Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

MYT1L ZNF771 KLF12 ZNF211 ZSCAN10 ZBTB17 CSRNP2 EGR4 ZNF425 BHLHE22 ZNF184 ZNF213 ZNF224 IRX6 IRX2 THAP1 CREBZF TBX2

1.58e-0514128318GO:0000981
GeneOntologyMolecularFunctionsignaling receptor inhibitor activity

WFIKKN1 WFIKKN2 FST PCSK9

3.96e-0546834GO:0030547
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

MYT1L KLF12 ZBTB17 ZNF224 IRX6 IRX2 THAP1 TBX2

5.54e-05320838GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

MYT1L KLF12 ZBTB17 ZNF224 IRX6 IRX2 THAP1 TBX2

6.31e-05326838GO:0001217
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

MYT1L ZNF771 KLF12 ZNF211 ZSCAN10 ZBTB17 EGR4 ZNF425 RBL1 BHLHE22 ZNF184 ZNF213 ZNF224 IRX6 IRX2 THAP1 TBX2

8.77e-0514598317GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

MYT1L ZNF771 KLF12 ZNF211 ZSCAN10 ZBTB17 EGR4 BHLHE22 ZNF184 ZNF213 ZNF224 IRX6 IRX2 THAP1 TBX2

1.68e-0412448315GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

MYT1L ZNF771 KLF12 ZNF211 ZSCAN10 ZBTB17 EGR4 BHLHE22 ZNF184 ZNF213 ZNF224 IRX6 IRX2 THAP1 TBX2

2.12e-0412718315GO:0000987
GeneOntologyMolecularFunctionreceptor antagonist activity

WFIKKN1 WFIKKN2 FST

3.15e-0432833GO:0048019
GeneOntologyMolecularFunctiongrowth factor binding

WFIKKN1 DUSP1 WFIKKN2 LRP2 LTBP2

4.85e-04156835GO:0019838
GeneOntologyMolecularFunctionmolecular function inhibitor activity

SERPINB6 SPP2 WFIKKN1 WFIKKN2 SPRED1 HSPBP1 FST TRIB1 PCSK9

8.16e-04596839GO:0140678
MousePhenodecreased quadriceps weight

WFIKKN1 WFIKKN2 FST

1.85e-0511693MP:0010227
DomainGrowth_fac_rcpt_

EPHB3 ATRN ELAPOR2 DLL4 DNER LRP2 LRP4 LTBP2

4.18e-07156828IPR009030
DomainEGF_extracell

ATRN DLL4 DNER LRP2 LTBP2

6.52e-0660825IPR013111
DomainEGF_2

ATRN DLL4 DNER LRP2 LTBP2

6.52e-0660825PF07974
DomainEGF

ATRN DLL4 DNER LRP2 LRP4 LTBP2

1.93e-05126826PF00008
DomainKAZAL_1

WFIKKN1 WFIKKN2 FST

6.35e-0518823PS00282
DomainASX_HYDROXYL

DLL4 DNER LRP2 LRP4 LTBP2

7.83e-05100825PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

DLL4 DNER LRP2 LRP4 LTBP2

1.03e-04106825IPR000152
DomainEphrin_rec_like

EPHB3 ELAPOR2 TNFRSF11B

1.75e-0425823SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

EPHB3 ELAPOR2 TNFRSF11B

1.75e-0425823IPR011641
Domain-

ZNF771 KLF12 ZNF211 ZSCAN10 ZBTB17 EGR4 ZNF425 ZNF184 ZNF213 ZNF224 REPIN1

1.81e-0467982113.30.160.60
DomainEGF_CA

DLL4 DNER LRP2 LRP4 LTBP2

2.00e-04122825SM00179
DomainEGF-like_Ca-bd_dom

DLL4 DNER LRP2 LRP4 LTBP2

2.16e-04124825IPR001881
Domainzf-C2H2

ZNF771 KLF12 ZNF211 ZSCAN10 ZBTB17 EGR4 ZNF425 ZNF184 ZNF213 ZNF224 REPIN1

2.16e-046938211PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF771 KLF12 ZNF211 ZSCAN10 ZBTB17 EGR4 ZNF425 ZNF184 ZNF213 ZNF224 REPIN1

2.19e-046948211IPR013087
DomainIRO

IRX6 IRX2

2.82e-046822SM00548
DomainIroquois_homeo

IRX6 IRX2

2.82e-046822IPR003893
DomainKazal_2

WFIKKN1 WFIKKN2 FST

5.25e-0436823PF07648
DomainZINC_FINGER_C2H2_2

ZNF771 KLF12 ZNF211 ZSCAN10 ZBTB17 EGR4 ZNF425 ZNF184 ZNF213 ZNF224 REPIN1

5.58e-047758211PS50157
DomainZINC_FINGER_C2H2_1

ZNF771 KLF12 ZNF211 ZSCAN10 ZBTB17 EGR4 ZNF425 ZNF184 ZNF213 ZNF224 REPIN1

5.70e-047778211PS00028
DomainEGF_3

ATRN DLL4 DNER LRP2 LRP4 LTBP2

5.87e-04235826PS50026
DomainEGF

ATRN DLL4 DNER LRP2 LRP4 LTBP2

5.87e-04235826SM00181
DomainTB

LTBP2 FST

6.72e-049822PS51364
DomainTB_dom

LTBP2 FST

6.72e-049822IPR017878
DomainZnf_C2H2-like

ZNF771 KLF12 ZNF211 ZSCAN10 ZBTB17 EGR4 ZNF425 ZNF184 ZNF213 ZNF224 REPIN1

6.96e-047968211IPR015880
DomainZnf_C2H2

ZNF771 KLF12 ZNF211 ZSCAN10 ZBTB17 EGR4 ZNF425 ZNF184 ZNF213 ZNF224 REPIN1

7.63e-048058211IPR007087
DomainZnF_C2H2

ZNF771 KLF12 ZNF211 ZSCAN10 ZBTB17 EGR4 ZNF425 ZNF184 ZNF213 ZNF224 REPIN1

7.87e-048088211SM00355
DomainEGF-like_dom

ATRN DLL4 DNER LRP2 LRP4 LTBP2

7.95e-04249826IPR000742
DomainEGF_Ca-bd_CS

DNER LRP2 LRP4 LTBP2

8.77e-0497824IPR018097
DomainEGF_1

ATRN DLL4 DNER LRP2 LRP4 LTBP2

8.99e-04255826PS00022
DomainEGF_CA

DNER LRP2 LRP4 LTBP2

9.47e-0499824PS01187
DomainLdl_recept_a

TMPRSS9 LRP2 LRP4

1.01e-0345823PF00057
DomainEGF-like_CS

ATRN DLL4 DNER LRP2 LRP4 LTBP2

1.01e-03261826IPR013032
DomainFol_N

DNER FST

1.02e-0311822IPR003645
DomainFOLN

DNER FST

1.02e-0311822SM00274
DomainKAZAL

WFIKKN1 WFIKKN2 FST

1.08e-0346823SM00280
Domain-

TMPRSS9 LRP2 LRP4

1.08e-03468234.10.400.10
DomainEGF_2

ATRN DLL4 DNER LRP2 LRP4 LTBP2

1.10e-03265826PS01186
DomainARM-like

SCYL2 PLAA TOGARAM2 HSPBP1 PPP6R2 NCAPG2

1.21e-03270826IPR011989
DomainLDLRA_1

TMPRSS9 LRP2 LRP4

1.22e-0348823PS01209
DomainLDLRA_2

TMPRSS9 LRP2 LRP4

1.30e-0349823PS50068
DomainLDrepeatLR_classA_rpt

TMPRSS9 LRP2 LRP4

1.30e-0349823IPR002172
DomainLDLa

TMPRSS9 LRP2 LRP4

1.30e-0349823SM00192
DomainKAZAL_2

WFIKKN1 WFIKKN2 FST

1.38e-0350823PS51465
DomainKazal_dom

WFIKKN1 WFIKKN2 FST

1.46e-0351823IPR002350
DomainLdl_recept_b

LRP2 LRP4

1.67e-0314822PF00058
DomainLDLRB

LRP2 LRP4

1.67e-0314822PS51120
DomainLY

LRP2 LRP4

1.93e-0315822SM00135
DomainLDLR_classB_rpt

LRP2 LRP4

1.93e-0315822IPR000033
DomainWAP

WFIKKN1 WFIKKN2

2.20e-0316822SM00217
DomainWAP

WFIKKN1 WFIKKN2

2.20e-0316822PF00095
DomainHomeobox_KN

IRX6 IRX2

2.48e-0317822PF05920
DomainHomeobox_KN_domain

IRX6 IRX2

2.48e-0317822IPR008422
DomainWAP

WFIKKN1 WFIKKN2

2.48e-0317822PS51390
Domain-

WFIKKN1 WFIKKN2

2.48e-03178224.10.75.10
Domainzf-C2H2_6

ZNF771 ZNF211 ZSCAN10 ZNF425 ZNF184 ZNF224

2.58e-03314826PF13912
Domain-

WFIKKN1 WFIKKN2

2.78e-03188224.10.410.10
DomainPrtase_inh_Kunz-CS

WFIKKN1 WFIKKN2

2.78e-0318822IPR020901
DomainKU

WFIKKN1 WFIKKN2

2.78e-0318822SM00131
DomainNTR

WFIKKN1 WFIKKN2

3.10e-0319822PF01759
DomainBPTI_KUNITZ_2

WFIKKN1 WFIKKN2

3.10e-0319822PS50279
DomainKunitz_BPTI

WFIKKN1 WFIKKN2

3.10e-0319822PF00014
DomainNetrin_module_non-TIMP

WFIKKN1 WFIKKN2

3.10e-0319822IPR018933
DomainBPTI_KUNITZ_1

WFIKKN1 WFIKKN2

3.10e-0319822PS00280
DomainARM-type_fold

SCYL2 PLAA TOGARAM2 HSPBP1 PPP6R2 NCAPG2

3.77e-03339826IPR016024
DomainWAP_dom

WFIKKN1 WFIKKN2

4.15e-0322822IPR008197
DomainTNFR_c6

TNFRSF10A TNFRSF11B

4.15e-0322822PF00020
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

MYT1L KLF12 KLHL5 ZSCAN10 PLAA TEX2 INPP5E GLYR1 LRP2 SPRED1 PEAK1 REPIN1 SLX4

1.97e-061084841311544199
Pubmed

HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2.

SPP2 LRP2 IRX2 PCSK9

2.71e-064084423362348
Pubmed

Distinct expression pattern of two related human proteins containing multiple types of protease-inhibitory modules.

WFIKKN1 WFIKKN2

5.76e-06284211928817
Pubmed

Expression, purification and characterization of the second Kunitz-type protease inhibitor domain of the human WFIKKN protein.

WFIKKN1 WFIKKN2

5.76e-06284212709070
Pubmed

Follistatin binds to both activin and inhibin through the common subunit.

INHA FST

5.76e-0628422036994
Pubmed

Proprotein convertase subtilisin/kexin type 9 targets megalin in the kidney proximal tubule and aggravates proteinuria in nephrotic syndrome.

LRP2 PCSK9

5.76e-06284237406929
Pubmed

Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2.

WFIKKN1 WFIKKN2 FST

6.06e-061584324019467
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

MYT1L SCYL2 ATRN NISCH DNER APBB2 LRP2 LRP4 SPRED1 ZNF224 SLX4 CREBZF MPRIP

1.23e-051285841335914814
Pubmed

Testicular activin and follistatin levels are elevated during the course of experimental autoimmune epididymo-orchitis in mice.

INHA FST

1.73e-05384228205525
Pubmed

Associations for BCO2, PCSK9, and TR1B1 Polymorphism and Lifestyle Factors with Ischemic Stroke: A Nested Case-Control Study.

TRIB1 PCSK9

1.73e-05384231250580
Pubmed

Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity.

EPHB3 GRIN1

1.73e-05384211754835
Pubmed

The Activin Social Network: Activin, Inhibin, and Follistatin in Breast Development and Cancer.

INHA FST

1.73e-05384230874767
Pubmed

Molecular cloning and mapping of a novel developmentally regulated human C2H2-type zinc finger.

ZNF211 INHA

1.73e-0538429096115
Pubmed

WFIKKN1 and WFIKKN2: "Companion" proteins regulating TGFB activity.

WFIKKN1 WFIKKN2

1.73e-05384227325460
Pubmed

The Liver Clock Controls Cholesterol Homeostasis through Trib1 Protein-mediated Regulation of PCSK9/Low Density Lipoprotein Receptor (LDLR) Axis.

TRIB1 PCSK9

3.45e-05484226547624
Pubmed

Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11.

WFIKKN1 WFIKKN2

3.45e-05484218596030
Pubmed

Association between endometriosis and polymorphisms in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), TRAIL receptor and osteoprotegerin genes and their serum levels.

TNFRSF10A TNFRSF11B

3.45e-05484222392486
Pubmed

Cloning and chromosome mapping of human and chicken Iroquois (IRX) genes.

IRX6 IRX2

3.45e-05484211435706
Pubmed

Notch signaling regulates ovarian follicle formation and coordinates follicular growth.

DLL4 INHA FST

5.26e-053084324552588
Pubmed

Differential expression of inhibin subunits and follistatin, but not of activin receptor type II, during early murine embryonic development.

INHA FST

5.74e-0558421330789
Pubmed

Hormone therapy and maximal eccentric exercise alters myostatin-related gene expression in postmenopausal women.

WFIKKN2 FST

5.74e-05584222395277
Pubmed

Differential binding and neutralization of activins A and B by follistatin and follistatin like-3 (FSTL-3/FSRP/FLRG).

INHA FST

5.74e-05584212697670
Pubmed

Expression of inhibin subunits and follistatin during postimplantation mouse development: decidual expression of activin and expression of follistatin in primitive streak, somites and hindbrain.

INHA FST

5.74e-0558427600958
Pubmed

Following a TRAIL: update on a ligand and its five receptors.

TNFRSF10A TNFRSF11B

5.74e-05584215538968
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP2 LRP4

5.74e-05584219047013
Pubmed

Inhibin α-subunit N terminus interacts with activin type IB receptor to disrupt activin signaling.

INHA FST

5.74e-05584222267736
Pubmed

IL-7R-dependent survival and differentiation of early T-lineage progenitors is regulated by the BTB/POZ domain transcription factor Miz-1.

ZBTB17 IL7R

8.59e-05684221258009
Pubmed

Latent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2.

WFIKKN1 WFIKKN2

8.59e-05684223829672
Pubmed

Comparison of Iroquois gene expression in limbs/fins of vertebrate embryos.

IRX6 IRX2

8.59e-05684220408909
Pubmed

Expression of activin subunits, activin receptors and follistatin in postimplantation mouse embryos suggests specific developmental functions for different activins.

INHA FST

8.59e-0568427821227
Pubmed

Iroquois homeobox 3 regulates odontoblast proliferation and differentiation mediated by Wnt5a expression.

IRX6 IRX2

8.59e-05684236773339
Pubmed

Organization of mouse Iroquois homeobox genes in two clusters suggests a conserved regulation and function in vertebrate development.

IRX6 IRX2

8.59e-05684211042145
Pubmed

Activin disrupts epithelial branching morphogenesis in developing glandular organs of the mouse.

INHA FST

8.59e-0568427619733
Pubmed

Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast.

IRX6 IRX2

8.59e-05684210370142
Pubmed

The prepattern transcription factor Irx3 directs nephron segment identity.

IRX6 IRX2

1.20e-04784217875669
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ATRN B3GLCT GLYR1 DNER LRP4 LTBP2 HSPBP1 PPP6R2 NCAPG2 PCSK9 GGT7

1.47e-041201841135696571
Pubmed

A transcriptional Map of the FMF region.

ZSCAN10 ZNF213

1.60e-0488429653642
Pubmed

Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior.

GRIN1 PRKG2

1.60e-04884218606955
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

MYT1L ELAPOR2 FRRS1 ZSCAN10 DUSP1 GLO1 WFIKKN2 ZNF184 GRIN1 REPIN1 SLX4

1.97e-041242841130973865
Pubmed

The Iroquois homeobox gene Irx2 is not essential for normal development of the heart and midbrain-hindbrain boundary in mice.

IRX6 IRX2

2.05e-04984214585979
Pubmed

GASP-2 overexpressing mice exhibit a hypermuscular phenotype with contrasting molecular effects compared to GASP-1 transgenics.

WFIKKN1 WFIKKN2

2.05e-04984231960486
Pubmed

The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance.

INHA FST

2.05e-04984214736745
Pubmed

Sensory inputs control the integration of neurogliaform interneurons into cortical circuits.

BHLHE22 GRIN1

2.05e-04984225664912
Pubmed

WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity.

WFIKKN1 WFIKKN2

2.05e-04984221054789
Pubmed

Gene and cluster-specific expression of the Iroquois family members during mouse development.

IRX6 IRX2

2.05e-04984211520674
Pubmed

Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia.

INHA FST

2.56e-041084212651901
Pubmed

An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.

SPP2 TNFRSF11B

2.56e-041084220548944
Pubmed

Analysis of recently identified osteoporosis susceptibility genes in Han Chinese women.

LRP4 TNFRSF11B

2.56e-041084220554715
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP2 LRP4

3.13e-041184224639464
Pubmed

High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.

RBL1 LTBP2 TNFRSF10A FST TNFRSF11B TBX2

3.38e-0438384619453261
Pubmed

A census of human transcription factors: function, expression and evolution.

MYT1L KLF12 ZBTB17 BHLHE22 IRX6 IRX2 THAP1 CREBZF TBX2

3.47e-0490884919274049
Pubmed

Brn3a-expressing retinal ganglion cells project specifically to thalamocortical and collicular visual pathways.

EPHB3 IRX2

3.75e-041284216354917
Pubmed

A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland.

MYT1L LRP2

3.75e-04128428631881
Pubmed

ISL1 regulates lung branching morphogenesis via Shh signaling pathway.

IRX2 TBX2

3.75e-041284237442233
Pubmed

Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development.

INHA FST

4.42e-041384211557891
Pubmed

Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.

KLF12 SPP2 CTNNA2 ERICH6 IL7R

4.67e-0426584519240061
Pubmed

Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors.

FST GGT7

5.15e-041484216103213
Pubmed

Regulation of the ovarian reserve by members of the transforming growth factor beta family.

INHA FST

5.15e-041484222847922
Pubmed

Neuronal ceroid lipofuscinosis (nclf), a new disorder of the mouse linked to chromosome 9.

TEX2 GLO1

5.15e-04148429600738
Pubmed

Regulation of retinal interneuron subtype identity by the Iroquois homeobox gene Irx6.

BHLHE22 IRX6

5.93e-041584223172916
Pubmed

A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs.

DLL4 DNER

6.77e-041684235577801
Pubmed

Characterization of the development of the mouse cochlear epithelium at the single cell level.

FST TBX2

6.77e-041684232404924
Pubmed

Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo.

EPHB3 IRX2

6.77e-041684217638910
Pubmed

Role of topoisomerase IIbeta in the expression of developmentally regulated genes.

MYT1L CTNNA2

6.77e-041684216923961
Pubmed

Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

TNNI3K KLHL5 SPP2 EGR4 DNER CTNNA2

7.18e-0444284615815621
Pubmed

Target gene analysis by microarrays and chromatin immunoprecipitation identifies HEY proteins as highly redundant bHLH repressors.

DLL4 TBX2

7.66e-041784222615585
Pubmed

New genetic associations detected in a host response study to hepatitis B vaccine.

TRAF4 DNER TSPAN4 GRIN1 TNFRSF10A CARD14 TNFRSF11B IL7R

8.57e-0482484820237496
Pubmed

Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis.

MYT1L CTNNA2

8.60e-041884233323119
Pubmed

Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study.

TRIB1 PCSK9

9.60e-041984219148283
Pubmed

RNG105 deficiency impairs the dendritic localization of mRNAs for Na+/K+ ATPase subunit isoforms and leads to the degeneration of neuronal networks.

FXYD7 GRIN1

9.60e-041984220861386
Pubmed

Mesenchymal cells are required for functional development of thymic epithelial cells.

DLL4 IL7R

1.17e-032184217625108
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP2 LRP4

1.17e-032184221337463
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MYT1L ATRN MPRIP

1.24e-038784312465718
Pubmed

Identification of single nucleotide polymorphisms in the tumor necrosis factor (TNF) and TNF receptor superfamily in the Korean population.

TNFRSF10A TNFRSF11B

1.29e-032284215301860
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

SCYL2 FAM117A RBL1 INPP5E NISCH WRN HSPBP1 PRKG2 NCAPG2 MPRIP

1.30e-031321841027173435
Pubmed

Acheate-scute like 1 (Ascl1) is required for normal delta-like (Dll) gene expression and notch signaling during retinal development.

DLL4 BHLHE22

1.41e-032384219191219
Pubmed

Hand2 is an essential regulator for two Notch-dependent functions within the embryonic endocardium.

DLL4 IRX2

1.54e-032484225497097
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

SERPINB6 PLAA TEX2 GLYR1 GRIN1 CTNNA2 PEAK1 PPP6R2 GGT7

1.71e-03113984936417873
Pubmed

Vsx1 Transiently Defines an Early Intermediate V2 Interneuron Precursor Compartment in the Mouse Developing Spinal Cord.

DLL4 BHLHE22

1.80e-032684228082864
Pubmed

Cytokine and cytokine receptor single-nucleotide polymorphisms predict risk for non-small cell lung cancer among women.

TNFRSF10A IL7R

1.80e-032684219505916
Pubmed

Association of candidate gene polymorphisms with chronic kidney disease in Japanese individuals with hypertension.

WRN PCSK9

1.80e-032684219282863
Pubmed

Role of prophet of Pit1 (PROP1) in gonadotrope differentiation and puberty.

INHA FST

1.95e-032784216384867
Pubmed

Rhombomere-specific analysis reveals the repertoire of genetic cues expressed across the developing hindbrain.

FAM117A BHLHE22

1.95e-032784219208226
Pubmed

BMP receptor 1b is required for axon guidance and cell survival in the developing retina.

EPHB3 TBX2

1.95e-032784212654290
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

ZNF771 KLF12 MBNL2 EGR4 BHLHE22 TBX2

2.07e-0354484628473536
Pubmed

Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies.

MYT1L CTNNA2

2.09e-032884218839057
Pubmed

Genetic loci associated with lipid concentrations and cardiovascular risk factors in the Korean population.

TRIB1 PCSK9

2.24e-032984220972250
Pubmed

Seven new loci associated with age-related macular degeneration.

B3GLCT TNFRSF10A

2.24e-032984223455636
Cytoband16p13.3

ZSCAN10 WFIKKN1 GLYR1 ZNF213 SLX4

8.93e-0524484516p13.3
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF771 KLF12 ZNF211 ZSCAN10 ZBTB17 EGR4 ZNF425 ZNF184 ZNF213 ZNF224 REPIN1

1.04e-05718561128
GeneFamilyLow density lipoprotein receptors

LRP2 LRP4

7.19e-0413562634
GeneFamilyWAP four-disulfide core domain containing|Fibronectin type III domain containing

WFIKKN1 WFIKKN2

1.40e-0318562361
GeneFamilyTALE class homeoboxes and pseudogenes

IRX6 IRX2

2.92e-0326562526
GeneFamilyCD molecules|Tumor necrosis factor receptor superfamily|Death inducing signaling complex

TNFRSF10A TNFRSF11B

3.63e-0329562782
CoexpressionSTREICHER_LSM1_TARGETS_DN

RBL1 TNFRSF10A FST

2.86e-0519833M8637
CoexpressionNAGASHIMA_EGF_SIGNALING_UP

EGR4 DUSP1 TRIB1 TNFRSF11B

3.25e-0557834M16311
CoexpressionGSE45365_NK_CELL_VS_CD8_TCELL_DN

SERPINB6 CSRNP2 ZNF425 DUSP1 BHLHE22 TRIB1

3.28e-05191836M10008
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN

ZNF771 KLHL5 JTB ZBTB17 RBL1 NISCH ERCC6L2 HSPBP1 PEAK1 NCAPG2 TRIB1

3.31e-057768311M1107
ToppCellURO-Lymphocyte-T_NK-MAIT|URO / Disease, Lineage and Cell Type

ZNF425 RBL1 WFIKKN1 LTBP2 IL7R MPRIP

6.88e-07164846cb42a70433b3968caca67f7aa98ea536cd90a0bc
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK-ILC_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

KLF12 FXYD7 TOGARAM2 DNER CTNNA2 IL7R

1.15e-06179846d18a520568cf4b031972d3dd7d4d4bd073ac1fea
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L WFIKKN1 FXYD7 DNER CTNNA2 TBX2

2.00e-06197846a07e1a9b95c9f8a09452cbfe5a9f06648f66e29e
ToppCellSepsis-URO-Lymphocyte-T/NK-MAIT|URO / Disease, condition lineage and cell class

ZNF425 RBL1 WFIKKN1 LTBP2 IL7R MPRIP

2.06e-0619884675db638278d4be2b0f406cd8871058a8352c5a86
ToppCell10x5'-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3|bone_marrow / Manually curated celltypes from each tissue

FXYD7 LRP2 ERICH6 IL7R TBX2

1.13e-0515584583430a64c2cb5ad29caa3dacba76c28dd204ac40
ToppCellPND07-28-samps-Mesenchymal-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ELAPOR2 KLF12 LRP2 CARD14 TNFRSF11B

1.16e-05156845574f761962a7dd3308bd41fc529dd3ea1b8625f8
ToppCellPND07-28-samps-Mesenchymal-Mesothelial-Mesothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ELAPOR2 KLF12 LRP2 CARD14 TNFRSF11B

1.16e-05156845605d95a900e1443d3f6aae163ef2e893d3293203
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMPRSS9 CFAP57 IRX2 REPIN1 SLX4

1.20e-051578454766f7d545bf2d775390589460677519cb92f4d5
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DLL4 ERCC6L2 LRP2 CARD14 IL7R

1.57e-05166845f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCell390C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

KLHL5 FXYD7 TRIB1 IL7R TBX2

1.66e-05168845d8f485f8459532a2cb0bef899e6569142cf75685
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP4 LTBP2 FST TRIB1 TBX2

1.92e-05173845f9d6e892d66f9b94e4d5beb9f5dec9b606bc868a
ToppCellPND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP4 LTBP2 FST TRIB1 TBX2

1.92e-05173845cbd65dd5b01cc959e3ccbc89330ddd0122296ea3
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L FXYD7 DNER GRIN1 CTNNA2

2.08e-05176845116741fef5895ca85057d2d31eca9eba5764ab44
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L FXYD7 DNER GRIN1 CTNNA2

2.08e-051768455b707f58d164ee7a6a527dd5d053472ce9a631c1
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L TMPRSS9 FXYD7 DNER CTNNA2

2.38e-05181845fb4df9a128761abe5c6310a30d7b2f7f2fdef46d
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB17 BHLHE22 LTBP2 FST GGT7

2.51e-051838450e8fb371d8eac777451c76f41d53577f5dfb740d
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB17 BHLHE22 LTBP2 FST GGT7

2.51e-05183845cbc3b00faa7e4e0dbbbc8ee105467c65241c7470
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L FXYD7 DNER GRIN1 CTNNA2

2.64e-0518584594d0f283d63d932f310cc5a17ea893d71ba60f5e
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

RBL1 APBB2 LRP4 ZNF213 PPP6R2

2.71e-05186845de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR2 EGR4 INPP5E ZNF184 PRKG2

2.71e-05186845f5468e03321ea2083e223eb0d92c3a9307039569
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

RBL1 APBB2 LRP4 ZNF213 PPP6R2

2.71e-051868450b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell(6)_ILC|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

FXYD7 DNER TSPAN4 IL7R TBX2

2.85e-05188845de7cb273899d0e0748c85f45c6b5e7f0642ab057
ToppCell(6)_ILC|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

FXYD7 DNER TSPAN4 IL7R TBX2

2.85e-05188845f4734d5b703678670ece204a0519cf015e180a6e
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L TMPRSS9 FXYD7 DNER CTNNA2

2.93e-05189845cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF4 DUSP1 TRIB1 IL7R GGT7

3.00e-0519084584265be128170cbb08d76e824aa108e07da9c3e5
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L WFIKKN1 FXYD7 CTNNA2 TBX2

3.16e-05192845307d64ef7add6a2778733e9945a1bd687feb6f44
ToppCellPND01-03-samps-Mesenchymal|PND01-03-samps / Age Group, Lineage, Cell class and subclass

NISCH LRP4 PRKG2 PEAK1 TBX2

3.32e-051948454f9bd0ded0dde1df885850714f29e73e992539a5
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L FXYD7 DNER GRIN1 CTNNA2

3.40e-051958455a6a5048af638872700b76b7c71a8fa3fb8d3772
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

NISCH LRP4 PRKG2 PEAK1 TBX2

3.48e-0519684554f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L TMPRSS9 FXYD7 DNER CTNNA2

3.65e-0519884550504a3871f76d6a5b439a56450d7770f4501eb0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL5 SERPINB6 STARD9 PEAK1 DIPK2B

3.65e-051988450a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL5 SERPINB6 DLL4 TBX2 DIPK2B

3.74e-05199845dc88ce36cc066eb6c28cfd5b9b60fe07f8cc7b53
ToppCelldistal-Endothelial-Capillary_Aerocyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SERPINB6 DLL4 TSPAN4 TBX2 DIPK2B

3.83e-05200845b91f8eb67752a77e1e08e462e50f1b5923695e1b
ToppCellLPS-IL1RA-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

INPP5E LRP2 LRP4 ZNF213

9.81e-051278446b24630978eb0772b4cd3bf59e5bc4390be47619
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Rrad|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EGR4 BHLHE22 PRKG2 FST

1.35e-04138844b3a040c5d0e1cc94d9b19155bca8700edba2d243
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF771 KLHL5 ZNF211 DIPK2B

1.63e-04145844c0894c738815ff54790caddb4bccfa1503fd555b
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|367C / Donor, Lineage, Cell class and subclass (all cells)

MYT1L FXYD7 SLX4 IL7R

1.81e-04149844f18bddc84b064f3d57a1281d5172c404d87f25da
ToppCellAdult-Mesenchymal-myofibroblast_cell-D122|Adult / Lineage, Cell type, age group and donor

INHA OTOGL LTBP2 TBX2

2.27e-04158844410fa08c9d880d27e80ec939fa5ba5a41dcb31ab
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

ZNF771 KLF12 TRAF4 EGR4

2.38e-041608448aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCellSevere-Lymphoid-NK-CCR7+_T|Severe / Condition, Lineage, Cell class and cell subclass

ELAPOR2 KLF12 FXYD7 IL7R

2.56e-041638448f0d8c124f1569a5a6bc1db7581989f24d63cca3
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

ELAPOR2 OTOGL LRP2 PCSK9

2.62e-04164844beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

ELAPOR2 OTOGL LRP2 PCSK9

2.62e-04164844d005cfd821b87548b075120bffe65a0be9860463
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MYT1L EGR4 FXYD7 IL7R

2.80e-04167844b5d15773be32cd277125fd3b4056a8fefaefa5ec
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

DLL4 STARD9 TBX2 DIPK2B

2.80e-041678445af9127bae05768a5164d5708a4ad37edca99324
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

WFIKKN1 LRP2 IRX6 IRX2

2.80e-0416784425af48c640e67848594f5902867ba325fc105da4
ToppCelldroplet-Fat-Bat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 ATRN ZBTB17 PPP6R2

2.87e-041688446fddc957a0503455d8c165862b5eb8e5fdb8a510
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-ILC3|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DUSP1 TOGARAM2 FST IL7R

2.87e-041688444f2f78e14f044b535847bcdbbcec8c0fc8529870
ToppCelldroplet-Fat-Bat-18m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 ATRN ZBTB17 PPP6R2

2.87e-04168844794035cb63353a7d02fd9939deb5b4d075c9d95a
ToppCelldroplet-Fat-Bat-18m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 ATRN ZBTB17 PPP6R2

2.87e-041688441e23b634f96e88b976a523ca1f3fc08f6fe9b239
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1L OTOGL LRP2 LTBP2

2.93e-0416984412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

LIPH GRIN1 PRKG2 IRX2

3.00e-041708444cd3b7e43a061948084c01713ae141b5c2c07d89
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

LIPH GRIN1 PRKG2 IRX2

3.00e-0417084436c9f7f98612a72dc511c8da4358d67444f6bcf4
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_dendritic-mature_conventional_dendritic_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

EPHB3 DLL4 GRIN1 TNFRSF11B

3.07e-04171844d934d68efc5739483c735dc702ccd30b07a6aa7e
ToppCellnormal-na-Lymphocytic_NK-natural_killer_cell-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

MYT1L FRRS1 TOGARAM2 ZNF224

3.07e-04171844d339840626211a7bf1a9eb8f14d6c9509ab05e1c
ToppCellAT1_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

DUSP1 APBB2 PEAK1 IRX2

3.21e-041738443afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ELAPOR2 FRRS1 LIPH IRX2

3.21e-04173844ef8d720b99470fe1953661f6e66bc0366266bdb6
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LIPH APBB2 PRKG2 IRX2

3.21e-04173844b799c06a6a5754668e789f70c0c8bc1508568575
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-skeletal_muscle_satellite_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR2 OTOGL LRP2 TRIB1

3.28e-04174844f230d23618a6487f2664efb2c677e0a4559e2bf4
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DUSP1 NISCH PRKG2 PEAK1

3.28e-041748443c47d069bd836599a8d40eae485c23d4d3487517
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATRN LRP2 CFAP57 PCSK9

3.28e-041748444da79da7a09ee1e345102c5331675ebcdbe56171
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|343B / Donor, Lineage, Cell class and subclass (all cells)

WFIKKN1 SPRED1 CARD14 IL7R

3.35e-04175844d3890bd0c570bb81434fdd1c5229891cefe2e462
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

BHLHE22 LTBP2 TNFRSF11B TBX2

3.35e-04175844fed9e4120c758fdcc23bb248d1801002b0e0d485
ToppCell356C-Endothelial_cells-Endothelial-D|356C / Donor, Lineage, Cell class and subclass (all cells)

DLL4 NXF3 TNFRSF11B DIPK2B

3.50e-04177844a0b172f40e0df97a288a5549ae7066697ad469b3
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP4 LTBP2 FST TBX2

3.50e-0417784465709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCell367C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KLF12 REPIN1 TNFRSF11B IL7R

3.50e-04177844a0ff337f11bdb11959ac71805ff94be6b4ec1083
ToppCell356C-Endothelial_cells-Endothelial-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

DLL4 NXF3 TNFRSF11B DIPK2B

3.50e-04177844ab8f09e118e4df696b0b4d33f013da020bdbd351
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP4 LTBP2 FST TBX2

3.50e-041778448684d47a547e2a06496f15e8da0200ecddc431e0
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR2 EGR4 LRP2 PRKG2

3.57e-04178844d3cbdec9d75f076e565baca05ede292cca7758a4
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|343B / Donor, Lineage, Cell class and subclass (all cells)

WRN PEAK1 TNFRSF11B IL7R

3.57e-04178844ec6364432d37a32f5152d36d89f5e96dddb72a9d
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GRIN1 REPIN1 NCAPG2 TNFRSF11B

3.65e-041798444f20540bfbcefe0e83812be7ea542e8bb3bf19bc
ToppCelldroplet-Lung-nan-21m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN1 HSPBP1 REPIN1 TNFRSF11B

3.65e-04179844d78eacf47847a50888dd16c35bed9b7afc80010f
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Activated_DCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

EGR4 CARD14 TNFRSF11B IL7R

3.72e-04180844aae85fb3c92a45614616a3ee3a1af5244cc299a7
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP2 FST TNFRSF11B TBX2

3.72e-041808440153667e44fdbc3c0d444dcb023069925a2b69a2
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

KLHL5 SERPINB6 TBX2 DIPK2B

3.72e-04180844b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LTBP2 FST TNFRSF11B TBX2

3.72e-0418084440a28b410f46215d6d7cf8a02a18078eb046b5b0
ToppCellfacs-SCAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APBB2 PRKG2 FST IRX2

3.72e-041808446c70b6b7480507fa94625013222ad338ee7dd1d9
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|367C / Donor, Lineage, Cell class and subclass (all cells)

DLL4 TSPAN4 TBX2 DIPK2B

3.72e-04180844162cec1734e560c068cd61717e40e18dcf92308c
ToppCell10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-ILC_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

DUSP1 DNER CTNNA2 IL7R

3.72e-0418084427672ac6a02172a31851f18decb9acffa8f5a703
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|367C / Donor, Lineage, Cell class and subclass (all cells)

DLL4 TSPAN4 TBX2 DIPK2B

3.72e-0418084433c86c22ba877358cd8c1e39b5c0b3dc3a45b7dd
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLL4 BHLHE22 FST GGT7

3.72e-0418084479c5725f02e038d0187f4a1e1591f2492538aa57
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs|Myeloid_cells / Location, Cell class and cell subclass

KLF12 TRAF4 B3GLCT REPIN1

3.80e-04181844cc7ae1221a28bc404138a7efee0ad08a19cc3d86
ToppCelldroplet-Lung-nan-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR2 LIPH LRP2 IRX2

3.88e-04182844cfba75c1ffc39ac76db9e8e27394731942882b30
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE22 LTBP2 FST TBX2

3.88e-041828449edaccf1154cec92ca9a28e9b1f9075cfd422bfd
ToppCelldroplet-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR2 LIPH LRP2 IRX2

3.88e-04182844d836bfdc298ecd3558a973e393a329eb8bd59d79
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-pDC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMPRSS9 TRAF4 TEX2 GRIN1

3.88e-0418284402c0824373a0ecebc922d4ca848ace9d570722c4
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175|Adult / Lineage, Cell type, age group and donor

DLL4 STARD9 TBX2 DIPK2B

3.88e-041828448b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L DNER GRIN1 CTNNA2

3.88e-04182844be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCelldroplet-Lung-nan-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR2 LIPH LRP2 IRX2

3.88e-041828447e7c7a26460d3003cdf0c0ffb96208a566aa09a7
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BHLHE22 LTBP2 FST TBX2

3.88e-04182844aba4c06d5d7618ac21b2695bca8e7a1346a91090
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L FXYD7 DNER CTNNA2

3.96e-041838447e2bac8b005155888ff4b41ef2e1d975dc17abc7
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNNI3K TOGARAM2 DNER CFAP57

3.96e-0418384458847e8f3a7ce3e33adba9477bcd55e769a64a90
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MYT1L WFIKKN2 FXYD7 CTNNA2

3.96e-041838449dfb398b9995d562864fe688861a831ada0814cd
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BHLHE22 LTBP2 FST TBX2

4.05e-041848444cb5f299dd7413e0be1ad7af817ee614b23a18ae
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L FXYD7 DNER CTNNA2

4.05e-04184844abb61e744a9031e0c91eb560a8f486a0ca5a01cc
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TRAF4 LTBP2 FST TBX2

4.05e-0418484423c24ab5786af33d605bc445d06117b9da6c6331
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BHLHE22 LTBP2 FST TBX2

4.05e-0418484439bb0eb55bdc2cea46e41c7f21d8c5883f14e6bd
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TRAF4 LTBP2 FST TBX2

4.13e-04185844b1e84228c95be8ccf7c3c1afb66b71ffb93cf61e
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRRS1 LRP4 TNFRSF11B TBX2

4.22e-041868449d6cb36aa0aae69fe584dad31deafcfdcc9fd1db
ToppCellnormal_Lung-Myeloid_cells-Activated_DCs|normal_Lung / Location, Cell class and cell subclass

GRIN1 REPIN1 TNFRSF11B IL7R

4.22e-041868440987c9a39503eb6c75a2bf4db98b2b2fd46956fb
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYT1L FXYD7 DNER CTNNA2

4.22e-0418684424b23880d4ff8fb4a23e2012d5890b9e2fcf7283
DiseaseEye Diseases, Hereditary

INPP5E LRP2

1.05e-046792C0015398
Diseasesmoking status measurement, carotid artery intima media thickness

DNER TRIB1 PCSK9

2.93e-0448793EFO_0006527, EFO_0007117
Diseasepuberty, height growth measurement

TNNI3K PRKG2

1.18e-0319792EFO_0001382, EFO_0005201
Diseaseenergy expenditure measurement

KLF12 MBNL2

1.30e-0320792EFO_0008005
Diseasedilated cardiomyopathy (implicated_via_orthology)

DLL4 DNER LTBP2

1.31e-0380793DOID:12930 (implicated_via_orthology)
Diseaselipid measurement, lipoprotein measurement

PPP6R2 TRIB1 PCSK9

1.84e-0390793EFO_0004529, EFO_0004732
Diseasemiddle cerebral artery infarction (biomarker_via_orthology)

EGR4 GRIN1 IL7R

2.02e-0393793DOID:3525 (biomarker_via_orthology)
Diseaseoptic disc size measurement

KLF12 DUSP1 LRP2 FST

2.26e-03205794EFO_0004832
Diseasespontaneous preterm birth

MYT1L B3GLCT TBX2

2.55e-03101793EFO_0006917

Protein segments in the cluster

PeptideGeneStartEntry
ETSPKCEFCGSDLRA

ERICH6

266

Q7L0X2
DSCSINSDPEAKCFA

APBB2

406

Q92870
LLASKCRCYSNDAPD

B3GLCT

406

Q6Y288
ACSSTDPAALCKSEV

CSRNP2

461

Q9H175
AASCPEKCALFNSVS

BHLHE22

356

Q8NFJ8
RDADGAFTCCTNDKA

FAM117A

106

Q9C073
EVRTSIDACASSPCF

DLL4

476

Q9NR61
DRRICASASAPKTCS

DIPK2B

126

Q9H7Y0
RDSACDESSCIPKAF

IRX6

396

P78412
GEKCADRSPVCTTFS

NXF3

276

Q9H4D5
EEKNKSSCSFETCPR

MPRIP

496

Q6WCQ1
SPLACDDCSLRSAKS

INPP5E

241

Q9NRR6
SDKQDVLCLCFSPSE

CFAP57

336

Q96MR6
SGSAAAEAKECDRPC

ATRN

91

O75882
RCAPDEELLSCSSFS

PCSK9

476

Q8NBP7
DPFSAAAAECSCRQD

GGT7

91

Q9UJ14
LTDEAALSCCSDADP

GLO1

11

Q04760
ALSCCSDADPSTKDF

GLO1

16

Q04760
DFRLTSDKPCCEAGD

PEAK1

1326

Q9H792
VSTCDITFACVSDPK

GLYR1

321

Q49A26
ASACSRCDDNVEFVP

EPHB3

386

P54753
ACDAPILSSSRSLDC

IL7R

376

P16871
LCLSRSDAEETCPSF

LIPH

11

Q8WWY8
ADCLDASDEADCPTR

LRP2

3821

P98164
KAFACPVESCVRSFA

EGR4

481

Q05215
RCSLCDELCPDSKSD

FST

266

P19883
FSCDASPLLALSCSD

OR6Q1

181

Q8NGQ2
RDGSSCLKSVECFDP

KLHL5

616

Q96PQ7
TTNSKECELPAADSC

ELAPOR2

966

A8MWY0
SCSAESDGEKLPCRA

IRX2

231

Q9BZI1
PTSKFCVACVTEAFD

PRKG2

551

Q13237
AICPRDDSDCSLVSS

CARD14

436

Q9BXL6
ASSEFADDPCSSVKR

CTNNA2

106

P26232
EAFSASCPELCSKQS

DUSP1

126

P28562
ADKEFTRATCTDSCT

FRMPD2B

196

Q6IN97
CDPEKEASCVFLSFT

FRRS1

211

Q6ZNA5
DACDLCPSEDSAEFS

LTBP2

1446

Q14767
CRGAKDFASDPRCDT

FBXO24

181

O75426
TCSRSDEECKFAHPP

MBNL2

26

Q5VZF2
FPATDASCEDKSAAR

INHA

86

P05111
PFKCADCDRSFSRSD

KLF12

376

Q9Y4X4
PLAKEACDLCSDFSD

ERCC6L2

756

Q5T890
TTKPSEATFSCTCEE

DNER

326

Q8NFT8
EDSPSAALFEACCSD

PPP6R2

611

O75170
DDFPACTDKCDDSFV

OTOGL

381

Q3ZCN5
CEKLLQTCFSSPADD

HSPBP1

341

Q9NZL4
TLTAFSFDCAREACP

TOGARAM2

321

Q6ZUX3
DCDLEDATKTPDCSS

RBL1

906

P28749
CRKADSRSESPTCKS

FXYD7

51

P58549
GEKSCDFLSSFRDSC

SERPINB6

96

P35237
TCRKDSGEDPATCAF

SPP2

91

Q13103
SRDCLAFCTEPVFAS

SCYL2

111

Q6P3W7
KRRCFPGSEEICSSS

WRN

1371

Q14191
FVREKDCASLPSSCR

STARD9

131

Q9P2P6
DCASLPSSCRIKVSF

STARD9

136

Q9P2P6
ACPDCDRSFSQKSNL

REPIN1

516

Q9BWE0
SSCSSPSRDCQAERK

SLX4

956

Q8IY92
TSSADVRCSVFKCLP

NCAPG2

431

Q86XI2
VCKRCPDGFFSNETS

TNFRSF11B

141

O00300
DSDRRPFVCSDCGKA

ZSCAN10

461

Q96SZ4
PFVCSDCGKAFRRSE

ZSCAN10

466

Q96SZ4
CPECDKRFSAASNLR

ZNF771

121

Q7L3S4
AAVAAKCPRLSECSS

TRIB1

41

Q96RU8
CKPERDGAESDASSC

TBX2

311

Q13207
DFSDPCSCDTSDDKF

SPRED1

386

Q7Z699
SSICSEHFTPDCFKR

THAP1

51

Q9NVV9
RRSCCAPSEAVKSAA

NISCH

891

Q9Y2I1
SSVSEPAKVSECCRF

PLAA

776

Q9Y263
VSVEFCSACARKASS

CREBZF

336

Q9NS37
KEVPALDAACCRAAS

TMPRSS9

16

Q7Z410
TGERPVECSECSKSF

ZNF211

476

Q13398
DSCNTALVLCPFKDS

TRAF4

241

Q9BUZ4
LFACLPCTACKSDEE

TNFRSF10A

161

O00220
NATRVPDSCCLEFSE

TSPAN4

161

O14817
CRDRCEKEPSFTCAS

WFIKKN1

116

Q96NZ8
EKPFSCRECSKAFSD

ZBTB17

331

Q13105
CRECSKAFSDPAACK

ZBTB17

336

Q13105
KCPECDKSFRSSSDL

ZNF213

346

O14771
TAEKPFRCDTCDKSF

ZNF224

311

Q9NZL3
CRPRAFCLADSDEES

TEX2

936

Q8IWB9
CDPSRSSGEKDEQTC

TNNI3K

371

Q59H18
TTEKPFSCAECGRSF

ZNF425

521

Q6IV72
PFKCDECDKTFTRST

ZNF184

361

Q99676
DRCEKEPSFTCASDG

WFIKKN2

136

Q8TEU8
VAEECSPCSNFRAKT

JTB

56

O76095
RASDFVCACPDEPDS

LRP4

1631

O75096
PRSRVFASCAKEDGC

MYT1L

391

Q9UL68
LLFSCSVARAACDPK

GRIN1

11

Q05586