Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	pre-mRNA binding	ZRSR2P1 ZRSR2 PRPF8 EP300	1.15e-04	64	78	4	GO:0036002
GeneOntologyMolecularFunction	calcium, potassium:sodium antiporter activity	SLC24A5 SLC24A1	1.49e-04	5	78	2	GO:0008273
GeneOntologyMolecularFunction	acetylation-dependent protein binding	BRD3 PHIP EP300	2.38e-04	31	78	3	GO:0140033
GeneOntologyMolecularFunction	pre-mRNA 3'-splice site binding	ZRSR2P1 ZRSR2	3.12e-04	7	78	2	GO:0030628
GeneOntologyMolecularFunction	calcium:sodium antiporter activity	SLC24A5 SLC24A1	6.64e-04	10	78	2	GO:0005432
GeneOntologyCellularComponent	CORVET complex	VPS33B VPS8	2.93e-04	7	79	2	GO:0033263
GeneOntologyCellularComponent	U2AF complex	ZRSR2P1 ZRSR2	2.93e-04	7	79	2	GO:0089701
Domain	PLC-beta_CS	PLCB3 PLCB4	5.15e-05	3	78	2	IPR009535
Domain	DUF1154	PLCB3 PLCB4	5.15e-05	3	78	2	PF06631
Domain	PLC-beta	PLCB3 PLCB4	1.03e-04	4	78	2	IPR016280
Domain	Bromodomain_CS	BRD3 PHIP EP300	1.70e-04	26	78	3	IPR018359
Domain	U2AF_small	ZRSR2P1 ZRSR2	1.71e-04	5	78	2	IPR009145
Domain	K/Na/Ca-exchanger	SLC24A5 SLC24A1	1.71e-04	5	78	2	IPR004481
Domain	BROMODOMAIN_1	BRD3 PHIP EP300	4.92e-04	37	78	3	PS00633
Domain	Bromodomain	BRD3 PHIP EP300	5.32e-04	38	78	3	PF00439
Domain	NaCa_Exmemb	SLC24A5 SLC24A1	6.08e-04	9	78	2	IPR004837
Domain	Na_Ca_ex	SLC24A5 SLC24A1	6.08e-04	9	78	2	PF01699
Domain	BROMODOMAIN_2	BRD3 PHIP EP300	6.66e-04	41	78	3	PS50014
Domain	BROMO	BRD3 PHIP EP300	7.15e-04	42	78	3	SM00297
Domain	Bromodomain	BRD3 PHIP EP300	7.15e-04	42	78	3	IPR001487
Domain	-	BRD3 PHIP EP300	7.15e-04	42	78	3	1.20.920.10
Domain	PLipase_C_Pinositol-sp_Y	PLCB3 PLCB4	1.75e-03	15	78	2	IPR001711
Domain	EF-hand_like	PLCB3 PLCB4	1.75e-03	15	78	2	PF09279
Domain	PIPLC_Y_DOMAIN	PLCB3 PLCB4	1.75e-03	15	78	2	PS50008
Domain	PI-PLC_fam	PLCB3 PLCB4	1.75e-03	15	78	2	IPR001192
Domain	PLC_EF-hand-like	PLCB3 PLCB4	1.75e-03	15	78	2	IPR015359
Domain	PI-PLC-Y	PLCB3 PLCB4	1.75e-03	15	78	2	PF00387
Domain	PLCYc	PLCB3 PLCB4	1.75e-03	15	78	2	SM00149
Domain	P4Hc	OGFOD2 PLOD1	1.99e-03	16	78	2	SM00702
Domain	Pro_4_hyd_alph	OGFOD2 PLOD1	1.99e-03	16	78	2	IPR006620
Domain	DUF1605	DHX37 DHX30	2.25e-03	17	78	2	IPR011709
Domain	OB_NTP_bind	DHX37 DHX30	2.25e-03	17	78	2	PF07717
Domain	HA2	DHX37 DHX30	2.52e-03	18	78	2	SM00847
Domain	HA2	DHX37 DHX30	2.52e-03	18	78	2	PF04408
Domain	Helicase-assoc_dom	DHX37 DHX30	2.52e-03	18	78	2	IPR007502
Domain	PI-PLC-X	PLCB3 PLCB4	2.52e-03	18	78	2	PF00388
Domain	PLCXc	PLCB3 PLCB4	2.52e-03	18	78	2	SM00148
Domain	PIPLC_X_DOMAIN	PLCB3 PLCB4	2.81e-03	19	78	2	PS50007
Domain	PLipase_C_PInositol-sp_X_dom	PLCB3 PLCB4	2.81e-03	19	78	2	IPR000909
Domain	FE2OG_OXY	OGFOD2 PLOD1	3.43e-03	21	78	2	PS51471
Domain	Oxoglu/Fe-dep_dioxygenase	OGFOD2 PLOD1	4.12e-03	23	78	2	IPR005123
Domain	-	PLCB3 PLCB4	4.85e-03	25	78	2	3.20.20.190
Domain	PLC-like_Pdiesterase_TIM-brl	PLCB3 PLCB4	4.85e-03	25	78	2	IPR017946
Pathway	REACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA	TUT4 YAP1 EP300	4.31e-05	17	58	3	M48025
Pubmed	Mouse U2af1-rs1 is a neomorphic imprinted gene.	ZRSR2P1 COMMD1 ZRSR2	4.50e-08	4	79	3	9001233
Pubmed	Allelic variants between mouse substrains BALB/cJ and BALB/cByJ influence mononuclear cardiomyocyte composition and cardiomyocyte nuclear ploidy.	ZRSR2P1 ZRSR2 CA5B	6.27e-07	8	79	3	32371981
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA4F B4GALNT4 POMGNT2 TULP4 OBSCN NPRL3 DYRK1A POFUT1 MED13L DYSF EP300 DHX30 GGT7	1.19e-06	1105	79	13	35748872
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	COL4A3 GAPVD1 DHX37 OBSCN BRD3 PLCB4 PRPF8 DYSF PLOD1	1.96e-06	497	79	9	36774506
Pubmed	ZRSR1 co-operates with ZRSR2 in regulating splicing of U12-type introns in murine hematopoietic cells.	ZRSR2P1 ZRSR2	5.09e-06	2	79	2	33691379
Pubmed	Comparative analyses of genomic imprinting and CpG island-methylation in mouse Murr1 and human MURR1 loci revealed a putative imprinting control region in mice.	ZRSR2P1 COMMD1	5.09e-06	2	79	2	16305817
Pubmed	Phospholipase Cbeta 3 mediates the scratching response activated by the histamine H1 receptor on C-fiber nociceptive neurons.	PLCB3 PLCB4	5.09e-06	2	79	2	17114052
Pubmed	Zrsr2 and functional U12-dependent spliceosome are necessary for follicular development.	ZRSR2P1 ZRSR2	5.09e-06	2	79	2	35198906
Pubmed	The mouse Murr1 gene is imprinted in the adult brain, presumably due to transcriptional interference by the antisense-oriented U2af1-rs1 gene.	COMMD1 ZRSR2	5.09e-06	2	79	2	14673161
Pubmed	Growing oocyte-specific transcription-dependent de novo DNA methylation at the imprinted Zrsr1-DMR.	COMMD1 ZRSR2	5.09e-06	2	79	2	29875017
Pubmed	Complementary stripes of phospholipase Cbeta3 and Cbeta4 expression by Purkinje cell subsets in the mouse cerebellum.	PLCB3 PLCB4	5.09e-06	2	79	2	16566000
Pubmed	BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy.	BCL6 EP300	5.09e-06	2	79	2	21041953
Pubmed	NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.	DOCK8 DHX37 OBSCN MRPS9 PRPF8 AK7 DHX30	1.11e-05	333	79	7	32665550
Pubmed	Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1.	ZRSR2P1 ZRSR2	1.53e-05	3	79	2	8586425
Pubmed	Concurrent Zrsr2 mutation and Tet2 loss promote myelodysplastic neoplasm in mice.	ZRSR2P1 ZRSR2	1.53e-05	3	79	2	36030305
Pubmed	Plasmid-Mediated Gene Therapy in Mouse Models of Limb Girdle Muscular Dystrophy.	SGCA DYSF	1.53e-05	3	79	2	31890729
Pubmed	BCL6 confers KRAS-mutant non-small-cell lung cancer resistance to BET inhibitors.	BRD3 BCL6	1.53e-05	3	79	2	33393503
Pubmed	Reciprocal occupancy of BCL6 and STAT5 on Growth Hormone target genes: contrasting transcriptional outcomes and promoter-specific roles of p300 and HDAC3.	BCL6 EP300	1.53e-05	3	79	2	25088465
Pubmed	Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking.	TMEM131 TRAPPC8	1.53e-05	3	79	2	32095531
Pubmed	Acetylation inactivates the transcriptional repressor BCL6.	BCL6 EP300	1.53e-05	3	79	2	12402037
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	IGBP1 DYRK1A BRD3 MED13L MAP7 LIN9 PHIP EP300 PLIN3	1.59e-05	645	79	9	25281560
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	GAPVD1 USP11 DHX37 NUP210 PRPF8 PLOD1 PHIP EPB41L2 DHX30	1.75e-05	653	79	9	22586326
Pubmed	Patterns of expression for the mRNA corresponding to the four isoforms of phospholipase Cbeta in mouse brain.	PLCB3 PLCB4	3.05e-05	4	79	2	9753089
Pubmed	Phospholipase C-β1 potentiates glucose-stimulated insulin secretion.	PLCB3 PLCB4	3.05e-05	4	79	2	31268747
Pubmed	p300-mediated acetylation of COMMD1 regulates its stability, and the ubiquitylation and nucleolar translocation of the RelA NF-κB subunit.	COMMD1 EP300	3.05e-05	4	79	2	25074812
Pubmed	Inactivating mutations of acetyltransferase genes in B-cell lymphoma.	BCL6 EP300	3.05e-05	4	79	2	21390126
Pubmed	PLCβ isoforms differ in their subcellular location and their CT-domain dependent interaction with Gαq.	PLCB3 PLCB4	3.05e-05	4	79	2	23006664
Pubmed	Cloning and mapping of the U2af1-rs2 gene with a high transmission distortion in interspecific backcross progeny.	ZRSR2P1 ZRSR2	3.05e-05	4	79	2	7558001
Pubmed	Phospholipase C isozymes selectively couple to specific neurotransmitter receptors.	PLCB3 PLCB4	3.05e-05	4	79	2	9305844
Pubmed	Expression of phospholipase C beta family isoenzymes in C2C12 myoblasts during terminal differentiation.	PLCB3 PLCB4	3.05e-05	4	79	2	15174099
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	POMGNT2 NUP210 TMEM131 POFUT1 PLOD1	3.73e-05	164	79	5	32409323
Pubmed	Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DENND6A DOCK8 DYSF GGT7	4.34e-05	85	79	4	15449545
Pubmed	NHERF2/SIP-1 interacts with mouse SRY via a different mechanism than human SRY.	YAP1 EP300	5.07e-05	5	79	2	16166090
Pubmed	Expression of potassium-dependent sodium-calcium exchanger in the murine lens.	SLC24A5 SLC24A1	5.07e-05	5	79	2	29128492
Pubmed	Cardiac ankyrin repeat protein is a marker of skeletal muscle pathological remodelling.	SGCA DYSF	5.07e-05	5	79	2	19143834
Pubmed	Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth.	YAP1 EP300	5.07e-05	5	79	2	27720608
Pubmed	DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly.	DYRK1A LIN9	5.07e-05	5	79	2	21498570
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	SEMA4F COMMD1 MRPL15 DHX37 NUP210 MRPS9 POFUT1 MAP7 PLOD1	5.36e-05	754	79	9	33060197
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	GAPVD1 IGBP1 VPS33B DOCK8 YAP1 TBC1D5 PLOD1	7.12e-05	446	79	7	24255178
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	IGBP1 SMG7 USP11 NUP210 DYRK1A CDK5RAP1 TMEM131 PLOD1	7.14e-05	606	79	8	36538041
Pubmed	Fukutin-related protein associates with the sarcolemmal dystrophin-glycoprotein complex.	SGCA DYSF	7.60e-05	6	79	2	17452335
Pubmed	Expression and immunohistochemical localization of eight phospholipase C isoforms in adult male mouse cerebellar cortex.	PLCB3 PLCB4	7.60e-05	6	79	2	8739298
Pubmed	p300-mediated acetylation stabilizes the Th-inducing POK factor.	PRPF8 EP300	7.60e-05	6	79	2	20810990
Pubmed	Cloning and tissue expression of cDNAs from chromosome 5q21-22 which is frequently deleted in advanced lung cancer.	ZRSR2P1 DCP2	7.60e-05	6	79	2	9490301
Pubmed	The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb.	DYRK1A LIN9	7.60e-05	6	79	2	30206359
Pubmed	Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies.	SGCA DYSF	7.60e-05	6	79	2	26060189
Pubmed	Identification of a T follicular helper cell subset that drives anaphylactic IgE.	DOCK8 BCL6	7.60e-05	6	79	2	31371561
Pubmed	Increased activity of hypoxia-inducible factor 1 is associated with early embryonic lethality in Commd1 null mice.	COMMD1 ZRSR2	7.60e-05	6	79	2	17371845
Pubmed	Purification and characterization of membrane-bound phospholipase C specific for phosphoinositides from human platelets.	PLCB3 PLCB4	7.60e-05	6	79	2	2841328
Pubmed	DYRK1A interacts with histone acetyl transferase p300 and CBP and localizes to enhancers.	DYRK1A EP300	7.60e-05	6	79	2	30137413
Pubmed	The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage.	YAP1 EP300	7.60e-05	6	79	2	15893728
Pubmed	Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition.	ZRSR2P1 ZRSR2	7.60e-05	6	79	2	33846634
Pubmed	Human transcription factor protein interaction networks.	SMG7 MRPL15 YAP1 USP11 DHX37 MRPS9 ETV6 MAP7 LIN9 EP300 DHX30 SENP5	8.86e-05	1429	79	12	35140242
Pubmed	The CRL4DCAF6 E3 ligase ubiquitinates CtBP1/2 to induce apoptotic signalling and promote intervertebral disc degeneration.	COMMD1 DOCK8 PLCB3 PHIP EP300	9.32e-05	199	79	5	36688959
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	IGBP1 VPS33B YAP1 TBC1D5 NUP210 TMEM131 POFUT1 TRAPPC8 PLOD1 EPB41L2	9.36e-05	1007	79	10	34597346
Pubmed	Aldo-keto reductase 1b7, a novel marker for renin cells, is regulated by cyclic AMP signaling.	CYP11B2 EP300	1.06e-04	7	79	2	26180185
Pubmed	A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome.	YAP1 EP300	1.06e-04	7	79	2	16332960
Pubmed	Histone recognition and large-scale structural analysis of the human bromodomain family.	BRD3 PHIP	1.06e-04	7	79	2	22464331
Pubmed	LPCAT3 Is Transcriptionally Regulated by YAP/ZEB/EP300 and Collaborates with ACSL4 and YAP to Determine Ferroptosis Sensitivity.	YAP1 EP300	1.06e-04	7	79	2	37166352
Pubmed	Common pathological mechanisms in mouse models for muscular dystrophies.	SGCA DYSF	1.06e-04	7	79	2	16306063
Pubmed	Genetic dissection of gustatory sensitivity to bitterness (sucrose octaacetate) in mice.	PLCB3 PLCB4	1.06e-04	7	79	2	10609087
Pubmed	A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA.	ZRSR2P1 ZRSR2	1.06e-04	7	79	2	9237760
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MRPL15 USP11 NUP210 MRPS9 CDK5RAP1 TMEM131 MAP7 TRAPPC8 PRPF8 PLOD1 EPB41L2 DHX30	1.29e-04	1487	79	12	33957083
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	PPIG GAPVD1 SMG7 VPS33B DHX37 TBC1D5 DYRK1A TMEM131 PLOD1	1.37e-04	853	79	9	28718761
Pubmed	Mice develop normally without tenascin.	COL4A3 TNXB	1.41e-04	8	79	2	1383086
Pubmed	Molecular genetics of the human MHC complement gene cluster.	C2 TNXB	1.41e-04	8	79	2	10072631
Pubmed	Quantitative Mass Spectrometry Identifies Novel Host Binding Partners for Pathogenic Escherichia coli Type III Secretion System Effectors.	MAP7 EP300	1.41e-04	8	79	2	27018634
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	COMMD1 FEZF2 ZRSR2 USP11 DYRK1A MRPS9 TMEM131 MED13L PRPF8 EP300 DHX30	1.52e-04	1285	79	11	35914814
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	SEMA4F PPIG PRPF8 PHIP EP300 DHX30	1.69e-04	358	79	6	32460013
Pubmed	Exogenous human immunodeficiency virus type-1 Tat protein selectively stimulates a phosphatidylinositol-specific phospholipase C nuclear pathway in the Jurkat T cell line.	PLCB3 PLCB4	1.82e-04	9	79	2	7589147
Pubmed	Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat.	PLCB3 PLCB4	1.82e-04	9	79	2	10501179
Pubmed	The protein interaction landscape of the human CMGC kinase group.	PPIG ZRSR2 USP11 DYRK1A BRD3 MED13L PRPF8 EP300	1.83e-04	695	79	8	23602568
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	TUT4 USP11 MRPS9 PRPF8 EPB41L2	2.03e-04	235	79	5	30258100
Pubmed	Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity.	VPS33B VPS8	2.27e-04	10	79	2	26463206
Pubmed	Expression of phospholipase C isozymes by murine B lymphocytes.	PLCB3 PLCB4	2.27e-04	10	79	2	2033248
Pubmed	HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia.	MED13L EP300	2.27e-04	10	79	2	23746844
Pubmed	Implantation failure in mice with a disruption in Phospholipase C beta 1 gene: lack of embryonic attachment, aberrant steroid hormone signalling and defective endocannabinoid metabolism.	PLCB3 PLCB4	2.27e-04	10	79	2	23295235
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	TUT4 SMG7 DHX37 TMEM131 PRPF8 DYSF PLOD1 PLIN3	2.41e-04	724	79	8	36232890
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	SEMA4F GAPVD1 DENND6A OBSCN BRD3 PLCB3 PRPF8 EPB41L2	2.69e-04	736	79	8	29676528
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	ZRSR2P1 PPIG MRPS9 BRD3 DHX30	2.74e-04	251	79	5	31076518
Pubmed	Organizations and gene duplications of the human and mouse MHC complement gene clusters.	C2 TNXB	2.76e-04	11	79	2	10686478
Pubmed	Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.	SEMA4F VPS33B DOCK8 SGCA CDK5RAP1 ETV6 AKAP10 AMMECR1	2.84e-04	742	79	8	26871637
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	PPIG USP11 MRPS9 PHIP DHX30	2.85e-04	253	79	5	29911972
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	GAPVD1 IGBP1 VPS33B TBC1D5 TMEM131 TRAPPC8 PLIN3	3.14e-04	568	79	7	37774976
Pubmed	Trisomy 21 Alters DNA Methylation in Parent-of-Origin-Dependent and -Independent Manners.	DYRK1A TMEM131	3.31e-04	12	79	2	27100087
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	YAP1 MRPS9 BCL6 MED13L LIN9	3.71e-04	268	79	5	33640491
Pubmed	A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.	YAP1 POFUT1	3.91e-04	13	79	2	32929274
Pubmed	Characterization of zygotic genome activation-dependent maternal mRNA clearance in mouse.	TUT4 YAP1	3.91e-04	13	79	2	31777931
Pubmed	Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.	TUT4 DCP2	3.91e-04	13	79	2	18172165
Pubmed	The histone deacetylase 9 gene encodes multiple protein isoforms.	ETV6 BCL6	4.55e-04	14	79	2	12590135
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	DENND6A VPS33B DHX37 TBC1D5 VPS8	4.90e-04	285	79	5	34369648
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	GAPVD1 USP11 NUP210 DYRK1A PLOD1 DHX30	5.06e-04	440	79	6	34244565
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	PPIG GAPVD1 IGBP1 TULP4 YAP1 NPRL3 MED13L PRPF8 PLIN3 DHX30	5.17e-04	1247	79	10	27684187
Pubmed	Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle.	PLCB3 PLCB4	5.25e-04	15	79	2	28578927
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	NGRN TUT4 MRPL15 VPS33B USP11 MRPS9 CDK5RAP1 TMEM131 PLOD1 PHIP DHX30	5.53e-04	1496	79	11	32877691
Pubmed	Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes.	YAP1 LIN9	5.99e-04	16	79	2	32469866
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	USP11 DYRK1A BRD3 PRPF8 DHX30	6.18e-04	300	79	5	28561026
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	BRD3 PHIP EP300	6.77e-04	75	79	3	25593309
Pubmed	Comparative mapping of the imprinted U2afbpL gene on mouse chromosome 11 and human chromosome 5.	ZRSR2P1 ZRSR2	6.78e-04	17	79	2	7956352
Pubmed	Targeted Disruption of Lats1 and Lats2 in Mice Impairs Adrenal Cortex Development and Alters Adrenocortical Cell Fate.	YAP1 CYP11B2	6.78e-04	17	79	2	32243503
Interaction	MED23 interactions	MRPL15 SGCA YAP1 DYRK1A BRD3 BCL6 MED13L MAP7 EP300	9.76e-07	266	79	9	int:MED23
Interaction	FAM120A interactions	NGRN TUT4 SMG7 MRPL15 YAP1 MRPS9 MAP7 DYSF PHIP DHX30	1.06e-06	349	79	10	int:FAM120A
Interaction	SRSF5 interactions	PPIG MRPL15 ZRSR2 DOCK8 USP11 DHX37 DYRK1A MRPS9 PRPF8 EP300 DHX30	2.32e-06	474	79	11	int:SRSF5
Interaction	SRSF1 interactions	PPIG IGBP1 ZRSR2 USP11 DYRK1A MRPS9 BRD3 MAP7 PRPF8 EP300 DHX30	1.33e-05	570	79	11	int:SRSF1
Interaction	MOV10 interactions	COL4A3 TUT4 SMG7 MRPL15 YAP1 USP11 OGFOD2 OBSCN DYRK1A PLCB3 POFUT1 MAP7 LIN9 EP300 EPB41L2 DHX30	3.59e-05	1297	79	16	int:MOV10
Interaction	NUDCD2 interactions	IGBP1 DOCK8 DHX37 NUP210 OBSCN MRPS9 PRPF8 AK7 DHX30	4.15e-05	424	79	9	int:NUDCD2
Cytoband	5q22.2	ZRSR2P1 DCP2	1.04e-04	9	79	2	5q22.2
GeneFamily	DEAH-box helicases	DHX37 DHX30	1.02e-03	16	54	2	500
GeneFamily	Phospholipases\|C2 domain containing phospholipases	PLCB3 PLCB4	1.45e-03	19	54	2	832
Coexpression	PUJANA_ATM_PCC_NETWORK	SEMA4F PPIG IGBP1 SMG7 TBC1D5 DCP2 NUP210 OBSCN ETV6 PLCB4 BCL6 AMMECR1 SLC24A1 PHIP EP300 PLIN3 SENP5	6.85e-07	1394	79	17	M9585
Coexpression	GSE15330_WT_VS_IKAROS_KO_HSC_UP	SEMA4F DENND6A ZRSR2 NUP210 PHIP PRX SLC23A3	2.47e-06	200	79	7	M7040
Computational	Neighborhood of SMO	SEMA4F POMGNT2 DHX37 SNX33 GGT7	7.99e-06	60	50	5	GCM_SMO
Disease	sexual dimorphism measurement	GAPVD1 SPAG4 NPRL3 CDK5RAP1 ETV6 PXYLP1 PLCB3 BCL6 DYSF PHIP EPB41L2 GGT7	2.81e-05	1106	77	12	EFO_0021796
Disease	Muscular Dystrophies, Limb-Girdle	POMGNT2 SGCA DYSF	8.02e-05	32	77	3	C0686353
Disease	Neurodevelopmental Disorders	DOCK8 DYRK1A MED13L DHX30	1.05e-04	93	77	4	C1535926
Disease	aminoadipic acid measurement	COL4A3 KBTBD8 EPB41L2	3.07e-04	50	77	3	EFO_0010459
Disease	Autosomal recessive limb-girdle muscular dystrophy	SGCA DYSF	5.99e-04	14	77	2	cv:C2931907
Disease	susceptibility to cold sores measurement	TBC1D5 DYSF TNXB	6.64e-04	65	77	3	EFO_0008402
Disease	T-Cell Lymphoma	BCL6 EP300	7.88e-04	16	77	2	C0079772
Disease	muscular dystrophy (is_implicated_in)	SGCA DYSF	8.91e-04	17	77	2	DOID:9884 (is_implicated_in)
Disease	X-11470 measurement	C2 TNXB	1.12e-03	19	77	2	EFO_0021241
Disease	hypertension	VPS33B CYP11B2 NPRL3 PLCB3 TNXB	1.26e-03	307	77	5	EFO_0000537
Disease	mean platelet volume	SEMA4F EFHC1 DOCK8 TBC1D5 DYRK1A AKAP10 BRD3 LIN9 PHIP	1.34e-03	1020	77	9	EFO_0004584
Disease	Arthrogryposis	VPS33B VPS8	1.37e-03	21	77	2	C0003886
Disease	ubiquitin carboxyl-terminal hydrolase 25 measurement	C2 TNXB	1.50e-03	22	77	2	EFO_0021881
Disease	eosinophil count	EFHC1 TBC1D5 DYRK1A TMEM131 BRD3 PLCB3 BCL6 DYSF PLOD1 TNXB TEX28	1.62e-03	1488	77	11	EFO_0004842
Disease	eye color	SLC24A5 TULP4 ETV6	1.71e-03	90	77	3	EFO_0003949
Disease	complement C4b measurement	C2 TNXB	1.94e-03	25	77	2	EFO_0008092
Disease	Squamous cell carcinoma of esophagus	FAT2 TNXB EP300	1.99e-03	95	77	3	C0279626
Disease	Limb-girdle muscular dystrophy	SGCA DYSF	2.10e-03	26	77	2	cv:C0686353
Disease	obesity (implicated_via_orthology)	TBC1D5 PLCB3 MED13L PLIN3	2.45e-03	215	77	4	DOID:9970 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
IFPTPDPAALKDRRM	EP300	591	Q09472
RFAKMPDEPVEAPAL	BRD3	411	Q15059
RKFQIPRFMPARPCS	CA5B	21	Q9Y2D0
LNPERMFRKPIPSTV	COL4A3	1636	Q01955
RPDPGPAMSFFRRKV	AKAP10	16	O43572
RDPQRSNKPGELPMF	BTBD11	391	A6QL63
APNKFFMAIPFIRPL	DCP2	221	Q8IU60
MPQTFRDPATAPLRK	DYRK1A	81	Q13627
PRSRLEKMVPFQVPE	DHX30	796	Q7L2E3
ENRPQMLETKVFPRP	C16orf46	361	Q6P387
EVFPPFRLMPRKVTL	NUP210	1076	Q8TEM1
PGQRLLFRFMKTPDE	ETV6	411	P41212
DEPLMTPLRERFLQP	OGFOD2	186	Q6N063
GQKQRPSRFFMTPPR	LIN9	286	Q5TKA1
KIEQLPMPPAATFIR	MED13L	981	Q71F56
RNSMDRPKLFVTPPE	MAP7	266	Q14244
FQKIRRQMEAPGAPP	NGRN	66	Q9NPE2
KPEEKRFLLEEPMPF	LY6K	96	Q17RY6
SPRSVMEKNNLFPPR	SLC24A1	271	O60721
KVPPPRDFHINLFRM	C2	721	P06681
RFVSAMPKAPIPFRK	GAPVD1	981	Q14C86
LKRNFMESTPEPRPN	EPB41L2	651	O43491
FPFPLEMENKRAPLP	FAT2	4226	Q9NYQ8
PPNMSERFRETFLPS	GGT7	281	Q9UJ14
ERPPVKPFILTRNMA	IGBP1	236	P78318
DPSPKREAPTMILFN	NPRL3	111	Q12980
AALRTMIPFRPKPRF	ABCC11	66	Q96J66
RFMPKPVFVPDVALI	POMGNT2	141	Q8NAT1
LEFPFPKPDMITRLE	POGK	86	Q9P215
FVVRYKPDEQPSLMP	PLOD1	641	Q02809
RFPLMEDTFIEKIPP	KBTBD8	241	Q8NFY9
EIPPIPENRFLMRKS	PPIG	276	Q13427
EQLVPPRMLERFTPK	OBSCN	5366	Q5VST9
KPEFMRRPDKSFDPF	PLCB3	701	Q01970
EMLPVKPFPENRTRP	DOCK8	526	Q8NF50
PPQLRQFLPEEFMKT	DENND6A	471	Q8IWF6
EEFRDVRMPVANPFP	BCL6	211	P41182
VRMPVANPFPKERAL	BCL6	216	P41182
PEVPPEEFRPFLAKM	COMMD1	41	Q8N668
DPFPLLMNRQRVPKV	EFHC1	286	Q5JVL4
PDVLSPKAVQRFLPM	CYP11B2	146	P19099
PEKVPLPAQRQMSRF	GPRIN3	281	Q6ZVF9
AKPAVFIPVNRSPEM	DHX37	231	Q8IY37
MNPKLEDPRRPDTSF	DYSF	2011	O75923
MAKTSEPRAPFEPRP	FEZF2	36	Q8TBJ5
RPSSFFGMDRPPKLR	POFUT1	371	Q9H488
VPFFLRGQPIPKRML	MRPL15	191	Q9P015
KPDFMRRPDRTFDPF	PLCB4	676	Q15147
TFIRDHPLMDRPVFP	SEMA4F	406	O95754
PPKPEQVESRALTMF	PLIN3	316	O60664
FRPEQDPVPRMPFEK	SMG7	901	Q92540
MAFRPKPPLERQDSL	SNX33	156	Q8WV41
RSPKPMCPLENLVRF	PXYLP1	441	Q8TE99
PMEKLFRVIAPPLNA	VPS8	696	Q8N3P4
FRESLMVFADPRSPP	TMEM151A	266	Q8N4L1
DLRQEMPPPRVFKSF	SPAG4	121	Q9NPE6
REVPRPLSTLPMFNV	SGCA	351	Q16586
SPFTAQEARMPQKPR	SLC23A3	526	Q6PIS1
DMLRPDPRDTFFLTP	B4GALNT4	316	Q76KP1
RFPPMTRDELPRLFC	AMMECR1	201	Q9Y4X0
PEMRIRFTSPHPKDF	CDK5RAP1	366	Q96SZ6
FKRMRFPPFDDEEPP	PRPF8	161	Q6P2Q9
RPEFVIMDPRTDSKP	TULP4	481	Q9NRJ4
RPRTDPQPSDFPMKF	SENP5	156	Q96HI0
PAKFTERPRPGVQMI	PHIP	311	Q8WWQ0
LFPSGLFEKRARPVM	MRPS9	111	P82933
PEVALKMPRLSFPRF	PRX	351	Q9BXM0
RPIRFEPPMLDFHEQ	TMEM131	106	Q92545
PFTEMKLRPRNFRSP	TNXB	4226	P22105
PQTVPMRLRKLPDSF	YAP1	81	P46937
MRLRKLPDSFFKPPE	YAP1	86	P46937
DPPSVFNMPEADLKR	SLC24A5	291	Q71RS6
PPEMELLKFFRPENI	TRAPPC8	1281	Q9Y2L5
PEPPVDFRVMEKDRA	ZRSR2P1	161	Q15695
QSRPPQMLFKFLSPR	TEX28	321	O15482
KETLMTPIPFARPQD	TBC1D5	276	Q92609
DLKPLPPMTNRFREI	TUT4	936	Q5TAX3
LEVFFIPMDPRRKPE	USP11	496	P51784
PEPPVDFRVMEKDRA	ZRSR2	156	Q15696
RPDAPELPDFSMLKR	VPS33B	6	Q9H267
RGRMFPFDKLIIPEF	AK7	506	Q96M32
VMDRFFPLVPDLLSP	N6AMT1	151	Q9Y5N5