Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncoumarin 7-hydroxylase activity

CYP2A6 CYP2A7 CYP2A13

3.95e-083693GO:0008389
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP2A6 CYP2A7 CYP2A13

7.59e-0524693GO:0008392
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP2A6 CYP2A7 CYP2A13

1.09e-0427693GO:0008391
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor binding

APOA5 APBB3 MMP13

2.19e-0434693GO:0050750
GeneOntologyMolecularFunctionsteroid hydroxylase activity

CYP2A6 CYP2A7 CYP2A13

2.19e-0434693GO:0008395
GeneOntologyMolecularFunctionaromatase activity

CYP2A6 CYP2A7 CYP2A13

2.39e-0435693GO:0070330
GeneOntologyMolecularFunctionsodium channel inhibitor activity

NEDD4L NEDD4

3.25e-048692GO:0019871
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

APOA5 APBB3 MMP13

3.30e-0439693GO:0070325
GeneOntologyMolecularFunctiontransporter activity

XKR9 SLC25A5 APOA5 TRPM7 SLC22A11 SLC13A3 SERINC5 PKD1L2 ATP1B1 TMC3 NDUFV1 SLC27A4 ABCB4

4.14e-0412896913GO:0005215
GeneOntologyMolecularFunctionlipid transporter activity

XKR9 APOA5 SLC22A11 SLC27A4 ABCB4

5.85e-04196695GO:0005319
GeneOntologyMolecularFunctionlysozyme activity

LYZL2 LYZL1

6.34e-0411692GO:0003796
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP2A6 CYP2A7 CYP2A13

6.49e-0449693GO:0016712
GeneOntologyMolecularFunctionpeptidoglycan muralytic activity

LYZL2 LYZL1

1.20e-0315692GO:0061783
GeneOntologyMolecularFunctionquinone binding

AOC1 SQOR

1.55e-0317692GO:0048038
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC25A5 TRPM7 SLC22A11 SLC13A3 SERINC5 PKD1L2 ATP1B1 TMC3 NDUFV1 SLC27A4 ABCB4

2.27e-0311806911GO:0022857
GeneOntologyMolecularFunctioniron ion binding

CYP2A6 CYP2A7 CYP2A13 SC5D

2.62e-03166694GO:0005506
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC25A5 SLC22A11 SLC13A3 SERINC5 SLC27A4

3.44e-03293695GO:0008514
GeneOntologyMolecularFunctionfatty acid ligase activity

ACSM4 SLC27A4

3.63e-0326692GO:0015645
GeneOntologyMolecularFunctionCoA-ligase activity

ACSM4 SLC27A4

3.91e-0327692GO:0016405
GeneOntologyBiologicalProcessphenylpropanoid metabolic process

CYP2A6 CYP2A7 CYP2A13

3.87e-0610673GO:0009698
GeneOntologyBiologicalProcesscoumarin metabolic process

CYP2A6 CYP2A7 CYP2A13

3.87e-0610673GO:0009804
GeneOntologyBiologicalProcessepoxygenase P450 pathway

CYP2A6 CYP2A7 CYP2A13

4.83e-0522673GO:0019373
MousePhenodecreased intestinal cholesterol absorption

CYP2A6 CYP2A7 CYP2A13 ABCB4

4.22e-0717534MP:0002647
MousePhenoabnormal intestinal cholesterol absorption

CYP2A6 CYP2A7 CYP2A13 ABCB4

6.84e-0719534MP:0002645
MousePhenoabnormal digestion

CYP2A6 CYP2A7 CYP2A13 FOXQ1 TRPM7 ABCB4

2.68e-06105536MP:0001664
MousePhenoabnormal intestinal lipid absorption

CYP2A6 CYP2A7 CYP2A13 ABCB4

5.37e-0631534MP:0005342
MousePhenoabnormal bile salt homeostasis

CYP2A6 CYP2A7 CYP2A13 ABCB4

2.91e-0547534MP:0005365
MousePhenoabnormal intestinal absorption

CYP2A6 CYP2A7 CYP2A13 ABCB4

7.18e-0559534MP:0001666
MousePhenoshiny fur

FOXQ1 TMEM79

2.10e-046532MP:0000411
MousePhenoabnormal hair cortex morphology

FOXQ1 TMEM79

2.93e-047532MP:0003811
DomainFibrinogen_a/b/g_C_2

MFAP4 FCN2 FIBCD1 ANGPTL7 FGL2

2.57e-0824705IPR014715
Domain-

MFAP4 FCN2 FIBCD1 ANGPTL7 FGL2

2.57e-08247054.10.530.10
DomainFibrinogen_C

MFAP4 FCN2 FIBCD1 ANGPTL7 FGL2

4.84e-0827705PF00147
DomainFBG

MFAP4 FCN2 FIBCD1 ANGPTL7 FGL2

7.08e-0829705SM00186
Domain-

MFAP4 FCN2 FIBCD1 ANGPTL7 FGL2

8.47e-08307053.90.215.10
DomainFibrinogen_a/b/g_C_1

MFAP4 FCN2 FIBCD1 ANGPTL7 FGL2

8.47e-0830705IPR014716
DomainFIBRINOGEN_C_1

MFAP4 FCN2 FIBCD1 ANGPTL7 FGL2

1.19e-0732705PS00514
DomainFibrinogen_a/b/g_C_dom

MFAP4 FCN2 FIBCD1 ANGPTL7 FGL2

1.19e-0732705IPR002181
DomainFIBRINOGEN_C_2

MFAP4 FCN2 FIBCD1 ANGPTL7 FGL2

1.19e-0732705PS51406
DomainCyt_P450_E_grp-I_CYP2A-like

CYP2A6 CYP2A7 CYP2A13

2.01e-074703IPR008067
DomainLYZL1/LYZL2

LYZL2 LYZL1

1.38e-052702IPR030057
DomainWW

NEDD4L APBB3 PLEKHA5 NEDD4

2.86e-0547704PF00397
DomainWW

NEDD4L APBB3 PLEKHA5 NEDD4

3.11e-0548704SM00456
DomainWW_DOMAIN_2

NEDD4L APBB3 PLEKHA5 NEDD4

3.96e-0551704PS50020
DomainWW_DOMAIN_1

NEDD4L APBB3 PLEKHA5 NEDD4

3.96e-0551704PS01159
DomainWW_dom

NEDD4L APBB3 PLEKHA5 NEDD4

4.28e-0552704IPR001202
DomainFibrinogen_CS

FCN2 FIBCD1 FGL2

4.68e-0519703IPR020837
DomainGlyco_hydro_22_lys

LYZL2 LYZL1

2.87e-047702IPR000974
DomainGlyco_hydro_22_CS

LYZL2 LYZL1

2.87e-047702IPR019799
DomainSH3_2

MIA3 SORBS2 MAP3K10 MIA

3.05e-0486704IPR011511
DomainSH3_2

MIA3 SORBS2 MAP3K10 MIA

3.05e-0486704PF07653
DomainGlyco_hydro_22

LYZL2 LYZL1

3.82e-048702IPR001916
DomainLACTALBUMIN_LYSOZYME_2

LYZL2 LYZL1

3.82e-048702PS51348
DomainLys

LYZL2 LYZL1

3.82e-048702PF00062
DomainLACTALBUMIN_LYSOZYME_1

LYZL2 LYZL1

3.82e-048702PS00128
DomainLYZ1

LYZL2 LYZL1

3.82e-048702SM00263
DomainLysozyme-like_dom

LYZL2 LYZL1

6.11e-0410702IPR023346
DomainCyt_P450_E_grp-I

CYP2A6 CYP2A7 CYP2A13

6.39e-0445703IPR002401
DomainCyt_P450_CS

CYP2A6 CYP2A7 CYP2A13

1.03e-0353703IPR017972
DomainCYTOCHROME_P450

CYP2A6 CYP2A7 CYP2A13

1.28e-0357703PS00086
DomainSH3

MIA3 SORBS2 MAP3K10 PLCG1 MIA

1.30e-03216705SM00326
DomainSH3

MIA3 SORBS2 MAP3K10 PLCG1 MIA

1.30e-03216705PS50002
Domain-

CYP2A6 CYP2A7 CYP2A13

1.34e-03587031.10.630.10
Domainp450

CYP2A6 CYP2A7 CYP2A13

1.34e-0358703PF00067
DomainSH3_domain

MIA3 SORBS2 MAP3K10 PLCG1 MIA

1.41e-03220705IPR001452
DomainPept_M10A_Zn_BS

MMP11 MMP13

1.41e-0315702IPR021158
DomainCyt_P450

CYP2A6 CYP2A7 CYP2A13

1.48e-0360703IPR001128
DomainHemopexin_CS

MMP11 MMP13

1.82e-0317702IPR018486
DomainAMP-bd_C

ACSM4 SLC27A4

1.82e-0317702IPR025110
DomainAMP-binding_C

ACSM4 SLC27A4

1.82e-0317702PF13193
DomainPept_M10A_stromelysin-type

MMP11 MMP13

2.04e-0318702IPR016293
Domainzf-MYND

ZMYND15 TDRD1

2.78e-0321702PF01753
DomainZnf_MYND

ZMYND15 TDRD1

3.05e-0322702IPR002893
DomainZF_MYND_1

ZMYND15 TDRD1

3.05e-0322702PS01360
DomainZF_MYND_2

ZMYND15 TDRD1

3.05e-0322702PS50865
DomainHemopexin-like_dom

MMP11 MMP13

3.33e-0323702IPR000585
DomainAcetyltransf_1

NAT10 KAT14

3.33e-0323702PF00583
DomainHemopexin-like_repeat

MMP11 MMP13

3.33e-0323702IPR018487
DomainM10A_MMP

MMP11 MMP13

3.33e-0323702IPR033739
DomainHemopexin

MMP11 MMP13

3.33e-0323702PF00045
DomainHEMOPEXIN

MMP11 MMP13

3.33e-0323702PS00024
Domain-

MMP11 MMP13

3.33e-03237022.110.10.10
DomainHEMOPEXIN_2

MMP11 MMP13

3.33e-0323702PS51642
DomainHX

MMP11 MMP13

3.33e-0323702SM00120
DomainPept_M10A

MMP11 MMP13

3.33e-0323702IPR021190
DomainPeptidase_M10

MMP11 MMP13

3.62e-0324702PF00413
PathwayREACTOME_CYP2E1_REACTIONS

CYP2A6 CYP2A7 CYP2A13

6.00e-0611483M27130
PathwayREACTOME_CYP2E1_REACTIONS

CYP2A6 CYP2A7 CYP2A13

7.98e-0612483MM14847
PathwayREACTOME_FATTY_ACIDS

CYP2A6 CYP2A7 CYP2A13

2.92e-0518483MM14841
PathwayREACTOME_XENOBIOTICS

CYP2A6 CYP2A7 CYP2A13

6.25e-0523483M5372
PathwayREACTOME_XENOBIOTICS

CYP2A6 CYP2A7 CYP2A13

8.08e-0525483MM14846
PathwayKEGG_MEDICUS_ENV_FACTOR_NNK_TO_DNA_ADDUCTS

CYP2A6 CYP2A13

1.13e-045482M47808
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

NEDD4L SLC25A5 APOA5 TRPM7 SLC22A11 PRKACG SLC13A3 ATP1B1 SLC27A4 ABCB4

1.52e-047364810M27287
PathwayREACTOME_RET_SIGNALING

PRKACG DOK2 PLCG1

3.35e-0440483M27746
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP2A6 CYP2A7 CYP2A13 AOC1

4.24e-04104484M738
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP2A6 CYP2A7 CYP2A13 AOC1

4.40e-04105484MM14842
Pubmed

Regulation of bile acid metabolism in mouse models with hydrophobic bile acid composition.

CYP2A6 CYP2A7 CYP2A13

7.81e-09370331645370
Pubmed

Reciprocal regulation of sex-dependent expression of testosterone 15 alpha-hydroxylase (P-450(15 alpha)) in liver and kidney of male mice by androgen. Evidence for a single gene.

CYP2A6 CYP2A7 CYP2A13

7.81e-0937033346244
Pubmed

Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue.

CYP2A6 CYP2A7 CYP2A13

7.81e-0937032733794
Pubmed

A trans-acting locus regulates transcriptional repression of the female-specific steroid 15 alpha-hydroxylase gene in male mice.

CYP2A6 CYP2A7 CYP2A13

7.81e-0937038297477
Pubmed

Lack of the steroid 15 alpha-hydroxylase gene (Cyp2a-4) in wild mouse strain Mus spretus: rapid evolution of the P450 gene superfamily.

CYP2A6 CYP2A7 CYP2A13

7.81e-0937038188299
Pubmed

Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction.

CYP2A6 CYP2A7 CYP2A13

7.81e-0937038484736
Pubmed

Comparison of hamster and mouse reveals interspecies differences in the regulation of hepatic CYP2A isozymes.

CYP2A6 CYP2A7 CYP2A13

7.81e-0937038250953
Pubmed

The structure and characterization of type I P-450(15) alpha gene as major steroid 15 alpha-hydroxylase and its comparison with type II P-450(15) alpha gene.

CYP2A6 CYP2A7 CYP2A13

7.81e-0937032703500
Pubmed

Cerium-induced strain-dependent increase in Cyp2a-4/5 (cytochrome P4502a-4/5) expression in the liver and kidneys of inbred mice.

CYP2A6 CYP2A7 CYP2A13

7.81e-0937031417950
Pubmed

Impact of nicotine metabolism on nicotine's pharmacological effects and behavioral responses: insights from a Cyp2a(4/5)bgs-null mouse.

CYP2A6 CYP2A7 CYP2A13

7.81e-09370324045421
Pubmed

Highly homologous mouse Cyp2a4 and Cyp2a5 genes are differentially expressed in the liver and both express long non-coding antisense RNAs.

CYP2A6 CYP2A7 CYP2A13

7.81e-09370332987105
Pubmed

Alteration of the substrate specificity of mouse 2A P450s by the identity of residue-209: steroid-binding site and orientation.

CYP2A6 CYP2A7 CYP2A13

7.81e-09370322217847
Pubmed

Mouse steroid 15 alpha-hydroxylase gene family: identification of type II P-450(15)alpha as coumarin 7-hydroxylase.

CYP2A6 CYP2A7 CYP2A13

7.81e-0937032765478
Pubmed

Sexual dimorphism of testosterone 15 alpha-hydroxylase mRNA levels in mouse liver. cDNA cloning and regulation.

CYP2A6 CYP2A7 CYP2A13

7.81e-0937032415518
Pubmed

Differential distribution of CYP2A6 and CYP2A13 in the human respiratory tract.

CYP2A6 CYP2A7 CYP2A13

7.81e-09370322890016
Pubmed

Transcriptional regulation by HNF-4 of the steroid 15alpha-hydroxylase P450 (Cyp2a-4) gene in mouse liver.

CYP2A6 CYP2A7 CYP2A13

3.12e-0847039408084
Pubmed

Circadian expression of the steroid 15 alpha-hydroxylase (Cyp2a4) and coumarin 7-hydroxylase (Cyp2a5) genes in mouse liver is regulated by the PAR leucine zipper transcription factor DBP.

CYP2A6 CYP2A7 CYP2A13

3.12e-08470310490589
Pubmed

Two steroid 15 alpha-hydroxylase genes and a homologous gene family in mice.

CYP2A6 CYP2A7 CYP2A13

3.12e-0847031970547
Pubmed

A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP.

CYP2A6 CYP2A7 CYP2A13

3.12e-0847037565685
Pubmed

A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles.

CYP2A6 CYP2A7 CYP2A13

1.55e-0767037668294
Pubmed

Organization and evolution of the cytochrome P450 CYP2A-2B-2F subfamily gene cluster on human chromosome 19.

CYP2A6 CYP2A7 CYP2A13

1.55e-0767038587134
Pubmed

Organization and evolution of the Cyp2 gene cluster on mouse chromosome 7, and comparison with the syntenic human cluster.

CYP2A6 CYP2A7 CYP2A13

2.72e-07770314630516
Pubmed

Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses.

CYP2A6 CYP2A7 CYP2A13

2.72e-0777039630227
Pubmed

Genes encoding alpha and beta subunits of Na,K-ATPase are located on three different chromosomes in the mouse.

CYP2A6 CYP2A13 ATP1B1

4.34e-0787032885848
Pubmed

Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder.

CYP2A6 CYP2A7 CYP2A13

6.50e-07970337838304
Pubmed

Establishment and analysis of a mouse model that regulates sex-related differences in liver drug metabolism.

CYP2A6 CYP2A7 CYP2A13

3.49e-061570329968852
Pubmed

Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity.

CYP2A6 CYP2A7

3.99e-06270212325023
Pubmed

The mechanistic links between insulin and human organic anion transporter 4.

NEDD4L SLC22A11

3.99e-06270230453017
Pubmed

Distinct characteristics of two human Nedd4 proteins with respect to epithelial Na(+) channel regulation.

NEDD4L NEDD4

3.99e-06270211502596
Pubmed

Evaluation of inhibition selectivity for human cytochrome P450 2A enzymes.

CYP2A6 CYP2A13

3.99e-06270222696418
Pubmed

Suppressed hepatocyte proliferation via a ROS-HNE-P21 pathway is associated with nicotine- and cotinine-enhanced alcoholic fatty liver in mice.

CYP2A6 CYP2A13

3.99e-06270230876690
Pubmed

CYP2A5 induction and hepatocellular stress: an adaptive response to perturbations of heme homeostasis.

CYP2A6 CYP2A13

3.99e-06270221395539
Pubmed

Species differences in coumarin metabolism: a molecular modelling evaluation of CYP2A interactions.

CYP2A6 CYP2A13

3.99e-06270212162851
Pubmed

Molecular characterization of the murine Coh locus: an amino acid difference at position 117 confers high and low coumarin 7-hydroxylase activity in P450coh.

CYP2A6 CYP2A13

3.99e-0627021302041
Pubmed

Structural alteration of mouse P450coh by mutation of glycine-207 to proline: spin equilibrium, enzyme kinetics, and heat sensitivity.

CYP2A6 CYP2A13

3.99e-0627028395817
Pubmed

Absence of cytochrome P450 2A5 enhances alcohol-induced liver injury in mice.

CYP2A6 CYP2A13

3.99e-06270225804444
Pubmed

Effect of pyrazole, cobalt and phenobarbital on mouse liver cytochrome P-450 2a-4/5 (Cyp2a-4/5) expression.

CYP2A6 CYP2A13

3.99e-0627021520280
Pubmed

Role of CYP2A13 in the bioactivation and lung tumorigenicity of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: in vivo studies using a CYP2A13-humanized mouse model.

CYP2A6 CYP2A13

3.99e-06270223917075
Pubmed

Nedd4 and Nedd4-2: ubiquitin ligases at work in the neuron.

NEDD4L NEDD4

3.99e-06270223262292
Pubmed

Nicotine enhances alcoholic fatty liver in mice: Role of CYP2A5.

CYP2A6 CYP2A13

3.99e-06270230222954
Pubmed

CYP2A7 polymorphic alleles confound the genotyping of CYP2A6*4A allele.

CYP2A6 CYP2A7

3.99e-06270216636685
Pubmed

Up-regulation of CYP2A5 expression by porphyrinogenic agents in mouse liver.

CYP2A6 CYP2A13

3.99e-0627027543189
Pubmed

Genomic Landscape of Experimental Bladder Cancer in Rodents and Its Application to Human Bladder Cancer: Gene Amplification and Potential Overexpression of Cyp2a5/CYP2A6 Are Associated with the Invasive Phenotype.

CYP2A6 CYP2A13

3.99e-06270227902773
Pubmed

Effect of the expression of matrix metalloproteases and their tissue inhibitors on survival of patients with resectable colorectal cancer.

MMP11 MMP13

3.99e-06270222488635
Pubmed

Down-regulating destruction: phosphorylation regulates the E3 ubiquitin ligase Nedd4-2.

NEDD4L NEDD4

3.99e-06270219602703
Pubmed

Characterization and regulation of sex-specific mouse steroid hydroxylase genes.

CYP2A6 CYP2A13

3.99e-0627022372744
Pubmed

A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel.

NEDD4L NEDD4

3.99e-06270211149908
Pubmed

The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes.

CYP2A6 CYP2A7

3.99e-0627022322567
Pubmed

Metabolic effects of CYP2A6 and CYP2A13 on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced gene mutation--a mammalian cell-based mutagenesis approach.

CYP2A6 CYP2A13

3.99e-06270221473878
Pubmed

Dietary sodium modulates nephropathy in Nedd4-2-deficient mice.

NEDD4L NEDD4

3.99e-06270231802037
Pubmed

The CYP2A gene subfamily: species differences, regulation, catalytic activities and role in chemical carcinogenesis.

CYP2A6 CYP2A13

3.99e-0627027581481
Pubmed

Circadian Regulation of Hepatic Cytochrome P450 2a5 by Peroxisome Proliferator-Activated Receptor γ.

CYP2A6 CYP2A13

3.99e-06270230154104
Pubmed

Expression of CYP2A genes in human liver and extrahepatic tissues.

CYP2A7 CYP2A13

3.99e-06270210353262
Pubmed

Expression and alternative splicing of the cytochrome P-450 CYP2A7.

CYP2A6 CYP2A7

3.99e-0627027864805
Pubmed

Interstrain differences in the expression and activity of Cyp2a5 in the mouse liver.

CYP2A6 CYP2A13

3.99e-06270228298240
Pubmed

Genetic polymorphisms for a phenobarbital-inducible cytochrome P-450 map to the Coh locus in mice.

CYP2A6 CYP2A13

3.99e-0627026309775
Pubmed

Mechanism-based inhibition of cytochrome P450 (CYP)2A6 by chalepensin in recombinant systems, in human liver microsomes and in mice in vivo.

CYP2A6 CYP2A13

3.99e-06270221418183
Pubmed

Role of CYP2A5 in the bioactivation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice.

CYP2A6 CYP2A13

3.99e-06270222262919
Pubmed

Modulation of cytochrome P450 2A5 activity by lipopolysaccharide: low-dose effects and non-monotonic dose-response relationship.

CYP2A6 CYP2A13

3.99e-06270225635819
Pubmed

Genetic variation between mice in their metabolism of coumarin and its derivatives.

CYP2A6 CYP2A13

3.99e-062702566237
Pubmed

Role of CYP2A5 in the clearance of nicotine and cotinine: insights from studies on a Cyp2a5-null mouse model.

CYP2A6 CYP2A13

3.99e-06270219923441
Pubmed

MIA/CD-RAP Regulates MMP13 and Is a Potential New Disease-Modifying Target for Osteoarthritis Therapy.

MMP13 MIA

3.99e-06270236672165
Pubmed

Effects of lipopolysaccharide-stimulated inflammation and pyrazole-mediated hepatocellular injury on mouse hepatic Cyp2a5 expression.

CYP2A6 CYP2A13

3.99e-06270212499123
Pubmed

Physiological Functions of the Ubiquitin Ligases Nedd4-1 and Nedd4-2.

NEDD4L NEDD4

3.99e-06270237962894
Pubmed

Identification and characterization of a 44 kDa protein that binds specifically to the 3'-untranslated region of CYP2a5 mRNA: inducibility, subcellular distribution and possible role in mRNA stabilization.

CYP2A6 CYP2A13

3.99e-0627028611142
Pubmed

Function and regulation of the Cyp2a5/CYP2A6 genes in response to toxic insults in the liver.

CYP2A6 CYP2A13

3.99e-06270222497566
Pubmed

Coumarin toxicity in different strains of mice.

CYP2A6 CYP2A13

3.99e-062702665441
Pubmed

Essential role of the cytochrome P450 enzyme CYP2A5 in olfactory mucosal toxicity of naphthalene.

CYP2A6 CYP2A13

3.99e-06270224104196
Pubmed

The role of CYP2A5 in liver injury and fibrosis: chemical-specific difference.

CYP2A6 CYP2A13

3.99e-06270226363552
Pubmed

Mouse liver P450Coh: genetic regulation of the pyrazole-inducible enzyme and comparison with other P450 isoenzymes.

CYP2A6 CYP2A13

3.99e-0627022712571
Pubmed

Mass spectrometry analyses of normal and polyglutamine expanded ataxin-3 reveal novel interaction partners involved in mitochondrial function.

SLC25A5 UBAC2 SLC27A4 GNPAT

4.75e-065570429111377
Pubmed

Zinc Fingers and Homeoboxes 2 (Zhx2) Regulates Sexually Dimorphic Cyp Gene Expression in the Adult Mouse Liver.

CYP2A6 CYP2A7 CYP2A13

5.20e-061770327197076
Pubmed

Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS.

CYP2A6 CYP2A7 CYP2A13 SLC25A5

5.48e-065770417208939
Pubmed

Molecular genetics of the human cytochrome P450 monooxygenase superfamily.

CYP2A6 CYP2A7 CYP2A13

8.69e-06207039890157
Pubmed

Coactivator PGC-1alpha regulates the fasting inducible xenobiotic-metabolizing enzyme CYP2A5 in mouse primary hepatocytes.

CYP2A6 CYP2A13

1.20e-05370218602936
Pubmed

Regulation of Nedd4-2 self-ubiquitination and stability by a PY motif located within its HECT-domain.

NEDD4L NEDD4

1.20e-05370218498246
Pubmed

Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway.

NEDD4L NEDD4

1.20e-05370221852580
Pubmed

Expression of cytochrome P450 2A5 in a glucose-6-phosphate dehydrogenase-deficient mouse model of oxidative stress.

CYP2A6 CYP2A13

1.20e-05370218068688
Pubmed

CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism.

CYP2A6 CYP2A7

1.20e-05370211960914
Pubmed

Rip locus: regulation of female-specific isozyme (I-P-450(16 alpha) of testosterone 16 alpha-hydroxylase in mouse liver, chromosome localization, and cloning of P-450 cDNA.

CYP2A6 CYP2A13

1.20e-0537023219345
Pubmed

The high-affinity choline transporter CHT1 is regulated by the ubiquitin ligase Nedd4-2.

NEDD4L NEDD4

1.20e-05370222361880
Pubmed

Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination.

NEDD4L NEDD4

1.20e-05370215217910
Pubmed

Zfp30, a KRAB domain containing zinc finger protein gene, maps to mouse chromosome 7.

CYP2A6 CYP2A13

1.20e-0537027849402
Pubmed

Nedd4-2-mediated ubiquitination facilitates processing of surfactant protein-C.

NEDD4L NEDD4

1.20e-05370219423771
Pubmed

Mechanisms of olfactory toxicity of the herbicide 2,6-dichlorobenzonitrile: essential roles of CYP2A5 and target-tissue metabolic activation.

CYP2A6 CYP2A13

1.20e-05370220840855
Pubmed

Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway.

CYP2A6 CYP2A13

1.20e-05370222552773
Pubmed

Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein.

NEDD4L NEDD4

1.20e-05370212050153
Pubmed

Interaction of serum- and glucocorticoid regulated kinase 1 (SGK1) with the WW-domains of Nedd4-2 is required for epithelial sodium channel regulation.

NEDD4L NEDD4

1.20e-05370220730100
Pubmed

Limited heme synthesis in porphobilinogen deaminase-deficient mice impairs transcriptional activation of specific cytochrome P450 genes by phenobarbital.

CYP2A6 CYP2A13

1.20e-05370211106424
Pubmed

Nedd4-2 but not Nedd4-1 is critical for protein kinase C-regulated ubiquitination, expression, and transport activity of human organic anion transporter 1.

NEDD4L NEDD4

1.20e-05370226823285
Pubmed

Mutations in TNK2 in severe autosomal recessive infantile onset epilepsy.

NEDD4L NEDD4

1.20e-05370223686771
Pubmed

Regulation of CYP2A5 gene by the transcription factor nuclear factor (erythroid-derived 2)-like 2.

CYP2A6 CYP2A13

1.20e-05370217303623
Pubmed

Serum- and glucocorticoid-inducible kinase SGK2 regulates human organic anion transporters 4 via ubiquitin ligase Nedd4-2.

NEDD4L SLC22A11

1.20e-05370226740304
Pubmed

Alternative splicing determines the domain structure of WWP1, a Nedd4 family protein.

NEDD4L NEDD4

1.20e-05370211779188
Pubmed

Knockout of secretin receptor reduces biliary damage and liver fibrosis in Mdr2-/- mice by diminishing senescence of cholangiocytes.

SCTR ABCB4

1.20e-05370229977037
Pubmed

Close linkage of the cytochrome P450IIA gene subfamily (Cyp2a) to Cyp2b and Coh on mouse chromosome 7.

CYP2A6 CYP2A13

1.20e-0537021973143
Pubmed

Characterization of the interactions between Nedd4-2, ENaC, and sgk-1 using surface plasmon resonance.

NEDD4L NEDD4

1.20e-05370212729930
Pubmed

A novel defensive mechanism against acetaminophen toxicity in the mouse lateral nasal gland: role of CYP2A5-mediated regulation of testosterone homeostasis and salivary androgen-binding protein expression.

CYP2A6 CYP2A13

1.20e-05370221252290
Pubmed

Mitochondrial targeting of bilirubin regulatory enzymes: An adaptive response to oxidative stress.

CYP2A6 CYP2A13

1.20e-05370225478736
Pubmed

Aryl hydrocarbon receptor nuclear translocator and upstream stimulatory factor regulate Cytochrome P450 2a5 transcription through a common E-box site.

CYP2A6 CYP2A13

1.20e-05370217466327
InteractionCYP2A7 interactions

CYP2A6 CYP2A7 CYP2A13

3.67e-083683int:CYP2A7
InteractionDUSP9 interactions

AATK ARL10 NUP155 UBAC2 PLCG1

1.82e-0596685int:DUSP9
InteractionABL2 interactions

SORBS2 NEDD4L MAP3K10 SSTR3 NEDD4

3.07e-05107685int:ABL2
InteractionHS6ST2 interactions

LYZL2 MFAP4 TM2D3 LYZL1

3.30e-0554684int:HS6ST2
InteractionSCN9A interactions

NEDD4L SSTR3 NEDD4

4.68e-0521683int:SCN9A
InteractionEDEM3 interactions

LYZL2 MFAP4 NEDD4L TM2D3 ANGPTL7

4.71e-05117685int:EDEM3
Cytoband19q13.2

CYP2A6 CYP2A7 CYP2A13 MAP3K10 MIA

5.49e-0616470519q13.2
GeneFamilyFibrinogen C domain containing

MFAP4 FCN2 FIBCD1 ANGPTL7 FGL2

7.43e-0925515554
GeneFamilyMIA family

MIA3 MIA

2.34e-0535121300
GeneFamilyCytochrome P450 family 2

CYP2A6 CYP2A7 CYP2A13

1.30e-04355131001
GeneFamilyLysozymes, c-type

LYZL2 LYZL1

2.77e-0495121174
GeneFamilyRhomboid family

UBAC2 RHBDD3

6.95e-0414512926
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP11 MMP13

2.07e-0324512891
GeneFamilyGCN5 related N-acetyltransferases

NAT10 KAT14

2.07e-03245121134
GeneFamilyAcyl-CoA synthetase family

ACSM4 SLC27A4

2.43e-032651240
CoexpressionPRC2_SUZ12_UP.V1_UP

AATK FCN2 SCTR PLEKHA5 SLC13A3 DOK2

1.03e-05185706M2741
CoexpressionDURANTE_ADULT_OLFACTORY_NEUROEPITHELIUM_OLFACTORY_ENSHEATHING_GLIA

SORBS2 AATK METRN ANGPTL7 MIA

1.44e-05115705M39290
ToppCell5'-GW_trimst-2-LymphNode-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 AATK METRN ANGPTL7 FGL2 MIA

3.28e-07174706c9d4e375dedd2b099a9ed70ec38ff35bbb0ce48a
ToppCell5'-GW_trimst-2-LymphNode-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 AATK METRN ANGPTL7 FGL2 MIA

3.28e-071747061463c98f8f519dd030587abbdbeb1b4e1bca5dd1
ToppCell5'-GW_trimst-2-LymphNode-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 AATK METRN ANGPTL7 FGL2 MIA

3.28e-07174706d421c0069d24cb560a3a429929e3cd1eceaeabcf
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 AATK METRN ANGPTL7 FGL2 MIA

3.28e-07174706667035a11b68745fa8446d6c68214713be42710f
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXQ1 APOA5 ATP1B1 ENPEP ABCB4 NEDD4

3.39e-071757065c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 AATK METRN ANGPTL7 FGL2 MIA

4.00e-07180706b294f9db1e2ff51c94cde64fae4c2b057c0030a1
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 AATK METRN ANGPTL7 FGL2 MIA

4.85e-071867066f88b68735d0f7c9904eb8413e6007910d556185
ToppCellwk_08-11-Epithelial-PNS-intermediate_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SORBS2 AATK METRN ANGPTL7 FGL2 MIA

5.16e-071887063f3a744b2615bf72f6119f26087099110c0d21fc
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 AATK METRN ANGPTL7 FGL2 MIA

6.58e-07196706e6adcfe1a00d4910e0b92848f8a80224e0d6db12
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_NA|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SORBS2 NWD2 AATK TMC3 MIA

8.76e-061777058c78f7de091f16e86e326a73c9f1429e0232821f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NEDD4L SLC22A11 PLEKHA5 SLC13A3 ENPEP

1.11e-051867055784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS2 NEDD4L PLEKHA5 SLC13A3 ENPEP

1.27e-051917053c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS2 NEDD4L PLEKHA5 SLC13A3 ENPEP

1.27e-051917051c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 AATK METRN ANGPTL7 MIA

1.33e-051937053ea6b103e35bbb276e95301999618558fa3e38b1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NEDD4L PLEKHA5 SLC13A3 ATP1B1 ENPEP

1.33e-0519370582e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

SORBS2 NEDD4L PLEKHA5 SERINC5 TMEM117

1.33e-05193705503a979328c68b096680b71359a26f02fafdff35
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NEDD4L PLEKHA5 SLC13A3 ATP1B1 ENPEP

1.36e-051947057002937e8903e037332a215d00fbc7c7843b33f2
ToppCellBiopsy_Control_(H.)-Epithelial-SCGB3A2+_SCGB1A1+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

CYP2A6 CYP2A7 CYP2A13 FOXQ1 NEDD4L

1.51e-05198705a3d4b6e4259ded2193d94d2ff6d48cf67214fc35
ToppCelldistal-Epithelial-Club-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CYP2A6 FOXQ1 NEDD4L ATP1B1 MMP13

1.51e-0519870577c7fa7626ea35cb50de9c2f2df637d22e77d3fe
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SORBS2 FOXQ1 NEDD4L ATP1B1 MIA

1.54e-05199705ef1a0c278c23614fd6a3218a9733abe6ecd6f686
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SORBS2 FOXQ1 SEMA7A TM4SF18 ABCB4

1.54e-05199705d95d78b2ebc9a20532466e4d4be579b4faf6776f
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SORBS2 FOXQ1 SEMA7A TM4SF18 ABCB4

1.54e-05199705cdcfca94baba66e213cc3ffb0cfb4c75d6ab44ec
ToppCelldistal-Epithelial-Club|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CYP2A6 CYP2A7 FOXQ1 NEDD4L ATP1B1

1.54e-05199705c63ccce1285352927fd8c4f7374ec5fff8d70cec
ToppCelldistal-Epithelial-Club-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CYP2A6 CYP2A7 CYP2A13 NEDD4L ATP1B1

1.54e-05199705685cefbe6ff5db8b578e50b5849524ac2f347d0c
ToppCellHippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZMYND15 DOK2 MMP13 ANGPTL7

3.04e-05113704d5f183263cec9922d23cfd38ce9157eef4e58edb
ToppCellHippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZMYND15 DOK2 MMP13 ANGPTL7

3.04e-051137041df80af2c690dac6bfd3dfd7d0052b66c1ae6ea5
ToppCellHippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZMYND15 DOK2 MMP13 ANGPTL7

3.04e-05113704177414e4c859b047a4644664c596a3c22199cdf2
ToppCellHippocampus-Hematopoietic-MACROPHAGE-MP1(C1qb)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZMYND15 DOK2 MMP13 ANGPTL7

3.04e-051137044b5f545dc02364c5d96a02b0acd68faf1ec4192b
ToppCellHippocampus-Hematopoietic-MACROPHAGE|Hippocampus / BrainAtlas - Mouse McCarroll V32

ZMYND15 DOK2 MMP13 ANGPTL7

3.04e-05113704927d1071f0719b778f0c3d358c5f96a6ffac6645
ToppCelldroplet-Kidney-nan-3m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 PKD1L2 MMP13 FGL2

1.15e-04159704bea6e96ba40ebfc1e38687bfa1c61fe227c5a84d
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CYP2A6 CYP2A7 NEDD4L ATP1B1

1.23e-041627045c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCellfacs-BAT-Fat-3m-Lymphocytic-NK_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOK2 ATP1B1 DNMT1 FGL2

1.29e-04164704cbdb7e893cb3959b9920c0c7c535ace03a5f4986
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP2A6 SORBS2 METRN MIA

1.42e-04168704af82e07d1eec51fc6530155f37addbce6221885d
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

METRN DOK2 DNMT1 FGL2

1.45e-0416970420fbf78382fb0ba9a63ab1aa0abc615476994ac5
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MFAP4 SC5D MMP11 ENPEP

1.49e-04170704ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEDD4L SLC25A5 ATP1B1 TMEM117

1.49e-041707043229f2a02bfa075aa61118552d0407fc018ab3d1
ToppCelldroplet-Lung-nan-18m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 RHBDD3 DOK2 MMP13

1.52e-041717047ca404539344e14dcd90c746c9122f713a7db78b
ToppCelldroplet-Lung-nan-18m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 RHBDD3 DOK2 MMP13

1.52e-04171704ab113c8e773b0af47a87aed50e96be3ba71c3c82
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SORBS2 FIBCD1 TM4SF18 ABCB4

1.55e-04172704c3a99828838af3b85c8c885d69cc8018f55ced50
ToppCell10x5'-Lung-Myeloid_Dendritic-DC1|Lung / Manually curated celltypes from each tissue

SEMA7A PLEKHA5 SLC13A3 FGL2

1.55e-04172704243b8bb01cbec5c1bf8802cbf8a6153356b4c384
ToppCelldroplet-Lung-18m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZMYND15 RHBDD3 DOK2 MMP13

1.62e-0417470433e5903adb746f693433bdca11a75c508bbf50c0
ToppCelldroplet-Lung-18m-Hematologic-myeloid-interstitial_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZMYND15 RHBDD3 DOK2 MMP13

1.62e-04174704ca0c2f42544092848541863c4a47b334e6828b8a
ToppCellTCGA-Colorectal-Recurrent_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

CYP2A6 CYP2A7 APOA5 FCN2

1.66e-041757047f74961436f88c0e380819095e6104489914d765
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2A6 CYP2A7 LYZL1 ZBTB3

1.66e-0417570436cb3c8116bd467ee5da0630d8b3d3e4afcc2ded
ToppCellTCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

CYP2A6 CYP2A7 APOA5 FCN2

1.66e-04175704bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCell3'-Adult-Distal_Rectal-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

XKR9 ATP1B1 ULBP3 MIA

1.77e-04178704a95bb77a2c2ce7c38989e6f971812f7ee9f5bd4b
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2A6 CYP2A7 NEDD4L ATP1B1

1.77e-04178704f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

CYP2A6 CYP2A7 SORBS2 NEDD4L

1.77e-0417870435a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCellwk_08-11-Epithelial-PNS-Proliferating_Schwann|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

AATK METRN FGL2 MIA

1.81e-04179704ab23fee9adab1e63d5b5cd9faba6b9a92beef425
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-CLDN10+_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 FOXQ1 SCTR SERINC5

1.81e-041797047eca1e19ae6b5b1f18c721691dc3e860705628f2
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

XKR9 NIPSNAP3B ULBP3 ABCB4

1.81e-0417970487f608b137aae34572b150492a83a3a127cff40b
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 METRN ABCB4 MIA

1.89e-04181704a436e7e4c36403257ea90160a58ca0d6d7c0cdfc
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

CYP2A6 CYP2A7 NEDD4L ATP1B1

1.89e-04181704c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellwk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SORBS2 KAT14 NEDD4 MIA

1.93e-0418270400a148b1e499bf16325491536d187d4dd6b70c06
ToppCellwk_15-18-Epithelial-PNS-Late_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SORBS2 METRN ANGPTL7 MIA

1.93e-041827046462e0469224457e249d10e224082f727caa02d6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A11 PLEKHA5 SLC13A3 ENPEP

1.97e-04183704facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SORBS2 NEDD4L SCTR ATP1B1

1.97e-041837046847c1252d6bb105524f812658112517fd351eab
ToppCellPCW_13-14-Neuronal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SORBS2 NWD2 AATK MIA

2.01e-0418470465cf3460125e3dbc34978957bc138a449f71f7df
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 METRN ANGPTL7 MIA

2.01e-04184704226ccac00ac1c3a0ad7283785fd14312320e0ca6
ToppCellwk_20-22-Epithelial-PNS-intermediate_Schwann|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

AATK ANGPTL7 FGL2 MIA

2.01e-041847044e3ba64692868563a579902aa9c6f88cab5bce26
ToppCellControl-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

CYP2A6 CYP2A7 CYP2A13 NEDD4L

2.05e-041857046814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

SLC22A11 PLEKHA5 SLC13A3 ENPEP

2.14e-04187704d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCelldroplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

METRN DOK2 DNMT1 NEDD4

2.14e-0418770414c239af77116d28d511dea754b6150d20488080
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 METRN ANGPTL7 MIA

2.18e-04188704ccd2541892112a7a303f766adf9a7afeb754498c
ToppCelldroplet-Tongue-nan-24m-Epithelial-filiform|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXQ1 FIBCD1 PLEKHA5 SQOR

2.27e-0419070486ab845a7fae2111c0b01e1aec235e19c4c0ef5c
ToppCelldroplet-Heart-nan-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MFAP4 PLEKHA5 FGL2 NEDD4

2.27e-0419070496a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP2A7 CYP2A13 SORBS2 MIA

2.32e-04191704e96184aee03175fd9f1da11fa2b89d95ba58b817
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2A6 CYP2A7 SORBS2 NEDD4L

2.32e-0419170423776c7302cead3881b39127398f3b3e0d27885e
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

SORBS2 SEMA7A SLC25A5 MMP13

2.32e-0419170478ad7c555409ce1391bce406bc0f3ef575329ece
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MFAP4 MMP11 MMP13 ANGPTL7

2.36e-04192704f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AOC1 FOXQ1 ATP1B1 FGL2

2.36e-04192704967122c53af25b8f19a8411b4553d764c8d51c4d
ToppCell18-Distal-Epithelial-Secretory_progenitor|Distal / Age, Tissue, Lineage and Cell class

CYP2A6 CYP2A7 CYP2A13 NEDD4L

2.36e-041927049fae988ecd2ef1231bfd42a678a4903517694cbe
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MFAP4 MMP11 MMP13 ANGPTL7

2.36e-0419270441a8326cd5bc19ad5041068501bab4c72399222e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEDD4L PLEKHA5 SLC13A3 ATP1B1

2.41e-041937043866667dd221612589ae50f5c52f73a183a49ce6
ToppCellcellseq-Epithelial-Epithelial_Alveolar-Secretory/RAS-RAS|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP2A6 CYP2A7 NEDD4L ATP1B1

2.41e-04193704525e0de0f25f3308daf49e7d4c8774562f1f40ad
ToppCellcellseq-Epithelial-Epithelial_Alveolar-Secretory/RAS|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP2A6 CYP2A7 NEDD4L ATP1B1

2.41e-041937042d18f39615043dfbff120a00f6540ffa93082c83
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP2A6 CYP2A7 NEDD4L ATP1B1

2.46e-041947045b29c843186c2394f5bec3b1d5ae284a0d931d85
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP2A6 CYP2A7 NEDD4L ATP1B1

2.46e-04194704ebcf6c6d0eb20a5d422becf5a730089230c8ba9a
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP2A6 CYP2A7 NEDD4L ATP1B1

2.46e-041947048c6e5ba27a988e0cd6b8c25cb9a30a0da2b1f7f9
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP2A6 CYP2A7 NEDD4L ATP1B1

2.46e-041947046e78e3046c5b172af92a84e25f982377a0aaac58
ToppCellnormal_Lung-Epithelial_cells-Club|normal_Lung / Location, Cell class and cell subclass

CYP2A6 CYP2A7 CYP2A13 NEDD4L

2.51e-04195704b46544ad5af04f4dbc2643637caa3d2d50d922ae
ToppCell15-Airway-Epithelial-Epithelial|Airway / Age, Tissue, Lineage and Cell class

SORBS2 AATK METRN MIA

2.51e-0419570456356a9aeb67b50a74425be2cd9c50d31416c1b3
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Club|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CYP2A6 CYP2A7 FOXQ1 NEDD4L

2.51e-04195704b9e8f405f6d837bb39b615836d3e2df349737c0e
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Club|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CYP2A6 CYP2A7 CYP2A13 NEDD4L

2.56e-041967044e4c632db73b1340d80bf40a7657cb4821084d3c
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Club|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

AATK FOXQ1 NEDD4L ATP1B1

2.56e-04196704d5f9168001e60bafec17fe6c702e68f5528edc20
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SORBS2 FOXQ1 TM4SF18 TDRD1

2.61e-0419770462c0a90869431e582bb7bb329e0b0cc59123d3d1
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CYP2A6 CYP2A7 NEDD4L MMP13

2.61e-04197704751f19b00f92e1334f653b870d3f7c0c149ff41a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SORBS2 FOXQ1 FIBCD1 TM4SF18

2.61e-04197704e567f91fa398fd306d025dcfe89bd50a60216537
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MMP11 MMP13 ENPEP MIA

2.61e-04197704c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Basal_1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CYP2A6 CYP2A7 NEDD4L MMP13

2.61e-041977042701864e49878c5f323f5133e2c4b0a5a7fff7f5
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SORBS2 FOXQ1 TM4SF18 TDRD1

2.61e-0419770416f0eb047df9d702518f82ee99c6e7dc1350b2fb
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Basal_1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CYP2A6 CYP2A7 NEDD4L MMP13

2.61e-0419770458d809ccb8cc4b1e76acf0b8f996cd0e2637290c
ToppCelldistal-Epithelial-Club-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CYP2A6 FOXQ1 NEDD4L ATP1B1

2.66e-04198704e56a5ffadfa4d1e34d34aec43eaf560cd80286e1
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Club|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CYP2A6 CYP2A13 FOXQ1 NEDD4L

2.66e-041987045d57acbe0d245f8bd217eeea07af060092898fbd
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP2A7 CYP2A13 SLC25A5 NDUFV1

2.66e-04198704e3d1c9428ee6f9bcf9cdaf2192d4ebea8cc2a47c
ToppCelldistal-2-Epithelial-Club|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CYP2A6 FOXQ1 NEDD4L ATP1B1

2.66e-041987043055c03896fbfac82a3072e51c0c54d68131cf1a
ToppCellBiopsy_Control_(H.)-Epithelial-SCGB3A2+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

CYP2A6 FOXQ1 NEDD4L ATP1B1

2.66e-041987041fe51f4beca0eef4ff117e6edaa646e35c0f9629
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CYP2A6 CYP2A7 FOXQ1 NEDD4L

2.71e-04199704a8bfc0b93ad9968cf52a25be86995ffe436bd636
ToppCelldistal-1-Epithelial-Club|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CYP2A6 CYP2A7 CYP2A13 NEDD4L

2.71e-041997048f0a72a95d0310ef2324c6975495c294b5a47cc8
ToppCellproximal-Epithelial-Club|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CYP2A6 FOXQ1 NEDD4L ATP1B1

2.71e-0419970499d23c0373f1ae5267bb3e51c5c88c8f52559ae4
Drug2'-methoxyacetophenone

CYP2A6 CYP2A7 CYP2A13

2.78e-083703CID000068481
Drugnicotine imine

CYP2A6 CYP2A13

9.32e-062702ctd:C034629
Drugpropargyl ether

CYP2A6 CYP2A13

9.32e-062702ctd:C531209
Drugalpha-nicotyrine

CYP2A6 CYP2A13

9.32e-062702ctd:C008615
DrugHempa

CYP2A6 CYP2A13

9.32e-062702ctd:D006492
DrugN-nitrosoguvacoline

CYP2A6 CYP2A13

9.32e-062702ctd:C036676
DrugN-nitrosomethylaniline

CYP2A6 CYP2A7 CYP2A13

9.89e-0614703CID000011957
Drugpenicillin

LYZL2 SLC22A11 SLC13A3 LYZL1

2.67e-0556704CID000002349
DrugNSC35549

CYP2A6 CYP2A7 CYP2A13

4.11e-0522703CID000411697
Drugclofibrate

CYP2A6 CYP2A7 CYP2A13 APOA5 ENPEP FGL2 GNPAT

4.76e-05311707CID000002796
Drugpiperonyl butoxide

CYP2A6 CYP2A7 CYP2A13 ENPEP

5.43e-0567704CID000005794
DrugNMPA

CYP2A6 CYP2A13

5.57e-054702CID000132101
DrugN'-nitrosoanatabine

CYP2A6 CYP2A13

5.57e-054702ctd:C032978
Drugsulfur

CYP2A6 CYP2A7 CYP2A13 B3GALT6 SQOR NDUFV1

5.80e-05219706CID000000402
Drug1h1q

CYP2A6 CYP2A7 CYP2A13 ENPEP

6.45e-0570704CID000001540
DrugC14845

CYP2A6 CYP2A7 CYP2A13

7.72e-0527703CID011954064
DrugBP-9,10-oxide

CYP2A6 CYP2A7 CYP2A13

7.72e-0527703CID000037456
DrugBrn 4136738

CYP2A6 CYP2A7 CYP2A13

7.72e-0527703CID000050331
Drug9-OH-BaP-4,5-oxide

CYP2A6 CYP2A7 CYP2A13

8.63e-0528703CID000115064
DrugN-methyl-N-2-(methylsulfinyl)ethylpropionic acid amide

CYP2A6 CYP2A13

9.26e-055702ctd:C062567
Drugbenzyl selenocyanate

CYP2A6 CYP2A13

9.26e-055702ctd:C054108
Drug1,6-anhydromuramic acid

LYZL2 LYZL1

9.26e-055702CID005492540
Drug11-H-14,15-EETA

CYP2A6 CYP2A7 CYP2A13

1.06e-0430703CID011954058
Drug19-hydroxytestosterone

CYP2A6 CYP2A7 CYP2A13

1.06e-0430703CID000150968
DrugBP-7,8-oxide

CYP2A6 CYP2A7 CYP2A13

1.29e-0432703CID000037455
DrugCoal Ash

AATK SLC25A5 PRKACG ATP1B1 MMP13

1.31e-04159705ctd:D060729
Drugmuramic lactam

LYZL2 LYZL1

1.39e-046702CID000161874
Drugacenaphthene-1-ol

CYP2A6 CYP2A13

1.39e-046702ctd:C023723
DrugC-MBT

LYZL2 LYZL1

1.39e-046702CID002723842
Drug5-mercaptouridine monophosphate

LYZL2 LYZL1

1.39e-046702CID003081517
DrugAC1L196J

CYP2A6 CYP2A13

1.39e-046702CID000000415
Drugmenthofuran

CYP2A6 CYP2A13

1.39e-046702ctd:C054487
DrugN'-nitrosoanabasine

CYP2A6 CYP2A13

1.39e-046702ctd:C010257
DrugAC1LCF1F

CYP2A6 SLC22A11 SLC13A3 ENPEP ABCB4

1.39e-04161705CID000627275
Drugperfluoro-n-heptanoic acid

APOA5 SLC22A11 ABCB4

1.42e-0433703ctd:C101815
Drug12(13)-EpOME

CYP2A6 CYP2A7 CYP2A13

1.56e-0434703CID000001416
DrugTCEO

CYP2A6 CYP2A7 CYP2A13

1.56e-0434703CID000028167
DrugAC1O5XSP

CYP2A6 CYP2A7 CYP2A13

1.56e-0434703CID006442739
DrugAC1L1CJI

CYP2A6 CYP2A7 CYP2A13

1.70e-0435703CID000001929
Drug15-H-11,12-EETA

CYP2A6 CYP2A7 CYP2A13

1.85e-0436703CID011954042
DrugAC1L3NGJ

CYP2A6 CYP2A7 CYP2A13

1.85e-0436703CID000092121
Drughexamethylphosphoramide

CYP2A6 CYP2A7 CYP2A13

1.85e-0436703CID000012679
Drugacenaphthene

CYP2A6 CYP2A13

1.94e-047702ctd:C042552
Drugtienilic acid

CYP2A6 CYP2A7 CYP2A13 SLC13A3

1.95e-0493704CID000038409
Druglansoprazole

CYP2A6 CYP2A7 CYP2A13 APBB3

1.95e-0493704CID000003883
DrugNicorette

CYP2A6 CYP2A7 CYP2A13 PRKACG MMP11 MMP13 DNMT1 FGL2

2.15e-04529708CID000000942
Drugcimetidine

CYP2A6 AOC1 SLC22A11 SLC13A3 ABCB4

2.27e-04179705CID000002756
Drugbromobenzene

CYP2A6 CYP2A7 CYP2A13 ENPEP

2.29e-0497704CID000007961
Drug11,14,15-THET

CYP2A6 CYP2A7 CYP2A13

2.35e-0439703CID006439531
Drugnicotine glucuronide

CYP2A6 ABCB4

2.58e-048702CID003035848
Drugpotassium selenate

LYZL2 LYZL1

2.58e-048702CID000062680
Diseaseserum metabolite measurement

SORBS2 NWD2 AOC1 APOA5 SLC22A11 SLC13A3 TM2D3 PKD1L2 ENPEP DNMT1 ABCB4

1.15e-059456911EFO_0005653
DiseaseLiddle syndrome (implicated_via_orthology)

NEDD4L NEDD4

3.22e-054692DOID:0050477 (implicated_via_orthology)
Diseaseabnormal vaginal discharge smell

SORBS2 MAP3K10

1.12e-047692EFO_0009408
Diseasemelanoma-derived growth regulatory protein measurement

CYP2A6 MIA

2.92e-0411692EFO_0008229
Diseasenicotine metabolite ratio

CYP2A6 CYP2A7

3.50e-0412692EFO_0007794
Diseasecaffeine metabolite measurement

CYP2A6 CYP2A7

8.98e-0419692EFO_0007872
Diseaseintestinal permeability measurement

AATK LYZL1

1.69e-0326692EFO_0011031

Protein segments in the cluster

PeptideGeneStartEntry
AFFAGDGSWYRALVK

TDRD1

771

Q9BXT4
LYWGFFSGRGRVKPG

B3GALT6

181

Q96L58
GRTGGSWFKILLFYV

ATP1B1

26

P05026
RGEQATFDWVFKGYG

CYP2A6

101

P11509
AGLYGRLEWDGFFST

DNMT1

1511

P26358
GLSSRLQKWFYERFG

GRAMD4

161

Q6IC98
GGVDKRTQFWLYFAG

SLC25A5

101

P05141
GFWDYFSQTSGDKGR

APOA5

26

Q6Q788
RGVMDSDGYFWFVGR

ACSM4

456

P0C7M7
AVLYGGWSFAFRLRS

AOC1

316

P19801
DYFLGVWSGGRRKAF

NWD2

761

Q9ULI1
YKQGFGSIRGDFWLG

ANGPTL7

191

O43827
GSVLFILWKTYFGRG

ARL10

21

Q8N8L6
KKWRRFGASLYGGSD

DOK2

21

O60496
VGGFGKVYRALWRGE

MAP3K10

106

Q02779
FSRAGLDNYWGFSLG

LYZL1

31

Q6UWQ5
FSRAGLDNYWGFSLG

LYZL2

31

Q7Z4W2
GLDYGGVAREWFFLI

NEDD4

1001

P46934
FLFMGWSRFGEARLG

METRN

251

Q9UJH8
IFIFRGRKFWALNGY

MMP13

346

P45452
SLEGSGRQGYFRWKE

KAT14

136

Q9H8E8
YSELVGFWSVEFGGR

NIPSNAP3B

66

Q9BS92
EFAGWLNGSLVGFYR

ENPEP

191

Q07075
GGWLAAFWKDFRRRF

NAT10

761

Q9H0A0
SAWATRAFFRYGGEA

NUP155

566

O75694
RGFSGVLGFREFFKW

PKD1L2

1986

Q7Z442
TFFAGFIVGFIRGWK

ABCB4

201

P21439
GFASVGYVRGWLFVL

OR6N2

16

Q8NGY6
WGVGSSKGRDRDFAF

APBB3

201

O95704
AKARGDFLYRWGNPA

PRKACG

21

P22612
RGEQATFDWLFKGYG

CYP2A13

101

Q16696
RTFGGNKLYWAVFSE

GNPAT

211

O15228
TYKQGFGSRLGEFWL

FCN2

161

Q15485
RGEQATFDWVFKGYG

CYP2A7

101

P20853
YKAGFGNLRREFWLG

FGL2

271

Q14314
GSVNFFRGWDAYRDG

FIBCD1

291

Q8N539
FRGWDAYRDGFGRLT

FIBCD1

296

Q8N539
GSFIWGLLSYRFGRK

SLC22A11

156

Q9NSA0
YGGLSFRGWRKNKSE

SLC13A3

301

Q8WWT9
DGIKGGIRRWNYFFP

PRIMPOL

391

Q96LW4
GKFPFFRGSYTGWRN

FOXQ1

151

Q9C009
YVFSKLKGRGRLFWG

MIA

71

Q16674
GELFFFKAGFVWRLR

MMP11

306

P24347
LRGYWGGPAFLRKLF

SQOR

431

Q9Y6N5
RGYQAAGAELWRKFA

TMC3

96

Q7Z5M5
AWRAGFIIYTAALGF

SSTR3

201

P32745
WAGSVGRTFGYFPKD

MIA3

86

Q5JRA6
TSRGLNFEYKWEAGR

AATK

471

Q6ZMQ8
WFAGFGRERNSGTKL

NDUFV1

261

P49821
SFFRGWNDYKLGFGR

MFAP4

91

P55083
AYGASFLSFLGGIRW

TMEM69

131

Q5SWH9
DGWFVGTSRRTKFFG

SORBS2

1076

O94875
GLLAGLAYAAGAFRW

RHBDD3

171

Q9Y3P4
IRGSWQFSFDGRKFL

ULBP3

136

Q9BZM4
FLYLGSGGWRFIRVF

SLC27A4

31

Q6P1M0
GWEYAFEGTAGRFLT

TM4SF18

126

Q96CE8
ERKYLQGFVAFGWGS

SCTR

251

P47872
LNAWRYVGAVGGFLF

SERINC5

151

Q86VE9
IYWLTFAVGRSFRGF

TMEM79

326

Q9BSE2
FVGDYTLSFWRNGKV

PLCG1

591

P19174
SVWVGGRGKVYLFDF

SEMA7A

86

O75326
FSFVTNKYPRGVGWR

TMEM117

51

Q9H0C3
RYGSRKFASFLLGSW

UBAC2

86

Q8NBM4
WTYGITRGGRVFFIN

PLEKHA5

16

Q9HAU0
GQYFTLWDRIGGSFK

SC5D

241

O75845
ALLFGWFRKFVAERG

ZMYND15

16

Q9H091
ADRFYLGQWREGLGK

TM2D3

201

Q9BRN9
FIGFGLRFGAKWNFA

TRPM7

936

Q96QT4
GGVFTRYWFALKRGY

XKR9

86

Q5GH70
RYRGATGGDLFWAPF

ZBTB3

31

Q9H5J0
KGLDYGGVAREWFFL

NEDD4L

656

Q96PU5