GO:0008233
Domain	Peptidase_C69	SCRN3 SCRN1 SCRN2	1.53e-07	3	101	3	PF03577
Domain	Peptidase_C69	SCRN3 SCRN1 SCRN2	1.53e-07	3	101	3	IPR005322
Domain	Guanine_nucleotide-bd_bsu	GNB4 GNB1 GNB2	1.52e-06	5	101	3	IPR016346
Domain	Pep_M12B_propep	ADAMTS3 ADAMTS1 ADAM23 ADAM8 ADAMTS14	2.08e-06	39	101	5	PF01562
Domain	Peptidase_M12B_N	ADAMTS3 ADAMTS1 ADAM23 ADAM8 ADAMTS14	2.08e-06	39	101	5	IPR002870
Domain	DISINTEGRIN_1	ADAMTS3 ADAMTS1 ADAM23 ADAM8 ADAMTS14	2.37e-06	40	101	5	PS00427
Domain	Reprolysin	ADAMTS3 ADAMTS1 ADAM23 ADAM8 ADAMTS14	2.37e-06	40	101	5	PF01421
Domain	ADAM_MEPRO	ADAMTS3 ADAMTS1 ADAM23 ADAM8 ADAMTS14	2.37e-06	40	101	5	PS50215
Domain	DISINTEGRIN_2	ADAMTS3 ADAMTS1 ADAM23 ADAM8 ADAMTS14	2.37e-06	40	101	5	PS50214
Domain	Peptidase_M12B	ADAMTS3 ADAMTS1 ADAM23 ADAM8 ADAMTS14	2.37e-06	40	101	5	IPR001590
Domain	Disintegrin_dom	ADAMTS3 ADAMTS1 ADAM23 ADAM8 ADAMTS14	2.69e-06	41	101	5	IPR001762
Domain	ADAM_Cys-rich	ADAMTS1 ADAM23 ADAM8 ADAMTS14	1.28e-05	27	101	4	IPR006586
Domain	ACR	ADAMTS1 ADAM23 ADAM8 ADAMTS14	1.28e-05	27	101	4	SM00608
Domain	Gprotein_B	GNB4 GNB1 GNB2	1.79e-05	10	101	3	IPR001632
Domain	Arm	RAP1GDS1 ODAD2 CTNND2 ARMC6	2.27e-05	31	101	4	PF00514
Domain	-	IPO5 RAP1GDS1 RANBP6 ODAD2 CTNNBL1 CTNND2 HEATR5B ARMC6	2.75e-05	222	101	8	1.25.10.10
Domain	ARM_REPEAT	RAP1GDS1 ODAD2 CTNND2 ARMC6	6.34e-05	40	101	4	PS50176
Domain	ARM	RAP1GDS1 ODAD2 CTNND2 ARMC6	6.34e-05	40	101	4	SM00185
Domain	-	ADAMTS3 ADAMTS1 ADAM23 ADAM8 ADAMTS14	7.74e-05	81	101	5	3.40.390.10
Domain	MetalloPept_cat_dom	ADAMTS3 ADAMTS1 ADAM23 ADAM8 ADAMTS14	7.74e-05	81	101	5	IPR024079
Domain	ARM-like	IPO5 RAP1GDS1 RANBP6 ODAD2 CTNNBL1 CTNND2 HEATR5B ARMC6	1.09e-04	270	101	8	IPR011989
Domain	Armadillo	RAP1GDS1 ODAD2 CTNND2 ARMC6	1.20e-04	47	101	4	IPR000225
Domain	ADAM_spacer1	ADAMTS3 ADAMTS1 ADAMTS14	2.51e-04	23	101	3	IPR010294
Domain	ADAM_spacer1	ADAMTS3 ADAMTS1 ADAMTS14	2.51e-04	23	101	3	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS3 ADAMTS1 ADAMTS14	2.86e-04	24	101	3	IPR013273
Domain	EGF_extracell	RELN ADAM23 ADAM8 SVEP1	3.11e-04	60	101	4	IPR013111
Domain	EGF_2	RELN ADAM23 ADAM8 SVEP1	3.11e-04	60	101	4	PF07974
Domain	TSP_1	CILP ADAMTS3 ADAMTS1 ADAMTS14	3.76e-04	63	101	4	PF00090
Domain	TSP1	CILP ADAMTS3 ADAMTS1 ADAMTS14	4.23e-04	65	101	4	SM00209
Domain	TSP1_rpt	CILP ADAMTS3 ADAMTS1 ADAMTS14	4.23e-04	65	101	4	IPR000884
Domain	TSP1	CILP ADAMTS3 ADAMTS1 ADAMTS14	4.23e-04	65	101	4	PS50092
Domain	-	SEMA6C WDR19 EML5 GNB4 ELP2 GNB1 GNB2 PLXNB1	4.50e-04	333	101	8	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	SEMA6C WDR19 EML5 GNB4 ELP2 GNB1 GNB2 PLXNB1	4.68e-04	335	101	8	IPR015943
Domain	ARM-type_fold	IPO5 RAP1GDS1 RANBP6 ODAD2 CTNNBL1 CTNND2 HEATR5B ARMC6	5.07e-04	339	101	8	IPR016024
Domain	HEAT_REPEAT	IPO5 RANBP6 ODAD2 HEATR5B	5.62e-04	70	101	4	PS50077
Domain	PH_dom-spectrin-type	SPTBN5 PSD4	1.02e-03	9	101	2	IPR001605
Domain	Tyr_kinase_rcpt_2_CS	DDR2 IGF1R	1.54e-03	11	101	2	IPR002011
Domain	RECEPTOR_TYR_KIN_II	DDR2 IGF1R	1.84e-03	12	101	2	PS00239
Domain	ZINC_PROTEASE	ADAMTS3 ADAMTS1 ADAM8 ADAMTS14	1.97e-03	98	101	4	PS00142
Domain	WD40	WDR19 EML5 GNB4 ELP2 GNB1 GNB2	2.84e-03	259	101	6	PF00400
Domain	WD40	WDR19 EML5 GNB4 ELP2 GNB1 GNB2	3.36e-03	268	101	6	SM00320
Domain	WD40_repeat	WDR19 EML5 GNB4 ELP2 GNB1 GNB2	3.61e-03	272	101	6	IPR001680
Domain	HEAT	IPO5 RANBP6 ODAD2	3.82e-03	58	101	3	IPR000357
Domain	WD_REPEATS_1	WDR19 EML5 GNB4 ELP2 GNB1 GNB2	4.01e-03	278	101	6	PS00678
Domain	WD_REPEATS_2	WDR19 EML5 GNB4 ELP2 GNB1 GNB2	4.08e-03	279	101	6	PS50082
Domain	WD_REPEATS_REGION	WDR19 EML5 GNB4 ELP2 GNB1 GNB2	4.08e-03	279	101	6	PS50294
Domain	ADAM_CR	ADAM23 ADAM8	4.19e-03	18	101	2	PF08516
Domain	PLAC	ADAMTS3 ADAMTS14	4.66e-03	19	101	2	PS50900
Domain	PLAC	ADAMTS3 ADAMTS14	4.66e-03	19	101	2	IPR010909
Domain	-	ADAM23 ADAM8	5.16e-03	20	101	2	4.10.70.10
Domain	CH	SPTBN5 DST DIXDC1	5.26e-03	65	101	3	SM00033
Domain	-	SHC4 PLCD4 SPTBN5 DGKK GAB3 FAM43A PSD4	5.33e-03	391	101	7	2.30.29.30
Pathway	REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR	GNB4 GNB1 GNB2	1.48e-04	19	78	3	MM15021
Pathway	REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR	GNB4 GNB1 GNB2	1.48e-04	19	78	3	M926
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42	GNB4 GNB1 GNB2	1.74e-04	20	78	3	MM15572
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42	GNB4 GNB1 GNB2	1.74e-04	20	78	3	M27853
Pathway	REACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS	GNB4 GNB1 GNB2	2.02e-04	21	78	3	M27409
Pathway	REACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS	GNB4 GNB1 GNB2	2.02e-04	21	78	3	MM15159
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12	GNB4 GNB1 GNB2	2.33e-04	22	78	3	MM15016
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12	GNB4 GNB1 GNB2	2.33e-04	22	78	3	M841
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	ADAMTS3 ADAMTS1 DDR2 ADAM8 TGFB3 DST LOXL2 ADAMTS14	2.47e-04	300	78	8	M610
Pathway	REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION	GNB4 GNB1 GNB2	2.66e-04	23	78	3	MM15033
Pathway	KEGG_MEDICUS_REFERENCE_LPAR_GNB_G_RHO_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	2.66e-04	23	78	3	M47549
Pathway	REACTOME_G_PROTEIN_ACTIVATION	GNB4 GNB1 GNB2	3.03e-04	24	78	3	M13115
Pathway	REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR	GNB4 GNB1 GNB2	3.03e-04	24	78	3	MM15088
Pathway	REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR	GNB4 GNB1 GNB2	3.03e-04	24	78	3	M18308
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	3.03e-04	24	78	3	M47460
Pathway	REACTOME_G_PROTEIN_ACTIVATION	GNB4 GNB1 GNB2	3.03e-04	24	78	3	MM14794
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1	GNB4 GNB1 GNB2	3.43e-04	25	78	3	MM15056
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1	GNB4 GNB1 GNB2	3.43e-04	25	78	3	M811
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA	GNB4 GNB1 GNB2	3.43e-04	25	78	3	M14301
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA	GNB4 GNB1 GNB2	3.87e-04	26	78	3	MM15017
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	3.87e-04	26	78	3	M47561
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	3.87e-04	26	78	3	M47562
Pathway	KEGG_MEDICUS_REFERENCE_CCR5_GNB_G_PLCB_G_PKC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	3.87e-04	26	78	3	M47557
Pathway	KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_PI3K_AKT_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	3.87e-04	26	78	3	M47456
Pathway	KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_ERK_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	4.33e-04	27	78	3	M47454
Pathway	REACTOME_GPER1_SIGNALING	GNB4 GNB1 GNB2	4.33e-04	27	78	3	MM15664
Pathway	KEGG_MEDICUS_PATHOGEN_SHIGELLA_FIMA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS	HKDC1 VDAC1	4.47e-04	6	78	2	M47654
Pathway	REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION	GNB4 GNB1 GNB2	4.83e-04	28	78	3	M10679
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_JNK_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	5.37e-04	29	78	3	M47466
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS3 ADAMTS1 GALNT12 ADAMTS14	5.40e-04	68	78	4	M27303
Pathway	REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING	GNB4 GNB1 GNB2	5.94e-04	30	78	3	M18193
Pathway	REACTOME_ACTIVATION_OF_G_PROTEIN_GATED_POTASSIUM_CHANNELS	GNB4 GNB1 GNB2	5.94e-04	30	78	3	MM14542
Pathway	REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING	IGF1R GNB4 GNB1 GNB2	6.36e-04	71	78	4	MM15590
Pathway	REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS	GNB4 GNB1 GNB2	6.55e-04	31	78	3	MM15094
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	6.55e-04	31	78	3	M47554
Pathway	KEGG_MEDICUS_REFERENCE_CCR_CXCR_GNB_G_PI3K_RAC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	6.55e-04	31	78	3	M47455
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_ERK_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	6.55e-04	31	78	3	M47459
Pathway	KEGG_MEDICUS_REFERENCE_CCR2_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	6.55e-04	31	78	3	M47540
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	6.55e-04	31	78	3	M47541
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	GNB4 GNB1 GNB2	7.20e-04	32	78	3	M861
Pathway	REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING	GNB4 GNB1 GNB2	7.20e-04	32	78	3	M14309
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	GNB4 GNB1 GNB2	7.20e-04	32	78	3	MM15148
Pathway	REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING	GNB4 GNB1 GNB2	7.20e-04	32	78	3	MM15143
Pathway	KEGG_MEDICUS_REFERENCE_GPCR_PI3K_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	7.20e-04	32	78	3	M47962
Pathway	REACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION	GNB4 GNB1 GNB2	7.20e-04	32	78	3	MM14983
Pathway	REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING	IGF1R GNB4 GNB1 GNB2	7.83e-04	75	78	4	M27874
Pathway	REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING	GNB4 GNB1 GNB2	7.89e-04	33	78	3	MM15027
Pathway	REACTOME_SIGNAL_AMPLIFICATION	GNB4 GNB1 GNB2	7.89e-04	33	78	3	MM15020
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	GNB4 GNB1 GNB2	7.89e-04	33	78	3	MM15058
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY	GNB4 GNB1 GNB2	7.89e-04	33	78	3	M47550
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	GNB4 GNB1 GNB2	7.89e-04	33	78	3	MM15066
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	GNB4 GNB1 GNB2	7.89e-04	33	78	3	M10322
Pathway	REACTOME_SIGNAL_AMPLIFICATION	GNB4 GNB1 GNB2	7.89e-04	33	78	3	M9379
Pathway	REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION	GNB4 GNB1 GNB2	7.89e-04	33	78	3	M11575
Pathway	REACTOME_PLATELET_HOMEOSTASIS	PAFAH2 GNB4 GNB1 GNB2	8.23e-04	76	78	4	MM15051
Pathway	REACTOME_ESR_MEDIATED_SIGNALING	POLR2B IGF1R GNB4 GNB1 GNB2	8.43e-04	133	78	5	MM15529
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	GNB4 GNB1 GNB2 PLXNB1	8.64e-04	77	78	4	MM15044
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	GNB4 GNB1 GNB2	9.39e-04	35	78	3	M1075
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	GNB4 GNB1 GNB2 PLXNB1	9.98e-04	80	78	4	M800
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	GNB4 GNB1 GNB2	1.02e-03	36	78	3	MM14544
Pathway	REACTOME_COOPERATION_OF_PDCL_PHLP1_AND_TRIC_CCT_IN_G_PROTEIN_BETA_FOLDING	GNB4 GNB1 GNB2	1.20e-03	38	78	3	M27656
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS3 ADAMTS1 ADAMTS14	1.29e-03	39	78	3	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS3 ADAMTS1 ADAMTS14	1.29e-03	39	78	3	MM15165
Pathway	REACTOME_CHAPERONIN_MEDIATED_PROTEIN_FOLDING	GNB4 GNB1 GNB2	1.29e-03	39	78	3	MM15003
Pathway	REACTOME_PLATELET_HOMEOSTASIS	PAFAH2 GNB4 GNB1 GNB2	1.31e-03	86	78	4	M916
Pathway	REACTOME_AQUAPORIN_MEDIATED_TRANSPORT	GNB4 GNB1 GNB2	1.39e-03	40	78	3	MM15115
Pathway	REACTOME_COLLAGEN_FORMATION	ADAMTS3 DST LOXL2 ADAMTS14	1.55e-03	90	78	4	M631
Pathway	REACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION	GNB4 GNB1 GNB2	1.60e-03	42	78	3	M791
Pathway	REACTOME_ADORA2B_MEDIATED_ANTI_INFLAMMATORY_CYTOKINES_PRODUCTION	GNB4 GNB1 GNB2	1.72e-03	43	78	3	M29837
Pathway	REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS	GNB4 GNB1 GNB2	1.72e-03	43	78	3	M933
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2	1.72e-03	43	78	3	M954
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2	1.83e-03	44	78	3	MM15709
Pathway	REACTOME_CA2_PATHWAY	GNB4 GNB1 GNB2	1.96e-03	45	78	3	MM15040
Pathway	REACTOME_GPER1_SIGNALING	GNB4 GNB1 GNB2	1.96e-03	45	78	3	M45008
Pathway	KEGG_MEDICUS_REFERENCE_IGF_IGF1R_PI3K_SIGNALING_PATHWAY	TSC1 IGF1R	2.27e-03	13	78	2	M47603
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	GNB4 GNB1 GNB2	2.36e-03	48	78	3	M10775
Pathway	WP_SEROTONIN_AND_ANXIETYRELATED_EVENTS	HTR2A PLCD4	2.63e-03	14	78	2	M39614
Pathway	WP_MODULATION_OF_PI3KAKTMTOR_SIGNALING_BY_BIOACTIVE_SPHINGOLIPIDS	TSC1 IGF1R	2.63e-03	14	78	2	M45553
Pathway	WP_PI3KAKT_SIGNALING	RELN TSC1 IGF1R BRCA1 GNB4 GNB1 GNB2	2.68e-03	339	78	7	M39736
Pathway	REACTOME_AQUAPORIN_MEDIATED_TRANSPORT	GNB4 GNB1 GNB2	2.96e-03	52	78	3	M920
Pathway	KEGG_MEDICUS_REFERENCE_RELN_VLDLR_PI3K_SIGNALING_PATHWAY	RELN TSC1	3.03e-03	15	78	2	M47663
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	ADAMTS3 DDR2 ADAM8 TGFB3 LOXL2 ADAMTS14	3.03e-03	258	78	6	MM14572
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS3 ADAMTS1 GALNT12 ADAMTS14	3.11e-03	109	78	4	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS3 ADAMTS1 GALNT12 ADAMTS14	3.32e-03	111	78	4	M27416
Pathway	WP_RAS_SIGNALING	SHC4 IGF1R GNB4 GNB1 GNB2	3.51e-03	184	78	5	M39764
Pathway	WP_SEROTONIN_AND_ANXIETY	HTR2A PLCD4	3.90e-03	17	78	2	M39511
Pathway	REACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS	POLR2B IGF1R GNB4 GNB1 GNB2	4.11e-03	191	78	5	MM15586
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2	4.45e-03	60	78	3	MM15708
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	GNB4 GNB1 GNB2	4.45e-03	60	78	3	MM14964
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2	4.45e-03	60	78	3	M976
Pathway	REACTOME_REGULATION_OF_INSULIN_SECRETION	GNB4 GNB1 GNB2	4.66e-03	61	78	3	MM15071
Pubmed	Purification and identification of secernin, a novel cytosolic protein that regulates exocytosis in mast cells.	SCRN3 SCRN1 SCRN2	2.52e-08	3	103	3	12221138
Pubmed	Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA.	GNB4 GNB1 GNB2	1.01e-07	4	103	3	1543505
Pubmed	The role of G protein beta subunits in the release of ATP from human erythrocytes.	GNB4 GNB1 GNB2	1.01e-07	4	103	3	12512701
Pubmed	The Sertoli cell expressed gene secernin-1 (Scrn1) is dispensable for male fertility in the mouse.	SCRN3 SCRN1 SCRN2	2.51e-07	5	103	3	33442887
Pubmed	Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors.	GNB4 GNB1 GNB2	5.01e-07	6	103	3	16371464
Pubmed	Identification of Gnr1p, a negative regulator of G alpha signalling in Schizosaccharomyces pombe, and its complementation by human G beta subunits.	GNB4 GNB1 GNB2	5.01e-07	6	103	3	16884933
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	IPO5 RELN RAP1GDS1 TTC28 MYO1E ADAMTS1 ADAM23 ENPP2 RAD54L2 WDR19 DST USP32 YY1AP1 CTNND2 GNB1 USP47	1.20e-06	1285	103	16	35914814
Pubmed	The gene for the beta-subunit of retinal transducin (Gnb-1) maps to distal mouse chromosome 4, and related sequences map to mouse chromosomes 5 and 8.	GNB4 GNB1 GNB2	1.40e-06	8	103	3	2328987
Pubmed	Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11.	GNB4 GNB1 GNB2	2.09e-06	9	103	3	10339615
Pubmed	Gβ2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex.	GNB4 GNB1 GNB2	2.98e-06	10	103	3	28334111
Pubmed	Expression of olfactory receptors, G-proteins and AxCAMs during the development and maturation of olfactory sensory neurons in the mouse.	GNB4 GNB1 GNB2	2.98e-06	10	103	3	9733924
Pubmed	The G protein subunit gene families.	GNB4 GNB1 GNB2	4.09e-06	11	103	3	10644457
Pubmed	Specificities of Gβγ subunits for the SNARE complex before and after stimulation of α2a-adrenergic receptors.	GNB4 GNB1 GNB2	4.09e-06	11	103	3	34932372
Pubmed	A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation.	GNB4 GNB1 GNB2	4.09e-06	11	103	3	25982117
Pubmed	Human Multisubunit E3 Ubiquitin Ligase Required for Heterotrimeric G-Protein β-Subunit Ubiquitination and Downstream Signaling.	GNB4 GNB1 GNB2	5.44e-06	12	103	3	34342229
Pubmed	Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice.	GNB4 GNB1 GNB2	5.44e-06	12	103	3	20186915
Pubmed	Differential sensitivity of P-Rex1 to isoforms of G protein betagamma dimers.	GNB4 GNB1 GNB2	5.44e-06	12	103	3	16301321
Pubmed	Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families.	GNB4 GNB1 GNB2	5.44e-06	12	103	3	8636150
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	IPO5 CAD TTC28 POLR2B RANBP6 RNF213 TSC1 SPTBN5 GET4 DST ATAD1 GNB4 GNB1 SMCR8 USP47 VDAC1	8.32e-06	1496	103	16	32877691
Pubmed	Different roles of G protein subunits beta1 and beta2 in neutrophil function revealed by gene expression silencing in primary mouse neutrophils.	GNB1 GNB2	8.69e-06	2	103	2	20525682
Pubmed	Expression of inflammatory and fibrogenetic markers in acne hypertrophic scar formation: focusing on role of TGF-β and IGF-1R.	TGFB3 IGF1R	8.69e-06	2	103	2	30167815
Pubmed	Fibrotic Response of Human Trabecular Meshwork Cells to Transforming Growth Factor-Beta 3 and Autotaxin in Aqueous Humor.	ENPP2 TGFB3	8.69e-06	2	103	2	36139071
Pubmed	Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta.	GNB4 GNB1 GNB2	1.12e-05	15	103	3	12486123
Pubmed	ADAMTS2 promotes radial migration by activating TGF-β signaling in the developing neocortex.	ADAMTS3 ADAMTS1 ADAMTS14	1.12e-05	15	103	3	38871984
Pubmed	Role of molecular chaperones in G protein beta5/regulator of G protein signaling dimer assembly and G protein betagamma dimer specificity.	GNB4 GNB1 GNB2	1.66e-05	17	103	3	19376773
Pubmed	Reelin influences the expression and function of dopamine D2 and serotonin 5-HT2A receptors: a comparative study.	RELN HTR2A	2.60e-05	3	103	2	25637489
Pubmed	Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3.	ADAMTS3 ADAMTS14	2.60e-05	3	103	2	11741898
Pubmed	Endogenous hydrogen sulfide production is essential for dietary restriction benefits.	TSC1 CTH	2.60e-05	3	103	2	25542313
Pubmed	IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy.	IGFBPL1 IGF1R	2.60e-05	3	103	2	37527036
Pubmed	Mutations in G protein β subunits promote transformation and kinase inhibitor resistance.	GNB1 GNB2	2.60e-05	3	103	2	25485910
Pubmed	Elevated insulin-like growth factor-I receptor (IGF-IR) levels in primary breast tumors associated with BRCA1 mutations.	IGF1R BRCA1	2.60e-05	3	103	2	17766039
Pubmed	The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology.	ADAMTS3 ADAMTS14	2.60e-05	3	103	2	25863161
Pubmed	Selective association of G protein beta(4) with gamma(5) and gamma(12) subunits in bovine tissues.	GNB4 GNB2	2.60e-05	3	103	2	10409705
Pubmed	Genomic organization of the murine G protein beta subunit genes and related processed pseudogenes.	GNB1 GNB2	2.60e-05	3	103	2	11913780
Pubmed	G protein beta gamma subunits. Simplified purification and properties of novel isoforms.	GNB1 GNB2	2.60e-05	3	103	2	8308009
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ATP7B MYL6 TTC28 ADAMTS1 POLR2B RNF213 ABCA7 EML5 BRCA1 CTNNBL1 EHMT1 ARMC6 SP140	2.64e-05	1116	103	13	31753913
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	IPO5 MYL6 TTC28 ADAMTS1 PGD GET4 BRCA1 ATAD1 USP32 MTCL1 GNB2 USP47	4.35e-05	1005	103	12	19615732
Pubmed	KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression.	GNB4 GNB1 GNB2	4.88e-05	24	103	3	23209302
Pubmed	Expression of ADAMTS-2, -3, -13, and -14 in culprit coronary lesions in patients with acute myocardial infarction or stable angina.	ADAMTS3 ADAMTS14	5.19e-05	4	103	2	22205175
Pubmed	Functional and physical interactions between BRCA1 and p53 in transcriptional regulation of the IGF-IR gene.	IGF1R BRCA1	5.19e-05	4	103	2	14710355
Pubmed	G protein beta interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus.	GNB1 GNB2	5.19e-05	4	103	2	15955845
Pubmed	ADAMTS: a novel family of proteases with an ADAM protease domain and thrombospondin 1 repeats.	ADAMTS3 ADAMTS1	5.19e-05	4	103	2	10094461
Pubmed	The cationic region of Rhes mediates its interactions with specific Gbeta subunits.	GNB1 GNB2	5.19e-05	4	103	2	19255495
Pubmed	G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development.	GNB4 GNB1 GNB2	7.83e-05	28	103	3	8858601
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	IPO5 CRYBG2 MYL6 TTC28 PLCD4 ZMAT3 CTNNBL1 EHMT1	8.00e-05	469	103	8	27634302
Pubmed	Gbeta gamma isoforms selectively rescue plasma membrane localization and palmitoylation of mutant Galphas and Galphaq.	GNB4 GNB1	8.64e-05	5	103	2	11294873
Pubmed	[ADAMTS family--new extracellular matrix degrading enzyme].	ADAMTS3 ADAMTS1	8.64e-05	5	103	2	11831030
Pubmed	Mitogen-activated protein kinase activation requires two signal inputs from the human anaphylatoxin C5a receptor.	GNB1 GNB2	8.64e-05	5	103	2	7649993
Pubmed	Glucagon and regulation of glucose metabolism.	GNB4 GNB1 GNB2	1.07e-04	31	103	3	12626323
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	IPO5 CAD MYL6 POLR2B SCRN1 PGD DST LOXL2 EHMT1 GNB4 MTCL1 ATG9A ARMC6	1.21e-04	1297	103	13	33545068
Pubmed	mTORC1 impedes osteoclast differentiation via calcineurin and NFATc1.	RELN TSC1	1.29e-04	6	103	2	30271915
Pubmed	Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits.	GNB1 GNB2	1.29e-04	6	103	2	7665596
Pubmed	Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors.	GNB1 GNB2	1.29e-04	6	103	2	9238069
Pubmed	Regulation of procollagen amino-propeptide processing during mouse embryogenesis by specialization of homologous ADAMTS proteases: insights on collagen biosynthesis and dermatosparaxis.	ADAMTS3 ADAMTS14	1.29e-04	6	103	2	16556917
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	CAD MYL6 TTC28 MYO1E RNF213 PGD	1.52e-04	268	103	6	33024031
Pubmed	Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium.	GNB4 GNB1	1.81e-04	7	103	2	10570481
Pubmed	Activation of the PI3K/AKT/mTOR Pathway in Cajal-Retzius Cells Leads to Their Survival and Increases Susceptibility to Kainate-Induced Seizures.	RELN TSC1	1.81e-04	7	103	2	36982451
Pubmed	Abundance of ADAM-8, -9, -10, -12, -15 and -17 and ADAMTS-1 in mouse uterus during the oestrous cycle.	ADAMTS1 ADAM8	1.81e-04	7	103	2	15907280
Pubmed	The Secreted Glycoprotein Reelin Suppresses the Proliferation and Regulates the Distribution of Oligodendrocyte Progenitor Cells in the Embryonic Neocortex.	RELN ADAMTS3	1.81e-04	7	103	2	32913108
Pubmed	Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia.	SCRN1 GNB1 GNB2	2.30e-04	40	103	3	20381070
Pubmed	A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits.	GNB1 GNB2	2.40e-04	8	103	2	9789084
Pubmed	Gβγ interacts with mTOR and promotes its activation.	GNB1 GNB2	2.40e-04	8	103	2	24462769
Pubmed	Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin.	RELN ADAMTS3	2.40e-04	8	103	2	28213441
Pubmed	Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers.	IGF1R BRCA1	2.40e-04	8	103	2	19843326
Pubmed	Comparative analysis of the signaling capabilities of the insulin receptor-related receptor.	KRT27 IGF1R	2.40e-04	8	103	2	15629149
Pubmed	The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety.	GNB4 GNB1 GNB2	2.86e-04	43	103	3	26487511
Pubmed	Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.	IPO5 CAD RAD54L2 ZMAT3	2.86e-04	106	103	4	19394292
Pubmed	The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons.	RELN TGFB3 IGF1R	3.06e-04	44	103	3	27224923
Pubmed	A disintegrin and metalloproteinase with thrombospondin motifs 2 cleaves and inactivates Reelin in the postnatal cerebral cortex and hippocampus, but not in the cerebellum.	RELN ADAMTS3	3.08e-04	9	103	2	31491533
Pubmed	Ataxin 10 induces neuritogenesis via interaction with G-protein beta2 subunit.	GNB1 GNB2	3.08e-04	9	103	2	16498633
Pubmed	Spontaneous and induced mouse mutations with cerebellar dysfunctions: behavior and neurochemistry.	RELN DST	3.08e-04	9	103	2	16499884
Pubmed	Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network.	CAD POLR2B GET4 GNB1	3.41e-04	111	103	4	32683582
Pubmed	Characterization of LGALS3 (galectin-3) as a player in DNA damage response.	IPO5 MYL6 BRCA1	3.49e-04	46	103	3	24755837
Pubmed	Fine mapping of the human and mouse genes for the type I procollagen COOH-terminal proteinase enhancer protein.	ZP3 GNB2	3.85e-04	10	103	2	8824813
Pubmed	Peripheral macrophage abnormalities in mutant mice with spinocerebellar degeneration.	RELN DST	3.85e-04	10	103	2	1565842
Pubmed	Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.	IGF1R BRCA1 HPGDS EHMT1	4.16e-04	117	103	4	19124506
Pubmed	Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub.	ADAM23 GNB4 GNB1 GNB2 VDAC1	4.62e-04	215	103	5	36808153
Pubmed	Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor-mediated chemotaxis.	GNB1 GNB2	4.69e-04	11	103	2	32332099
Pubmed	Developmental expression of heterotrimeric G-proteins in the murine cerebellar cortex.	GNB1 GNB2	4.69e-04	11	103	2	11685543
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	ADAMTS1 POLR2B RANBP6 GALNT12 GET4 ATAD1 CTH GNB1 HEATR5B VDAC1	4.93e-04	942	103	10	31073040
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	IPO5 CAD MYL6 MYO1E PARP2 POLR2B SHC4 DST GNB1 GNB2	5.22e-04	949	103	10	36574265
Pubmed	Cellular redox sensor HSCARG negatively regulates the translesion synthesis pathway and exacerbates mammary tumorigenesis.	ATAD1 GNB4 GNB1 GNB2 VDAC1	5.23e-04	221	103	5	31796584
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	IPO5 MYL6 IGF1R DST GNB4 GNB1 GNB2 VDAC1	5.31e-04	621	103	8	22794259
Pubmed	Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair.	POLR2B BRCA1	5.62e-04	12	103	2	28700933
Pubmed	Conditional stimulation of type V and VI adenylyl cyclases by G protein betagamma subunits.	GNB1 GNB2	5.62e-04	12	103	2	17110384
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	TTC28 WDR19 ASXL3 EHMT1 MTCL1 CTNND2 SMCR8 USP47	6.34e-04	638	103	8	31182584
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	IPO5 CAD MYL6 SCRN1 TSC1 PGD GNB1 GNB2 VDAC1	6.48e-04	803	103	9	36517590
Pubmed	BRCA1 interaction with RNA polymerase II reveals a role for hRPB2 and hRPB10alpha in activated transcription.	POLR2B BRCA1	6.63e-04	13	103	2	10725406
Pubmed	The human G protein beta4 subunit: gene structure, expression, Ggamma and effector interaction.	GNB4 GNB1	6.63e-04	13	103	2	12782285
Pubmed	Cloning and chromosomal mapping of mouse ADAM11, ADAM22 and ADAM23.	ADAM23 BRCA1	6.63e-04	13	103	2	10433968
Pubmed	Defining the membrane proteome of NK cells.	IPO5 CAD ATP7B MYL6 RNF213 ATAD1 CTNNBL1 ATG9A GNB2 HEATR5B PSD4	6.96e-04	1168	103	11	19946888
Pubmed	Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.	ADAMTS3 POLR2B PLCD4 IGF1R	7.33e-04	136	103	4	25429064
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	MYL6 MYO1E POLR2B BRCA1 GNB1 GNB2	7.37e-04	361	103	6	30344098
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	MYO1E ASXL3 HERC3 MTCL1 CTNND2 FAM43A	7.37e-04	361	103	6	26167880
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	ATP7B TSC1 DST USP32 ATG9A HEATR5B SMCR8	7.71e-04	504	103	7	34432599
Pubmed	Gbeta3 forms distinct dimers with specific Ggamma subunits and preferentially activates the beta3 isoform of phospholipase C.	GNB1 GNB2	7.72e-04	14	103	2	19168127
Pubmed	Syntenic assignment of human chromosome 1 homologous loci in the bovine.	PGD GNB1	7.72e-04	14	103	2	8001974
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	CAD MYL6 TTC28 DDR2 PGD DST ASXL3	8.54e-04	513	103	7	25798074
Pubmed	Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator.	GLRX5 EHMT1 CDYL2	8.80e-04	63	103	3	25680957
Pubmed	Interaction of G-protein βγ complex with chromatin modulates GPCR-dependent gene regulation.	GNB1 GNB2	8.89e-04	15	103	2	23326349
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	RAP1GDS1 ODAD2 CTNND2 ARMC6	1.91e-05	43	67	4	409
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS3 ADAMTS1 ADAMTS14	4.52e-05	19	67	3	50
GeneFamily	WD repeat domain containing	WDR19 EML5 GNB4 ELP2 GNB1 GNB2	4.16e-04	262	67	6	362
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BOC HTR2A ADAMTS1 ENPP2 DDR2 TGFB3 LOXL2	3.60e-07	195	103	7	c6bb16c0076639c6ddef1a15d8cba44bc29c077d
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BOC HTR2A ADAMTS1 ENPP2 DDR2 TGFB3 LOXL2	3.60e-07	195	103	7	ea89f80d3d7e9f737442f7c1aa1791d277ffc90c
ToppCell	P15-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CAD ADAM23 GALNT12 ABCA7 WDR19 HEATR5B	2.54e-06	167	103	6	5c3d0763f73628c71c71f9883556bb4f1639f3cc
ToppCell	356C-Fibroblasts-Fibroblast-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	BOC HTR2A ADAMTS3 DDR2 SVEP1 TGFB3	3.67e-06	178	103	6	a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell	356C-Fibroblasts-Fibroblast-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	BOC HTR2A ADAMTS3 DDR2 SVEP1 TGFB3	3.67e-06	178	103	6	371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTR2A ADAMTS3 ENPP2 TGFB3 LOXL2 PLXNB1	3.91e-06	180	103	6	d67d3196e6cc3dcd31023a4dc69310226181d583
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTR2A ADAMTS3 ENPP2 TGFB3 LOXL2 PLXNB1	3.91e-06	180	103	6	573308d43425d9fba20787abdb7f8efefc48efb5
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	ENPP2 DDR2 TGFB3 DST LOXL2 ADAMTS14	4.17e-06	182	103	6	812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC CILP ADAMTS3 ADAMTS1 DDR2 SVEP1	4.58e-06	185	103	6	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	facs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC ENPP2 DDR2 TGFB3 LOXL2 DIXDC1	5.33e-06	190	103	6	c7bd087f36321cec61b98657433b4d19d135791f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC ENPP2 DDR2 TGFB3 LOXL2 DIXDC1	5.33e-06	190	103	6	834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BOC CILP DDR2 SVEP1 TGFB3 LOXL2	5.50e-06	191	103	6	b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-NK\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADAMTS1 ENPP2 BRCA1 EHMT1 PLXNB1 SP140	5.66e-06	192	103	6	930319cbd82b9e54864147ffcdc8bd0ea7b937be
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADAMTS1 ENPP2 BRCA1 EHMT1 PLXNB1 SP140	5.66e-06	192	103	6	c7bcebcb88a25b2c97d798120efa9d5958e7f798
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-3\|TCGA-Stomach / Sample_Type by Project: Shred V9	BOC HTR2A CILP DDR2 SVEP1 TGFB3	6.01e-06	194	103	6	2260cd817a6661e5eb6645b0c6786e18fd58371e
ToppCell	facs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC CILP ADAMTS1 DDR2 SVEP1 LOXL2	6.19e-06	195	103	6	69a29d03e664b72f32d41876510c62345c3aed31
ToppCell	facs-GAT-Fat-3m-Mesenchymal\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC CILP ADAMTS1 DDR2 SVEP1 LOXL2	6.19e-06	195	103	6	1cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCell	facs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC CILP ADAMTS1 DDR2 SVEP1 LOXL2	6.19e-06	195	103	6	9cef6f18664518060af7c192310dddce6d70345a
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	BOC CILP ADAMTS1 DDR2 TGFB3 ASXL3	6.56e-06	197	103	6	31c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCell	tumor_Lung-Fibroblasts-COL14A1+_matrix_FBs\|tumor_Lung / Location, Cell class and cell subclass	BOC CILP ADAMTS1 DDR2 SVEP1 TGFB3	6.75e-06	198	103	6	74f2c7ef702b25a5b99e56121229e678ed992524
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	BOC TTC28 ADAMTS1 DDR2 SVEP1 DST	6.95e-06	199	103	6	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MYO1E ENPP2 DDR2 SVEP1 TGFB3 LOXL2	7.15e-06	200	103	6	ad3fb8ef0be45032369d1325024787fbe1dfb8d6
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	TTC28 ADAMTS3 ADAMTS1 DDR2 SVEP1 DST	7.15e-06	200	103	6	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	normal_Lung-Fibroblasts-COL14A1+_matrix_FBs\|normal_Lung / Location, Cell class and cell subclass	BOC CILP ADAMTS1 DDR2 SVEP1 TGFB3	7.15e-06	200	103	6	ee3d06865a6300e1279edf6664320b71647f5efb
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SEMA6C RELN HTR2A RANBP6 ASB16	3.64e-05	161	103	5	b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GALNT12 GAB3 FKBPL HERC3 PSD4	4.09e-05	165	103	5	0c80abf13409767825ef8a507b498afafa7e89c5
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GALNT12 GAB3 FKBPL HERC3 PSD4	4.09e-05	165	103	5	cced77f2d74b07010307d7f4788b8cf3fdaeb91a
ToppCell	10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages\|bone_marrow / Manually curated celltypes from each tissue	TTC28 ENPP2 CEP295NL SPTBN5 DST	5.26e-05	174	103	5	0746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCell	droplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 ADAM8 EML5 ARMC6 S100PBP	5.56e-05	176	103	5	24b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Lymphocytic-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RANBP6 GALNT12 PAFAH2 HERC3 PSD4	5.56e-05	176	103	5	096cbcefd9dcbaee660568998ba210253b58501e
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Lymphocytic\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RANBP6 GALNT12 PAFAH2 HERC3 PSD4	5.56e-05	176	103	5	90198fb79e8b08e9e7df538cbc05ad7141e78517
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	BOC ADAMTS1 DDR2 SVEP1 TGFB3	5.71e-05	177	103	5	3d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAM23 ADAM8 EML5 ARMC6 S100PBP	5.71e-05	177	103	5	f360f7099570d248531897b96e0de282e58f59e9
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	STARD8 HTR2A ADAMTS3 SVEP1 GAB3	6.02e-05	179	103	5	cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RANBP6 GALNT12 PAFAH2 HERC3 PSD4	6.34e-05	181	103	5	8a8061725e718c89a4c751a415120c5312acc757
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC ADAMTS1 SVEP1 TGFB3 LOXL2	6.34e-05	181	103	5	ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3\|TCGA-Lung / Sample_Type by Project: Shred V9	ADAM23 METTL24 FRRS1L MTCL1 FAM43A	6.86e-05	184	103	5	ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	TTC28 ADAMTS3 SVEP1 ZMAT3 GNB4	6.86e-05	184	103	5	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 ENPP2 DDR2 SVEP1 LOXL2	7.04e-05	185	103	5	3cd0686a14e734a0f243070ab939adcb4c454478
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS1 ADAM23 IGF1R LOXL2 FAM43A	7.04e-05	185	103	5	742350093d90f96735dc73e3360cdd749bae63fd
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 ENPP2 DDR2 SVEP1 LOXL2	7.04e-05	185	103	5	00258f458cbf6d36449db95528a6b5038d731d2d
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 ENPP2 DDR2 SVEP1 LOXL2	7.04e-05	185	103	5	a94694e226856bc5b168464f52d76004145717a5
ToppCell	facs-Thymus-Epithelium-24m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC CILP ENPP2 DDR2 SVEP1	7.04e-05	185	103	5	eaa54b76743628c89b4310be57b87fa92b75fd37
ToppCell	facs-Thymus-Epithelium-24m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC CILP ENPP2 DDR2 SVEP1	7.04e-05	185	103	5	f7f4c921d248c637351e2e882589b99ba7f04b66
ToppCell	facs-Thymus-Epithelium-24m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC CILP ENPP2 DDR2 SVEP1	7.04e-05	185	103	5	ff38a15af3dec36d9993f06623591872b5d1da9a
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CILP ENPP2 DDR2 SVEP1 LOXL2	7.22e-05	186	103	5	a7ab70b049742dfe7ee30557031bfac6412edf52
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ENPP2 DDR2 DST LOXL2 ADAMTS14	7.22e-05	186	103	5	e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCell	Control-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	MYO1E ADAMTS3 ADAM23 ENPP2 LOXL2	7.40e-05	187	103	5	5429ae85942b8ec3895cceb63c663de3c24ca064
ToppCell	Control-Endothelial-VE_Peribronchial\|Control / Disease state, Lineage and Cell class	ADAMTS1 ADAM23 ENPP2 LOXL2 FAM43A	7.59e-05	188	103	5	f5b7dbc89f992c13280d36a34935be83906b1bc0
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	BOC ADAMTS3 ADAMTS1 DDR2 SVEP1	7.59e-05	188	103	5	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	Control-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	ADAMTS1 ADAM23 ENPP2 LOXL2 FAM43A	7.78e-05	189	103	5	c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	BOC CILP DDR2 PLCD4 APCDD1L	7.78e-05	189	103	5	eccf3d49354a67c94f1ed7c15a98a48a5e8e2ed0
ToppCell	PBMC-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	IPO5 ATP7B ABCC11 BRCA1 MOCOS	7.78e-05	189	103	5	946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	BOC CILP DDR2 PLCD4 APCDD1L	7.78e-05	189	103	5	40764f461b8aa1d3a2c5a30590b7fb9307d47d09
ToppCell	(2)_Fibroblasts-(22)_Fibro-3\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	RELN CILP ADAM23 ENPP2 TGFB3	7.98e-05	190	103	5	3aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DDR2 SVEP1 DST METTL24 EML5	8.18e-05	191	103	5	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DDR2 SVEP1 DST METTL24 EML5	8.18e-05	191	103	5	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CILP DDR2 PLCD4 LOXL2 APCDD1L	8.18e-05	191	103	5	44b1f62fdee03b157fe545f2ae6ff84f8929a8ac
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CILP ENPP2 DDR2 SVEP1 LOXL2	8.38e-05	192	103	5	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC DDR2 SVEP1 TGFB3 LOXL2	8.38e-05	192	103	5	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BOC ADAMTS1 ENPP2 LOXL2 ADAMTS14	8.38e-05	192	103	5	93903576dddd8227328e4ced75aa7625eedb9baf
ToppCell	facs-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC DDR2 SVEP1 TGFB3 LOXL2	8.38e-05	192	103	5	eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-SVEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYO1E ADAMTS1 ADAM23 ENPP2 LOXL2	8.38e-05	192	103	5	c3dda7c48732b0b8bde36de282d64192f5e9b98f
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BOC CILP DDR2 SVEP1 TGFB3	8.38e-05	192	103	5	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CILP ENPP2 DDR2 SVEP1 LOXL2	8.38e-05	192	103	5	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CILP ENPP2 DDR2 SVEP1 LOXL2	8.38e-05	192	103	5	136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CILP ADAMTS3 DDR2 SVEP1 ASXL3	8.59e-05	193	103	5	59b8186d0221fba06a16157e9d148399ed801f38
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC ADAMTS1 DDR2 SVEP1 LOXL2	8.59e-05	193	103	5	f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAD TTC28 ENPP2 DST EML5	8.59e-05	193	103	5	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BOC ADAMTS1 ENPP2 LOXL2 ADAMTS14	8.59e-05	193	103	5	cfab88935abe0a15632c5eec8ff00a857ec9b3ed
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC DDR2 SVEP1 TGFB3 LOXL2	8.59e-05	193	103	5	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CILP ADAMTS3 DDR2 SVEP1 ASXL3	8.59e-05	193	103	5	dc92680b4bb9fc26430c92e03adb839c8c3b3b98
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ADAM23 DDR2 ODAD2 GNB1	8.59e-05	193	103	5	2483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAD TTC28 ENPP2 DST EML5	8.59e-05	193	103	5	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	BOC CILP TGFB3 ASXL3 LOXL2	8.59e-05	193	103	5	09de51f8ac509e03d480ed3dc9dfe7e7defc59cb
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CILP ADAMTS3 DDR2 SVEP1 ASXL3	8.59e-05	193	103	5	03678162648bd5b1d65a5450b60c8863edbf95c7
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	BOC STARD8 CILP ADAM23 TGFB3	8.59e-05	193	103	5	194e7fa00a50cc4e026987b715323d125d79594e
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC ADAMTS1 DDR2 SVEP1 LOXL2	8.59e-05	193	103	5	85faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BOC ADAMTS1 DDR2 SVEP1 LOXL2	8.59e-05	193	103	5	25248b8e65d558b1a96a87c93e3e5b4c0ba168fe
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BOC ADAMTS1 DDR2 SVEP1 LOXL2	8.59e-05	193	103	5	f1f1097204e07a7bed416425b8256942038a734f
ToppCell	facs-MAT-Fat-3m-Mesenchymal\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC ADAMTS1 DDR2 SVEP1 LOXL2	8.59e-05	193	103	5	110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BOC CILP DDR2 TGFB3 LOXL2	8.80e-05	194	103	5	5594f7437448cb4b37d2d100f44d30c4a367df26
ToppCell	droplet-Pancreas-Endocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAD TTC28 ENPP2 DST EML5	8.80e-05	194	103	5	3a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADAMTS1 ENPP2 EHMT1 PLXNB1 SP140	8.80e-05	194	103	5	3211d89440a6f4a9b3d4cfb755890816944242ec
ToppCell	COPD-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	MYO1E ADAMTS3 ADAMTS1 ADAM23 VDAC1	8.80e-05	194	103	5	8dcde77767b23e75360adb316cdccf56a00e3726
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma\|TCGA-Adrenal / Sample_Type by Project: Shred V9	PLCD4 IGFBPL1 DGKK MTCL1 CTNND2	8.80e-05	194	103	5	b6488bc3a8905e926ad298332963e1bbaf010046
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma\|TCGA-Adrenal / Sample_Type by Project: Shred V9	PLCD4 IGFBPL1 DGKK MTCL1 CTNND2	8.80e-05	194	103	5	1e1f4139ad584f493d75a9b7f1568eca4653c5a2
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAD TTC28 ENPP2 DST EML5	8.80e-05	194	103	5	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BOC CILP DDR2 SVEP1 DST	9.01e-05	195	103	5	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS1 ADAM23 ENPP2 DDR2 LOXL2	9.01e-05	195	103	5	223f5f07dc28fa13a09bb589884c58043c7928c7
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BOC ADAMTS1 DDR2 SVEP1 TGFB3	9.01e-05	195	103	5	773728703bc8969bff0e1de58fe3e1631add0a0a
ToppCell	facs-Bladder-nan-18m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAM23 ENPP2 DDR2 SVEP1 LOXL2	9.01e-05	195	103	5	3e4f9ecfaa756386d816a26313b7229ec092d4e6
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BOC DDR2 SVEP1 TGFB3 LOXL2	9.01e-05	195	103	5	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENPP2 SCRN2 IGF1R DST VDAC1	9.23e-05	196	103	5	d74e899cc120146dded3a20716e22c7aca4f074a
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 DDR2 SVEP1 TGFB3 DST	9.23e-05	196	103	5	9737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell	Bronchial-NucSeq-Stromal-Schwann\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RELN HTR2A MYO1E ADAM23 SHC4	9.23e-05	196	103	5	a90c76d9c57a4491b94a321ba541b792ec5d8e83
ToppCell	mLN-T_cell-gd_T\|T_cell / Region, Cell class and subclass	MYO1E METTL24 ASB16 FKBPL PLXNB1	9.23e-05	196	103	5	8f476408cd5a4ea9d25c763c66565343d7989b38
ToppCell	droplet-Bladder-nan-3m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS1 ADAM23 ENPP2 DDR2 LOXL2	9.23e-05	196	103	5	f47e551ba484687ba6ce8c29a085106131364042
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 DDR2 SVEP1 TGFB3 DST	9.23e-05	196	103	5	cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAMTS1 DDR2 SVEP1 TGFB3 DST	9.46e-05	197	103	5	94a9603cbd3516fbcce871909693b88f20d41713
Disease	osteoarthritis (is_implicated_in)	CILP DDR2 ADAMTS14	1.16e-04	28	100	3	DOID:8398 (is_implicated_in)
Disease	autism spectrum disorder (implicated_via_orthology)	HTR2A TSC1 ELP2 CTNND2 MOCOS	1.72e-04	152	100	5	DOID:0060041 (implicated_via_orthology)
Disease	Unipolar Depression	RELN HTR2A ATP7B DIXDC1 CTNND2 GNB1	2.58e-04	259	100	6	C0041696
Disease	vital capacity	MYO1E ADAMTS3 ADAMTS1 ENPP2 POLR2B HKDC1 ODAD2 SVEP1 IGF1R DST GAB3 MTCL1 GNB1	2.77e-04	1236	100	13	EFO_0004312
Disease	7-methylguanine measurement	ELP2 MOCOS	3.14e-04	8	100	2	EFO_0021123
Disease	Acute Confusional Senile Dementia	RELN ADAMTS1 ABCA7 IGF1R	3.65e-04	99	100	4	C0546126
Disease	Alzheimer's Disease, Focal Onset	RELN ADAMTS1 ABCA7 IGF1R	3.65e-04	99	100	4	C0750900
Disease	Alzheimer Disease, Early Onset	RELN ADAMTS1 ABCA7 IGF1R	3.65e-04	99	100	4	C0750901
Disease	Presenile dementia	RELN ADAMTS1 ABCA7 IGF1R	3.65e-04	99	100	4	C0011265
Disease	Alzheimer Disease, Late Onset	RELN ADAMTS1 ABCA7 IGF1R	3.65e-04	99	100	4	C0494463
Disease	Melancholia	RELN DIXDC1 GNB1	3.67e-04	41	100	3	C0025193
Disease	Depression, Neurotic	RELN DIXDC1 GNB1	3.67e-04	41	100	3	C0282126
Disease	Familial Alzheimer Disease (FAD)	RELN ADAMTS1 ABCA7 IGF1R	3.79e-04	100	100	4	C0276496
Disease	Depressive Syndrome	RELN DIXDC1 GNB1	3.94e-04	42	100	3	C0086133
Disease	Alzheimer's Disease	RELN ADAMTS1 ABCA7 IGF1R	3.94e-04	101	100	4	C0002395
Disease	Endogenous depression	RELN DIXDC1 GNB1	5.16e-04	46	100	3	C0011573
Disease	colorectal cancer (is_implicated_in)	DDR2 GALNT12 BRCA1 CTNNBL1	7.79e-04	121	100	4	DOID:9256 (is_implicated_in)
Disease	neurofilament light chain measurement	NAT1 ADAMTS1 SMCR8	9.68e-04	57	100	3	EFO_0009178
Disease	renal cell carcinoma (biomarker_via_orthology)	CAD IGF1R	1.01e-03	14	100	2	DOID:4450 (biomarker_via_orthology)
Disease	Malignant neoplasm of breast	BOC STARD8 ATP7B ADAMTS1 ZNF668 IGF1R BRCA1 LOXL2 EHMT1 FKBPL PLXNB1	1.04e-03	1074	100	11	C0006142
Disease	Hepatitis	ATP7B ENPP2	1.16e-03	15	100	2	C0019158
Disease	Neoplastic Cell Transformation	IGF1R BRCA1 LOXL2 CTNND2	1.30e-03	139	100	4	C0007621
Disease	Lewy body measurement, Parkinson disease	HTR2A ZP3	1.32e-03	16	100	2	EFO_0007021, MONDO_0005180
Disease	Inherited oocyte maturation defect	ZP3 WEE2	1.32e-03	16	100	2	cv:CN238505
Disease	hyperglycemia (implicated_via_orthology)	HTR2A HKDC1	1.50e-03	17	100	2	DOID:4195 (implicated_via_orthology)
Disease	major depressive disorder (is_implicated_in)	HTR2A CTNND2	1.50e-03	17	100	2	DOID:1470 (is_implicated_in)
Disease	Manic Disorder	RELN HTR2A DIXDC1	1.83e-03	71	100	3	C0024713
Disease	Fetal Growth Retardation	IGF1R CTH	2.08e-03	20	100	2	C0015934
Disease	Mammary Carcinoma, Human	STARD8 ATP7B ADAMTS1 IGF1R BRCA1 LOXL2 FKBPL	2.09e-03	525	100	7	C4704874
Disease	Mammary Neoplasms, Human	STARD8 ATP7B ADAMTS1 IGF1R BRCA1 LOXL2 FKBPL	2.09e-03	525	100	7	C1257931
Disease	Mammary Neoplasms	STARD8 ATP7B ADAMTS1 IGF1R BRCA1 LOXL2 FKBPL	2.14e-03	527	100	7	C1458155
Disease	Manic	RELN HTR2A DIXDC1	2.39e-03	78	100	3	C0338831
Disease	Breast Carcinoma	STARD8 ATP7B ADAMTS1 IGF1R BRCA1 LOXL2 FKBPL	2.40e-03	538	100	7	C0678222
Disease	Depression, Bipolar	RELN HTR2A DIXDC1	2.48e-03	79	100	3	C0005587
Disease	Colorectal Neoplasms	BOC STARD8 ATP7B GALNT12 GNB4	2.56e-03	277	100	5	C0009404
Disease	Colorectal Carcinoma	BOC CAD STARD8 ATP7B GALNT12 ATAD1 GNB4 CTNND2	2.69e-03	702	100	8	C0009402
Disease	sphingomyelin 24:1 measurement	IGF1R CCDC70	2.75e-03	23	100	2	EFO_0010398
Disease	Epilepsy, Cryptogenic	TSC1 ASXL3 VDAC1	2.76e-03	82	100	3	C0086237
Disease	Awakening Epilepsy	TSC1 ASXL3 VDAC1	2.76e-03	82	100	3	C0751111
Disease	Aura	TSC1 ASXL3 VDAC1	2.76e-03	82	100	3	C0236018
Disease	Hepatic Form of Wilson Disease	ATP7B LOXL2	2.99e-03	24	100	2	C1527352
Disease	Hepatolenticular Degeneration	ATP7B LOXL2	2.99e-03	24	100	2	C0019202
Disease	Depressive disorder	RELN HTR2A BRCA1 DIXDC1 GNB1	3.07e-03	289	100	5	C0011581
Disease	Schizophrenia	IPO5 RELN HTR2A ADAMTS3 EML5 BRCA1 HPGDS DIXDC1 CTNND2	3.10e-03	883	100	9	C0036341
Disease	late-onset Alzheimers disease	ADAMTS1 CEP295NL ABCA7 USP32 CTNND2	3.21e-03	292	100	5	EFO_1001870
Disease	Involutional paraphrenia	RELN HTR2A	3.24e-03	25	100	2	C1571983
Disease	Psychosis, Involutional	RELN HTR2A	3.24e-03	25	100	2	C1571984
Disease	Involutional Depression	RELN HTR2A	3.24e-03	25	100	2	C0011574

Protein segments in the cluster

Peptide	Gene	Start	Entry
EHINLGCDMDFDIAG	VDAC1	121	P21796
QRPGEGHAFSEMQEC	CEP295NL	371	Q96MC4
NIHCGDAMDLGLEAI	NAT1	41	P18440
ALSTCNGLHGMFEDD	ADAM23	211	O75077
MGHCVNLTDGAVEAV	AMN1	201	Q8IY45
VLDHAMIGPEGTDNC	CTNNBL1	356	Q8WYA6
QVCHQIGDMGFEASI	ATP7B	111	P35670
LADCNDHQMRDQSGV	ARMC6	326	Q6NXE6
AQGAAAALADVCHDM	DIXDC1	156	Q155Q3
NDCSMVALGKQHSEE	HTR2A	441	P28223
AQGDCLEALGLTMHE	APCDD1L	181	Q8NCL9
AGHTPMDCALQAVQD	ASB16	316	Q96NS5
GHSDVVMGLVSVNCE	CTH	216	P32929
VHNGIEYGDMQLICE	PGD	186	P52209
ENNGHIAGEQMLEDG	CCDC70	201	Q6NSX1
DDPSLEGMCGTEHAQ	RAD54L2	46	Q9Y4B4
GMDHDENVQGCRCQE	ADAM8	341	P78325
QGQHMGTDELDGLLC	CTNND2	781	Q9UQB3
DMAEANAHGEENGVC	ASXL3	106	Q9C0F0
MEHDGQGNGCADETS	ADAMTS14	406	Q8WXS8
AADTDMEDGSCGQHL	ABCA7	1151	Q8IZY2
ITSFLDNGHGECLMD	ADAMTS1	451	Q9UHI8
GGQTCFSLEMEEEHL	MTCL1	981	Q9Y4B5
AGQHGRALMEACNEF	PARP2	291	Q9UGN5
AQCHEVMITIDGEEG	DGKK	991	Q5KSL6
EGQFGEVHLCEVEGM	DDR2	571	Q16832
MLLEGCHAEFDGNTA	DST	2021	Q03001
CNLGHLEDGADSMES	GAB3	116	Q8WWW8
CGQLGHDSMNDEVNP	HERC3	271	Q15034
DLAGNTEMEQCHVDA	HPGDS	76	O60760
HEEDAGVRCNTPAMG	LOXL2	416	Q9Y4K0
SDSEGFVIHDGECMQ	IGF1R	291	P08069
EMLVAGHEDSNGCIN	MYL6	126	P60660
HLFQDGPGDNECVME	PLXNB1	941	O43157
ENGKICENGTHSELM	ABCC11	706	Q96J66
EDEGVYQCHAANMVG	IGFBPL1	236	Q8WX77
HEEEMKALQCAAGGN	KRT27	226	Q7Z3Y8
HDNRVSCLGVTDDGM	GNB2	311	P62879
HDNRVSCLGVTDDGM	GNB4	311	Q9HAV0
AGHVCGDNMDLIDGQ	MOCOS	446	Q96EN8
ALSAIGEGCHQQMEG	IPO5	381	O00410
GEGCHQQMEGILNEI	IPO5	386	O00410
ETGEQCGAIMHGNAV	RELN	226	P78509
TEDNGFHAIGQMCEA	BRCA1	1816	P38398
MEHDGQGNRCGDETA	ADAMTS3	406	O15072
VCHMGVCQGQGDTED	CEMP1	226	Q6PRD7
SMCQGEEAELQLPGH	FKBPL	166	Q9UIM3
GAADIAASQHVMVCA	HEATR5B	406	Q9P2D3
GEFVGGCDILLQMHQ	GLRX5	116	Q86SX6
CMAENEVGSAHAVVQ	BOC	391	Q9BWV1
HDNRVSCLGVTDDGM	GNB1	311	P62873
GDDVMACVHDDNGRV	FRRS1L	156	Q9P0K9
GDTCSFAQMDVRQHG	ATG9A	516	Q7Z3C6
AGKIEFENELNHMCG	C3orf62	191	Q6ZUJ4
SGHICSQMFEGQILD	CRYBG2	1616	Q8N1P7
NDANCIHMVDNGIVE	RAP1GDS1	346	P52306
HQPEGCIAVEAGMDT	GALNT12	501	Q8IXK2
MHFECGDLLDTLENG	FAM43A	306	Q8N2R8
CAAVNADGIHLALGM	EML5	371	Q05BV3
DCQFNEDGSMIIAHA	ELP2	346	Q6IA86
QGISGELCALMDQVH	S100PBP	341	Q96BU1
AHMAADGETNGSCEN	EHMT1	46	Q9H9B1
CVNVIFVGDHGMEDV	ENPP2	351	Q13822
HLVGCGDVMEGQNLQ	PAFAH2	16	Q99487
DTHFEVSMANNGCEV	METTL24	191	Q5JXM2
DLGSMNQACIHVEGS	STK16	166	O75716
TAGLEMDICDGHFRQ	PLCD4	581	Q9BRC7
MDSLQDTVALDHGGC	SLC47A2	1	Q86VL8
FLHSADGEGCANMLV	GET4	166	Q7L5D6
MQGTGEELFDHIVQC	HKDC1	566	Q2TB90
MGANEHGVCIGNEAV	SCRN2	86	Q96FV2
MGANEHGVCIGNEAV	SCRN3	81	Q0VDG4
SEDADNCITMHENGA	ODAD2	991	Q5T2S8
GEDHCLEGESLVGQM	PSD4	821	Q8NDX1
FGEMERDCQIAHGAA	POLR2B	1086	P30876
NKEHDEACLAGVAQM	WDR19	806	Q8NEZ3
FQVAGHAMQTCEESG	SVEP1	2586	Q4LDE5
SAIGEGCHQQMESIL	RANBP6	391	O60518
CQAEALSQMEVPAHG	STARD8	356	Q92502
MGANEHGVCIANEAI	SCRN1	81	Q12765
VKMNVGDLGQDLEHC	SPTBN5	2276	Q9NRC6
LCPGEMEHIQDQASQ	SMCR8	266	Q8TEV9
DGLDTDHSCQVIVMG	ATAD1	221	Q8NBU5
LNDHVGEQDMGECDV	CDYL2	181	Q8N8U2
GEQDMGECDVNHATL	CDYL2	186	Q8N8U2
SEASEEGQHCMGQDC	CILP	186	O75339
ECHNGMAQDVISTIG	SHC4	321	Q6S5L8
ICSDEHMQGSGSLAQ	RNF213	3896	Q63HN8
CNDGCSDSMVGHNEE	TSC1	996	Q92574
VVGMTVEHVECQDAG	ZNF668	476	Q96K58
CHGMENEAIASEQSV	ZNF551	71	Q7Z340
DSGAENEGSCHSDQM	USP47	436	Q96K76
LQARMSCEQKAEGHG	RAET1G	121	Q6H3X3
VDQAGNQESMEHGDC	SEMA6C	556	Q9H3T2
NQESMEHGDCQDGAT	SEMA6C	561	Q9H3T2
LQEEGSGVMHQECQI	nan	81	Q1RN00
CNMENLDPLGIHTGE	CAD	616	P27708
AHMNVDIACAVADGE	YY1AP1	681	Q9H869
NQGVCAHQDSEDKGM	ZNF697	6	Q5TEC3
DLQDMEGEGKVCHNL	TTC28	626	Q96AY4
CNVGAGEEMEFRQHL	ZMAT3	251	Q9HA38
GKQENSNACHEMDDI	SP140	161	Q13342
EDDHMIIQNEYCNGG	WEE2	281	P0C1S8
RFEVGLHECGNSMQV	ZP3	91	P21754
EEMHGEREEGCTQEN	TGFB3	81	P10600
QEASNHAQDCDDSMG	USP32	1136	Q8NFA0
VCATMHAVGEGADQT	MYO1E	466	Q12965