Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	ARM-type_fold	MROH9 PDS5B SAAL1 RTTN SCYL1 RICTOR ITPR1 THADA LTN1 EFR3B CAB39L	1.82e-06	339	99	11	IPR016024
Domain	ARM-like	MROH9 PDS5B SAAL1 RTTN SCYL1 RICTOR LTN1 EFR3B CAB39L	1.34e-05	270	99	9	IPR011989
Domain	-	MROH9 PDS5B SAAL1 RTTN SCYL1 RICTOR EFR3B CAB39L	2.38e-05	222	99	8	1.25.10.10
Domain	AT_hook	PDS5B ASH1L FAM171B	3.85e-04	27	99	3	SM00384
Domain	AT_hook_DNA-bd_motif	PDS5B ASH1L FAM171B	3.85e-04	27	99	3	IPR017956
Domain	PAM2	GSPT2 ATXN2	9.77e-04	9	99	2	PF07145
Domain	Ataxin-2_C	GSPT2 ATXN2	9.77e-04	9	99	2	IPR009818
Domain	Myotubularin-like_Pase_dom	MTM1 SBF2	2.43e-03	14	99	2	IPR010569
Domain	PPASE_MYOTUBULARIN	MTM1 SBF2	2.43e-03	14	99	2	PS51339
Domain	Myotubularin_fam	MTM1 SBF2	2.43e-03	14	99	2	IPR030564
Domain	Myotub-related	MTM1 SBF2	2.43e-03	14	99	2	PF06602
Domain	ADH_SHORT	DHRS1 DECR1 SDR16C5	2.79e-03	53	99	3	PS00061
Domain	adh_short	DHRS1 DECR1 SDR16C5	3.10e-03	55	99	3	PF00106
Domain	GRAM	MTM1 SBF2	3.18e-03	16	99	2	SM00568
Domain	SDR_fam	DHRS1 DECR1 SDR16C5	3.27e-03	56	99	3	IPR002347
Domain	Apc4_WD40_dom	COPA WDHD1	4.97e-03	20	99	2	IPR024977
Domain	ANAPC4_WD40	COPA WDHD1	4.97e-03	20	99	2	PF12894
Domain	RCC1	RCC1 HERC6	4.97e-03	20	99	2	PF00415
Domain	C2	CPNE2 CC2D1B SYT15 C2CD3	5.21e-03	131	99	4	PF00168
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	JCAD SAAL1 COPA ENTR1 RICTOR RCC1 FAM171B ERBIN ITPR1 C2CD3 SMG7 GSE1 ATXN2 AHNAK MTM1 SBF2 CCDC138 LTN1 EFR3B UTRN	4.54e-11	1049	105	20	27880917
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PDS5B COPA UBE4B TBC1D2 RICTOR RCC1 CHD7 ERBIN PRDM2 GSE1 WDHD1 ZNF644 SENP6 NOP2 CLUH	1.24e-08	774	105	15	15302935
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	PDS5B UBE4B SCYL1 PARP14 ERBIN GSE1 WDHD1 ZNF644 PRKACG NOP2	9.11e-08	341	105	10	32971831
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	SAAL1 ASH1L RICTOR CHD7 FAM171B ERBIN PRDM2 ITPR1 WDHD1 SBF2 TET1 LTN1 TMEM131 QSER1 POLK UTRN	1.65e-07	1084	105	16	11544199
Pubmed	Human transcription factor protein interaction networks.	COPA RB1 BICRA ENTR1 TWNK CHD7 ERBIN PRDM2 LDB1 SMG7 GSE1 ATXN2 ZNF644 CCDC138 N4BP1 QSER1 NOP2 MRPL1	2.70e-07	1429	105	18	35140242
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	FAM171B ERBIN SMG7 ATXN2 EFR3B TMEM131 N4BP1 UTRN	1.42e-06	263	105	8	34702444
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PDS5B COPA UBE4B RB1 POLE RICTOR RCC1 CHD7 ERBIN ZBED5 DECR1 AHNAK LTN1 DDX60L NOP2 UTRN	3.03e-06	1353	105	16	29467282
Pubmed	SerpinB2 protection of retinoblastoma protein from calpain enhances tumor cell survival.	RB1 SERPINB2	9.03e-06	2	105	2	18632617
Pubmed	Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium.	FCGR2C FCGR2B	9.03e-06	2	105	2	2531080
Pubmed	RABL2 Is Required for Hepatic Fatty Acid Homeostasis and Its Dysfunction Leads to Steatosis and a Diabetes-Like State.	RABL2B RABL2A	9.03e-06	2	105	2	27732084
Pubmed	The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein.	RB1 PRDM2	9.03e-06	2	105	2	7538672
Pubmed	Analysis of relative gene dosage and expression differences of the paralogs RABL2A and RABL2B by Pyrosequencing.	RABL2B RABL2A	9.03e-06	2	105	2	20138207
Pubmed	Inhibition of retinoblastoma protein degradation by interaction with the serpin plasminogen activator inhibitor 2 via a novel consensus motif.	RB1 SERPINB2	9.03e-06	2	105	2	12944478
Pubmed	Physiological up-regulation of inhibitory receptors Fc gamma RII and CR1 on memory B cells is lacking in SLE patients.	CR1 FCGR2B	9.03e-06	2	105	2	18182380
Pubmed	Expression of functional CD32 molecules on human NK cells is determined by an allelic polymorphism of the FcgammaRIIC gene.	FCGR2C FCGR2B	9.03e-06	2	105	2	9516136
Pubmed	Two novel human RAB genes with near identical sequence each map to a telomere-associated region: the subtelomeric region of 22q13.3 and the ancestral telomere band 2q13.	RABL2B RABL2A	9.03e-06	2	105	2	10444334
Pubmed	Variants in RABL2A causing male infertility and ciliopathy.	RABL2B RABL2A	9.03e-06	2	105	2	33075816
Pubmed	RABL2 positively controls localization of GPCRs in mammalian primary cilia.	RABL2B RABL2A	9.03e-06	2	105	2	30578315
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	ENTR1 SCYL1 SMG7 AHNAK CCDC138 LTN1 QSER1	9.23e-06	242	105	7	34011540
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	POLE ENTR1 TWNK RICTOR RCC1 SPG11 ERBIN ITPR1 THADA ZNF644 CCDC138 EFR3B TMEM131 NOP2 CLUH MRPL1	9.92e-06	1487	105	16	33957083
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	ZCWPW1 COPA RB1 EBF3 POLE TWNK RCC1 LDB1 GSE1 WDHD1 ZNF644 QSER1	1.11e-05	857	105	12	25609649
Pubmed	Interaction network of human early embryonic transcription factors.	BICRA CHD7 PRDM2 LDB1 GSE1 ZNF644 TET1 QSER1	1.18e-05	351	105	8	38297188
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	PDS5B RB1 BAZ2B CHD7 PRDM2 ZNF644 SENP6 CDYL QSER1 NOP2	1.61e-05	608	105	10	36089195
Pubmed	Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.	CARM1 PIGN RB1 LTN1 LPGAT1 N4BP1 NOP2	2.53e-05	283	105	7	21903422
Pubmed	Cytoplasmic and nuclear interaction between Rb family proteins and PAI-2: a physiological crosstalk in human corneal and conjunctival epithelial cells.	RB1 SERPINB2	2.70e-05	3	105	2	16397580
Pubmed	PRMT4-mediated arginine methylation negatively regulates retinoblastoma tumor suppressor protein and promotes E2F-1 dissociation.	CARM1 RB1	2.70e-05	3	105	2	25348716
Pubmed	Translesion synthesis DNA polymerases promote error-free replication through the minor-groove DNA adduct 3-deaza-3-methyladenine.	POLQ POLK	2.70e-05	3	105	2	28939775
Pubmed	In vitro analysis of the E1A-homologous sequences of RIZ.	RB1 PRDM2	2.70e-05	3	105	2	9223517
Pubmed	Nonallelic homologous recombination of the FCGR2/3 locus results in copy number variation and novel chimeric FCGR2 genes with aberrant functional expression.	FCGR2C FCGR2B	2.70e-05	3	105	2	26133275
Pubmed	Genomic pathology of SLE-associated copy-number variation at the FCGR2C/FCGR3B/FCGR2B locus.	FCGR2C FCGR2B	2.70e-05	3	105	2	23261299
Pubmed	Functional Fcgamma receptor polymorphisms are associated with human allergy.	FCGR2C FCGR2B	2.70e-05	3	105	2	24586589
Pubmed	NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein.	RB1 RCC1	2.70e-05	3	105	2	20668449
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PDS5B EBF3 BAZ2B BICRA RCC1 CHD7 PRDM2 GSE1 ATXN2 PSMG1 ZNF644 QSER1 NOP2	2.88e-05	1103	105	13	34189442
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	PDS5B BAZ2B BICRA RCC1 CHD7 ATXN2 AHNAK ZNF644 SENP6 QSER1 NOP2 MRPL1	3.19e-05	954	105	12	36373674
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	COPA RICTOR PARP14 TRIM64C AHNAK LTN1	3.56e-05	202	105	6	33005030
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RCC1 CHD7 PRDM2 GSE1 AHNAK ZNF644 TET1 UTRN	4.11e-05	418	105	8	34709266
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	COPA POLE SCYL1 TWNK FBXL4 ITPR1 DECR1 THADA ATXN2 ZNF644 CCDC138 TMEM131 NOP2 CLUH MRPL1	4.36e-05	1496	105	15	32877691
Pubmed	Endosomal phosphoinositides and human diseases.	MTM1 SBF2	5.40e-05	4	105	2	18429927
Pubmed	Regulation of glycoprotein Ib-IX-von Willebrand factor interaction by cAMP-dependent protein kinase-mediated phosphorylation at Ser 166 of glycoprotein Ib(beta).	VWF PRKACG	5.40e-05	4	105	2	12361948
Pubmed	Genome-wide ENU mutagenesis to reveal immune regulators.	RABL2B RABL2A	5.40e-05	4	105	2	11567631
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	PDS5B BAZ2B ZNF644 SENP6 POLQ POLK	6.01e-05	222	105	6	37071664
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	PDS5B COPA SERPINF1 RCC1 PARP14 DHRS1 DDX60L C9 NOP2 UTRN	6.03e-05	711	105	10	33022573
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	PDS5B PLK2 UBE4B RB1 HMOX1 GSE1 ATXN2 AHNAK ZNF644 ZNF566 LPGAT1 NOP2 CLUH	6.97e-05	1203	105	13	29180619
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	ENTR1 SPG11 CHD7 HMOX1 ERBIN WDHD1 TMEM131 N4BP1 QSER1 CLUH	7.76e-05	733	105	10	34672954
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CARM1 MROH9 RB1 BAZ2B TBC1D2 PARP14 PRDM2 GSE1 AHNAK UTRN	8.03e-05	736	105	10	29676528
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	POLE ENTR1 RICTOR WDHD1 UTRN	8.66e-05	147	105	5	29576527
Pubmed	The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer.	CARM1 RB1	8.97e-05	5	105	2	36690626
Pubmed	Involvement of the p97-Ufd1-Npl4 complex in the regulated endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors.	UBE4B ITPR1	8.97e-05	5	105	2	16103111
Pubmed	Copy number variation at the FCGR locus includes FCGR3A, FCGR2C and FCGR3B but not FCGR2A and FCGR2B.	FCGR2C FCGR2B	8.97e-05	5	105	2	19309690
Pubmed	Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.	RABL2B RABL2A	8.97e-05	5	105	2	33241915
Pubmed	Primordial germ cell DNA demethylation and development require DNA translesion synthesis.	POLQ POLK	8.97e-05	5	105	2	38702312
Pubmed	A pentamer transcriptional complex including tal-1 and retinoblastoma protein downmodulates c-kit expression in normal erythroblasts.	RB1 LDB1	8.97e-05	5	105	2	10866689
Pubmed	SNPs of Fc-gamma receptor genes and chronic periodontitis.	FCGR2C FCGR2B	8.97e-05	5	105	2	20439936
Pubmed	Copy number, linkage disequilibrium and disease association in the FCGR locus.	FCGR2C FCGR2B	8.97e-05	5	105	2	20508037
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	SAAL1 COPA RCC1 ERBIN ITPR1 DECR1 THADA LDB1 PSMG1 AHNAK LTN1 DDX60L NOP2 MRPL1	1.11e-04	1440	105	14	30833792
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PDS5B SCN11A COPA ASH1L TWNK CC2D1B RCC1 SPG11 ERBIN C2CD3 GSPT2 AHNAK CFAP74 POLQ	1.12e-04	1442	105	14	35575683
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	POLE ENTR1 SMG7 CCDC138 EFR3B N4BP1	1.18e-04	251	105	6	29778605
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	BAZ2B CC2D1B RICTOR THADA SBF2 LTN1 LPGAT1 N4BP1	1.29e-04	493	105	8	15368895
Pubmed	Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.	SCN11A CNTN1	1.34e-04	6	105	2	16029194
Pubmed	The Proliferating Cell Nuclear Antigen (PCNA)-interacting Protein (PIP) Motif of DNA Polymerase η Mediates Its Interaction with the C-terminal Domain of Rev1.	POLE POLK	1.34e-04	6	105	2	26903512
Pubmed	PtdIns5P regulation through evolution: roles in membrane trafficking?	MTM1 SBF2	1.34e-04	6	105	2	18774718
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	JCAD PLK2 VWF COPA UBE4B ASH1L ZBED5 LDB1 PSMG1 MTM1 SENP6 TMEM131 UTRN	1.34e-04	1285	105	13	35914814
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	RB1 ENTR1 ERBIN C2CD3 AHNAK CCDC138 CDYL NOP2 UTRN	1.52e-04	645	105	9	25281560
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	UBE4B SLC38A9 BICRA ASH1L ERBIN THADA LDB1 SMG7 ATXN2 SBF2 CAB39L QSER1 POLK UTRN	1.57e-04	1489	105	14	28611215
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	PDS5B COPA POLE CHD7 UTP25 AHNAK NOP2 UTRN CLUH	1.66e-04	653	105	9	22586326
Pubmed	Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.	ZCWPW1 CR1 ADAMTS20	1.93e-04	37	105	3	24162737
Pubmed	Proximity Mapping of CCP6 Reveals Its Association with Centrosome Organization and Cilium Assembly.	C2CD3 SMG7 CCDC138	2.09e-04	38	105	3	36674791
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	CARM1 SAAL1 RB1 POLE ENTR1 TWNK THADA LTN1	2.19e-04	533	105	8	25544563
Pubmed	The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.	VWF ITPR1 THADA CDYL	2.37e-04	99	105	4	19730683
Pubmed	Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages.	VWF RB1	2.50e-04	8	105	2	15616565
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	THADA SBF2 TET1 CFAP74	2.66e-04	102	105	4	11214970
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	UBE4B RICTOR ITPR1 LTN1	2.86e-04	104	105	4	31240132
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	CARM1 PDS5B COPA UBE4B POLE RCC1 WDHD1 PSMG1 LTN1	2.90e-04	704	105	9	29955894
Pubmed	Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells.	POLE POLK	3.21e-04	9	105	2	20227374
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	PIGN PDS5B SLC38A9 RTTN RICTOR THADA GSPT2 EFR3B UTRN	3.38e-04	719	105	9	35337019
Pubmed	Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.	PIGN SLC10A3 CHD7 RABL2B RABL2A SENP6	3.43e-04	306	105	6	18973680
Pubmed	Integrated Proteomics-Based Physical and Functional Mapping of AXL Kinase Signaling Pathways and Inhibitors Define Its Role in Cell Migration.	ERBIN AHNAK UTRN	3.69e-04	46	105	3	35022314
Pubmed	CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation.	ZNF644 CDYL	4.00e-04	10	105	2	19061646
Pubmed	BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy.	RB1 HMOX1	4.00e-04	10	105	2	17576813
Pubmed	Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice.	CR1 FCGR2B	4.00e-04	10	105	2	8422330
Pubmed	Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.	MTM1 SBF2	4.00e-04	10	105	2	9736772
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	RB1 ENTR1 CHD7 SMG7 GSE1 ZNF644 SENP6 POLK	4.22e-04	588	105	8	38580884
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	POLE ZNF644 QSER1 POLK	4.33e-04	116	105	4	30804394
Pubmed	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.	TBC1D2 WDHD1 AHNAK UTRN	4.62e-04	118	105	4	30979931
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	DHRS1 C2CD3 RABL2B RABL2A ATXN2 TMEM131 MRPL1	5.19e-04	462	105	7	31138677
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	UBE4B BICRA POLE RTTN TWNK SLC10A3 THADA C2CD3 AHNAK SBF2 FUT1	5.19e-04	1105	105	11	35748872
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	COPA TBC1D2 RCC1 PARP14 AHNAK NOP2	5.27e-04	332	105	6	37433992
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	IL16 RB1 BICRA ENTR1 ASH1L RICTOR THADA SMG7 GSE1 UTP25 LTN1	5.63e-04	1116	105	11	31753913
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	PDS5B POLE RCC1 CHD7 PARP14 WDHD1 AHNAK	5.67e-04	469	105	7	27634302
Pubmed	Amyotrophic lateral sclerosis: an update on recent genetic insights.	SPG11 ATXN2	5.84e-04	12	105	2	24085347
Pubmed	Trisomy 21 Alters DNA Methylation in Parent-of-Origin-Dependent and -Independent Manners.	PSMG1 TMEM131	5.84e-04	12	105	2	27100087
Pubmed	Role of Tet1 in erasure of genomic imprinting.	RASGRF1 TET1	5.84e-04	12	105	2	24291790
Pubmed	GORAB scaffolds COPI at the trans-Golgi for efficient enzyme recycling and correct protein glycosylation.	COPA SCYL1	5.84e-04	12	105	2	30631079
Pubmed	The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.	RABL2B RABL2A	5.84e-04	12	105	2	28625565
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	COPA BAZ2B PARP14 ITPR1 AHNAK NOP2	5.97e-04	340	105	6	29478914
Pubmed	The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.	PDS5B CC2D1B ATXN2 LTN1 UTRN	6.84e-04	230	105	5	35449600
Pubmed	Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China.	SULT2B1 FUT1	6.89e-04	13	105	2	24941225
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	CARM1 RB1 RICTOR FBXL4 GSE1 ZNF644 TET1	7.78e-04	495	105	7	27705803
Pubmed	Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay.	GSPT2 SMG7	8.02e-04	14	105	2	16452507
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	VWF SCYL1 GSPT2 AHNAK SERPINB2 UTRN	8.03e-04	360	105	6	33111431
GeneFamily	DNA polymerases	POLE POLQ POLK	8.92e-05	23	69	3	535
GeneFamily	RAB like GTPases	RABL2B RABL2A	1.42e-04	5	69	2	394
GeneFamily	Myotubularins\|Phosphoinositide phosphatases	MTM1 SBF2	1.46e-03	15	69	2	903
GeneFamily	DNA helicases	TWNK CHD7	1.88e-03	17	69	2	1167
GeneFamily	Short chain dehydrogenase/reductase superfamily	DHRS1 DECR1 SDR16C5	3.06e-03	76	69	3	743
Coexpression	GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_UP	CPNE2 BAZ2B RICTOR ITPR1 TET1 DNAI4 QSER1 POLK	3.96e-07	168	105	8	M6874
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	PDS5B RB1 BAZ2B SPG11 ITPR1 C2CD3 GSE1 WDHD1 ATXN2 LTN1 SERPINB2 CDYL TMEM131 N4BP1	8.25e-06	856	105	14	M4500
Coexpression	JAIN_NFKB_SIGNALING	RCC1 DECR1 SMG7 PSMG1 CLUH	1.29e-05	75	105	5	M17646
Coexpression	GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN	SPG11 DHRS1 ERBIN ZBED5 C2CD3 SENP6 AGBL2	1.54e-05	198	105	7	M7610
Coexpression	GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_UP	RB1 CHD7 PARP14 THADA UTP25 LPGAT1 AGBL2	1.59e-05	199	105	7	M9238
Coexpression	GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN	PDS5B UBE4B PARP14 PRDM2 ITPR1 WDHD1 ATXN2	1.64e-05	200	105	7	M291
Coexpression	GSE3203_UNTREATED_VS_IFNB_TREATED_LN_BCELL_DN	MUC15 RCC1 ITPR1 GSE1 AHNAK SBF2 C9	1.64e-05	200	105	7	M6789
Coexpression	ACEVEDO_LIVER_CANCER_DN	POLE SERPINF1 SCYL1 DHRS1 DECR1 GSE1 ATXN2 KANK4 C9 CLUH	6.35e-05	540	105	10	M7577
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ASH1L RICTOR PARP14 PRDM2 ITPR1 ZNF644 TMEM131 UTRN	1.58e-08	188	105	8	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	RICTOR PARP14 ERBIN ZNF644 N4BP1 DDX60L HERC6 UTRN	2.36e-08	198	105	8	44417089b62056269cac38d3134ff209c05b7007
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RICTOR PARP14 ERBIN ZNF644 N4BP1 DDX60L HERC6 UTRN	2.36e-08	198	105	8	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	RSV-Healthy-1\|Healthy / Virus stimulation, Condition and Cluster	IL16 TBC1D2 HMOX1 PARP14 AHNAK DDX60L HERC6	1.97e-07	175	105	7	ff3a27f512a3a710ebc863b7b75cce8167d5440b
ToppCell	RSV-Healthy-1\|RSV / Virus stimulation, Condition and Cluster	IL16 TBC1D2 HMOX1 PARP14 AHNAK DDX60L HERC6	1.97e-07	175	105	7	ca52b99b03535a5b3a2751d6981708dc5b255b91
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	BAZ2B ASH1L PARP14 ZNF644 N4BP1 DDX60L UTRN	2.67e-07	183	105	7	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ASH1L PARP14 PRDM2 AHNAK ZNF644 DDX60L UTRN	4.86e-07	200	105	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD VWF EBF3 BICRA SYT15 KANK4	4.23e-06	179	105	6	b7281160c84dd053a2981c9c76ea6cc6d2592cd5
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD COPA ASH1L HMOX1 ERBIN UTRN	5.12e-06	185	105	6	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPNE2 JCAD PLK2 VWF EBF3 UTRN	5.78e-06	189	105	6	b5fa3a619e3b554a1a45a551c9b6369075fe5615
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	MROH9 RABL2B RABL2A DNAI4 CFAP74 FYB2	5.78e-06	189	105	6	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	CF-Lymphoid-B_cell\|Lymphoid / Disease state, Lineage and Cell class	CHD7 PARP14 CR1 PRDM2 FCGR2B TMEM131	6.52e-06	193	105	6	7ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	RICTOR PARP14 ERBIN N4BP1 DDX60L UTRN	7.33e-06	197	105	6	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RTTN ASH1L RICTOR PARP14 ZNF644 UTRN	7.77e-06	199	105	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PLK2 VWF BAZ2B ASH1L CHD7 UTRN	7.99e-06	200	105	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	EBF3 SBF2 CCDC138 FUT1 CNTN1	2.67e-05	148	105	5	c240d506151fa90c59f40008c5fb31984c6f6f8f
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Cilia-bearing_cell\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	TBC1D2 CC2D1B CDYL ST8SIA5 AGBL2	4.36e-05	164	105	5	346e1530b4bf30adbcb2f7d64fdfb4cd8df69d7f
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLK2 VWF WDHD1 ATXN2 CDYL	5.02e-05	169	105	5	f086b50791e1c93e253eb5e8d6c4bf617b1416c3
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_2\|368C / Donor, Lineage, Cell class and subclass (all cells)	POLE CC2D1B FCGR2B SBF2 LTN1	5.31e-05	171	105	5	26b34dc069cc15b75a0c13cb8c5d81e074788160
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	PARP14 PRDM2 ITPR1 AHNAK LPGAT1	5.61e-05	173	105	5	d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 PARP14 N4BP1 HERC6 UTRN	6.26e-05	177	105	5	ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 PARP14 N4BP1 HERC6 UTRN	6.26e-05	177	105	5	f471f7747d6e8db7546899019af9508f48a14f89
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLK2 PARP14 N4BP1 HERC6 UTRN	6.26e-05	177	105	5	cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L PARP14 N4BP1 HERC6 UTRN	6.43e-05	178	105	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF3 SYT15 TET1 KANK4 CFAP74	6.43e-05	178	105	5	6bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CARM1 PLK2 FCGR2B LPGAT1 CLUH	6.60e-05	179	105	5	42f3c040f504a91cc69292d39d22b5715c12526f
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CARM1 PLK2 FCGR2B LPGAT1 CLUH	6.60e-05	179	105	5	063c05753ef1b4a18bc1ebbcae62c8cd25d11070
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MROH9 RABL2B RABL2A DNAI4 CFAP74	6.95e-05	181	105	5	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	MROH9 DNAI4 CFAP74 AGBL2 FYB2	7.14e-05	182	105	5	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HMOX1 CR1 FCGR2B AHNAK SERPINB2	7.51e-05	184	105	5	d1ea2b60fb1ca1a0b809d131310c43903a9e84ce
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD PLK2 VWF AHNAK UTRN	7.71e-05	185	105	5	7f46ea82a663181957f88e4e83114aef8a78820c
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD PLK2 VWF AHNAK UTRN	7.71e-05	185	105	5	956fb0043c0c3e4e5c4d6f58ff95faf6209c380e
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD PLK2 VWF AHNAK UTRN	7.91e-05	186	105	5	a58c9d1567da0961e0e295a156773d2252ee5a1a
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD VWF SERPINF1 SYT15 KANK4	8.11e-05	187	105	5	e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCell	SupraBC-Differ-KC\|World / shred by cell class for mouse tongue	MUC15 SULT2B1 SERPINB2 SDR16C5 CNTN1	8.53e-05	189	105	5	6412741b88e241304033b41effca0c77a374d907
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD PLK2 VWF EBF3 FCGR2B	8.53e-05	189	105	5	1d660bceee449aebf12fc9af4c74af246837b27a
ToppCell	Adult\|World / Lineage, Cell type, age group and donor	RASGRF1 TBC1D2 HMOX1 SDR16C5 FYB2	8.53e-05	189	105	5	5cd285bfad973125d46d704fec18b21266a63379
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PDS5B POLE WDHD1 CCDC138 POLQ	8.74e-05	190	105	5	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	BAZ2B SERPINF1 CHD7 DECR1 GSE1	8.96e-05	191	105	5	48cffb55c71bb8b34e926fc461fcd345ce43ea00
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like-IPCs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	BAZ2B SERPINF1 CHD7 DECR1 GSE1	8.96e-05	191	105	5	e4c1c533771b582e21683dbec6f93a558d865e00
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	MROH9 RABL2A DNAI4 CFAP74 FYB2	9.41e-05	193	105	5	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	JCAD PLK2 VWF BAZ2B SBF2	9.41e-05	193	105	5	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	JCAD PLK2 VWF BAZ2B SBF2	9.41e-05	193	105	5	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	MROH9 RABL2B RABL2A DNAI4 CFAP74	9.41e-05	193	105	5	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	POLE RTTN WDHD1 CCDC138 POLQ	9.41e-05	193	105	5	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPNE2 JCAD PLK2 EBF3 UTRN	9.41e-05	193	105	5	807fa1443b3c883cb318c71f4fca3c41d58f4910
ToppCell	COVID-19_Mild\|World / Disease condition and Cell class	RICTOR PARP14 N4BP1 DDX60L HERC6	9.41e-05	193	105	5	7256a5a491536c525b31ae96d47ab5c6303cb73a
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PARP14 CR1 PRDM2 ITPR1 FCGR2B	9.64e-05	194	105	5	ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IL16 PAMR1 EBF3 SERPINF1 CNTN1	9.64e-05	194	105	5	c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCell	PBMC-Mild\|PBMC / Compartment, Disease Groups and Clusters	RICTOR PARP14 ZNF644 DDX60L HERC6	9.64e-05	194	105	5	d1366b169d14011194e61d16b6b0953349febc78
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL16 RB1 PARP14 PRDM2 AHNAK	9.64e-05	194	105	5	d852aebf7a763b9a776c4570711f0c759f591910
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-cDC2-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ITPR1 FCGR2C FCGR2B AHNAK UTRN	9.87e-05	195	105	5	a2fe352682f548001ca2ee056e7a54af10134453
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RABL2B RABL2A DNAI4 CFAP74 AGBL2	9.87e-05	195	105	5	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RABL2B RABL2A DNAI4 CFAP74 AGBL2	9.87e-05	195	105	5	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	COVID-19-kidney-VWF+PLVAP+VCAM1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	JCAD PLK2 VWF SYT15 UTRN	1.01e-04	196	105	5	ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCell	CV-Moderate-1\|Moderate / Virus stimulation, Condition and Cluster	PARP14 N4BP1 DDX60L HERC6 UTRN	1.01e-04	196	105	5	b50cfcd87c5b67806450cb8b3c6860ab97f6d3b1
ToppCell	critical-Epithelial-Ciliated\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MUC15 RABL2B RABL2A DNAI4 CFAP74	1.01e-04	196	105	5	27b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell	Mild-CD8+_T_activated\|World / Disease group and Cell class	PARP14 N4BP1 DDX60L HERC6 UTRN	1.01e-04	196	105	5	79632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCell	Mild/Remission\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RICTOR PARP14 PRDM2 DDX60L HERC6	1.01e-04	196	105	5	71603a3b7df40eb3f267345f55e44a812fea7926
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COPA ASH1L ERBIN SMG7 UTRN	1.01e-04	196	105	5	151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCell	CV-Moderate-1\|CV / Virus stimulation, Condition and Cluster	PARP14 N4BP1 DDX60L HERC6 UTRN	1.04e-04	197	105	5	e3d00d850b4d191f9592ef993c0eaadfe5710b5f
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAMR1 EBF3 SERPINF1 AHNAK CNTN1	1.04e-04	197	105	5	2744cc94883c5d0424677cf5093bbab622933e9b
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAMR1 EBF3 SERPINF1 AHNAK CNTN1	1.06e-04	198	105	5	cfe2d52b19a1b4c2c2076fa1d5a69baf21a49623
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	POLE RTTN FAM171B WDHD1 POLQ	1.06e-04	198	105	5	d5e125f0c4f41b47d567568d0838adcca7655f6d
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAMR1 EBF3 SERPINF1 AHNAK CNTN1	1.09e-04	199	105	5	bfc157be6e9f84739848eb19b718de5b17f3fa88
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PAMR1 BAZ2B SERPINF1 GSPT2 CNTN1	1.09e-04	199	105	5	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD PLK2 VWF RB1 UTRN	1.09e-04	199	105	5	735e165580136576d39e18060550b57b8c808694
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD EBF3 SERPINF1 AHNAK CNTN1	1.09e-04	199	105	5	9846d6a31635fde759d55674631c11ab9270a603
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HMOX1 CR1 FCGR2C FCGR2B AHNAK	1.09e-04	199	105	5	f965eb89d6d023c83154276b8fded490fd89c100
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAMR1 EBF3 SERPINF1 AHNAK CNTN1	1.09e-04	199	105	5	83383d9ae4f501754fd3da0215ce6f0e3c70562c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HMOX1 CR1 FCGR2C FCGR2B AHNAK	1.09e-04	199	105	5	667b8b47a5b388506e3177b46747267fad8024f6
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HMOX1 CR1 FCGR2C FCGR2B SERPINB2	1.11e-04	200	105	5	3c9e0dc62d14cc00023f7f18053c1a13085d3413
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	PARP14 PRDM2 AHNAK N4BP1 UTRN	1.11e-04	200	105	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Neuron\|2m / Sample Type, Dataset, Time_group, and Cell type.	EBF3 BAZ2B CHD7 GSE1 ST8SIA5	1.11e-04	200	105	5	a581f1704a87b0390e1e2ff85053367d85247755
Drug	carmustine; Up 200; 100uM; MCF7; HT_HG-U133A	PDS5B ZCWPW1 HMOX1 FBXL4 WDHD1 MTM1 LPGAT1 SENP6 CDYL	2.08e-07	192	102	9	6914_UP
Drug	Monensin sodium salt [22373-78-0]; Down 200; 5.8uM; MCF7; HT_HG-U133A	ZCWPW1 BICRA RCC1 SMG7 SULT2B1 N4BP1 QSER1 HERC6	2.98e-06	197	102	8	3443_DN
Drug	Isradipine [75695-93-1]; Up 200; 10.8uM; PC3; HT_HG-U133A	RASGRF1 UBE4B ASH1L HMOX1 ITPR1 SMG7 PRKACG N4BP1	3.10e-06	198	102	8	6347_UP
Drug	tribromoethene	RB1 DECR1	1.99e-05	2	102	2	CID000011712
Drug	1,2,4-benzenetriol	PDS5B SERPINF1 DHRS1 DECR1 MTM1	2.35e-05	76	102	5	CID000010787
Drug	Proglumide [6620-60-6]; Up 200; 12uM; MCF7; HT_HG-U133A	JCAD COPA RASGRF1 RB1 RCC1 PRKACG DNAI4	2.47e-05	191	102	7	3861_UP
Drug	L-BVAU	POLE DECR1 POLQ POLK	2.49e-05	38	102	4	CID000667554
Drug	Medrysone [2668-66-8]; Down 200; 11.6uM; PC3; HT_HG-U133A	COPA UBE4B ITPR1 SULT2B1 SERPINB2 SENP6 N4BP1	2.82e-05	195	102	7	3705_DN
Drug	9-aminoacridine	POLE ITPR1 DECR1 POLQ POLK	2.83e-05	79	102	5	CID000007019
Drug	Merbromin [129-16-8]; Down 200; 5uM; MCF7; HT_HG-U133A	BICRA RCC1 HMOX1 SMG7 N4BP1 QSER1 HERC6	3.01e-05	197	102	7	3439_DN
Drug	Benserazide hydrochloride [14919-77-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A	BAZ2B BICRA RCC1 WDHD1 MTM1 LPGAT1 CDYL	3.01e-05	197	102	7	5322_DN
Drug	Nalidixic acid sodium salt hydrate; Up 200; 14.6uM; PC3; HT_HG-U133A	SCN11A ZCWPW1 PRDM2 LDB1 PRKACG SENP6 CNTN1	3.21e-05	199	102	7	7367_UP
Drug	rotenone; Up 200; 1uM; PC3; HT_HG-U133A	COPA ASH1L RCC1 SMG7 PRKACG SENP6 QSER1	3.21e-05	199	102	7	5920_UP
Drug	Evoxine [522-11-2]; Down 200; 11.6uM; PC3; HT_HG-U133A	PIGN CHD7 LDB1 GSE1 MTM1 SERPINB2 CDYL	3.21e-05	199	102	7	7380_DN
Drug	Epirizole [18694-40-1]; Down 200; 17uM; PC3; HT_HG-U133A	JCAD RCC1 HMOX1 ITPR1 SMG7 N4BP1 UTRN	3.21e-05	199	102	7	7292_DN
Disease	malaria (implicated_via_orthology)	HMOX1 FCGR2C FCGR2B	3.13e-06	9	100	3	DOID:12365 (implicated_via_orthology)
Disease	Prostatic Neoplasms	IL16 RB1 SERPINF1 TBC1D2 ASH1L CHD7 HMOX1 ITPR1 SULT2B1 SENP6 POLK	7.93e-06	616	100	11	C0033578
Disease	Malignant neoplasm of prostate	IL16 RB1 SERPINF1 TBC1D2 ASH1L CHD7 HMOX1 ITPR1 SULT2B1 SENP6 POLK	7.93e-06	616	100	11	C0376358
Disease	lymphocyte count	JCAD PLK2 IL16 SAAL1 UBE4B RB1 SLC38A9 CHD7 ITPR1 THADA ATXN2 AHNAK ZNF644 DDX60L AGBL2 SDR16C5	3.24e-05	1464	100	16	EFO_0004587
Disease	platelet component distribution width	PDS5B JCAD SCN11A ZCWPW1 VWF RTTN GSE1 FCGR2B ATXN2 AGBL2 POLK	5.13e-05	755	100	11	EFO_0007984
Disease	retinoblastoma (is_implicated_in)	RB1 SERPINF1	6.79e-05	4	100	2	DOID:768 (is_implicated_in)
Disease	serum gamma-glutamyl transferase measurement	JCAD BICRA ASH1L TWNK ITPR1 FCGR2C THADA GSE1 FCGR2B AHNAK FUT1	2.73e-04	914	100	11	EFO_0004532
Disease	Inherited neuropathies	TWNK SPG11 ITPR1	3.41e-04	40	100	3	C0598589
Disease	alpha fetoprotein measurement	TET1 CAB39L POLQ POLK	3.79e-04	100	100	4	EFO_0010583
Disease	Mitochondrial DNA Deletion Syndromes	TWNK FBXL4	4.03e-04	9	100	2	cv:CN043632
Disease	plexin-B2 measurement	FCGR2C FCGR2B	4.03e-04	9	100	2	EFO_0021867
Disease	birth weight	RB1 BAZ2B FCGR2C FCGR2B ATXN2 CCDC138 SDR16C5	4.27e-04	399	100	7	EFO_0004344
Disease	chronic fatigue syndrome (is_marker_for)	IL16 SERPINF1	5.03e-04	10	100	2	DOID:8544 (is_marker_for)
Disease	end stage renal disease (is_marker_for)	VWF CASR FCGR2B	5.16e-04	46	100	3	DOID:783 (is_marker_for)
Disease	immature platelet measurement	JCAD VWF RTTN GSE1	7.32e-04	119	100	4	EFO_0803541
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	ITPR1 ATXN2	7.34e-04	12	100	2	DOID:1441 (implicated_via_orthology)
Disease	urate measurement, bone density	UBE4B BAZ2B TBC1D2 ERBIN FBXL4 ITPR1 GSE1 UTRN	1.23e-03	619	100	8	EFO_0003923, EFO_0004531
Disease	Diabetic Angiopathies	SERPINF1 HMOX1	1.32e-03	16	100	2	C0011875
Disease	Malaria, susceptibility to	CR1 FCGR2B	1.32e-03	16	100	2	cv:C1970028
Disease	Microangiopathy, Diabetic	SERPINF1 HMOX1	1.32e-03	16	100	2	C0025945
Disease	–	CR1 FCGR2B	1.32e-03	16	100	2	611162
Disease	osteosarcoma (is_implicated_in)	RB1 SERPINF1	1.32e-03	16	100	2	DOID:3347 (is_implicated_in)
Disease	cortical thickness	PDS5B CHD7 THADA SMG7 ATXN2 ADAMTS20 TMEM131 QSER1 AGBL2 SDR16C5 CLUH	1.38e-03	1113	100	11	EFO_0004840
Disease	low affinity immunoglobulin gamma Fc region receptor II-a measurement	FCGR2C FCGR2B	1.50e-03	17	100	2	EFO_0021969
Disease	factor VIII measurement, Ischemic stroke	VWF ATXN2	1.87e-03	19	100	2	EFO_0004630, HP_0002140
Disease	acetate measurement	SPG11 ATXN2	2.08e-03	20	100	2	EFO_0010112
Disease	Malaria	CR1 FCGR2B	2.08e-03	20	100	2	C0024530
Disease	coagulation factor measurement	VWF CNTN1	2.08e-03	20	100	2	EFO_0004634
Disease	serum carcinoembryonic antigen measurement	SULT2B1 FUT1	2.08e-03	20	100	2	EFO_0005760
Disease	cancer (implicated_via_orthology)	RB1 POLE KANK4 CAB39L NOP2	2.22e-03	268	100	5	DOID:162 (implicated_via_orthology)
Disease	gut microbiome measurement, bone density	FCGR2C FCGR2B SENP6	2.39e-03	78	100	3	EFO_0003923, EFO_0007874
Disease	Immunologic Deficiency Syndromes	CHD7 C9	2.75e-03	23	100	2	C0021051
Disease	serum alanine aminotransferase measurement	PDS5B FCGR2C FCGR2B ATXN2 PSMG1 AHNAK TET1 LTN1 AGBL2	2.79e-03	869	100	9	EFO_0004735
Disease	malaria (is_implicated_in)	CR1 FCGR2B	2.99e-03	24	100	2	DOID:12365 (is_implicated_in)
Disease	late-onset Alzheimers disease	BICRA CR1 AHNAK ADAMTS20 CFAP74	3.21e-03	292	100	5	EFO_1001870
Disease	low affinity immunoglobulin gamma Fc region receptor II-b measurement	FCGR2C FCGR2B	3.24e-03	25	100	2	EFO_0021970

Protein segments in the cluster

Peptide	Gene	Start	Entry
FSKSLVSKIFGQPNF	nan	561	A8MVM7
KNQPKLIEFLSSFQK	CAB39L	296	Q9H9S4
KNLPFSFTKLQQLTA	ERBIN	381	Q96RT1
NFTSLFSNKPFLKLG	ASH1L	671	Q9NR48
TAINNLNPAFSKKFV	CPNE2	66	Q96FN4
TNLFLQKPGSFSKLS	BAZ2B	1456	Q9UIF8
KLPENFNEAKFITFS	CASR	796	P41180
NSPNFEEKKKFLTIF	GSE1	856	Q14687
FQNGKSKKFSRSDPN	FCGR2B	166	P31994
RFKLPKFNFSGSKVQ	AHNAK	3351	Q09666
KNADVLFSSFQKPKQ	CHD7	2611	Q9P2D1
NFLFNGNFLLSTSKK	ADAMTS20	771	P59510
FQTQKPLKSTSLSLF	RB1	636	P06400
FIPQNLTSFKNSTKS	RCC1	281	P18754
RFFTQPDKNFSNTKN	PDS5B	1096	Q9NTI5
QSSKKLFIFLGKSLF	SDR16C5	6	Q8N3Y7
ASFLDFLKSGPKQQF	QSER1	1151	Q2KHR3
FLKSGPKQQFSTLAV	QSER1	1156	Q2KHR3
NPKLDFFKNFLTSLV	LTN1	376	O94822
TQKSFNFAKKFSLPL	RABL2A	141	Q9UBK7
TQKSFNFAKKFSLPL	RABL2B	141	Q9UNT1
QAFAKKNNLPFLTNV	LPGAT1	196	Q92604
NSNSKKKSPASTFAL	LDB1	316	Q86U70
QPTLKFTNNSKLFPN	MUC15	211	Q8N387
QRFPFSDKEKNKLTF	ITPR1	851	Q14643
LPKQKEKNTSFRTFS	SBF2	1026	Q86WG5
DLKKFKNDFRLQPSS	ATXN2	796	Q99700
NSKQLFGQFLLKPVS	JCAD	811	Q9P266
PAKFQNANLSFSQSK	DDX60L	1481	Q5H9U9
SKSSNLLDLKNPFFR	CARM1	461	Q86X55
SAFSRKLNVNAKPFV	GSPT2	46	Q8IYD1
FQNGKSKKFSRSDPN	FCGR2C	166	P31995
KFSQLLLQVVKPFSF	SLC10A3	346	P09131
KPNLQILGTNSFVKF	EFR3B	111	Q9Y2G0
NPKFFGNLQSDDSKK	FAM214A	666	Q32MH5
SDFPFIFNSLSKIKL	HERC6	621	Q8IVU3
GKLEAQSSNFLFPKA	IL16	116	Q14005
SFPENFVFKTTNVKK	POLE	871	Q07864
FNKNSLTFSIPPKNK	TWNK	621	Q96RR1
LFLPKFKSKFQFLVS	MROH9	546	Q5TGP6
FKSKFQFLVSLPLNV	MROH9	551	Q5TGP6
DKNSFPFFASSKLVK	RICTOR	1081	Q6R327
SPFLRALKTQNFKDS	PSMG1	186	O95456
LASFLGFSKQSPQKK	PARP14	1401	Q460N5
TEALQSKFFSPLQKA	DECR1	36	Q16698
FPFLVKLQFSFKDNS	PRKACG	101	P22612
SADSFKKLPLNLASQ	C2CD3	2221	Q4AC94
NKPKTAAFFKSSNLP	CCDC138	476	Q96M89
LFAASQKFRKNTAPS	CDYL	166	Q9Y232
FAKLKTQTNASDFPI	CR1	501	P17927
FAKLKTQTNASDFPI	CR1	951	P17927
LNASFPKVFIKKSFT	FBXL4	606	Q9UKA2
ANPFSFREFLKTKNL	ENTR1	106	Q96C92
RTALNLFFKLKNFKT	COPA	1106	P53621
VQTFSQKTKKAPLNF	POLQ	1016	O75417
PSTAFQVKVKAFNNK	CNTN1	776	Q12860
VKNTNSPEFDQLFKL	CC2D1B	746	Q5T0F9
KRVSPISFFLSKFQN	ADGRF2	41	Q8IZF7
ASTLQKQPTFFKNSE	AGBL2	786	Q5U5Z8
KQPTFFKNSENSSFL	AGBL2	791	Q5U5Z8
SFASFTSFNPKKFIN	MS4A18	136	Q3C1V0
GLNNATQPKKSISFF	DNAI4	56	Q5VTH9
AKQAKFSTLPRNFSL	KANK4	61	Q5T7N3
FFTFPNIASATKFKQ	HMOX1	166	P09601
FSFSPANVISAVKQK	EBF3	546	Q9H4W6
KAFASNLPTLNVAKA	BICRA	1036	Q9NZM4
LQDPVLKQFKSAFSS	DHRS1	211	Q96LJ7
SKQKCSSAFQNLLPF	SAAL1	426	Q96ER3
PLLNFKSPSFFSKFN	SLC38A9	301	Q8NBW4
GFKLQNNSLLPIKFS	CFAP74	1366	Q9C0B2
KLADAKSQPSVQFSK	FAM171B	186	Q6P995
KTSNFNAAISLKFTP	C9	231	P02748
LPSSSFRSKQNVKFA	PRDM2	1546	Q13029
SAAFSKQKLQSAPTK	PAMR1	376	Q6UXH9
FKHLAKASPTQNLFL	SERPINB2	16	P05120
ANFTLPDSEFLKIFK	FUT1	326	P19526
KSNFLQNFLSLALPK	RTTN	2051	Q86VV8
LGQLFFSSKFQKLET	UTP25	221	Q68CQ4
EVSTKFQLFQKPANF	UTRN	1426	P46939
FLQSKTKRKTSNPQF	SYT15	196	Q9BQS2
KKVLASSLNSLPDFF	THADA	96	Q6YHU6
LPIQIFTKAFFSSKA	SULT2B1	126	O00204
QKFFQELSKSLDAFP	SCYL1	291	Q96KG9
ESFSPRNFFKTKKQN	FYB2	626	Q5VWT5
KFPFPAASTNLQKAL	SMG7	216	Q92540
FLFTTQKNTPLGTKL	ST8SIA5	116	O15466
IAKFKKFSNSIPQSQ	NOP2	581	P46087
KSVKNKNSSEFPLFS	RASGRF1	866	Q13972
NFFTNPTKNLVSITK	TET1	1401	Q8NFU7
LNQISPTFKKNFAVL	CLUH	286	O75153
NFFLKSKENLFNPSS	SPG11	546	Q96JI7
LKKFQILDFTSPKQS	MRPL1	106	Q9BYD6
KFKAPQSKALAASFS	ZCWPW1	546	Q9H0M4
NEFQLQLSPKTFASK	VWF	2066	P04275
LINSNKEKFKNPFYT	MTM1	501	Q13496
FFKVPVNKLAAAVSN	SERPINF1	46	P36955
KPLDFSTNQKLSAFA	WDHD1	1111	O75717
SSLSAQFKQNPKEVF	UBE4B	181	O95155
SSSKQFIKKFLSNKP	nan	126	Q6ZSR6
ISFDASKAKKPSQFS	TMEM131	391	Q92545
QSFQTSQPFQVLKKK	POLK	591	Q9UBT6
GIKNNISNFFAKIPF	SENP6	571	Q9GZR1
LFTPFKLLSDSKQFN	PIGN	386	O95427
FNKSQTSFHLKKPSA	TRAV3	86	A0A0B4J244
FPKNSALKQDVKRTF	ZNF644	651	Q9H582
KFISNSNKITFSKKP	ZBED5	91	Q49AG3
PSFTLQQIINSKKKF	ZNF566	156	Q969W8
QLFGRSFNSQKSPKL	SCN11A	721	Q9UI33
LSSPAKNFFKKAAAA	PLK2	356	Q9NYY3
KPNFNTNVALKKLAS	TRIM64C	61	A6NLI5
KLFLQKRFQSKSFPS	VRTN	656	Q9H8Y1
AQKAKRQNNTFPFFS	TBC1D2	281	Q9BYX2
QFVKLFENKENLPSS	N4BP1	136	O75113