Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	steroid hormone binding	ESR2 ATP1A1 ATP1A3	4.60e-06	7	103	3	GO:1990239
GeneOntologyMolecularFunction	D-dopachrome decarboxylase activity	DDT DDTL	2.64e-05	2	103	2	GO:0033981
GeneOntologyMolecularFunction	phenylpyruvate tautomerase activity	DDT DDTL	7.88e-05	3	103	2	GO:0050178
GeneOntologyMolecularFunction	intramolecular oxidoreductase activity, interconverting keto- and enol-groups	DDT DDTL	1.57e-04	4	103	2	GO:0016862
GeneOntologyMolecularFunction	estradiol binding	ATP5PO ESR2	1.57e-04	4	103	2	GO:1903924
GeneOntologyMolecularFunction	steroid binding	ATP5PO ESR2 OSBPL5 ATP1A1 ATP1A3	6.31e-04	133	103	5	GO:0005496
GeneOntologyMolecularFunction	P-type transmembrane transporter activity	ATP2C1 ATP1A1 ATP1A3	8.41e-04	36	103	3	GO:0140358
GeneOntologyMolecularFunction	P-type ion transporter activity	ATP2C1 ATP1A1 ATP1A3	8.41e-04	36	103	3	GO:0015662
GeneOntologyMolecularFunction	P-type sodium transporter activity	ATP1A1 ATP1A3	1.15e-03	10	103	2	GO:0008554
GeneOntologyMolecularFunction	P-type sodium:potassium-exchanging transporter activity	ATP1A1 ATP1A3	1.15e-03	10	103	2	GO:0005391
GeneOntologyMolecularFunction	arachidonate-CoA ligase activity	ACSL6 ACSL5	1.41e-03	11	103	2	GO:0047676
GeneOntologyMolecularFunction	P-type potassium transmembrane transporter activity	ATP1A1 ATP1A3	1.41e-03	11	103	2	GO:0008556
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase binding	PIK3AP1 PDGFRB ATP1A1	1.42e-03	43	103	3	GO:0043548
GeneOntologyCellularComponent	photoreceptor inner segment membrane	ATP1A1 ATP1A3	1.43e-04	4	103	2	GO:0060342
Domain	-	ATP2C1 ATP1A1 ATP1A3	8.17e-05	16	101	3	1.20.1110.10
Domain	ATPase_P-typ_TM_dom	ATP2C1 ATP1A1 ATP1A3	8.17e-05	16	101	3	IPR023298
Domain	Macrophage_inhib_fac	DDT DDTL	8.66e-05	3	101	2	PD004816
Domain	MITF_TFEB_C_3_N	TFEB MITF	8.66e-05	3	101	2	PF15951
Domain	MiT/TFE_N	TFEB MITF	8.66e-05	3	101	2	IPR031867
Domain	Macrophage_inhib_fac_CS	DDT DDTL	8.66e-05	3	101	2	IPR019829
Domain	Macrophage_inhib_fac	DDT DDTL	8.66e-05	3	101	2	IPR001398
Domain	Tautomerase/MIF_sf	DDT DDTL	8.66e-05	3	101	2	IPR014347
Domain	MIF	DDT DDTL	8.66e-05	3	101	2	PS01158
Domain	MIF	DDT DDTL	8.66e-05	3	101	2	PF01187
Domain	ATPase_P-typ_cation-transptr_C	ATP2C1 ATP1A1 ATP1A3	9.88e-05	17	101	3	IPR006068
Domain	Cation_ATPase_C	ATP2C1 ATP1A1 ATP1A3	9.88e-05	17	101	3	PF00689
Domain	Cation_ATPase_N	ATP2C1 ATP1A1 ATP1A3	1.18e-04	18	101	3	PF00690
Domain	Cation_ATPase_N	ATP2C1 ATP1A1 ATP1A3	1.18e-04	18	101	3	SM00831
Domain	ATPase_P-typ_cation-transptr_N	ATP2C1 ATP1A1 ATP1A3	1.40e-04	19	101	3	IPR004014
Domain	DUF3371	TFEB MITF	1.73e-04	4	101	2	PF11851
Domain	MiT/TFE_C	TFEB MITF	1.73e-04	4	101	2	IPR021802
Domain	P-type_ATPase_IIC	ATP1A1 ATP1A3	4.28e-04	6	101	2	IPR005775
Domain	P_typ_ATPase	ATP2C1 ATP1A1 ATP1A3	9.63e-04	36	101	3	IPR001757
Domain	ATPase_P-typ_P_site	ATP2C1 ATP1A1 ATP1A3	9.63e-04	36	101	3	IPR018303
Domain	ATPASE_E1_E2	ATP2C1 ATP1A1 ATP1A3	9.63e-04	36	101	3	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP2C1 ATP1A1 ATP1A3	1.04e-03	37	101	3	IPR008250
Domain	E1-E2_ATPase	ATP2C1 ATP1A1 ATP1A3	1.04e-03	37	101	3	PF00122
Domain	START	STARD8 STARD9	2.90e-03	15	101	2	PF01852
Domain	Bbox_C	MID2 TRIM66	2.90e-03	15	101	2	IPR003649
Domain	BBC	MID2 TRIM66	2.90e-03	15	101	2	SM00502
Domain	START_lipid-bd_dom	STARD8 STARD9	2.90e-03	15	101	2	IPR002913
Domain	START	STARD8 STARD9	2.90e-03	15	101	2	PS50848
Domain	Ig_I-set	HSPG2 VSIG2 PDGFRB UNC5B KIRREL1	3.72e-03	190	101	5	IPR013098
Domain	I-set	HSPG2 VSIG2 PDGFRB UNC5B KIRREL1	3.72e-03	190	101	5	PF07679
Domain	bHLH_dom	TFEB CDC42BPG STRA8 MITF	3.86e-03	118	101	4	IPR011598
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MON2 ACSL6 SNPH RAP1GAP2 CEP192 USP19 KLHL29 KIDINS220 MEGF9 STARD9 DISP2 BOD1L1 TRAK2	3.80e-10	407	106	13	12693553
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	USP53 TFEB KIAA0930 GAPVD1 SASH1 HJURP CEP192 SHKBP1 CDCA2 CLMN STARD9 MAP3K10 BOD1L1 WNK3	3.76e-07	861	106	14	36931259
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP53 GAPVD1 SASH1 SERTAD2 TRIOBP DIDO1 FNDC3A TECPR2 ARHGAP31 TTLL4 OSBPL5	6.88e-07	529	106	11	14621295
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	USP53 CDC42BPG MID2 TRIOBP CEP192 RBBP8NL DDT SHKBP1 HIPK3 KLHL29 ATP2C1 KIDINS220 TECPR2 CLMN MICAL2 OSBPL5 BOD1L1	2.63e-06	1489	106	17	28611215
Pubmed	Retinal pigment epithelial integrity is compromised in the developing albino mouse retina.	MITF ATP1A1 ATP1A3	5.93e-06	12	106	3	27097562
Pubmed	Molecular Etiology of Hereditary Single-Side Deafness: Its Association With Pigmentary Disorders and Waardenburg Syndrome.	MITF PAX3	9.20e-06	2	106	2	26512583
Pubmed	Daidzein down-regulates ubiquitin-specific protease 19 expression through estrogen receptor β and increases skeletal muscle mass in young female mice.	ESR2 USP19	9.20e-06	2	106	2	28886438
Pubmed	Immunohistochemical analyses of alpha1 and alpha3 Na+/K+-ATPase subunit expression in medulloblastomas.	ATP1A1 ATP1A3	9.20e-06	2	106	2	21498719
Pubmed	Duplicated zinc finger protein genes on the proximal short arm of the human X chromosome: isolation, characterization and X-inactivation studies.	ZXDA ZXDB	9.20e-06	2	106	2	8268913
Pubmed	The value of MLPA in Waardenburg syndrome.	MITF PAX3	9.20e-06	2	106	2	17627390
Pubmed	[Clinical and molecular genetic investigation of Waardenburg syndrome type 1].	MITF PAX3	9.20e-06	2	106	2	12666593
Pubmed	Transcription factors in melanocyte development: distinct roles for Pax-3 and Mitf.	MITF PAX3	9.20e-06	2	106	2	11231058
Pubmed	Epistatic relationship between Waardenburg syndrome genes MITF and PAX3.	MITF PAX3	9.20e-06	2	106	2	9500554
Pubmed	All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides.	ATP1A1 ATP1A3	9.20e-06	2	106	2	11546672
Pubmed	PAX3 knockdown in metastatic melanoma cell lines does not reduce MITF expression.	MITF PAX3	9.20e-06	2	106	2	21164369
Pubmed	Overlapping ATP2C1 and ASTE1 genes in human genome: implications for SPCA1 expression?	ASTE1 ATP2C1	9.20e-06	2	106	2	23344038
Pubmed	Properties and expression of Na+/K+-ATPase α-subunit isoforms in the brain of the swamp eel, Monopterus albus, which has unusually high brain ammonia tolerance.	ATP1A1 ATP1A3	9.20e-06	2	106	2	24391932
Pubmed	Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons.	ATP1A1 ATP1A3	9.20e-06	2	106	2	23761886
Pubmed	The mutational spectrum in Waardenburg syndrome.	MITF PAX3	9.20e-06	2	106	2	8589691
Pubmed	P-Rex1 cooperates with PDGFRβ to drive cellular migration in 3D microenvironments.	PDGFRB PREX1	9.20e-06	2	106	2	23382862
Pubmed	The family of human Na+,K+-ATPase genes. A partial nucleotide sequence related to the alpha-subunit.	ATP1A1 ATP1A3	9.20e-06	2	106	2	3030810
Pubmed	Cloning of the mouse gene for D-dopachrome tautomerase.	DDT DDTL	9.20e-06	2	106	2	9858785
Pubmed	Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes.	TFEB MITF	9.20e-06	2	106	2	23401004
Pubmed	Distribution maps of D-dopachrome tautomerase in the mouse brain.	DDT DDTL	9.20e-06	2	106	2	23000624
Pubmed	Double heterozygous mutations of MITF and PAX3 result in Waardenburg syndrome with increased penetrance in pigmentary defects.	MITF PAX3	9.20e-06	2	106	2	22320238
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SNPH DIDO1 ZNF518A TRIM66 TECPR2	1.73e-05	104	106	5	9205841
Pubmed	Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications.	ATP1A1 ATP1A3	2.76e-05	3	106	2	2822726
Pubmed	Na+/K+-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes.	ATP1A1 ATP1A3	2.76e-05	3	106	2	30819023
Pubmed	"Near Cure" treatment of severe acute EAE in MIF-1-deficient female and male mice with a bifunctional MHCII-derived molecular construct.	DDT DDTL	2.76e-05	3	106	2	35738135
Pubmed	Mouse and hamster mutants as models for Waardenburg syndromes in humans.	MITF PAX3	2.76e-05	3	106	2	2246770
Pubmed	Glycoprotein nonmetastatic melanoma protein B (GPNMB) promotes the progression of brain glioblastoma via Na+/K+-ATPase.	ATP1A1 ATP1A3	2.76e-05	3	106	2	27836549
Pubmed	Identification of a VxP Targeting Signal in the Flagellar Na+ /K+ -ATPase.	ATP1A1 ATP1A3	2.76e-05	3	106	2	26373354
Pubmed	Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment.	DDT DDTL	2.76e-05	3	106	2	25016026
Pubmed	Conserved gene structure and genomic linkage for D-dopachrome tautomerase (DDT) and MIF.	DDT DDTL	2.76e-05	3	106	2	9716662
Pubmed	Differential expression of Na+/K+-ATPase alpha-subunits in mouse hippocampal interneurones and pyramidal cells.	ATP1A1 ATP1A3	2.76e-05	3	106	2	17947306
Pubmed	Novel mutations of PAX3, MITF, and SOX10 genes in Chinese patients with type I or type II Waardenburg syndrome.	MITF PAX3	2.76e-05	3	106	2	20478267
Pubmed	Association between sodium- and potassium-activated adenosine triphosphatase alpha isoforms and bipolar disorders.	ATP1A1 ATP1A3	2.76e-05	3	106	2	19058785
Pubmed	Knockout of sodium pump α3 subunit gene (Atp1a3-/-) results in perinatal seizure and defective respiratory rhythm generation.	ATP1A1 ATP1A3	2.76e-05	3	106	2	28465228
Pubmed	Developmental cell-specific regulation of Na(+)-K(+)-ATPase alpha 1-, alpha 2-, and alpha 3-isoform gene expression.	ATP1A1 ATP1A3	2.76e-05	3	106	2	8203495
Pubmed	Phosphorylation of BRN2 modulates its interaction with the Pax3 promoter to control melanocyte migration and proliferation.	MITF PAX3	2.76e-05	3	106	2	22290434
Pubmed	Na,K-ATPase and the role of alpha isoforms in behavior.	ATP1A1 ATP1A3	2.76e-05	3	106	2	18044013
Pubmed	Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na+/K+-ATPase.	ATP1A1 ATP1A3	2.76e-05	3	106	2	26988030
Pubmed	MITF and TFEB cross-regulation in melanoma cells.	TFEB MITF	2.76e-05	3	106	2	32881934
Pubmed	Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model.	ATP1A1 ATP1A3	2.76e-05	3	106	2	26911348
Pubmed	Genetic regulation of gene expression of MIF family members in lung tissue.	DDT DDTL	2.76e-05	3	106	2	33046825
Pubmed	Cardiac glycosides induced toxicity in human cells expressing α1-, α2-, or α3-isoforms of Na-K-ATPase.	ATP1A1 ATP1A3	2.76e-05	3	106	2	25994790
Pubmed	Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer.	DDT DDTL	2.76e-05	3	106	2	37464010
Pubmed	Estrogen receptor beta modulates permeability transition in brain mitochondria.	ATP5PO ESR2	2.76e-05	3	106	2	29550215
Pubmed	Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2.	ATP1A1 ATP1A3	5.50e-05	4	106	2	21731499
Pubmed	The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice.	ATP1A1 ATP1A3	5.50e-05	4	106	2	12458206
Pubmed	Novel transcription factors in human CD34 antigen-positive hematopoietic cells.	DIDO1 CGRRF1	5.50e-05	4	106	2	12070015
Pubmed	Cloning and characterization of the murine genes for bHLH-ZIP transcription factors TFEC and TFEB reveal a common gene organization for all MiT subfamily members.	TFEB MITF	5.50e-05	4	106	2	10036191
Pubmed	Identification of nine novel variants across PAX3, SOX10, EDNRB, and MITF genes in Waardenburg syndrome with next-generation sequencing.	MITF PAX3	5.50e-05	4	106	2	36331148
Pubmed	Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.	ATP1A1 ATP1A3	5.50e-05	4	106	2	21849490
Pubmed	Muscle Na+-K+-ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes.	ATP1A1 ATP1A3	5.50e-05	4	106	2	17446412
Pubmed	The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF).	DDT DDTL	5.50e-05	4	106	2	21817065
Pubmed	Cooperative regulation of non-small cell lung carcinoma angiogenic potential by macrophage migration inhibitory factor and its homolog, D-dopachrome tautomerase.	DDT DDTL	5.50e-05	4	106	2	18684922
Pubmed	Na,K-ATPase expression in the mouse cochlea is not dependent on the mineralocorticoid receptor.	ATP1A1 ATP1A3	5.50e-05	4	106	2	11591489
Pubmed	Cardiomyocyte d-dopachrome tautomerase protects against heart failure.	DDT DDTL	5.50e-05	4	106	2	31484822
Pubmed	Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development.	TFEB MITF	5.50e-05	4	106	2	11930005
Pubmed	Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1.	ATP1A1 ATP1A3	5.50e-05	4	106	2	19751721
Pubmed	Agrin regulation of alpha3 sodium-potassium ATPase activity modulates cardiac myocyte contraction.	ATP1A1 ATP1A3	5.50e-05	4	106	2	19376779
Pubmed	Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice.	ATP1A1 ATP1A3	5.50e-05	4	106	2	17234593
Pubmed	Family of Na+,K+-ATPase genes. Intra-individual tissue-specific restriction fragment length polymorphism.	ATP1A1 ATP1A3	5.50e-05	4	106	2	2887455
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	USP53 UNC5B PARP14 KIDINS220 ARHGAP31 MICAL2 KIRREL1 ATP1A1 KDF1	6.34e-05	569	106	9	30639242
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	MON2 PIK3AP1 GAPVD1 FNDC3A CLMN TTLL4 ZFAND6 KIRREL1 DCLRE1A BOD1L1	8.41e-05	733	106	10	34672954
Pubmed	Structure and organization of the human theta-class glutathione S-transferase and D-dopachrome tautomerase gene complex.	DDT DDTL	9.15e-05	5	106	2	9729470
Pubmed	Multiple genes encode the human Na+,K+-ATPase catalytic subunit.	ATP1A1 ATP1A3	9.15e-05	5	106	2	3035563
Pubmed	TWEAK increases CD74 expression and sensitizes to DDT proinflammatory actions in tubular cells.	DDT DDTL	9.15e-05	5	106	2	29924850
Pubmed	Estrogen regulation of germline stem cell differentiation as a mechanism contributing to female reproductive aging.	ESR2 STRA8	9.15e-05	5	106	2	32302290
Pubmed	The vestigial enzyme D-dopachrome tautomerase protects the heart against ischemic injury.	DDT DDTL	9.15e-05	5	106	2	24983315
Pubmed	Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family.	ACSL6 ACSL5	9.15e-05	5	106	2	15292367
Pubmed	mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases.	TFEB MITF	9.15e-05	5	106	2	28165011
Pubmed	Identification of acyl-CoA synthetases involved in the mammalian sphingosine 1-phosphate metabolic pathway.	ACSL6 ACSL5	9.15e-05	5	106	2	24269233
Pubmed	Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling.	TFEB SMCR8	9.15e-05	5	106	2	27875531
Pubmed	Sumoylation of MITF and its related family members TFE3 and TFEB.	TFEB MITF	9.15e-05	5	106	2	15507434
Pubmed	The Sjögren-Larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway.	ACSL6 ACSL5	9.15e-05	5	106	2	22633490
Pubmed	Biology, structure and mechanism of P-type ATPases.	ATP2C1 ATP1A1 ATP1A3	9.49e-05	29	106	3	15071553
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	USP53 ATP2C1 STARD9 BOD1L1 PREX1	1.09e-04	153	106	5	10718198
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	GAPVD1 STARD8 HJURP DIDO1 TACC2 CEP192 FAM171B ANKRD6 CLMN TTLL4 BOD1L1 ZNF445	1.18e-04	1084	106	12	11544199
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	GAPVD1 CEP192 FAM171B USP19 CDCA2 KIDINS220 KIRREL1 DCLRE1A ATP1A1 SMCR8	1.35e-04	777	106	10	35844135
Pubmed	The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.	ATP1A1 ATP1A3	1.37e-04	6	106	2	3036582
Pubmed	Physical mapping of the evolutionary boundary between human chromosomes 21 and 22 on mouse chromosome 10.	DDT DDTL	1.37e-04	6	106	2	9628829
Pubmed	Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently.	TFEB MITF	1.37e-04	6	106	2	9510032
Pubmed	MIF but not MIF-2 recruits inflammatory macrophages in an experimental polymicrobial sepsis model.	DDT DDTL	1.37e-04	6	106	2	34850744
Pubmed	Over-expression of the chondroitin sulphate proteoglycan versican is associated with defective neural crest migration in the Pax3 mutant mouse (splotch).	HSPG2 PAX3	1.37e-04	6	106	2	9486530
Pubmed	Dissection of a signaling pathway by which pathogen-associated molecular patterns recruit the JNK and p38 MAPKs and trigger cytokine release.	GCK MAP3K10	1.37e-04	6	106	2	17584736
Pubmed	Transport and pharmacological properties of nine different human Na, K-ATPase isozymes.	ATP1A1 ATP1A3	1.37e-04	6	106	2	10636900
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MON2 TFEB HSPG2 KIAA0930 RAP1GAP2 CEP192 EIF6 TTLL4 IFRD2 OSBPL5 DISP2 PREX1	1.41e-04	1105	106	12	35748872
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	GAPVD1 ATP5PO FNDC3A USP19 ATP2C1 KIDINS220 KIRREL1 ATP1A1 ATP1A3 FUT8 WNK3	1.45e-04	942	106	11	31073040
Pubmed	Differential involvement of Na(+),K(+)-ATPase isozymes in preimplantation development of the mouse.	ATP1A1 ATP1A3	1.91e-04	7	106	2	10837135
Pubmed	Molecular genetics of Na,K-ATPase.	ATP1A1 ATP1A3	1.91e-04	7	106	2	2158121
Pubmed	[Hereditary hypomelanocytoses: the role of PAX3, SOX10, MITF, SNAI2, KIT, EDN3 and EDNRB genes].	MITF PAX3	1.91e-04	7	106	2	24379252
Pubmed	MIF-2/D-DT enhances proximal tubular cell regeneration through SLPI- and ATF4-dependent mechanisms.	DDT DDTL	1.91e-04	7	106	2	28539339
Pubmed	Expression and distribution of Na, K-ATPase isoforms in the human uterus.	ATP1A1 ATP1A3	1.91e-04	7	106	2	20065300
Pubmed	Endothelial Unc5B controls blood-brain barrier integrity.	PDGFRB UNC5B	1.91e-04	7	106	2	35246514
Pubmed	Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart.	ACSL6 ACSL5	1.91e-04	7	106	2	17197235
Pubmed	Deletion in the N-terminal half of olfactomedin 1 modifies its interaction with synaptic proteins and causes brain dystrophy and abnormal behavior in mice.	TRIOBP USP19 KIDINS220	2.32e-04	39	106	3	24095980
Pubmed	Cited2 is required in trophoblasts for correct placental capillary patterning.	PDGFRB ATP1A1	2.55e-04	8	106	2	24803182
Pubmed	CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart.	LPA ATP1A1	2.55e-04	8	106	2	36577382
Interaction	YWHAH interactions	USP53 TFEB CDC42BPG KIAA0930 GAPVD1 SASH1 ESR2 HJURP CEP192 SHKBP1 CDCA2 CLMN STARD9 MITF OSBPL5 MAP3K10 DCLRE1A BOD1L1 WNK3	2.37e-06	1102	102	19	int:YWHAH
Interaction	GORASP1 interactions	MON2 ESR2 FNDC3A HIPK3 GORASP1 SMCR8	1.39e-05	103	102	6	int:GORASP1
GeneFamily	ATPase Na+/K+ transporting subunits	ATP1A1 ATP1A3	2.72e-04	7	66	2	1208
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HSPG2 VSIG2 PDGFRB UNC5B KIRREL1	3.03e-04	161	66	5	593
GeneFamily	StAR related lipid transfer domain containing	STARD8 STARD9	1.34e-03	15	66	2	759
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRO PTPRQ	2.64e-03	21	66	2	813
GeneFamily	Fibronectin type III domain containing	MID2 FNDC3A PTPRO PTPRQ	2.78e-03	160	66	4	555
GeneFamily	Acyl-CoA synthetase family	ACSL6 ACSL5	4.03e-03	26	66	2	40
Coexpression	CUI_TCF21_TARGETS_2_DN	CDC42BPG STARD8 KDM4C FNDC3A PARP14 ZFX ZNF518A HIPK3 ZBTB44 PTPRO ARHGAP31 OSBPL5 KIRREL1 TRAK2	8.03e-06	854	105	14	M1533
Coexpression	CUI_TCF21_TARGETS_2_DN	CDC42BPG STARD8 KDM4C FNDC3A PARP14 ZFX ZNF518A HIPK3 ZBTB44 PTPRO ARHGAP31 OSBPL5 KIRREL1 TRAK2	1.25e-05	888	105	14	MM1018
Coexpression	GSE42021_TREG_PLN_VS_TREG_PRECURSORS_THYMUS_UP	TRIOBP CEP192 MEGF9 CGRRF1 DCLRE1A TRAK2 MUC2	1.49e-05	197	105	7	M9569
Coexpression	TABULA_MURIS_SENIS_TRACHEA_GRANULOCYTE_AGEING	KIAA0930 DIDO1 HIPK3 ACSL5	2.66e-05	43	105	4	MM3857
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#2_top-relative-expression-ranked_1000	GAPVD1 ANKRD10 HJURP DIDO1 FAM171B CDCA2 MEGF9 ARHGAP31 CLMN STARD9 ZNF445	9.97e-08	284	100	11	gudmap_developingGonad_e16.5_epididymis_1000_k2
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_1000	GAPVD1 ANKRD10 HJURP DIDO1 FNDC3A CDCA2 CLMN ZNF445	5.00e-05	277	100	8	gudmap_developingGonad_e12.5_ovary_k3_1000
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRB UNC5B FAM171B KLHL29 ADAMTS15 KIRREL1 DISP2	3.07e-07	185	106	7	f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRB UNC5B FAM171B KLHL29 ADAMTS15 KIRREL1 DISP2	3.07e-07	185	106	7	40e958511790e84321da5ccf735f9974c06a0263
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRB UNC5B FAM171B KLHL29 ADAMTS15 KIRREL1 DISP2	3.07e-07	185	106	7	5f2eeba80aff145e85cfd81e2890a155406badb9
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	MON2 USP53 FNDC3A TACC2 CLMN BOD1L1 ATP1A1	3.54e-07	189	106	7	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	TFEB SFTA3 SNPH VSIG2 PCLO TACC2	4.19e-06	177	106	6	ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	TFEB SFTA3 SNPH VSIG2 PCLO TACC2	4.19e-06	177	106	6	d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	PCLO RAP1GAP2 FAM171B HIPK3 KIDINS220 DISP2	4.47e-06	179	106	6	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	SFTA3 PCLO TACC2 MEGF9 MICAL2 FHIP1A	6.49e-06	191	106	6	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 SASH1 MID2 ARHGAP31 MICAL2 ATP1A1	7.09e-06	194	106	6	f159ef8541d75a4e98468947f231bb463bec922c
ToppCell	facs-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD8 SASH1 MID2 UNC5B HJURP MICAL2	7.30e-06	195	106	6	7f9b7f15006610ad591063d90e90367bd6083c7f
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SFTA3 TACC2 MEGF9 MICAL2 ATP1A1 FHIP1A	8.20e-06	199	106	6	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	KIAA0930 RAP1GAP2 ARHGAP31 MITF ZFAND6	3.27e-05	153	106	5	e7d20c88466ff81db613869cf7a6a4bb95fd6c2f
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANKRD31 PDGFRB CLMN MAP3K10 DCLRE1A	4.43e-05	163	106	5	8f24cef152f5965727bbeee116bd26c75cbba82a
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NEK5 ARHGAP31 ATP1A3 RBFA ZNF445	4.43e-05	163	106	5	0ab043b68e8739adcedda01165a3758cd0d22728
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KLHL29 PTPRO PTPRQ KIRREL1	5.71e-05	172	106	5	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP53 HSPG2 HJURP FAM171B KLHL29	5.87e-05	173	106	5	8bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP53 HSPG2 HJURP FAM171B KLHL29	5.87e-05	173	106	5	3e3c61468e703330788a10d850ef41a85680f86d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KLHL29 PTPRO PTPRQ KIRREL1	6.04e-05	174	106	5	dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 SASH1 PARP14 STARD9 PREX1	6.72e-05	178	106	5	375156ba1c7b8592bf733c75f24968161f7cfa09
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SFTA3 ESR2 TACC2 FUT8 FHIP1A	6.72e-05	178	106	5	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	renal_papilla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 HSPG2 SASH1 ESR2 FUT8	7.09e-05	180	106	5	49829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 STARD8 VSIG2 UNC5B DISP2	7.27e-05	181	106	5	4df7972f88117108698efd06b124b232f8588981
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3AP1 SASH1 KLHL29 ADAMTS15 FUT8	7.27e-05	181	106	5	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 STARD8 VSIG2 UNC5B DISP2	7.27e-05	181	106	5	cbb530566893281289026bfd93adf721decd4ca3
ToppCell	COVID-19-kidney-Podocyte\|kidney / Disease (COVID-19 only), tissue and cell type	PDGFRB KLHL29 PTPRO PTPRQ KIRREL1	7.66e-05	183	106	5	fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KLHL29 PTPRO PTPRQ KIRREL1	7.66e-05	183	106	5	3c516fe5083f02bad1f464ed284010b4131a833c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KLHL29 PTPRO PTPRQ KIRREL1	7.66e-05	183	106	5	612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KLHL29 PTPRO PTPRQ KIRREL1	7.66e-05	183	106	5	848fc6dd129150897ee339343e83c645b6e779eb
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KLHL29 PTPRO PTPRQ KIRREL1	7.66e-05	183	106	5	9c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCell	COVID-19-lung-AT1\|lung / Disease (COVID-19 only), tissue and cell type	SFTA3 TACC2 MEGF9 MICAL2 FHIP1A	7.66e-05	183	106	5	942530449e9c6583705eeb8f6f12621daea57252
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KLHL29 PTPRO PTPRQ KIRREL1	7.66e-05	183	106	5	7c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSL6 PCLO GCK ANKRD6 DISP2	7.86e-05	184	106	5	3da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KLHL29 PTPRO PTPRQ KIRREL1	7.86e-05	184	106	5	7294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KLHL29 PTPRO PTPRQ KIRREL1	8.06e-05	185	106	5	9197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KLHL29 PTPRO PTPRQ KIRREL1	8.06e-05	185	106	5	ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KLHL29 PTPRO PTPRQ KIRREL1	8.06e-05	185	106	5	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	10x5'-GI_small-bowel-Myeloid_Monocytic-Nonclassical_monocytes\|GI_small-bowel / Manually curated celltypes from each tissue	PIK3AP1 STARD8 PTPRO CLMN MITF	8.27e-05	186	106	5	a16ecf70271894a842925f232009e2623d16947e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 SASH1 ARHGAP31 STARD9 PREX1	8.48e-05	187	106	5	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SFTA3 TACC2 MEGF9 ATP1A1 FHIP1A	8.48e-05	187	106	5	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_NK-Cycling_NK\|GI_small-bowel / Manually curated celltypes from each tissue	PDGFRB HJURP CDCA2 OSBPL5 WNK3	8.48e-05	187	106	5	265c690c2921fd201361a0ec8bc4d2a996fbcaf4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 UNC5B ARHGAP31 FUT8 PREX1	9.14e-05	190	106	5	bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCLO RAP1GAP2 FNDC3A GCK ATP1A1	9.37e-05	191	106	5	fd01a206763dfb6d52cca67123571936b4a8e1a0
ToppCell	PCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SFTA3 RAP1GAP2 RBBP8NL MITF FHIP1A	9.37e-05	191	106	5	05731ece7867659c662f952812805f947032fe10
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	MON2 GAPVD1 PARP14 KIDINS220 FUT8	9.37e-05	191	106	5	9454f642c3621370fa23640b631301346b300950
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SFTA3 TACC2 MEGF9 ATP1A1 FHIP1A	9.60e-05	192	106	5	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	PCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SFTA3 VSIG2 MITF KDF1 FHIP1A	9.60e-05	192	106	5	c15841f35e24d6ef6ce2a9a6dc62e66efdc3d9d5
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	SASH1 PDGFRB KLHL29 CLMN KIRREL1	9.60e-05	192	106	5	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PCLO CLMN MITF ATP1A1 FHIP1A	1.01e-04	194	106	5	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	facs-Brain_Non-Myeloid-Cortex\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSL6 KIAA0930 FAM171B CLMN PREX1	1.06e-04	196	106	5	256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCLO RAP1GAP2 MITF ATP1A1 FHIP1A	1.06e-04	196	106	5	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 SASH1 ARHGAP31 STARD9 PREX1	1.08e-04	197	106	5	0f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 ARHGAP31 STARD9 OSBPL5 PREX1	1.08e-04	197	106	5	412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	HSPG2 UNC5B ARHGAP31 STARD9 PREX1	1.11e-04	198	106	5	8689090bce9ab6e8f122426a404037e572c6713b
ToppCell	mLN-T_cell-cycling_gd_T\|T_cell / Region, Cell class and subclass	PIK3AP1 PCLO HJURP CDCA2 OSBPL5	1.14e-04	199	106	5	c81a194f8c2f120c6c4d74857912865a3c2fe1e7
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SFTA3 TACC2 MEGF9 MICAL2 FHIP1A	1.14e-04	199	106	5	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	medial-2-Epithelial-Alveolar_Epithelial_Type_1\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HSPG2 SFTA3 VSIG2 TACC2 MICAL2	1.14e-04	199	106	5	456460c761e26ed4b1d88d9bee4d2a7c9bd9d416
ToppCell	medial-Epithelial-Alveolar_Epithelial_Type_1-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HSPG2 SFTA3 VSIG2 TACC2 MICAL2	1.14e-04	199	106	5	5263338242f95c04690d0795749ccc20b0d19f7a
ToppCell	medial-Epithelial-Alveolar_Epithelial_Type_1\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HSPG2 SFTA3 VSIG2 TACC2 MICAL2	1.14e-04	199	106	5	c11365653c69a5dfb37946231f8af05149a61a71
Disease	Waardenburg syndrome type 1 (implicated_via_orthology)	MITF PAX3	1.21e-05	2	103	2	DOID:0110948 (implicated_via_orthology)
Disease	Waardenburg syndrome (is_implicated_in)	MITF PAX3	1.20e-04	5	103	2	DOID:9258 (is_implicated_in)
Disease	Waardenburg Syndrome	MITF PAX3	1.79e-04	6	103	2	C3266898
Disease	familial hemiplegic migraine (implicated_via_orthology)	ATP1A1 ATP1A3	2.51e-04	7	103	2	DOID:0060178 (implicated_via_orthology)
Disease	central serous retinopathy	RBBP8NL PREX1	3.33e-04	8	103	2	EFO_0009784
Disease	chronic central serous retinopathy	RBBP8NL MEGF9	4.28e-04	9	103	2	EFO_0009363
Disease	multiple myeloma	UNC5B DIDO1 FNDC3A PREX1	6.51e-04	112	103	4	EFO_0001378
Disease	nervous system disease (implicated_via_orthology)	ATP1A1 ATP1A3	7.78e-04	12	103	2	DOID:863 (implicated_via_orthology)
Disease	abdominal adipose tissue measurement	CDCA2 ATP1A1 ATP1A3	8.52e-04	53	103	3	EFO_0803316
Disease	DEAFNESS, AUTOSOMAL RECESSIVE (disorder)	TRIOBP PTPRQ	9.18e-04	13	103	2	C1846647
Disease	lysosomal storage disease (implicated_via_orthology)	TFEB MITF	1.40e-03	16	103	2	DOID:3211 (implicated_via_orthology)
Disease	Hereditary hearing loss and deafness	TRIOBP PTPRQ MITF PAX3	1.74e-03	146	103	4	cv:C0236038
Disease	cerebral microbleeds	HSPG2 OSBPL5	1.99e-03	19	103	2	EFO_0010059
Disease	monocyte count	PIK3AP1 PDGFRB SERTAD2 RAP1GAP2 CCDC175 DIDO1 LPA KIRREL1 ATP1A1 ATP1A3 PREX1 CBX8	2.19e-03	1320	103	12	EFO_0005091
Disease	Deaf Mutism	MITF PAX3	2.20e-03	20	103	2	C4082305
Disease	Deafness, Acquired	MITF PAX3	2.20e-03	20	103	2	C0751068
Disease	Hearing Loss, Extreme	MITF PAX3	2.20e-03	20	103	2	C0086395
Disease	Complete Hearing Loss	MITF PAX3	2.20e-03	20	103	2	C0581883
Disease	Bilateral Deafness	MITF PAX3	2.20e-03	20	103	2	C3665473
Disease	Prelingual Deafness	MITF PAX3	2.20e-03	20	103	2	C0011052
Disease	nicotine dependence symptom count, depressive symptom measurement	PCLO KLHL29 PREX1	2.32e-03	75	103	3	EFO_0007006, EFO_0009262
Disease	Coronary heart disease	ESR2 LPA	3.17e-03	24	103	2	C0010068
Disease	HDL cholesterol change measurement	ESR2 FNDC3A	3.17e-03	24	103	2	EFO_0007805
Disease	nephrotic syndrome (implicated_via_orthology)	GAPVD1 KIRREL1	3.17e-03	24	103	2	DOID:1184 (implicated_via_orthology)
Disease	orofacial cleft, sex interaction measurement	SFTA3 OSBPL5 SCN10A	3.43e-03	86	103	3	EFO_0008343, MONDO_0000358
Disease	inflammatory bowel disease (implicated_via_orthology)	ESR2 MUC2	3.44e-03	25	103	2	DOID:0050589 (implicated_via_orthology)
Disease	Deafness	MITF PAX3	3.44e-03	25	103	2	C0011053

Protein segments in the cluster

Peptide	Gene	Start	Entry
SSQGSLCISGTEEPE	ANKRD10	321	Q9NXR5
DTSEPCVLETLGGSS	BLACE	116	A4D250
ISEDSGCDSVTDTEP	PIK3AP1	141	Q6ZUJ8
GLSVSDETCLSTSEP	DISP2	1291	A7MBM2
SGSTEPCAQLSISSI	DDTL	51	A6NHG4
ASTSVESLLSICPEA	ASTE1	586	Q2TB18
LSIDESSLTGETTPC	ATP2C1	181	P98194
CTVTSASPLEEATLS	ATP5PO	141	P48047
VDGTLCSPDSTSVCV	ADAMTS15	636	Q8TE58
AKSTPSTCESSTGVD	ANKRD6	526	Q9Y2G4
LGSTAIEAPSSTCVA	HJURP	651	Q8NCD3
GTTEPTTSSSLCGID	RBFA	226	Q8N0V3
CEEGVTVTTPSLSGA	HSPG2	3921	P98160
SLTSSISEDCLPGTV	PCDHGA5	351	Q9Y5G8
TPSCEITFIESEEGS	GCK	431	P35557
TSLSSESVSCPQGSL	CDC42BPG	1511	Q6DT37
SSVSNTEEVPGSLCL	RAD9B	356	Q6WBX8
VVPCADDSQISSSSG	ANKRD31	1661	Q8N7Z5
LVTSATNGDVPCSDT	KIDINS220	856	Q9ULH0
APSATLVSLSSVSDC	MAP3K10	741	Q02779
SITGSECSPAEDSKS	ESR2	506	Q92731
TESLVLTVPCGSDST	GPAA1	141	O43292
LEAVETLGSTSTICS	ATP1A1	361	P05023
SVLLDPCTGSTISET	GAPVD1	696	Q14C86
VSTGDTSPCGTEEDS	KIAA0930	261	Q6ICG6
LFPEGSVCSDVSSSI	FAM199X	111	Q6PEV8
VCTTDSSSPITTLDS	PCLO	2191	Q9Y6V0
TNTTSDDCILPSGEI	MUC2	4626	Q02817
STCPTGPDSESVLSV	NEK5	676	Q6P3R8
SGSTEPCAQLSISSI	DDT	51	P30046
PESCSSVAESNGVLT	KDM4C	511	Q9H3R0
STGSCSIKSSELEPE	MEGF9	356	Q9H1U4
ETECQTTTEEGSSPT	MON2	511	Q7Z3U7
EQESSCDTVDGSPTS	HIPK3	941	Q9H422
TAVSTSGPEDICSSS	GORASP1	336	Q9BQQ3
TSPILALSCTDTDNT	OR8H3	181	Q8N146
PELSCCDSSTISFIT	PTPRO	616	Q16827
EGDESTCHVSTLPET	PTPRQ	1456	Q9UMZ3
TGGLEPTTTVSASCS	PAX3	416	P23760
CGLDTTSTELSVVES	EIF6	206	P56537
EGTTVLLTSCSSEAL	PARP14	571	Q460N5
ATTSTTGEGPECICT	RBBP8NL	591	Q8NC74
ISTSSVEDCEGPVSS	BOD1L1	2256	Q8NFC6
LLSSCSGTTTPTVEE	FHIP1A	146	Q05DH4
LQSLTEEGSVSSACP	FHIP1A	536	Q05DH4
SDLVQCGVTSPSSAE	CBX8	256	Q9HC52
CTLPSTLGSSVAVEA	CCDC175	31	P0C221
GTPSEAEIFTTLSCE	FNDC3A	356	Q9Y2H6
VVCDSSPSADGAVTS	CBLN2	66	Q8IUK8
SCPATDAETASEGSV	DIDO1	101	Q9BTC0
SPEDLSVICFTSGTT	ACSL5	251	Q9ULC5
LTQCSETESGVLETP	LPA	1576	P08519
STASECPSLLSTTAE	IFRD2	106	Q12894
AGTDSPVSCASVTEE	CDCA2	706	Q69YH5
PSEISGTSSSGCALE	CEP192	996	Q8TEP8
LEAVETLGSTSTICS	ATP1A3	351	P13637
PTTTDIGSDVTLTCV	KIRREL1	316	Q96J84
GSTSTGVESILEPCD	FAM102B	241	Q5T8I3
SETECPDGLLCTSTI	DCLRE1A	151	Q6PJP8
TTGITLTTDCLEDSL	CGRRF1	81	Q99675
SAAATLEPSIISDTC	DIRC1	51	Q969H9
LDLSSSESGTTVCSP	FAM171B	741	Q6P995
EPSVSLSTSEGCEDA	C14orf178	106	Q8N769
DTPTESSCAVAAIGT	MICAL2	1091	O94851
EVNTSSTISCDSPLE	PDGFRB	1051	P09619
ESSGSTPESCPELSD	OSBPL5	776	Q9H0X9
PVSETCTDRSGISTG	FUT8	261	Q9BYC5
TASLVGVTSSSCPAD	TFEB	201	P19484
GTPTSLGSSICEEEE	RAP1GAP2	121	Q684P5
TITEPTSGGSCDASL	PREX1	1106	Q8TCU6
SVDGSPTTAFTVLEC	SHKBP1	536	Q8TBC3
LTESSTCEPSTVAAV	STARD9	3036	Q9P2P6
PCLSTEDSTEGTAEA	KDF1	111	Q8NAX2
SSLLSSGVDCGTEET	SNPH	261	O15079
DCVVLTSSPEATETS	NFATC2IP	331	Q8NCF5
PATSSCESVLTELSA	STARD8	61	Q92502
EDPLSASTSGCQSVV	TRIOBP	61	Q9H2D6
TISEDSIEVLSTCPS	SMCR8	511	Q8TEV9
SQGASCSLVSTPEEI	STRA8	231	Q7Z7C7
QPDDLSIVCFTSGTT	ACSL6	266	Q9UKU0
PSSCVSLETLGSHSE	CLMN	691	Q96JQ2
PSTSCLSQLESGSIA	C11orf53	131	Q8IXP5
ELDSISTCPNETVSL	USP53	1021	Q70EK8
TPTESLASLCTTQSE	TRAK2	526	O60296
TVDTDALTPSSTLCE	ZXDB	731	P98169
ALTPSSTLCENSVSE	ZXDB	736	P98169
ALESQSPGCTTLLST	USP19	881	O94966
CFSTTTSGPQDLVTE	SLC16A13	396	Q7RTY0
DLTCTTTLDLTDGTI	MITF	441	O75030
IEELCPTSTSTEAAT	SERTAD2	176	Q14140
TSSSEGSTVDCLDPE	SCN10A	1081	Q9Y5Y9
SSLSESLPVQCTDGS	ZFAND6	56	Q6FIF0
TCESTKTTLPLGTEE	ZBTB44	271	Q8NCP5
IEESLGFCSAVSTPE	SASH1	111	O94885
TPCSGSSFEETEALV	TACC2	2571	O95359
SSETSVTELGPSCSQ	TECPR2	766	O15040
TLEVPSSSSCANLET	ARHGAP31	966	Q2M1Z3
IVITSTATCPESSEE	ZNF518A	1206	Q6AHZ1
LDTLCSAPGSTVTTQ	UNC5B	836	Q8IZJ1
SPCVSVLLDSSTDAS	ZNF862	621	O60290
AETLAVSSGCPATSV	ZNF445	331	P59923
DTLTPSSTLCENSVS	ZXDA	731	P98168
CTVPDDVLASDITSA	ZFX	111	P17010
LSGFENPVSESTTLC	SFTA3	31	P0C7M3
GPELCSVSLTSEISD	TCHHL1	831	Q5QJ38
SCSSGESIEPITAFQ	MID2	61	Q9UJV3
SDSEEVSSESGCSTP	TRIM66	1161	O15016
ECSSLSAVSPSESVA	TTLL4	536	Q14679
ASCELTLSVTEPSQG	VSIG2	226	Q96IQ7
SSSAEDTLSCPVTEV	WNK3	1146	Q9BYP7
APCTTGSSEAITSLV	KLHL29	71	Q96CT2